PHYB

Summary

Gene Symbol: PHYB
Description: phytochrome B
Alias: HY3, MSF3.17, MSF3_17, OOP1, OUT OF PHASE 1, PHYTOCHROME B, phytochrome B
Species: thale cress

Top Publications

  1. ncbi PIF3, a phytochrome-interacting factor necessary for normal photoinduced signal transduction, is a novel basic helix-loop-helix protein
    M Ni
    Department of Plant and Microbial Biology, University of California, Berkeley 94720, USA
    Cell 95:657-67. 1998
  2. ncbi The AT-hook-containing proteins SOB3/AHL29 and ESC/AHL27 are negative modulators of hypocotyl growth in Arabidopsis
    Ian H Street
    Department of Biology, Washington University, St Louis, MO 63130, USA
    Plant J 54:1-14. 2008
  3. pmc Ecological modulation of plant defense via phytochrome control of jasmonate sensitivity
    Javier E Moreno
    IFEVA, Consejo Nacional de Investigaciones Cientificas y Tecnicas, and Universidad de Buenos Aires, Avenida San Martín 4453 C1417DSE Buenos Aires, Argentina
    Proc Natl Acad Sci U S A 106:4935-40. 2009
  4. doi phytochrome B and PIF4 regulate stomatal development in response to light quantity
    Stuart A Casson
    School of Biological Sciences, University of Bristol, Woodland Road, Bristol, UK
    Curr Biol 19:229-34. 2009
  5. ncbi The roles of phytochromes in elongation and gravitropism of roots
    Melanie J Correll
    Department of Botany, Miami University, Oxford, OH 45056, USA
    Plant Cell Physiol 46:317-23. 2005
  6. ncbi Regulation of phytochrome B nuclear localization through light-dependent unmasking of nuclear-localization signals
    Meng Chen
    Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, California 92037, USA
    Curr Biol 15:637-42. 2005
  7. ncbi phyA dominates in transduction of red-light signals to rapidly responding genes at the initiation of Arabidopsis seedling de-etiolation
    James M Tepperman
    Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA
    Plant J 48:728-42. 2006
  8. ncbi Functional cross-talk between two-component and phytochrome B signal transduction in Arabidopsis
    Virtudes Mira-Rodado
    Zentrum für Molekularbiologie der Pflanzen Pflanzenphysiologie, Universitat Tubingen, Auf der Morgenstelle 1, D 72076, Tubingen, Germany
    J Exp Bot 58:2595-607. 2007
  9. pmc Light-independent phytochrome signaling mediated by dominant GAF domain tyrosine mutants of Arabidopsis phytochromes in transgenic plants
    Yi shin Su
    Section of Molecular and Cellular Biology, University of California, Davis, California 95616, USA
    Plant Cell 19:2124-39. 2007
  10. pmc Phytochrome induces rapid PIF5 phosphorylation and degradation in response to red-light activation
    Yu Shen
    Department of Plant and Microbial Biology, University of California, Berkeley, California 94720, USA
    Plant Physiol 145:1043-51. 2007

Scientific Experts

  • Robert A Sharrock
  • Peter Quail
  • Stuart A Casson
  • Stefan Kircher
  • Scott A Finlayson
  • Darron R Luesse
  • Ferenc Nagy
  • Eberhard Schafer
  • Akira Nagatani
  • Enamul Huq
  • Yoshito Oka
  • Joanne Chory
  • Tomonao Matsushita
  • Jeong Il Kim
  • Hiromasa Shikata
  • Eva Adam
  • Yu Shen
  • Rajnish Khanna
  • Javier E Moreno
  • Andras Viczian
  • Alicia Castillon
  • Motomu Endo
  • Dong Ho Shin
  • Tim Kunkel
  • Bong Kwan Phee
  • Mercedes M Keller
  • Carlos L Ballaré
  • Laszlo Kozma-Bognar
  • Shogo Ito
  • Séverine Lorrain
  • Eunae Park
  • Giltsu Choi
  • Melanie J Correll
  • Hui Shen
  • Seong Hee Bhoo
  • Tae Ryong Hahn
  • Jong Seong Jeon
  • Christian Fankhauser
  • Eva Kevei
  • Elise A Kikis
  • Yong Sic Hwang
  • Meng Chen
  • Pill Soon Song
  • Ari Sadanandom
  • Nobuyoshi Mochizuki
  • Ana Lazaro
  • Melisa Leone
  • Zenglin Zhang
  • Bassem Al-Sady
  • Chentao Lin
  • Yihai Wang
  • John Z Kiss
  • Kazumasa Nito
  • Mátyás Medzihradszky
  • Weimin Ni
  • Junrui Zhang
  • Eve Marie Josse
  • Aurora Piñas Fernández
  • Ken Matsuoka
  • Carina Verónica González
  • Rafaelo M Galvão
  • Moeko Nakashima
  • Zsuzsanna Mérai
  • Sam Geun Kong
  • Diana Bauer
  • Julia Foreman
  • Keunhwa Kim
  • Kana Miyata
  • Qingyun Bu
  • Volker Bischoff
  • Andrea Palágyi
  • In Cheol Jang
  • Fang Fang Wang
  • Stefano Gabriele
  • Julia Rausenberger
  • Péter Gyula
  • J Clark Lagarias
  • Julin N Maloof
  • Ling Zhu
  • Takashi Araki
  • Yun Jeong Han
  • Hernan E Boccalandro
  • Federico Tessadori
  • Man Ho Cho
  • Ted Clack
  • Tsuyoshi Mizoguchi
  • Jihye Yoo
  • Nam Hai Chua
  • Daniele L Filiault
  • Ian H Street

Detail Information

Publications94

  1. ncbi PIF3, a phytochrome-interacting factor necessary for normal photoinduced signal transduction, is a novel basic helix-loop-helix protein
    M Ni
    Department of Plant and Microbial Biology, University of California, Berkeley 94720, USA
    Cell 95:657-67. 1998
    ..PIF3 binds to wild-type C-terminal domains of both phyA and phyB, but less strongly to signaling-defective, missense mutant-containing domains...
