NUDT7

Summary

Gene Symbol: NUDT7
Description: MutT/nudix family protein
Alias: ATNUDX7, Arabidopsis thaliana Nudix hydrolase homolog 7, AtNUDT7, GFG1, GROWTH FACTOR GENE 1, T20K18.70, T20K18_70
Species: thale cress

Top Publications

  1. ncbi Analysis of Arabidopsis growth factor gene 1 (GFG1) encoding a nudix hydrolase during oxidative signaling
    Niranjani Jambunathan
    Department of Biochemistry and Molecular Biology, 246 Noble Research Center, Oklahoma State University, Stillwater, OK 74078, USA
    Planta 224:1-11. 2006
  2. ncbi Comprehensive analysis of cytosolic Nudix hydrolases in Arabidopsis thaliana
    Takahisa Ogawa
    Department of Advanced Bioscience, Faculty of Agriculture, Kinki University, 3327 204 Nakamachi, Nara 631 8505, Japan
    J Biol Chem 280:25277-83. 2005
  3. pmc Salicylic acid-independent ENHANCED DISEASE SUSCEPTIBILITY1 signaling in Arabidopsis immunity and cell death is regulated by the monooxygenase FMO1 and the Nudix hydrolase NUDT7
    Michael Bartsch
    Department of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, D 50829 Cologne, Germany
    Plant Cell 18:1038-51. 2006
  4. pmc AtNUDT7, a negative regulator of basal immunity in Arabidopsis, modulates two distinct defense response pathways and is involved in maintaining redox homeostasis
    Xiaochun Ge
    Donald Danforth Plant Science Center, St Louis, MO 63132, USA
    Plant Physiol 145:204-15. 2007
  5. ncbi Mutational analysis of the AtNUDT7 Nudix hydrolase from Arabidopsis thaliana reveals residues required for protein quaternary structure formation and activity
    Kamil Olejnik
    Department of Plant Biochemistry, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warszawa, Poland
    Acta Biochim Pol 56:291-300. 2009
  6. pmc Modulation of the poly(ADP-ribosyl)ation reaction via the Arabidopsis ADP-ribose/NADH pyrophosphohydrolase, AtNUDX7, is involved in the response to oxidative stress
    Kazuya Ishikawa
    Department of Advanced Bioscience, Faculty of Agriculture, Kinki University, Nara 631 8505, Japan
    Plant Physiol 151:741-54. 2009
  7. doi Discovery of ADP-ribosylation and other plant defense pathway elements through expression profiling of four different Arabidopsis-Pseudomonas R-avr interactions
    Lori Adams-Phillips
    Department of Plant Pathology, University of Wisconsin Madison, Madison, WI 53706, USA
    Mol Plant Microbe Interact 21:646-57. 2008
  8. doi Arabidopsis nudix hydrolase 7 plays a role in seed germination
    Xin Zeng
    Department of Biochemistry and Molecular Biology, 246 Noble Research Center, Oklahoma State University, Stillwater, OK, 74078, USA
    Planta 239:1015-25. 2014
  9. doi A GCC-box motif in the promoter of nudix hydrolase 7 (AtNUDT7) gene plays a role in ozone response of Arabidopsis ecotypes
    Meenakumari Muthuramalingam
    Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, OK 74078, USA
    Genomics 105:31-8. 2015
  10. ncbi Cloning, expression and characterization of a Nudix hydrolase that catalyzes the hydrolytic breakdown of ADP-glucose linked to starch biosynthesis in Arabidopsis thaliana
    Francisco José Muñoz
    Instituto de Agrobiotecnologia, Universidad Pública de Navarra Consejo Superior de Investigaciones Científicas Gobierno de Navarra, Ctra Mutilva s n, 31192 Mutilva Baja, Navarra, Spain
    Plant Cell Physiol 47:926-34. 2006

