Hydra vulgaris

Summary

Alias: Hydra attenuata, Hydra vulgaris Pallas, 1766

Top Publications

  1. ncbi Evolutionary conservation of a cell fate specification gene: the Hydra achaete-scute homolog has proneural activity in Drosophila
    A Grens
    Developmental Biology Center, University of California, Irvine 92717, USA
    Development 121:4027-35. 1995
  2. ncbi CnNK-2, an NK-2 homeobox gene, has a role in patterning the basal end of the axis in hydra
    A Grens
    Developmental Biology Center, University of California, Irvine, California, 92717, USA
    Dev Biol 180:473-88. 1996
  3. ncbi Budhead, a fork head/HNF-3 homologue, is expressed during axis formation and head specification in hydra
    D E Martinez
    Developmental Biology Center, University of California, Irvine 92697, USA
    Dev Biol 192:523-36. 1997
  4. ncbi Spinalin, a new glycine- and histidine-rich protein in spines of Hydra nematocysts
    A W Koch
    Department of Biophysical Chemistry, Biozentrum, University of Basel, Klingelbergstrasse 70, Switzerland
    J Cell Sci 111:1545-54. 1998
  5. ncbi Identification of caspases and apoptosis in the simple metazoan Hydra
    M Cikala
    Zoologisches Institut, Universitat Munchen, Luisenstrasse 14, Munchen, 80333, Germany
    Curr Biol 9:959-62. 1999
  6. ncbi HyAlx, an aristaless-related gene, is involved in tentacle formation in hydra
    K M Smith
    Developmental Biology Center, and Department of Developmental and Cell Biology, University of California, Irvine, CA 92697, USA
    Development 127:4743-52. 2000
  7. pmc Trans-spliced leader addition to mRNAs in a cnidarian
    N A Stover
    Department of Biological Chemistry and the Developmental Biology Center, University of California, Irvine, CA 92697 1700, USA
    Proc Natl Acad Sci U S A 98:5693-8. 2001
  8. ncbi Isolation of a putative peroxidase, a target for factors controlling foot-formation in the coelenterate hydra
    Sabine A H Hoffmeister-Ullerich
    Zentrum für Molekulare Neurobiologie, University of Hamburg, Germany
    Eur J Biochem 269:4597-606. 2002
  9. ncbi Nowa, a novel protein with minicollagen Cys-rich domains, is involved in nematocyst formation in Hydra
    Ulrike Engel
    Institute of Zoology, Darmstadt University of Technology, 64287 Darmstadt, Germany
    J Cell Sci 115:3923-34. 2002
  10. ncbi Cloning and characterisation of PKB and PRK homologs from Hydra and the evolution of the protein kinase family
    Michaela Herold
    Ludwig Maximilians University Munich, Zoological Institute, Luisenstrasse 14, 80333 Munich, Germany
    Dev Genes Evol 212:513-9. 2002

Research Grants

  1. Daniel E Martinez; Fiscal Year: 2014
  2. MODEL FOR EPITHELIAL/BASEMENT MEMBRANE INTERACTIONS
    MICHAEL SARRAS; Fiscal Year: 1992
  3. A MODEL FOR BASEMENT MEMBRANE THICKENING IN DIABETES
    MICHAEL SARRAS; Fiscal Year: 1991

Patents

  1. Benzo[a]pyrene responsive genes in Hydra magnipapillata and the method for diagnosing aquatic environment pollution using the same
  2. Perfluorooctane sulfonate responsive genes in Hydra magnipapillata and the method for diagnosing aquatic environment pollution using the same
  3. Biological effect monitoring by means of transgenic hydra
  4. Peptide antibiotic made of hydra and coding gene
  5. Process for the production of lutein
  6. Plants with increased yield (nue)
  7. No title supplied
  8. Process for the control of production of fine chemicals
  9. Proteins associated with abiotic stress response and homologs
  10. Mutant Endoglycoceramidases With Enhanced Synthetic Activity

