ETR1

Summary

Gene Symbol: ETR1
Description: Signal transduction histidine kinase, hybrid-type, ethylene sensor
Alias: AtETR1, EIN1, ETHYLENE INSENSITIVE 1, ETHYLENE RESPONSE, ETHYLENE RESPONSE 1, ETR, HISTIDINE KINASE ETR1, T27F4.9, T27F4_9
Species: thale cress

Top Publications

  1. pmc REVERSION-TO-ETHYLENE SENSITIVITY1, a conserved gene that regulates ethylene receptor function in Arabidopsis
    Josephine S Resnick
    Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742, USA
    Proc Natl Acad Sci U S A 103:7917-22. 2006
  2. pmc Mutational analysis of the ethylene receptor ETR1. Role of the histidine kinase domain in dominant ethylene insensitivity
    Rebekah L Gamble
    Department of Biochemistry and Molecular Biology, University of New Hampshire, Durham, NH 03824, USA
    Plant Physiol 128:1428-38. 2002
  3. pmc Receptor signal output mediated by the ETR1 N terminus is primarily subfamily I receptor dependent
    Fang Xie
    National Key Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China
    Plant Physiol 142:492-508. 2006
  4. pmc ETHYLENE RESPONSE 1 histidine kinase activity of Arabidopsis promotes plant growth
    Young Hee Cho
    Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Plant Physiol 143:612-6. 2007
  5. pmc Heteromeric interactions among ethylene receptors mediate signaling in Arabidopsis
    Zhiyong Gao
    Department of Biological Sciences, Dartmouth College, Hanover, NH 03755, USA
    J Biol Chem 283:23801-10. 2008
  6. pmc Requirement of the histidine kinase domain for signal transduction by the ethylene receptor ETR1
    Xiang Qu
    Department of Biochemistry and Molecular Biology, University of New Hampshire, Durham, New Hampshire 03824, USA
    Plant Physiol 136:2961-70. 2004
  7. ncbi Ethylene-binding activity, gene expression levels, and receptor system output for ethylene receptor family members from Arabidopsis and tomato
    Ronan C O'Malley
    Department of Botany, University of Wisconsin, 430 Lincoln Drive, Madison, WI 53706, USA
    Plant J 41:651-9. 2005
  8. pmc Ethylene stimulates nutations that are dependent on the ETR1 receptor
    Brad M Binder
    Department of Botany, University of Wisconsin, Madison, Wisconsin 53706, USA
    Plant Physiol 142:1690-700. 2006
  9. pmc Identification of important regions for ethylene binding and signaling in the transmembrane domain of the ETR1 ethylene receptor of Arabidopsis
    Wuyi Wang
    Department of Botany, University of Wisconsin, Madison, Wisconsin 53706, USA
    Plant Cell 18:3429-42. 2006
  10. pmc A strong constitutive ethylene-response phenotype conferred on Arabidopsis plants containing null mutations in the ethylene receptors ETR1 and ERS1
    Xiang Qu
    Department of Biological Sciences, Dartmouth College, Hanover, NH 03755, USA
    BMC Plant Biol 7:3. 2007

