Candida rugosa

Summary

Alias: Candida rugasa

Top Publications

  1. pmc Structural classification by the Lipase Engineering Database: a case study of Candida antarctica lipase A
    Michael Widmann
    Institute of Technical Biochemistry, University of Stuttgart, Allmandring 31, 70569 Stuttgart, Germany
    BMC Genomics 11:123. 2010
  2. pmc Multidrug resistant yeasts in synanthropic wild birds
    Alexander Tiong Kah Lord
    The International Medical University, Kuala Lumpur, Malaysia
    Ann Clin Microbiol Antimicrob 9:11. 2010
  3. ncbi Lipase-catalysed hydrolysis of short-chain substrates in solution and in emulsion: a kinetic study
    L Nini
    Laboratory of Applied Biochemistry, Faculty of Sciences and Technology, , France
    Biochim Biophys Acta 1534:34-44. 2001
  4. ncbi In-vitro antifungal activity of liposomal nystatin in comparison with nystatin, amphotericin B cholesteryl sulphate, liposomal amphotericin B, amphotericin B lipid complex, amphotericin B desoxycholate, fluconazole and itraconazole
    A J Carrillo-Munoz
    Department of Microbiology, Asesoría Científica y de Investigación Aplicada, Barcelona, Spain
    J Antimicrob Chemother 44:397-401. 1999
  5. ncbi Pancreatic carboxylester lipase from Atlantic salmon (Salmo salar). cDNA sequence and computer-assisted modelling of tertiary structure
    D R Gjellesvik
    Laboratory for Marine Molecular Biology, University of Bergen, Norway
    Eur J Biochem 226:603-12. 1994
  6. ncbi Recovery of sterols as fatty acid steryl esters from waste material after purification of tocopherols
    Toshihiro Nagao
    Osaka Municipal Technical Research Institute, Osaka 536 8553, Japan
    Lipids 39:789-94. 2004
  7. pmc Cloning of the Zygosaccharomyces bailii GAS1 homologue and effect of cell wall engineering on protein secretory phenotype
    Simone Passolunghi
    Department of Biotechnology and Bioscience, University of Milano Bicocca, Milan, Italy
    Microb Cell Fact 9:7. 2010
  8. doi Esterification and hydrolytic activities of Candida rugosa lipase isoform 1 (LIP1) immobilized on celite 545, duolite A7, and sephadex G-25
    Stephen E Lumor
    Department of Food Science and Technology, Food Science Building, The University of Georgia, Athens, Georgia 30602 7610, USA
    J Agric Food Chem 56:10396-8. 2008
  9. doi Monoglycerides and diglycerides synthesis in a solvent-free system by lipase-catalyzed glycerolysis
    Patricia Bogalhos Lucente Fregolente
    Separation Process Development Laboratory, Chemical Engineering School, State University of Campinas, Campinas, Sao Paolo, Brazil
    Appl Biochem Biotechnol 146:165-72. 2008
  10. ncbi Reusability of surfactant-coated Candida rugosa lipase immobilized in gelatin microemulsion-based organogels for ethyl isovalerate synthesis
    Vrushali Dandavate
    BRD School of Biosciences, Sardar Patel Maidan, Vadtal Road P O Box 39, Satellite Campus, Sardar Patel University, Vallabh Vidyanagar 388120 Gujarat, India
    J Microbiol Biotechnol 18:735-41. 2008

Research Grants

Patents

  1. BIOLOGICAL METHODS FOR PREPARING A FATTY DICARBOXYLIC ACID
  2. A method for producing an L-amino acid
  3. Recombinant candida rugosa lipases
  4. Highly conserved genes and their use to generate probes and primers for detection of microorganisms
  5. Process for the production of a fine chemical
  6. A method for producing an L-amino acid
  7. A method for producing an L-amino acid
  8. Method of producing L-amino acid
  9. RECOMBINANT CANDIDA RUGOSA LIPASES
  10. RECOMBINANT CANDIDA RUGOSA LIPASES

Detail Information

Publications179 found, 100 shown here

  1. pmc Structural classification by the Lipase Engineering Database: a case study of Candida antarctica lipase A
    Michael Widmann
    Institute of Technical Biochemistry, University of Stuttgart, Allmandring 31, 70569 Stuttgart, Germany
    BMC Genomics 11:123. 2010
    ..This involved the comparison of CALA to similar structures as well as sequence-based comparisons against the content of the LED...
  2. pmc Multidrug resistant yeasts in synanthropic wild birds
    Alexander Tiong Kah Lord
    The International Medical University, Kuala Lumpur, Malaysia
    Ann Clin Microbiol Antimicrob 9:11. 2010
    ..The aim of this study was to investigate the presence of multidrug resistant yeasts in the faeces of synanthropic wild birds from the Bangsar suburb of Kuala Lumpur...
  3. ncbi Lipase-catalysed hydrolysis of short-chain substrates in solution and in emulsion: a kinetic study
    L Nini
    Laboratory of Applied Biochemistry, Faculty of Sciences and Technology, , France
    Biochim Biophys Acta 1534:34-44. 2001
    ..hydrolysis of short-chain substrates by microbial triacylglycerol lipases from Rhizopus oryzae, Mucor miehei, Candida rugosa, Candida antarctica A and by (phospho)lipase from guinea-pig pancreas show that these lipolytic enzymes follow ..
  4. ncbi In-vitro antifungal activity of liposomal nystatin in comparison with nystatin, amphotericin B cholesteryl sulphate, liposomal amphotericin B, amphotericin B lipid complex, amphotericin B desoxycholate, fluconazole and itraconazole
    A J Carrillo-Munoz
    Department of Microbiology, Asesoría Científica y de Investigación Aplicada, Barcelona, Spain
    J Antimicrob Chemother 44:397-401. 1999
    ..krusei, Candida guilliermondii, Candida tropicalis, Candida kefyr, Candida viswanathii, Candida famata, Candida rugosa, Rhodotorula rubra, Trichosporon spp., Cryptococcus laurentii and Cryptococcus neoformans...
  5. ncbi Pancreatic carboxylester lipase from Atlantic salmon (Salmo salar). cDNA sequence and computer-assisted modelling of tertiary structure
    D R Gjellesvik
    Laboratory for Marine Molecular Biology, University of Bergen, Norway
    Eur J Biochem 226:603-12. 1994
    ..The carboxylester lipase structural homolog to the 'flap' of the lipases from Geotrichum candidum and Candida rugosa contains a carboxylester-lipase-conserved deletion that renders this region unable to cover the active site...
  6. ncbi Recovery of sterols as fatty acid steryl esters from waste material after purification of tocopherols
    Toshihiro Nagao
    Osaka Municipal Technical Research Institute, Osaka 536 8553, Japan
    Lipids 39:789-94. 2004
    ..We thus attempted to purify sterols by a process including a lipase-catalyzed reaction. Candida rugosa lipase efficiently esterified sterols in TC waste with oleic acid (OA)...