Scientific Experts

Detail Information

Publications139 found, 100 shown here

  1. ncbi Evolutionary conservation of a cell fate specification gene: the Hydra achaete-scute homolog has proneural activity in Drosophila
    A Grens
    Developmental Biology Center, University of California, Irvine 92717, USA
    Development 121:4027-35. 1995
    ..We have isolated and characterized a cnidarian achaete-scute homolog, CnASH, from Hydra vulgaris, a representative of an evolutionarily ancient branch of metazoans...
  2. ncbi CnNK-2, an NK-2 homeobox gene, has a role in patterning the basal end of the axis in hydra
    A Grens
    Developmental Biology Center, University of California, Irvine, California, 92717, USA
    Dev Biol 180:473-88. 1996
    ..Here we describe the characterization of the NK-2 homolog CnNK-2 from Hydra vulgaris, a freshwater cnidarian...
  3. ncbi Budhead, a fork head/HNF-3 homologue, is expressed during axis formation and head specification in hydra
    D E Martinez
    Developmental Biology Center, University of California, Irvine 92697, USA
    Dev Biol 192:523-36. 1997
    ..Expression during later stages of budding, during head regeneration and the formation of ectopic heads, indicates a role in head formation. It is likely that budhead plays a critical role in head as well as axis formation in hydra...
  4. ncbi Spinalin, a new glycine- and histidine-rich protein in spines of Hydra nematocysts
    A W Koch
    Department of Biophysical Chemistry, Biozentrum, University of Basel, Klingelbergstrasse 70, Switzerland
    J Cell Sci 111:1545-54. 1998
    ....
  5. ncbi Identification of caspases and apoptosis in the simple metazoan Hydra
    M Cikala
    Zoologisches Institut, Universitat Munchen, Luisenstrasse 14, Munchen, 80333, Germany
    Curr Biol 9:959-62. 1999
    ..In the simple metazoan Hydra vulgaris, cell death regulates cell numbers [3] [4] [5]...
  6. ncbi HyAlx, an aristaless-related gene, is involved in tentacle formation in hydra
    K M Smith
    Developmental Biology Center, and Department of Developmental and Cell Biology, University of California, Irvine, CA 92697, USA
    Development 127:4743-52. 2000
    ..The different patterns of HyAlx expression during head regeneration and bud formation also provide support for a recent version of a reaction-diffusion model for axial patterning in hydra...
  7. pmc Trans-spliced leader addition to mRNAs in a cnidarian
    N A Stover
    Department of Biological Chemistry and the Developmental Biology Center, University of California, Irvine, CA 92697 1700, USA
    Proc Natl Acad Sci U S A 98:5693-8. 2001
    ..The presence and features of SL addition in the phylum Cnidaria raise interesting questions regarding the evolution of this process...
  8. ncbi Isolation of a putative peroxidase, a target for factors controlling foot-formation in the coelenterate hydra
    Sabine A H Hoffmeister-Ullerich
    Zentrum für Molekulare Neurobiologie, University of Hamburg, Germany
    Eur J Biochem 269:4597-606. 2002
    ..Transcripts of ppod2 are abundant in the whole animal with the exception of the hypostome, the tentacles, and the foot; the expression of ppod1 matches exactly the localization of the foot-specific peroxidase...
  9. ncbi Nowa, a novel protein with minicollagen Cys-rich domains, is involved in nematocyst formation in Hydra
    Ulrike Engel
    Institute of Zoology, Darmstadt University of Technology, 64287 Darmstadt, Germany
    J Cell Sci 115:3923-34. 2002
    ....
  10. ncbi Cloning and characterisation of PKB and PRK homologs from Hydra and the evolution of the protein kinase family
    Michaela Herold
    Ludwig Maximilians University Munich, Zoological Institute, Luisenstrasse 14, 80333 Munich, Germany
    Dev Genes Evol 212:513-9. 2002
    ..The precursor for these kinases must have contained N-terminal regulatory domains that were retained in fungal PRKs but subsequently partitioned between kinases of the PKC and PRK groups in metazoans...
  11. ncbi Molecular cloning and cellular distribution of two 14-3-3 isoforms from Hydra: 14-3-3 proteins respond to starvation and bind to phosphorylated targets
    Barbara Pauly
    Zoological Institute, Ludwig Maximilians University Munich, D 80333 14, Munich, Luisenstrasse, Germany
    Exp Cell Res 285:15-26. 2003
    ..Moreover, 14-3-3 protein is present in large amounts in food granules and from this we conclude that it performs functions which are associated with metabolism and food storage in Hydra...
  12. ncbi Hyzic, the Hydra homolog of the zic/odd-paired gene, is involved in the early specification of the sensory nematocytes
    Dirk Lindgens
    Molecular Cell Biology, Darmstadt University of Technology, Schnittspahnstrasse 10, 64287 Darmstadt, Germany
    Development 131:191-201. 2004
    ..Our results suggest, that genetic cascades of neural development may be conserved from Hydra to vertebrates, indicating that the molecular regulation of neural development evolved only once...
  13. ncbi Probable horizontal transfer of a gene between a protist and a cnidarian
    Robert E Steele
    Curr Biol 14:R298-9. 2004
  14. ncbi Hym-301, a novel peptide, regulates the number of tentacles formed in hydra
    Toshio Takahashi
    Developmental Biology Center, University of California, Irvine, CA 92697, USA
    Development 132:2225-34. 2005
    ..This indicates the range of expression of the gene appears to be controlled by this gradient. Thus, Hym-301 is involved in axial patterning in hydra, and specifically in the regulation of the number of tentacles formed...
  15. ncbi Foot differentiation and genomic plasticity in Hydra: lessons from the PPOD gene family
    Stefan Thomsen
    Zoological Institute, Christian Albrechts University, Kiel, Germany
    Dev Genes Evol 216:57-68. 2006
    ....
  16. pmc The innate immune repertoire in cnidaria--ancestral complexity and stochastic gene loss
    David J Miller
    ARC Centre of Excellence in Coral Reef Studies and Comparative Genomics Centre, James Cook University, Townsville, Queensland, Australia
    Genome Biol 8:R59. 2007
    ..Recently, whole genome sequences became available for two cnidarians, Hydra magnipapillata and Nematostella vectensis, and large expressed sequence tag (EST) datasets are available for these and for the coral Acropora millepora...
  17. ncbi Transgenic stem cells in Hydra reveal an early evolutionary origin for key elements controlling self-renewal and differentiation
    Konstantin Khalturin
    Zoological Institute, Christian Albrechts University, Olshausenstrasse 40, 24098 Kiel, Germany
    Dev Biol 309:32-44. 2007
    ....
  18. doi Evolution of complex structures: minicollagens shape the cnidarian nematocyst
    Charles N David
    Department Biologie II, Ludwig Maximilians Universitat, D 82152 Planegg Martinsried, Germany
    Trends Genet 24:431-8. 2008
    ..We hypothesize that novel CRD motifs alter minicollagen networks, leading to novel capsule structures and nematocyst types...
