sinorhizobium meliloti

Summary

Summary: A species of gram-negative, aerobic bacteria that causes formation of root nodules on some, but not all, types of sweet clover, MEDICAGO SATIVA, and fenugreek.

Top Publications

  1. Zurdo Piñeiro J, García Fraile P, Rivas R, Peix A, León Barrios M, Willems A, et al. Rhizobia from Lanzarote, the Canary Islands, that nodulate Phaseolus vulgaris have characteristics in common with Sinorhizobium meliloti isolates from mainland Spain. Appl Environ Microbiol. 2009;75:2354-9 pubmed publisher
    ..soil of Lanzarote, an island of the Canary Islands, were identical to a less-common pattern found within Sinorhizobium meliloti (assigned to group II) obtained from nodules of alfalfa and alfalfa-related legumes grown in northern ..
  2. Poysti N, Oresnik I. Characterization of Sinorhizobium meliloti triose phosphate isomerase genes. J Bacteriol. 2007;189:3445-51 pubmed
    A Tn5 mutant strain of Sinorhizobium meliloti with an insertion in tpiA (systematic identifier SMc01023), a putative triose phosphate isomerase (TPI)-encoding gene, was isolated...
  3. Pucciariello C, Innocenti G, Van de Velde W, Lambert A, Hopkins J, Clement M, et al. (Homo)glutathione depletion modulates host gene expression during the symbiotic interaction between Medicago truncatula and Sinorhizobium meliloti. Plant Physiol. 2009;151:1186-96 pubmed publisher
    ..truncatula. In this study, the plant transcriptomic response to Sinorhizobium meliloti infection under (h)GSH depletion was investigated using cDNA-amplified fragment length polymorphism ..
  4. Nogales J, Bernabéu Roda L, Cuéllar V, Soto M. ExpR is not required for swarming but promotes sliding in Sinorhizobium meliloti. J Bacteriol. 2012;194:2027-35 pubmed publisher
    ..It has been reported that the swarming ability of the soil bacterium Sinorhizobium meliloti Rm2011 requires a functional ExpR/Sin quorum-sensing system...
  5. Pini F, Frage B, Ferri L, De Nisco N, Mohapatra S, Taddei L, et al. The DivJ, CbrA and PleC system controls DivK phosphorylation and symbiosis in Sinorhizobium meliloti. Mol Microbiol. 2013;90:54-71 pubmed publisher
    b>Sinorhizobium meliloti is a soil bacterium that invades the root nodules it induces on Medicago sativa, whereupon it undergoes an alteration of its cell cycle and differentiates into nitrogen-fixing, elongated and polyploid bacteroid with ..
  6. Lohar D, Haridas S, Gantt J, VandenBosch K. A transient decrease in reactive oxygen species in roots leads to root hair deformation in the legume-rhizobia symbiosis. New Phytol. 2007;173:39-49 pubmed
    ..The results suggest a role for the transient reduction of ROS accumulation in governing NF-induced root hair deformation in legumes. ..
  7. Smit P, Limpens E, Geurts R, Fedorova E, Dolgikh E, Gough C, et al. Medicago LYK3, an entry receptor in rhizobial nodulation factor signaling. Plant Physiol. 2007;145:183-91 pubmed
    ..Therefore, LYK3 functions as the proposed entry receptor, specifically controlling infection. Finally, we show that LYK3, which regulates a subset of Nod factor-induced genes, is not required for the induction of NODULE INCEPTION. ..
  8. Gu X, Lee S, Bar Peled M. Biosynthesis of UDP-xylose and UDP-arabinose in Sinorhizobium meliloti 1021: first characterization of a bacterial UDP-xylose synthase, and UDP-xylose 4-epimerase. Microbiology. 2011;157:260-9 pubmed publisher
    b>Sinorhizobium meliloti is a soil bacterium that fixes nitrogen after being established inside nodules that can form on the roots of several legumes, including Medicago truncatula. A mutation in an S...
