Gumboro virus

Summary

Alias: Infectious bursal disease virus, Avian infectious bursal disease virus, Infectious bursal disease virus of chickens, infectious bursal disease virus IBDV, IBDV

Top Publications

  1. ncbi Flow cytometric analysis of the neutralizing immune response against infectious bursal disease virus using reticuloendotheliosis virus-transformed lymphoblastoid cell lines
    S K Reddy
    Departement de Pathologie et Microbiologie, Faculte de Medecine Veterinaire, Universite de Montreal, St Hyacinthe, Quebec, Canada
    J Virol Methods 44:167-77. 1993
  2. ncbi Structure of birnavirus-like particles determined by combined electron cryomicroscopy and X-ray crystallography
    Joan Pous
    Laboratoire de Virologie Moleculaire et Structurale, UMR 2472 CNRS INRA, 1 Avenue de la Terrasse, F 91198 Gif sur Yvette, France
    J Gen Virol 86:2339-46. 2005
  3. pmc Autoproteolytic activity derived from the infectious bursal disease virus capsid protein
    Nerea Irigoyen
    Department of Molecular and Cellular Biology, Centro Nacional de Biotecnologia Consejo Superior de Investigaciones Cientificas CSIC, Cantoblanco, 28049 Madrid, Spain
    J Biol Chem 284:8064-72. 2009
  4. doi Influence of chicken serum mannose-binding lectin levels on the immune response towards Escherichia coli
    L R Norup
    Department of Animal Health, Welfare and Nutrition, Faculty of Agricultural Sciences, University of Aarhus, PO Box 50, DK 8830 Tjele, Denmark
    Poult Sci 88:543-53. 2009
  5. ncbi Health evaluation of free-ranging and captive blue-fronted Amazon parrots (Amazona aestiva) in the Gran chaco, Bolivia
    Sharon L Deem
    Field Veterinary Program, Wildlife Conservation Society, 2300 Southern Boulevard, Bronx, New York 10460, USA
    J Zoo Wildl Med 36:598-605. 2005
  6. ncbi [Establishment and biological properties of hybridoma cell lines secreting anti-IBDV idiotypic antibodies]
    Rui Liang Zhu
    Animal Science and Veterinary College, Yangzhou University, Yangzhou 225009, China
    Sheng Wu Gong Cheng Xue Bao 19:462-6. 2003
  7. ncbi Pigeon paramyxovirus: association with common avian pathogens in chickens and serologic survey in wild birds
    H Toro
    Department of Pathobiology, College of Veterinary Medicine, 166 Greene Hall, Auburn University, AL 36849 5519, USA
    Avian Dis 49:92-8. 2005
  8. ncbi Differential detection of turkey coronavirus, infectious bronchitis virus, and bovine coronavirus by a multiplex polymerase chain reaction
    C C Loa
    Department of Veterinary Pathobiology and Animal Disease Diagnostic Laboratory, Purdue University, West Lafayette, IN 47907 2065, USA
    J Virol Methods 131:86-91. 2006
  9. doi Sequence variability and evolution of the terminal overlapping VP5 gene of the infectious bursal disease virus
    Martín Hernández
    Seccion Genetica Evolutiva, Facultad de Ciencias, Departamento de Biologia Animal, Instituto de Biologia, Universidad de la Republica, Iguá 4225 Esq Mataojo, C P 11400, Montevideo, Uruguay
    Virus Genes 41:59-66. 2010
  10. ncbi Field trial in commercial broilers with a multivalent in ovo vaccine comprising a mixture of live viral vaccines against Marek's disease, infectious bursal disease, Newcastle disease, and fowl pox
    J M Sharma
    Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul 55108, USA
    Avian Dis 46:613-22. 2002

Research Grants

  1. Edward H Egelman; Fiscal Year: 2016
  2. HIGH SPEED HIGH RESOLUTION PHASE RESOLVED OCT/ODT
    Zhongping Chen; Fiscal Year: 2001
  3. Optical Biopsy Using MEMs Technology
    Zhongping Chen; Fiscal Year: 2006
  4. Fourier Domain Functional OCT
    Zhongping Chen; Fiscal Year: 2009

Patents

  1. COMPOSITIONS AND METHODS RELATED TO VIRAL VACCINES
  2. An infectious bursal disease virus mutant and vaccines
  3. Attenuated very virulent infectious bursal disease virus
  4. Serotype chimeric ibdv strains
  5. Mosaic infectious bursal disease virus vaccines
  6. Mosaic infectious bursal disease virus vaccines
  7. Genetically engineered cell culture adapted infectious bursal diseases virus (ibdv) mutants
  8. Preparation of Vaccine Master Cell Lines Using Recombinant Plant Suspension Cultures
  9. Avian Herpesvirus-based Recombinant Infectious Bursal Disease
  10. Stable Immunoprophylactic and Therapeutic Compositions Derived From Transgenic Plant Cells and Methods for Production