  19. pmc A novel gene family controls species-specific morphological traits in Hydra
    Konstantin Khalturin
    Zoological Institute, Christian Albrechts University, Kiel, Germany
    PLoS Biol 6:e278. 2008
    ..These results suggest that "novel" genes may be involved in the generation of species-specific morphological traits...
  20. doi Defining the origins of the NOD-like receptor system at the base of animal evolution
    Christina Lange
    Zoological Institute, Christian Albrechts University Kiel, Kiel, Germany
    Mol Biol Evol 28:1687-702. 2011
    ..These results add substantially to our understanding of the ancestral innate immune repertoire as well as providing the first insights into putative cytoplasmic defense mechanisms at the base of animal evolution...
  21. pmc Mini-collagens in hydra nematocytes
    E M Kurz
    Department of Zoology, University of Munich, Germany
    J Cell Biol 115:1159-69. 1991
    ..Electrophoretic characterization of nematocyst extracts allows resolution of small proline-rich polypeptides that correspond in size to the cloned sequences...
  22. ncbi A Dickkopf- 3-related gene is expressed in differentiating nematocytes in the basal metazoan Hydra
    Henning Fedders
    Zoological Institute, Christian Albrechts University Kiel, Olshausenstrasse 40, 24098, Kiel, Germany
    Dev Genes Evol 214:72-80. 2004
    ..They also suggest that vertebrate Dkk-1, 2 and 4 may have originated from a common ancestor gene of Dkk-3...
  23. doi Minicollagen-15, a novel minicollagen isolated from Hydra, forms tubule structures in nematocysts
    Patrizia Adamczyk
    Institute of Zoology, Department of Molecular Evolution and Genomics, Im Neuenheimer Feld 230, 69130 Heidelberg, Germany
    J Mol Biol 376:1008-20. 2008
    ..Our data provide evidence for evolutionary diversification among minicollagens, which probably facilitated alterations in the morphology of the nematocyst wall and tubule...
  24. doi Cilium evolution: identification of a novel protein, nematocilin, in the mechanosensory cilium of Hydra nematocytes
    Jung Shan Hwang
    Center for Information Biology and DDBJ, National Institute of Genetics, Mishima, Japan
    Mol Biol Evol 25:2009-17. 2008
    ..Thus, the evolution of a novel ciliary structure, which provides mechanical rigidity to the sensory cilium during the process of mechanoreception, is associated with the evolution of a novel protein...
  25. ncbi Expression of Cnox-2, a HOM/HOX homeobox gene in hydra, is correlated with axial pattern formation
    M A Shenk
    Developmental Biology Center, University of California, Irvine 92717 1700
    Development 117:657-67. 1993
    Cnox-2 is a HOM/HOX homeobox gene that we have identified in the simple metazoan Hydra vulgaris (Cnidaria: Hydrozoa)...
  26. ncbi Identification of a Hydra homologue of the beta-catenin/plakoglobin/armadillo gene family
    E Hobmayer
    Laboratory of Cell and Developmental Biology, University of Frankfurt, Frankfurt Main, Germany
    Gene 172:155-9. 1996
    ..This suggests that beta Ctn appeared very early in metazoan evolution, possibly when primitive multicellular animals started to form epithelial cell layers...
  27. ncbi Ultrastructural observations of adherent cell pairs in hydra vulgaris
    - Takaku
    Graduate School of Information Sciences, Tohoku University, Aoba, Sendai 980 8577, Japan and Photodynamics Research Center, The Institute of Physical and Chemical Research RIKEN, Nagamachi, Aoba, Sendai 982 0842, Japan
    J Exp Biol 202:2239-44. 1999
    Previous morphological studies of cell sorting in Hydra vulgaris have considered only clusters of cells...
  28. ncbi A head-activator binding protein is present in hydra in a soluble and a membrane-anchored form
    W Hampe
    Center for Molecular Neurobiology, University of Hamburg, Martinistr 52, D 20246 Hamburg, Germany
    Development 126:4077-86. 1999
    ..Secretion of HAB during regeneration and expression in regions of high determination potential hint at a role for HAB in regulating the concentration and range of action of head activator...
  29. ncbi WNT signalling molecules act in axis formation in the diploblastic metazoan Hydra
    B Hobmayer
    Department of Molecular Cell Biology, Zoological Institute, Darmstadt University of Technology, Germany
    Nature 407:186-9. 2000
    ..Our results indicate that Wnt signalling may be involved in axis formation in Hydra and support the idea that it was central in the evolution of axial differentiation in early multicellular animals...
  30. ncbi Universal occurrence of the vasa-related genes among metazoans and their germline expression in Hydra
    K Mochizuki
    Department of Genetics, The Graduate University for Advanced Studies, Mishima 411 8540, Japan
    Dev Genes Evol 211:299-308. 2001
    ..These results suggest that the vas-related genes occur universally among metazoans and that their expression in germline cells was established at least before cnidarian evolution...
  31. ncbi Identification and expression of HySmad1, a member of the R-Smad family of TGFbeta signal transducers, in the diploblastic metazoan Hydra
    B Hobmayer
    Department of Molecular Cell Biology, Zoological Institute, Darmstadt University of Technology, Schnittspahnstrasse 10, 64287 Darmstadt, Germany
    Dev Genes Evol 211:597-602. 2001
    ..This suggests that multiple functions of TGFbeta/Smad signaling might be conserved between diploblastic and triploblastic metazoans...
  32. pmc The phosphatidylserine receptor from Hydra is a nuclear protein with potential Fe(II) dependent oxygenase activity
    Mihai Cikala
    Department Biologie II, Ludwig Maximilians University Munich, Luisenstr, 14 D 80333 Munich, Germany
    BMC Cell Biol 5:26. 2004
    ..Surface exposure of phosphatidylserine is recognised by a specific receptor (phosphatidylserine receptor, PSR) and is required for phagocytosis of apoptotic cells by macrophages and fibroblasts...
  33. ncbi Unique catabolic pathway of glycosphingolipids in a hydrozoan, Hydra magnipapillata, involving endoglycoceramidase
    Yasuhiro Horibata
    Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Higashi ku, Fukuoka, Japan
    J Biol Chem 279:33379-89. 2004
    ..These results indicate that the EGCase is indispensable for the catabolic processing of dietary glycosphingolipids in hydra, demonstrating the unique catabolic pathway for glyosphingolipids in the animal...
  34. ncbi Evolution of gap junctions: the missing link?
    Haris Alexopoulos
    Curr Biol 14:R879-80. 2004
  35. ncbi Thypedin, the multi copy precursor for the hydra peptide pedin, is a beta-thymosin repeat-like domain containing protein
    D Herrmann
    Centre for Molecular Neurobiology, ZMNH, University of Hamburg, Martinistrasse 52, 20246 Hamburg, Germany
    Mech Dev 122:1183-93. 2005
    ..Since actin polymerisation and depolymerisation processes are known to take place during morphogenetic processes, these findings may hint at new aspects of the function of pedin and its precursor in pattern formation in hydra...