  9. Gao M, Chen H, Eberhard A, Gronquist M, Robinson J, Connolly M, et al. Effects of AiiA-mediated quorum quenching in Sinorhizobium meliloti on quorum-sensing signals, proteome patterns, and symbiotic interactions. Mol Plant Microbe Interact. 2007;20:843-56 pubmed
    ..approach was used here to identify QS-regulated behaviors in the N-fixing bacterial symbiont Sinorhizobium meliloti. The AiiA lactonase from Bacillus produced in S. meliloti was shown to enzymatically inactivate S...
  10. Sauviac L, Philippe H, Phok K, Bruand C. An extracytoplasmic function sigma factor acts as a general stress response regulator in Sinorhizobium meliloti. J Bacteriol. 2007;189:4204-16 pubmed
    b>Sinorhizobium meliloti genes transcriptionally up-regulated after heat stress, as well as upon entry into stationary phase, were identified by microarray analyses...

Locale

Detail Information

Publications137 found, 100 shown here

  1. Zurdo Piñeiro J, García Fraile P, Rivas R, Peix A, León Barrios M, Willems A, et al. Rhizobia from Lanzarote, the Canary Islands, that nodulate Phaseolus vulgaris have characteristics in common with Sinorhizobium meliloti isolates from mainland Spain. Appl Environ Microbiol. 2009;75:2354-9 pubmed publisher
    ..soil of Lanzarote, an island of the Canary Islands, were identical to a less-common pattern found within Sinorhizobium meliloti (assigned to group II) obtained from nodules of alfalfa and alfalfa-related legumes grown in northern ..
  2. Poysti N, Oresnik I. Characterization of Sinorhizobium meliloti triose phosphate isomerase genes. J Bacteriol. 2007;189:3445-51 pubmed
    A Tn5 mutant strain of Sinorhizobium meliloti with an insertion in tpiA (systematic identifier SMc01023), a putative triose phosphate isomerase (TPI)-encoding gene, was isolated...
  3. Pucciariello C, Innocenti G, Van de Velde W, Lambert A, Hopkins J, Clement M, et al. (Homo)glutathione depletion modulates host gene expression during the symbiotic interaction between Medicago truncatula and Sinorhizobium meliloti. Plant Physiol. 2009;151:1186-96 pubmed publisher
    ..truncatula. In this study, the plant transcriptomic response to Sinorhizobium meliloti infection under (h)GSH depletion was investigated using cDNA-amplified fragment length polymorphism ..
  4. Nogales J, Bernabéu Roda L, Cuéllar V, Soto M. ExpR is not required for swarming but promotes sliding in Sinorhizobium meliloti. J Bacteriol. 2012;194:2027-35 pubmed publisher
    ..It has been reported that the swarming ability of the soil bacterium Sinorhizobium meliloti Rm2011 requires a functional ExpR/Sin quorum-sensing system...
  5. Pini F, Frage B, Ferri L, De Nisco N, Mohapatra S, Taddei L, et al. The DivJ, CbrA and PleC system controls DivK phosphorylation and symbiosis in Sinorhizobium meliloti. Mol Microbiol. 2013;90:54-71 pubmed publisher
    b>Sinorhizobium meliloti is a soil bacterium that invades the root nodules it induces on Medicago sativa, whereupon it undergoes an alteration of its cell cycle and differentiates into nitrogen-fixing, elongated and polyploid bacteroid with ..
  6. Lohar D, Haridas S, Gantt J, VandenBosch K. A transient decrease in reactive oxygen species in roots leads to root hair deformation in the legume-rhizobia symbiosis. New Phytol. 2007;173:39-49 pubmed
    ..The results suggest a role for the transient reduction of ROS accumulation in governing NF-induced root hair deformation in legumes. ..
  7. Smit P, Limpens E, Geurts R, Fedorova E, Dolgikh E, Gough C, et al. Medicago LYK3, an entry receptor in rhizobial nodulation factor signaling. Plant Physiol. 2007;145:183-91 pubmed
    ..Therefore, LYK3 functions as the proposed entry receptor, specifically controlling infection. Finally, we show that LYK3, which regulates a subset of Nod factor-induced genes, is not required for the induction of NODULE INCEPTION. ..