  2. ncbi The AT-hook-containing proteins SOB3/AHL29 and ESC/AHL27 are negative modulators of hypocotyl growth in Arabidopsis
    Ian H Street
    Department of Biology, Washington University, St Louis, MO 63130, USA
    Plant J 54:1-14. 2008
    ..protein, was identified from an activation-tagging screen for suppressors of the long-hypocotyl phenotype of a weak phyB allele, phyB-4...
  3. pmc Ecological modulation of plant defense via phytochrome control of jasmonate sensitivity
    Javier E Moreno
    IFEVA, Consejo Nacional de Investigaciones Cientificas y Tecnicas, and Universidad de Buenos Aires, Avenida San Martín 4453 C1417DSE Buenos Aires, Argentina
    Proc Natl Acad Sci U S A 106:4935-40. 2009
    ..We conclude that the plant modulates its investment in defense as a function of the perceived risk of competition, and that this modulation is effected by phytochrome via selective desensitization to jasmonates...
  4. doi phytochrome B and PIF4 regulate stomatal development in response to light quantity
    Stuart A Casson
    School of Biological Sciences, University of Bristol, Woodland Road, Bristol, UK
    Curr Biol 19:229-34. 2009
    ..By using a genetic approach, we demonstrate that this response is dominated by phytochrome B and also identify a role for the transcription factor, PHYTOCHROME-INTERACTING FACTOR 4 (PIF4) [7]...
  5. ncbi The roles of phytochromes in elongation and gravitropism of roots
    Melanie J Correll
    Department of Botany, Miami University, Oxford, OH 45056, USA
    Plant Cell Physiol 46:317-23. 2005
    ..The importance of phytochromes A and B (phyA and phyB) in these red light responses has been established through studies using phy mutants...
  6. ncbi Regulation of phytochrome B nuclear localization through light-dependent unmasking of nuclear-localization signals
    Meng Chen
    Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, California 92037, USA
    Curr Biol 15:637-42. 2005
    ..Using Arabidopsis phyB as a model, we demonstrate that the C-terminal PAS-related domain (PRD) is both necessary and sufficient for phyB ..
  7. ncbi phyA dominates in transduction of red-light signals to rapidly responding genes at the initiation of Arabidopsis seedling de-etiolation
    James M Tepperman
    Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA
    Plant J 48:728-42. 2006
    ..profiling showed that one or more of the five-membered phytochrome (phy) family of Arabidopsis, other than phyB, is predominantly responsible for transducing the Rc signals to light-responsive genes...
  8. ncbi Functional cross-talk between two-component and phytochrome B signal transduction in Arabidopsis
    Virtudes Mira-Rodado
    Zentrum für Molekularbiologie der Pflanzen Pflanzenphysiologie, Universitat Tubingen, Auf der Morgenstelle 1, D 72076, Tubingen, Germany
    J Exp Bot 58:2595-607. 2007
    ..ARR4 interacts with the N-terminus of the red/far-red light photoreceptor phytochrome B (phyB) and functions as a modulator of photomorphogenesis...
  9. pmc Light-independent phytochrome signaling mediated by dominant GAF domain tyrosine mutants of Arabidopsis phytochromes in transgenic plants
    Yi shin Su
    Section of Molecular and Cellular Biology, University of California, Davis, California 95616, USA
    Plant Cell 19:2124-39. 2007
    ..Through expression of profluorescent, photoinsensitive Tyr-to-His mutant alleles of Arabidopsis thaliana phytochrome B (PHYB(Y276H)) and Arabidopsis phytochrome A (PHYA(Y242H)) in transgenic Arabidopsis plants, we demonstrate ..
  10. pmc Phytochrome induces rapid PIF5 phosphorylation and degradation in response to red-light activation
    Yu Shen
    Department of Plant and Microbial Biology, University of California, Berkeley, California 94720, USA
    Plant Physiol 145:1043-51. 2007
    ..that the photoactivated phy molecule acts within 60 s to induce this phosphorylation of PIF5, and that phyA and phyB redundantly dominate this process, with phyD playing an apparently minor role...
  11. ncbi Phytochrome-mediated inhibition of shade avoidance involves degradation of growth-promoting bHLH transcription factors
    Séverine Lorrain
    Center for Integrative Genomics, University of Lausanne, Genopode Building, CH 1015 Lausanne, Switzerland
    Plant J 53:312-23. 2008
    ..PIFs contain an active phytochrome binding (APB) domain that mediates their interaction with light-activated phytochrome B (phyB)...
  12. pmc The basic helix-loop-helix transcription factor PIF5 acts on ethylene biosynthesis and phytochrome signaling by distinct mechanisms
    Rajnish Khanna
    Department of Plant and Microbial Biology, University of California, Berkeley, California 94720, USA
    Plant Cell 19:3915-29. 2007
    ..PIF5), a basic helix-loop-helix transcription factor, interacts specifically with the photoactivated form of phytochrome B (phyB)...
  13. pmc The Arabidopsis phytochrome-interacting factor PIF7, together with PIF3 and PIF4, regulates responses to prolonged red light by modulating phyB levels
    Pablo Leivar
    Department of Plant and Microbial Biology, University of California, Berkeley, California 94720, USA
    Plant Cell 20:337-52. 2008
    ..interacting factor (PIF), designated PIF7, interacts specifically with the far-red light-absorbing Pfr form of phyB through a conserved domain called the active phyB binding motif...
  14. pmc Amino acid polymorphisms in Arabidopsis phytochrome B cause differential responses to light
    Daniele L Filiault
    Section of Plant Biology, College of Biological Sciences, University of California, One Shields Avenue, Davis, CA 95616, USA
    Proc Natl Acad Sci U S A 105:3157-62. 2008
    ..In Arabidopsis thaliana, phytochrome B (PHYB) is the dominant photoreceptor for red light and plays a major role in white light...