  36. doi Cloning of noggin gene from hydra and analysis of its functional conservation using Xenopus laevis embryos
    Kalpana Chandramore
    Zoology Group, Division of Animal Sciences, Agharkar Research Institute, Pune 411 004, India
    Evol Dev 12:267-74. 2010
    ..Our data indicate that BMP/Noggin antagonism predates the bilaterian divergence and is conserved during the evolution...
  37. doi The complete mitochondrial genome of Hydra vulgaris (Hydroida: Hydridae)
    Hong Chun Pan
    Laboratory of Molecular Evolution and Biodiversity, College of Life Sciences, Anhui Normal University, Wuhu, P R China and
    Mitochondrial DNA 25:418-9. 2014
    The complete mitochondrial genome of Hydra vulgaris (Hydroida: Hydridae) is composed of two linear DNA molecules...
  38. doi Eph receptors and ephrin class B ligands are expressed at tissue boundaries in Hydra vulgaris
    Susanne Tischer
    Department of Biology 2, Ludwig Maximilians Universitat Munchen, Germany
    Int J Dev Biol 57:759-65. 2013
    ..Here we have identified four Eph receptors and three class B ligands in the cnidarian Hydra vulgaris, indicating that those are the evolutionary older ones...
  39. doi Analysis of Hydra PIWI proteins and piRNAs uncover early evolutionary origins of the piRNA pathway
    Robyn S M Lim
    Temasek Life Sciences Laboratory, National University of Singapore, Singapore 117604, Singapore Department of Biological Sciences, National University of Singapore, Singapore 117543, Singapore
    Dev Biol 386:237-51. 2014
    ..These results indicate that various conserved features of PIWI proteins, the piRNA pathway, and their associations with the nuage were likely established before the evolution of bilaterians. ..
  40. doi Molecular cloning, sequence analysis, prokaryotic expression, and function prediction of foot-specific peroxidase in Hydra magnipapillata Chinese strain
    H C Pan
    College of Life Science, Anhui Normal University, Wuhu, Anhui, China
    Genet Mol Res 13:6610-22. 2014
    ..In conclusion, these cells might play an important role in strengthening the adsorbability of the basal disc to substrates. ..
  41. pmc A fast recoiling silk-like elastomer facilitates nanosecond nematocyst discharge
    ANNA BECKMANN
    Department of Molecular Evolution and Genomics, University of Heidelberg, Centre for Organismal Studies, Im Neuenheimer Feld 329, 69120, Heidelberg, Germany
    BMC Biol 13:3. 2015
    ..Hitherto, the molecular basis for the unusual biomechanical properties of nematocysts has been elusive, as their structure was mainly defined as a stress-resistant collagenous matrix...
  42. doi The aquatic impact of ionic liquids on freshwater organisms
    Susana P F Costa
    LAQV, REQUIMTE, Departamento de Ciencias Quimicas, Laboratório de Química Aplicada, Faculdade de Farmacia, Universidade do Porto, Rua Jorge Viterbo Ferreira, n 228, 4050 313 Porto, Portugal Electronic address
    Chemosphere 139:288-94. 2015
    ..used organic solvents was evaluated using freshwater organisms: Daphnia magna, Raphidocelis subcapitata and Hydra attenuata. The bioassays were performed by exposing the organisms to increasing concentrations of the ILs and observing ..
  43. pmc Cloning a Chymotrypsin-Like 1 (CTRL-1) Protease cDNA from the Jellyfish Nemopilema nomurai
    Yunwi Heo
    Department of Pharmacology and Toxicology, College of Veterinary Medicine, Gyeongsang National University, Jinju 660 701, Korea
    Toxins (Basel) 8:. 2016
    ..is evolutionarily more closely related to Actinopterygii than to Scyphozoan (Aurelia aurita) or Hydrozoan (Hydra vulgaris). The N...
  44. doi Two-step evolution of endosymbiosis between hydra and algae
    Masakazu Ishikawa
    Department of Genetics, SOKENDAI, Yata, Mishima, Shizuoka 411 8540, Japan Center for Information Biology, National Institute of Genetics, Yata, Mishima, Shizuoka 411 8540, Japan
    Mol Phylogenet Evol 103:19-25. 2016
    In the Hydra vulgaris group, only 2 of the 25 strains in the collection of the National Institute of Genetics in Japan currently show endosymbiosis with green algae...
  45. ncbi The Hydra regeneration assay reveals ecological risks in running waters: a new proposal to detect environmental teratogenic threats
    Lorenzo Traversetti
    Department of Sciences, University Rome Tre, V le G Marconi 446, Rome, 00146, Italy
    Ecotoxicology . 2016
    The regenerative ability of Hydra vulgaris was tested as potential biomarker for the development of a new eco-toxicological index...
  46. ncbi Cloning of a ras-related gene from Hydra which responds to head-specific signals
    T C Bosch
    Zoological Institute, University of Munich, Germany
    Gene 167:191-5. 1995
    ..Plenum Press, New York, NY, 1993, pp. 237-253]. The finding that Hydra ras2 expression is strongly dependent on a signal from the head provides the first evidence for ras expression being regulated in pattern formation...
  47. pmc Three different prohormones yield a variety of Hydra-RFamide (Arg-Phe-NH2) neuropeptides in Hydra magnipapillata
    D Darmer
    Department of Cell Biology and Anatomy, Zoological Institute, University of Copenhagen, Universitetsparken 15, DK 2100 Copenhagen O, Denmark
    Biochem J 332:403-12. 1998
    ..All of this shows that neuropeptide biosynthesis in the primitive metazoan Hydra is already rather complex...
  48. ncbi Sponge Pax cDNA related to Pax-2/5/8 and ancient gene duplications in the Pax family
    D Hoshiyama
    Department of Biophysics, Kyoto University Graduate School of Science, Kyoto 606 8502, Japan
    J Mol Evol 47:640-8. 1998
    ..Furthermore, the evolutionary rates of the Pax proteins have been shown to decrease with increasing organismal complexity during animal evolution...
  49. ncbi The structure and expression of a preprohormone of a neuropeptide, Hym-176 in Hydra magnipapillata
    S Yum
    Department of Developmental Genetics, National Institute of Genetics, Mishima, Japan
    FEBS Lett 439:31-4. 1998
    ..No signals were detected in the two extremities of the body, tentacles and basal disk. The expression pattern is correlated with the distribution of Hym-176 and its myoactive function...
  50. ncbi Extensive gene duplication in the early evolution of animals before the parazoan-eumetazoan split demonstrated by G proteins and protein tyrosine kinases from sponge and hydra
    H Suga
    Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto 606 8502 Japan
    J Mol Evol 48:646-53. 1999
    ....
  51. ncbi Enhancement of foot formation in Hydra by a novel epitheliopeptide, Hym-323
    N Harafuji
    Department of Genetics, The Graduate University for Advanced Studies, Mishima 411 8540, Japan
    Development 128:437-46. 2001
    ..Lateral transplantation experiments indicated that the foot activation potential was increased in the peptide-treated tissue. These results suggest that Hym-323 is a peptide involved in a foot-patterning process in Hydra...