  7. pmc Cloning of the Zygosaccharomyces bailii GAS1 homologue and effect of cell wall engineering on protein secretory phenotype
    Simone Passolunghi
    Department of Biotechnology and Bioscience, University of Milano Bicocca, Milan, Italy
    Microb Cell Fact 9:7. 2010
    ..The aim of this study was the cloning and deletion of the GAS1 homologue of Z. bailii and the evaluation of its deletion on recombinant protein secretion...
  8. doi Esterification and hydrolytic activities of Candida rugosa lipase isoform 1 (LIP1) immobilized on celite 545, duolite A7, and sephadex G-25
    Stephen E Lumor
    Department of Food Science and Technology, Food Science Building, The University of Georgia, Athens, Georgia 30602 7610, USA
    J Agric Food Chem 56:10396-8. 2008
    The esterification and hydrolytic activities of free and immobilized Candida rugosa lipase isoform 1 (LIP1) were investigated...
  9. doi Monoglycerides and diglycerides synthesis in a solvent-free system by lipase-catalyzed glycerolysis
    Patricia Bogalhos Lucente Fregolente
    Separation Process Development Laboratory, Chemical Engineering School, State University of Campinas, Campinas, Sao Paolo, Brazil
    Appl Biochem Biotechnol 146:165-72. 2008
    Five lipases were screened (Thermomyces lanuginosus free and immobilized forms, Candida antarctica B, Candida rugosa, Aspergillus niger, and Rhizomucor miehei) to study their ability to produce monoglycerides (MG) and diglycerides (DG) ..
  10. ncbi Reusability of surfactant-coated Candida rugosa lipase immobilized in gelatin microemulsion-based organogels for ethyl isovalerate synthesis
    Vrushali Dandavate
    BRD School of Biosciences, Sardar Patel Maidan, Vadtal Road P O Box 39, Satellite Campus, Sardar Patel University, Vallabh Vidyanagar 388120 Gujarat, India
    J Microbiol Biotechnol 18:735-41. 2008
    In our previous study, a surfactant-coated Candida rugosa lipase immobilized in microemulsion-based organogels was exploited for the synthesis of ethyl isovalerate...
  11. ncbi Enzymatic resolution to (-)-ormeloxifene intermediates from their racemates using immobilized Candida rugosa lipase
    S V Lehmann
    Analytical Development, Pharmaceuticals Development, Novo Nordisk A S, Novo Nordisk Park, Måløv, Denmark
    Chirality 12:568-73. 2000
    ..Five commercially available lipases, Candida rugosa lipase, Candida antarctica lipase B, Mucor miehei lipase, Pseudomonas cepacia lipase, and Humicola lanuginosa ..
  12. doi Recombinant Candida rugosa lipase 2 from Pichia pastoris: immobilization and use as biocatalyst in a stereoselective reaction
    M Dolors Benaiges
    Departament d Enginyeria Química ETSE Universitat Autònoma de Barcelona, Barcelona, Spain
    Biotechnol Prog 26:1252-8. 2010
    The characterization of the recombinant Candida rugosa Lip2 (r-Lip2) isoenzyme obtained from fed-batch cultures of Pichia pastoris under PAOX promoter was carried out, determining the optimal pH and temperature as well as their catalytic ..
  13. ncbi Immobilization of Candida rugosa lipase on magnetized Dacron: kinetic study
    M C B Pimentel
    Dept Bioquímica UFPE, Lab Immunopatologia Keizo Asami, Federal University of Pernambuco, Recife, Brazil
    Artif Cells Blood Substit Immobil Biotechnol 35:221-35. 2007
    b>Candida rugosa lipase has been covalently immobilized on ferromagnetic azide polyethyleneterepthalate (Dacron) with specific activity retention of 16% for 4-nitrophenyl palmitate and 24% for hydrolysis of triolein in hexane...
  14. ncbi Covalent attachment of Candida rugosa lipase on chemically modified hybrid matrix of polysiloxane-polyvinyl alcohol with different activating compounds
    Julio C Santos
    Engineering School of Lorena University of São Paulo, PO Box 116, Lorena 12 602 810, SP, Brazil
    Colloids Surf B Biointerfaces 61:229-36. 2008
    b>Candida rugosa lipase was immobilized by covalent binding on hybrid matrix of polysiloxane-polyvinyl alcohol chemically modified with different activating agents as glutaraldehyde, sodium metaperiodate and carbonyldiimidazole...
  15. doi Antimicrobial effects of Turkish propolis, pollen, and laurel on spoilage and pathogenic food-related microorganisms
    Osman Erkmen
    Department of Food Engineering, Faculty of Engineering, University of Gaziantep, Gaziantep, Turkey
    J Med Food 11:587-92. 2008
    ..enterocolitica, Enterococcus faecalis, and Listeria monocytogenes), yeasts (Saccharomyces cerevisiae and Candida rugosa), and molds (Aspergillus niger and Rhizopus oryzae)...
  16. ncbi In vitro activity of fluconazole and voriconazole against clinical isolates of Candida spp. by E-test method
    P Madhavan
    Department of Medical Microbiology and Parasitology, Faculty of Medicine and Health Sciences, University Putra Malaysia, Serdang, Selangor, Malaysia
    Trop Biomed 27:200-7. 2010
    ..These comprised Candida tropicalis, Candida albicans, Candida krusei, Candida parapsilosis, Candida rugosa, Candida dubliniensis and Candida glabrata...
  17. doi A chemoenzymatic approach to the synthesis of enantiomerically pure (S)-3-hydroxy-gamma-butyrolactone
    Sang Hyun Lee
    LG Chem, Ltd Research Park, Corporate R and D 104 1, Moonji dong, Yusung Gu, Daejon, South Korea
    Appl Microbiol Biotechnol 79:355-62. 2008
    ..Lipase from Candida rugosa was found to be the most efficient enzyme for the hydrolysis of (S)-beta-benzoyloxy-gamma-butyrolactone...
  18. doi Covalent immobilization of lipase from Candida rugosa onto poly(acrylonitrile-co-2-hydroxyethyl methacrylate) electrospun fibrous membranes for potential bioreactor application
    Xiao Jun Huang
    Institute of Polymer Science, Key Laboratory of Macromolecular Synthesis and Functionalization Ministry of Education, Zhejiang University, Hangzhou 310027, PR China
    Bioresour Technol 99:5459-65. 2008
    ..Lipase from Candida rugosa was covalently immobilized on these fibrous membranes...
  19. doi Stabilization of Candida rugosa lipase during transacetylation with vinyl acetate
    Abir B Majumder
    Chemistry Department, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110 016, India
    Bioresour Technol 101:2877-9. 2010
    An optimally prepared Candida rugosa lipase aggregate cross-linked with bovine serum albumin, was found to overcome acetaldehyde deactivation during transacetylation of a series of benzyl alcohols with vinyl acetate...
  20. ncbi Synthesis and characterization of canola oil-stearic acid-based trans-free structured lipids for possible margarine application
    Stephen E Lumor
    Department of Food Science and Technology, University of Georgia, Athens 30602, USA
    J Agric Food Chem 55:10692-702. 2007
    ..Response surface methodology was used to study the effects of lipozyme RM IM from Rhizomucor miehei and Candida rugosa lipase isoform 1 (LIP1) and two acyl donors, stearic acid and ethyl stearate, on the incorporation...
