sea cucumbers

Summary

Alias: sea cucumbers, holothurians, Holothuroidea, Holothurioidea

Top Publications

  1. Yu H, Gao Q, Dong S, Zhou J, Ye Z, Lan Y. Effects of dietary n-3 highly unsaturated fatty acids (HUFAs) on growth, fatty acid profiles, antioxidant capacity and immunity of sea cucumber Apostichopus japonicus (Selenka). Fish Shellfish Immunol. 2016;54:211-9 pubmed publisher
    ..growth rates, fatty acid profiles, activities and gene expression of antioxidative enzymes and lysozyme of the sea cucumbers that were fed with the 5 experimental diets were determined...
  2. Vinnitskiy D, Ustyuzhanina N, Dmitrenok A, Shashkov A, Nifantiev N. Synthesis and NMR analysis of model compounds related to fucosylated chondroitin sulfates: GalNAc and Fuc(1 ? 6)GalNAc derivatives. Carbohydr Res. 2017;438:9-17 pubmed publisher
    ..were synthesized as model compounds representing the fragments of fucosylated chondroitin sulfates (FCS) from sea cucumbers. Per-O-acetylated 2-deoxy-2-N-phthalimido-D-glucopyranose was used as a key precursor for the preparation of ..
  3. Liu X, Hao J, Shan X, Zhang X, Zhao X, Li Q, et al. Antithrombotic activities of fucosylated chondroitin sulfates and their depolymerized fragments from two sea cucumbers. Carbohydr Polym. 2016;152:343-350 pubmed publisher
    ..Our results proposed a new point of view to understand the structure-activity relationship of FCS as alternative agents. ..
  4. Brown A, Wright R, Mevenkamp L, Hauton C. A comparative experimental approach to ecotoxicology in shallow-water and deep-sea holothurians suggests similar behavioural responses. Aquat Toxicol. 2017;191:10-16 pubmed publisher
    ....
  5. Correia da Silva M, Sousa E, Pinto M, Kijjoa A. Anticancer and cancer preventive compounds from edible marine organisms. Semin Cancer Biol. 2017;46:55-64 pubmed publisher
    ..eel and also fish protein hydrolysates), mollusks (mussel, oyster, clams and abalone), as well as from sea cucumbers on the in vivo/in vitro anticancer/antitumor activities can, in part, support the health benefits of these ..
  6. Sun L, Sun J, Xu Q, Li X, Zhang L, Yang H. Metabolic responses to intestine regeneration in sea cucumbers Apostichopus japonicus. Comp Biochem Physiol Part D Genomics Proteomics. 2017;22:32-38 pubmed publisher
    b>Sea cucumbers are excellent models for studying organ regeneration due to their striking capacity to regenerate most of their viscera after evisceration...
  7. Aminin D, Pislyagin E, Astashev M, Es kov A, Kozhemyako V, Avilov S, et al. Glycosides from edible sea cucumbers stimulate macrophages via purinergic receptors. Sci Rep. 2016;6:39683 pubmed publisher
    Since ancient times, edible sea cucumbers have been considered a jewel of the seabed and used in Asian folk medicine for stimulation of resistance against different diseases...
  8. Mjobo S, Thandar A. A new genus and a new species in the sea cucumber subfamily Colochirinae (Echinodermata: Holothuroidea: Dendrochirotida: Cucumariidae) in the Mediterranean Sea. Zootaxa. 2016;4189:zootaxa.4189.1.8 pubmed publisher
    ..O. brunneus, O. planci and O. lacteus, but the soft nature of the body wall, shallow quadrilocular instead of deep trilocular baskets, and the presence of large knobbed plates in the anal region precludes its inclusion in this genus. ..
  9. Wang X, Sun Y, Wang L, Li X, Qu K, Xu Y. Synbiotic dietary supplement affects growth, immune responses and intestinal microbiota of Apostichopus japonicus. Fish Shellfish Immunol. 2017;68:232-242 pubmed publisher
    ..b>Sea cucumbers were given a control diet (non-supplemented), pro diet (basal diet plus 1 × 109 cfu (g diet)<..
  10. Yu H, Zhang C, Gao Q, Dong S, Ye Z, Tian X. Impact of water temperature on the growth and fatty acid profiles of juvenile sea cucumber Apostichopus japonicus (Selenka). J Therm Biol. 2016;60:155-61 pubmed publisher
    ..b>Sea cucumbers with similar size (4.02±0.11g) were cultured for 8 weeks at 14°C, 18°C, 22°C and 26°C, respectively...