Detail Information

Publications246 found, 100 shown here

  1. ncbi Flow cytometric analysis of the neutralizing immune response against infectious bursal disease virus using reticuloendotheliosis virus-transformed lymphoblastoid cell lines
    S K Reddy
    Departement de Pathologie et Microbiologie, Faculte de Medecine Veterinaire, Universite de Montreal, St Hyacinthe, Quebec, Canada
    J Virol Methods 44:167-77. 1993
    b>Infectious bursal disease virus (IBDV) is a lymphotropic virus with cytocidal effect on B lymphocytes of the bursa of Fabricius...
  2. ncbi Structure of birnavirus-like particles determined by combined electron cryomicroscopy and X-ray crystallography
    Joan Pous
    Laboratoire de Virologie Moleculaire et Structurale, UMR 2472 CNRS INRA, 1 Avenue de la Terrasse, F 91198 Gif sur Yvette, France
    J Gen Virol 86:2339-46. 2005
    ..Using freeze-drying and heavy metal shadowing, the capsids of two birnaviruses, infectious bursal disease virus (IBDV) and infectious pancreatic necrosis virus, as well as of an IBDV virus-like particle (VLP) are ..
  3. pmc Autoproteolytic activity derived from the infectious bursal disease virus capsid protein
    Nerea Irigoyen
    Department of Molecular and Cellular Biology, Centro Nacional de Biotecnologia Consejo Superior de Investigaciones Cientificas CSIC, Cantoblanco, 28049 Madrid, Spain
    J Biol Chem 284:8064-72. 2009
    ..Here we show that the precursor (pVP2) of the capsid protein VP2 of the infectious bursal disease virus (IBDV), an avian double-stranded RNA virus, has autoproteolytic activity...
  4. doi Influence of chicken serum mannose-binding lectin levels on the immune response towards Escherichia coli
    L R Norup
    Department of Animal Health, Welfare and Nutrition, Faculty of Agricultural Sciences, University of Aarhus, PO Box 50, DK 8830 Tjele, Denmark
    Poult Sci 88:543-53. 2009
    ..after attempts were made to immunosuppress the chickens by immunization with a live attenuated infectious bursal disease virus (IBDV) vaccine strain...
  5. ncbi Health evaluation of free-ranging and captive blue-fronted Amazon parrots (Amazona aestiva) in the Gran chaco, Bolivia
    Sharon L Deem
    Field Veterinary Program, Wildlife Conservation Society, 2300 Southern Boulevard, Bronx, New York 10460, USA
    J Zoo Wildl Med 36:598-605. 2005
    ..to have antibodies to avian influenza virus, Chlamydophila psittaci, infectious bronchitis virus, infectious bursal disease virus, infectious laryngotracheitis virus, Marek's disease virus, paramyxovirus-1, paramyxovirus-2, ..
  6. ncbi [Establishment and biological properties of hybridoma cell lines secreting anti-IBDV idiotypic antibodies]
    Rui Liang Zhu
    Animal Science and Veterinary College, Yangzhou University, Yangzhou 225009, China
    Sheng Wu Gong Cheng Xue Bao 19:462-6. 2003
    ..disease (IBD) have become more and more difficult due to the emergence of very virulent strains of infectious bursal disease virus (vvIBDV) and the variant strains of IBDV...
  7. ncbi Pigeon paramyxovirus: association with common avian pathogens in chickens and serologic survey in wild birds
    H Toro
    Department of Pathobiology, College of Veterinary Medicine, 166 Greene Hall, Auburn University, AL 36849 5519, USA
    Avian Dis 49:92-8. 2005
    ..from pigeons from east-central Alabama and used in association with chicken anemia virus (CAV), infectious bursal disease virus (IBDV), or finch Mycoplasma gallisepticum (MG) in specific-pathogen-free chickens to assess dinical ..
  8. ncbi Differential detection of turkey coronavirus, infectious bronchitis virus, and bovine coronavirus by a multiplex polymerase chain reaction
    C C Loa
    Department of Veterinary Pathobiology and Animal Disease Diagnostic Laboratory, Purdue University, West Lafayette, IN 47907 2065, USA
    J Virol Methods 131:86-91. 2006
    ..disease virus, Marek's disease virus, turkey pox virus, pigeon pox virus, fowl pox virus, reovirus, infectious bursal disease virus, enterovirus, astrovirus, Salmonella enterica, Escherichia coli, and Mycoplasma gallisepticum...
  9. doi Sequence variability and evolution of the terminal overlapping VP5 gene of the infectious bursal disease virus
    Martín Hernández
    Seccion Genetica Evolutiva, Facultad de Ciencias, Departamento de Biologia Animal, Instituto de Biologia, Universidad de la Republica, Iguá 4225 Esq Mataojo, C P 11400, Montevideo, Uruguay
    Virus Genes 41:59-66. 2010
    The infectious bursal disease virus (IBDV; Birnaviridae family) constitutes one of the main threats to the poultry industry worldwide...
  10. ncbi Field trial in commercial broilers with a multivalent in ovo vaccine comprising a mixture of live viral vaccines against Marek's disease, infectious bursal disease, Newcastle disease, and fowl pox
    J M Sharma
    Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul 55108, USA
    Avian Dis 46:613-22. 2002
    ..live viruses including serotypes 1, 2, and 3 of Marek's disease virus (MDV), an intermediate infectious bursal disease virus (IBDV) and a recombinant fowl poxvirus (FPV) vector vaccine containing HN and F genes of Newcastle ..
  11. ncbi Birnavirus VP1 proteins form a distinct subgroup of RNA-dependent RNA polymerases lacking a GDD motif
    Philip S Shwed
    Department of Microbiology, University of Guelph, Guelph, Ontario, Canada
    Virology 296:241-50. 2002
    ..in the family Birnaviridae, namely, infectious pancreatic necrosis virus (genus Aquabirnavirus) and infectious bursal disease virus (genus Avibirnavirus), the DXV (genus Entomobirnavirus) VP1 protein contains a consensus GTP-binding ..
  12. ncbi Backyard chicken flocks pose a disease risk for neotropic birds in Costa Rica
    Sonia M Hernandez-Divers
    Odum School of Ecology, University of Georgia, Athens, GA 30602, USA
    Avian Dis 52:558-66. 2008
    ..virus, infectious laryngotracheitis virus, infectious bronchitis virus, chicken anemia virus, and infectious bursal disease virus, as well as both Mycoplasma gallisepticum and Mycoplasma synoviae, appear to be significant diseases ..
  13. ncbi Infectious bursal disease virus of chickens: pathogenesis and immunosuppression
    J M Sharma
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul, MN 55108, USA
    Dev Comp Immunol 24:223-35. 2000
    b>Infectious bursal disease virus (IBDV) is an important immunosuppressive virus of chickens. The virus is ubiquitous and, under natural conditions, chickens acquire infection by the oral route. IgM+ cells serve as targets for the virus...
  14. ncbi Infectious bronchitis virus in the chicken Harderian gland and lachrymal fluid: viral load, infectivity, immune cell responses, and effects of viral immunodeficiency
    F W van Ginkel
    Auburn University College of Veterinary Medicine, 166 Greene Hall, Auburn, AL 36849, USA
    Avian Dis 52:608-17. 2008
    ..tonsils of immunocompetent chickens and chickens infected with chicken anemia virus (CAV) and/or infectious bursal disease virus (IBDV)...
  15. doi Adjuvant activity of chicken interleukin-12 co-administered with infectious bursal disease virus recombinant VP2 antigen in chickens
    Bor Sheu Su
    Department of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, 250 Kuo Kuang Road, Taichung 402, Taiwan
    Vet Immunol Immunopathol 139:167-75. 2011
    A recombinant fowlpox virus (rFPV/VP2) expressing infectious bursal diseases virus (IBDV) VP2 gene has been constructed...
  16. doi Impaired intestinal mucosal immunity in specific-pathogen-free chickens after infection with very virulent infectious bursal disease virus
    D Wang
    College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China
    Poult Sci 88:1623-8. 2009
    ..However, the kinetics of the intestinal mucosal immune parameters in infectious bursal disease virus (IBDV)-infected birds remains unclear...
  17. pmc Infectious bursal disease virus capsid protein VP3 interacts both with VP1, the RNA-dependent RNA polymerase, and with viral double-stranded RNA
    Mirriam G J Tacken
    Division of Infectious Diseases and Food Chain Quality, Institute for Animal Science and Health ID Lelystad B V, NL 8200 AB Lelystad, The Netherlands
    J Virol 76:11301-11. 2002
    b>Infectious bursal disease virus (IBDV) is a double-stranded RNA (dsRNA) virus of the Birnaviridae family...