Research Grants

Patents

  1. Xylanase, microorganisms for its production, DNA molecules, process of preparation and use thereof

Scientific Experts

  • D R Gallie
  • Xiang Qu
  • Iakovos S Pantelides
  • Patricia Moussatche
  • Brad M Binder
  • Chi Kuang Wen
  • Caren Chang
  • G Eric Schaller
  • Fang Xie
  • Georg Groth
  • Josephine S Resnick
  • Melanie M A Bisson
  • Young Hee Cho
  • Chun Hai Dong
  • Liping Qiu
  • Xue Chu Zhao
  • Radhika Desikan
  • Zhiyong Gao
  • Qian Liu
  • Wuyi Wang
  • Anthony B Bleecker
  • Benjamin Scharein
  • Maximo Rivarola
  • Yi Feng Chen
  • Jan Voet-van-Vormizeele
  • Klaus Harter
  • Stephen D Deslauriers
  • Congyao Xu
  • Arkadipta Bakshi
  • Xiao Min Ge
  • Randy F Lacey
  • Dorothea G Meldau
  • Qin Wang
  • J Peter Etchells
  • Brenda P Hall
  • Hubert Mayerhofer
  • Anne E Hall
  • Sang Dong Yoo
  • Nicole K Clay
  • Jana Cela
  • Qiu Ying Tian
  • Paul B Larsen
  • Christopher Grefen
  • Katherine Mary Warpeha
  • John T Hancock
  • Richard Hooley
  • Steven J Neill
  • Ronan C O'Malley
  • Jane Larkindale
  • Inga Mewis
  • Karolina M Pajerowska
  • Sheila D S Chiwocha
  • G E Schaller
  • Joseph J Kieber
  • Yevgeniya R Lapik
  • Patricia Leon
  • Yafan Huang
  • Jun Min He
  • Xue Zhou
  • Rebecca L Wilson
  • Ming Yue
  • Melynda D Randlett
  • Hong Li Cai
  • Xin Zhou
  • Sai Keerthana Wuppalapati
  • Xue Lei
  • Heejung Kim
  • Jennifer L Findell
  • Ashley A Alvarez
  • Rebekah L Gamble
  • Jesse D Cancel
  • Zhongming Yin
  • Wei Zhang
  • Stefan Meldau
  • Ian T Baldwin
  • Stefanie Underberg
  • Long H Hoang
  • Hendrik Wünsche
  • Simon R Turner
  • Saravanan Panneerselvam
  • Jing Yu
  • A B Bleecker
  • Samina N Shakeel
  • Claire M Provost
  • Jochen Mueller-Dieckmann
  • Noor Ul Haq
  • Geun Don Kim
  • Madiha Amir
  • Inhwan Hwang
  • Anuschka Malach

