Sesbania mosaic virus

Summary

Alias: sesbania mosaic virus SMV

Top Publications

  1. ncbi Polyprotein processing: cis and trans proteolytic activities of Sesbania mosaic virus serine protease
    P S Satheshkumar
    Department of Biochemistry, Indian Institute of Science, Bangalore, 560 012, India
    Virology 318:429-38. 2004
  2. ncbi Structural studies on recombinant T = 3 capsids of Sesbania mosaic virus coat protein mutants
    V Sangita
    Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560012, India
    Acta Crystallogr D Biol Crystallogr 61:1402-5. 2005
  3. pmc Interaction of Sesbania mosaic virus movement protein with VPg and P10: implication to specificity of genome recognition
    Soumya Roy Chowdhury
    Department of Biochemistry, Indian Institute of Science, Bangalore, India
    PLoS ONE 6:e15609. 2011
  4. doi Interaction of Sesbania mosaic virus movement protein with the coat protein--implications for viral spread
    Soumya Roy Chowdhury
    Department of Biochemistry, Indian Institute of Science, Bangalore, India
    FEBS J 278:257-72. 2011
  5. doi Stacking interactions of W271 and H275 of SeMV serine protease with W43 of natively unfolded VPg confer catalytic activity to protease
    Smita Nair
    Department of Biochemistry, Indian Institute of Science, Bangalore 560012, Karnataka State, India
    Virology 382:83-90. 2008
  6. doi Primer-independent initiation of RNA synthesis by SeMV recombinant RNA-dependent RNA polymerase
    K Govind
    Indian Institute of Science, Bangalore 560012, Karnataka, India
    Virology 401:280-92. 2010
  7. doi Processing of SeMV polyproteins revisited
    Smita Nair
    Department of Biochemistry, Indian Institute of Science, Bangalore 560012, Karnataka State, India
    Virology 396:106-17. 2010
  8. ncbi "Natively unfolded" VPg is essential for Sesbania mosaic virus serine protease activity
    Panayampalli Subbian Satheshkumar
    Department of Biochemistry, Indian Institute of Science, Bangalore
    J Biol Chem 280:30291-300. 2005
  9. ncbi Complete nucleotide sequence of Sesbania mosaic virus: a new virus species of the genus Sobemovirus
    G L Lokesh
    Department of Biochemistry, Indian Institute of Science, Bangalore, India
    Arch Virol 146:209-23. 2001
  10. doi Biodistribution and toxicity evaluation of sesbania mosaic virus nanoparticles in mice
    G P Vishnu Vardhan
    Department of Virology, Sri Venkateswara University, Tirupati, Andhra Pradesh, India
    Arch Virol 161:2673-81. 2016

Research Grants

  1. ERIC ROBERT MAY; Fiscal Year: 2014

Scientific Experts

  • Mathur Rn Murthy
  • H S Savithri
  • P S Satheshkumar
  • Smita Nair
  • G L Lokesh
  • V Sangita
  • ERIC ROBERT MAY
  • Soumya Roy Chowdhury
  • Ashutosh Gulati
  • Ambily Abraham
  • Anju Pappachan
  • Handanahal S Savithri
  • Eric R May
  • Usha Natraj
  • Chetan Kumar Meena
  • Ankush Aggarwal
  • G P Vishnu Vardhan
  • Kazunori Matsuura
  • P Gayathri
  • Charles L Brooks
  • Kunduri Govind
  • C S Vijay
  • V Saravanan
  • K Govind
  • Handanahal Subbarao Savithri
  • Panayampalli Subbian Satheshkumar
  • Anjali A Karande
  • Sathyabalan Murugesan
  • Ayaluru Murali
  • Kalyani Mohan
  • Yusaku Mizuguchi
  • Nobuo Kimizuka
  • Pavithra Mukunda
  • Abhinandan Murthy
  • Subhomoi Borkotoky
  • William S Klug
  • M Hema
  • Kristiina Mäkinen
  • Subashchandrabose Chinnathambi
  • Chinnathambi Subashchandrabose
  • S S Krishna
  • K Prasad
  • Pananghat Gayathri
  • Kasaragod Prasad
  • T D S Gowri
  • K Gopinath
  • S K Munshi
  • C N Hiremath
  • M Sastri
  • D Prahadeeswaran

