- IL-17 receptor adaptor protein Act1/CIKS plays an evolutionarily conserved role in antiviral signalingGrigory Ryzhakov
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Kennedy Institute of Rheumatology, University of Oxford, London W6 8LH, United Kingdom
J Immunol 189:4852-8. 2012..In this study, we show that the IL-17R adaptor protein Act1/CIKS is involved in this process...
- Evolution of vertebrate immunity: sequence and functional analysis of the SEFIR domain family member Act1Grigory Ryzhakov
Kennedy Institute of Rheumatology Division, Imperial College of Science, Technology and Medicine, Hammersmith, London, UK
J Mol Evol 72:521-30. 2011SEF/IL-17R/CIKS/ACT1 homology (SEFIR) domain containing proteins, which include the IL-17 receptors and an adaptor protein Act1, have essential roles in vertebrate immunity...