PEN3

Summary

Gene Symbol: PEN3
Description: ABC-2 and Plant PDR ABC-type transporter family protein
Alias: ABCG36, ARABIDOPSIS PLEIOTROPIC DRUG RESISTANCE 8, ARABIDOPSIS THALIANA ATP-BINDING CASSETTE G36, ATABCG36, ATP-BINDING CASSETTE G36, ATP-binding cassette G36, ATPDR8, Arabidopsis thaliana ATP-binding cassette G36, F23H11.19, F23H11_19, PDR8, PENETRATION 3, PLEIOTROPIC DRUG RESISTANCE 8
Species: thale cress

Top Publications

  1. pmc Arabidopsis PIS1 encodes the ABCG37 transporter of auxinic compounds including the auxin precursor indole-3-butyric acid
    Kamil Ruzicka
    Department of Plant Systems Biology, Flanders Institute for Biotechnology, Ghent University, 9052 Ghent, Belgium
    Proc Natl Acad Sci U S A 107:10749-53. 2010
  2. pmc Mutant Allele-Specific Uncoupling of PENETRATION3 Functions Reveals Engagement of the ATP-Binding Cassette Transporter in Distinct Tryptophan Metabolic Pathways
    Xunli Lu
    Department of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, 50829 Cologne, Germany X L, J Di, M P B, P B, P S L Institute of Bioorganic Chemistry, Polish Academy of Sciences, 61 704 Poznan, Poland M P B, P B Centro de Biotecnología y Genómica de Plantas, Universidad Politecnica de Madrid, 28223 Madrid, Spain A M Research Groups on Biosynthesis Nuclear Magnetic Resonance B S and Mass Spectrometry Proteomics A S, J Do, Max Planck Institute for Chemical Ecology, 07745 Jena, Germany andDepartment of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tuebingen, Germany K S, D W
    Plant Physiol 168:814-27. 2015
  3. pmc Perception of conserved pathogen elicitors at the plasma membrane leads to relocalization of the Arabidopsis PEN3 transporter
    William Underwood
    Energy Biosciences Institute and Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA
    Proc Natl Acad Sci U S A 110:12492-7. 2013
  4. doi Induction and suppression of PEN3 focal accumulation during Pseudomonas syringae pv. tomato DC3000 infection of Arabidopsis
    Xiu Fang Xin
    Department of Plant Biology, Michigan State University, East Lansing, MI, USA
    Mol Plant Microbe Interact 26:861-7. 2013
  5. ncbi Loss of AtPDR8, a plasma membrane ABC transporter of Arabidopsis thaliana, causes hypersensitive cell death upon pathogen infection
    Yoshihiro Kobae
    Laboratory of Cell Dynamics, Graduate School of Bioagricultural Sciences, Nagoya University, Japan
    Plant Cell Physiol 47:309-18. 2006
  6. pmc Arabidopsis PEN3/PDR8, an ATP binding cassette transporter, contributes to nonhost resistance to inappropriate pathogens that enter by direct penetration
    Monica Stein
    Carnegie Institution, Department of Plant Biology, Stanford, California, 94305, USA
    Plant Cell 18:731-46. 2006
  7. ncbi Organization and function of the plant pleiotropic drug resistance ABC transporter family
    Jerome Crouzet
    Unite de Biochimie Physiologique, Institut des Sciences de la Vie, Univerisity of Louvain, Croix du Sud 5 15, 1348 Louvain la Neuve, Belgium
    FEBS Lett 580:1123-30. 2006
  8. ncbi Conserved requirement for a plant host cell protein in powdery mildew pathogenesis
    Chiara Consonni
    Max Planck Institute for Plant Breeding Research, Department of Plant Microbe Interactions, Carl von Linne Weg 10, D 50829 Köln, Germany
    Nat Genet 38:716-20. 2006
  9. ncbi The ABC transporter AtPDR8 is a cadmium extrusion pump conferring heavy metal resistance
    Do Young Kim
    POSTECH UZH Cooperative Laboratory, Division of Molecular Life Sciences, Pohang University of Science and Technology, Pohang 790 784, Korea
    Plant J 50:207-18. 2007
  10. doi Characterization of nonhost resistance of Arabidopsis to the Asian soybean rust
    Marco Loehrer
    Department of Plant Physiology, RWTH Aachen University, D 52056 Aachen, Germany
    Mol Plant Microbe Interact 21:1421-30. 2008

