Gumboro virus

Summary

Alias: Infectious bursal disease virus, Avian infectious bursal disease virus, Infectious bursal disease virus of chickens, infectious bursal disease virus IBDV, IBDV

Top Publications

  1. Li Z, Wang Y, Li X, Li X, Cao H, Zheng S. Critical roles of glucocorticoid-induced leucine zipper in infectious bursal disease virus (IBDV)-induced suppression of type I Interferon expression and enhancement of IBDV growth in host cells via interaction with VP4. J Virol. 2013;87:1221-31 pubmed publisher
    ..bursal disease (IBD) is an acute, highly contagious, and immunosuppressive avian disease caused by IBD virus (IBDV)...
  2. Letzel T, Mundt E, Gorbalenya A. Evidence for functional significance of the permuted C motif in Co2+-stimulated RNA-dependent RNA polymerase of infectious bursal disease virus. J Gen Virol. 2007;88:2824-33 pubmed publisher
    Segment B of bisegmented infectious bursal disease virus (IBDV) encodes virus protein 1 (VP1), possessing RNA-dependent RNA polymerase (RdRp) activity...
  3. Qi X, Gao H, Gao Y, Qin L, Wang Y, Gao L, et al. Naturally occurring mutations at residues 253 and 284 in VP2 contribute to the cell tropism and virulence of very virulent infectious bursal disease virus. Antiviral Res. 2009;84:225-33 pubmed publisher
    b>Infectious bursal disease virus (IBDV) is responsible for the highly contagious infectious bursal disease in chickens...
  4. Pan J, Lin L, Tao Y. Self-guanylylation of birnavirus VP1 does not require an intact polymerase activity site. Virology. 2009;395:87-96 pubmed publisher
    ..The guanylylation site was further mapped to the VP1 N-terminal domain. Our results support a mechanism in which VP1 self-guanylylation is catalyzed by a novel active site different from the polymerase active site...
  5. Wu Y, Hong L, Ye J, Huang Z, Zhou J. The VP5 protein of infectious bursal disease virus promotes virion release from infected cells and is not involved in cell death. Arch Virol. 2009;154:1873-82 pubmed publisher
    The VP5 protein of infectious bursal disease virus (IBDV) was shown in previous reports to be involved in the cytopathogenicity of IBDV...
  6. He Z, Chen X, Fu M, Tang J, Li X, Cao H, et al. Infectious bursal disease virus protein VP4 suppresses type I interferon expression via inhibiting K48-linked ubiquitylation of glucocorticoid-induced leucine zipper (GILZ). Immunobiology. 2017;: pubmed publisher
    ..Our previous study showed that infectious bursal disease virus (IBDV) inhibited type I interferon production via interaction of VP4 with cellular glucocorticoid-..
  7. Farhanah M, Yasmin A, Mat Isa N, Hair Bejo M, Ideris A, Powers C, et al. Bursal transcriptome profiling of different inbred chicken lines reveals key differentially expressed genes at 3 days post-infection with very virulent infectious bursal disease virus. J Gen Virol. 2017;: pubmed publisher
    ..immune response genes of inbred chickens with different genetic backgrounds, following very virulent infectious bursal disease virus (vvIBDV) infection are poorly characterized...
  8. Zhang L, Li H, Chen Y, Gao X, Lu Z, Gao L, et al. The down-regulation of casein kinase 1 alpha as a host defense response against infectious bursal disease virus infection. Virology. 2017;512:211-221 pubmed publisher
    b>Infectious bursal disease virus (IBDV) is an important immunosuppressive virus of chickens. Although the gene functions of IBDV have been well characterized, the host responses during IBDV infection remain much poor...
  9. Dey S, Chellappa M, Pathak D, Gaikwad S, Yadav K, Ramakrishnan S, et al. Newcastle Disease Virus Vectored Bivalent Vaccine against Virulent Infectious Bursal Disease and Newcastle Disease of Chickens. Vaccines (Basel). 2017;5: pubmed publisher
    ..virus and another recombinant NDV harboring the major capsid protein VP2 gene of a very virulent infectious bursal disease virus (IBDV); namely rNDV-F and rNDV-F/VP2, respectively, were generated using the NDV F strain...
  10. de Wit J, Cazaban C, Dijkman R, Ramon G, Gardin Y. Detection of different genotypes of infectious bronchitis virus and of infectious bursal disease virus in European broilers during an epidemiological study in 2013 and the consequences for the diagnostic approach. Avian Pathol. 2017;:1-12 pubmed publisher
    ..this survey also provided valuable information about the replication of IBD vaccines and subsequent infectious bursal disease virus (IBDV) antibody responses under field conditions...