Detail Information

Publications27

  1. ncbi Polyprotein processing: cis and trans proteolytic activities of Sesbania mosaic virus serine protease
    P S Satheshkumar
    Department of Biochemistry, Indian Institute of Science, Bangalore, 560 012, India
    Virology 318:429-38. 2004
    b>Sesbania mosaic virus (SeMV) polyprotein was shown to undergo proteolytic processing when expressed in E. coli...
  2. ncbi Structural studies on recombinant T = 3 capsids of Sesbania mosaic virus coat protein mutants
    V Sangita
    Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560012, India
    Acta Crystallogr D Biol Crystallogr 61:1402-5. 2005
    When expressed in Escherichia coli, the recombinant coat protein (rCP) of Sesbania mosaic virus (SeMV) was shown to self-assemble into T = 3 capsids encapsidating CP mRNA and 23S rRNA derived from the host...
  3. pmc Interaction of Sesbania mosaic virus movement protein with VPg and P10: implication to specificity of genome recognition
    Soumya Roy Chowdhury
    Department of Biochemistry, Indian Institute of Science, Bangalore, India
    PLoS ONE 6:e15609. 2011
    b>Sesbania mosaic virus (SeMV) is a single strand positive-sense RNA plant virus that belongs to the genus Sobemovirus. The mechanism of cell-to-cell movement in sobemoviruses has not been well studied...
  4. doi Interaction of Sesbania mosaic virus movement protein with the coat protein--implications for viral spread
    Soumya Roy Chowdhury
    Department of Biochemistry, Indian Institute of Science, Bangalore, India
    FEBS J 278:257-72. 2011
    b>Sesbania mosaic virus (SeMV) is a single-stranded positive-sense RNA plant virus belonging to the genus Sobemovirus...
  5. doi Stacking interactions of W271 and H275 of SeMV serine protease with W43 of natively unfolded VPg confer catalytic activity to protease
    Smita Nair
    Department of Biochemistry, Indian Institute of Science, Bangalore 560012, Karnataka State, India
    Virology 382:83-90. 2008
    N-terminal serine protease domain of Sesbania mosaic virus polyprotein, requires fused VPg for its activity. W43 of VPg mediates aromatic stacking interactions (characterized by 230 nm positive CD peak) with protease...
  6. doi Primer-independent initiation of RNA synthesis by SeMV recombinant RNA-dependent RNA polymerase
    K Govind
    Indian Institute of Science, Bangalore 560012, Karnataka, India
    Virology 401:280-92. 2010
    b>Sesbania mosaic virus (SeMV), a single-strand positive-sense RNA plant virus, belongs to the genus Sobemoviruses. Mechanism of replication in Sobemoviruses is poorly understood...
  7. doi Processing of SeMV polyproteins revisited
    Smita Nair
    Department of Biochemistry, Indian Institute of Science, Bangalore 560012, Karnataka State, India
    Virology 396:106-17. 2010
    Processing of Sesbania mosaic virus (SeMV) polyprotein 2a and 2ab was reanalyzed in the view of the new genome organization of sobemoviruses. Polyprotein 2a when expressed in E...
  8. ncbi "Natively unfolded" VPg is essential for Sesbania mosaic virus serine protease activity
    Panayampalli Subbian Satheshkumar
    Department of Biochemistry, Indian Institute of Science, Bangalore
    J Biol Chem 280:30291-300. 2005
    ..In Sesbania mosaic virus, open reading frame-2 codes for a polyprotein that is cleaved into different functional proteins in cis by ..
  9. ncbi Complete nucleotide sequence of Sesbania mosaic virus: a new virus species of the genus Sobemovirus
    G L Lokesh
    Department of Biochemistry, Indian Institute of Science, Bangalore, India
    Arch Virol 146:209-23. 2001
    The complete nucleotide sequence of the Sesbania mosaic virus (SeMV) genomic RNA was determined by sequencing overlapping cDNA clones...
  10. doi Biodistribution and toxicity evaluation of sesbania mosaic virus nanoparticles in mice
    G P Vishnu Vardhan