  21. doi Screening of food grade lipases to be used in esterification and interesterification reactions of industrial interest
    Ariela Veloso de Paula
    Engineering School of Lorena, University of Sao Paulo, P O Box 116, Lorena, 12602 810 São Paulo, Brazil
    Appl Biochem Biotechnol 160:1146-56. 2010
    ..The highest esterification activity (240.63 microM/g min) was achieved by Candida rugosa lipase, while the highest interesterification yield (31%, in 72 h) was achieved by lipase from Rhizopus oryzae,..
  22. ncbi Microbial spoilage of date rutab collected from the markets of Al-Hofuf city in the Kingdom of Saudi Arabia
    Siddig Hussein Hamad
    Department of Food Science and Nutrition, College of Agricultural and Food Sciences, King Faisal University, P O Box 420, Al Hofuf 31982, Kingdom of Saudi Arabia
    J Food Prot 71:1406-11. 2008
    ..Lactobacillus salivarius, Zygosaccharomyces mellis or Zygosaccharomyces rouxii, Candida sphaerica, Candida rugosa, Candida colliculosa, Candida pelliculosa, Candida famata, Pichia anomala, Aspergillus niger, and Penicillium ..
  23. ncbi Alternatives to amphotericin B for Candida rugosa infection
    Steve Hernandez
    Department of Medicine, Division of Infectious Diseases, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
    J Antimicrob Chemother 54:477-80. 2004
    Amphotericin B failure is frequently seen in patients with candidaemia caused by Candida rugosa. We evaluated amphotericin B, fluconazole, posaconazole and voriconazole as alternative treatments against infection in mice with two isolates ..
  24. ncbi Hydrolysis of steryl esters by a lipase (Lip 3) from Candida rugosa
    M Tenkanen
    VTT Biotechnology, Finland
    Appl Microbiol Biotechnol 60:120-7. 2002
    A well-known lipase, Lip 3 of Candida rugosa, was purified to homogeneity from a commercial lipase preparation, using hydrophobic interaction and anion exchange chromatography...
  25. ncbi Altering the substrate specificity of Candida rugosa LIP4 by engineering the substrate-binding sites
    Li Chiun Lee
    Institute of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan
    J Agric Food Chem 55:5103-8. 2007
    b>Candida rugosa (formerly Candida cylindracea) lipase (CRL) is an important industrial enzyme that is widely used in biotechnological applications such as the production of fatty acids and the synthesis of various esters...
  26. doi Production of n-3 polyunsaturated fatty acid concentrate from sardine oil by immobilized Candida rugosa lipase
    T Okada
    Oregon State University, Seafood Laboratory, 2001 Marine Drive, Rm 253, Astoria, OR 97103, USA
    J Food Sci 73:C146-50. 2008
    ..6% and 69.5% of total FFAs (after 1st and 2nd hydrolysis, respectively). This study shows that use of immobilized lipase systems for increasing n-3 PUFA concentration in sardine oil provides new processing opportunities for the industry...
  27. doi Commercially viable resolution of ibuprofen
    David Chávez-Flores
    Department of Chemistry, University of Texas at El Paso, 79968, USA
    Biotechnol J 4:1222-4. 2009
    ..b>Candida rugosa lipase was used to enantioselectively esterify racemic ibuprofen with decan-1-ol and butan-1-ol in cyclohexane ..
  28. ncbi Optimization of the process for biodiesel production using a mixture of immobilized Rhizopus oryzae and Candida rugosa lipases
    Jong Ho Lee
    Department of Chemical and Biological Engineering, Korea University, Seoul 136 701, Korea
    J Microbiol Biotechnol 18:1927-31. 2008
    ..enzymatic process for biodiesel production was optimized using a mixture of immobilized Rhizopus oryzae and Candida rugosa lipases...
  29. doi Study of a sterol esterase secreted by Ophiostoma piceae: sequence, model and biochemical properties
    Olga Calero-Rueda
    Centro de Investigaciones Biologicas, Consejo Superior de Investigaciones Cientificas, Ramiro de Maeztu 9, E 28040 Madrid, Spain
    Biochim Biophys Acta 1794:1099-106. 2009
    ..A search for proteins with related amino acid sequences revealed around 40% identity with lipases from Candida rugosa and Geotrichum candidum. Modelling the O. piceae enzyme, using the crystal structures of Lip1 and Lip3 from C...
  30. ncbi Adsorption and activity of lipase from Candida rugosa on the chitosan-modified poly(acrylonitrile-co-maleic acid) membrane surface
    Peng Ye
    Institute of Polymer Science, and Key Laboratory of Macromolecular Synthesis and Functionalization Ministry of Education, Zhejiang University, Hangzhou 310027, PR China
    Colloids Surf B Biointerfaces 60:62-7. 2007
    ..Lipase from Candida rugosa was immobilized on this dual-layer biomimetic support by adsorption...
  31. doi Impact of inoculation strategy on the progress of Candida rugosa cultivation
    Serpil Takac
    Ankara University Faculty of Engineering, Department of Chemical Engineering, Ankara, Turkey
    Artif Cells Blood Substit Immobil Biotechnol 37:130-7. 2009
    Batch cultivation of Candida rugosa for the production of lipase and esterase enzymes was carried out by employing two different inoculation strategies...
  32. ncbi The acetates of p-nitrophenyl alpha-L-arabinofuranoside--regioselective preparation by action of lipases
    Mária Mastihubová
    Institute of Chemistry, Slovak Academy of Sciences, SK 845 38 Bratislava, Slovakia
    Bioorg Med Chem 14:1805-10. 2006
    ..group of per-O-acetylated p-nitrophenyl alpha-L-arabinofuranoside by Candida cylindracea lipase (CCL) or Candida rugosa lipase (LAY)...
  33. doi Dual response surface-optimized synthesis of L-menthyl conjugated linoleate in solvent-free system by Candida rugosa lipase
    Zhen Li
    School of Biotechnology, Southern Medical University, Guangzhou, Guangdong Province 510515, PR China
    Bioresour Technol 101:1305-9. 2010
    ..1+/-0.8%) was obtained at 30 degrees C, Candida rugosa lipase of 33...
  34. ncbi [High expression of LIP1 in Pichia pastoris]
    Jin Long Bei
    The State Key Laboratory for Biological Control, Biopharmaceutical Center, Zhongshan University, Guangzhou 510275, China
    Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 35:366-70. 2003
    The gene of LIP1, the most important isoenzyme of Candida rugosa lipase (CRL), was artificially synthesized according to its mature peptide sequence. It consisted of 20 codons of preference in Pichia pastoris...
  35. ncbi Isolation and characterization of novel long-chain acyl-CoA thioesterase/carboxylesterase isoenzymes from Candida rugosa
    M A Diczfalusy
    Department of Medical Laboratory Sciences and Technology, Karolinska Institutet, Huddinge University Hospital, Sweden
    Arch Biochem Biophys 334:104-12. 1996
    ..Therefore a commercial lipase preparation from the yeast Candida rugosa was investigated and found to contain high myristoyl-CoA thioesterase activity...