Detail Information

Publications65

  1. pmc REVERSION-TO-ETHYLENE SENSITIVITY1, a conserved gene that regulates ethylene receptor function in Arabidopsis
    Josephine S Resnick
    Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742, USA
    Proc Natl Acad Sci U S A 103:7917-22. 2006
    ..rte1 loss-of-function mutants have an enhanced ethylene response that closely resembles the etr1 null phenotype...
  2. pmc Mutational analysis of the ethylene receptor ETR1. Role of the histidine kinase domain in dominant ethylene insensitivity
    Rebekah L Gamble
    Department of Biochemistry and Molecular Biology, University of New Hampshire, Durham, NH 03824, USA
    Plant Physiol 128:1428-38. 2002
    The ethylene receptor family of Arabidopsis consists of five members, one of these being ETR1. The N-terminal half of ETR1 contains a hydrophobic domain responsible for ethylene binding and membrane localization...
  3. pmc Receptor signal output mediated by the ETR1 N terminus is primarily subfamily I receptor dependent
    Fang Xie
    National Key Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China
    Plant Physiol 142:492-508. 2006
    b>etr1-1 is a dominant ethylene receptor gene in Arabidopsis (Arabidopsis thaliana) and confers ethylene insensitivity...
  4. pmc ETHYLENE RESPONSE 1 histidine kinase activity of Arabidopsis promotes plant growth
    Young Hee Cho
    Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Plant Physiol 143:612-6. 2007
  5. pmc Heteromeric interactions among ethylene receptors mediate signaling in Arabidopsis
    Zhiyong Gao
    Department of Biological Sciences, Dartmouth College, Hanover, NH 03755, USA
    J Biol Chem 283:23801-10. 2008
    ..ethylene is perceived in Arabidopsis by a five member receptor family that consists of the subfamily 1 receptors ETR1 and ERS1 and the subfamily 2 receptors ETR2, ERS2, and EIN4...
  6. pmc Requirement of the histidine kinase domain for signal transduction by the ethylene receptor ETR1
    Xiang Qu
    Department of Biochemistry and Molecular Biology, University of New Hampshire, Durham, New Hampshire 03824, USA
    Plant Physiol 136:2961-70. 2004
    In Arabidopsis, ethylene is perceived by a receptor family consisting of five members, one of these being ETR1. The N-terminal half of ETR1 functions as a signal input domain...
  7. ncbi Ethylene-binding activity, gene expression levels, and receptor system output for ethylene receptor family members from Arabidopsis and tomato
    Ronan C O'Malley
    Department of Botany, University of Wisconsin, 430 Lincoln Drive, Madison, WI 53706, USA
    Plant J 41:651-9. 2005
    ....
  8. pmc Ethylene stimulates nutations that are dependent on the ETR1 receptor
    Brad M Binder
    Department of Botany, University of Wisconsin, Madison, Wisconsin 53706, USA
    Plant Physiol 142:1690-700. 2006
    ..Ethylene-stimulated nutations were also eliminated in etr1-7 loss-of-function mutants...
  9. pmc Identification of important regions for ethylene binding and signaling in the transmembrane domain of the ETR1 ethylene receptor of Arabidopsis
    Wuyi Wang
    Department of Botany, University of Wisconsin, Madison, Wisconsin 53706, USA
    Plant Cell 18:3429-42. 2006
    The ethylene binding domain (EBD) of the Arabidopsis thaliana ETR1 receptor is modeled as three membrane-spanning helices. We surveyed ethylene binding activity in different kingdoms and performed a bioinformatic analysis of the EBD...
  10. pmc A strong constitutive ethylene-response phenotype conferred on Arabidopsis plants containing null mutations in the ethylene receptors ETR1 and ERS1
    Xiang Qu
    Department of Biological Sciences, Dartmouth College, Hanover, NH 03755, USA
    BMC Plant Biol 7:3. 2007
    ..Subfamily 1 is composed of ETR1 and ERS1, and subfamily 2 is composed of ETR2, ERS2, and EIN4...
  11. pmc Subcellular co-localization of Arabidopsis RTE1 and ETR1 supports a regulatory role for RTE1 in ETR1 ethylene signaling
    Chun Hai Dong
    Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742, USA
    Plant J 53:275-86. 2008
    ..that RTE1 expression partly correlates with previously described sites of ETR1 expression or sites of ethylene response, such as the seedling root, root hairs and apical hook...
  12. ncbi Arabidopsis ethylene-response gene ETR1: similarity of product to two-component regulators
    C Chang
    Division of Biology 156 29, California Institute of Technology, Pasadena 91125
    Science 262:539-44. 1993
    ..Ethylene insensitivity is conferred by dominant mutations in the ETR1 gene early in the ethylene signal transduction pathway of Arabidopsis thaliana...
  13. pmc Involvement of RTE1 in conformational changes promoting ETR1 ethylene receptor signaling in Arabidopsis