  8. Gu X, Lee S, Bar Peled M. Biosynthesis of UDP-xylose and UDP-arabinose in Sinorhizobium meliloti 1021: first characterization of a bacterial UDP-xylose synthase, and UDP-xylose 4-epimerase. Microbiology. 2011;157:260-9 pubmed publisher
    b>Sinorhizobium meliloti is a soil bacterium that fixes nitrogen after being established inside nodules that can form on the roots of several legumes, including Medicago truncatula. A mutation in an S...
  9. Gao M, Chen H, Eberhard A, Gronquist M, Robinson J, Connolly M, et al. Effects of AiiA-mediated quorum quenching in Sinorhizobium meliloti on quorum-sensing signals, proteome patterns, and symbiotic interactions. Mol Plant Microbe Interact. 2007;20:843-56 pubmed
    ..approach was used here to identify QS-regulated behaviors in the N-fixing bacterial symbiont Sinorhizobium meliloti. The AiiA lactonase from Bacillus produced in S. meliloti was shown to enzymatically inactivate S...
  10. Sauviac L, Philippe H, Phok K, Bruand C. An extracytoplasmic function sigma factor acts as a general stress response regulator in Sinorhizobium meliloti. J Bacteriol. 2007;189:4204-16 pubmed
    b>Sinorhizobium meliloti genes transcriptionally up-regulated after heat stress, as well as upon entry into stationary phase, were identified by microarray analyses...
  11. Simsek S, Ojanen Reuhs T, Stephens S, Reuhs B. Strain-ecotype specificity in Sinorhizobium meliloti-Medicago truncatula symbiosis is correlated to succinoglycan oligosaccharide structure. J Bacteriol. 2007;189:7733-40 pubmed
    ..are necessary for the establishment of nitrogen-fixing nodules (Fix+) in Medicago truncatula-Sinorhizobium meliloti symbiosis. This report shows that M. truncatula-S...
  12. Nogales J, Domínguez Ferreras A, Amaya Gómez C, van Dillewijn P, Cuéllar V, Sanjuan J, et al. Transcriptome profiling of a Sinorhizobium meliloti fadD mutant reveals the role of rhizobactin 1021 biosynthesis and regulation genes in the control of swarming. BMC Genomics. 2010;11:157 pubmed publisher
    ..In Sinorhizobium meliloti this type of motility has been described in a fadD mutant...
  13. Diaz R, Vargas Lagunas C, Villalobos M, Peralta H, Mora Y, Encarnación S, et al. argC Orthologs from Rhizobiales show diverse profiles of transcriptional efficiency and functionality in Sinorhizobium meliloti. J Bacteriol. 2011;193:460-72 pubmed publisher
    ..the transcriptional expression and metabolic performance of ortholog substitution complementing a Sinorhizobium meliloti argC mutant with argC from Rhizobiales (Agrobacterium tumefaciens, Rhizobium etli, and Mesorhizobium loti)...
  14. Tu C, Teng Y, Luo Y, Li X, Sun X, Li Z, et al. Potential for biodegradation of polychlorinated biphenyls (PCBs) by Sinorhizobium meliloti. J Hazard Mater. 2011;186:1438-44 pubmed publisher
    ..capability and metabolic intermediate of polychlorinated biphenyls (PCBs) by a rhizobial strain Sinorhizobium meliloti. Biodegradation was observed immediately after 2,4,4'-TCB was supplied as a sole source of carbon and ..
  15. Fontenelle C, Blanco C, Arrieta M, Dufour V, Trautwetter A. Resistance to organic hydroperoxides requires ohr and ohrR genes in Sinorhizobium meliloti. BMC Microbiol. 2011;11:100 pubmed publisher
    b>Sinorhizobium meliloti is a symbiotic nitrogen-fixing bacterium that elicits nodules on roots of host plants Medicago sativa. During nodule formation bacteria have to withstand oxygen radicals produced by the plant...
  16. Pauly N, Ferrari C, Andrio E, Marino D, Piardi S, Brouquisse R, et al. MtNOA1/RIF1 modulates Medicago truncatula-Sinorhizobium meliloti nodule development without affecting its nitric oxide content. J Exp Bot. 2011;62:939-48 pubmed publisher
    ..of an AtNoa1/Rif1 orthologue from Medicago truncatula (MtNoa1/Rif1) during its symbiotic interaction with Sinorhizobium meliloti has been studied...