  18. ncbi Impact of heterophil granulocyte depletion caused by 5-fluorouracil on infectious bursal disease virus infection in specific pathogen free chickens
    Susanne Kabell
    Danish Institute for Food and Veterinary Research, Hangøvej 2, DK 8200 Aarhus N, Denmark
    Avian Pathol 35:341-8. 2006
    ..of heterophil granulocytes, on clinical symptoms and histological lesions during the progress of infectious bursal disease virus (IBDV) infection in chickens...
  19. doi Development, standardization and assessment of PCR systems for purity testing of avian viral vaccines
    Hans Peter Ottiger
    Institute of Virology and Immunoprophylaxis IVI, OMCL Vaccine Control, Swiss Federal Veterinary Office, CH 3147 Mittelhäusern, Switzerland
    Biologicals 38:381-8. 2010
    ..chain reaction (PCR) assays for the detection of avian leucosis virus, avian orthoreovirus, infectious bursal disease virus, infectious bronchitis virus, Newcastle disease virus, infectious laryngotracheitis virus, influenza ..
  20. doi Comparative susceptibility of chickens, turkeys and ducks to infectious bursal disease virus using immunohistochemistry
    O A Oladele
    Department of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria
    Vet Res Commun 33:111-21. 2009
    ..Presence of IBD viral antigen in organs of all 3 poultry species is indicative of infections. The innate ability of turkeys and ducks to prevent appreciable replication of IBD virus after infection requires further investigation...
  21. ncbi Sequence analysis of the bicistronic Drosophila X virus genome segment A and its encoded polypeptides
    H K Chung
    Department of Microbiology, College of Biological Sciences, University of Guelph, Ontario, Canada
    Virology 225:359-68. 1996
    ..specified by the two ORFs were compared to those of infectious pancreatic necrosis virus (IPNV) and infectious bursal disease virus (IBDV) that represent the two other genera (aquabirnavirus and avibirnavirus) of the Birnaviridae ..
  22. ncbi Genotyping of Canadian field strains of infectious bursal disease virus
    Davor Ojkic
    Animal Health Laboratory, University of Guelph, Ontario, Guelph, Canada
    Avian Pathol 36:427-33. 2007
    For this retrospective study, infectious bursal disease virus (IBDV) was detected in 134 bursal samples that originated from flocks with conditions such as airsacculitis, tracheitis, pneumonia, septicaemia, inclusion body hepatitis, ..
  23. ncbi Changes in VP3 and VP5 genes during the attenuation of the very virulent infectious bursal disease virus strain Gx isolated in China
    Xiaomei Wang
    National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute of the Chinese Academy of Agricultural Sciences, 427 Maduan Street, Harbin, 150001, PR China
    Virus Genes 34:67-73. 2007
    A very virulent infectious bursal disease virus (vvIBDV) Gx strain with high pathogenicity was attenuated through replication in specific-pathogen free (SPF) chicken embryos and in chicken embryo fibroblast (CEF) cell cultures...
  24. ncbi Effects of chicken anemia virus and infectious bursal disease virus in commercial chickens
    H Toro
    Department of Pathobiology, College of Veterinary Medicine, 264 Greene Hall, Auburn University, AL 36849 5519, USA
    Avian Dis 53:94-102. 2009
    The effects of chicken anemia virus (CAV) and infectious bursal disease virus (IBDV) coinfection in commercial layer-type and meat-type (broiler) chickens with specific maternal immunity were evaluated...
  25. doi Infectious Bursal disease virus: ribonucleoprotein complexes of a double-stranded RNA virus
    Daniel Luque
    Department of Structure of Macromolecules, Centro Nacional de Biotecnologia CSIC, C Darwin No 3, Cantoblanco, E 28049 Madrid, Spain
    J Mol Biol 386:891-901. 2009
    ..We used electron microscopy and functional analysis to characterize these RNP complexes of infectious bursal disease virus, the best characterized member of the Birnaviridae family...
  26. ncbi Protection against infectious bursal disease virulent challenge conferred by a recombinant avian adeno-associated virus vaccine
    F Perozo
    Poultry Diagnostic and Research Center, University of Georgia, Athens, GA 30602, USA
    Avian Dis 52:315-9. 2008
    ..In this experiment, an avian adeno-associated virus (AAAV) expressing the infectious bursal disease virus (IBDV) VP2 protein (rAAAV-VP2) was evaluated for protection against IBDV-virulent challenge...
  27. ncbi In vitro evaluation of the antiviral activity of extracts from the lichen Parmelia perlata (L.) Ach. against three RNA viruses
    Charles O Esimone
    Division of Pharmaceutical Microbiology, Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Nigeria
    J Infect Dev Ctries 1:315-20. 2007
    ..Due to the high abundance of Parmelia perlata in the Eastern parts of Nigeria, we decided to explore whether it possesses antiviral activity against some common animal and human viruses...
  28. ncbi [Cloning of infectious bursal disease virus (Gt strain) lack of VP5 gene]
    Liting Qin
    Division of Avian Infectious Diseases, National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150001, China
    Wei Sheng Wu Xue Bao 48:1666-70. 2008
    b>Infectious bursal disease virus (IBDV) belongs to genus Avibirnavirus of the family Birnaviridae...
  29. ncbi Infectious bursal disease virus recovery from Vero cells transfected with RNA transcripts is enhanced by expression of the structural proteins in trans
    M A Peters
    Department of Veterinary Pathobiology, Purdue University, West Lafayette, Indiana 47907, USA
    Arch Virol 150:2183-94. 2005
    ..3) pfu/ml to 10(10.3) pfu/ml with expression of the viral polyprotein. This report is the first to describe a reverse genetics model for IBD virus with high efficiency of virus recovery for non-culture adapted strains...
  30. ncbi Cloned Vero cell lines transfected with full-length A-segment or ORF1 cDNA sequence of IBDV
    Juxiu Ye
    Laboratory of Virology and Immunology, Institute of Preventive Veterinary Medicine, College of Animal Sciences, Zhejiang University, 268 Kaixuan Road, Hangzhou, Zhejiang 310029, PR China
    Cell Biol Int 31:165-72. 2007
    Recombinant plasmids containing the A-segment or VP2/4/3 gene of infectious bursal disease virus (IBDV) were transfected into Vero cells. Monoclonal Vero cell lines were generated under G418 selection...
  31. ncbi Analyses of the results of different test systems in the 2005 global proficiency testing schemes for infectious bursal disease virus and Newcastle disease virus antibody detection in chicken serum
    J J de Wit
    GD, Animal Health Service Ltd AA Deventer, The Netherlands
    Avian Pathol 36:177-83. 2007
    ..of global proficiency testing schemes (PTS) for serological tests to detect antibodies against infectious bursal disease virus (IBDV) and Newcastle disease virus (NDV) in chicken serum, in which 125 and 120 laboratories, ..
  32. pmc Complete, long-lasting protection against lethal infectious bursal disease virus challenge by a single vaccination with an avian herpesvirus vector expressing VP2 antigens
    K Tsukamoto
    Department of Infectious Diseases, National Institute of Animal Health, Tsukuba, Ibaraki 305 0856, Japan
    J Virol 76:5637-45. 2002
    ..In this study, two herpesvirus of turkey recombinants (rHVTs) expressing large amounts of infectious bursal disease virus (IBDV) VP2 antigen under the control of a human cytomegalovirus (CMV) promoter or CMV/beta-actin ..
  33. ncbi Development of differential RT-PCR assays and molecular characterization of the complete VP1 gene of five strains of very virulent infectious bursal disease virus
    S Ashraf
    Food Animal Health Research Program, Ohio Agricultural Research and Development Center, The Ohio State University, 1680 Madison Avenue, Wooster, OH 44691, USA
    Avian Dis 51:935-41. 2007
    Several antigenic and pathogenic subtypes of infectious bursal disease virus (IBDV) have been identified worldwide...
  34. ncbi [Recombinant Vp2 protein of infectious bursal disease virus AH1 strain expressed in insect cells: a vaccine candidate]
    Wei Ouyang
    Key Laboratory of Animal Diseases and Immunology, Ministry of Agriculture National Center for Engineering Research of Veterinary Bio products, Institute of Veterinary Medicine, Jiangsu Academy of Sciences, Nanjing 210014, China