  36. ncbi [Yeasts in domestic animals: species identification and susceptibility to antifungals]
    Petr Hamal
    Department of Microbiology, Faculty of Medicine and Dentistry, Palacky University in Olomouc, Olomouc, Czech Republic
    Klin Mikrobiol Infekc Lek 16:4-9. 2010
    ..On the other hand, cow and pig were clearly dominated by Candida krusei (from 7 species) and Candida rugosa (from 5 species), respectively...
  37. doi Production of ricinoleic acid from castor oil by immobilised lipases
    Hakki Mevlut Ozcan
    Faculty of Science and Letters, Department of Chemistry, Trakya University, Edirne, Turkey
    Prep Biochem Biotechnol 39:170-82. 2009
    Porcine pancreatic lipase (PPL), Candida rugosa lipase (CRL), and Castor bean lipase (CBL) were immobilized on celite by deposition from aqueous solution by the addition of hexane...
  38. ncbi Lipase specificity toward some acetylenic and olefinic alcohols in the esterification of pentanoic and stearic acids
    M S Lie Ken Jie
    Department of Chemistry, The University of Hong Kong, Hong Kong
    Lipids 33:861-7. 1998
    ..With the exception of 2-nonyn-1-ol, where Lipase AY-30 (Candida rugosa) was used as the biocatalyst, the esterification of C11, C18, and C22 acetylenic alcohols with pentanoic acid ..
  39. ncbi A water activity control system for enzymatic reactions in organic media
    Anna E V Petersson
    Department of Biotechnology, Center for Chemistry and Chemical Engineering, Lund University, P O Box 124, SE 22100 Lund, Sweden
    Biotechnol Bioeng 97:235-41. 2007
    ..different lipase preparations, namely, Novozym 435 (immobilised Candida antarctica lipase B) and immobilised Candida rugosa lipase, were also performed. Novozym 435 catalyses reactions very well at extremely low water activity while C...
  40. doi A convenient test for lipase activity in aqueous-based solutions
    Jin Guo
    Key Laboratory of Eco Textile Jiangnan University, Ministry of Education, Wuxi, Jiangsu 214122, China
    Enzyme Microb Technol 71:8-12. 2015
    ..In this work, lipase from Candida rugosa was used as the model lipase to test its catalytic ability toward p-nitrophenyl palmitate (p-NPP), which was ..
  41. ncbi Nanofibrous poly(acrylonitrile-co-maleic acid) membranes functionalized with gelatin and chitosan for lipase immobilization
    Peng Ye
    Institute of Polymer Science, Zhejiang University, Hangzhou 310027, PR China
    Biomaterials 27:4169-76. 2006
    ..Lipase from Candida rugosa was then immobilized on these dual-layer biomimetic supports using glutaraldehyde (GA), and on the nascent ..
  42. doi Epidemiology of candidaemia in critically ill trauma patients: experiences of a level I trauma centre in North India
    Rohit Inder Singh
    Department of Microbiology, All India Institute of Medical Sciences AIIMS, New Delhi 110029, India
    J Med Microbiol 60:342-8. 2011
    ..A total of 136 Candida isolates were obtained, with non-albicans Candida species accounting for over 80 %. Candida rugosa, a rarely isolated pathogen, accounted for 25 (18.4 %) of the isolates, and 5...
  43. ncbi Candida rugosa lipase-catalysed kinetic resolution of 2-substituted-aryloxyacetic esters with dimethylsulfoxide and isopropanol as additives
    Alessandra Ammazzalorso
    Department of Drug Sciences, University of Chieti G D Annunzio, Via dei Vestini, Chieti, Italy
    Chirality 20:115-8. 2008
    b>Candida rugosa lipase-catalysed hydrolysis of three different 2-substituted-aryloxyacetic esters was performed in aqueous buffer containing dimethyl sulphoxide and isopropanol from 0 to 80% v/v as additives, in order to obtain an ..
  44. doi Effect of oxidation level of n(+)-type mesoporous silicon surface on the adsorption and the catalytic activity of Candida rugosa lipase
    Andrea Salis
    Dipartimento di Scienze Chimiche, Università di Cagliari CSGI and CNBS, Cittadella Universitaria, S S 554 Bivio Sestu, 09042 Monserrato CA, Italy
    J Colloid Interface Sci 345:448-53. 2010
    ..Both samples were used for the adsorption of Candida rugosa lipase. A significantly higher loading was ascertained for LO-PSi (140 mg/g) compared to HO-PSi (47 mg/g)...
  45. doi Enhanced conjugation of Candida rugosa lipase onto multiwalled carbon nanotubes using reverse micelles as attachment medium and application in nonaqueous biocatalysis
    Tripti Raghavendra
    BRD School of Biosciences, Sardar Patel University, Vallabh Vidyanagar, 388 120, Gujarat, India
    Biotechnol Prog 30:828-36. 2014
    ..aqueous, nonaqueous, and reverse micelles) were scrutinized as medium for attachment of the enzyme Candida rugosa lipase (CRL) onto multiwalled carbon nanotubes (CNTs)...
  46. doi Preparation of new Calix[4]arene-immobilized biopolymers for enhancing catalytic properties of Candida rugosa lipase by sol-gel encapsulation
    Elif Ozyilmaz
    Department of Chemistry, Faculty of Science, Selcuk University, Konya, 42075, Turkey
    Appl Biochem Biotechnol 170:1871-84. 2013
    ..derivative onto cellulose and chitosan biopolymers, and the encapsulation of these calixarene biopolymers with Candida rugosa lipase within a chemical inert sol-gel supported by polycondensation with tetraethoxysilane and ..
  47. doi Assessment of activities and conformation of lipases treated with sub- and supercritical carbon dioxide
    Dawei Chen
    Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, Peoples Republic of China
    Appl Biochem Biotechnol 169:2189-201. 2013
    ..of compressed carbon dioxide treatment on the esterification activities and conformation of the three lipases Candida rugosa lipase (CRL), Pseudomonas fluorescens lipase, and Rhizopus oryzae lipase was investigated in the present work...
  48. ncbi Enzymatic interesterification of soybean oil and methyl stearate blends using lipase immobilized on magnetic Fe3O4/SBA-15 composites as a biocatalyst
    Xuezhen Zang
    School of Chemistry and Chemical Engineering, Henan University of Technology
    J Oleo Sci 63:1027-34. 2014
    ..The immobilization of Candida rugosa lipase onto the amino-functionalized Fe3O4/SBA-15 composite was investigated by using glutaraldehyde as a ..
  49. doi Maximization of bioconversion of castor oil into ricinoleic acid by response surface methodology
    Debajyoti Goswami
    Department of Chemical Engineering, Indian Institute of Technology Kharagpur, Kharagpur 721 302, India
    Bioresour Technol 100:4067-73. 2009
    ..pH, enzyme concentration (mg/g oil), and buffer concentration (g/g oil) for hydrolysis of castor oil using Candida rugosa lipase...
  50. doi Biochemical methane potential of raw and pre-treated meat-processing wastes
    A J Cavaleiro
    Institute for Biotechnology and Bioengineering, Centre of Biological Engineering, University of Minho, Campus de Gualtar, 4710 057 Braga, Portugal
    Bioresour Technol 129:519-25. 2013
    ..3 g g(-1) waste volatile solids) and lipase from Candida rugosa (10 U g(-1) fat) were applied to promote wastes hydrolysis, and the effect on BMP was evaluated...