  17. Ye H, Gemperline E, Venkateshwaran M, Chen R, Delaux P, Howes Podoll M, et al. MALDI mass spectrometry-assisted molecular imaging of metabolites during nitrogen fixation in the Medicago truncatula-Sinorhizobium meliloti symbiosis. Plant J. 2013;75:130-145 pubmed publisher
    ..The Medicago truncatula-Sinorhizobium meliloti association is an excellent model for dissecting this nitrogen-fixing symbiosis because of the ..
  18. Mueller K, Gonz lez J. Complex regulation of symbiotic functions is coordinated by MucR and quorum sensing in Sinorhizobium meliloti. J Bacteriol. 2011;193:485-96 pubmed publisher
    In Sinorhizobium meliloti, the production of exopolysaccharides such as succinoglycan and exopolysaccharide II (EPS II) enables the bacterium to invade root nodules on Medicago sativa and establish a nitrogen-fixing symbiosis...
  19. Liu W, Kohlen W, Lillo A, Op den Camp R, Ivanov S, Hartog M, et al. Strigolactone biosynthesis in Medicago truncatula and rice requires the symbiotic GRAS-type transcription factors NSP1 and NSP2. Plant Cell. 2011;23:3853-65 pubmed publisher
    ..NSP1 and NSP2 are single-copy genes in legumes, which implies that both proteins fulfill dual regulatory functions to control downstream targets after rhizobium-induced signaling as well as SL biosynthesis in nonsymbiotic conditions...
  20. Sorroche F, Spesia M, Zorreguieta A, Giordano W. A positive correlation between bacterial autoaggregation and biofilm formation in native Sinorhizobium meliloti isolates from Argentina. Appl Environ Microbiol. 2012;78:4092-101 pubmed publisher
    b>Sinorhizobium meliloti is a symbiotic nitrogen-fixing bacterium that elicits nodule formation on roots of alfalfa plants. S. meliloti produces two exopolysaccharides (EPSs), termed EPS I and EPS II, that are both able to promote symbiosis...
  21. Pii Y, Crimi M, Cremonese G, Spena A, Pandolfini T. Auxin and nitric oxide control indeterminate nodule formation. BMC Plant Biol. 2007;7:21 pubmed
    ..We have addressed the effects of bacterial auxin (IAA) on nodulation by using Sinorhizobium meliloti and Rhizobium leguminosarum bacteria genetically engineered for increased auxin synthesis...
  22. Lefebvre B, Timmers T, Mbengue M, Moreau S, Herve C, Toth K, et al. A remorin protein interacts with symbiotic receptors and regulates bacterial infection. Proc Natl Acad Sci U S A. 2010;107:2343-8 pubmed publisher
    ..We used root nodule symbiosis between Medicago truncatula and Sinorhizobium meliloti to study the roles of a remorin that is specifically induced during nodulation...
  23. Rinaudi L, Sorroche F, Zorreguieta A, Giordano W. Analysis of the mucR gene regulating biosynthesis of exopolysaccharides: implications for biofilm formation in Sinorhizobium meliloti Rm1021. FEMS Microbiol Lett. 2010;302:15-21 pubmed publisher
    ..In Sinorhizobium meliloti, the regulatory protein MucR controls exopolysaccharide production...
  24. Meilhoc E, Cam Y, Skapski A, Bruand C. The response to nitric oxide of the nitrogen-fixing symbiont Sinorhizobium meliloti. Mol Plant Microbe Interact. 2010;23:748-59 pubmed publisher
    ..of NO during the symbiotic interaction between the model legume Medicago truncatula and its symbiont Sinorhizobium meliloti have been reported but the role of NO in symbiosis is far from being elucidated...
  25. Jones K, Sharopova N, Lohar D, Zhang J, VandenBosch K, Walker G. Differential response of the plant Medicago truncatula to its symbiont Sinorhizobium meliloti or an exopolysaccharide-deficient mutant. Proc Natl Acad Sci U S A. 2008;105:704-9 pubmed publisher
    b>Sinorhizobium meliloti forms symbiotic, nitrogen-fixing nodules on the roots of Medicago truncatula. The bacteria invade and colonize the roots through structures called infection threads. S...
