domestic silkworm

Summary

Alias: silk moth, silkworm, Bombyx mori, Bombyx mori Linnaeus, 1758

Top Publications

  1. Nada S, Chang P, Dignam J. Primary structure of the gene for glycyl-tRNA synthetase from Bombyx mori. J Biol Chem. 1993;268:7660-7 pubmed
    The primary structure of the gene encoding Bombyx mori glycyl-tRNA synthetase was determined by sequence analysis of one cDNA and two genomic clones...
  2. Koizumi N, Morozumi A, Imamura M, Tanaka E, Iwahana H, Sato R. Lipopolysaccharide-binding proteins and their involvement in the bacterial clearance from the hemolymph of the silkworm Bombyx mori. Eur J Biochem. 1997;248:217-24 pubmed
    ..R) mutant) were isolated and purified by affinity precipitation from the larval hemolymph of the silkworm Bombyx mori. These proteins were found to consist of two components with molecular masses of 43 kDa and 40 kDa by SDS/PAGE...
  3. Itoh M, Kanamori Y, Takao M, Eguchi M. Cloning of soluble alkaline phosphatase cDNA and molecular basis of the polymorphic nature in alkaline phosphatase isozymes of Bombyx mori midgut. Insect Biochem Mol Biol. 1999;29:121-9 pubmed
    A cDNA coding for soluble type alkaline phosphatase (sALP) of Bombyx mori was isolated. Deduced amino acid sequence showed high identities to various ALPs and partial similarities to ATPase of Manduca sexta...
  4. Kawaoka S, Katsuma S, Meng Y, Hayashi N, Mita K, Shimada T. Identification and characterization of globin genes from two lepidopteran insects, Bombyx mori and Samia cynthia ricini. Gene. 2009;431:33-8 pubmed publisher
    We describe the characterization of hemoglobin-like genes from two lepidopteran insects, Bombyx mori (Bmglobin) and Samia cynthia ricini (Scglobin)...
  5. Gu S, Lin J, Lin P. PTTH-stimulated ERK phosphorylation in prothoracic glands of the silkworm, Bombyx mori: role of Ca(2+)/calmodulin and receptor tyrosine kinase. J Insect Physiol. 2010;56:93-101 pubmed publisher
    ..hormone (PTTH) stimulated extracellular signal-regulated kinase (ERK) phosphorylation in prothoracic glands of Bombyx mori both in vitro and in vivo...
  6. Yu Q, Lu C, Li W, Xiang Z, Zhang Z. Annotation and expression of carboxylesterases in the silkworm, Bombyx mori. BMC Genomics. 2009;10:553 pubmed publisher
    ..Based on the newly assembled genome sequence, 76 putative COEs were identified in Bombyx mori. Relative to other Dipteran and Hymenopteran insects, alpha-esterases were significantly expanded in the ..
  7. Gu S, Yeh W, Young S, Lin P, Li S. TOR signaling is involved in PTTH-stimulated ecdysteroidogenesis by prothoracic glands in the silkworm, Bombyx mori. Insect Biochem Mol Biol. 2012;42:296-303 pubmed publisher
    ..that phosphoinositide 3-kinase (PI3K)/Akt signaling was involved in PTTH-stimulated ecdysteroidogenesis by Bombyx mori prothoracic glands. In the present study, downstream signaling of PI3K/Akt was further investigated...
  8. Adachi Yamada T, Iwami M, Kataoka H, Suzuki A, Ishizaki H. Structure and expression of the gene for the prothoracicotropic hormone of the silkmoth Bombyx mori. Eur J Biochem. 1994;220:633-43 pubmed
    We cloned and characterized two allelic variants of the gene for the Bombyx mori prothoracicotropic hormone (PTTH), a homodimeric 30-kDa brain secretory protein...
  9. Yoshida H, Kinoshita K, Ashida M. Purification of a peptidoglycan recognition protein from hemolymph of the silkworm, Bombyx mori. J Biol Chem. 1996;271:13854-60 pubmed
    A method was developed for obtaining a homogeneous silkworm hemolymph protein (peptidoglycan recognition protein, PGRP) which has affinity for peptidoglycan and the ability to trigger the prophenoloxidase cascade upon its binding to ..
  10. Kim M, Shin S, Bae K, Kim S, Park H. Molecular cloning of chitinase cDNAs from the silkworm, Bombyx mori and the fall webworm, Hyphantria cunea. Insect Biochem Mol Biol. 1998;28:163-71 pubmed
    cDNAs encoding chitinases were cloned and characterized from Bombyx mori and Hyphantria cunea, and their gene expression during the metamorphosis was also studied. The chitinase cDNA from B...

Detail Information

Publications117 found, 100 shown here

  1. Nada S, Chang P, Dignam J. Primary structure of the gene for glycyl-tRNA synthetase from Bombyx mori. J Biol Chem. 1993;268:7660-7 pubmed
    The primary structure of the gene encoding Bombyx mori glycyl-tRNA synthetase was determined by sequence analysis of one cDNA and two genomic clones...
  2. Koizumi N, Morozumi A, Imamura M, Tanaka E, Iwahana H, Sato R. Lipopolysaccharide-binding proteins and their involvement in the bacterial clearance from the hemolymph of the silkworm Bombyx mori. Eur J Biochem. 1997;248:217-24 pubmed
    ..R) mutant) were isolated and purified by affinity precipitation from the larval hemolymph of the silkworm Bombyx mori. These proteins were found to consist of two components with molecular masses of 43 kDa and 40 kDa by SDS/PAGE...
  3. Itoh M, Kanamori Y, Takao M, Eguchi M. Cloning of soluble alkaline phosphatase cDNA and molecular basis of the polymorphic nature in alkaline phosphatase isozymes of Bombyx mori midgut. Insect Biochem Mol Biol. 1999;29:121-9 pubmed
    A cDNA coding for soluble type alkaline phosphatase (sALP) of Bombyx mori was isolated. Deduced amino acid sequence showed high identities to various ALPs and partial similarities to ATPase of Manduca sexta...