  51. ncbi Studies of reaction parameters on synthesis of Citronellyl laurate ester via immobilized Candida rugosa lipase in organic media
    N Aziah Serri
    School of Chemical Engineering, Engineering Campus, Universiti Sains Malaysia, Seri Ampangan, 14300 Nibong Tebal, Pulau Pinang, Malaysia
    Bioprocess Biosyst Eng 29:253-60. 2006
    Immobilized Candida rugosa lipase was used for the synthesis of citronellyl laurate from citronellol and lauric acid...
  52. ncbi Efficient production of active recombinant Candida rugosa LIP3 lipase in Pichia pastoris and biochemical characterization of the purified enzyme
    Shu Wei Chang
    Institute of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung
    J Agric Food Chem 54:5831-8. 2006
    b>Candida rugosa lipase (CRL), an important industrial enzyme, possesses several different isoforms encoded by the high-identity lip gene family (lip1 to lip7)...
  53. ncbi Blocking the tunnel: engineering of Candida rugosa lipase mutants with short chain length specificity
    Jutta Schmitt
    Institute of Technical Biology, University of Stuttgart, Allmandring 31, D 70569 Stuttgart, Germany
    Protein Eng 15:595-601. 2002
    The molecular basis of chain length specificity of Candida rugosa lipase 1 was investigated by molecular modeling and site-directed mutagenesis...
  54. pmc Facilitation as Attenuating of Environmental Stress among Structured Microbial Populations
    Suzana Cláudia Silveira Martins
    Laboratory of Environmental Microbiology, Department of Biology, Sciences Center, Federal University of Ceara, Pici Campus, Block 909, 60455 760 Fortaleza, CE, Brazil
    ScientificWorldJournal 2016:5713939. 2016
    ..Pure and mixed strains of Serratia marcescens and Candida rugosa were grown in mineral culture media containing phenol...
  55. doi Biochemical properties of free and immobilized Candida rugosa lipase onto Al2O3: a comparative study
    Yesim Yesiloglu
    Department of Chemistry, Faculty of Science, Trakya University, Edirne, Turkey
    Artif Cells Blood Substit Immobil Biotechnol 39:247-51. 2011
    Lipase from Candida rugosa (CRL) was immobilized by physical adsorption onto Al(2)O(3). The immobilization yield was more than 95% during 30 min. The properties of free and immobilized enzyme were also searched and compared...
  56. ncbi Optimized growth kinetics of Pichia pastoris and recombinant Candida rugosa LIP1 production by RSM
    Shu Wei Chang
    Institute of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan
    J Mol Microbiol Biotechnol 11:28-40. 2006
    A predictive model for Pichia pastoris expression of highly active recombinant Candida rugosa LIP1 was developed by combining the Gompertz function and response surface methodology (RSM) to evaluate the effect of yeast extract ..
  57. doi Modulation of the thermostability and substrate specificity of Candida rugosa lipase1 by altering the acyl-binding residue Gly414 at the α-helix-connecting bend
    Xiaofei Zhang
    State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China
    Enzyme Microb Technol 82:34-41. 2016
    b>Candida rugosa Lipase1 (LIP1) is widely used in industrial applications. Optimizing its catalytic performance is still a challenging goal for protein engineers...
  58. ncbi Recombinant expression of the Candida rugosa lip4 lipase in Escherichia coli
    S J Tang
    Institute of Marine Biotechnology, Keelung, 20224, Taiwan
    Protein Expr Purif 20:308-13. 2000
    It is difficult to express recombinant Candida rugosa lipases (CRLs) in heterologous systems, since C. rugosa utilizes a nonuniversal serine codon CUG for leucine...
  59. doi Kinetic resolution of profens by enantioselective esterification catalyzed by Candida antarctica and Candida rugosa lipases
    Adam Sikora
    Department of Medicinal Chemistry, Collegium Medicum in Bydgoszcz, Faculty of Pharmacy, Nicolaus Copernicus University, Bydgoszcz, Poland
    Chirality 26:663-9. 2014
    ..this study was to compare the results described in the literature in the case of the influence of reaction medium, alcohol moiety, and reaction temperature on the catalytic activity of lipases from Candida antarctica and Candida rugosa.
  60. doi Systematic review and new insights into the molecular characterization of the Candida rugosa species complex
    Ana Carolina Barbosa Padovan
    Laboratorio Especial de Micologia, Disciplina de Infectologia, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brazil Electronic address
    Fungal Genet Biol 61:33-41. 2013
    Recently, Candida rugosa was characterized as a species complex comprising four taxa: C. rugosa sensu stricto, Candida pseudorugosa, Candida neorugosa and Candida mesorugosa...
  61. ncbi Candida rugosa lipase-catalyzed polyurethane degradation in aqueous medium
    Rajeeb Gautam
    Department of Chemical and Biochemical Engineering, The University of Western Ontario, London, ON, Canada
    Biotechnol Lett 29:1081-6. 2007
    b>Candida rugosa lipase (EC 3.1.1.3) was used to degrade commercially-available solid poly(ester)urethane (Impranil) in an aqueous medium under different temperature, pH, enzyme and substrate concentrations...
  62. pmc First case report of bloodstream infection due to a Candida species closely related to the novel species Candida pseudorugosa
    Constanza Giselle Taverna
    Departamento Micologia, Instituto Nacional de Enfermedades Infecciosas Dr Carlos G Malbrán, Ciudad Autonoma de Buenos Aires, Argentina
    J Clin Microbiol 50:2165-9. 2012
    Candida pseudorugosa is a novel species closely related to Candida rugosa for which only one case has been reported. We report the first case of a bloodstream infection in humans caused by a Candida sp. closely related to C. pseudorugosa...
  63. doi Properties, structure, and applications of microbial sterol esterases
    María Eugenia Vaquero
    Centro de Investigaciones Biologicas, Consejo Superior de Investigaciones Cientificas, Madrid, Spain
    Appl Microbiol Biotechnol 100:2047-61. 2016
    ..Some of the most commercially exploited cholesterol esterases are produced by Pseudomonas species and by Candida rugosa, although in the last case they are usually described and named as "high substrate versatility lipases...
  64. doi A general method for synthesizing enzyme-polymer conjugates in reverse emulsions using Pluronic as a reactive surfactant
    Xiaoling Wu
    Key Lab for Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University, Beijing 100084, China
    Chem Commun (Camb) 51:9674-7. 2015
    ..The versatility of this method was validated using horseradish peroxidase (HRP), Candida rugosa lipase (CRL) and Candida antarctica lipase B (CALB)...
  65. ncbi Investigating pH and Cu (II) effects on lipase activity and enantioselectivity via kinetic and spectroscopic methods
    Tian Wen Xu
    Laboratory of Biocatalysis and Bioprocessing, State Key Laboratory of Bioreactor Engineering, Shanghai, PR China
    Biotechnol J 1:1293-301. 2006
    For Candida rugosa lipase (CRL) catalyzed hydrolysis of racemic 1-phenethyl acetate, both the weakly acidic pH (pH 6...