  26. Bittner A, Foltz A, Oke V. Only one of five groEL genes is required for viability and successful symbiosis in Sinorhizobium meliloti. J Bacteriol. 2007;189:1884-9 pubmed
    ..In particular, in Sinorhizobium meliloti there are four groESL operons and one groEL gene...
  27. Wells D, Chen E, Fisher R, Long S. ExoR is genetically coupled to the ExoS-ChvI two-component system and located in the periplasm of Sinorhizobium meliloti. Mol Microbiol. 2007;64:647-64 pubmed
    b>Sinorhizobium meliloti enters into a symbiotic relationship with legume host plants, providing fixed nitrogen in exchange for carbon and amino acids. In S...
  28. Horchani F, Pr vot M, Boscari A, Evangelisti E, Meilhoc E, Bruand C, et al. Both plant and bacterial nitrate reductases contribute to nitric oxide production in Medicago truncatula nitrogen-fixing nodules. Plant Physiol. 2011;155:1023-36 pubmed publisher
    ..truncatula-Sinorhizobium meliloti nodules under normoxic and hypoxic conditions...
  29. Schneiker Bekel S, Wibberg D, Bekel T, Blom J, Linke B, Neuweger H, et al. The complete genome sequence of the dominant Sinorhizobium meliloti field isolate SM11 extends the S. meliloti pan-genome. J Biotechnol. 2011;155:20-33 pubmed publisher
    Isolates of the symbiotic nitrogen-fixing species Sinorhizobium meliloti usually contain a chromosome and two large megaplasmids encoding functions that are absolutely required for the specific interaction of the microsymbiont with ..
  30. Schlüter J, Reinkensmeier J, Barnett M, Lang C, Krol E, Giegerich R, et al. Global mapping of transcription start sites and promoter motifs in the symbiotic α-proteobacterium Sinorhizobium meliloti 1021. BMC Genomics. 2013;14:156 pubmed publisher
    b>Sinorhizobium meliloti is a soil-dwelling α-proteobacterium that possesses a large, tripartite genome and engages in a nitrogen fixing symbiosis with its plant hosts...
  31. Rossbach S, Mai D, Carter E, Sauviac L, Capela D, Bruand C, et al. Response of Sinorhizobium meliloti to elevated concentrations of cadmium and zinc. Appl Environ Microbiol. 2008;74:4218-21 pubmed publisher
    Whole-genome transcriptional profiling was used to identify genes in Sinorhizobium meliloti 1021 that are differentially expressed during exposure to elevated concentrations of cadmium and zinc...
  32. Ratcliff W, Denison R. Individual-level bet hedging in the bacterium Sinorhizobium meliloti. Curr Biol. 2010;20:1740-4 pubmed publisher
    ..b>Sinorhizobium meliloti stores carbon and energy in poly-3-hydroxybutyrate (PHB) as a contingency against carbon scarcity...
  33. Moreau S, Verdenaud M, Ott T, Letort S, de Billy F, Niebel A, et al. Transcription reprogramming during root nodule development in Medicago truncatula. PLoS ONE. 2011;6:e16463 pubmed publisher
    ..have been used to study the transcriptome of root nodules induced by either wild type or mutant strains of Sinorhizobium meliloti. In this way we have defined eight major activation patterns in nodules and identified associated ..
  34. Del Giudice J, Cam Y, Damiani I, Fung Chat F, Meilhoc E, Bruand C, et al. Nitric oxide is required for an optimal establishment of the Medicago truncatula-Sinorhizobium meliloti symbiosis. New Phytol. 2011;191:405-17 pubmed publisher
    ..we detected NO production in the first steps, during infection threads growth, of the Medicago truncatula-Sinorhizobium meliloti symbiotic interaction. Nitric oxide was also detected, by confocal microscopy, in nodule primordia...