Locale

Detail Information

Publications72

  1. Yu H, Gao Q, Dong S, Zhou J, Ye Z, Lan Y. Effects of dietary n-3 highly unsaturated fatty acids (HUFAs) on growth, fatty acid profiles, antioxidant capacity and immunity of sea cucumber Apostichopus japonicus (Selenka). Fish Shellfish Immunol. 2016;54:211-9 pubmed publisher
    ..growth rates, fatty acid profiles, activities and gene expression of antioxidative enzymes and lysozyme of the sea cucumbers that were fed with the 5 experimental diets were determined...
  2. Vinnitskiy D, Ustyuzhanina N, Dmitrenok A, Shashkov A, Nifantiev N. Synthesis and NMR analysis of model compounds related to fucosylated chondroitin sulfates: GalNAc and Fuc(1 ? 6)GalNAc derivatives. Carbohydr Res. 2017;438:9-17 pubmed publisher
    ..were synthesized as model compounds representing the fragments of fucosylated chondroitin sulfates (FCS) from sea cucumbers. Per-O-acetylated 2-deoxy-2-N-phthalimido-D-glucopyranose was used as a key precursor for the preparation of ..
  3. Liu X, Hao J, Shan X, Zhang X, Zhao X, Li Q, et al. Antithrombotic activities of fucosylated chondroitin sulfates and their depolymerized fragments from two sea cucumbers. Carbohydr Polym. 2016;152:343-350 pubmed publisher
    ..Our results proposed a new point of view to understand the structure-activity relationship of FCS as alternative agents. ..
  4. Brown A, Wright R, Mevenkamp L, Hauton C. A comparative experimental approach to ecotoxicology in shallow-water and deep-sea holothurians suggests similar behavioural responses. Aquat Toxicol. 2017;191:10-16 pubmed publisher
    ....
  5. Correia da Silva M, Sousa E, Pinto M, Kijjoa A. Anticancer and cancer preventive compounds from edible marine organisms. Semin Cancer Biol. 2017;46:55-64 pubmed publisher
    ..eel and also fish protein hydrolysates), mollusks (mussel, oyster, clams and abalone), as well as from sea cucumbers on the in vivo/in vitro anticancer/antitumor activities can, in part, support the health benefits of these ..
  6. Sun L, Sun J, Xu Q, Li X, Zhang L, Yang H. Metabolic responses to intestine regeneration in sea cucumbers Apostichopus japonicus. Comp Biochem Physiol Part D Genomics Proteomics. 2017;22:32-38 pubmed publisher
    b>Sea cucumbers are excellent models for studying organ regeneration due to their striking capacity to regenerate most of their viscera after evisceration...
  7. Aminin D, Pislyagin E, Astashev M, Es kov A, Kozhemyako V, Avilov S, et al. Glycosides from edible sea cucumbers stimulate macrophages via purinergic receptors. Sci Rep. 2016;6:39683 pubmed publisher
    Since ancient times, edible sea cucumbers have been considered a jewel of the seabed and used in Asian folk medicine for stimulation of resistance against different diseases...
  8. Mjobo S, Thandar A. A new genus and a new species in the sea cucumber subfamily Colochirinae (Echinodermata: Holothuroidea: Dendrochirotida: Cucumariidae) in the Mediterranean Sea. Zootaxa. 2016;4189:zootaxa.4189.1.8 pubmed publisher
    ..O. brunneus, O. planci and O. lacteus, but the soft nature of the body wall, shallow quadrilocular instead of deep trilocular baskets, and the presence of large knobbed plates in the anal region precludes its inclusion in this genus. ..
  9. Wang X, Sun Y, Wang L, Li X, Qu K, Xu Y. Synbiotic dietary supplement affects growth, immune responses and intestinal microbiota of Apostichopus japonicus. Fish Shellfish Immunol. 2017;68:232-242 pubmed publisher
    ..b>Sea cucumbers were given a control diet (non-supplemented), pro diet (basal diet plus 1 × 109 cfu (g diet)<..
  10. Yu H, Zhang C, Gao Q, Dong S, Ye Z, Tian X. Impact of water temperature on the growth and fatty acid profiles of juvenile sea cucumber Apostichopus japonicus (Selenka). J Therm Biol. 2016;60:155-61 pubmed publisher
    ..b>Sea cucumbers with similar size (4.02±0.11g) were cultured for 8 weeks at 14°C, 18°C, 22°C and 26°C, respectively...
  11. Li C, Zhao M, Zhang C, Zhang W, Zhao X, Duan X, et al. miR210 modulates respiratory burst in Apostichopus japonicus coelomocytes via targeting Toll-like receptor. Dev Comp Immunol. 2016;65:377-381 pubmed publisher
    ..ancient immune system with the recognition the economic values of several species in this phylum, especially sea cucumbers. Here, we reported a study in the innate immunity of a sea cucumber species (Apostichopus japonicus) in ..