    Sheng Wu Gong Cheng Xue Bao 26:595-603. 2010
    ..of the available IBD vaccine is insufficient to fully protect against the prevailing strain of the infectious bursal disease virus (IBDV)...
  35. ncbi Aflatoxicosis, infectious bursal disease and immune response to Newcastle disease vaccination in rural chickens
    Maxwell O Otim
    Livestock Health Research Institute, LIRI, P O Box 96, Tororo, Uganda
    Avian Pathol 34:319-23. 2005
    To investigate the immunosuppressive effects of infectious bursal disease virus (IBDV) and aflatoxin in indigenous chickens of Uganda, Newcastle disease (ND) seronegative chicks were randomly allocated to two treatment groups...
  36. pmc Molecular and structural bases for the antigenicity of VP2 of infectious bursal disease virus
    Tobias Letzel
    Institute of Molecular Biology, Federal Research Institute for Animal Health, Boddenblick 5a, 17493 Greifswald Insel Riems, Germany
    J Virol 81:12827-35. 2007
    b>Infectious bursal disease virus (IBDV), a member of the family Birnaviridae, is responsible for a highly contagious and economically important disease causing immunosuppression in chickens...
  37. ncbi Humoral and cell-mediated immunopotentiation in vaccinated chicken layers by thymic hormones and zinc
    E K Barbour
    Animal Science Department, Faculty of Agricultural and Food Sciences, American University of Beirut, New York, NY 10022, USA
    Vaccine 16:1650-5. 1998
    ..layers at 29 and 31 weeks of age, and containing antigens of infectious bronchitis virus (IBV), infectious bursal disease virus (IBDV), and Newcastle disease virus (NDV), were quantitated in five vaccinated and one unvaccinated-..
  38. ncbi Major histocompatibility complex-linked immune response of young chickens vaccinated with an attenuated live infectious bursal disease virus vaccine followed by an infection
    H R Juul-Madsen
    Danish Institute of Agricultural Sciences, Tjele
    Poult Sci 81:649-56. 2002
    The influence of the MHC on infectious bursal disease virus (IBDV) vaccine response in chickens was investigated in three different chicken lines containing four different MHC haplotypes...
  39. doi The potent adjuvant effects of chicken beta-defensin-1 when genetically fused with infectious bursal disease virus VP2 gene
    Hui Hua Zhang
    Department of Animal Science, College of Life Sciences, Foshan University, Xian xi Lake, Nan hai Da li District, Foshan 528231, Guan dong, PR China
    Vet Immunol Immunopathol 136:92-7. 2010
    ..beta-defensin-1 (also named avian beta-defensin-1, AvBD1) has the potent adjuvant effects on DNA vaccine encoding IBDV VP2 gene, when genetically fused with VP2 gene. The recombinant vectors pcDNA3.1(+)-VP2 and pcDNA3...
  40. ncbi Interactions in vivo between the proteins of infectious bursal disease virus: capsid protein VP3 interacts with the RNA-dependent RNA polymerase, VP1
    M G Tacken
    Institute for Animal Science and Health ID Lelystad, Department of Avian Virology, PO Box 65, NL 8200 AB Lelystad, The Netherlands
    J Gen Virol 81:209-18. 2000
    Little is known about the intermolecular interactions between the viral proteins of infectious bursal disease virus (IBDV)...
  41. doi DNA-mediated vaccination conferring protection against infectious bursal disease in broiler chickens in the presence of maternal antibody
    Ming Kun Hsieh
    Department of Comparative Pathobiology, School of Veterinary Medicine, Purdue University, 406 South University Street, West Lafayette, IN 47907 2065, USA
    Vaccine 28:3936-43. 2010
    The objective of the present study was to determine if a DNA vaccine carrying large segment gene of infectious bursal disease virus (IBDV) could confer protection against infectious bursal disease (IBD) in broiler chickens in the ..
  42. ncbi Bilateral effects of vaccination against infectious bursal disease and Newcastle disease in specific-pathogen-free layers and commercial broiler chickens
    Silke Rautenschlein
    Clinic for Poultry, University of Veterinary Medicine Hannover, Büinteweg 17, 30559 Hannover, Germany
    Avian Dis 51:14-20. 2007
    Different infectious bursal disease virus (IBDV) live vaccines (intermediate, intermediate plus) were compared for their immunosuppressive abilities in specific-pathogen-free (SPF) layer-type chickens or commercial broilers...
  43. ncbi Effects of two infectious bursal disease vaccine virus strains on hepatic microsomal enzyme activities in chickens
    Andreja Prevendar Crnić
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Zagreb, Heinzelova 55, 10000 Zagreb, Croatia
    Acta Vet Hung 54:281-93. 2006
    ..As expected, the antibody titres against infectious bursal disease virus in the serum were increased in both tested groups in relation to each administered vaccine...
  44. doi Turkey coronavirus non-structure protein NSP15--an endoribonuclease
    Jianzhong Cao
    Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, USA
    Intervirology 51:342-51. 2008
    ..TCoV nsp15 consists of 338 residues and shares 40% sequence similarity to U-specific Nidovirales endoribonuclease (NendoU) of severe acute respiratory syndrome coronavirus...
  45. ncbi Hematology, serum chemistry, and serology of Galápagos penguins (Spheniscus mendiculus) in the Galápagos Islands, Ecuador
    Erika K Travis
    Saint Louis Zoo, One Government Drive, Saint Louis, Missouri 63110, USA
    J Wildl Dis 42:625-32. 2006
    ..Birds were seronegative to avian paramyxovirus type 1-3, avian influenza virus, infectious bursal disease virus, Marek's disease virus (herpes), reovirus, avian encephalomyelitis virus, and avian adenovirus type 1 ..
  46. ncbi Preliminary studies of primary ostrich fibroblasts for the isolation of ratite viruses
    S J Rodgers
    Oklahoma Animal Disease Diagnostic Laboratory, College of Veterinary Medicine, Oklahoma State University, Stillwater 74076 7001
    Avian Dis 38:866-72. 1994
    ..propagate stock avian viruses of infectious bronchitis virus, paramyxiovirus-1 (PMV-1), PMV-2, PMV-3, infectious bursal disease virus, quail bronchitis virus, avian reovirus, turkey coronavirus, and two ostrich-originating specimens (..
  47. doi Infectious bursal disease virus persistently infects bursal B-lymphoid DT40 cells
    Laura Delgui
    Departamento de Biologia Molecular y Celular, Centro Nacional de Biotecnologia, Darwin 3, 28049 Madrid, Spain
    J Gen Virol 90:1148-52. 2009
    b>Infectious bursal disease virus (IBDV), an important avian pathogen, exhibits a specific tropism for immature B-lymphocyte populations...
  48. doi Effective protection by high efficiency bicistronic DNA vaccine against infectious bursal disease virus expressing VP2 protein and chicken IL-2
    Sachin Kumar
    Virginia Maryland Regional College of Veterinary Medicine, College Park, MD 20742, USA
    Vaccine 27:864-9. 2009
    Infectious bursal disease (IBD) is an acute and contagious viral infection of young chickens caused by IBD virus (IBDV). IBDV belongs to genus Avibirnavirus of family Birnaviridae...
  49. pmc Infectious bursal disease virus capsid assembly and maturation by structural rearrangements of a transient molecular switch
    Daniel Luque
    Departamento de Estructura de Macromoléculas, Centro Nacional de Biotecnologia CSIC, C Darwin No 3, Cantoblanco, E 28049 Madrid, Spain
    J Virol 81:6869-78. 2007
    b>Infectious bursal disease virus (IBDV), a double-stranded RNA (dsRNA) virus belonging to the Birnaviridae family, is an economically important avian pathogen...
  50. ncbi Adaptation of a mallard H5N2 low pathogenicity influenza virus in chickens with prior history of infection with infectious bursal disease virus
    Gloria Ramirez-Nieto
    Department of Veterinary Medicine, University of Maryland, College Park 20742 3711, USA
    Avian Dis 54:513-21. 2010
    ..had been previously infected at 2 days of age with, and recovered from, the immunosuppressive agent infectious bursal disease virus (IBDV; herein referred to as IBDV chickens)...
  51. ncbi Pivotal role of ChIFNgamma in the pathogenesis and immunosuppression of infectious bursal disease
    Fabienne Rauw
    Avian Virology and Immunology Unit, Veterinary and Agrochemical Research Centre, Ukkel Brussels, Belgium