  4. Kawaoka S, Katsuma S, Meng Y, Hayashi N, Mita K, Shimada T. Identification and characterization of globin genes from two lepidopteran insects, Bombyx mori and Samia cynthia ricini. Gene. 2009;431:33-8 pubmed publisher
    We describe the characterization of hemoglobin-like genes from two lepidopteran insects, Bombyx mori (Bmglobin) and Samia cynthia ricini (Scglobin)...
  5. Gu S, Lin J, Lin P. PTTH-stimulated ERK phosphorylation in prothoracic glands of the silkworm, Bombyx mori: role of Ca(2+)/calmodulin and receptor tyrosine kinase. J Insect Physiol. 2010;56:93-101 pubmed publisher
    ..hormone (PTTH) stimulated extracellular signal-regulated kinase (ERK) phosphorylation in prothoracic glands of Bombyx mori both in vitro and in vivo...
  6. Yu Q, Lu C, Li W, Xiang Z, Zhang Z. Annotation and expression of carboxylesterases in the silkworm, Bombyx mori. BMC Genomics. 2009;10:553 pubmed publisher
    ..Based on the newly assembled genome sequence, 76 putative COEs were identified in Bombyx mori. Relative to other Dipteran and Hymenopteran insects, alpha-esterases were significantly expanded in the ..
  7. Gu S, Yeh W, Young S, Lin P, Li S. TOR signaling is involved in PTTH-stimulated ecdysteroidogenesis by prothoracic glands in the silkworm, Bombyx mori. Insect Biochem Mol Biol. 2012;42:296-303 pubmed publisher
    ..that phosphoinositide 3-kinase (PI3K)/Akt signaling was involved in PTTH-stimulated ecdysteroidogenesis by Bombyx mori prothoracic glands. In the present study, downstream signaling of PI3K/Akt was further investigated...
  8. Adachi Yamada T, Iwami M, Kataoka H, Suzuki A, Ishizaki H. Structure and expression of the gene for the prothoracicotropic hormone of the silkmoth Bombyx mori. Eur J Biochem. 1994;220:633-43 pubmed
    We cloned and characterized two allelic variants of the gene for the Bombyx mori prothoracicotropic hormone (PTTH), a homodimeric 30-kDa brain secretory protein...
  9. Yoshida H, Kinoshita K, Ashida M. Purification of a peptidoglycan recognition protein from hemolymph of the silkworm, Bombyx mori. J Biol Chem. 1996;271:13854-60 pubmed
    A method was developed for obtaining a homogeneous silkworm hemolymph protein (peptidoglycan recognition protein, PGRP) which has affinity for peptidoglycan and the ability to trigger the prophenoloxidase cascade upon its binding to ..
  10. Kim M, Shin S, Bae K, Kim S, Park H. Molecular cloning of chitinase cDNAs from the silkworm, Bombyx mori and the fall webworm, Hyphantria cunea. Insect Biochem Mol Biol. 1998;28:163-71 pubmed
    cDNAs encoding chitinases were cloned and characterized from Bombyx mori and Hyphantria cunea, and their gene expression during the metamorphosis was also studied. The chitinase cDNA from B...
  11. Hirai M, Shinoda T, Kamimura M, Tomita S, Shiotsuki T. Bombyx mori orphan receptor, BmHR78: cDNA cloning, testis abundant expression and putative dimerization partner for Bombyx ultraspiracle. Mol Cell Endocrinol. 2002;189:201-11 pubmed
    We have identified a novel member of the nuclear receptor superfamily from the silkworm Bombyx mori, and named it as BmHR78, the B. mori hormone receptor...
  12. Ota A, Kusakabe T, Sugimoto Y, Takahashi M, Nakajima Y, Kawaguchi Y, et al. Cloning and characterization of testis-specific tektin in Bombyx mori. Comp Biochem Physiol B Biochem Mol Biol. 2002;133:371-82 pubmed
    A testis-specific cDNA library of Bombyx mori was constructed by an mRNA subtraction technique. Several clones were randomly selected and determined for their nucleotide sequences...
  13. Koike Y, Mita K, Suzuki M, Maeda S, Abe H, Osoegawa K, et al. Genomic sequence of a 320-kb segment of the Z chromosome of Bombyx mori containing a kettin ortholog. Mol Genet Genomics. 2003;269:137-49 pubmed publisher
    The sex chromosome constitution of the silkworm, Bombyx mori, is ZW in the female and ZZ in the male...
  14. Yamamoto K, Zhang P, Banno Y, Fujii H, Miake F, Kashige N, et al. Superoxide dismutase from the silkworm, Bombyx mori: sequence, distribution, and overexpression. Biosci Biotechnol Biochem. 2005;69:507-14 pubmed publisher
    ..This study focused on SOD from the silkworm, Bombyx mori (bmSOD). cDNA encoding bmSOD was amplified by reverse transcriptase-polymerase chain reaction...
  15. Selot R, Kumar V, Shukla S, Chandrakuntal K, Brahmaraju M, Dandin S, et al. Identification of a soluble NADPH oxidoreductase (BmNOX) with antiviral activities in the gut juice of Bombyx mori. Biosci Biotechnol Biochem. 2007;71:200-5 pubmed publisher
    ..We have characterized this protein as a soluble NADH-oxidoreductase-like protein (BmNOX). Treatment of live BmNPV particles with BmNOX inhibited the capability of the viral particles to infect BmN cells in vitro...
  16. Tsugehara T, Iwai S, Fujiwara Y, Mita K, Takeda M. Cloning and characterization of insect arylalkylamine N-acetyltransferase from Bombyx mori. Comp Biochem Physiol B Biochem Mol Biol. 2007;147:358-66 pubmed publisher
    Arylalkylamine N-acetyltransferase (AANAT) catalyzes N-acetylation of arylarkylamines. A cDNA of Bombyx mori insect AANAT (Bm-iAANAT) was found by searching an expressed-sequence tag (EST) database of B. mori (SilkBase)...
  17. Yun E, Lee J, Kwon O, Hwang J, Kim I, Kang S, et al. Bombyx mori transferrin: genomic structure, expression and antimicrobial activity of recombinant protein. Dev Comp Immunol. 2009;33:1064-9 pubmed publisher
    ..In this study, we identified and characterized Bombyx mori transferrin (BmTf)...