  12. Linchangco G, Foltz D, Reid R, Williams J, Nodzak C, Kerr A, et al. The phylogeny of extant starfish (Asteroidea: Echinodermata) including Xyloplax, based on comparative transcriptomics. Mol Phylogenet Evol. 2017;115:161-170 pubmed publisher
    ..classes (Asteroidea and Ophiuroidea) and a similar relationship between echinozoan classes (Echinoidea and Holothuroidea)...
  13. Sun L, Xu D, Xu Q, Sun J, Xing L, Zhang L, et al. iTRAQ reveals proteomic changes during intestine regeneration in the sea cucumber Apostichopus japonicus. Comp Biochem Physiol Part D Genomics Proteomics. 2017;22:39-49 pubmed publisher
    b>Sea cucumbers have a striking capacity to regenerate most of their viscera after evisceration, which has drawn the interest of many researchers...
  14. Valcarcel J, Novoa Carballal R, Pérez Martín R, Reis R, Vazquez J. Glycosaminoglycans from marine sources as therapeutic agents. Biotechnol Adv. 2017;35:711-725 pubmed publisher
    ..Also displaying antiviral and anti-metastatic properties, a rare CS with fucosylated branches isolated from sea cucumbers is an anticoagulant and anti-inflammatory agent...
  15. Yun S, Shin S, Stonik V, Park J. Ceramide as a Target of Marine Triterpene Glycosides for Treatment of Human Myeloid Leukemia. Mar Drugs. 2016;14: pubmed
    ..role of ceramide in treating leukemia, and the antitumor activity, related to ceramide metabolism, of some marine metabolites, particularly stichoposides, triterpene glycosides extracted from sea cucumbers of the family Stichopodiidae.
  16. Zhou X, Wang H, Cui J, Qiu X, Chang Y, Wang X. Transcriptome analysis of tube foot and large scale marker discovery in sea cucumber, Apostichopus japonicus. Comp Biochem Physiol Part D Genomics Proteomics. 2016;20:41-49 pubmed publisher
    ..factors (MBL, VLRA, AjC3, MyD88, CFB), skin pigmentation (MITF), candidate regeneration factor (TRP) and holothurians autolysis-related factor (CL)...
  17. Williamson J, Byrnes E, Clark J, Connolly D, Schiller S, Thompson J, et al. Ecological impacts and management implications of reef walking on a tropical reef flat community. Mar Pollut Bull. 2017;114:742-750 pubmed publisher
    ..A manipulative experiment showed handling holothurians on reef walks had lasting negative impacts...
  18. Tunca E, Aydin M, Şahin Ü. Interactions and accumulation differences of metal(loid)s in three sea cucumber species collected from the Northern Mediterranean Sea. Environ Sci Pollut Res Int. 2016;23:21020-21031 pubmed
    ..The body walls and guts of these holothurians were examined in terms of interactions of 10 metals (iron (Fe), copper (Cu), manganese (Mn), zinc (Zn), ..
  19. Miller A, Kerr A, Paulay G, Reich M, Wilson N, Carvajal J, et al. Molecular phylogeny of extant Holothuroidea (Echinodermata). Mol Phylogenet Evol. 2017;111:110-131 pubmed publisher
    b>Sea cucumbers (Holothuroidea) are a morphologically diverse, ecologically important, and economically valued clade of echinoderms; however, the understanding of the overall systematics of the group remains controversial...
  20. Mu C, Wang R, Li T, Li Y, Tian M, Jiao W, et al. Long Non-Coding RNAs (lncRNAs) of Sea Cucumber: Large-Scale Prediction, Expression Profiling, Non-Coding Network Construction, and lncRNA-microRNA-Gene Interaction Analysis of lncRNAs in Apostichopus japonicus and Holothuria glaberrima During LPS Cha. Mar Biotechnol (NY). 2016;18:485-99 pubmed publisher
    ..1 [TLR1] and transglutaminase-1 [TGM1]) in response to LPS challenge and radial organ complex regeneration in sea cucumbers. Overall, this pioneer systematic identification, annotation, and characterization of lncRNAs in echinoderm ..
  21. Marques J, Vilanova E, Mourao P, Fernàndez Busquets X. Marine organism sulfated polysaccharides exhibiting significant antimalarial activity and inhibition of red blood cell invasion by Plasmodium. Sci Rep. 2016;6:24368 pubmed publisher
    ..Here, we have explored the antiplasmodial capacity of heparin-like sulfated polysaccharides from the sea cucumbers Ludwigothurea grisea and Isostichopus badionotus, from the red alga Botryocladia occidentalis, and from the ..