  66. doi In silico and experimental characterization of chimeric Bacillus thermocatenulatus lipase with the complete conserved pentapeptide of Candida rugosa lipase
    Mostafa Hosseini
    Department of Industrial and Environmental Biotechnology, National Institute of Genetic Engineering and Biotechnology NIGEB, P O Box 14965 161, Tehran, Iran
    Appl Biochem Biotechnol 169:773-85. 2013
    ..Ala-His-Ser-Gln-Gly¹¹⁶) was replaced with similar sequences (²⁰⁷Gly-Glu-Ser-Ala-Gly²¹¹) of Candida rugosa lipase (CLR) at the nucleophilic elbow region...
  67. ncbi Enhanced activity and enantioselectivity of Candida rugosa lipase immobilized on macroporous adsorptive resins for ibuprofen resolution
    Hongwei Yu
    Chemical and Process Engineering Centre, National University of Singapore, 4 Engineering Drive 4, Singapore
    Biotechnol Lett 26:629-33. 2004
    The lipase from Candida rugosa was immobilized on three commercially available macroporous adsorptive resins for kinetic resolution of ibuprofen. One resin, CRB02, increased the enzyme activity by 50% to 0.027 g g(-1) min(-1)...
  68. doi Highly stabilized lipase in polyaniline nanofibers for surfactant-mediated esterification of ibuprofen
    Sung Gil Hong
    Department of Chemical and Biological Engineering, Korea University, Seoul 136 701, Republic of Korea
    Langmuir 30:911-5. 2014
    Lipase (LP) from Candida rugosa was immobilized and stabilized in polyaniline nanofibers (PANFs) via a three-step process of enzyme adsorption, precipitation, and cross-linking, which generates the final immobilization called "EAPC"...
  69. doi Megaporous poly(hydroxy ethylmethacrylate) based poly(glycidylmethacrylate-N-methacryloly-(L)-tryptophan) embedded composite cryogel
    Deniz Türkmen
    Department of Chemistry, Biochemistry Division, Hacettepe University, Ankara, Turkey
    Colloids Surf B Biointerfaces 130:61-8. 2015
    ..membrane having specific surface area of 195m(2)/g was used as hydrophobic matrix for adsorption of commercial Candida Rugosa lipase in a continuous system...
  70. pmc Production of 3-Hydroxypropionic Acid via the Propionyl-CoA Pathway Using Recombinant Escherichia coli Strains
    Hui Luo
    Department of Biological Science and Engineering, University of Science and Technology Beijing, Beijing, 100083, China
    PLoS ONE 11:e0156286. 2016
    ..Recombinant E. coli Ec-P overexpressing propionyl-CoA dehydrogenase (PACD, encoded by the pacd gene from Candida rugosa) under the T7 promoter produced 1.33 mM of 3-HP in a shake flask culture supplemented with 0.5% propionate...
  71. doi Biocatalytic Approach for the Synthesis of Enantiopure Acebutolol as a β₁-Selective Blocker
    Linga Banoth
    Department of Pharmaceutical Technology Biotechnology, National Institute of Pharmaceutical Education and Research NIPER, Punjab, India
    Chirality 27:382-91. 2015
    ..available lipase preparations, two enzyme preparations (Lipase A, Candida antarctica, CLEA [CAL CLEA] and Candida rugosa lipase, 62316 [CRL 62316]) act in enantioselective manner...
  72. ncbi Evaluation of medium components by Plackett-Burman statistical design for lipase production by Candida rugosa and kinetic modeling
    Aravindan Rajendran
    Biochemical Engineering Laboratory, Department of Chemical Engineering, Annamalai University, Annamalai Nagar 608 002, Tamil Nadu, India
    Sheng Wu Gong Cheng Xue Bao 24:436-44. 2008
    Lipase production by Candida rugosa was carried out in submerged fermentation. Plackett-Burman statistical experimental design was applied to evaluate the fermentation medium components...
  73. doi Extracellular enzyme production and phylogenetic distribution of yeasts in wastewater treatment systems
    Qingxiang Yang
    College of Life Sciences, Henan Normal University, Xinxiang 453007, China
    Bioresour Technol 129:264-73. 2013
    ..They were distributed in 12 identified and four unidentified genera, in which Candida rugosa (AA-M17) and an unidentified Saccharomycetales (AA-Y5), Pseudozyma sp. (PH-M15), Candida sp...
  74. ncbi [Inhibition of lipase activity by low-molecular-weight chitosan]
    E S Ostanina
    Prikl Biokhim Mikrobiol 44:38-43. 2008
    Inhibition of enzymatic activity of lipase (EC 3.1.1.3) from the fungus Candida rugosa and wheat (Triticum aestivum L.) germ by low-molecular-weight chitosan with an average molecular weight of 5...
  75. doi Design of biocompatible immobilized Candida rugosa lipase with potential application in food industry
    Jovana Trbojević Ivić
    Innovation Center, Faculty of Chemistry, University of Belgrade, 11000, Belgrade, Serbia
    J Sci Food Agric 96:4281-7. 2016
    Biocatalysts are a promising alternative for the production of natural flavor compounds. Candida rugosa lipase (CRL) is a particularly important biocatalyst owing to its remarkable efficiency in both hydrolysis and synthesis...
  76. doi Microbiological and chemical characteristics of tarubá, an indigenous beverage produced from solid cassava fermentation
    Cíntia L Ramos
    Department of Biology, Federal University of Lavras, 37 200 000 Lavras, MG, Brazil
    Food Microbiol 49:182-8. 2015
    ..Torulaspora delbrueckii was the dominant yeast species. Yeast isolates Pichia exigua, Candida rugosa, T...
  77. doi Improving catalytic hydrolysis reaction efficiency of sol-gel-encapsulated Candida rugosa lipase with magnetic β-cyclodextrin nanoparticles
    Elif Ozyilmaz
    Department of Chemistry, Selcuk University, 42075 Konya, Turkey
    Colloids Surf B Biointerfaces 113:182-9. 2014
    ..Then, the β-cyclodextrin-grafted magnetic nanoparticles were encapsulated with Candida rugosa lipase in sol-gel matrices using alkoxysilane precursors...
  78. ncbi Optimization of medium composition for lipase production by Candida rugosa NCIM 3462 using response surface methodology
    Aravindan Rajendran
    Biochemical Engineering Laboratory, Department of Chemical Engineering, Annamalai University, Annamalai Nagar 608 002, Tamil Nadu, India
    Can J Microbiol 53:643-55. 2007
    ..optimization approach using statistical design of experiments was employed to enhance the lipase production by Candida rugosa in submerged batch fermentation...
  79. ncbi Carotenol fatty acid esters: easy substrates for digestive enzymes?
    Dietmar E Breithaupt
    Universitat Hohenheim, Institut fur Lebensmittelchemie, Garbenstr 28, 70593, Stuttgart, Germany
    Comp Biochem Physiol B Biochem Mol Biol 132:721-8. 2002
    ..As reference enzyme a yeast lipase from Candida rugosa was applied...