  52. ncbi Epithelial interactions in Hydra: apoptosis in interspecies grafts is induced by detachment from the extracellular matrix
    Sergey G Kuznetsov
    Zoologisches Institut, Christian Albrechts Universitat zu Kiel, Germany
    J Exp Biol 205:3809-17. 2002
    ..We studied epithelial interactions between Hydra vulgaris and Hydra oligactis and show that a large number of apoptotic cells accumulate in the contact region of ..
  53. ncbi Dickkopf related genes are components of the positional value gradient in Hydra
    Rene Augustin
    Zoological Institute, Christian Albrechts University, Olshausenstrasse 40, 24098 Kiel, Germany
    Dev Biol 296:62-70. 2006
    ..Thus, similar to Dickkopf proteins in vertebrates, one of the functions of HyDkk1/2/4-C in hydra may be to antagonize Wnt signalling...
  54. ncbi The Wnt code: cnidarians signal the way
    C Guder
    Department of Molecular Evolution and Genomics, University of Heidelberg, Heidelberg, Germany
    Oncogene 25:7450-60. 2006
    ....
  55. ncbi A novel neuropeptide (FRamide) family identified by a peptidomic approach in Hydra magnipapillata
    Eisuke Hayakawa
    Department of Developmental Genetics, National Institute of Genetics, Mishima, Shizuoka, Japan
    FEBS J 274:5438-48. 2007
    ..In contrast, FRamide-2 evoked body column contraction. These results suggest that both of the neuropeptides directly act on epithelial cells as neurotransmitters and regulate body movement in an axial direction...
  56. pmc Ornithine decarboxylase antizyme finder (OAF): fast and reliable detection of antizymes with frameshifts in mRNAs
    Michael Bekaert
    School of Biology and Environmental Science, University College Dublin, Belfield, Dublin 4, Ireland
    BMC Bioinformatics 9:178. 2008
    ..This manuscript describes a rapid and accurate computer tool for antizyme CDS detection that requires minimal human involvement...
  57. pmc Characterization of taxonomically restricted genes in a phylum-restricted cell type
    Sabine Milde
    Zoological Institute, Christian Albrechts University Kiel, Kiel, Germany
    Genome Biol 10:R8. 2009
    ....
  58. doi Further characterization of the PW peptide family that inhibits neuron differentiation in Hydra
    Toshio Takahashi
    Suntory Institute for Bioorganic Research, Osaka, 618 8503, Japan
    Dev Genes Evol 219:119-29. 2009
    ..Together with Hym-355, the PW family peptides mediate communication between neurons and epithelial cells and thereby maintain a specific density of neurons in Hydra...
  59. doi beta-catenin plays a central role in setting up the head organizer in hydra
    Lydia Gee
    Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA
    Dev Biol 340:116-24. 2010
    ....
  60. pmc The novel peptide HEADY specifies apical fate in a simple radially symmetric metazoan
    J U Lohmann
    Zoological Institute, University of Jena, 07743 Jena, Germany
    Genes Dev 14:2771-7. 2000
    ..Thus, the HEADY peptide acts as developmental switch to pattern the apical-basal axis of Hydra, providing a first insight into how initial asymmetry is specified in lower metazoan animals...
  61. ncbi An ancient Wnt-Dickkopf antagonism in Hydra
    Corina Guder
    Molecular Evolution and Genomics, Heidelberg University, Im Neuenheimer Feld 230, 69120 Heidelberg, Germany
    Development 133:901-11. 2006
    ..Based on the corresponding expression patterns of hydkk1/2/4 and neuronal genes, we suggest that the body column of Hydra is a neurogenic environment suppressing Wnt signalling and facilitating neurogenesis...
  62. pmc Activity of the novel peptide arminin against multiresistant human pathogens shows the considerable potential of phylogenetically ancient organisms as drug sources
    Rene Augustin
    Zoological Institute, Christian Albrechts University Kiel, Kiel, Germany
    Antimicrob Agents Chemother 53:5245-50. 2009
    ..Our data suggest that ancient metazoan organisms such as Hydra hold promise for the detection of novel antimicrobial molecules and the treatment of infections caused by multiresistant bacteria...
  63. ncbi Organophosphate nerve agent toxicity in Hydra attenuata
    Karin T Lum
    Department of Chemistry, P O Box 30012, Texas A and M University, College Station, Texas 77842 3012, USA
    Chem Res Toxicol 16:953-7. 2003
    The toxicity for analogues of sarin (GB), soman (GD), and VX was evaluated using Hydra attenuata as a model organism...
  64. ncbi Signalling by the FGFR-like tyrosine kinase, Kringelchen, is essential for bud detachment in Hydra vulgaris
    Stefanie Sudhop
    Philipps University Marburg, FB 17, Morphology and Evolution of Invertebrates, Karl von Frisch Strasse 8, 35032 Marburg, Germany
    Development 131:4001-11. 2004
    ..Although Kringelchen groups with the FGFR family, it is not known whether this protein is able to bind FGFs, which have not been isolated from Hydra so far...
  65. ncbi [Effects of arachidonoyl dopamine, haloperidol, and their mixtures on regeneration of freshwater Hydra attenuata]
    L N Markova
    Ontogenez 35:367-74. 2004
    ..Possible mechanisms underlying the effects of these substances are discussed...
  66. ncbi Prevention of zearalenone-induced hyperestrogenism in prepubertal mice
    Evans Afriyie-Gyawu
    Department of Veterinary Integrative Biosciences, Texas A and M University, College Station, Texas 77843 4458, USA
    J Toxicol Environ Health A 68:353-68. 2005
    ..hydra bioassay suggested that the addition of either AC or HEC effectively decreased the effects of ZEN on Hydra attenuata without toxicity, as was observed with the use of either CP-LPHM or HDTMA-LPHM...
  67. ncbi Quantification of cell-cycle distribution and mitotic index in Hydra by flow cytometry
    H Ulrich
    Department of Biochemistry, Instituto de Quimica, Universidade de Sao Paulo, Brazil
    Cell Prolif 38:63-75. 2005
    ..of flow cytometry (FCM) to analyse cell-cycle distribution and mitotic cells in Hydra oligactis and Hydra vulgaris is demonstrated. The freshwater polyps H. vulgaris and H...
  68. ncbi Control of foot differentiation in Hydra: phylogenetic footprinting indicates interaction of head, bud and foot patterning systems
    S Siebert
    Zoological Institute, Christian Albrechts University of Kiel, Am Botanischen Garten 1 9, 24118 Kiel, Germany
    Mech Dev 122:998-1007. 2005
    ..By phylogenetic footprinting we compared the CnNK-2 5'-flanking sequence from two closely related species, Hydra vulgaris and Hydra oligactis...
  69. ncbi Discovery of genes expressed in Hydra embryogenesis
    Grigory Genikhovich
    Zoological Institute, Christian Albrechts University of Kiel, Am Botanischen Garten 1 9, 24118 Kiel, Germany
    Dev Biol 289:466-81. 2006
    ..213, 445-455). Here, we describe an unbiased screening strategy to identify genes that are relevant to Hydra vulgaris embryogenesis...