    Josephine S Resnick
    Department of Cell Biology and Molecular Genetics, Bioscience Research Building, University of Maryland, College Park, MD 20742 5815, USA
    Plant J 56:423-31. 2008
    ..a novel gene conserved in plants, animals and some protists, was recently identified as a positive regulator of the ETR1 ethylene receptor...
  14. doi Subcellular localization and in vivo interactions of the Arabidopsis thaliana ethylene receptor family members
    Christopher Grefen
    Zentrum für Molekularbiologie der Pflanzen, Pflanzenphysiologie, Universitat Tubingen, Auf der Morgenstelle 1, 72076 Tubingen, Germany
    Mol Plant 1:308-20. 2008
    ..Our findings may have crucial functional implications on the ethylene receptor-mediated efficiency of hormone perception, induction of signaling, signal attenuation and output...
  15. doi Ethylene controls autophosphorylation of the histidine kinase domain in ethylene receptor ETR1
    Jan Voet-van-Vormizeele
    Heinrich Heine Universitat, Biochemie der Pflanzen, Universitatsstr 1, 40225 Dusseldorf, Germany
    Mol Plant 1:380-7. 2008
    ..In Arabidopsis, five ethylene receptor proteins are known, including ethylene resistant 1 (ETR1)...
  16. pmc Molecular association of the Arabidopsis ETR1 ethylene receptor and a regulator of ethylene signaling, RTE1
    Chun Hai Dong
    Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland 20742, USA
    J Biol Chem 285:40706-13. 2010
    ..Genetic analyses in Arabidopsis thaliana suggest that RTE1 promotes the signaling state of the ethylene receptor ETR1 through the ETR1 N-terminal domain...
  17. pmc Arabidopsis ETR1 and ERS1 differentially repress the ethylene response in combination with other ethylene receptor genes
    Qian Liu
    National Key Laboratory of Plant Molecular Genetics and National Center for Plant Gene Research, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China
    Plant Physiol 158:1193-207. 2012
    The ethylene response is negatively regulated by a family of five ethylene receptor genes in Arabidopsis (Arabidopsis thaliana)...
  18. pmc Arabidopsis RTE1 is essential to ethylene receptor ETR1 amino-terminal signaling independent of CTR1
    Liping Qiu
    National Key Laboratory of Plant Molecular Genetics and National Center for Plant Gene Research, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China
    Plant Physiol 159:1263-76. 2012
    ..ethylene receptor signaling, and the CTR1⁷⁻⁵⁶⁰ overexpressor CTR1-Nox showed a constitutive ethylene response phenotype. Expression of the ETR1 N terminus suppressed the CTR1-Nox phenotype...
  19. pmc Possible modulation of Arabidopsis ETR1 N-terminal signaling by CTR1
    Fang Xie
    National Key Laboratory of Plant Molecular Genetics and National Center for Plant Gene Research Shanghai, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
    Plant Signal Behav 7:1243-5. 2012
    ..mutations of CTR1 prevent ethylene receptor signaling, and corresponding ctr1 mutants show a constitutive ethylene response phenotype...
  20. ncbi Ethylene responses are negatively regulated by a receptor gene family in Arabidopsis thaliana
    J Hua
    Division of Biology, California Institute of Technology, Pasadena 91125, USA
    Cell 94:261-71. 1998
    ..had constitutive ethylene responses, revealing that these proteins negatively regulate ethylene responses and that the induction of ethylene response in Arabidopsis is through inactivation rather than activation of these proteins.
  21. pmc Analysis of combinatorial loss-of-function mutants in the Arabidopsis ethylene receptors reveals that the ers1 etr1 double mutant has severe developmental defects that are EIN2 dependent
    Anne E Hall
    Department of Botany, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    Plant Cell 15:2032-41. 2003
    ..On the other hand, light-grown seedlings and adult ers1 etr1 double mutants exhibited severe phenotypes such as miniature rosette size, delayed flowering, and sterility, ..
  22. ncbi A copper cofactor for the ethylene receptor ETR1 from Arabidopsis
    F I Rodriguez
    Department of Botany, 430 Lincoln Drive, University of Wisconsin, Madison, WI 53706, USA
    Science 283:996-8. 1999
    The ETR1 receptor from Arabidopsis binds the gaseous hormone ethylene. A copper ion associated with the ethylene-binding domain is required for high-affinity ethylene-binding activity...
  23. pmc Association of the Arabidopsis CTR1 Raf-like kinase with the ETR1 and ERS ethylene receptors
    K L Clark
    Department of Cell Biology and Molecular Genetics, H J Patterson Hall, University of Maryland, College Park, MD 20742, USA
    Proc Natl Acad Sci U S A 95:5401-6. 1998