  18. Ito K, Katsuma S, Yamamoto K, Kadono Okuda K, Mita K, Shimada T. Yellow-e determines the color pattern of larval head and tail spots of the silkworm Bombyx mori. J Biol Chem. 2010;285:5624-9 pubmed publisher
    ..In two mutant strains, bts and its allele bts2, of the silkworm Bombyx mori, the larval head cuticle and anal plates are reddish brown instead of the white color found in the wild type...
  19. Seino A, Ogura T, Tsubota T, Shimomura M, Nakakura T, Tan A, et al. Characterization of juvenile hormone epoxide hydrolase and related genes in the larval development of the silkworm Bombyx mori. Biosci Biotechnol Biochem. 2010;74:1421-9 pubmed
    ..By searching a genome database of the silkworm, KAIKOBLAST, five JHEH-related genes (jheh-r), in addition to Bmjheh, were found...
  20. Tabunoki H, Ode H, Banno Y, Katsuma S, Shimada T, Mita K, et al. BmDJ-1 is a key regulator of oxidative modification in the development of the silkworm, Bombyx mori. PLoS ONE. 2011;6:e17683 pubmed publisher
    We cloned cDNA for the Bombyx mori DJ-1 protein (BmDJ-1) from the brains of larvae. BmDJ-1 is composed of 190 amino acids and encoded by 672 nucleotides...
  21. Bao Y, Xue J, Wu W, Wang Y, Lv Z, Zhang C. An immune-induced reeler protein is involved in the Bombyx mori melanization cascade. Insect Biochem Mol Biol. 2011;41:696-706 pubmed publisher
    In this study, we isolated two reeler cDNAs from bacteria-challenged larval fat bodies of the silkworm, Bombyx mori. A reeler domain spanned most of the coding regions of these two cDNAs, and their expression patterns were different in B...
  22. Kataoka H, Nagasawa H, Isogai A, Ishizaki H, Suzuki A. Prothoracicotropic hormone of the silkworm, Bombyx mori: amino acid sequence and dimeric structure. Agric Biol Chem. 1991;55:73-86 pubmed
    Prothoracicotropic hormone (PTTH) of the silkworm, Bombyx mori, was purified and its primary structure determined for the most part...
  23. Yasuhara Y, Koizumi Y, Katagiri C, Ashida M. Reexamination of properties of prophenoloxidase isolated from larval hemolymph of the silkworm Bombyx mori. Arch Biochem Biophys. 1995;320:14-23 pubmed publisher
    Prophenoloxidase in hemolymph of the silkworm (Bombyx mori) was purified by the method of Ashida (Ashida, M. (1971) Arch. Biochem. Biophys...
  24. Xu W, Sato Y, Ikeda M, Yamashita O. Molecular characterization of the gene encoding the precursor protein of diapause hormone and pheromone biosynthesis activating neuropeptide (DH-PBAN) of the silkworm, Bombyx mori and its distribution in some insects. Biochim Biophys Acta. 1995;1261:83-9 pubmed
    The diapause hormone is a 24 amino acid peptide amide which induces embryonic diapause of the silkworm, Bombyx mori. Diapause hormone, pheromone biosynthesis activating neuropeptide, and other three neuropeptides of FXPRL amide peptide ..
  25. Yaoi K, Nakanishi K, Kadotani T, Imamura M, Koizumi N, Iwahana H, et al. cDNA cloning and expression of Bacillus thuringiensis Cry1Aa toxin binding 120 kDa aminopeptidase N from Bombyx mori. Biochim Biophys Acta. 1999;1444:131-7 pubmed
    Bacillus thuringiensis Cry1Aa toxin binds to a 120 kDa putative receptor protein in the Bombyx mori midgut. Recently, this protein was purified and identified as glycosyl-phosphatidylinositol (GPI) anchored aminopeptidase N (APN)...
  26. Niu B, Meng Z, Tao Y, Lu S, Weng H, He L, et al. Cloning and alternative splicing analysis of Bombyx mori transformer-2 gene using silkworm EST database. Acta Biochim Biophys Sin (Shanghai). 2005;37:728-36 pubmed
    We have identified Bombyx mori transformer-2 gene (Bmtra-2) cDNA by blasting the EST database of B. mori. It was expressed in the whole life of the male and female silkworm and was observed as a band of 1.3 kb by Northern blot analysis...
  27. Shirai H, Kamimura M, Fujiwara H. Characterization of core promoter elements for ecdysone receptor isoforms of the silkworm, Bombyx mori. Insect Mol Biol. 2007;16:253-64 pubmed publisher
    ..We determined the transcription start sites of EcR-A and EcR-B1 isoforms of Bombyx mori and found that both core promoter regions consist of initiator (Inr) and downstream promoter elements (DPE) but ..
  28. Liu Y, Niu B, Weng H, Shen W, He L, Qi X, et al. [Cloning and structural analysis of MLP in the silkworm, Bombyx mori]. Yi Chuan. 2007;29:1097-102 pubmed
    ..Muscle LIM protein (MLP) gene in Bombyx mori has been cloned by blasting its EST database and PCR test in present report...
  29. Kawaoka S, Minami K, Katsuma S, Mita K, Shimada T. Developmentally synchronized expression of two Bombyx mori Piwi subfamily genes, SIWI and BmAGO3 in germ-line cells. Biochem Biophys Res Commun. 2008;367:755-60 pubmed publisher
    ..In this study, we examined the expression profiles of two Bombyx mori Piwi subfamily genes, silkworm Piwi (SIWI) and BmAGO3, which are possible partners of Bombyx piRNA-like small ..
  30. Wen H, Lan X, Cheng T, He N, Shiomi K, Kajiura Z, et al. Sequence structure and expression pattern of a novel anionic defensin-like gene from silkworm (Bombyx mori). Mol Biol Rep. 2009;36:711-6 pubmed publisher
    A defensin-like gene, BmdefA, was rediscovered in the silkworm genome and expressed sequence tags databases...
  31. Kaneko Y, Tanaka H, Ishibashi J, Iwasaki T, Yamakawa M. Gene expression of a novel defensin antimicrobial peptide in the silkworm, Bombyx mori. Biosci Biotechnol Biochem. 2008;72:2353-61 pubmed publisher
    cDNA encoding a novel defensin (BmDefensinB) was cloned from the fat body of the silkworm, Bombyx mori, and gene expression was analyzed. BmDefensinB showed typical structural characteristics of invertebrate defensins...