  70. ncbi Molecular characterization of phospholipid hydroperoxide glutathione peroxidases from Hydra vulgaris
    Bhagirathi Dash
    Faculty of Toxicology, Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, College Station, TX 77843, USA
    Gene 381:1-12. 2006
    ..HvGPx41) and nuclear (HvGPx42) phospholipid hydroperoxide glutathione peroxidase were isolated from Hydra vulgaris. The cDNA sequences share total identity in their 3'-end and differ in their 5'-end...
  71. doi The Hydra FGFR, Kringelchen, partially replaces the Drosophila Heartless FGFR
    Anja Rudolf
    Faculty of Biology, Morphology and Evolution of Invertebrates, Philipps Universitat Marburg, Karl von Frisch Str 8, 35032, Marburg, Germany
    Dev Genes Evol 223:159-69. 2013
    ..to investigate their functional conservation, we asked whether the Kringelchen FGFR in the freshwater polyp Hydra vulgaris, is able to functionally replace FGFR in fly embryos...
  72. pmc RNAseq versus genome-predicted transcriptomes: a large population of novel transcripts identified in an Illumina-454 Hydra transcriptome
    Yvan Wenger
    Department of Genetics and Evolution, Institute of Genetics and Genomics in Geneva iGE3, University of Geneva, Geneva, Switzerland
    BMC Genomics 14:204. 2013
    ..present the assembly of the most complete Hydra transcriptome to date along with a comparative analysis of the specific features of RNAseq and genome-predicted transcriptomes currently available in the freshwater hydrozoan Hydra vulgaris.
  73. pmc Hymyc1 downregulation promotes stem cell proliferation in Hydra vulgaris
    Alfredo Ambrosone
    Istituto di Cibernetica E Caianiello, Consiglio Nazionale delle Ricerche, Pozzuoli, Italy
    PLoS ONE 7:e30660. 2012
    ....
  74. pmc Molecular characterization of a catalase from Hydra vulgaris
    Bhagirathi Dash
    Faculty of Toxicology, Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, College Station, TX 77843, USA
    Gene 501:144-52. 2012
    ..In this work an apparent full length cDNA sequence coding for a catalase (HvCatalase) was isolated from Hydra vulgaris using 3'- and 5'- (RLM) RACE approaches...
  75. ncbi Coordinated modulation of cellular signaling through ligand-gated ion channels in Hydra vulgaris (Cnidaria, Hydrozoa)
    Paola Pierobon
    Istituto di Cibernetica E Caianiello C N R, Naples, Italy
    Int J Dev Biol 56:551-65. 2012
    ....
  76. doi Genes encoding cytoplasmic intermediate filament proteins of vertebrates revisited: identification of a cytoplasmic intermediate filament protein in the sea anemone Nematostella
    Alexander Zimek
    Max Planck Institute for Biophysical Chemistry, Goettingen, Germany
    Eur J Cell Biol 91:809-17. 2012
    ..Our data reveal a relationship of cytovec with Hydra vulgaris nematocilins A and B that also lack a CAAX box...
  77. pmc Deep sequencing reveals unique small RNA repertoire that is regulated during head regeneration in Hydra magnipapillata
    Srikar Krishna
    Institute for Stem Cell Biology and Regenerative Medicine, National Centre for Biological Sciences, GKVK Campus, Bellary Road, Bangalore 560065, India
    Nucleic Acids Res 41:599-616. 2013
    ..Less than 50% are conserved across two different strains of Hydra vulgaris tested in this study, indicating a highly diverse nature of hydra miRNAs in contrast to bilaterian miRNAs...
  78. doi Methodological approaches for nanotoxicology using cnidarian models
    Alfredo Ambrosone
    Istituto di Cibernetica E Caianiello, Consiglio Nazionale delle Ricerche, Pozzuoli, Italy
    Toxicol Mech Methods 23:207-16. 2013
    ..The proliferation of molecular and genomic tools, including the whole genomic sequence of the freshwater polyp Hydra vulgaris and the starlet sea anemone Nematostella vectensis, further enhances the promise of these species to ..
  79. ncbi Extracellular matrix (mesoglea) of Hydra vulgaris. II. Influence of collagen and proteoglycan components on head regeneration
    M P Sarras
    Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City 66103
    Dev Biol 148:495-500. 1991
    ..the present study was undertaken to analyze the role of mesoglea components during head regeneration in Hydra vulgaris. Studies were conducted that utilized drugs that affect collagen processing or secondary collagen structure (..
  80. ncbi Processing specificity and biosynthesis of the Drosophila melanogaster convertases dfurin1, dfurin1-CRR, dfurin1-X, and dfurin2
    I De Bie
    J A DeSève Laboratory of Biochemical Neuroendocrinology, Clinical Research Institute of Montreal, Quebec, Canada
    J Biol Chem 270:1020-8. 1995
    ..A similar molecular diversity is also observed for the convertases of Hydra vulgaris, Caenorhabditis elegans, and Drosophila melanogaster...
  81. ncbi Cell-extracellular matrix interactions under in vivo conditions during interstitial cell migration in Hydra vulgaris
    X Zhang
    Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City 66160 7400
    Development 120:425-32. 1994
    ..beta-xyloside treatment had no effect on interstitial cell migration. These results indicate the potential importance of cell-extracellular matrix interactions during in vivo I-cell migration in hydra...
  82. ncbi Extracellular matrix (mesoglea) of Hydra vulgaris III. Formation and function during morphogenesis of hydra cell aggregates
    M P Sarras
    Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City 66160
    Dev Biol 157:383-98. 1993
    ..These studies indicate that (1) mesoglea formation is rapid and precedes morphogenetic processes during aggregate development, and (2) formation of mesoglea is essential for normal morphogenesis of hydra cell aggregates...
  83. ncbi Stepwise transfer from high to low lithium concentrations increases the head-forming potential in Hydra vulgaris and possibly activates the PI cycle
    M Hassel
    Zoologisches Institut II der Universitaet, Heidelberg, Germany
    Dev Biol 177:439-48. 1996
    Lithium ions affect pattern formation in the freshwater polyp Hydra vulgaris in a complex manner...
  84. ncbi Head formation at the basal end and mirror-image pattern duplication in Hydra vulgaris
    W A Muller
    Zoological Institute, Heidelberg University, Germany
    Int J Dev Biol 40:1119-31. 1996
    ..4) The basal head in turn organizes a mirror-image duplication of the body pattern. In pattern regulation, Hydra follows rules of intercalation known from other organisms...
  85. ncbi Hydroperoxides mediate lithium effects on regeneration in Hydra
    H Jantzen
    Zoologisches Institut, Universitat Heidelberg, Germany
    Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 119:165-75. 1998
    ..First, the perturbation of pattern formation is strikingly stronger in the strain Hydra vulgaris than in Hydra magnipapillata, and similar strain-specific differences are found in the long lasting ..
  86. ncbi The novel signal peptides, pedibin and Hym-346, lower positional value thereby enhancing foot formation in hydra
    A Grens