    In Arabidopsis thaliana, signal transduction of the hormone ethylene involves at least two receptors, ETR1 and ERS, both of which are members of the two-component histidine protein kinase family that is prevalent in prokaryotes...
  24. ncbi Autophosphorylation activity of the Arabidopsis ethylene receptor multigene family
    Patricia Moussatche
    Plant Molecular and Cellular Biology Program, University of Florida, Gainesville, Florida 32611, USA
    J Biol Chem 279:48734-41. 2004
    ..It has been previously shown that a subfamily 1 Arabidopsis thaliana ethylene receptor, ETR1, autophosphorylates in vitro on a conserved histidine residue (1)...
  25. ncbi Possible His to Asp phosphorelay signaling in an Arabidopsis two-component system
    T Urao
    Biological Resources Division, Japan International Research Center for Agricultural Science JIRCAS, Ministry of Agriculture, Forestry and Fisheries, Ohwashi, Tsukuba, Ibaraki, Japan
    FEBS Lett 478:227-32. 2000
    ..We detected interactions between ETR1 and all ATHPs, and between CKI1 and ATHP1 or ATHP2. Interestingly, ERS1 could not interact with any ATHPs...
  26. ncbi Localization of the ethylene receptor ETR1 to the endoplasmic reticulum of Arabidopsis
    Yi Feng Chen
    Department of Biochemistry and Molecular Biology, University of New Hampshire, Durham, New Hampshire 03824, USA
    J Biol Chem 277:19861-6. 2002
    The ethylene receptor ETR1 of Arabidopsis contains transmembrane domains responsible for ethylene binding and membrane localization...
  27. pmc Loss-of-function mutations in the ethylene receptor ETR1 cause enhanced sensitivity and exaggerated response to ethylene in Arabidopsis
    Jesse D Cancel
    Department of Biochemistry, University of California, Riverside, California 92521, USA
    Plant Physiol 129:1557-67. 2002
    ..Triple and quadruple loss-of-function ethylene receptor mutants display a constitutive ethylene response phenotype, indicating they function as negative regulators in this pathway...
  28. ncbi Localization of the Raf-like kinase CTR1 to the endoplasmic reticulum of Arabidopsis through participation in ethylene receptor signaling complexes
    Zhiyong Gao
    Department of Biochemistry and Molecular Biology, University of New Hampshire, Durham, New Hampshire 03824, USA
    J Biol Chem 278:34725-32. 2003
    ..eliminate ethylene receptors and by a mutation in CTR1 that reduces its ability to bind to the ethylene receptor ETR1. Direct evidence that CTR1 is part of an ethylene receptor signaling complex was obtained by co-purification of the ..
  29. ncbi Ethylene-binding sites generated in yeast expressing the Arabidopsis ETR1 gene
    G E Schaller
    Department of Botany, University of Wisconsin, Madison 53706, USA
    Science 270:1809-11. 1995
    Mutations in the ETR1 gene of Arabidopsis thaliana confer insensitivity to ethylene, which indicates a role for the gene product in ethylene signal transduction...
  30. pmc Effect of ethylene pathway mutations upon expression of the ethylene receptor ETR1 from Arabidopsis
    Xue Chu Zhao
    Department of Biochemistry, University of New Hampshire, Durham 03824, USA
    Plant Physiol 130:1983-91. 2002
    ..backgrounds containing receptor loss-of-function mutations, ethylene-insensitive mutations, and constitutive ethylene response mutations...
  31. ncbi Biochemical and functional analysis of CTR1, a protein kinase that negatively regulates ethylene signaling in Arabidopsis
    Yafan Huang
    Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA
    Plant J 33:221-33. 2003
    CTR1 encodes a negative regulator of the ethylene response pathway in Arabidopsis thaliana. The C-terminal domain of CTR1 is similar to the Raf family of protein kinases, but its first two-thirds encodes a novel protein domain...
  32. pmc Canonical histidine kinase activity of the transmitter domain of the ETR1 ethylene receptor from Arabidopsis is not required for signal transmission
    Wuyi Wang
    Department of Botany and Laboratory of Genetics, University of Wisconsin, Madison 53706, USA
    Proc Natl Acad Sci U S A 100:352-7. 2003
    ..The double mutants exhibited a severe constitutive ethylene response phenotype consistent with the negative regulator model for receptor function...
  33. pmc Identification of Regions in the Receiver Domain of the ETHYLENE RESPONSE1 Ethylene Receptor of Arabidopsis Important for Functional Divergence
    Arkadipta Bakshi
    Genome Science and Technology Program A B, B M B and Department of Biochemistry, Cellular, and Molecular Biology R L W, R F L, H K, S K W, B M B, University of Tennessee, Knoxville, Tennessee 37996
    Plant Physiol 169:219-32. 2015
    ..However, the ETHYLENE RESPONSE1 (ETR1) ethylene receptor has unique, and sometimes contrasting, roles from the other receptor isoforms...