  15. pmc Light-induced phosphorylation and degradation of the negative regulator PHYTOCHROME-INTERACTING FACTOR1 from Arabidopsis depend upon its direct physical interactions with photoactivated phytochromes
    Hui Shen
    Section of Molecular Cell and Developmental Biology and Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas 78712, USA
    Plant Cell 20:1586-602. 2008
    ..phyA plays a dominant role in regulating the degradation of PIF1 following initial light exposure, while phyB and phyD and possibly other phys also influence PIF1 degradation after prolonged illumination...
  16. pmc Mutant screen distinguishes between residues necessary for light-signal perception and signal transfer by phytochrome B
    Yoshito Oka
    Department of Biology, Graduate School of Science, Kyoto University, Kyoto, Japan
    PLoS Genet 4:e1000158. 2008
    ..The N-terminal 651-amino acid domain of phyB (N651), which binds an open tetrapyrrole chromophore, acts to perceive and transduce regulatory light signals in ..
  17. pmc Blue light induces degradation of the negative regulator phytochrome interacting factor 1 to promote photomorphogenic development of Arabidopsis seedlings
    Alicia Castillon
    University of Texas, Austin, Texas 78712, USA
    Genetics 182:161-71. 2009
    ..PIF1 interacted with phyA and phyB in a blue light-dependent manner, and the interactions with phys are necessary for the blue light-induced ..
  18. pmc Phytochrome B enhances photosynthesis at the expense of water-use efficiency in Arabidopsis
    Hernan E Boccalandro
    IFEVA, Facultad de Agronomia, Universidad de Buenos Aires, and Consejo Nacional de Investigaciones Cientificas y Tecnicas, 1417 Buenos Aires, Argentina
    Plant Physiol 150:1083-92. 2009
    ..High red to far-red ratios increase the proportion of phytochrome B (phyB) in its active form and the phyB mutant exhibited a constitutively low stomata density...
  19. pmc Phytochrome B and histone deacetylase 6 control light-induced chromatin compaction in Arabidopsis thaliana
    Federico Tessadori
    Nuclear Organization Group, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, The Netherlands
    PLoS Genet 5:e1000638. 2009
    ..approach, combining Quantitative Trait Locus (QTL) mapping and microscopic examination, pointed at PHYTOCHROME-B (PHYB) and HISTONE DEACETYLASE-6 (HDA6) as positive regulators of light-controlled chromatin compaction...
  20. doi Phytochrome B is involved in mediating red light-induced stomatal opening in Arabidopsis thaliana
    Fang Fang Wang
    National Key Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 300 Fenglin Road, Shanghai, China
    Mol Plant 3:246-59. 2010
    ..However, whether phytochrome B (phyB) is involved in red light regulation of stomatal opening remains largely unclear...
  21. pmc An integrative model for phytochrome B mediated photomorphogenesis: from protein dynamics to physiology
    Julia Rausenberger
    Centre for Biological Systems Analysis, University of Freiburg, Freiburg, Germany
    PLoS ONE 5:e10721. 2010
    ..To monitor the intensity and spectral composition of the ambient light environment, plants have evolved multiple photoreceptors, including the red/far-red light-sensing phytochromes...
  22. pmc Functional analysis of amino-terminal domains of the photoreceptor phytochrome B
    Andrea Palágyi
    Institute of Plant Biology, Biological Research Centre of the Hungarian Academy of Sciences, H 6726 Szeged, Hungary
    Plant Physiol 153:1834-45. 2010
    ..b>Phytochrome B (PHYB) is the major red/far-red light-absorbing phytochrome receptor in light-grown plants...
  23. pmc A small GTPase activator protein interacts with cytoplasmic phytochromes in regulating root development
    Dong Ho Shin
    Graduate School of Biotechnology and Plant Metabolism Research Center, Kyung Hee University, Yongin 446 701
    J Biol Chem 285:32151-9. 2010
    ..In addition, both PIRF1 overexpression mutants (PIRF1-OX) and phytochrome-null mutants (phyA-211 and phyB-9) showed retarded root elongation and irregular root hair formation, suggesting that PIRF1 is a negative regulator ..
  24. pmc Arabidopsis PHYTOCHROME INTERACTING FACTOR proteins promote phytochrome B polyubiquitination by COP1 E3 ligase in the nucleus
    In Cheol Jang
    Laboratory of Plant Molecular Biology, The Rockefeller University, New York, New York 10065, USA
    Plant Cell 22:2370-83. 2010
    Many plant photoresponses from germination to shade avoidance are mediated by phytochrome B (phyB)...
  25. pmc Photoactivated phytochromes interact with HEMERA and promote its accumulation to establish photomorphogenesis in Arabidopsis
    Rafaelo M Galvão
    Department of Biology, Duke University, Durham, North Carolina 27708, USA
    Genes Dev 26:1851-63. 2012
    ..We recently identified a key phytochrome signaling component, HEMERA (HMR), that is essential for both phytochrome B (phyB) localization to photobodies and PIF degradation...
  26. pmc Phosphorylation of phytochrome B inhibits light-induced signaling via accelerated dark reversion in Arabidopsis
    Mátyás Medzihradszky
    Faculty of Biology, University of Freiburg, D 79104, Freiburg Germany
    Plant Cell 25:535-44. 2013
    The photoreceptor phytochrome B (phyB) interconverts between the biologically active Pfr (λmax = 730 nm) and inactive Pr (λmax = 660 nm) forms in a red/far-red-dependent fashion and regulates, as molecular switch, many aspects of light-..
  27. pmc PIL5, a phytochrome-interacting basic helix-loop-helix protein, is a key negative regulator of seed germination in Arabidopsis thaliana
    Eunkyoo Oh
    Department of Biological Sciences, KAIST, Daejeon 305 701, Korea
    Plant Cell 16:3045-58. 2004
    ..PIL5 preferentially interacts with the Pfr forms of Phytochrome A (PhyA) and Phytochrome B (PhyB)...
  28. ncbi Direct targeting of light signals to a promoter element-bound transcription factor
    J F Martínez-García
    Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA
    Science 288:859-63. 2000
    ..binds specifically to a G-box DNA-sequence motif present in various light-regulated gene promoters, and that phytochrome B binds reversibly to G-box-bound PIF3 specifically upon light-triggered conversion of the photoreceptor to its ..