Detail Information

Publications13

  1. pmc Arabidopsis PIS1 encodes the ABCG37 transporter of auxinic compounds including the auxin precursor indole-3-butyric acid
    Kamil Ruzicka
    Department of Plant Systems Biology, Flanders Institute for Biotechnology, Ghent University, 9052 Ghent, Belgium
    Proc Natl Acad Sci U S A 107:10749-53. 2010
    ..ABCG37 and its homolog ABCG36 act redundantly at outermost root plasma membranes and, unlike established IAA transporters from the PIN and ABCB ..
  2. pmc Mutant Allele-Specific Uncoupling of PENETRATION3 Functions Reveals Engagement of the ATP-Binding Cassette Transporter in Distinct Tryptophan Metabolic Pathways
    Xunli Lu
    Department of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, 50829 Cologne, Germany X L, J Di, M P B, P B, P S L Institute of Bioorganic Chemistry, Polish Academy of Sciences, 61 704 Poznan, Poland M P B, P B Centro de Biotecnología y Genómica de Plantas, Universidad Politecnica de Madrid, 28223 Madrid, Spain A M Research Groups on Biosynthesis Nuclear Magnetic Resonance B S and Mass Spectrometry Proteomics A S, J Do, Max Planck Institute for Chemical Ecology, 07745 Jena, Germany andDepartment of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tuebingen, Germany K S, D W
    Plant Physiol 168:814-27. 2015
    ..b>PEN3 encodes a plasma membrane-resident pleiotropic drug resistance-type ATP-binding cassette transporter and is thought ..
  3. pmc Perception of conserved pathogen elicitors at the plasma membrane leads to relocalization of the Arabidopsis PEN3 transporter
    William Underwood
    Energy Biosciences Institute and Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA
    Proc Natl Acad Sci U S A 110:12492-7. 2013
    The Arabidopsis penetration resistance 3 (PEN3) ATP binding cassette transporter participates in nonhost resistance to fungal and oomycete pathogens and is required for full penetration resistance to the barley powdery mildew Blumeria ..
  4. doi Induction and suppression of PEN3 focal accumulation during Pseudomonas syringae pv. tomato DC3000 infection of Arabidopsis
    Xiu Fang Xin
    Department of Plant Biology, Michigan State University, East Lansing, MI, USA
    Mol Plant Microbe Interact 26:861-7. 2013
    ..b>AtPDR8, also called PEN3, is required for penetration resistance of Arabidopsis to nonadapted powdery mildew fungi...
  5. ncbi Loss of AtPDR8, a plasma membrane ABC transporter of Arabidopsis thaliana, causes hypersensitive cell death upon pathogen infection
    Yoshihiro Kobae
    Laboratory of Cell Dynamics, Graduate School of Bioagricultural Sciences, Nagoya University, Japan
    Plant Cell Physiol 47:309-18. 2006
    Plants contain a large number of ATP-binding cassette (ABC) transporters belonging to different subclasses. AtPDR8 is the only member of the pleiotropic drug resistance (PDR) ABC transporter subclass in Arabidopsis that is constitutively ..
  6. pmc Arabidopsis PEN3/PDR8, an ATP binding cassette transporter, contributes to nonhost resistance to inappropriate pathogens that enter by direct penetration
    Monica Stein
    Carnegie Institution, Department of Plant Biology, Stanford, California, 94305, USA
    Plant Cell 18:731-46. 2006
    ..Screening for Arabidopsis mutants deficient in resistance to barley powdery mildew identified PENETRATION3 (PEN3). pen3 plants permitted both increased invasion into epidermal cells and initiation of hyphae by B. g...
  7. ncbi Organization and function of the plant pleiotropic drug resistance ABC transporter family
    Jerome Crouzet
    Unite de Biochimie Physiologique, Institut des Sciences de la Vie, Univerisity of Louvain, Croix du Sud 5 15, 1348 Louvain la Neuve, Belgium
    FEBS Lett 580:1123-30. 2006
    ..Only a single subfamily II member has been characterized. Induction of its expression by iron deficiency suggests its involvement in iron deficiency stress, thus, enlightening a new physiological role for a PDR gene...
  8. ncbi Conserved requirement for a plant host cell protein in powdery mildew pathogenesis
    Chiara Consonni
    Max Planck Institute for Plant Breeding Research, Department of Plant Microbe Interactions, Carl von Linne Weg 10, D 50829 Köln, Germany
    Nat Genet 38:716-20. 2006
    ....
  9. ncbi The ABC transporter AtPDR8 is a cadmium extrusion pump conferring heavy metal resistance
    Do Young Kim
    POSTECH UZH Cooperative Laboratory, Division of Molecular Life Sciences, Pohang University of Science and Technology, Pohang 790 784, Korea
    Plant J 50:207-18. 2007
    Cadmium (Cd) and lead (Pb) are widespread pollutants that are toxic to plant growth. The expression of AtPDR8 was upregulated in cadmium- or lead-treated Arabidopsis thaliana...
  10. doi Characterization of nonhost resistance of Arabidopsis to the Asian soybean rust
    Marco Loehrer
    Department of Plant Physiology, RWTH Aachen University, D 52056 Aachen, Germany
    Mol Plant Microbe Interact 21:1421-30. 2008
    ..Double mutants affected in either jasmonic acid or salicylic acid signaling in the pen3-1 background revealed the involvement of both pathways in nonhost resistance (NHR) of Arabidopsis to P. pachyrhizi...
  11. pmc Glucosinolate metabolites required for an Arabidopsis innate immune response
    Nicole K Clay
    Department of Genetics, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA
    Science 323:95-101. 2009
    ..Two genes, PEN2 and PEN3, are also necessary for resistance to pathogens and are required for both callose deposition and glucosinolate ..
  12. pmc The Arabidopsis PLEIOTROPIC DRUG RESISTANCE8/ABCG36 ATP binding cassette transporter modulates sensitivity to the auxin precursor indole-3-butyric acid
    Lucia C Strader
    Department of Biochemistry and Cell Biology, Rice University, Houston, Texas 77005, USA
    Plant Cell 21:1992-2007. 2009
    ..This mutant is defective in PLEIOTROPIC DRUG RESISTANCE8 (PDR8)/PENETRATION3/ABCG36, a plasma membrane-localized ATP binding cassette transporter that has established roles in pathogen responses and ..
  13. doi Overexpression of AtABCG36 improves drought and salt stress resistance in Arabidopsis
    Do Young Kim
    POSTECH UZH Cooperative Laboratory, Division of Molecular Life Sciences, Pohang University of Science and Technology, Pohang 790 784, Korea
    Physiol Plant 139:170-80. 2010
    ..longer than 5 weeks, transgenic Arabidopsis plants that overexpress an ATP-binding cassette (ABC) transporter, AtABCG36/AtPDR8, produced higher shoot biomass and less chlorotic leaves than the wild-type...