  34. pmc Plant vascular cell division is maintained by an interaction between PXY and ethylene signalling
    J Peter Etchells
    Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
    PLoS Genet 8:e1002997. 2012
    ..We propose a model whereby vascular cell division is regulated both by PXY signalling and ethylene/ERF signalling. Under normal circumstances, however, PXY signalling acts to repress the ethylene/ERF pathway...
  35. pmc Dimethyl disulfide produced by the naturally associated bacterium bacillus sp B55 promotes Nicotiana attenuata growth by enhancing sulfur nutrition
    Dorothea G Meldau
    Department of Molecular Ecology, Max Planck Institute for Chemical Ecology, 07745 Jena, Germany
    Plant Cell 25:2731-47. 2013
    ..promotes growth and survival of wild-type and, particularly, ethylene (ET)-insensitive (35)S-ethylene response1 (etr1) N. attenuata plants, which heterologously express the mutant Arabidopsis thaliana receptor ETR1-1...
  36. pmc HYPER RECOMBINATION1 of the THO/TREX complex plays a role in controlling transcription of the REVERSION-TO-ETHYLENE SENSITIVITY1 gene in Arabidopsis
    Congyao Xu
    National Key Laboratory of Plant Molecular Genetics and National Center for Plant Gene Research Shanghai, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
    PLoS Genet 11:e1004956. 2015
    ..by the hpr1-5 mutation, which indicates selectivity of HPR1 for RTE1 expression affecting the consequent ethylene response. Thus, components of the THO/TREX complex appear to have specific roles in the transcription or export of ..
  37. doi Heterotrimeric G protein mediates ethylene-induced stomatal closure via hydrogen peroxide synthesis in Arabidopsis
    Xiao Min Ge
    School of Life Sciences, Shaanxi Normal University, Xi an, 710062, China School of Life Sciences, Northwest University, Xi an, 710069, China
    Plant J 82:138-50. 2015
    ..Ethylene-triggered H2O2 generation and stomatal closure were impaired in RAN1, ETR1, ERS1 and EIN4 mutants but not impaired in ETR2 and ERS2 mutants...
  38. doi Dominant gain-of-function mutations in transmembrane domain III of ERS1 and ETR1 suggest a novel role for this domain in regulating the magnitude of ethylene response in Arabidopsis
    Stephen D Deslauriers
    Department of Biochemistry, University of California, Riverside, CA, 92521, USA
    New Phytol 208:442-55. 2015
    ..to the previously described etr1-2 mutation in the other Arabidopsis subfamily I ethylene receptor, ETHYLENE RESPONSE 1 (ETR1)...
  39. pmc Rice CONSTITUTIVE TRIPLE-RESPONSE2 is involved in the ethylene-receptor signalling and regulation of various aspects of rice growth and development
    Qin Wang
    National Key Laboratory of Plant Molecular Genetics and National Center for Plant Gene Research Shanghai, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 300 Fenglin Road, Shanghai 200032, PR China
    J Exp Bot 64:4863-75. 2013
    ..Arabidopsis ethylene receptors ETHYLENE RESPONSE1 and ETHYLENE RESPONSE SENSOR1 physically interacted with OsCTR2 on yeast two-hybrid assay, and green fluorescence protein-tagged ..
  40. pmc Histidine kinase activity of the ethylene receptor ETR1 facilitates the ethylene response in Arabidopsis
    Brenda P Hall
    Department of Biological Sciences, Dartmouth College, Hanover, New Hampshire 03755, USA
    Plant Physiol 159:682-95. 2012
    ..Subfamily 1 members ETHYLENE RESPONSE1 (ETR1) and ETHYLENE RESPONSE SENSOR1 (ERS1) have histidine kinase activity, unlike the subfamily 2 members ETR2, ERS2, and ETHYLENE ..
  41. pmc Giant chloroplast development in ethylene response1-1 is caused by a second mutation in ACCUMULATION AND REPLICATION OF CHLOROPLAST3 in Arabidopsis
    Young Hee Cho
    Department of Biological Science, Sungkyunkwan University, Suwon 440 746, Korea
    Mol Cells 33:99-103. 2012
    ..Here, we described an abnormal chloroplast phenotype in an ethylene insensitive ethylene response1-1 (etr1-1) of Arabidopsis thaliana...
  42. doi Protein kinase domain of CTR1 from Arabidopsis thaliana promotes ethylene receptor cross talk
    Hubert Mayerhofer
    EMBL Hamburg Outstation, Hamburg, Germany
    J Mol Biol 415:768-79. 2012
    ..This model provides a structural foundation for the observed high sensitivity of plants to ethylene...
  43. ncbi Histidine kinases in signal transduction pathways of eukaryotes
    W F Loomis
    Department of Biology, University of California San Diego, La Jolla 92093, USA
    J Cell Sci 110:1141-5. 1997
    ..Such signal transduction pathways can be expected to be found in a variety of eukaryotic differentiations since they are rapidly reversible and can integrate disparate signals...
  44. doi Ethylene is involved in nitrate-dependent root growth and branching in Arabidopsis thaliana