  29. ncbi Functional interaction of phytochrome B and cryptochrome 2
    P Mas
    Department of Cell Biology and National Science Foundation Center for Biological Timing, The Scripps Research Institute, La Jolla, California 92037, USA
    Nature 408:207-11. 2000
    ..Here we show the genetic interaction that occurs between the Arabidopsis photoreceptors phyB and cry2 in the control of flowering time, hypocotyl elongation and circadian period by the clock...
  30. ncbi Binding of phytochrome B to its nuclear signalling partner PIF3 is reversibly induced by light
    M Ni
    Department of Plant and Microbial Biology, University of California, Berkeley 94720, USA
    Nature 400:781-4. 1999
    ..Here we show that full-length photoactive phytochrome B binds PIF3 in vitro only upon light-induced conversion to its active form, and that photoconversion back to ..
  31. ncbi Interaction of the response regulator ARR4 with phytochrome B in modulating red light signaling
    U Sweere
    Institut für Biologie II Botanik, Universitat Freiburg, Schanzlestrasse 1, 79104 Freiburg, Germany
    Science 294:1108-11. 2001
    The Arabidopsis thaliana response regulator 4, expressed in response to phytochrome B action, specifically interacts with the extreme amino-terminus of the photoreceptor...
  32. ncbi Phytochrome-interacting factor 1 is a critical bHLH regulator of chlorophyll biosynthesis
    Enamul Huq
    Section of Molecular Cell and Developmental Biology and Institute of Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA
    Science 305:1937-41. 2004
    ....
  33. pmc The signaling mechanism of Arabidopsis CRY1 involves direct interaction with COP1
    H Q Yang
    Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6018, USA
    Plant Cell 13:2573-87. 2001
    ..An interaction also was observed between the C-terminal domain of Arabidopsis phytochrome B and COP1, suggesting that phytochrome signaling also proceeds, at least in part, through direct interaction ..
  34. pmc PIF4, a phytochrome-interacting bHLH factor, functions as a negative regulator of phytochrome B signaling in Arabidopsis
    Enamul Huq
    Department of Plant and Microbial Biology, University of California, Berkeley 94720, USA
    EMBO J 21:2441-50. 2002
    ..in srl2phyB, but not srl2phyA, double mutants, indicating that this locus functions selectively and negatively in phyB signaling...
  35. pmc Light-dependent translocation of a phytochrome B-GFP fusion protein to the nucleus in transgenic Arabidopsis
    R Yamaguchi
    Department of Botany, Graduate School of Science, Kyoto University, Kyoto 606 8502, Japan
    J Cell Biol 145:437-45. 1999
    ..nuclear localization signal may reside within the COOH-terminal region of a major member of the family, phytochrome B (phyB) (Sakamoto, K., and A. Nagatani. 1996. Plant J. 10:859-868)...
  36. pmc Constitutive photomorphogenesis 1 and multiple photoreceptors control degradation of phytochrome interacting factor 3, a transcription factor required for light signaling in Arabidopsis
    Diana Bauer
    Biologie II Institut für Botanik, University of Freiburg, Freiburg, Germany D 79104
    Plant Cell 16:1433-45. 2004
    ..induces nuclear import of the plant photoreceptors phytochrome, promotes interaction of phytochrome A (phyA) and phyB with transcription factors including phytochrome interacting factor 3 (PIF3), and is thought to trigger a ..
  37. pmc HFR1 encodes an atypical bHLH protein that acts in phytochrome A signal transduction
    C D Fairchild
    Department of Plant and Microbial Biology, University of California, Berkeley, California 94720, USA
    Genes Dev 14:2377-91. 2000
    ..In contrast to PIF3, a related bHLH protein previously shown to bind phyB, HFR1 did not bind either phyA or B...
  38. ncbi Roles for the N- and C-terminal domains of phytochrome B in interactions between phytochrome B and cryptochrome signaling cascades
    Takeshi Usami
    Department of Botany, Graduate School of Science, Kyoto University, Sakyo ku, Kyoto, 606 8502, Japan
    Plant Cell Physiol 48:424-33. 2007
    ..In the present study, we investigated the functions of the N- and C-terminal domains of phytochrome B (phyB) in the interactions between phyB and cryptochrome signaling cascades...
  39. pmc A novel molecular recognition motif necessary for targeting photoactivated phytochrome signaling to specific basic helix-loop-helix transcription factors
    Rajnish Khanna
    Department of Plant and Microbial Biology, University of California, Berkeley, California 94720, USA
    Plant Cell 16:3033-44. 2004
    ..designated PHYTOCHROME-INTERACTING FACTOR5 (PIF5) and PIF6, which interact specifically with the Pfr form of phyB. These two factors cluster tightly with PIF3 and two other phy-interacting bHLH proteins in a phylogenetic ..
  40. pmc Phytochrome B in the mesophyll delays flowering by suppressing FLOWERING LOCUS T expression in Arabidopsis vascular bundles
    Motomu Endo
    Laboratory of Plant Physiology, Graduate School of Science, Kyoto University, Kitashirakawa Oiwake cho, Sakyo ku, Kyoto 606 8502, Japan
    Plant Cell 17:1941-52. 2005
    ..b>Phytochrome B (phyB) acts as a photoreceptor for this response...
  41. pmc Tyrosine phosphorylation regulates the activity of phytochrome photoreceptors
    Kazumasa Nito
    Plant Biology Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
    Cell Rep 3:1970-9. 2013
    ..We examined whether phytochrome is phosphorylated in response to light, and we report that phytochrome B (phyB)'s N terminus contains a region with a number of phosphoserines, threonines, and tyrosines...
  42. pmc Red Light-Mediated Degradation of CONSTANS by the E3 Ubiquitin Ligase HOS1 Regulates Photoperiodic Flowering in Arabidopsis
    Ana Lazaro
    Centro de Biotecnología y Genómica de Plantas, INIA UPM, Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria, 28223 Madrid, Spain
    Plant Cell 27:2437-54. 2015
    ..Our results show that phytochrome B (phyB) is able to regulate flowering time, acting in the phloem companion cells, as previously described for ..