    Avian Pathol 36:367-74. 2007
    ..pivotal role of chicken interferon-gamma (ChIFNgamma) in the pathogenesis and immunosuppression of infectious bursal disease virus (IBDV) infection and is divided into in vivo, ex vivo and in vitro experiments...
  52. doi Detection and characterization of infectious bursal disease viruses in broilers at processing
    Daral J Jackwood
    Food Animal Health Research Program, Ohio Agricultural Research and Development Center, The Ohio State University, 1680 Madison Avenue, Wooster, OH 44691, USA
    Prev Vet Med 97:45-50. 2010
    The presence of infectious bursal disease virus (IBDV) in broilers entering processing plants was examined...
  53. doi Biological properties of a naturally attenuated infectious bursal disease virus isolated from a backyard chicken flock
    Maja Velhner
    Scientific Veterinary Institute Novi Sad, Rumenacki put 20, Novi Sad, Serbia
    Acta Vet Hung 58:499-509. 2010
    ..None of the commercial vaccine viruses has a similar arrangement of amino acids in the variable domain of IBDV. This strongly suggests that IBDVtc originates from a very virulent strain...
  54. ncbi Early stages of infectious bursal disease virus infection in chickens detected by in situ reverse transcriptase-polymerase chain reaction
    M F Zhang
    Laboratory of Animal Molecular Virology, Department of Biochemistry and Molecular Biology, College of Biological Science, China Agricultural University, Beijing 100094, China
    Avian Pathol 31:593-7. 2002
    Two infectious bursal disease virus (IBDV) strains were inoculated both intranasally and by eye drop into 5-week-old specific pathogen free chickens...
  55. ncbi [Expression and immunogenic analysis for the tandem-arranged multiple mimic epitope gene of infectious bursal disease virus]
    Yong shan Wang
    Military Medical Institute of Nanjing Command, Center for Disease Control and Prevention of Nanjing Command, Nanjing 210002, China
    Wei Sheng Wu Xue Bao 47:121-5. 2007
    Five mimic epitopes of Infectious bursal disease virus (IBDV) have been identified from a 12-mer phage-displayed peptide library by 5 monoclonal antibodies...
  56. ncbi Role of intrabursal T cells in infectious bursal disease virus (IBDV) infection: T cells promote viral clearance but delay follicular recovery
    S Rautenschlein
    Department of Veterinary Pathobiology, University of Minnesota, St Paul, Minnesota, USA
    Arch Virol 147:285-304. 2002
    b>Infectious bursal disease virus (IBDV) induces an acute, highly contagious immunosuppressive disease in young chickens. We examined the role of T cells in IBDV-induced immunopathogenesis and tissue recovery...
  57. doi Role of chicken melanoma differentiation-associated gene 5 in induction and activation of innate and adaptive immune responses to infectious bursal disease virus in cultured macrophages
    Chih Chun Lee
    Department of Comparative Pathobiology, Purdue University, 406, S University St, West Lafayette, IN, 47907, USA
    Arch Virol 160:3021-35. 2015
    ..present study was to determine if chicken melanoma-differentiation-associated gene 5 (MDA5) senses infectious bursal disease virus infection to induce innate immunity that bridges to adaptive immunity...
  58. pmc Effects of DDA, CpG-ODN, and plasmid-encoded chicken IFN-gamma on protective immunity by a DNA vaccine against IBDV in chickens
    Ha Jung Roh
    School of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon 200 701, Korea
    J Vet Sci 7:361-8. 2006
    ..CpG-ODN), and chicken interferon-gamma (ChIFN-gamma) on a DNA vaccine (pcDNA-VP243) against the infectious bursal disease virus (IBDV). A plasmid encoding chicken IFN-ã was constructed...
  59. pmc Structural peptides of a nonenveloped virus are involved in assembly and membrane translocation
    Christophe Chevalier
    Unité de Recherche de Virologie et Immunologie Moléculaires, INRA, F 78350 Jouy en Josas, France
    J Virol 79:12253-63. 2005
    The capsid of infectious bursal disease virus (IBDV), a nonenveloped virus of the family Birnaviridae, has a T=13l icosahedral shell constituted by a single protein, VP2, and several disordered peptides, all derived from the precursor ..
  60. doi Mortality of one-week-old chickens during naturally occurring Marek's disease virus infection
    F R Carvallo
    Connecticut Veterinary Medical Diagnostic Laboratory, Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, CT 06269, USA
    Vet Pathol 48:993-8. 2011
    ..PCR yielded an amplicon with 97% homology to the meq gene of MDV. No evidence of co-infection by either of the immunosuppressive agents chicken anemia virus and infectious bursal disease virus was detected.
  61. doi Role of naturally occurring genome segment reassortment in the pathogenicity of IBDV field isolates in Three-Yellow chickens
    Xiumiao He
    a School of Marine Sciences and Biotechnology Guangxi Colleges and Universities Key Laboratory of Utilization of Microbial and Botanical Resources, Guangxi University for Nationalities, Nanning, Guangxi, People s Republic of China
    Avian Pathol 45:178-86. 2016
    Reassortment among genome segments of infectious bursal disease virus (IBDV) field isolates was reported frequently worldwide, however the pathogenicity of the reassortant field IBDV is poorly understood...
  62. pmc Pigeon RIG-I Function in Innate Immunity against H9N2 IAV and IBDV
    Wenping Xu
    State Key Laboratory for Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing 100193, China
    Viruses 7:4131-51. 2015
    ..receptor (PRR), can sense various RNA viruses, including the avian influenza virus (AIV) and infectious bursal disease virus (IBDV), and trigger the innate immune response...
  63. ncbi Infectious bursal disease subunit vaccination
    Pedro Villegas
    Poultry Diagnostic and Research Center, University of Georgia, Athens, GA 30602, USA
    Avian Dis 52:670-4. 2008
    b>Infectious bursal disease virus (IBDV) is the causative agent of infectious bursal disease, a nosologic entity with global economic importance in poultry. The viral protein 2 (VP2) is recognized as the virus' major antigenic protein...
  64. pmc Non-Lytic Egression of Infectious Bursal Disease Virus (IBDV) Particles from Infected Cells
    Fernando Méndez
    Departamento de Biologia Molecular y Celular, Centro Nacional de Biotecnologia CSIC, Madrid, Spain
    PLoS ONE 12:e0170080. 2017
    b>Infectious bursal disease virus (IBDV), a member of the Birnaviridae family, is responsible for a devastating immunosuppressive disease affecting juvenile domestic chickens...
  65. doi Health evaluation of African penguins (<i>Spheniscus demersus</i>) in southern Africa
    Nola J Parsons
    Southern African Foundation for the Conservation of Coastal Birds, Bloubergrant Bayworld Centre for Research and Education, Port Elizabeth
    Onderstepoort J Vet Res 83:e1-e13. 2016
    ..pathogens tested: avian encephalomyelitis virus, avian infectious bronchitis virus, avian reovirus, infectious bursal disease virus, Newcastle disease virus, Mycoplasma gallisepticum and Mycoplasma synoviae...
  66. pmc Exchange of the C-terminal part of VP3 from very virulent infectious bursal disease virus results in an attenuated virus with a unique antigenic structure
    Hein J Boot
    Institute for Animal Science and Health, ID Lelystad, PO Box 65, NL 8200 AB Lelystad, The Netherlands
    J Virol 76:10346-55. 2002
    b>Infectious bursal disease virus (IBDV) is the major viral pathogen in the poultry industry. Live attenuated serotype 1 vaccine strains are commonly used to protect susceptible chickens during their first 6 weeks of life...
  67. ncbi A comparison of immune responses to infection with virulent infectious bursal disease virus (IBDV) between specific-pathogen-free chickens infected at 12 and 28 days of age
    Silke Rautenschlein
    Clinic for Poultry, University of Veterinary Medicine Hannover, Bunteweg 17, 30559 Hannover, Germany
    Vet Immunol Immunopathol 115:251-60. 2007
    Previous studies indicated that the pathogenesis of infectious bursal disease virus (IBDV) may vary depending on the age of the infected chicken...
  68. ncbi Characterization of Chicken Splenic-Derived Dendritic Cells Following Vaccine and Very Virulent Strains of Infectious Bursal Disease Virus Infection