  80. pmc Molecular identification and antifungal susceptibility testing of clinical isolates of the Candida rugosa species complex and proposal of the new species Candida neorugosa
    Katihuska Paredes
    Unitat de Microbiologia, Facultat de Medicina i Ciencies de la Salut, IISPV, Universitat Rovira i Virgili, Reus, Tarragona, Spain
    J Clin Microbiol 50:2397-403. 2012
    b>Candida rugosa is a poorly known fungal species occasionally involved in human infections...
  81. doi Mechanistic investigations of lipase-catalyzed degradation of polycarbonate in organic solvents
    Trishul Artham
    Department of Biotechnology, Indian Institute of Technology Madras, S P Road, Adyar, Chennai 600036, India
    Enzyme Microb Technol 48:71-9. 2011
    ..bisphenol-A carbonate) (BPAPC), was carried out using three different lipases from Candida antarctica (CAL), Candida rugosa (CRL) and porcine pancreas (PPL) in water-miscible (tetrahydrofuran) and water-immiscible (chloroform) ..
  82. ncbi Structure and conformational flexibility of Candida rugosa lipase
    M Cygler
    Biotechnology Research Institute, National Research Council of Canada, 6100 Royalmount Avenue, Montreal, Quebec, Canada
    Biochim Biophys Acta 1441:205-14. 1999
    ..The structural studies of Candida rugosa lipase summarized here have addressed many facets of interfacial catalysis...
  83. ncbi Lipase-catalyzed acidolysis of menhaden oil with conjugated linoleic acid: effect of water content
    Carlos F Torres
    Department of Chemical Engineering, University of Wisconsin Madison, 1415 Engineering Dr, Madison, WI 53706, USA
    Biotechnol Bioeng 78:509-16. 2002
    The effect of the water content on the lipase-catalyzed (Candida rugosa) interesterification (acidolysis) of menhaden oil with conjugated linoleic acid was studied for amounts of added water ranging from 0-4% (w/w)...
  84. doi Biological treatment of olive mill wastewater by non-conventional yeasts
    Cristiana Gonçalves
    IBB Institute for Biotechnology and Bioengineering, Centre of Biological Engineering, University of Minho, Campus de Gualtar, 4710 057 Braga, Portugal
    Bioresour Technol 100:3759-63. 2009
    ..Studies of OMW consumption were carried out in batch cultures of Candida rugosa, Candida cylindracea and Yarrowia lipolytica...
  85. ncbi Pre-treatment of high oil and grease pet food industrial wastewaters using immobilized lipase hydrolyzation
    Jeganaesan Jeganathan
    Department of Chemical and Biochemical Engineering, University of Western Ontario, London, Ontario N6A 5B9, Canada
    J Hazard Mater 137:121-8. 2006
    ..In this study, the hydrolysis of O&G originating from pet food industrial wastewater was evaluated. Candida rugosa lipase was immobilized in calcium alginate beads and applied in the hydrolysis experiment...
  86. doi Novel magnetic microspheres of P (GMA-b-HEMA): preparation, lipase immobilization and enzymatic activity in two phases
    Yanjun Cui
    College of Chemistry and Chemical Engineering, State Key Laboratory of Applied Organic Chemistry, Institute of Biochemical Engineering and Environmental Technology, Lanzhou University, Lanzhou 730000, China
    Appl Microbiol Biotechnol 95:147-56. 2012
    ..on their reactive functional group and excellent biocompatibility which were suitable for immobilization of Candida rugosa lipase (CRL)...
  87. ncbi Fabrication and application of enzyme-incorporated peptide nanotubes
    Lingtao Yu
    Department of Chemistry and Biochemistry at Hunter College and the Graduate Center, The City University of New York, New York, New York 10021, USA
    Bioconjug Chem 16:1484-7. 2005
    ..In this report, we examined peptide nanotubes as supports for enzymes. When a model enzyme, Candida rugosa lipase, was encapsulated in peptide nanotubes, the catalytic activity of nanotube-bound lipases was increased ..
  88. ncbi Behavior of silica aerogel networks as highly porous solid solvent media for lipases in a model transesterification reaction
    H El Rassy
    Institut de Recherches sur la Catalyse, UPR CNRS 5401, 2 avenue Albert Einstein, 69626 Villeurbanne Cedex, France
    Chembiochem 4:203-10. 2003
    ..Two types of lipases from Candida rugosa and Burkholderia cepacia were homogeneously dispersed in wet gel precursors before gelation...
  89. ncbi Production of 3-hydroxypropionic acid from acrylic acid by newly isolated rhodococcus erythropolis LG12
    Sang Hyun Lee
    Corporate R and D, LG Chem Research Park, 104 1 Moonji dong, Yuseong Gu, Daejeon 305 380, Korea
    J Microbiol Biotechnol 19:474-81. 2009
    ..rhodochrous, R. equi, R. rubber, Candida rugosa, and Bacillus cereus. The effect of the culture conditions of R...
  90. pmc Secondary structure, conformational stability and glycosylation of a recombinant Candida rugosa lipase studied by Fourier-transform infrared spectroscopy
    Antonino Natalello
    Dipartimento di Biotecnologie e Bioscienze, Universita degli Studi di Milano Bicocca, Piazza della Scienza 2, 20126 Milano, Italy
    Biochem J 385:511-7. 2005
    The secondary structure of lipase 1 from Candida rugosa, a model system for large monomeric enzymes, has been studied by FTIR (Fourier-transform infrared) spectroscopy in water and 2H2O...
  91. ncbi Antimicrobial and anti-lipase activity of quercetin and its C2-C16 3-O-acyl-esters
    Maria Teresa Gatto
    Department of Pharmacology of Natural Substances and General Physiology, University of Rome La Sapienza, P le Aldo Moro 5, 00185, Rome, Italy
    Bioorg Med Chem 10:269-72. 2002
    ..Finally, we described an interesting inhibitory activity on Candida rugosa lipase by Q (IC(16)=10(-4) M) and its esters (3-O-acylquercetines) which, in vivo, could play an important ..
  92. ncbi Esterase catalysis of substrate vapour: enzyme activity occurs at very low hydration
    Penelope A Lind
    Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA
    Biochim Biophys Acta 1702:103-10. 2004
    ..The influence of enzyme hydration on the hydrolysis of substrate by Candida rugosa Lipase B and pig liver esterase was investigated...
  93. ncbi Stereochemistry of a diastereoisomeric amphiphile and the species of the lipase influence enzyme activity in the transesterification catalyzed by a lipase-co-lyophilizate with the amphiphile in organic media
    Yurie Mine
    Department of Applied Chemistry and Chemical Engineering, Faculty of Engineering, Yamaguchi University, 2 16 1 Tokiwadai, Ube 755 8611, Japan
    Biotechnol Lett 25:1863-7. 2003
    Modified Candida rugosa and Pseudomonas cepacia lipase (CRL and PCL) were co-lyophilized with two pairs of synthetic diastereoisomeric amphiphiles, D- and L-2-(3-[bis-[3-(2,3,4,5,6-pentahydroxy-hexanoylamino)-propyl]-carbamoyl]-..