Detail Information

Publications30

  1. Li Z, Wang Y, Li X, Li X, Cao H, Zheng S. Critical roles of glucocorticoid-induced leucine zipper in infectious bursal disease virus (IBDV)-induced suppression of type I Interferon expression and enhancement of IBDV growth in host cells via interaction with VP4. J Virol. 2013;87:1221-31 pubmed publisher
    ..bursal disease (IBD) is an acute, highly contagious, and immunosuppressive avian disease caused by IBD virus (IBDV)...
  2. Letzel T, Mundt E, Gorbalenya A. Evidence for functional significance of the permuted C motif in Co2+-stimulated RNA-dependent RNA polymerase of infectious bursal disease virus. J Gen Virol. 2007;88:2824-33 pubmed publisher
    Segment B of bisegmented infectious bursal disease virus (IBDV) encodes virus protein 1 (VP1), possessing RNA-dependent RNA polymerase (RdRp) activity...
  3. Qi X, Gao H, Gao Y, Qin L, Wang Y, Gao L, et al. Naturally occurring mutations at residues 253 and 284 in VP2 contribute to the cell tropism and virulence of very virulent infectious bursal disease virus. Antiviral Res. 2009;84:225-33 pubmed publisher
    b>Infectious bursal disease virus (IBDV) is responsible for the highly contagious infectious bursal disease in chickens...
  4. Pan J, Lin L, Tao Y. Self-guanylylation of birnavirus VP1 does not require an intact polymerase activity site. Virology. 2009;395:87-96 pubmed publisher
    ..The guanylylation site was further mapped to the VP1 N-terminal domain. Our results support a mechanism in which VP1 self-guanylylation is catalyzed by a novel active site different from the polymerase active site...
  5. Wu Y, Hong L, Ye J, Huang Z, Zhou J. The VP5 protein of infectious bursal disease virus promotes virion release from infected cells and is not involved in cell death. Arch Virol. 2009;154:1873-82 pubmed publisher
    The VP5 protein of infectious bursal disease virus (IBDV) was shown in previous reports to be involved in the cytopathogenicity of IBDV...
  6. He Z, Chen X, Fu M, Tang J, Li X, Cao H, et al. Infectious bursal disease virus protein VP4 suppresses type I interferon expression via inhibiting K48-linked ubiquitylation of glucocorticoid-induced leucine zipper (GILZ). Immunobiology. 2017;: pubmed publisher
    ..Our previous study showed that infectious bursal disease virus (IBDV) inhibited type I interferon production via interaction of VP4 with cellular glucocorticoid-..
  7. Farhanah M, Yasmin A, Mat Isa N, Hair Bejo M, Ideris A, Powers C, et al. Bursal transcriptome profiling of different inbred chicken lines reveals key differentially expressed genes at 3 days post-infection with very virulent infectious bursal disease virus. J Gen Virol. 2017;: pubmed publisher
    ..immune response genes of inbred chickens with different genetic backgrounds, following very virulent infectious bursal disease virus (vvIBDV) infection are poorly characterized...
  8. Zhang L, Li H, Chen Y, Gao X, Lu Z, Gao L, et al. The down-regulation of casein kinase 1 alpha as a host defense response against infectious bursal disease virus infection. Virology. 2017;512:211-221 pubmed publisher
    b>Infectious bursal disease virus (IBDV) is an important immunosuppressive virus of chickens. Although the gene functions of IBDV have been well characterized, the host responses during IBDV infection remain much poor...
  9. Dey S, Chellappa M, Pathak D, Gaikwad S, Yadav K, Ramakrishnan S, et al. Newcastle Disease Virus Vectored Bivalent Vaccine against Virulent Infectious Bursal Disease and Newcastle Disease of Chickens. Vaccines (Basel). 2017;5: pubmed publisher
    ..virus and another recombinant NDV harboring the major capsid protein VP2 gene of a very virulent infectious bursal disease virus (IBDV); namely rNDV-F and rNDV-F/VP2, respectively, were generated using the NDV F strain...
  10. de Wit J, Cazaban C, Dijkman R, Ramon G, Gardin Y. Detection of different genotypes of infectious bronchitis virus and of infectious bursal disease virus in European broilers during an epidemiological study in 2013 and the consequences for the diagnostic approach. Avian Pathol. 2017;:1-12 pubmed publisher