    A R Yasmin
    a Institute of Bioscience
    Avian Dis 60:739-751. 2016
    Studies have shown that infectious bursal disease virus (IBDV) infects lymphoid cells, mainly B cells and macrophages...
  69. doi Molecular characterization of infectious bursal disease viruses from Pakistan
    Muhammad Zubair Shabbir
    Quality Operations Laboratory, University of Veterinary and Animal Sciences, Lahore, 54600, Pakistan
    Arch Virol 161:2001-6. 2016
    ..Here, we sequenced the hypervariable region (HVR) of the VP2 gene of circulating strains of infectious bursal disease virus (IBDV) originating from outbreaks (n = 4) in broiler flocks in Pakistan...
  70. ncbi A novel transcutaneous plasmid-dimethylsulfoxide delivery technique for avian nucleic acid immunization
    R A Heckert
    Virginia Maryland Regional College of Veterinary Medicine, University of Maryland, College Park, MD 20742 3711, USA
    Vet Immunol Immunopathol 89:67-81. 2002
    ..enhanced green fluorescent protein (EGFP) reporter gene and a bivalent DNA vaccine coding for infectious bursal disease virus (IBDV) and Newcastle disease virus (NDV) immunogenic protein genes...
  71. doi Identification and molecular analysis of infectious bursal disease in broiler farms in the Kurdistan Regional Government of Iraq
    Oumed Gerjis M Amin
    Animal Health Department, General Directorate of Animal Wealth and Veterinary, Ministry of Agriculture and Water Resources, Kurdistan Regional Government, Erbil, Iraq
    Trop Anim Health Prod 46:1297-301. 2014
    The present study was undertaken to characterize field isolates of infectious bursal disease virus (IBDV). The identification was done using reverse transcription-polymerase chain reaction (RT-PCR) and partial sequencing of the VP2 gene...
  72. doi Rapid subtyping of H9N2 influenza virus by a triple reverse transcription polymerase chain reaction
    Hao tai Chen
    Key Laboratory of Animal Virology of Ministry of Agriculture, State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China
    J Virol Methods 158:58-62. 2009
    ..negative for the other avian viruses including Newcastle disease virus, infectious bronchitis virus, infectious bursal disease virus, duck hepatitis virus and avian encephalomyelitis virus...
  73. ncbi Associations of BF2 alleles with antibody titres and production traits in commercial pure line broiler chickens
    S J Ewald
    Department of Pathobiology, Auburn University, Auburn, AL 36849 5519, USA
    Anim Genet 38:174-6. 2007
    ..Significant BF2 associations with a subset of traits were observed in two lines. The BF2*21 allele was positively associated with antibody titre to infectious bursal disease virus in both lines. Other associations were line-specific.
  74. ncbi Testing of a new disinfectant process for poultry viruses
    Lauren Gay
    College of Veterinary Medicine, Department of Population Health, University of Georgia, Athens, GA, USA
    Avian Dis 54:763-7. 2010
    ..for the ability to inactivate the infectivity of low-pathogenic avian influenza virus (LPAIV) and infectious bursal disease virus (IBDV), with virus-contaminated chicken litter used as the substrate...
  75. ncbi Proventriculitis in broiler chickens: effects of immunosuppression
    M J Pantin-Jackwood
    Department of Avian Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
    Avian Dis 48:300-16. 2004
    ..One such agent, infectious bursal disease virus (IBDV), has been implicated as a cause of proventriculitis, but a direct effect of this virus on the ..
  76. pmc Changes in the Cytokine and Toll-Like Receptor Gene Expression Following Infection of Indigenous and Commercial Chickens With Infectious bursal disease virus
    G Dhinakar raj
    Department of Animal Biotechnology, Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, Chennai, 600007 India
    Indian J Virol 22:146-51. 2011
    ..expression in 3 weeks old indigenous and commercial chickens infected with a very virulent strain of Infectious bursal disease virus (IBDV) was performed using a custom-made microarray chip...
  77. doi Fusion protein strategy to increase expression and solubility of hypervariable region of VP2 protein of infectious bursal disease virus in Escherichia coli
    Sahar Sadat Sedighzadeh
    National Institute of Genetic Engineering and Biotechnology NIGEB, P O Box 14155 6343, Tehran, Iran
    Protein J 31:580-4. 2012
    ..The NusA-hvVP2 protein was detected by a neutralizing monoclonal antibody, 1A6, in antigen-capture ELISA. In conclusion, the NusA protein is a suitable fusion partner to improve expression and solubility of the hvVP2 protein in E. coli...
  78. doi Inhibitory effect of Sargassum polysaccharide on oxidative stress induced by infectious bursa disease virus in chicken bursal lymphocytes
    Ling Zhang
    College of Animal Science and Technology, Guangxi University, Nanning, Guangxi, PR China
    Int J Biol Macromol 49:607-15. 2011
    ..the inhibitory effect of Sargassum polysaccharide on oxidative stress induced by infectious bursa disease virus (IBDV) in chicken bursal lymphocytes...
  79. doi An in vivo experimental model to determine antigenic variations among infectious bursal disease viruses
    Vijay Durairaj
    Poultry Diagnostic and Research Center, The University of Georgia, Athens, GA 30602, USA
    Avian Pathol 42:309-15. 2013
    b>Infectious bursal disease virus (IBDV) is a double-stranded RNA virus causing infectious bursal disease in chickens...
  80. ncbi Purification, crystallization and preliminary X-ray analysis of immunogenic virus-like particles formed by infectious bursal disease virus (IBDV) structural protein VP2
    Cheng Chung Lee
    Graduate Institute of Biotechnology, National Chung Hsing University, Taichung 40227, Taiwan
    Acta Crystallogr D Biol Crystallogr 59:1234-7. 2003
    b>Infectious bursal disease virus (IBDV) causes a highly contagious disease in young chicks and leads to significant economic losses in the poultry industry...
  81. doi Effective inhibition of replication of infectious bursal disease virus by miRNAs delivered by vectors and targeting the VP2 gene
    Yongjuan Wang
    College of Veterinary Medicine, Yangzhou University, Jiangsu 225009, China
    J Virol Methods 165:127-32. 2010
    RNA interference (RNAi) is a potent mechanism against a variety of viral infections. Infectious bursal disease virus (IBDV) causes an important disease economically in chickens, which is difficult to control...
  82. pmc Recombinant Marek's disease virus type 1 provides full protection against very virulent Marek's and infectious bursal disease viruses in chickens
    Kai Li
    Avian Immunosuppressive Diseases Division, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, P R China
    Sci Rep 6:39263. 2016
    ..bivalent vaccine based on MDV that confers full protection against both very virulent Marek's and infectious bursal disease virus (IBDV) infections in chickens has not been produced...
  83. pmc Infectious bursal disease virus is an icosahedral polyploid dsRNA virus
    Daniel Luque
    Department of Structure of Macromolecules, Centro Nacional de Biotecnologia CSIC, Cantoblanco, 28049 Madrid, Spain
    Proc Natl Acad Sci U S A 106:2148-52. 2009
    ..We performed an in-depth characterization of infectious bursal disease virus (IBDV), a non-enveloped icosahedral dsRNA virus with a bisegmented genome...
  84. ncbi Pathogenicity of Genome Reassortant Infectious Bursal Disease Viruses in Chickens and Turkeys
    Daral J Jackwood
    A Food Animal Health Research Program, Ohio Agricultural Research and Development Center, The Ohio State University, 1680 Madison Avenue, Wooster, OH 44691
    Avian Dis 60:765-772. 2016
    b>Infectious bursal disease virus (IBDV) contains two genome segments (segment A/segment B) that can reassort among the viruses. Reassortant IBDVs have been identified in several countries including the United States...
  85. ncbi Immunocytochemical techniques to investigate the pathogenesis of infectious micro-organisms and the concurrent immune response of the host
    S H Jeurissen
    Institute for Animal Science and Health ID DLO, Department of Immunology, Lelystad, The Netherlands
    Dev Comp Immunol 24:141-51. 2000