  32. Kaji K, Tomino S, Asano T. A serine protease in the midgut of the silkworm, Bombyx mori: protein sequencing, identification of cDNA, demonstration of its synthesis as zymogen form and activation during midgut remodeling. Insect Biochem Mol Biol. 2009;39:207-17 pubmed publisher
    We identified a serine protease with a molecular mass of 37kDa in the midgut of the silkworm, Bombyx mori. The activity of this protease (37-kDa protease: p37k) appears after pupation, when the metamorphic remodeling of the midgut is ..
  33. Wang H, Sakudoh T, Kawasaki H, Iwanaga M, Araki K, Fujimoto H, et al. Purification and expression analysis of imaginal disc growth factor in the silkworm, Bombyx mori. J Insect Physiol. 2009;55:1065-71 pubmed publisher
    ..we purified and sequenced a homolog of the Drosophila imaginal disc growth factor (IDGF) from the hemolymph of Bombyx mori (BmIDGF). Antibodies against BmIDGF were produced and subsequently used in immunoblotting analyses...
  34. Gu S, Young S, Lin J, Lin P. Involvement of PI3K/Akt signaling in PTTH-stimulated ecdysteroidogenesis by prothoracic glands of the silkworm, Bombyx mori. Insect Biochem Mol Biol. 2011;41:197-202 pubmed publisher
    ..and tyrosine kinase are involved in PTTH-stimulated ecdysteroidogenesis by the prothoracic glands of both Bombyx mori and Manduca sexta...
  35. Michel E, Damberger F, Ishida Y, Fiorito F, Lee D, Leal W, et al. Dynamic conformational equilibria in the physiological function of the Bombyx mori pheromone-binding protein. J Mol Biol. 2011;408:922-31 pubmed publisher
    The Bombyx mori pheromone-binding protein (BmorPBP) undergoes a pH-dependent conformational transition from a form at basic pH, which contains an open cavity suitable for ligand binding (BmorPBP(B)), to a form at pH 4...
  36. Lee W, Brey P. Isolation and characterization of the lysozyme-encoding gene from the silkworm Bombyx mori. Gene. 1995;161:199-203 pubmed
    We have isolated and characterized a Bombyx mori (Bm) cDNA encoding a lysozyme (Lyz)...
  37. Hara S, Yamakawa M. Moricin, a novel type of antibacterial peptide isolated from the silkworm, Bombyx mori. J Biol Chem. 1995;270:29923-7 pubmed
    ..shows antibacterial activity against Staphylococcus aureus was isolated from the hemolymph of the silkworm, Bombyx mori. The novel peptide consisted of 42 amino acids and was highly basic...
  38. Koizumi N, Imamura M, Kadotani T, Yaoi K, Iwahana H, Sato R. The lipopolysaccharide-binding protein participating in hemocyte nodule formation in the silkworm Bombyx mori is a novel member of the C-type lectin superfamily with two different tandem carbohydrate-recognition domains. FEBS Lett. 1999;443:139-43 pubmed
    ..characterized the lipopolysaccharide (LPS)-binding protein, BmLBP, from the larval hemolymph of the silkworm Bombyx mori. BmLBP is a pattern recognition molecule that recognizes the lipid A portion of LPS and participates in a ..
  39. Krieger J, Klink O, Mohl C, Raming K, Breer H. A candidate olfactory receptor subtype highly conserved across different insect orders. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2003;189:519-26 pubmed
    ..the identification of HR2 homologues in two further lepidopteran species, the moths Antheraea pernyi and Bombyx mori, which share 86-88% of their amino acids...
  40. Nakagawa T, Sakurai T, Nishioka T, Touhara K. Insect sex-pheromone signals mediated by specific combinations of olfactory receptors. Science. 2005;307:1638-42 pubmed
    We describe two male-specific olfactory receptors (ORs) in the silk moth, Bombyx mori, that are mutually exclusively expressed in a pair of adjacent pheromone-sensitive neurons of male antennae: One is specifically tuned to bombykol, the ..
  41. Ote M, Mita K, Kawasaki H, Daimon T, Kobayashi M, Shimada T. Identification of molting fluid carboxypeptidase A (MF-CPA) in Bombyx mori. Comp Biochem Physiol B Biochem Mol Biol. 2005;141:314-22 pubmed publisher
    ..we identified carboxypeptidase A (MF-CPA), which was induced during pupal ecdysis in the wing discs of Bombyx mori. Here, we report the functional characterization of MF-CPA...
  42. Fujiwara Y, Shindome C, Takeda M, Shiomi K. The roles of ERK and P38 MAPK signaling cascades on embryonic diapause initiation and termination of the silkworm, Bombyx mori. Insect Biochem Mol Biol. 2006;36:47-53 pubmed
    ..Phospho-ERK levels were maintained with diapause-interrupting treatment and declined with diapause-sustaining treatment. ERK phosphorylation is considered to have a role in diapause termination and in the resumption of development...
  43. Yamamoto T, Sawada H. In-vitro phosphorylation activity by recombinant alpha and beta subunits of Bombyx mori casein kinase 2. Zoolog Sci. 2008;25:799-805 pubmed publisher
    ..of the catalytic activity of casein kinase 2 (CK2) during early embryonic development in the silkworm, Bombyx mori, we attempted an in-vitro functional analysis by using the recombinant alpha and beta subunits of B...
  44. Okamoto N, Yamanaka N, Satake H, Saegusa H, Kataoka H, Mizoguchi A. An ecdysteroid-inducible insulin-like growth factor-like peptide regulates adult development of the silkmoth Bombyx mori. FEBS J. 2009;276:1221-32 pubmed publisher
    ..Here we show that a novel insulin family peptide of the silkmoth Bombyx mori, which was purified and sequenced from the hemolymph, is more like IGFs than like insulin, in contrast to ..
  45. Hu C, Zhang X, Teng Y, Hu H, Li W. Structure of autophagy-related protein Atg8 from the silkworm Bombyx mori. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010;66:787-90 pubmed publisher
    ..In the 2.40 A crystal structure of Atg8 from the silkworm Bombyx mori reported here, the ubiquitin fold at the C-terminus is preceded by two additional helices at the N-terminus.