Scientific Experts

  • Nora Alonso-Casajús
  • Kamil Olejnik
  • Ramamurthy Mahalingam
  • Xin Zeng
  • Niranjani Jambunathan
  • Elzbieta Kraszewska
  • Meenakumari Muthuramalingam
  • Takahisa Ogawa
  • Kazuya Ishikawa
  • Lori Adams-Phillips
  • Kazuya Yoshimura
  • Xiaochun Ge
  • Shigeru Shigeoka
  • Francisco José Muñoz
  • Michael Bartsch
  • Peter Klein
  • Niranjani J Iyer
  • Yong Fang Li
  • Agata Lipko
  • Maria Bucholc
  • Martyna Kujawa
  • Agnieszka Augustyn
  • Marta Modzelan
  • Anna Anielska-Mazur
  • Yuhong Tang
  • Anuradha Penaganti
  • Eiichiro Fukusaki
  • Eisuke Hirosue
  • Grazyna Goch
  • Wiesław I Gruszecki
  • Teresa Basinska
  • Kazuo Harada
  • Danuta Płochocka
  • Marcin Grynberg
  • Yasumune Nakayama
  • Richard W Michelmore
  • F Mark Dunning
  • Jinrong Wan
  • Xiaoping Tan
  • Andrew F Bent
  • Blake C Meyers
  • Yiji Xia
  • Sheng bing Wang
  • Xun Wang
  • Tong Zhu
  • Huifen Zhu
  • Guo Jing Li
  • Jaqueline Bautor
  • Svenja Debey
  • Pawel Bednarek
  • Joachim L Schultze
  • Jane E Parker
  • María Teresa Morán-Zorzano
  • Enrico Gobbato
  • Javier Pozueta-Romero
  • Edurne Baroja-Fernandez
  • Yayoi Ueda