  35. Cheng J, Poduska B, Morton R, Finan T. An ABC-type cobalt transport system is essential for growth of Sinorhizobium meliloti at trace metal concentrations. J Bacteriol. 2011;193:4405-16 pubmed publisher
    We report expression and mutant phenotypes for a gene cluster in Sinorhizobium meliloti, designated cbtJKL, that has been shown to encode an ABC-type cobalt transport system...
  36. van Noorden G, Kerim T, Goffard N, Wiblin R, Pellerone F, Rolfe B, et al. Overlap of proteome changes in Medicago truncatula in response to auxin and Sinorhizobium meliloti. Plant Physiol. 2007;144:1115-31 pubmed
    ..mass spectrometry to compare proteomes of wild-type and sunn mutant roots after 24 h of treatment with Sinorhizobium meliloti, auxin, or a control. We identified 131 of 270 proteins responding to treatment with S...
  37. Larrainzar E, Wienkoop S, Weckwerth W, Ladrera R, Arrese Igor C, Gonzalez E. Medicago truncatula root nodule proteome analysis reveals differential plant and bacteroid responses to drought stress. Plant Physiol. 2007;144:1495-507 pubmed
    ..Drought was imposed on Medicago truncatula 'Jemalong A17' plants grown in symbiosis with Sinorhizobium meliloti strain 2011...
  38. Flechard M, Fontenelle C, Trautwetter A, Ermel G, Blanco C. Sinorhizobium meliloti rpoE2 is necessary for H(2)O(2) stress resistance during the stationary growth phase. FEMS Microbiol Lett. 2009;290:25-31 pubmed publisher
    RpoE2 is an extracytoplasmic sigma factor produced by Sinorhizobium meliloti during stationary growth phase. Its inactivation affected the synthesis of the superoxide dismutase, SodC, and catalase, KatC...
  39. Zaheer R, Morton R, Proudfoot M, Yakunin A, Finan T. Genetic and biochemical properties of an alkaline phosphatase PhoX family protein found in many bacteria. Environ Microbiol. 2009;11:1572-87 pubmed publisher
    ..and genetic regulation of PhoX, the major alkaline phosphatase protein from the soil bacterium Sinorhizobium meliloti. The protein is shown to be a member of a recently identified family of PhoX alkaline phosphatase proteins ..
  40. Haag A, Wehmeier S, Beck S, Marlow V, Fletcher V, James E, et al. The Sinorhizobium meliloti LpxXL and AcpXL proteins play important roles in bacteroid development within alfalfa. J Bacteriol. 2009;191:4681-6 pubmed publisher
    Free-living Sinorhizobium meliloti lpxXL and acpXL mutants lack lipid A very-long-chain fatty acids (VLCFAs) and have reduced competitiveness in alfalfa...
  41. Bastiat B, Sauviac L, Bruand C. Dual control of Sinorhizobium meliloti RpoE2 sigma factor activity by two PhyR-type two-component response regulators. J Bacteriol. 2010;192:2255-65 pubmed publisher
    RpoE2 is an extracytoplasmic function (ECF) sigma factor involved in the general stress response of Sinorhizobium meliloti, the nitrogen-fixing symbiont of the legume plant alfalfa...
  42. Carlyon R, Ryther J, VanYperen R, Griffitts J. FeuN, a novel modulator of two-component signalling identified in Sinorhizobium meliloti. Mol Microbiol. 2010;77:170-82 pubmed publisher
    b>Sinorhizobium meliloti is a nitrogen-fixing bacterial symbiont of alfalfa and related legumes. Symbiotic infection by S...
  43. Stiens M, Schneiker S, Pühler A, Schluter A. Sequence analysis of the 181-kb accessory plasmid pSmeSM11b, isolated from a dominant Sinorhizobium meliloti strain identified during a long-term field release experiment. FEMS Microbiol Lett. 2007;271:297-309 pubmed
    The 181 251 bp accessory plasmid pSmeSM11b of Sinorhizobium meliloti strain SM11, belonging to a dominant indigenous S. meliloti subpopulation identified during a long-term field release experiment, was sequenced...