  46. He X, Tzotzos G, Woodcock C, Pickett J, Hooper T, Field L, et al. Binding of the general odorant binding protein of Bombyx mori BmorGOBP2 to the moth sex pheromone components. J Chem Ecol. 2010;36:1293-305 pubmed publisher
    ..In the silkworm, Bombyx mori (L...
  47. Kiuchi T, Banno Y, Katsuma S, Shimada T. Mutations in an amino acid transporter gene are responsible for sex-linked translucent larval skin of the silkworm, Bombyx mori. Insect Biochem Mol Biol. 2011;41:680-7 pubmed publisher
    The sex-linked translucent (os) mutation in the silkworm, Bombyx mori, confers slightly translucent larval skin resulting from a decrease in the incorporation of uric acid into epidermal cells...
  48. Wang Q, Chen L, Chen L, Shen B, Liu Y, Chen J, et al. The tau-like protein in silkworm (Bombyx mori) induces microtubule bundle formation. Front Biosci (Elite Ed). 2012;4:998-1008 pubmed
    ..Here, we cloned and identified a tau-like protein BmTau from silkworm, Bombyx mori (GenBank accession number FJ904935)...
  49. Casati B, Terova G, Cattaneo A, Rimoldi S, Franzetti E, de Eguileor M, et al. Molecular cloning, characterization and expression analysis of ATG1 in the silkworm, Bombyx mori. Gene. 2012;511:326-37 pubmed publisher
    ..A complete coding sequence of ATG1 is not available for the silkworm, Bombyx mori which is a good model for studying the autophagic process...
  50. Mori S, Izumi S, Tomino S. Structures and organization of major plasma protein genes of the silkworm Bombyx mori. J Mol Biol. 1991;218:7-12 pubmed
    In the silkworm, Bombyx mori, a group of structurally related proteins, termed 30K proteins, accumulate in the hemolymph of the last instar larvae...
  51. Su Z, Ikeda M, Sato Y, Saito H, Imai K, Isobe M, et al. Molecular characterization of ovary trehalase of the silkworm, Bombyx mori and its transcriptional activation by diapause hormone. Biochim Biophys Acta. 1994;1218:366-74 pubmed
    We have isolated a cDNA encoding ovary trehalase of the silkworm, Bombyx mori. Sequence analyses revealed that the isolated cDNA contains 3143 nucleotides and comprises 579 amino acids, including a cleavable signal sequence and five ..
  52. Yano K, Sakurai M, Watabe S, Izumi S, Tomino S. Structure and expression of mRNA for vitellogenin in Bombyx mori. Biochim Biophys Acta. 1994;1218:1-10 pubmed
    Vitellogenin, a precursor of major yolk protein of the silkworm, Bombyx mori is a tetramer composed of each two molecules of heavy and light subunits. We cloned mRNA sequence for the B. mori vitellogenin and analyzed its structure...
  53. Hu Z, Chen K, Wang L, Yao Q. Identification and characterization of Bombyx mori eIF5A gene through bioinformatics approaches. In Silico Biol. 2005;5:573-80 pubmed
    ..This gene has been registered in GenBank under the accession number DQ104412...
  54. Hong S, Kusakabe T, Lee J, Tatsuke T, Kawaguchi Y, Kang M, et al. Structure and expression analysis of the cecropin-E gene from the silkworm, Bombyx mori. Biosci Biotechnol Biochem. 2008;72:1992-8 pubmed publisher
    ..By silkworm cDNA microarray analysis, a novel type of Cecropin family gene was identified as a cDNA up-regulated in early ..
  55. Fujii T, Daimon T, Uchino K, Banno Y, Katsuma S, Sezutsu H, et al. Transgenic analysis of the BmBLOS2 gene that governs the translucency of the larval integument of the silkworm, Bombyx mori. Insect Mol Biol. 2010;19:659-67 pubmed publisher
    The larval integument of the silkworm, Bombyx mori, is opaque because urate granules accumulate in the epidermis...
  56. Gao K, Deng X, Qian H, Wu P, Qin G, Liu T, et al. Novel protein of IBP from silkworm, Bombyx mori, involved in cytoplasmic polyhedrosis virus infection. J Invertebr Pathol. 2012;110:83-91 pubmed publisher
    ..cDNA of a novel insulin-related peptide-binding protein (named BmIBP2) was identified from silkworm, Bombyx mori, using rapid amplification of cDNA ends...
  57. Shi G, Yu Q, Shi L, Zhang Z. Molecular cloning and characterization of peroxiredoxin 4 involved in protection against oxidative stress in the silkworm Bombyx mori. Insect Mol Biol. 2012;21:581-92 pubmed publisher
    ..Here, we describe the cloning and characterization of a Prx4 cDNA of the silkworm Bombyx mori (BmPrx4)...
  58. Abraham E, Sezutsu H, Kanda T, Sugasaki T, Shimada T, Tamura T. Identification and characterisation of a silkworm ABC transporter gene homologous to Drosophila white. Mol Gen Genet. 2000;264:11-9 pubmed
    In the silkworm, Bombyx mori, many eye- and egg-colour mutations affecting the synthesis and accumulation of ommochrome pigments have been described...
  59. Maeda T, Lee J, Miyagawa Y, Koga K, Kawaguchi Y, Kusakabe T. Cloning and characterization of a ribonuclease L inhibitor from the silkworm, Bombyx mori. DNA Seq. 2005;16:21-7 pubmed
    ..In the present study, we cloned a cDNA of a silkworm RLI homolog, termed BmRLI, and its nucleotide sequence was determined...
  60. Osanai M, Kojima K, Futahashi R, Yaguchi S, Fujiwara H. Identification and characterization of the telomerase reverse transcriptase of Bombyx mori (silkworm) and Tribolium castaneum (flour beetle). Gene. 2006;376:281-9 pubmed publisher
    ..In contrast, the domestic silkworm Bombyx mori contains TTAGG-type telomeric repeats, but the telomerase activity has not been detected in all ..
  61. Galindo M, Pueyo J, Fouix S, Bishop S, Couso J. Peptides encoded by short ORFs control development and define a new eukaryotic gene family. PLoS Biol. 2007;5:e106 pubmed publisher
    ..Our results open a new avenue for the annotation and functional analysis of genes and sequenced genomes, in which thousands of short ORFs are still uncharacterised...