  22. Xing L, Sun L, Liu S, Li X, Zhang L, Yang H. IBT-based quantitative proteomics identifies potential regulatory proteins involved in pigmentation of purple sea cucumber, Apostichopus japonicus. Comp Biochem Physiol Part D Genomics Proteomics. 2017;23:17-26 pubmed publisher
    b>Sea cucumbers are an important economic species and exhibit high yield value among aquaculture animals. Purple sea cucumbers are very rare and beautiful and have stable hereditary patterns...
  23. Zhu A, Chen M, Zhang X, Storey K. Gene structure, expression, and DNA methylation characteristics of sea cucumber cyclin B gene during aestivation. Gene. 2016;594:82-88 pubmed publisher
    ..DNA methylation characteristics of cyclin B were analyzed in non-aestivation and deep-aestivation stages of sea cucumbers. We found that the cyclin B promoter contains a CpG island, three CCAAT-boxes and three cell cycle gene ..
  24. Wang J, Ren T, Wang F, Han Y, Liao M, Jiang Z, et al. Effects of dietary cadmium on growth, antioxidants and bioaccumulation of sea cucumber (Apostichopus japonicus) and influence of dietary vitamin C supplementation. Ecotoxicol Environ Saf. 2016;129:145-53 pubmed publisher
    ..In addition, the potential protective effects of vitamin C (L-ascorbic acid, AsA) against the effects of Cd on sea cucumbers were investigated...
  25. Ma S, Sun Y, Wang F, Mi R, Wen Z, Li X, et al. Effects of tussah immunoreactive substances on growth, immunity, disease resistance against Vibrio splendidus and gut microbiota profile of Apostichopus japonicus. Fish Shellfish Immunol. 2017;63:471-479 pubmed publisher
    ..The specific growth rate (SGR) of TIS-fed sea cucumbers was significantly enhanced, whereas no significant difference in SGR was observed between those soaked in ..
  26. Chai T, Law Y, Wong F, Kim S. Enzyme-Assisted Discovery of Antioxidant Peptides from Edible Marine Invertebrates: A Review. Mar Drugs. 2017;15: pubmed publisher
    Marine invertebrates, such as oysters, mussels, clams, scallop, jellyfishes, squids, prawns, sea cucumbers and sea squirts, are consumed as foods. These edible marine invertebrates are sources of potent bioactive peptides...
  27. Montgomery E, Hamel J, Mercier A. Patterns and Drivers of Egg Pigment Intensity and Colour Diversity in the Ocean: A Meta-Analysis of Phylum Echinodermata. Adv Mar Biol. 2017;76:41-104 pubmed publisher
    ..Finally, green occurs chiefly in the classes Holothuroidea and Ophiuroidea, orange in Asteroidea, yellow in Echinoidea, and brown in Holothuroidea...
  28. Li Z, Li X, Zhang J, Wang X, Wang L, Cao Z, et al. Use of phages to control Vibrio splendidus infection in the juvenile sea cucumber Apostichopus japonicus. Fish Shellfish Immunol. 2016;54:302-11 pubmed publisher
    ..In an in vivo performance trial, 360 sea cucumbers (23 ± 2 g) were randomly assigned to 1 of 6 treatments...
  29. Samyn Y, Vandenspiegel D. Sublittoral and bathyal sea cucumbers (Echinodermata: Holothuroidea) from the Northern Mozambique Channel with description of six new species. Zootaxa. 2016;4196:zootaxa.4196.4.1 pubmed publisher
    ..Our findings demonstrate how ignorant we are about the poorly explored habitats of our planet and therefore stress the urgent need for more explorations to such regions. ..
  30. Pereira T, Mattar L, Pereira E, Merçon J, da Silva A, Cruz Z. Effects of Tin on Enzyme Activity in Holothuria grisea (Echinodermata: Holothuroidea). Bull Environ Contam Toxicol. 2017;98:607-611 pubmed publisher
    ..These results indicate that H. grisea is a potential bioindicator for seascape habitat monitoring programs, as its biochemical markers show sensitivity to trace elements that can indicate a rise in pollution levels. ..
  31. Kamyab E, Kühnhold H, Novais S, Alves L, Indriana L, Kunzmann A, et al. Effects of thermal stress on the immune and oxidative stress responses of juvenile sea cucumber Holothuria scabra. J Comp Physiol B. 2017;187:51-61 pubmed publisher
    ..Here, the main goal was to study the response of sea cucumbers to temperature stress, assessing sub-organismal alterations and acclimation capacities of juveniles to ..