  43. pmc SUMOylation of phytochrome-B negatively regulates light-induced signaling in Arabidopsis thaliana
    Ari Sadanandom
    School of Biological and Biomedical Sciences, University of Durham, Durham DH1 3LE, United Kingdom
    Proc Natl Acad Sci U S A 112:11108-13. 2015
    The red/far red light absorbing photoreceptor phytochrome-B (phyB) cycles between the biologically inactive (Pr, λmax, 660 nm) and active (Pfr; λmax, 730 nm) forms and functions as a light quality and quantity controlled switch to ..
  44. doi To grow or defend? Low red : far-red ratios reduce jasmonate sensitivity in Arabidopsis seedlings by promoting DELLA degradation and increasing JAZ10 stability
    Melisa Leone
    IFEVA, Consejo Nacional de Investigaciones Científicas y Técnicas Universidad de Buenos Aires, C1417DSE, Buenos Aires, Argentina
    New Phytol 204:355-67. 2014
    ..We showed that a quintuple della mutant and a phyB mutant were insensitive to jasmonate for several physiological readouts...
  45. pmc Residues clustered in the light-sensing knot of phytochrome B are necessary for conformer-specific binding to signaling partner PIF3
    Elise A Kikis
    Department of Plant and Microbial Biology, University of California Berkeley, Berkeley, California, United States of America
    PLoS Genet 5:e1000352. 2009
    ..Interacting Factor 3 (PIF3), interacts specifically with the photoactivated, Pfr, form of Arabidopsis phytochrome B (phyB)...
  46. pmc Shedding light on flower development: phytochrome B regulates gynoecium formation in association with the transcription factor SPATULA
    Julia Foreman
    School of Biological Sciences, University of Edinburgh, Edinburgh, Scotland, UK
    Plant Signal Behav 6:471-6. 2011
    ..Here, we show that the spt phenotype is rescued by the removal of phytochrome B, and discuss how light signaling may control flower development.
  47. doi CONSTANS-LIKE 7 (COL7) is involved in phytochrome B (phyB)-mediated light-quality regulation of auxin homeostasis
    Zenglin Zhang
    Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China
    Mol Plant 7:1429-40. 2014
    Arabidopsis phytochrome B (phyB) is the major photoreceptor that senses the ratio of red to far-red light (R:FR) to regulate the shade-avoidance response (SAR)...
  48. pmc Suppression of late-flowering and semi-dwarf phenotypes in the Arabidopsis clock mutant lhy-12;cca1-101 by phyB under continuous light
    Kana Miyata
    Gene Research Center, University of Tsukuba, Tsukuba, Ibaraki, Japan
    Plant Signal Behav 6:1162-71. 2011
    ..We identified two novel mutations, a dominant (del1) and a recessive (phyB-2511) allele of phyB...
  49. pmc Multisite light-induced phosphorylation of the transcription factor PIF3 is necessary for both its rapid degradation and concomitant negative feedback modulation of photoreceptor phyB levels in Arabidopsis
    Weimin Ni
    Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA
    Plant Cell 25:2679-98. 2013
    ..In addition, we show that phyB-induced PIF3 phosphorylation is also required for the known negative feedback modulation of phyB levels in ..
  50. pmc PHYTOCHROME-DEPENDENT LATE-FLOWERING accelerates flowering through physical interactions with phytochrome B and CONSTANS
    Motomu Endo
    Graduate School of Biostudies, Kyoto University, Kyoto 606 8501, Japan
    Proc Natl Acad Sci U S A 110:18017-22. 2013
    ..In Arabidopsis, phytochrome B (phyB); phyA; cryptochrome 2; and flavin-binding, KELCH repeat, F-BOX 1 are major photoreceptors that regulate ..
  51. doi Phytochrome regulation of cellulose synthesis in Arabidopsis
    Volker Bischoff
    Institut Jean Pierre Bourgin, UMR1318 INRA AgroParisTech, 78026 Versailles, France
    Curr Biol 21:1822-7. 2011
    ..Here we show a role for the red/far-red light photoreceptor PHYTOCHROME B (PHYB) in the regulation of cellulose synthesis in the growing Arabidopsis hypocotyl...
  52. pmc Structure-guided engineering of plant phytochrome B with altered photochemistry and light signaling
    Junrui Zhang
    Department of Genetics, University of Wisconsin, Madison, WI 53706, USA
    Plant Physiol 161:1445-57. 2013
    ..initial attempt to apply structure-guided mutagenesis to phy engineering using Arabidopsis (Arabidopsis thaliana) phyB, the dominant isoform in light-grown plants, as the example...
  53. doi Phototropin 1 and cryptochrome action in response to green light in combination with other wavelengths
    Yihai Wang
    Horticultural Sciences Department, University of Florida, 1301 Fifield Hall, PO Box 110690, Gainesville, FL 32611, USA
    Planta 237:225-37. 2013
    ..The GL opposition of RL responses persists in phyA, phyB, cry1cry2 and phot2 mutants...
  54. pmc Phytochrome B inhibits binding of phytochrome-interacting factors to their target promoters
    Eunae Park
    Department of Biological Sciences, KAIST, Daejeon 305 701, Korea
    Plant J 72:537-46. 2012
    ..Here, we use chromatin immunoprecipitation to show that phyB inhibits the regulatory activity of PIF1 and PIF3 by releasing them from their DNA targets...
  55. pmc Intramolecular uncoupling of chromophore photoconversion from structural signaling determinants drive mutant phytochrome B photoreceptor to far-red light perception
    Stefan Kircher
    Institute of Biology II Faculty of Biology, University of Freiburg, Germany
    Plant Signal Behav 7:904-6. 2012
    ..Arabidopsis phyB together with phyC, D and E belongs to the relatively stable sensor class in comparison to the light labile phyA...