    Qiu Ying Tian
    State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, The Chinese Academy of Sciences, Beijing, China
    New Phytol 184:918-31. 2009
    ..change in root development in Arabidopsis thaliana using wild types and mutants defective in ethylene signaling (etr1, ein2) and nitrate transporters (chl1, nrt2.1)...
  45. pmc The copper transporter RAN1 is essential for biogenesis of ethylene receptors in Arabidopsis
    Brad M Binder
    Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, Tennessee 37996, USA
    J Biol Chem 285:37263-70. 2010
    ..In Arabidopsis thaliana, a small family of five receptor proteins typified by ETR1 mediates ethylene perception. Our previous work suggested that copper ions likely play a role in ethylene binding...
  46. doi New insight in ethylene signaling: autokinase activity of ETR1 modulates the interaction of receptors and EIN2
    Melanie M A Bisson
    Heinrich Heine Universitat Dusseldorf, Biochemie der Pflanzen, Universitatsstr 1, 40225 Dusseldorf, Germany
    Mol Plant 3:882-9. 2010
    ..an ethylene agonist, which is known to reduce auto-phosphorylation of the ethylene receptor ethylene resistant 1 (ETR1) or a mutation in the kinase domain of ETR1 that prevents auto-phosphorylation (H353A), increases the affinity of ..
  47. pmc Regulated ethylene insensitivity through the inducible expression of the Arabidopsis etr1-1 mutant ethylene receptor in tomato
    Daniel R Gallie
    Department of Biochemistry, University of California, Riverside, California 92521 0129, USA
    Plant Physiol 152:1928-39. 2010
    ..One such mutant, ethylene resistant1-1 (etr1-1), results in a strong ethylene-insensitive phenotype in Arabidopsis...
  48. ncbi Effect of salt and osmotic stress upon expression of the ethylene receptor ETR1 in Arabidopsis thaliana
    Xue Chu Zhao
    Department of Biochemistry and Molecular Biology, University of New Hampshire, Durham, NH 03824, USA
    FEBS Lett 562:189-92. 2004
    ..Here we report that exposure of Arabidopsis plants to NaCl reduced expression of the ethylene receptor ETR1. The change in gene expression was reflected at the protein level based on immunoblot analysis...
  49. pmc A role for ETR1 in hydrogen peroxide signaling in stomatal guard cells
    Radhika Desikan
    Centre for Research in Plant Science, Genomics Research Institute, University of the West of England, Bristol BS16 1QY, United Kingdom
    Plant Physiol 137:831-4. 2005
  50. ncbi The etr1-2 mutation in Arabidopsis thaliana affects the abscisic acid, auxin, cytokinin and gibberellin metabolic pathways during maintenance of seed dormancy, moist-chilling and germination
    Sheila D S Chiwocha
    Department of Biological Sciences, Simon Fraser University, Burnaby, BC, Canada V5A 1S6
    Plant J 42:35-48. 2005
    In Arabidopsis thaliana, the etr1-2 mutation confers dominant ethylene insensitivity and results in a greater proportion of mature seeds that exhibit dormancy compared with mature seeds of the wild-type...
  51. pmc Heat stress phenotypes of Arabidopsis mutants implicate multiple signaling pathways in the acquisition of thermotolerance
    Jane Larkindale
    Department of Biochemistry and Molecular Biophysics, University of Arizona, Tucson, Arizona 85721, USA
    Plant Physiol 138:882-97. 2005
    ..Ethylene signaling mutants (ein2 and etr1) and reactive oxygen metabolism mutants (vtc1, vtc2, npq1, and cad2) were more defective in basal than acquired ..
  52. pmc Major signaling pathways modulate Arabidopsis glucosinolate accumulation and response to both phloem-feeding and chewing insects
    Inga Mewis
    Department of Entomology, Chemical Ecology Laboratory, Pennsylvania State University, State College, Pennsylvania 16802, USA
    Plant Physiol 138:1149-62. 2005
    ..There was no significant impact on constitutive GS contents of blocking ET signaling (at ET resistant [etr1]) or reducing SA concentrations (nahG transgene)...
  53. ncbi Potato homologs of Arabidopsis thaliana genes functional in defense signaling--identification, genetic mapping, and molecular cloning
    Karolina M Pajerowska
    Max Planck Institute for Plant Breeding Research, Cologne, Germany
    Mol Plant Microbe Interact 18:1107-19. 2005
    ..Our results form the basis for further studies on the contributions of these candidate genes to natural variation of potato disease resistance...
  54. pmc G-protein-coupled receptor 1, G-protein Galpha-subunit 1, and prephenate dehydratase 1 are required for blue light-induced production of phenylalanine in etiolated Arabidopsis
    Katherine Mary Warpeha
    Laboratory for Molecular Biology, Department of Biological Sciences, University of Illinois, Chicago, 60607, USA
    Plant Physiol 140:844-55. 2006