  44. Humann J, Schroeder B, Mortimer M, House B, Yurgel S, Maloney S, et al. Construction and expression of sugar kinase transcriptional gene fusions by using the Sinorhizobium meliloti ORFeome. Appl Environ Microbiol. 2008;74:6756-65 pubmed publisher
    The Sinorhizobium meliloti ORFeome project cloned 6,314 open reading frames (ORFs) into a modified Gateway entry vector system from which the ORFs could be transferred to destination vectors in vivo via bacterial conjugation...
  45. Patankar A, GONZALEZ J. An orphan LuxR homolog of Sinorhizobium meliloti affects stress adaptation and competition for nodulation. Appl Environ Microbiol. 2009;75:946-55 pubmed publisher
    The Sin/ExpR quorum-sensing system of Sinorhizobium meliloti plays an important role in the symbiotic association with its host plant, Medicago sativa...
  46. Epstein B, Branca A, Mudge J, Bharti A, Briskine R, Farmer A, et al. Population genomics of the facultatively mutualistic bacteria Sinorhizobium meliloti and S. medicae. PLoS Genet. 2012;8:e1002868 pubmed publisher
    ..Based upon available functional information, several genes identified as targets of selection are likely to alter the symbiosis with the host plant, making them attractive targets for further functional characterization...
  47. Naya L, Ladrera R, Ramos J, Gonzalez E, Arrese Igor C, Minchin F, et al. The response of carbon metabolism and antioxidant defenses of alfalfa nodules to drought stress and to the subsequent recovery of plants. Plant Physiol. 2007;144:1104-14 pubmed
    ..We conclude that a limitation in metabolic capacity of bacteroids and oxidative damage of cellular components are contributing factors to the inhibition of N(2)ase activity in alfalfa nodules. ..
  48. Sevin E, Barloy Hubler F. RASTA-Bacteria: a web-based tool for identifying toxin-antitoxin loci in prokaryotes. Genome Biol. 2007;8:R155 pubmed
    ..The tool successfully confirmed all reported TA systems, and spotted new putative loci upon screening of sequenced genomes. RASTA-Bacteria is publicly available at http://genoweb.univ-rennes1.fr/duals/RASTA-Bacteria. ..
  49. Hoang H, Gurich N, GONZALEZ J. Regulation of motility by the ExpR/Sin quorum-sensing system in Sinorhizobium meliloti. J Bacteriol. 2008;190:861-71 pubmed
    A successful symbiotic relationship between Sinorhizobium meliloti and its host Medicago sativa (alfalfa) depends on several signaling mechanisms, such as the biosynthesis of exopolysaccharides (EPS) by S. meliloti...
  50. Fujishige N, Lum M, De Hoff P, Whitelegge J, Faull K, Hirsch A. Rhizobium common nod genes are required for biofilm formation. Mol Microbiol. 2008;67:504-15 pubmed
    ..oligomer, are also required for the establishment of the three-dimensional architecture of the biofilm of Sinorhizobium meliloti. Common nod gene mutants form a biofilm that is a monolayer. Moreover, adding Nod Factor antibody to S...
  51. Marlow V, Haag A, Kobayashi H, Fletcher V, Scocchi M, Walker G, et al. Essential role for the BacA protein in the uptake of a truncated eukaryotic peptide in Sinorhizobium meliloti. J Bacteriol. 2009;191:1519-27 pubmed publisher
    The inner membrane BacA protein is essential for the establishment of chronic intracellular infections by Sinorhizobium meliloti and Brucella abortus within plant and mammalian hosts, respectively. In their free-living state, S...
  52. Koziol U, Hannibal L, Rodr guez M, Fabiano E, Kahn M, Noya F. Deletion of citrate synthase restores growth of Sinorhizobium meliloti 1021 aconitase mutants. J Bacteriol. 2009;191:7581-6 pubmed publisher
    The symbiotic nitrogen-fixing bacterium Sinorhizobium meliloti 1021 encodes only one predicted aconitase (AcnA) in its genome...
  53. Maunoury N, Redondo Nieto M, Bourcy M, Van de Velde W, Alunni B, Laporte P, et al. Differentiation of symbiotic cells and endosymbionts in Medicago truncatula nodulation are coupled to two transcriptome-switches. PLoS ONE. 2010;5:e9519 pubmed publisher
    The legume plant Medicago truncatula establishes a symbiosis with the nitrogen-fixing bacterium Sinorhizobium meliloti which takes place in root nodules...