  56. pmc Deletion of the RS domain of RRC1 impairs phytochrome B signaling in Arabidopsis
    Hiromasa Shikata
    Kyushu University, Fukuoka, Japan
    Plant Signal Behav 7:933-6. 2012
    b>Phytochrome B (phyB), a major photoreceptor in plants, interacts with transcription factors to regulate gene expression and induce various light responses...
  57. doi Phytochrome B increases drought tolerance by enhancing ABA sensitivity in Arabidopsis thaliana
    Carina Verónica González
    IBAM Instituto de Biología Agrícola de Mendoza, CONICET Universidad Nacional de Cuyo, Facultad de Ciencias Agrarias, Alte Brown 500 5505, Chacras de Coria, Lujan de Cuyo, Mendoza, Argentina
    Plant Cell Environ 35:1958-68. 2012
    b>Phytochrome B (phyB) can adjust morphological and physiological responses according to changes in the red:far-red (R:FR) ratio...
  58. doi A non-covalently attached chromophore can mediate phytochrome B signaling in Arabidopsis
    Yoshito Oka
    RIKEN Plant Science Center, Yokohama, 230 0045 Japan
    Plant Cell Physiol 52:2088-102. 2011
    b>Phytochrome B (phyB) is the major informational photoreceptor in light-grown plants. The phyB polypeptide is folded into two domains, the N-terminal domain and the C-terminal domain...
  59. doi The RS domain of Arabidopsis splicing factor RRC1 is required for phytochrome B signal transduction
    Hiromasa Shikata
    Faculty of Agriculture, Kyushu University, Fukuoka 812 8581, Japan
    Plant J 70:727-38. 2012
    ..In seedling de-etiolation, phytochrome B (phyB), which is the most important member of the phytochrome family, interacts with transcription factors to ..
  60. pmc Cryptochrome 1 and phytochrome B control shade-avoidance responses in Arabidopsis via partially independent hormonal cascades
    Mercedes M Keller
    IFEVA, Consejo Nacional de Investigaciones Cientificas y Tecnicas, and Universidad de Buenos Aires, Avenida San Martin 4453, Buenos Aires, Argentina
    Plant J 67:195-207. 2011
    ..In Arabidopsis, this response (shade avoidance syndrome, SAS) is controlled by phytochromes (particularly phyB), and is dependent on the TAA1 pathway of auxin biosynthesis...
  61. doi Dimerization and blue light regulation of PIF1 interacting bHLH proteins in Arabidopsis
    Qingyun Bu
    Biological Laboratories, Section of Molecular Cell and Developmental Biology, The Institute for Cellular and Molecular Biology, The University of Texas at Austin, 205 W 24th St, Austin, TX 78712, USA
    Plant Mol Biol 77:501-11. 2011
    ..A PIF3 mutant defective in interaction with both phyA and phyB displayed reduced degradation under blue light, suggesting that phy-interaction was necessary for the blue light-..
  62. pmc Phytochromes inhibit hypocotyl negative gravitropism by regulating the development of endodermal amyloplasts through phytochrome-interacting factors
    Keunhwa Kim
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305 701, Korea
    Proc Natl Acad Sci U S A 108:1729-34. 2011
    ..Although the functions of phytochromes in gravitropism and chloroplast development are normally considered distinct, our results indicate that these two functions are closely related...
  63. pmc Integration of Phot1, Phot2, and PhyB signalling in light-induced chloroplast movements
    Darron R Luesse
    Department of Biological Sciences, Science Laboratory Building 3326, Southern Illinois University, Edwardsville, IL 62026, USA
    J Exp Bot 61:4387-97. 2010
    ..Mutations in phytochrome B (phyB) caused an enhanced avoidance response at intermediate and high light intensities...
  64. ncbi PKS1, a substrate phosphorylated by phytochrome that modulates light signaling in Arabidopsis
    C Fankhauser
    Plant Biology Laboratory, Howard Hughes Medical Institute, Salk Institute, La Jolla, CA 92037, USA
    Science 284:1539-41. 1999
    ..In vivo experiments suggest that PKS1 is phosphorylated in a phytochrome-dependent manner and negatively regulates phytochrome signaling. The data suggest that phytochromes signal by serine-threonine phosphorylation...
  65. ncbi The VLF loci, polymorphic between ecotypes Landsberg erecta and Columbia, dissect two branches of phytochrome A signal transduction that correspond to very-low-fluence and high-irradiance responses
    M J Yanovsky
    Departamento de Ecologia, Facultad de Agronomia, Universidad de Buenos Aires, Argentina
    Plant J 12:659-67. 1997
    ..dissected using phyA and phyB mutants of Arabidopsis thaliana (respectively lacking phytochrome A or phytochrome B) and a polymorphism between ecotypes Landsberg erecta and Columbia...
  66. ncbi NDPK2 as a signal transducer in the phytochrome-mediated light signaling
    Yu Shen
    Department of Chemistry, University of Nebraska, Lincoln, NE 68588 0304, USA
    J Biol Chem 280:5740-9. 2005
    ....
  67. ncbi Regulation of Arabidopsis SHY2/IAA3 protein turnover
    Qing Tian
    Department of Biology, University of North Carolina at Chapel Hill, CB 3280, Coker Hall, Chapel Hill, NC 27599 3280, USA
    Plant J 36:643-51. 2003
    ..assays, SHY2/IAA3 protein interacted with TIR1, the F-box component of SCFTIR1 and with the photoreceptor phytochrome B. Auxin stimulated SHY2/IAA3 interaction with TIR1, whereas the shy2-2 gain-of-function mutation decreased this ..
  68. ncbi A new type of mutation in phytochrome A causes enhanced light sensitivity and alters the degradation and subcellular partitioning of the photoreceptor
    Monika Dieterle
    Institut für Biologie 2 Botanik, Universitat Freiburg, Schanzlestrasse 1, 79104 Freiburg, Germany
    Plant J 41:146-61. 2005
    ..In contrast, the mutation stabilizes nuclear speckles (NUS) that appear late under continuous far-red light, whereas the formation of early, transiently appearing NUS remained more or less unaltered...