    Department of Virology, Sri Venkateswara University, Tirupati, Andhra Pradesh, India
    Arch Virol 161:2673-81. 2016
    b>Sesbania mosaic virus (SeMV), a 30-nm spherical plant sobemovirus, is suitable for developing functionalized nanoparticles for biomedical applications...
  11. doi Insight into virus encapsulation mechanism through in silico interaction study between coat protein and RNA operator loops of Sesbania mosaic virus
    Chetan Kumar Meena
    Centre for Bioinformatics, School of Life Sciences, Pondicherry University, Puducherry 605 014, India
    Mol Biosyst 12:1996-2009. 2016
    ..b>Sesbania mosaic virus (SeMV) is a spherical virus and its capsid is formed by a coat protein, which contains the Arginine Rich ..
  12. pmc Intracellular delivery of antibodies by chimeric Sesbania mosaic virus (SeMV) virus like particles
    Ambily Abraham
    Department of Biochemistry, Indian Institute of Science, Karnataka, India
    Sci Rep 6:21803. 2016
    ..For this purpose, Sesbania mosaic virus coat protein (CP) was genetically engineered with the B domain of Staphylococcus aureus protein A (SpA) at ..
  13. doi Nonuniform elastic properties of macromolecules and effect of prestrain on their continuum nature
    Ankush Aggarwal
    Zienkiewicz Centre for Computational Engineering, Swansea University, Swansea SA1 8EN, United Kigdom
    Phys Rev E 93:012417. 2016
    ..We present the results for a mutant of Sesbania mosaic virus capsid, where we calculate the elastic moduli at different scales and observe an apparent problem with the ..
  14. doi Structural studies on chimeric Sesbania mosaic virus coat protein: Revisiting SeMV assembly
    Ashutosh Gulati
    Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560012, India
    Virology 489:34-43. 2016
    The capsid protein (CP) of Sesbania mosaic virus (SeMV, a T=3 plant virus) consists of a disordered N-terminal R-domain and an ordered S-domain. Removal of the R-domain results in the formation of T=1 particles...
  15. doi Peptide nanospheres self-assembled from a modified β-annulus peptide of Sesbania mosaic virus
    Kazunori Matsuura
    Department of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University, Tottori, Japan
    Biopolymers 106:470-5. 2016
    A novel β-annulus peptide of Sesbania mosaic virus bearing an FKFE sequence at the C terminus was synthesized, and its self-assembling behavior in water was investigated...
  16. ncbi Structure of a mutant T=1 capsid of Sesbania mosaic virus: role of water molecules in capsid architecture and integrity
    V Sangita
    Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560012, India
    Acta Crystallogr D Biol Crystallogr 61:1406-12. 2005
    Deletion of the N-terminal 31 amino acids from the coat protein (CP) of Sesbania mosaic virus (SeMV) results in the formation of T = 1 capsids...
  17. ncbi The role of arginine-rich motif and beta-annulus in the assembly and stability of Sesbania mosaic virus capsids
    P S Satheshkumar
    Department of Biochemistry, Indian Institute of Science, Bangalore 560 012, India
    J Mol Biol 353:447-58. 2005
    b>Sesbania mosaic virus (SeMV) capsids are stabilized by protein-protein, protein-RNA and calcium-mediated protein-protein interactions...
  18. ncbi Role of metal ion-mediated interactions in the assembly and stability of Sesbania mosaic virus T=3 and T=1 capsids
    P S Satheshkumar
    Department of Biochemistry, Indian Institute of Science, Bangalore 560 012, India
    J Mol Biol 342:1001-14. 2004
    b>Sesbania mosaic virus (SeMV) capsids are stabilized by RNA-protein, protein-protein and calcium-mediated protein-protein interactions. The removal of calcium has been proposed to be a prerequisite for the disassembly of the virus...
  19. ncbi T=1 capsid structures of Sesbania mosaic virus coat protein mutants: determinants of T=3 and T=1 capsid assembly
    V Sangita
    Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560012, India