    ..An additional outcome of the work is the confirmation that phenylpyruvate acts as the intermediate in the synthesis of Phe in etiolated plants, as it commonly does in bacteria and fungi...
  55. pmc The Arabidopsis cupin domain protein AtPirin1 interacts with the G protein alpha-subunit GPA1 and regulates seed germination and early seedling development
    Yevgeniya R Lapik
    Laboratory for Molecular Biology, Department of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois 60607, USA
    Plant Cell 15:1578-90. 2003
    ..These data indicate that AtPirin1 likely functions immediately downstream of GPA1 in regulating seed germination and early seedling development...
  56. ncbi Ethylene-induced stomatal closure in Arabidopsis occurs via AtrbohF-mediated hydrogen peroxide synthesis
    Radhika Desikan
    Centre for Research in Plant Science, Genomics Research Institute, Faculty of Applied Sciences, University of the West of England, Bristol, Coldharbour Lane, Bristol BS16 1QY, UK
    Plant J 47:907-16. 2006
    ..Ethylene-induced closure is inhibited by the ethylene antagonists 1-MCP and silver. The ethylene receptor mutants etr1-1 and etr1-3 are insensitive to ethylene in terms of stomatal closure and H(2)O(2) production...
  57. ncbi Sugar and hormone connections
    Patricia Leon
    Departamento de Biologia Molecular de Plantas, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos 62271, Mexico
    Trends Plant Sci 8:110-6. 2003
    ..The effects of sugar and osmotic stress on morphogenesis and gene expression are distinct. The plasticity of plant growth and development are exemplified by the complex interplay of sugar and hormone signalling...
  58. doi Ethylene signaling: identification of a putative ETR1-AHP1 phosphorelay complex by fluorescence spectroscopy
    Benjamin Scharein
    Biochemie der Pflanzen, Heinrich Heine Universitat, Universitatsstr 1, 40225 Dusseldorf, Germany
    Anal Biochem 377:72-6. 2008
    The plant ethylene receptor ETR1, which shows substantial sequence homology to typical bacterial histidine kinases, is involved in the coordination of several growth and development processes...
  59. pmc Glucosinolate metabolites required for an Arabidopsis innate immune response
    Nicole K Clay
    Department of Genetics, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA
    Science 323:95-101. 2009
    ..Our study shows that well-studied plant metabolites, previously identified as important in avoiding damage by herbivores, are also required as a component of the plant defense response against microbial pathogens...
  60. doi Ethylene signaling may be involved in the regulation of tocopherol biosynthesis in Arabidopsis thaliana
    Jana Cela
    Departament de Biologia Vegetal, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    FEBS Lett 583:992-6. 2009
    Tocopherol biosynthesis was investigated in ein3-1, etr1-1 and eto1-1 mutants of Arabidopsis thaliana, which show a defect in ethylene signaling, perception and over-produce ethylene, respectively...
  61. doi EIN2, the central regulator of ethylene signalling, is localized at the ER membrane where it interacts with the ethylene receptor ETR1
    Melanie M A Bisson
    Department of Plant Biochemistry, Heinrich Heine University, 40225 Dusseldorf, Universitatsstrasse 1, Germany
    Biochem J 424:1-6. 2009
    ..Here we show, by an integrated approach using in vivo and in vitro fluorescence techniques, that EIN2 is localized at the ER (endoplasmic reticulum) membrane where it shows specific interaction with the ethylene receptor protein ETR1.
  62. doi Ethylene perception via ETR1 is required in Arabidopsis infection by Verticillium dahliae
    Iakovos S Pantelides
    Laboratory of Plant Pathology, Department of Crop Science, Agricultural University of Athens, 75 Iera Odos, 118 55 Athens, Greece
    Mol Plant Pathol 11:191-202. 2010
    ..Analysis of the mutant responses revealed enhanced resistance in etr1-1[ethylene (ET) receptor mutant] plants, but not in salicylic acid-, jasmonic acid- or other ET-deficient mutants, ..
  63. ncbi The ethylene response mediator ETR1 from Arabidopsis forms a disulfide-linked dimer
    G E Schaller
    Department of Botany, University of Wisconsin, Madison 53706, USA
    J Biol Chem 270:12526-30. 1995
    Mutations in the ETR1 gene of the higher plant Arabidopsis confer insensitivity to ethylene, indicating a role for the gene product in ethylene signal perception and transduction...

Research Grants1

  1. Cell Fate Decision by CLV1 in Shoot Apical Meristem
    Xiang Qu; Fiscal Year: 2007
    ..unreadable] [unreadable]..

Patents1

  1. Xylanase, microorganisms for its production, DNA molecules, process of preparation and use thereof
    Patent Number: EP0698667-A1; Date:1996-02-28