  69. ncbi Phytochrome-specific type 5 phosphatase controls light signal flux by enhancing phytochrome stability and affinity for a signal transducer
    Jong Sang Ryu
    Division of Molecular and Life Sciences and Systems Bio Dynamics Research Center, Pohang University of Science and Technology, Hyoja Dong, Pohang, Kyungbuk, 790 784, Republic of Korea
    Cell 120:395-406. 2005
    ....
  70. ncbi Analysis of the function of the photoreceptors phytochrome B and phytochrome D in Nicotiana plumbaginifolia and Arabidopsis thaliana
    Aurora Piñas Fernández
    Albert Ludwigs Universitat Freiburg, Institut für Biologie II Botanik, Schanzlestrasse 1, 79104 Freiburg, Germany
    Plant Cell Physiol 46:790-6. 2005
    ..The expression of 35S:NtPHYB:GFP and 35S:AtPHYB:GFP complemented the tobacco hgl2 and Arabidopsis phyB-9 mutations, whereas the 35S:AtPHYD:GFP only rescued the hgl2 mutant...
  71. pmc Forward genetic analysis of the circadian clock separates the multiple functions of ZEITLUPE
    Eva Kevei
    Institute of Plant Biology, Biological Research Centre of the Hungarian Academy of Sciences, Szeged
    Plant Physiol 140:933-45. 2006
    ..affect both circadian and developmental responses to red light, possibly through ZTL interaction with PHYTOCHROME B (PHYB). We conducted a large-scale genetic screen that identified additional clock-affecting loci...
  72. ncbi Regulation of hormone metabolism in Arabidopsis seeds: phytochrome regulation of abscisic acid metabolism and abscisic acid regulation of gibberellin metabolism
    Mitsunori Seo
    Growth Regulation Research Group, RIKEN Plant Science Center, Suehiro cho 1 7 22, Tsurumi, Yokohama, Kanagawa 230 0045, Japan
    Plant J 48:354-66. 2006
    ..with a far-red (FR) light pulse, and the reduction in ABA levels in response to R light was inhibited in a phytochrome B (PHYB)-deficient mutant...
  73. pmc Heterodimerization of type II phytochromes in Arabidopsis
    Robert A Sharrock
    Department of Plant Sciences and Plant Pathology, Montana State University, Bozeman, MT 59717, USA
    Proc Natl Acad Sci U S A 101:11500-5. 2004
    ..of these tagged proteins from seedling extracts coprecipitates additional type II phytochromes: six myc (myc6)-phyB coprecipitates phyC-phyE; and myc6-phyD coprecipitates phyB and phyE...
  74. ncbi Phytochrome coordinates Arabidopsis shoot and root development
    Frances J Salisbury
    Institute of Molecular Plant Sciences, Edinburgh University, Kings Buildings, Mayfield Road, Edinburgh, EH9 3JR, UK
    Plant J 50:429-38. 2007
    ..This new link between phytochrome and auxin may go some way to explain the extensive overlap in responses mediated by these two developmental regulators...
  75. ncbi Genetic linkages between circadian clock-associated components and phytochrome-dependent red light signal transduction in Arabidopsis thaliana
    Shogo Ito
    Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University, Chikusa ku, Nagoya, 464 8601 Japan
    Plant Cell Physiol 48:971-83. 2007
    ..these signaling pathways are coordinately integrated into the phytochrome-mediated red light signal transduction pathway, in which PIF3 (PHYTOCHROME-INTERACTING FACTOR 3) functions as a negative regulator immediately downstream of phyB.
  76. ncbi Phytochromes play a role in phototropism and gravitropism in Arabidopsis roots
    Melanie J Correll
    Department of Botany, Miami University, Oxford, OH 45056, USA
    Adv Space Res 31:2203-10. 2003
    ..Phytochrome A (phyA) and phyB mediate the positive red-light-based photoresponse in roots since single mutants (and the double phyAB mutant) were ..
  77. ncbi Characterization of the APRR9 pseudo-response regulator belonging to the APRR1/TOC1 quintet in Arabidopsis thaliana
    Shogo Ito
    Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University, Chikusa ku, Nagoya, 464 8601 Japan
    Plant Cell Physiol 44:1237-45. 2003
    ..These results are discussed within the context of a current consistent model of the Arabidopsis circadian oscillator...
  78. ncbi HYPERSENSITIVE TO RED AND BLUE 1 and its C-terminal regulatory function control FLOWERING LOCUS T expression
    Xiaojun Kang
    Department of Plant Biology, University of Minnesota, St Paul, MN 55108, USA
    Plant J 52:937-48. 2007
    ..In contrast, hrb1/phyB-9 showed a flowering phenotype and an FT expression pattern similar to phyB-9 over both long days and short days, ..
  79. pmc Distinct light and clock modulation of cytosolic free Ca2+ oscillations and rhythmic CHLOROPHYLL A/B BINDING PROTEIN2 promoter activity in Arabidopsis
    Xiaodong Xu
    Department of Biological Sciences, Vanderbilt University, Nashville, Tenessee 37235, USA
    Plant Cell 19:3474-90. 2007
    ..Both red and blue light regulate circadian oscillations of [Ca(2+)](cyt). Red light signaling is mediated by PHYTOCHROME B (PHYB). Blue light signaling occurs through the redundant action of CRYPTOCHROME1 (CRY1) and CRY2...
  80. pmc Phytochrome regulation of branching in Arabidopsis
    Scott A Finlayson
    Department of Soil and Crop Sciences, Texas A and M University, College Station, Texas 77843, USA
    Plant Physiol 152:1914-27. 2010
    ..Here, we show that in Arabidopsis, the negative effects of the phytochrome B mutation and of low red light:far-red light ratio on branching were largely due to reduced bud outgrowth ..
  81. pmc The Arabidopsis SRR1 gene mediates phyB signaling and is required for normal circadian clock function
    Dorothee Staiger
    Institute for Plant Sciences, Swiss Federal Institute of Technology, ETH Center, Zurich, Switzerland
    Genes Dev 17:256-68. 2003
    ..We have identified SRR1 (sensitivity to red light reduced), a gene that plays an important role in phytochrome B (phyB)-mediated light signaling...