    ..this survey also provided valuable information about the replication of IBD vaccines and subsequent infectious bursal disease virus (IBDV) antibody responses under field conditions...
  11. Jackwood D, Sreedevi B, LeFever L, Sommer Wagner S. Studies on naturally occurring infectious bursal disease viruses suggest that a single amino acid substitution at position 253 in VP2 increases pathogenicity. Virology. 2008;377:110-6 pubmed publisher
    Three classic IBDV strains were previously isolated from commercial layer chicken flocks and shown to be phylogenetically related to vaccine strains but pathogenic in susceptible chickens...
  12. Wang H, Shan S, Wang S, Zhang H, Ma L, Hu L, et al. Fused IgY Fc and Polysaccharide Adjuvant Enhanced the Immune Effect of the Recombinant VP2 and VP5 Subunits-A Prospect for Improvement of Infectious Bursal Disease Virus Subunit Vaccine. Front Microbiol. 2017;8:2258 pubmed publisher
    b>Infectious bursal disease virus (IBDV) is a highly contagious pathogen that causes damage in lymphoid organs and remains a threat to the poultry industry worldwide...
  13. Dulwich K, Giotis E, Gray A, Nair V, Skinner M, Broadbent A. Differential gene expression in chicken primary B cells infected ex vivo with attenuated and very virulent strains of infectious bursal disease virus (IBDV). J Gen Virol. 2017;: pubmed publisher
    b>Infectious bursal disease virus (IBDV) belongs to the family Birnaviridae and is economically important to the poultry industry worldwide...
  14. Ye C, Wang Y, Zhang E, Han X, Yu Z, Liu H. VP1 and VP3 are required and sufficient for translation initiation of uncapped IBDV genomic dsRNA. J Virol. 2017;: pubmed publisher
    b>Infectious bursal disease virus (IBDV) is a bi-segmented double-strand RNA (dsRNA) virus of the Birnaviridae family...
  15. Pascual E, Mata C, Carrascosa J, Castón J. Assembly/disassembly of a complex icosahedral virus to incorporate heterologous nucleic acids. J Phys Condens Matter. 2017;: pubmed publisher
    ..Here we address the assembly dynamics of infectious bursal disease virus (IBDV), a complex icosahedral virus...
  16. Soubies S, Courtillon C, Abed M, Amelot M, Keita A, Broadbent A, et al. Propagation and titration of infectious bursal disease virus, including non-cell-culture-adapted strains, using ex vivo-stimulated chicken bursal cells. Avian Pathol. 2017;:1-10 pubmed publisher
    b>Infectious bursal disease virus (IBDV) is a Birnaviridae family member of economic importance for poultry...
  17. Shehata A, Sultan H, Halami M, Talaat S, Vahlenkamp T. Molecular characterization of very virulent infectious bursal disease virus strains circulating in Egypt from 2003 to 2014. Arch Virol. 2017;162:3803-3815 pubmed publisher
    In the present study, four very virulent infectious bursal disease virus (vvIBDV) isolates from flocks of chickens with vaccination failure in Egypt in 2003, 2007, 2010 and 2014 were characterized...
  18. Ou C, Wang Q, Yu Y, Zhang Y, Ma J, Kong X, et al. Chemokine receptor CCR5 and CXCR4 might influence virus replication during IBDV infection. Microb Pathog. 2017;107:122-128 pubmed publisher
    ..whether they will influence the process of T cell infiltration into bursa of Fabricius during infectious bursal disease virus (IBDV) infection is unclear...
  19. Wang M, Pan Q, Lu Z, Li K, Gao H, Qi X, et al. An optimized, highly efficient, self-assembled, subvirus-like particle of infectious bursal disease virus (IBDV). Vaccine. 2016;34:3508-14 pubmed publisher
    b>Infectious bursal disease virus (IBDV) causes immunosuppression in young chickens, leading to increased susceptibility to other diseases and a reduction in the immune response to other vaccines...
  20. Yu F, Ren X, Wang Y, Qi X, Song J, Gao Y, et al. A single amino acid V4I substitution in VP1 attenuates virulence of very virulent infectious bursal disease virus (vvIBDV) in SPF chickens and increases replication in CEF cells. Virology. 2013;440:204-9 pubmed publisher
    b>Infectious bursal disease virus (IBDV) is a birnavirus that causes immunosuppressive disease in chickens. The emergence of very virulent IBDV (vvIBDV) has brought new challenges for this disease...