    J Mol Biol 342:987-99. 2004
    b>Sesbania mosaic virus particles consist of 180 coat protein subunits of 29kDa organized on a T=3 icosahedral lattice...
  20. ncbi A molecular switch in the capsid protein controls the particle polymorphism in an icosahedral virus
    G L Lokesh
    Department of Biochemistry, Indian Institute of Science, Bangalore 560 012, India
    Virology 292:211-23. 2002
    The recombinant coat protein (CP) of Sesbania mosaic virus (SeMV; genus Sobemovirus) was found to self-assemble into capsids encapsidating 23S rRNA and CP mRNA in Escherichia coli...
  21. pmc Sesbania mosaic virus (SeMV) infectious clone: possible mechanism of 3' and 5' end repair and role of polyprotein processing in viral replication
    Kunduri Govind
    Indian Institute of Science, Bangalore, Karnataka, India
    PLoS ONE 7:e31190. 2012
    b>Sesbania mosaic virus (SeMV) is a positive stranded RNA virus belonging to the genus Sobemovirus. Construction of an infectious clone is an essential step for deciphering the virus gene functions in vivo...
  22. doi Natively unfolded nucleic acid binding P8 domain of SeMV polyprotein 2a affects the novel ATPase activity of the preceding P10 domain
    Smita Nair
    Department of Biochemistry, Indian Institute of Science, Bangalore, Karnataka State, India
    FEBS Lett 584:571-6. 2010
    Open reading frame (ORF) 2a of Sesbania mosaic virus (SeMV) codes for polyprotein 2a (Membrane anchor-protease-VPg-P10-P8)...
  23. doi A single point mutation disrupts the capsid assembly in Sesbania Mosaic Virus resulting in a stable isolated dimer
    Anju Pappachan
    Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India
    Virology 392:215-21. 2009
    ..capturing smaller oligomers, interfacial residue mutations were carried out in the coat protein gene of Sesbania Mosaic Virus, a T=3 ss (+) RNA plant virus...
  24. doi Structure of recombinant capsids formed by the beta-annulus deletion mutant -- rCP (Delta48-59) of Sesbania mosaic virus
    Anju Pappachan
    Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India
    Virology 375:190-6. 2008
    ..In order to examine the importance of the beta-annulus, a deletion mutant of Sesbania mosaic virus coat protein in which residues 48-59 involved in the formation of the beta-annulus were deleted retaining ..
  25. ncbi Crystal structure of the serine protease domain of Sesbania mosaic virus polyprotein and mutational analysis of residues forming the S1-binding pocket
    P Gayathri
    Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India
    Virology 346:440-51. 2006
    b>Sesbania mosaic virus (SeMV) polyprotein is processed by its N-terminal serine protease domain. The crystal structure of the protease domain was determined to a resolution of 2...
  26. pmc Determination of viral capsid elastic properties from equilibrium thermal fluctuations
    Eric R May
    Department of Chemistry and Biophysics Program, University of Michigan, Ann Arbor, 48109, USA
    Phys Rev Lett 106:188101. 2011
    ..method we calculate the two-dimensional Young's modulus Y, bending modulus κ, and Föppl-von Kármán number γ, for the T=1 mutant of the Sesbania mosaic virus. The values determined are in the range of previous theoretical estimates.
  27. ncbi Three-dimensional structure of physalis mottle virus: implications for the viral assembly
    S S Krishna
    Molecular Biophysics Unit, Indian Institute of Science Bangalore, 560 012, India
    J Mol Biol 289:919-34. 1999
    ..Comparison of PhMV with the sobemovirus, sesbania mosaic virus reveals striking similarities in the overall tertiary fold of the coat protein although the capsid ..

Research Grants1

  1. ERIC ROBERT MAY; Fiscal Year: 2014
    ..I have conducted simulations of several virus systems so far, including Sesbania mosaic virus, cowpea chlorotic mottle virus, HK97, hepatitis B virus, and Norwalk virus...