  94. ncbi Effect of acyl chain length and branching on the enantioselectivity of Candida rugosa lipase in the kinetic resolution of 4-(2-difluoromethoxyphenyl)-substituted 1,4-dihydropyridine 3,5-diesters
    Arkadij Sobolev
    Laboratory of Organic Chemistry, Wageningen University, Dreijenplein 8, 6703 HB Wageningen, The Netherlands
    J Org Chem 67:401-10. 2002
    ..were synthesized and subjected to Candida rugosa lipase (CRL) catalyzed hydrolysis in wet diisopropyl ether...
  95. ncbi Reversible and strong immobilization of proteins by ionic exchange on supports coated with sulfate-dextran
    Manuel Fuentes
    Departamento de Biocatalisis, Instituto de Catalisis CSIC, Campus UAM, Cantoblanco, 28049 Madrid, Spain
    Biotechnol Prog 20:1134-9. 2004
    ..strain T2, lipases from Candida antarctica A and B, Candida rugosa, Rhizomucor miehei, and Rhyzopus oryzae and bovine pancreas trypsin and chymotrypsin) have been immobilized on ..
  96. pmc Preparation of coaxial-electrospun poly[bis(p-methylphenoxy)]phosphazene nanofiber membrane for enzyme immobilization
    Shu Gen Wang
    Key Laboratory of Eco Textile, Ministry of Education, Jiangnan University, Wuxi 214122, China
    Int J Mol Sci 13:14136-48. 2012
    ..Lipase from Candida rugosa was immobilized on the nanofiber membrane by adsorption...
  97. ncbi Codon optimization of Candida rugosa lip1 gene for improving expression in Pichia pastoris and biochemical characterization of the purified recombinant LIP1 lipase
    Shu Wei Chang
    Institute of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung 202, Taiwan
    J Agric Food Chem 54:815-22. 2006
    An important industrial enzyme, Candida rugosa lipase (CRL) possesses several different isoforms encoded by the lip gene family (lip1-lip7), in which the recombinant LIP1 is the major form of the CRL multigene family...
  98. doi Enhancement of the activity and enantioselectivity of lipase by sol-gel encapsulation immobilization onto β-cyclodextrin-based polymer
    Elif Yilmaz
    Department of Chemistry, Faculty of Science, Selcuk University, Konya, Turkey
    Appl Biochem Biotechnol 166:1927-40. 2012
    b>Candida rugosa lipase was encapsulated within a chemically inert sol-gel support prepared by polycondensation with tetraethoxysilane and octyltriethoxysilane in the presence of β-cyclodextrin-based polymer...
  99. ncbi Lipase-catalyzed esterification of 2-monoricinolein for 1,2 (2,3)-diricinolein synthesis
    Charlotta Turner
    Western Regional Research Center, U S Department of Agriculture, Albany, California 94710, USA
    Lipids 41:77-83. 2006
    ..esterification reaction, we investigated these five lipases plus Pseudomonas cepacia, Penicillium roquefortii, Candida rugosa, and Pseudomonas fluorescence...
  100. doi PCR-SSCP-based reconstruction of the original fungal flora of heat-processed meat products
    Samart Dorn-In
    Chair of Animal Hygiene, WZW, TUM, Weihenstephaner Berg 3, 85354 Freising, Germany
    Int J Food Microbiol 162:71-81. 2013
    ..g. Alternaria alternata, Aureobasidium pullulans, Candida rugosa, C. tropicalis, C...
  101. doi Lipases efficiently stearate and cutinases acetylate the surface of arabinoxylan films
    A M Stepan
    WWSC, Wallenberg Wood Science Center, Chalmers University of Technology, Kemivagen 10, SE 412 96 Goteborg, Sweden
    J Biotechnol 167:16-23. 2013
    ..analytical techniques (FT-IR, TOF-SIMS, ESCA, CA) show that lipases from Mucor javanicus, Rhizopus oryzae and Candida rugosa successfully surface stearate AX films and that a cutinase from Fusarium solani pisi surface acetylates these ..

Research Grants4

  1. PROTEIN DRUG DELIVERY BASED ON STABILIZED PROTEIN
    ALEXEY MARGOLIN; Fiscal Year: 2000
    ..In the Phase I, we developed a stable, active formulation of lipase from Candida rugosa, TheraCLEC-lipase, for use in the treatment of pancreatic insufficiency in cystic fibrosis...
  2. NRG1 Regulation of Candida albicans Virulence
    Jose Lopez Ribot; Fiscal Year: 2004
    ..albicans virulence and ii) to identify downstream targets of Nrg1p under both planktonic and biofilm growing conditions. ..
  3. Small molecule inhibitors of Candida albicans biofilm formation
    Jose Lopez Ribot; Fiscal Year: 2008
    ..albicans to form biofilms, a substantial reduction in morbidity, mortality and extended hospital stay can be achieved while simultaneously reducing healthcare costs. [unreadable] [unreadable] [unreadable]..
  4. Host Immunity and Virulence in Candida albicans Pathogenesis
    Jose Lopez Ribot; Fiscal Year: 2009
    ..Results are likely to lead to the development of new immune-based strategies for the prevention and treatment of systemic candidiasis that are urgently needed. ..

Patents17

  1. BIOLOGICAL METHODS FOR PREPARING A FATTY DICARBOXYLIC ACID
    Patent Number: JP2016501041-A; Date:2016-01-18
  2. A method for producing an L-amino acid
    Patent Number: WO2011013707-A; Date:2011-02-03
  3. Recombinant candida rugosa lipases
    Patent Number: EP1288294-A2; Date:2003-03-05
  4. Highly conserved genes and their use to generate probes and primers for detection of microorganisms
    Patent Number: WO0123604-A2; Date:2001-04-05
  5. Process for the production of a fine chemical
    Patent Number: WO2008034648-A1; Date:2008-03-27
  6. A method for producing an L-amino acid
    Patent Number: WO2009093703-A; Date:2009-07-30
  7. A method for producing an L-amino acid
    Patent Number: WO2009011354-A; Date:2009-01-22
  8. Method of producing L-amino acid
    Patent Number: KR1020100120663-A; Date:2010-11-16
  9. RECOMBINANT CANDIDA RUGOSA LIPASES
    Patent Number: JP2005185291-A; Date:2005-07-14
  10. RECOMBINANT CANDIDA RUGOSA LIPASES
    Patent Number: JP2005185290-A; Date:2005-07-14
  11. Method for Detecting and Identifying Candida Species
    Patent Number: JP2012500019-A; Date:2012-01-05
  12. METHOD FOR PRODUCING FATTY ACIDS OR DERIVATIVES THEREOF FROM OIL PLANT
    Patent Number: WO9603511-A2; Date:1996-02-08
  13. RECOMBINANT CANDIDA RUGOSA LIPASES
    Patent Number: JP2003144162-A; Date:2003-05-20
  14. Process for the production of a fine chemical
    Patent Number: EP2090662-A2; Date:2009-08-19
  15. Method for identifying and detecting Candida yeast with II type topoisomerase gene as indication
    Patent Number: JP2002153276-A; Date:2002-05-28
  16. Nucleic acid probes for detecting candida species
    Patent Number: JP2001512035-A; Date:2001-08-21
  17. Nucleic acids probes for detection of yeast and fungal species
    Patent Number: WO2008072217-A2; Date:2008-06-19