  62. Jin Y, Tian N, Cao J, Liang J, Yang Z, Lv J. RNA editing and alternative splicing of the insect nAChR subunit alpha6 transcript: evolutionary conservation, divergence and regulation. BMC Evol Biol. 2007;7:98 pubmed publisher
    ..from different insects spanning ~300 million years of evolution- Drosophila melanogaster, Anopheles gambiae, Bombyx mori, Tribolium castaneum and Apis mellifera...
  63. Kômoto N, Quan G, Sezutsu H, Tamura T. A single-base deletion in an ABC transporter gene causes white eyes, white eggs, and translucent larval skin in the silkworm w-3(oe) mutant. Insect Biochem Mol Biol. 2009;39:152-6 pubmed publisher
    The w-3(oe) silkworm mutant has white eyes and eggs due to the absence of ommochrome pigments in the eye pigment cells and serosa cells...
  64. Tatematsu K, Yamamoto K, Uchino K, Narukawa J, Iizuka T, Banno Y, et al. Positional cloning of silkworm white egg 2 (w-2) locus shows functional conservation and diversification of ABC transporters for pigmentation in insects. Genes Cells. 2011;16:331-42 pubmed publisher
    ..The white egg 2 (w-2) mutant of the silkworm, Bombyx mori, has white eggs and eyes because of lack of ommochrome granules in the serosa and eyes...
  65. Atsumi S, Miyamoto K, Yamamoto K, Narukawa J, Kawai S, Sezutsu H, et al. Single amino acid mutation in an ATP-binding cassette transporter gene causes resistance to Bt toxin Cry1Ab in the silkworm, Bombyx mori. Proc Natl Acad Sci U S A. 2012;109:E1591-8 pubmed publisher
    ..By using Bombyx mori as a model, we identified a candidate gene for a recessive form of resistance to Cry1Ab toxin on chromosome 15 ..
  66. Kayukawa T, Minakuchi C, Namiki T, Togawa T, Yoshiyama M, Kamimura M, et al. Transcriptional regulation of juvenile hormone-mediated induction of Krüppel homolog 1, a repressor of insect metamorphosis. Proc Natl Acad Sci U S A. 2012;109:11729-34 pubmed publisher
    ..of Kr-h1 induction, we first cloned cDNAs encoding Kr-h1 (BmKr-h1) and Met (BmMet1 and BmMet2) homologs from Bombyx mori. In a B. mori cell line, BmKr-h1 was rapidly induced by subnanomolar levels of natural JHs...
  67. Mita K, Morimyo M, Okano K, Koike Y, Nohata J, Kawasaki H, et al. The construction of an EST database for Bombyx mori and its application. Proc Natl Acad Sci U S A. 2003;100:14121-6 pubmed
    To build a foundation for the complete genome analysis of Bombyx mori, we have constructed an EST database...
  68. Krauss V, Pecyna M, Kurz K, Sass H. Phylogenetic mapping of intron positions: a case study of translation initiation factor eIF2gamma. Mol Biol Evol. 2005;22:74-84 pubmed
    ..We also performed tree reconstructions using the eIF2gamma protein sequences and intron positioning as phylogenetic information. Our results support the monophyly of Viridoplantae, Ascomycota, Homobasidiomyceta, and Apicomplexa. ..
  69. Mounier N, Prudhomme J. Isolation of actin genes in Bombyx mori: the coding sequence of a cytoplasmic actin gene expressed in the silk gland is interrupted by a single intron in an unusual position. Biochimie. 1986;68:1053-61 pubmed
    ..gene(s) coding for the actin present in the microfilaments involved in the secretion of silk, we have probed a Bombyx mori genomic library with a Drosophila actin cDNA clone and selected 16 recombinant phages...
  70. Quan G, Kim I, Komoto N, Sezutsu H, Ote M, Shimada T, et al. Characterization of the kynurenine 3-monooxygenase gene corresponding to the white egg 1 mutant in the silkworm Bombyx mori. Mol Genet Genomics. 2002;267:1-9 pubmed
    ..A silkworm mutant, white egg 1 ( w-1), has been shown to be deficient in this enzyme activity...
  71. Tabunoki H, Sugiyama H, Tanaka Y, Fujii H, Banno Y, Jouni Z, et al. Isolation, characterization, and cDNA sequence of a carotenoid binding protein from the silk gland of Bombyx mori larvae. J Biol Chem. 2002;277:32133-40 pubmed
    A carotenoid binding protein (CBP) has been isolated from the silk glands of Bombyx mori larvae. The protein has an apparent molecular mass of 33 kDa and binds carotenoids in a 1:1 molar ratio...
  72. Niwa R, Matsuda T, Yoshiyama T, Namiki T, Mita K, Fujimoto Y, et al. CYP306A1, a cytochrome P450 enzyme, is essential for ecdysteroid biosynthesis in the prothoracic glands of Bombyx and Drosophila. J Biol Chem. 2004;279:35942-9 pubmed
    ..P450 gene, designated Cyp306a1, that is essential for ecdysteroid biosynthesis in the PGs of the silkworm Bombyx mori and fruit fly Drosophila melanogaster...
  73. Lee J, Kusakabe T, Kawaguchi Y, Miyagawa Y, Takahashi M, Mon H, et al. Molecular cloning and characterization of the translationally controlled tumor protein gene in Bombyx mori. Comp Biochem Physiol B Biochem Mol Biol. 2004;139:35-43 pubmed
    ..To elucidate its molecular basis of the expression and physiological significance, a cDNA encoding for the Bombyx mori Tctp (BmTctp) was deduced by editing the partial cDNA sequences registered in a Bombyx EST database...
  74. Namiki T, Niwa R, Sakudoh T, Shirai K, Takeuchi H, Kataoka H. Cytochrome P450 CYP307A1/Spook: a regulator for ecdysone synthesis in insects. Biochem Biophys Res Commun. 2005;337:367-74 pubmed
    ..To identify genes functioning in the PG of the silkworm, Bombyx mori, we used differential display PCR and focused on a cytochrome P450 gene designated Cyp307a1...