    ..Of the three techniques the results are described when applied on chicken tissues infected with various micro-organisms, such as Marek's disease virus, chicken anemia virus, infectious bursal disease virus and Eimeria tenella.
  86. doi Infectious bursal disease virus activates the phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway by interaction of VP5 protein with the p85α subunit of PI3K
    Li Wei
    Institute of Animal Husbandry and Veterinary Medicine, Beijing Municipal Academy of Agriculture and Forestry Sciences, No 9 Shuguang Garden Middle Road, Haidian District, Beijing 100097, People s Republic of China
    Virology 417:211-20. 2011
    ..The present study demonstrated for the first time that infectious bursal disease virus (IBDV), the causative agent of a highly contagious disease in chickens, can induce Akt ..
  87. ncbi Sequence analysis of both genome segments of three Croatian infectious bursal disease field viruses
    I Lojkic
    Croatian Veterinary Institute, Department for General Virology, Savska cesta 143, 10000 Zagreb, Croatia
    Avian Dis 52:513-9. 2008
    ..order to determine the mutations responsible for virulence, three Croatian field infectious bursal disease viruses (IBDV), designated Cro-Ig/02, Cro-Po/00, and Cro-Pa/98 were characterized...
  88. ncbi Small interfering RNAs inhibit infectious bursal disease virus replication in Vero cells
    B K Sajjanar
    Indian Veterinary Research Institute, Izatnagar, India
    Acta Virol 55:75-9. 2011
    ..This study was performed to analyze the application of siRNA against infectious bursal disease virus (IBDV) replication. Two siRNAs were designed to target common coding sequences of four IBDV proteins...
  89. doi Very Virulent Infectious Bursal Disease Virus Produces More-Severe Disease and Lesions in Specific-Pathogen-Free (SPF) Leghorns Than in SPF Broiler Chickens
    Mariana Sa e Silva
    a Southeast Poultry Research Laboratory, United States National Poultry Research Center, Agricultural Research Service, United States Department of Agriculture, 934 College Station Road, Athens, GA 30605
    Avian Dis 60:63-6. 2016
    b>Infectious bursal disease virus (IBDV) is an important pathogen of chickens causing negative economic impacts in poultry industries worldwide...
  90. ncbi Comparison of RNA and cDNA transfection methods for rescue of infectious bursal disease virus
    H J Boot
    Department of Avian Virology, Institute for Animal Science and Health, ID Lelystad, PO Box 65, NL 8200 AB, Lelystad, The Netherlands
    J Virol Methods 97:67-76. 2001
    ..transfection methods for the efficiency of transient protein expression and rescue of (recombinant) infectious bursal disease virus (IBDV)...
  91. doi Genome analysis and pathogenicity of reticuloendotheliosis virus isolated from a contaminated vaccine seed against infectious bursal disease virus: first report in China
    Yang Li
    College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai an 271018, PR China
    J Gen Virol 97:2809-2815. 2016
    Specific-pathogen-free (SPF) chickens were inoculated with the virus seed of an infectious bursal disease virus (IBDV)-attenuated vaccine, and positive reticuloendotheliosis virus (REV) antibody levels were subsequently detected in the ..
  92. ncbi Development of a multi-mimotope peptide as a vaccine immunogen for infectious bursal disease virus
    Yong shan Wang
    Laboratory of Biomolecular Engineering, Research Institute for Medicine of Nanjing Command, Center for Disease Control and Prevention of Nanjing Command, Nanjing 210002, China
    Vaccine 25:4447-55. 2007
    To explore the mimotope vaccine approach against infectious bursal disease virus (IBDV), five IBDV-specific monoclonal antibodies (mAbs) were prepared and their binding peptides were screened against a phage-displayed 12-mer peptide ..
  93. pmc Evaluation of modified vaccinia virus Ankara expressing VP2 protein of infectious bursal disease virus as an immunogen in chickens
    Flavia Adriana Zanetti
    Consejo Nacional de Investigaciones Cientificas y Tecnicas, Rivadavia 1917 C1033AAJ Ciudad Autónoma de Buenos Aires, Argentina
    J Vet Sci 13:199-201. 2012
    A recombinant modified vaccinia Ankara (MVA) virus expressing mature viral protein 2 (VP2) of the infectious bursal disease virus (IBDV) was constructed to develop MVA-based vaccines for poultry...
  94. pmc VP5 of infectious bursal disease virus is not essential for viral replication in cell culture
    E Mundt
    Institutes of Molecular and Cellular Virology, Friedrich Loeffler Institutes, Federal Research Center for Virus Diseases of Animals, Insel Riems, Germany
    J Virol 71:5647-51. 1997
    b>Infectious bursal disease virus (IBDV), a member of the Birnaviridae family, encodes in its bisegmented double-stranded RNA genome four structural virion proteins, VP1, VP2, VP3, and VP4, as well as a nonstructural protein, VP5...
  95. ncbi Day-old vaccination with live-in-oil vaccines: Newcastle disease (ND) and infectious bursal disease (IBD) in chicks and ND in turkey poults
    I Samina
    State Laboratory for Vaccine Control, Kimron Veterinary Instiute, Bet Dagan, Israel
    Avian Pathol 28:73-8. 1999
    ..bursal disease vaccine (IBD) incorporated in killed-in-oil combined ND + IBD vaccine, showed better protection against challenge with IBDV and higher antibody levels to NDV as compared to vaccination with killed-in-oil vaccine alone.
  96. ncbi Infectious bursal disease virus polyprotein expression arrests growth and mitogenic stimulation of B lymphocytes
    M A Peters
    Department of Veterinary Pathobiology, Purdue University, West Lafayette, Indiana 47907 2065, USA
    Arch Virol 149:2413-26. 2004
    b>Infectious bursal disease virus (IBDV) causes lymphocytolysis and immunosuppression in infected poultry...
  97. ncbi Prediction of optimal vaccination timing for infectious bursal disease based on chick weight
    Asaad Vaziry
    Faculty of Veterinary Medicine, University of Montreal, St Hyacinthe, Quebec, Canada
    Avian Dis 51:918-23. 2007
    ..from old and young breeders, respectively, and with different levels of maternal antibodies against infectious bursal disease virus (IBDV) were used in this study...
  98. ncbi [Inhibition of infectious bursal disease virus replication in chicken embryos by miRNAs delivered by recombinant avian adeno-associated viral vector]
    Pengpeng Shen
    College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China
    Wei Sheng Wu Xue Bao 51:256-61. 2011
    We studied the inhibition of infectious bursal disease virus (IBDV) replication in chicken embryos by recombinant avian adeno-associated virus (AAAV)-delivered VP1- and VP2-specific microRNAs (miRNAs).
  99. pmc Both genome segments contribute to the pathogenicity of very virulent infectious bursal disease virus
    Olivier Escaffre
    ANSES French Agency for Food, Environmental and Occupational Health and Safety, Avian and Rabbit Virology, Immunology and Parasitology Unit VIPAC, OIE Reference Laboratory for Infectious Bursal Disease, Ploufragan, France
    J Virol 87:2767-80. 2013
    b>Infectious bursal disease virus (IBDV) causes an economically significant disease of chickens worldwide. Very virulent IBDV (vvIBDV) strains have emerged and induce as much as 60% mortality...
  100. doi Molecular characteristic of VP2 gene of infectious bursal disease viruses isolated from a farm in two decades
    Yinju Li
    Animal Science and Technology College, Henan University of Science and Technology, Luoyang, 471003, People s Republic of China
    Virus Genes 38:408-13. 2009
    b>Infectious bursal disease virus (IBDV) is a double-stranded RNA virus in the Birnaviridae family. Four pathotypes, attenuated, virulent, antigenic variant, and very virulent, have been identified...
  101. pmc Host proteolytic activity is necessary for infectious bursal disease virus capsid protein assembly
    Nerea Irigoyen
    Department of Molecular and Cellular Biology, Centro Nacional de Biotecnologia CSIC, Cantoblanco, 28049 Madrid, Spain
    J Biol Chem 287:24473-82. 2012
    ..We show that the precursor of the VP2 capsid protein (pVP2) of the infectious bursal disease virus (IBDV), a double-stranded RNA virus, is processed at the C-terminal domain (CTD) by a host protease, ..

