UVH6

Summary

Gene Symbol: UVH6
Description: RAD3-like DNA-binding helicase protein
Alias: ARABIDOPSIS THALIANA XERODERMA PIGMENTOSUM GROUP D, ATXPD, ULTRAVIOLET HYPERSENSITIVE 6
Species: thale cress

Top Publications

  1. pmc Evidence that heat and ultraviolet radiation activate a common stress-response program in plants that is altered in the uvh6 mutant of Arabidopsis thaliana
    M E Jenkins
    Department of Molecular and Cellular Biology, University of Arizona, Tucson 85721, USA
    Plant Physiol 115:1351-8. 1997
  2. pmc Arabidopsis UVH6, a homolog of human XPD and yeast RAD3 DNA repair genes, functions in DNA repair and is essential for plant growth
    Zongrang Liu
    Departments of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona 85721, USA
    Plant Physiol 132:1405-14. 2003
  3. pmc Heat stress phenotypes of Arabidopsis mutants implicate multiple signaling pathways in the acquisition of thermotolerance
    Jane Larkindale
    Department of Biochemistry and Molecular Biophysics, University of Arizona, Tucson, Arizona 85721, USA
    Plant Physiol 138:882-97. 2005
  4. doi Interactions between Arabidopsis DNA repair genes UVH6, DDB1A, and DDB2 during abiotic stress tolerance and floral development
    Valentina Ly
    Department of Biological Sciences, University of Manitoba, Winnipeg, MB, Canada
    Plant Sci 213:88-97. 2013
  5. doi Genome stability in the uvh6 mutant of Arabidopsis thaliana
    Andriy Bilichak
    Department of Biological Sciences, University of Lethbridge, University Drive 4401, Lethbridge, AB, T1K 3M4, Canada
    Plant Cell Rep 33:979-91. 2014
  6. pmc Genetic interactions between Arabidopsis DET1 and UVH6 during development and abiotic stress response
    Esther Kim
    Department of Biological Sciences, University of Manitoba, Winnipeg, MB, Canada
    G3 (Bethesda) 2:913-20. 2012
  7. ncbi Arabidopsis homologue of human transcription factor IIH/nucleotide excision repair factor p44 can function in transcription and DNA repair and interacts with AtXPD
    Edward J Vonarx
    School of Life and Environmental Sciences, Deakin University, Geelong, Victoria 3217, Australia
    Plant J 46:512-21. 2006

Scientific Experts

  • Andriy Bilichak
  • Valentina Ly
  • Esther Kim
  • Avril Hatherell
  • Dana F Schroeder
  • Edward J Vonarx
  • Jane Larkindale
  • Elizabeth Vierling
  • Jennifer D Hall
  • Zongrang Liu
  • Ainsley Chan
  • Mark F Belmonte
  • Megan J Osmond
  • Emma K Tabone
  • Bernard A Kunz
  • Heather J Anderson
  • Marc R Knight
  • M E Jenkins
  • Mindy Escobar
  • Suk Whan Hong
  • David W Mount
  • David L Mitchell
  • T C Suzuki
  • D W Mount

Detail Information

Publications7

  1. pmc Evidence that heat and ultraviolet radiation activate a common stress-response program in plants that is altered in the uvh6 mutant of Arabidopsis thaliana
    M E Jenkins
    Department of Molecular and Cellular Biology, University of Arizona, Tucson 85721, USA
    Plant Physiol 115:1351-8. 1997
    The uvh6 mutant of Arabidopsis was previously isolated in a screen for increased sensitivity to ultraviolet (UV) radiation. uvh6 mutant plants were killed by incubation at 37 degrees C for 4 d, a treatment not lethal to wild-type plants...
  2. pmc Arabidopsis UVH6, a homolog of human XPD and yeast RAD3 DNA repair genes, functions in DNA repair and is essential for plant growth
    Zongrang Liu
    Departments of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona 85721, USA
    Plant Physiol 132:1405-14. 2003
    ..We have mapped the uvh6-1 locus to chromosome I and have identified a candidate gene, AtXPD, within the corresponding region...
  3. pmc Heat stress phenotypes of Arabidopsis mutants implicate multiple signaling pathways in the acquisition of thermotolerance
    Jane Larkindale
    Department of Biochemistry and Molecular Biophysics, University of Arizona, Tucson, Arizona 85721, USA
    Plant Physiol 138:882-97. 2005
    ..g. fatty acid desaturase mutants, uvh6)...
  4. doi Interactions between Arabidopsis DNA repair genes UVH6, DDB1A, and DDB2 during abiotic stress tolerance and floral development
    Valentina Ly
    Department of Biological Sciences, University of Manitoba, Winnipeg, MB, Canada
    Plant Sci 213:88-97. 2013
    ..Damaged DNA binding protein 1A (DDB1A), DDB2, and UV hypersensitive 6 (UVH6)/XPD are all involved in the repair of UV-damaged DNA - DDB1A and DDB2 in the initial damage recognition stage, ..
  5. doi Genome stability in the uvh6 mutant of Arabidopsis thaliana
    Andriy Bilichak
    Department of Biological Sciences, University of Lethbridge, University Drive 4401, Lethbridge, AB, T1K 3M4, Canada
    Plant Cell Rep 33:979-91. 2014
    Plant XPD homolog UVH6 is the protein involved in the repair of strand breaks, and the excision repair and uvh6 mutant is not impaired in transgenerational increase in HRF...
  6. pmc Genetic interactions between Arabidopsis DET1 and UVH6 during development and abiotic stress response
    Esther Kim
    Department of Biological Sciences, University of Manitoba, Winnipeg, MB, Canada
    G3 (Bethesda) 2:913-20. 2012
    ..UV-HYPERSENSITIVE 6 (UVH6) mutants are UV and heat sensitive, as well as dwarf and pale, like det1...
  7. ncbi Arabidopsis homologue of human transcription factor IIH/nucleotide excision repair factor p44 can function in transcription and DNA repair and interacts with AtXPD
    Edward J Vonarx
    School of Life and Environmental Sciences, Deakin University, Geelong, Victoria 3217, Australia
    Plant J 46:512-21. 2006
    ..Here we address the capabilities of Arabidopsis thaliana AtGTF2H2 and AtXPD, homologues of the essential interacting human/yeast TFIIH components p44/Ssl1 and XPD/Rad3, respectively...