    Department of Developmental and Cell Biology, University of California, Irvine, California 92697 2300, USA
    Development 126:517-24. 1999
    ..Two novel peptides, pedibin and Hym-346, that are closely related to one another have been isolated from Hydra vulgaris and Hydra magnipapillata...
  87. ncbi Appearance and disappearance of Syk family protein-tyrosine kinase genes during metazoan evolution
    R E Steele
    Department of Biological Chemistry, University of California, Irvine 92697 1700, USA
    Gene 239:91-7. 1999
    ..Surprisingly, we have found that Hydra vulgaris, a member of the early diverging animal phylum Cnidaria, contains a gene encoding a Syk kinase...
  88. ncbi Acute toxicity assessment of Polish (waste) water with a microplate-based Hydra attenuata assay: a comparison with the Microtox test
    M Pardos
    Institute F A Forel, University of Geneva, Versoix, Switzerland
    Sci Total Environ 243:141-8. 1999
    The use of Hydra attenuata in acute toxicity assessment is a potentially useful tool in (waste) water biomonitoring. The purpose of this study was to compare the sensitivity of H...
  89. ncbi Initial homotypic cell pair adhesion in regenerating Hydra facilitates subsequent adhesion of homotypic cells
    Y Takaku
    Graduate School of Information Sciences, Tohoku University, Sendai, Japan
    Naturwissenschaften 87:177-9. 2000
    In Hydra vulgaris at the level of dissociated single cells endodermal cells adhere to each other more readily than to ectodermal cells at the initial adhesion...
  90. ncbi [Effect of inhibitors of synthesis of dopamine and its antagonists on Hydra attenuata regeneration]
    T V Ostroumova
    Moscow State University, Russia, Moscow, 119899
    Ross Fiziol Zh Im I M Sechenova 86:1246-54. 2000
    ..The apical and basal fragments did not suffer. The role of neurotransmitters in the hydra morphogenesis is discussed...
  91. ncbi The acute and chronic toxicity of cadmium and zinc to two hydra species
    D A Holdway
    Department of Biotechnology and Environmental Biology, RMIT University, Bundoora West Campus, GPO Box 71, Bundoora, Melbourne, VIC 3083, Australia
    Environ Toxicol 16:557-65. 2001
    The potential of two hydra species, Hydra vulgaris (pink) and Hydra viridissima (green), for use as invertebrate models for toxicity testing of waterborne metals was investigated...
  92. ncbi Putative glycine receptors in Hydra: a biochemical and behavioural study
    P Pierobon
    Consiglio Nazionale delle Ricerche, Istituto di Cibernetica E Caianiello, Comprensorio Olivetti, Building 70, Via Campi Flegrei 34, I 80078 Pozzuoli, Naples, Italy
    Eur J Neurosci 14:1659-66. 2001
    ..Here we report the identification and characterization of glycine receptors in the freshwater polyp Hydra vulgaris (Cnidaria, Hydrozoa) by biochemical and behavioural studies...
  93. ncbi Toxicity of 17alpha-ethinylestradiol and bisphenol A to the freshwater Cnidarian Hydra vulgaris
    D Pascoe
    School of Biosciences, Main Building, Cardiff University, P O Box 915, Cardiff CF10 3TL, UK
    Arch Environ Contam Toxicol 43:56-63. 2002
    ..There is also concern that such chemicals may be damaging to invertebrates. In this study, Hydra vulgaris, a member of the Cnidaria, an evolutionarily primitive group of invertebrates present before the divergence of ..
  94. ncbi A novel nucleolar biomarker in plant and animal cells for assessment of substance cytotoxicity
    V V Arkhipchuk
    Institute of Colloid Chemistry and Water Chemistry, Ukrainian Academy of Sciences, Vernadsky Boulevard 42, 03680, Kiev 142, Ukraine
    Environ Toxicol 17:187-94. 2002
    ..on cells of animal and plant test organisms: onion (Allium cepa), lettuce (Lactuca sativa), and hydra (Hydra attenuata)...
  95. ncbi Overview of results from the WaterTox intercalibration and environmental testing phase II program: Part 1, statistical analysis of blind sample testing
    A Ronco
    Faculty of Sciences, National University of La Plata, Argentina
    Environ Toxicol 17:232-40. 2002
    ..solutions of unknown composition to participating laboratories) using the following battery: Daphnia magna, Hydra attenuata, seed root inhibition with Lactuca sativa, and Selenastrum capricornutum...
  96. ncbi Quality of water types in Ukraine evaluated by WaterTox bioassays
    V V Arkhipchuk
    Institute of Colloid Chemistry and Water Chemistry, Ukrainian Academy of Sciences, Vernadsky Boulevard 42, 03680, Kiev 142, Ukraine
    Environ Toxicol 17:250-7. 2002
    ..and tap water was analyzed using the basic set of WaterTox bioassays [Daphnia (Daphnia magna), Hydra (Hydra attenuata), and lettuce (Lactuca sativa)] as well as two additional bioassays, onion (Allium cepa) and microalga (..
  97. ncbi The effects of dopamine synthesis inhibitors and dopamine antagonists on regeneration in the hydra Hydra attenuata
    T V Ostroumova
    M V Lomonosov Moscow State University, Vorob ev Heights, Russia
    Neurosci Behav Physiol 32:293-8. 2002
    ..blockers (haloperidol and spiperone) on the regeneration of apical, gastral, and basal fragments of the hydra Hydra attenuata were studied...
  98. ncbi Immunocytochemically defined populations of neurons progressively increase in size through embryogenesis of Hydra vulgaris
    Gordon B Brumwell
    Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana 46556, USA
    Biol Bull 203:70-9. 2002
    ..However, the density of neurons in each of these populations fell. These data do not support the hypothesis that large-scale culling of neurons during development, frequently found in other animals, occurs in hydra...
  99. ncbi QSAR modeling of the adult and developmental toxicity of glycols, glycol ethers and xylenes to Hydra attenuata
    J Devillers
    CTIS, Rillieux La Pape, France
    SAR QSAR Environ Res 13:555-66. 2002
    ..to describe glycols, glycol ethers, and xylenes characterized by their adult and developmental toxicities to Hydra attenuata. A PLS regression analysis was employed to derive a QSAR model allowing to simulate both endpoints...
  100. ncbi PLS-QSAR of the adult and developmental toxicity of chemicals to Hydra attenuata
    J Devillers
    CTIS, 3 Chemin de la Gravière, 69140 Rillieux La Pape, France
    SAR QSAR Environ Res 13:705-12. 2002
    ..were used to describe 30 organic chemicals characterized by their adult and developmental toxicities to Hydra attenuata. A PLS regression analysis was successfully employed to derive a QSAR model allowing the simulation of both ..
  101. ncbi Do pharmaceuticals affect freshwater invertebrates? A study with the cnidarian Hydra vulgaris
    David Pascoe
    School of Biosciences, Cardiff University, PO Box 915, Cardiff CF10 3TL, UK
    Chemosphere 51:521-8. 2003
    ..bendroflumethiazide, furosemide, atenolol, diazepam, digoxin, amlodipine were assessed using the cnidarian Hydra vulgaris. In a 7 day exposure period there were no effects on survival at concentrations up to 1...