  75. Sakudoh T, Sezutsu H, Nakashima T, Kobayashi I, Fujimoto H, Uchino K, et al. Carotenoid silk coloration is controlled by a carotenoid-binding protein, a product of the Yellow blood gene. Proc Natl Acad Sci U S A. 2007;104:8941-6 pubmed publisher
    ..The Y (Yellow blood) gene, a critical cocoon color determinant in the silkworm Bombyx mori, controls the uptake of carotenoids into the intestinal mucosa and the silk gland...
  76. Tomoyasu Y, Miller S, Tomita S, Schoppmeier M, Grossmann D, Bucher G. Exploring systemic RNA interference in insects: a genome-wide survey for RNAi genes in Tribolium. Genome Biol. 2008;9:R10 pubmed publisher
    ..Thus, insects may use an alternative mechanism for the systemic RNAi response. Understanding this process would assist with rendering other insects amenable to systemic RNAi, and may influence pest control approaches. ..
  77. Ohnishi A, Hashimoto K, Imai K, Matsumoto S. Functional characterization of the Bombyx mori fatty acid transport protein (BmFATP) within the silkmoth pheromone gland. J Biol Chem. 2009;284:5128-36 pubmed publisher
    ..By exploiting this unique system in the PG of the silkmoth, Bombyx mori, we found that BmFATP is predominantly expressed in the PG and undergoes up-regulation 1 day prior to eclosion...
  78. Ogura T, Tan A, Tsubota T, Nakakura T, Shiotsuki T. Identification and expression analysis of ras gene in silkworm, Bombyx mori. PLoS ONE. 2009;4:e8030 pubmed publisher
    ..We identified three ras cDNAs from the silk worm, Bombyx mori. These sequences corresponded to three Ras of Drosophila melanogaster, but not to three mammalian Ras (H-Ras, K-..
  79. Zhan S, Guo Q, Li M, Li M, Li J, Miao X, et al. Disruption of an N-acetyltransferase gene in the silkworm reveals a novel role in pigmentation. Development. 2010;137:4083-90 pubmed publisher
    ..The melanism (mln) mutant of the silkworm Bombyx mori is notable for its strong black coloration, phenotypic differences between larval and adult stages, and its ..
  80. Cao G, Zhang Y, Xue R, Zhu Y, Wei Y, Zheng X, et al. Alternative splicing, expression patterns and promoter characters of vasa-like gene from the silkworm, Bombyx mori. Mol Biol Rep. 2012;39:5967-76 pubmed publisher
    VASA is considered to be one of the most reliable molecular marker of germ cells. In order to study the Bombyx mori vasa-like gene (Bmvlg), the cDNAs of Bmvlg were cloned and sequenced, and the results showed that ..
  81. Duan J, Xu H, Wang F, Ma S, Zha X, Guo H, et al. Novel female-specific trans-spliced and alternative splice forms of dsx in the silkworm Bombyx mori. Biochem Biophys Res Commun. 2013;431:630-5 pubmed publisher
    The Bombyx mori doublesex gene (Bmdsx) plays an important role in somatic sexual development. Its pre-mRNA splices in a sex-specific manner to generate two female-specific and one male-specific splice forms...
  82. Michaille J, Garel A, Prudhomme J. Cloning and characterization of the highly polymorphic Ser2 gene of Bombyx mori. Gene. 1990;86:177-84 pubmed
    Three alleles of the sericin (Ser) 2-encoding gene (Ser2), called L, C and mC, were isolated from a Bombyx mori genomic library, and two related ones, called mCL and Cv, were also characterized in B. mori European strains...
  83. Yoshiga T, Okano K, Mita K, Shimada T, Matsumoto S. cDNA cloning of acyl-CoA desaturase homologs in the silkworm, Bombyx mori. Gene. 2000;246:339-45 pubmed
    ..desaturase clones from a pheromone gland cDNA library by using the EST (expressed sequence tag) database of Bombyx mori. The putative acyl-CoA desaturases encoded by the clones desat 1 (2029bp) and desat 2 (2341bp) have 98% ..
  84. Niwa R, Sakudoh T, Namiki T, Saida K, Fujimoto Y, Kataoka H. The ecdysteroidogenic P450 Cyp302a1/disembodied from the silkworm, Bombyx mori, is transcriptionally regulated by prothoracicotropic hormone. Insect Mol Biol. 2005;14:563-71 pubmed
    ..Here we report on Cyp302a1/disembodied (dib-Bm), one of the Halloween P450s in the silkworm Bombyx mori that is a carbon-22 hydroxylase...
  85. Zhong Y, Mita K, Shimada T, Kawasaki H. Glycine-rich protein genes, which encode a major component of the cuticle, have different developmental profiles from other cuticle protein genes in Bombyx mori. Insect Biochem Mol Biol. 2006;36:99-110 pubmed
    Three types of GRP (glycine-rich proteins) cDNAs were identified in the EST database of Bombyx mori. These came from 21 ESTs in the W3-stage wing disc EST library. We named them BmGRP1, BmGRP2 and BmGRP3...
  86. Zhou Q, Li Y, Shen X, Yi Y, Zhang Y, Zhang Z. The scaleless wings mutant in Bombyx mori is associated with a lack of scale precursor cell differentiation followed by excessive apoptosis. Dev Genes Evol. 2006;216:721-6 pubmed
    The scaleless wings mutant in Bombyx mori (scaleless, sl) was previously reported morphologically. In the present study, we give data to clarify the mechanism of the mutation at the developmental level...
  87. Cao J, Tong C, Wu X, Lv J, Yang Z, Jin Y. Identification of conserved microRNAs in Bombyx mori (silkworm) and regulation of fibroin L chain production by microRNAs in heterologous system. Insect Biochem Mol Biol. 2008;38:1066-71 pubmed publisher
    ..Little study has been performed on identifying miRNAs in Bombyx mori (silkworm)...
  88. Takahasi K, Ochiai M, Horiuchi M, Kumeta H, Ogura K, Ashida M, et al. Solution structure of the silkworm betaGRP/GNBP3 N-terminal domain reveals the mechanism for beta-1,3-glucan-specific recognition. Proc Natl Acad Sci U S A. 2009;106:11679-84 pubmed publisher
    ..This report shows the solution structure of the N-terminal beta-1,3-glucan recognition domain of silkworm betaGRP...