  21. Saugar I, Irigoyen N, Luque D, Carrascosa J, Rodr guez J, Cast n J. Electrostatic interactions between capsid and scaffolding proteins mediate the structural polymorphism of a double-stranded RNA virus. J Biol Chem. 2010;285:3643-50 pubmed publisher
    ..basis of the flexibility mechanism of VP2, the capsid protein of the double-stranded RNA virus infectious bursal disease virus. The initial assembly, a procapsid-like structure, is built by the protein precursor pVP2 and ..
  22. Aizenshtein E, Yosipovich R, Kvint M, Shadmon R, Krispel S, Shuster E, et al. Practical aspects in the use of passive immunization as an alternative to attenuated viral vaccines. Vaccine. 2016;34:2513-8 pubmed publisher
    ..Following injection of 1-day-old broilers with antibodies against infectious bursal disease virus, protective antibody levels were acquired for the entire period of sensitivity to this pathogen (35 ..
  23. Song B, Li X, Ma J, Yu L, Feng Z, Liu Z, et al. Prokaryotic Expression and Anti-IBDV Activity of Chicken Interleukin-18 and Interferon-γ. Cytogenet Genome Res. 2017;153: pubmed publisher
    ..After 24 h, one 50% tissue culture infective dose (TCID50) of infectious bursal disease virus (IBDV) was inoculated into the chicken embryonic fibroblast cells...
  24. Fu M, Wang B, Chen X, He Z, Wang Y, Li X, et al. MicroRNA gga-miR-130b Suppresses Infectious Bursal Disease Virus Replication via Targeting of the Viral Genome and Cellular Suppressors of Cytokine Signaling 5. J Virol. 2018;92: pubmed publisher
    ..However, the role of miRNAs in the host response against infectious bursal disease virus (IBDV) infection is not clear...
  25. Jeon W, Lee H, Roh I, Yoon Y, Kim J, Choi K. Effect of maternally derived antibody on sequential infection with highly virulent bursal disease virus in newly hatched broilers. Poult Sci. 2017;: pubmed publisher
    Maternally derived antibodies (MDAs) are important for protection against very virulent infectious bursal disease virus (vvIBDV)...
  26. Felice V, Franzò G, Catelli E, Di Francesco A, Bonci M, Cecchinato M, et al. Genome sequence analysis of a distinctive Italian infectious bursal disease virus. Poult Sci. 2017;: pubmed publisher
    In a recent study, an emerging infectious bursal disease virus (IBDV) genotype (ITA) was detected in IBDV-live vaccinated broilers without clinical signs of infectious bursal disease (IBD)...
  27. Kurukulasuriya S, Ahmed K, Ojkic D, Gunawardana T, Goonewardene K, Gupta A, et al. Modified live infectious bursal disease virus (IBDV) vaccine delays infection of neonatal broiler chickens with variant IBDV compared to turkey herpesvirus (HVT)-IBDV vectored vaccine. Vaccine. 2017;35:882-888 pubmed publisher
    ..Early age infection with infectious bursal disease virus (IBDV) results in long-lasting immunosuppression and profound economic losses...
  28. Richetta M, Gómez E, Lucero M, Chimeno Zoth S, Gravisaco M, Calamante G, et al. Comparison of homologous and heterologous prime-boost immunizations combining MVA-vectored and plant-derived VP2 as a strategy against IBDV. Vaccine. 2017;35:142-148 pubmed publisher
    Different immunogens such as subunit, DNA or live viral-vectored vaccines against Infectious Bursal Disease virus (IBDV) have been evaluated in the last years...
  29. Lawal N, Hair Bejo M, Arshad S, Omar A, Ideris A. Adaptation and Molecular Characterization of Two Malaysian Very Virulent Infectious Bursal Disease Virus Isolates Adapted in BGM-70 Cell Line. Adv Virol. 2017;2017:8359047 pubmed publisher
    Two Malaysian very virulent infectious bursal disease virus (vvIBDV) strains UPM0081 and UPM190 (also known as UPMB00/81 and UPM04/190, respectively) isolated from local IBD outbreaks were serially passaged 12 times (EP12) in specific ..
  30. Giotis E, Ross C, Robey R, Nohturfft A, Goodbourn S, Skinner M. Constitutively elevated levels of SOCS1 suppress innate responses in DF-1 immortalised chicken fibroblast cells. Sci Rep. 2017;7:17485 pubmed publisher
    ..under both normal and stimulated conditions using chicken interferon-α (chIFN-α) and the attenuated infectious bursal disease virus vaccine strain PBG98. We found that DF-1 have an attenuated innate response compared to CEFs...