Research Grants3

  1. Daniel E Martinez; Fiscal Year: 2014
    DESCRIPTION (provided by applicant): Existing data suggest that the invertebrate species Hydra vulgaris does not show increased mortality with age. Interestingly, a closely related species, H...
  2. MODEL FOR EPITHELIAL/BASEMENT MEMBRANE INTERACTIONS
    MICHAEL SARRAS; Fiscal Year: 1992
    ..This model has been developed from the invertebrate, Hydra vulgaris which is structurally reduced to an epithelial bilayer with an intervening basement membrane (mesoglea)...
  3. A MODEL FOR BASEMENT MEMBRANE THICKENING IN DIABETES
    MICHAEL SARRAS; Fiscal Year: 1991
    ..This model was developed using the Cnidarian, Hydra vulgaris. The proposed project will utilize this in vivo model to determine if glucose-mediated basement membrane ..

Patents10

  1. Benzo[a]pyrene responsive genes in Hydra magnipapillata and the method for diagnosing aquatic environment pollution using the same
    Patent Number: KR1020140114662-A; Date:2014-09-29
  2. Perfluorooctane sulfonate responsive genes in Hydra magnipapillata and the method for diagnosing aquatic environment pollution using the same
    Patent Number: KR1020140114663-A; Date:2014-09-29
  3. Biological effect monitoring by means of transgenic hydra
    Patent Number: WO2009015623-A1; Date:2009-02-05
  4. Peptide antibiotic made of hydra and coding gene
    Patent Number: WO2009067968-A1; Date:2009-06-04
  5. Process for the production of lutein
    Patent Number: EP2096177-A2; Date:2009-09-02
  6. Plants with increased yield (nue)
    Patent Number: WO2010046221-A1; Date:2010-04-29
  7. No title supplied
    Patent Number: WO2010063250-A1; Date:2010-06-10
  8. Process for the control of production of fine chemicals
    Patent Number: EP2199304-A1; Date:2010-06-23
  9. Proteins associated with abiotic stress response and homologs
    Patent Number: EP2221382-A2; Date:2010-08-25
  10. Mutant Endoglycoceramidases With Enhanced Synthetic Activity
    Patent Number: JP2008502329-A; Date:2008-01-31