  82. doi PKS1 plays a role in red-light-based positive phototropism in roots
    Maria Lia Molas
    Department of Botany, Miami University, Oxford, OH 45056, USA
    Plant Cell Environ 31:842-9. 2008
    ..positive phototropism relative to red light (RL), and this response is mediated by phytochromes A and B (phyA and phyB). Upon light stimulation, phyA and phyB interact with the phytochrome kinase substrate (PKS1) in the cytoplasm...
  83. ncbi Light signalling mediated by phytochrome plays an important role in cold-induced gene expression through the C-repeat/dehydration responsive element (C/DRE) in Arabidopsis thaliana
    Hyoun Joung Kim
    Kumho Life and Environmental Science Laboratory, Puk Gu, Gwang Ju, Korea
    Plant J 29:693-704. 2002
    ..Furthermore, GUS expression analysis in phyA or phyB or phyAphyB mutant backgrounds showed that phytochrome B is a primary photoreceptor responsible for the activation of cold-stress signalling in response to light...
  84. doi A novel protein phosphatase indirectly regulates phytochrome-interacting factor 3 via phytochrome
    Bong Kwan Phee
    Graduate School of Biotechnology and Plant Metabolism Research Center, Kyung Hee University, Yongin, Korea, 446 701
    Biochem J 415:247-55. 2008
    ..PAPP2C (phytochrome-associated protein phosphatase type 2C), interacts in the nucleus with phyA (phytochrome A) and phyB, both in vitro and in vivo...
  85. pmc ELF3 encodes a circadian clock-regulated nuclear protein that functions in an Arabidopsis PHYB signal transduction pathway
    X L Liu
    Institute of Molecular Biology, University of Oregon, Eugene, Oregon 97403, USA
    Plant Cell 13:1293-304. 2001
    ..Loss-of-function mutations in the Arabidopsis EARLY FLOWERING 3 (ELF3) and PHYTOCHROME B (PHYB) genes cause early flowering and influence the activity of circadian clock-regulated processes...
  86. pmc Obligate heterodimerization of Arabidopsis phytochromes C and E and interaction with the PIF3 basic helix-loop-helix transcription factor
    Ted Clack
    Department of Plant Sciences and Plant Pathology, Montana State University, Bozeman, Montana 59717, USA
    Plant Cell 21:786-99. 2009
    ..Arabidopsis thaliana genome encodes five phytochrome apoproteins: type I phyA mediates responses to FR, and type II phyB-phyE mediate shade avoidance and classical R/FR-reversible responses...
  87. doi The Dof protein DAG1 mediates PIL5 activity on seed germination by negatively regulating GA biosynthetic gene AtGA3ox1
    Stefano Gabriele
    Istituto Pasteur Fondazione Cenci Bolognetti, Dipartimento di Genetica e Biologia Molecolare, Universita La Sapienza, Piazzale Aldo Moro 5, 00185 Rome, Italy
    Plant J 61:312-23. 2010
    ..transcription factor DOF AFFECTING GERMINATION 1 (DAG1) renders seed germination more sensitive to both phytochrome B (phyB) and gibberellins (GA)...
  88. pmc Phytochrome B binds with greater apparent affinity than phytochrome A to the basic helix-loop-helix factor PIF3 in a reaction requiring the PAS domain of PIF3
    Y Zhu
    Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA
    Proc Natl Acad Sci U S A 97:13419-24. 2000
    ..Evidence for a relatively direct pathway has been provided by the binding of one member of the family, phyB, to a promoter-element-bound, basic helix-loop-helix protein, PIF3, specifically upon light-induced conversion of ..
  89. pmc The out of phase 1 mutant defines a role for PHYB in circadian phase control in Arabidopsis
    Patrice A Salome
    Department of Biological Sciences, 6044 Gilman Laboratories, Dartmouth College, Hanover, New Hampshire 03755 3576, USA
    Plant Physiol 129:1674-85. 2002
    ..Here, we characterize one mutant, out of phase 1 (oop1), with the circadian phenotype of altered phase...
  90. doi Phytochrome-regulated PIL1 derepression is developmentally modulated
    Yong Sic Hwang
    Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA
    Plant Cell Physiol 49:501-11. 2008
    ..Analysis of phy-null mutants indicates that multiple phytochromes, including phyA and phyB, impose this repression...
  91. ncbi An Arabidopsis circadian clock component interacts with both CRY1 and phyB
    J A Jarillo
    Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6018, USA
    Nature 410:487-90. 2001
    ..Both yeast two-hybrid and in vitro binding studies show that there is a physical interaction between ADO1 and the photoreceptors CRY1 and phyB. We propose that ADO1 is an important component of the Arabidopsis circadian system.
  92. ncbi Identification of phytochrome-interacting protein candidates in Arabidopsis thaliana by co-immunoprecipitation coupled with MALDI-TOF MS
    Bong Kwan Phee
    Graduate School of Biotechnology and Plant Metabolism Research Center, Kyung Hee University, Suwon, Korea
    Proteomics 6:3671-80. 2006
    ..these candidates were predicted to be putative phytochrome A-interacting proteins and the remaining ones to be phytochrome B-interacting proteins...
  93. ncbi The GRAS protein SCL13 is a positive regulator of phytochrome-dependent red light signaling, but can also modulate phytochrome A responses
    Patricia Torres-Galea
    Department für Biologie I Bereich Botanik, Ludwig Maximilians University, Menzinger Str 67, 80638, Munich, Germany
    Mol Genet Genomics 276:13-30. 2006
    ..Scarecrow-like (SCL)13, which serves as a positive regulator of continuous red light signals downstream of phytochrome B (phyB)...
  94. pmc Cryptochromes are required for phytochrome signaling to the circadian clock but not for rhythmicity
    P F Devlin
    Department of Cell Biology, Scripps Research Institute, La Jolla, California 92037, USA
    Plant Cell 12:2499-2510. 2000
    ..We demonstrate that the phytochromes phyA, phyB, phyD, and phyE act as photoreceptors in red light input to the clock and that phyA and the cryptochromes cry1 and ..