  32. Li J, Li S, Yan L, Ding T, Linhardt R, Yu Y, et al. Fucosylated chondroitin sulfate oligosaccharides exert anticoagulant activity by targeting at intrinsic tenase complex with low FXII activation: Importance of sulfation pattern and molecular size. Eur J Med Chem. 2017;139:191-200 pubmed publisher
    Fucosylated chondroitin sulfates (fCSs) are structurally unusual glycosaminoglycans isolated from sea cucumbers that exhibit potent anticoagulant activity...
  33. Xia J, Ren C, Yu Z, Wu X, Qian J, Hu C. Complete mitochondrial genome of the sandfish Holothuria scabra (Holothuroidea, Holothuriidae). Mitochondrial DNA A DNA Mapp Seq Anal. 2016;27:4174-4175 pubmed
    ..Comparative analyses between H. scabra and other holothurians revealed three new findings: (1) the mitogenome of H...
  34. Lv Z, Zhang Z, Wei Z, Li C, Shao Y, Zhang W, et al. HMGB3 modulates ROS production via activating TLR cascade in Apostichopus japonicus. Dev Comp Immunol. 2017;77:128-137 pubmed publisher
    ..5% in the AjHMGB3 overexpressed group and depressed by 28.2% in the AjHMGB3 knock-down group. Our present findings collectively suggested that AjHMGB3 acted as an NF-?B activator and produced ROS production in sea cucumbers.
  35. Zhang E, Dong S, Wang F, Tian X, Gao Q. Effects of l-tryptophan on the growth, intestinal enzyme activities and non-specific immune response of sea cucumber (Apostichopus japonicus Selenka) exposed to crowding stress. Fish Shellfish Immunol. 2018;75:158-163 pubmed publisher
    ..response of sea cucumber (Apostichopus japonicus Selenka) exposed to crowding stress, four density groups of sea cucumbers (i.e...
  36. Ustyuzhanina N, Bilan M, Dmitrenok A, Tsvetkova E, Shashkov A, Stonik V, et al. Structural characterization of fucosylated chondroitin sulfates from sea cucumbers Apostichopus japonicus and Actinopyga mauritiana. Carbohydr Polym. 2016;153:399-405 pubmed publisher
    ..Small portions of Fucp4S units attached to O-3 of GlcA were also found in both polysaccharides. Moreover, in a structure of AM the presence of Fucp3S residues linked to O-6 of GalNAc were determined using the data of NMR spectra. ..
  37. Mo J, Prévost S, Blowes L, Egertová M, Terrill N, Wang W, et al. Interfibrillar stiffening of echinoderm mutable collagenous tissue demonstrated at the nanoscale. Proc Natl Acad Sci U S A. 2016;113:E6362-E6371 pubmed
    The mutable collagenous tissue (MCT) of echinoderms (e.g., sea cucumbers and starfish) is a remarkable example of a biological material that has the unique attribute, among collagenous tissues, of being able to rapidly change its ..
  38. Li S, Li J, Zhi Z, Hu Y, Ge J, Ye X, et al. 4-O-Sulfation in sea cucumber fucodians contribute to reversing dyslipidiaemia caused by HFD. Int J Biol Macromol. 2017;99:96-104 pubmed publisher
    Fucodians extracted from sea cucumbers (SC-FUCs) possess linear chains with uniform repeating units. Sulfation patterns endow SC-FUCs unique structures and bioactivity...
  39. Marquet N, Hubbard P, Da Silva J, Afonso J, Canario A. Chemicals released by male sea cucumber mediate aggregation and spawning behaviours. Sci Rep. 2018;8:239 pubmed publisher
    ..The identification of pheromones in sea cucumbers offers a new ecological perspective and may have practical applications for their aquaculture.
  40. Zazueta Novoa V, Onorato T, Reyes G, Oulhen N, Wessel G. Complexity of Yolk Proteins and Their Dynamics in the Sea Star Patiria miniata. Biol Bull. 2016;230:209-19 pubmed
    ..Among the echinoderms, members of the subphyla Echinozoa (sea urchins and sea cucumbers) express the major yolk protein (MYP) but not vitellogenin (Vtg), while an initial report has documented that ..
  41. Zhang J, Kitazawa D. Assessing the bio-mitigation effect of integrated multi-trophic aquaculture on marine environment by a numerical approach. Mar Pollut Bull. 2016;110:484-492 pubmed publisher
    ..of bottom dissolved oxygen concentration increased to 35% at maximum due to the ingestion of organic wastes by sea cucumbers. Numerical simulations indicate that seaweeds need to be harvested in a timely manner for maximal absorption ..