  89. Moriya K, Tsubota T, Ishibashi N, Yafune A, Suzuki T, Kobayashi J, et al. Bombyx mori Ras proteins BmRas1, BmRas2 and BmRas3 are neither farnesylated nor palmitoylated but are geranylgeranylated. Insect Mol Biol. 2010;19:291-301 pubmed publisher
    The lipid modifications which occur on Bombyx mori Ras proteins BmRas1, BmRas2 and BmRas3 were studied by metabolic labelling in an insect cell-free protein synthesis system and in a baculovirus expression system, using specific ..
  90. Tsubota T, Shimomura M, Ogura T, Seino A, Nakakura T, Mita K, et al. Molecular characterization and functional analysis of novel carboxyl/cholinesterases with GQSAG motif in the silkworm Bombyx mori. Insect Biochem Mol Biol. 2010;40:100-12 pubmed publisher
    ..a juvenile hormone (JH)-selective esterase (JHE) that is important for JH titer regulation in the silkworm Bombyx mori. Here, we sought to determine whether multiple genes might function as JH-specific esterase in this species...
  91. Zhou S, Zhou Q, Liu Y, Wang S, Wen D, He Q, et al. Two Tor genes in the silkworm Bombyx mori. Insect Mol Biol. 2010;19:727-35 pubmed publisher
    ..Tor genes, BmTor1 and BmTor2, were identified as a pair of inverted repeats in the genome of the silkworm Bombyx mori. The synteny of BmTor1 and CG8360 indicates that BmTor1 is the orthologue while BmTor2 is a duplicate...
  92. Hull J, Lee J, Matsumoto S. Identification of specific sites in the third intracellular loop and carboxyl terminus of the Bombyx mori pheromone biosynthesis activating neuropeptide receptor crucial for ligand-induced internalization. Insect Mol Biol. 2011;20:801-11 pubmed publisher
    ..Using fluorescent Bombyx mori PBANR (BmPBANR) chimeras to study PBANR regulation, we previously showed that BmPBANR undergoes rapid ligand-..
  93. Sugahara R, Mon H, Lee J, Kusakabe T. Monoubiquitination-dependent chromatin loading of FancD2 in silkworms, a species lacking the FA core complex. Gene. 2012;501:180-7 pubmed publisher
    ..Silkworm, Bombyx mori, lacks apparent homologues of the FA core complex...
  94. Zhang P, Cao G, Sheng J, Xue R, Gong C. BmTGIF, a Bombyx mori homolog of Drosophila DmTGIF, regulates progression of spermatogenesis. PLoS ONE. 2012;7:e47861 pubmed publisher
    ..In this study, we investigated the characteristics and functions of BmTGIF, a Bombyx mori homolog of DmTGIF. Like DmTGIF, BmTGIF is predominantly expressed in the testes and ovaries...
  95. Sakudoh T, Kuwazaki S, Iizuka T, Narukawa J, Yamamoto K, Uchino K, et al. CD36 homolog divergence is responsible for the selectivity of carotenoid species migration to the silk gland of the silkworm Bombyx mori. J Lipid Res. 2013;54:482-95 pubmed publisher
    ..The products of the Yellow cocoon (C) gene and the Flesh (F) gene of the silkworm Bombyx mori determine the selectivity for transport of lutein and β-carotene, respectively, to the silk gland...
  96. Ma L, Liu S, Shi M, Chen X, Li S. Ras1CA-upregulated BCPI inhibits cathepsin activity to prevent tissue destruction of the Bombyx posterior silk gland. J Proteome Res. 2013;12:1924-34 pubmed publisher
    Using the GAL4/UAS transgenic system established in the silkworm, Bombyx mori, we have previously reported that overexpression of the Ras1(CA) oncogene specifically in the posterior silk gland (PSG) resulted in improved fibroin synthesis,..
  97. Narumi H, Hishida T, Sasaki T, Feng D, Doolittle R. Molecular cloning of silkworm (Bombyx mori) antichymotrypsin. A new member of the serpin superfamily of proteins from insects. Eur J Biochem. 1993;214:181-7 pubmed
    The cDNA of silkworm (Bombyx mori) antichymotrypsin (sw-Achy) was cloned from larval fat body and its nucleotide sequence was determined...
  98. Matsuoka T, Fujiwara H. Expression of ecdysteroid-regulated genes is reduced specifically in the wing discs of the wing-deficient mutant (fl) of Bombyx mori. Dev Genes Evol. 2000;210:120-8 pubmed
    The wing-deficient mutant, flügellos (fl), of the silkworm, lacks four wings in the pupa and the adult. Previous studies have suggested that the fl wing discs lose responsiveness to ecdysteroid during metamorphosis...
  99. Hirai M, Kamimura M, Kikuchi K, Yasukochi Y, Kiuchi M, Shinoda T, et al. cDNA cloning and characterization of Bombyx mori juvenile hormone esterase: an inducible gene by the imidazole insect growth regulator KK-42. Insect Biochem Mol Biol. 2002;32:627-35 pubmed
    ..IGR) imidazole KK-42 induces hemolymph juvenile hormone esterase activity and precocious metamorphosis in Bombyx mori. As an initial step to understand the molecular action of KK-42, we isolated a full-length of juvenile hormone ..
  100. Ijiro T, Urakawa H, Yasukochi Y, Takeda M, Fujiwara Y. cDNA cloning, gene structure, and expression of Broad-Complex (BR-C) genes in the silkworm, Bombyx mori. Insect Biochem Mol Biol. 2004;34:963-9 pubmed
    To clarify the molecular mechanisms of metamorphosis, we analyzed the Broad-Complex (BR-C) gene in the silkworm, Bombyx mori. We cloned cDNAs for the full coding regions of the Z1, Z2, and Z4 isoforms of BR-C...
  101. Hull J, Ohnishi A, Moto K, Kawasaki Y, Kurata R, Suzuki M, et al. Cloning and characterization of the pheromone biosynthesis activating neuropeptide receptor from the silkmoth, Bombyx mori. Significance of the carboxyl terminus in receptor internalization. J Biol Chem. 2004;279:51500-7 pubmed
    ..a full-length 2780-nucleotide clone encoding a 46-kDa G protein-coupled receptor was amplified from a Bombyx mori pheromone gland cDNA library...