Research Grants4

  1. Edward H Egelman; Fiscal Year: 2016
    ..The proposed focus is on capsid proteins from bacteriophage P22, Infectious Bursal Disease Virus, and Murine Leukemia virus...
  2. HIGH SPEED HIGH RESOLUTION PHASE RESOLVED OCT/ODT
    Zhongping Chen; Fiscal Year: 2001
    ..abstract_text> ..
  3. Optical Biopsy Using MEMs Technology
    Zhongping Chen; Fiscal Year: 2006
    ..Finally, the scanning probe technology developed in this proposal can also be used for endoscopic confocal and two-photon imaging. ..
  4. Fourier Domain Functional OCT
    Zhongping Chen; Fiscal Year: 2009
    ....

Patents30

  1. COMPOSITIONS AND METHODS RELATED TO VIRAL VACCINES
    Patent Number: EP2870238-A2; Date:2015-05-13
  2. An infectious bursal disease virus mutant and vaccines
    Patent Number: EP1170302-A1; Date:2002-01-09
  3. Attenuated very virulent infectious bursal disease virus
    Patent Number: WO02096940-A2; Date:2002-12-05
  4. Serotype chimeric ibdv strains
    Patent Number: WO0192486-A1; Date:2001-12-06
  5. Mosaic infectious bursal disease virus vaccines
    Patent Number: EP1069187-A1; Date:2001-01-17
  6. Mosaic infectious bursal disease virus vaccines
    Patent Number: WO0104319-A1; Date:2001-01-18
  7. Genetically engineered cell culture adapted infectious bursal diseases virus (ibdv) mutants
    Patent Number: EP1035203-A1; Date:2000-09-13
  8. Preparation of Vaccine Master Cell Lines Using Recombinant Plant Suspension Cultures
    Patent Number: JP2009514547-A; Date:2009-04-09
  9. Avian Herpesvirus-based Recombinant Infectious Bursal Disease
    Patent Number: JP2004000111-A; Date:2004-01-08
  10. Stable Immunoprophylactic and Therapeutic Compositions Derived From Transgenic Plant Cells and Methods for Production
    Patent Number: JP2007526215-A; Date:2007-09-13
  11. NA vaccine comprising IBDV antigenic determinant sequence forpreventing infectious bursal disease
    Patent Number: KR1020040016198-A; Date:2004-03-10
  12. A broad spectrum infectious bursal disease virusvaccine
    Patent Number: KR1020010040325-A; Date:2001-07-06
  13. GENETICALLY ENGINEERED CELL CULTURE ADAPTED INFECTIOUS BURSALDISEASE VIRUS (IBDV) MUTANTS
    Patent Number: KR1020000010849-A; Date:2000-03-04
  14. VACCINE ACCELERATOR FACTOR (VAF) FOR IMPROVEMENT OF VACCINATIONS IN POULTRY
    Patent Number: JP2006524192-A; Date:2006-10-26
  15. Novel Infectious Bursal Disease Virus and Vaccine containing the
    Patent Number: WO2005100554-A; Date:2005-10-27
  16. MULTIPLE AND MULTIVALENT DNA VACCINES IN OVO
    Patent Number: JP2005519943-A; Date:2005-07-07
  17. RECOMBINANT NONPATHOGENIC MDV VECTOR PROVIDING MULTIVALENT IMMUNITY
    Patent Number: WO2013057235-A1; Date:2013-04-25
  18. Vaccine formulation against Gumboro disease
    Patent Number: EP1523992-A1; Date:2005-04-20
  19. METHODS AND REAGENTS FOR OBTAINING TRANSCRIPTIONALLY ACTIVE VIRUS-LIKE PARTICLES AND RECOMBINANT VIRIONS
    Patent Number: WO2012007557-A1; Date:2012-01-19
  20. Methods and reagents for obtaining transcriptionally active virus-like particles and recombinant virions
    Patent Number: EP2407534-A1; Date:2012-01-18
  21. Genetically engeneered cell culture adapted infectious bursal disease virus (IBDV) mutants
    Patent Number: JP2011036255-A; Date:2011-02-24
  22. Avian polynucleotide vaccine formula
    Patent Number: JP2009149608-A; Date:2009-07-09
  23. TURKEY HERPESVIRUS VECTOR AS A RECOMBINANT INFECTIOUS BURSAL DISEASE VACCINE
    Patent Number: WO9410321-A1; Date:1994-05-11
  24. Recombinant Avipox virus
    Patent Number: EP0517292-A1; Date:1992-12-09
  25. CLONING AND EXPRESSION OF HOST-PROTECTIVE IMMUNOGENS OF IBDV
    Patent Number: WO8607060-A1; Date:1986-12-04
  26. Broad-spectrum infectious bursal disease virus vaccine
    Patent Number: JP2002095485-A; Date:2002-04-02
  27. Avian polynucleotide vaccine formula
    Patent Number: JP2001503019-A; Date:2001-03-06
  28. An infectious bursal disease virus variant
    Patent Number: WO03074552-A1; Date:2003-09-12
  29. Avian herpes virus-based recombinant infectious bursal disease vaccine
    Patent Number: EP1298139-A2; Date:2003-04-02
  30. Compositions and methods for the treatment of viral hepatitis
    Patent Number: WO2008068661-A1; Date:2008-06-12