  42. Alqaisi K, Lamare M, Grattan D, Damsteegt E, Schneider W, Lokman P. A comparative study of vitellogenesis in Echinodermata: Lessons from the sea star. Comp Biochem Physiol A Mol Integr Physiol. 2016;198:72-86 pubmed publisher
    ..transferrin-like yolk component termed major yolk protein (MYP) is a major precursor protein in Echinoidea and Holothuroidea. In contrast, in Asteroidea a single vitellogenin (Vtg) was recently identified, but its role as primary yolk ..
  43. Li S, Li J, Zhi Z, Wei C, Wang W, Ding T, et al. Macromolecular properties and hypolipidemic effects of four sulfated polysaccharides from sea cucumbers. Carbohydr Polym. 2017;173:330-337 pubmed publisher
    ..Our results indicate that structural characteristics, including side branch and sulfation pattern can affect the chain conformation of polysaccharides, which determine their physicochemical properties and hypolipidemic activity. ..
  44. Wang Y, Chen G, Li K, Sun J, Song J, Zhan Y, et al. A novel MKK gene (AjMKK3/6) in the sea cucumber Apostichopus japonicus: Identification, characterization and its response to pathogenic challenge. Fish Shellfish Immunol. 2017;61:24-33 pubmed publisher
    ..splendidus infection, respectively. In general, the current study will enrich our knowledge of characterizations and immno-functions of MKK3/6 in sea cucumbers.
  45. Lv M, Chen H, Shao Y, Li C, Zhang W, Zhao X, et al. miR-92a regulates coelomocytes apoptosis in sea cucumber Apostichopus japonicus via targeting Aj14-3-3? in vivo. Fish Shellfish Immunol. 2017;69:211-217 pubmed publisher
    ..and Aj14-3-3? protein were detected in both LPS-exposed primary coelomocytes and Vibrio splendidus-challenged sea cucumbers. Over-expression of miR-92a by injection of miR-92a agomir significantly depressed the mRNA and protein ..
  46. Wargasetia T, Widodo -. Mechanisms of cancer cell killing by sea cucumber-derived compounds. Invest New Drugs. 2017;35:820-826 pubmed publisher
    ..Because of this, the use of natural substances with low toxicity is a good option. Sea cucumbers are one of many potential marine animals that contain valuable nutrients and medicinal properties...
  47. Barzkar N, Attaran Fariman G, Taheri A. Proximate composition and mineral contents in the body wall of two species of sea cucumber from Oman Sea. Environ Sci Pollut Res Int. 2017;: pubmed publisher
    ..Atomic absorption spectrophotometry of the ashes indicated the body wall of two species of sea cucumbers contained higher amounts of both macro minerals (92.5 mg/100 g Mg in S. horrens and 115 mg/100 g Mg in H...
  48. Li Y, Kikuchi M, Li X, Gao Q, Xiong Z, Ren Y, et al. Weighted gene co-expression network analysis reveals potential genes involved in early metamorphosis process in sea cucumber Apostichopus japonicus. Biochem Biophys Res Commun. 2018;495:1395-1402 pubmed publisher
    b>Sea cucumbers, one main class of Echinoderms, have a very fast and drastic metamorphosis process during their development. However, the molecular basis under this process remains largely unknown...
  49. Zhan Z, Li J, Xu K. Detection and Quantification of Two Parasitic Ciliates Boveria labialis and Boveria subcylindrica (Ciliophora: Scuticociliatia) by Fluorescence in situ Hybridization. J Eukaryot Microbiol. 2017;: pubmed publisher
    ..Boveria labialis and Boveria subcylindrica are obligate parasites that may cause high mortality in cultured sea cucumbers and bivalves...
  50. Zhang L, Feng Q, Sun L, Ding K, Huo D, Fang Y, et al. Differential gene expression in the intestine of sea cucumber (Apostichopus japonicus) under low and high salinity conditions. Comp Biochem Physiol Part D Genomics Proteomics. 2017;25:34-41 pubmed publisher
    ..The osmosis-specific DEGs identified in this study of A. japonicus will be important targets for further studies to understand the biochemical mechanisms involved with the adaption of sea cucumbers to changes in salinity.
  51. Mourão P, Vilanova E, Soares P. Unveiling the structure of sulfated fucose-rich polysaccharides via nuclear magnetic resonance spectroscopy. Curr Opin Struct Biol. 2017;50:33-41 pubmed publisher
    ..This constitutes an outstanding example of the potential of NMR in studying the chemical aspects of complex carbohydrates...