Detail Information

Publications13

  1. ncbi Analysis of Arabidopsis growth factor gene 1 (GFG1) encoding a nudix hydrolase during oxidative signaling
    Niranjani Jambunathan
    Department of Biochemistry and Molecular Biology, 246 Noble Research Center, Oklahoma State University, Stillwater, OK 74078, USA
    Planta 224:1-11. 2006
    ..We demonstrate that Arabidopsis Growth Factor Gene 1 (GFG1; At4g12720) encoding a nudix hydrolase, is an NADH pyrophosphatase and ADP-ribose pyrophosphatase...
  2. ncbi Comprehensive analysis of cytosolic Nudix hydrolases in Arabidopsis thaliana
    Takahisa Ogawa
    Department of Advanced Bioscience, Faculty of Agriculture, Kinki University, 3327 204 Nakamachi, Nara 631 8505, Japan
    J Biol Chem 280:25277-83. 2005
    ..coli MutT in A. thaliana and is involved in the prevention of spontaneous mutation. The results obtained here suggest that the plant Nudix family has evolved in a specific manner that differs from that of yeast and humans...
  3. pmc Salicylic acid-independent ENHANCED DISEASE SUSCEPTIBILITY1 signaling in Arabidopsis immunity and cell death is regulated by the monooxygenase FMO1 and the Nudix hydrolase NUDT7
    Michael Bartsch
    Department of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, D 50829 Cologne, Germany
    Plant Cell 18:1038-51. 2006
    ..FLAVIN-DEPENDENT MONOOXYGENASE1 (FMO1) positively regulates the EDS1 pathway, and one member (NUDT7) of a family of cytosolic Nudix hydrolases exerts negative control of EDS1 signaling...
  4. pmc AtNUDT7, a negative regulator of basal immunity in Arabidopsis, modulates two distinct defense response pathways and is involved in maintaining redox homeostasis
    Xiaochun Ge
    Donald Danforth Plant Science Center, St Louis, MO 63132, USA
    Plant Physiol 145:204-15. 2007
    ..b>AtNUDT7, a Nudix domain-containing protein in Arabidopsis (Arabidopsis thaliana) that hydrolyzes nucleotide derivatives, ..
  5. ncbi Mutational analysis of the AtNUDT7 Nudix hydrolase from Arabidopsis thaliana reveals residues required for protein quaternary structure formation and activity
    Kamil Olejnik
    Department of Plant Biochemistry, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warszawa, Poland
    Acta Biochim Pol 56:291-300. 2009
    Arabidopsis thaliana AtNUDT7, a homodimeric Nudix hydrolase active on ADP-ribose and NADH, exerts negative control on the major signaling complex involved in plant defense activation and programmed cell death...
  6. pmc Modulation of the poly(ADP-ribosyl)ation reaction via the Arabidopsis ADP-ribose/NADH pyrophosphohydrolase, AtNUDX7, is involved in the response to oxidative stress
    Kazuya Ishikawa
    Department of Advanced Bioscience, Faculty of Agriculture, Kinki University, Nara 631 8505, Japan
    Plant Physiol 151:741-54. 2009
    ..PAR) reaction by an Arabidopsis (Arabidopsis thaliana) ADP-ribose (Rib)/NADH pyrophosphohydrolase, AtNUDX7 (for Arabidopsis Nudix hydrolase 7), in AtNUDX7-overexpressed (Pro(35S):AtNUDX7) or AtNUDX7-disrupted (KO-nudx7) ..
  7. doi Discovery of ADP-ribosylation and other plant defense pathway elements through expression profiling of four different Arabidopsis-Pseudomonas R-avr interactions
    Lori Adams-Phillips
    Department of Plant Pathology, University of Wisconsin Madison, Madison, WI 53706, USA
    Mol Plant Microbe Interact 21:646-57. 2008
    ..in plant defense responses was suggested initially by the upregulated expression of genes encoding NUDT7 and poly(ADP-ribose) glycohydrolase in multiple R-avr interactions...
  8. doi Arabidopsis nudix hydrolase 7 plays a role in seed germination
    Xin Zeng
    Department of Biochemistry and Molecular Biology, 246 Noble Research Center, Oklahoma State University, Stillwater, OK, 74078, USA
    Planta 239:1015-25. 2014
    Arabidopsis nudix hydrolase 7 (Atnudt7) mutants exhibit reduced seed germination phenotype following after-ripening. The role of AtNUDT7 in seeds and during early stages of imbibition was examined...
  9. doi A GCC-box motif in the promoter of nudix hydrolase 7 (AtNUDT7) gene plays a role in ozone response of Arabidopsis ecotypes
    Meenakumari Muthuramalingam
    Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, OK 74078, USA
    Genomics 105:31-8. 2015
    Arabidopsis nudix hydrolase 7 (AtNudt7) plays an important role in regulating redox homeostasis during stress/defense signaling and seed germination...
  10. ncbi Cloning, expression and characterization of a Nudix hydrolase that catalyzes the hydrolytic breakdown of ADP-glucose linked to starch biosynthesis in Arabidopsis thaliana
    Francisco José Muñoz
    Instituto de Agrobiotecnologia, Universidad Pública de Navarra Consejo Superior de Investigaciones Científicas Gobierno de Navarra, Ctra Mutilva s n, 31192 Mutilva Baja, Navarra, Spain
    Plant Cell Physiol 47:926-34. 2006
    ..The overall information provides the first evidence for the existence of plant Nudix hydrolases that have access to an intracellular pool of ADP-glucose linked to starch biosynthesis...
  11. ncbi Cloning and characterization of an Arabidopsis thaliana Nudix hydrolase homologous to the mammalian GFG protein
    Kamil Olejnik
    The Department of Plant Biochemistry, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5A, 02 106 Warsaw, Poland
    Biochim Biophys Acta 1752:133-41. 2005
    ..2 mM and 2.7 s(-1) respectively. The products of ADP-ribose hydrolysis were AMP and ribose-5-phosphate. The optimal activity was at alkaline pH (8.5) with Mg2+ (5 mM) ions as the cofactor. The protein exists as a dimmer in solution...
  12. pmc Modulation of redox homeostasis under suboptimal conditions by Arabidopsis nudix hydrolase 7
    Niranjani Jambunathan
    246 Noble Research Center, Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, Oklahoma, USA
    BMC Plant Biol 10:173. 2010
    ..Several independent studies have demonstrated that Arabidopsis nudix hydrolase 7 (AtNUDT7) hydrolyzes NADH and ADP-ribose...
  13. ncbi Arabidopsis thaliana Nudix hydrolase AtNUDT7 forms complexes with the regulatory RACK1A protein and Ggamma subunits of the signal transducing heterotrimeric G protein
    Kamil Olejnik
    Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warszawa, Poland
    Acta Biochim Pol 58:609-16. 2011
    Arabidopsis thaliana AtNUDT7 Nudix pyrophosphatase hydrolyzes NADH and ADP-ribose in vitro and is an important factor in the cellular response to diverse biotic and abiotic stresses...