Gene Symbol: NUDX1
Description: nudix hydrolase 1
Alias: ARABIDOPSIS THALIANA NUDIX HYDROLASE HOMOLOG 1, ATNUDT1, ATNUDX1, F14K14.13, F14K14_13, NUDIX HYDROLASE 1, nudix hydrolase 1, nudix hydrolase 1, nudix hydrolase 1
Species: thale cress
- Yoshimura K, Ogawa T, Ueda Y, Shigeoka S. AtNUDX1, an 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate pyrophosphohydrolase, is responsible for eliminating oxidized nucleotides in Arabidopsis. Plant Cell Physiol. 2007;48:1438-49 pubmed..Previously, we have reported that an Arabidopsis Nudix hydrolase, AtNUDX1, acts to hydrolyze an oxidized deoxyribonucleotide, 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate (8-oxo-..
- Ogawa T, Ueda Y, Yoshimura K, Shigeoka S. Comprehensive analysis of cytosolic Nudix hydrolases in Arabidopsis thaliana. J Biol Chem. 2005;280:25277-83 pubmed..Here, we demonstrated the comprehensive analysis of nine types of cytosolic AtNUDT proteins (AtNUDT1, -2, -4, -5, -6, -7, -9, -10, and -11)...
- Klaus S, Wegkamp A, Sybesma W, Hugenholtz J, Gregory J, Hanson A. A nudix enzyme removes pyrophosphate from dihydroneopterin triphosphate in the folate synthesis pathway of bacteria and plants. J Biol Chem. 2005;280:5274-80 pubmed..coli and shown to have Mg(2+)-dependent DHNTP pyrophosphohydrolase activity. This protein (AtNUDT1) was reported previously to have NADH pyrophosphatase activity in the presence of 5 mM Mn(2+) (Dobrzanska, M...
- Dobrzanska M, Szurmak B, Wyslouch Cieszynska A, Kraszewska E. Cloning and characterization of the first member of the Nudix family from Arabidopsis thaliana. J Biol Chem. 2002;277:50482-6 pubmed..The deduced amino acid sequence of AtNUDT1 contains 147 amino acids. The recombinant AtNUDT1 was expressed in Escherichia coli and purified...