  52. Li C, Zhao Y, Liu T, Huang J, Zhang Q, Liu B, et al. The distribution and function characterization of the i type lysozyme from Apostichopus japonicus. Fish Shellfish Immunol. 2017;: pubmed publisher
    ..as an important innate immunity factor and plays a key defense role during host-pathogen interactions in sea cucumbers. From the radius of the antimicrobial zone, it was determined that the non-fusion Aj-iLys exerted a remarkable ..
  53. Suwansa Ard S, Chaiyamoon A, Talarovicova A, Tinikul R, Tinikul Y, Poomtong T, et al. Transcriptomic discovery and comparative analysis of neuropeptide precursors in sea cucumbers (Holothuroidea). Peptides. 2018;99:231-240 pubmed publisher
    ..In conclusion, we have obtained new insights into the neuropeptide signaling systems of holothurians, which will facilitate physiological studies that may enable advances in the aquaculture of sea cucumbers.
  54. Lv M, Chen H, Shao Y, Li C, Xu W, Zhang W, et al. miR-137 modulates coelomocyte apoptosis by targeting 14-3-3ζ in the sea cucumber Apostichopus japonicus. Dev Comp Immunol. 2017;67:86-96 pubmed publisher
    ..and Aj14-3-3ζ were detected in both LPS-exposed primary coelomocytes and Vibrio splendidus-challenged sea cucumbers, suggesting a positive regulatory interaction...
  55. Li K, Liu L, Shang S, Wang Y, Zhan Y, Song J, et al. cDNA cloning, expression and immune function analysis of a novel Rac1 gene (AjRac1) in the sea cucumber Apostichopus japonicus. Fish Shellfish Immunol. 2017;69:218-226 pubmed publisher
    ..With attempt to clarify characters and functions of Rac1 in sea cucumbers, full length cDNA of a Rac1 homolog in the sea cucumber Apostichopus japonicus (AjRac1) was cloned by ..
  56. Vasconcelos A, Pomin V. The Sea as a Rich Source of Structurally Unique Glycosaminoglycans and Mimetics. Microorganisms. 2017;5: pubmed publisher
    ..mimetics are the sulfated fucans and sulfated galactans found in brown, red and green algae, sea urchins and sea cucumbers. For adequate visualization, representations of all discussed molecules are given in both Haworth projections ..
  57. Zhang Y, Sun H, Qin S, Song Y, Si Y, Hou P, et al. Fucosylated Chondroitin Sulfate from Sea Cucumber Apostichopus japonicus Retards Atherosclerosis in Apolipoprotein E-deficient Mice. J Agric Food Chem. 2017;: pubmed publisher
    Fucosylated chondroitin sulfate (FucCS) is exclusively found at sea cucumbers, and it has been demonstrated to bear lipid-lowering effect in rodent models...
  58. Girich A, Isaeva M, Dolmatov I. Wnt and frizzled expression during regeneration of internal organs in the holothurian Eupentacta fraudatrix. Wound Repair Regen. 2017;: pubmed publisher
    ..Our data suggest that the Wnt signaling pathway plays a significant role in the regulation of regeneration of internal organs in holothurians.
  59. Huo D, Sun L, Li X, Ru X, Liu S, Zhang L, et al. Differential Expression of miRNAs in the Respiratory Tree of the Sea Cucumber Apostichopus japonicus Under Hypoxia Stress. G3 (Bethesda). 2017;7:3681-3692 pubmed publisher
    ..These results will provide a basis for future studies of miRNA regulation and molecular adaptive mechanisms in sea cucumbers under hypoxia stress.
  60. Vazzana M, Celi M, Chiaramonte M, Inguglia L, Russo D, Ferrantelli V, et al. Cytotoxic activity of Holothuria tubulosa (Echinodermata) coelomocytes. Fish Shellfish Immunol. 2017;72:334-341 pubmed publisher
    The immune system of marine invertebrates, in particular that of holothurians, still requires further study...
  61. Li X, Luo L, Cai Y, Yang W, Lin L, Li Z, et al. Structural Elucidation and Biological Activity of a Highly Regular Fucosylated Glycosaminoglycan from the Edible Sea Cucumber Stichopus herrmanni. J Agric Food Chem. 2017;65:9315-9323 pubmed publisher
    Edible sea cucumbers are widely used as a health food and medicine. A fucosylated glycosaminoglycan (FG) was purified from the high-value sea cucumber Stichopus herrmanni...
  62. Cavaleiro F, Rangel L, Frade D, Santos M. Syndesmis aethopharynx Westervelt & Kozloff, 1990 (Rhabdocoela: Umagillidae): a revisitation supported by scanning electron microscopy and molecular analyses. Syst Parasitol. 2017;94:1007-1017 pubmed publisher
    ..e. holothurians, and like them, may have evolved from some free-living or symbiotic Provorticidae ancestor. Syndesmis spp...
  63. Despalatović M, Cvitkovic I, Žuljević A. Checklist of the echinoderm fauna of the Adriatic Sea. Zootaxa. 2017;4353:101-116 pubmed publisher
    ..2 species from class Crinoidea, 23 species from class Asteroidea, 22 species from class Ophiuroidea, 22 species from class Echinoidea and 39 species from class Holothuroidea. Non-indigenous echinoderm species have not been observed.
  64. Woo S, Ogawa A, Tan S, Yasin Z, Kajihara H, Fujita T. A taxonomic revision of the genus <i>Apostichopus</i> (Holothuroidea: Stichopodidae) from Japan. Zootaxa. 2017;4350:121-135 pubmed publisher
    Complete redescriptions of sea cucumbers in the genus Apostichopus Liao, 1980 are provided using the type specimens and specimens deposited in the National Museum of Nature and Science, Tsukuba, Japan. The genus consists of A...
  65. Yamana Y, Tanaka H. A new species of <i>Chiridota</i> (Echinodermata: Holothuroidea: Apodida: Chiridotidae) from Japan, and First record of <i>C. rigida</i> from Japan. Zootaxa. 2017;4341:243-257 pubmed publisher
    ....
  66. Smirnov A, Panina E, Sanamyan N, Sanamyan K. <i>Scoliorhapis</i> <i>stepanovi</i>-new species of sea cucumber from the North-West Pacific (Holothuroidea: Synaptida: Chiridotidae: Taeniogyrinae) and some remarks on the genus <i>Scoliorhapis</i>. Zootaxa. 2017;4337:563-572 pubmed publisher
    ..Scoliorhapis stepanovi resembles S. lindbergi. A key for species of Scoliorhapis is provided...
  67. Zhang X, Sun L, Yuan J, Sun Y, Gao Y, Zhang L, et al. The sea cucumber genome provides insights into morphological evolution and visceral regeneration. PLoS Biol. 2017;15:e2003790 pubmed publisher
    Apart from sharing common ancestry with chordates, sea cucumbers exhibit a unique morphology and exceptional regenerative capacity. Here we present the complete genome sequence of an economically important sea cucumber, A...
  68. Mondol M, Shin H, Rahman M, Islam M. Sea Cucumber Glycosides: Chemical Structures, Producing Species and Important Biological Properties. Mar Drugs. 2017;15: pubmed publisher
    b>Sea cucumbers belonging to echinoderm are traditionally used as tonic food in China and other Asian countries. They produce abundant biologically active triterpene glycosides...
  69. Chen J, Ren Y, Wang G, Xia B, Li Y. Dietary supplementation of biofloc influences growth performance, physiological stress, antioxidant status and immune response of juvenile sea cucumber Apostichopus japonicus (Selenka). Fish Shellfish Immunol. 2017;72:143-152 pubmed publisher
    ..Juvenile sea cucumbers were fed five experimental diets containing graded levels of biofloc from 0% to 20% (referred as B0, B5, B10, ..
  70. He L, Zhang P, Huang J, Zhu F, Danchin A, Wang Y. The Enigmatic Genome of an Obligate Ancient Spiroplasma Symbiont in a Hadal Holothurian. Appl Environ Microbiol. 2018;84: pubmed publisher
    ..b>IMPORTANCE Sea cucumbers are major inhabitants in hadal trenches...
  71. Arast Y, Seyed Razi N, Nazemi M, Seydi E, Pourahmad J. Non Polar compounds of Persian Gulf Sea Cucumber Holothuria parva Selectively Induce Toxicity on Skin Mitochondria isolated from animal Model of Melanoma. Cutan Ocul Toxicol. 2017;:1-22 pubmed publisher
    ..Compounds obtained from sea cucumbers have shown to have anticancer activity through induction of apoptosis singling.
  72. Thandar A, Vinola L. The current status of Neocnus Arredondo, 1961 (Mammalia: Edentata: Pilosa: Megalonichidae) and a replacement name for its junior homonym in the sea cucumber family Cucumariidae (Echinodermata :Holothuroidea: Dendrochirotida: Cucumariidae). Zootaxa. 2017;4337:288-290 pubmed publisher
    ..A brief history of the senior homonym Neocnus (Edentata) is given followed by a short literature survey dealing with its junior homonym...