  54. Trabelsi D, Pini F, Aouani M, Bazzicalupo M, Mengoni A. Development of real-time PCR assay for detection and quantification of Sinorhizobium meliloti in soil and plant tissue. Lett Appl Microbiol. 2009;48:355-61 pubmed publisher
    b>Sinorhizobium meliloti is a nitrogen-fixing alpha-proteobacterium present in soil and symbiotically associated with root nodules of leguminous plants...
  55. McIntosh M, Meyer S, Becker A. Novel Sinorhizobium meliloti quorum sensing positive and negative regulatory feedback mechanisms respond to phosphate availability. Mol Microbiol. 2009;74:1238-56 pubmed publisher
    The Sin quorum sensing system of Sinorhizobium meliloti depends upon at least three genes, sinR, sinI and expR, and N-acyl homoserine lactones (AHLs) as signals to regulate multiple processes in its free-living state in the rhizosphere ..
  56. Wehmeier S, Arnold M, Marlow V, Aouida M, Myka K, Fletcher V, et al. Internalization of a thiazole-modified peptide in Sinorhizobium meliloti occurs by BacA-dependent and -independent mechanisms. Microbiology. 2010;156:2702-13 pubmed publisher
    BacA proteins play key roles in the chronic intracellular infections of Sinorhizobium meliloti, Brucella abortus and Mycobacterium tuberculosis within their respective hosts. S. meliloti, B. abortus and M...
  57. Valverde C, Livny J, Schlüter J, Reinkensmeier J, Becker A, Parisi G. Prediction of Sinorhizobium meliloti sRNA genes and experimental detection in strain 2011. BMC Genomics. 2008;9:416 pubmed publisher
    ..In addition, we have developed a computational method that proved useful to predict sRNA-encoding genes in S. meliloti. We anticipate that this predictive approach can be flexibly implemented in many other bacterial species. ..
  58. Yurgel S, Kahn M. A mutant GlnD nitrogen sensor protein leads to a nitrogen-fixing but ineffective Sinorhizobium meliloti symbiosis with alfalfa. Proc Natl Acad Sci U S A. 2008;105:18958-63 pubmed publisher
    ..In the symbiosis between Sinorhizobium meliloti and alfalfa, mutations in GlnD, the major bacterial nitrogen stress response sensor protein, led to a ..
  59. Wang C, Kemp J, da Fonseca I, Equi R, Sheng X, Charles T, et al. Sinorhizobium meliloti 1021 loss-of-function deletion mutation in chvI and its phenotypic characteristics. Mol Plant Microbe Interact. 2010;23:153-60 pubmed publisher
    ..In Sinorhizobium meliloti, the TCS ExoS/ChvI controls exopolysaccharide succinoglycan production and flagellum biosynthesis...
  60. Keating D. The Sinorhizobium meliloti ExoR protein is required for the downregulation of lpsS transcription and succinoglycan biosynthesis in response to divalent cations. FEMS Microbiol Lett. 2007;267:23-9 pubmed publisher
    The Sinorhizobium meliloti lpsS gene encodes a sulfotransferase that modifies lipopolysaccharide...
  61. Davies B, Walker G. A highly conserved protein of unknown function is required by Sinorhizobium meliloti for symbiosis and environmental stress protection. J Bacteriol. 2008;190:1118-23 pubmed publisher
    We report here the first characterization of the Sinorhizobium meliloti open reading frame SMc01113. The SMc01113 protein is a member of a highly conserved protein family, universal among bacteria...
  62. Jones K, Kobayashi H, Davies B, Taga M, Walker G. How rhizobial symbionts invade plants: the Sinorhizobium-Medicago model. Nat Rev Microbiol. 2007;5:619-33 pubmed
    ..we review recent discoveries about the mutual recognition process that allows the model rhizobial symbiont Sinorhizobium meliloti to invade and differentiate inside its host plant alfalfa (Medicago sativa) and the model host plant ..
  63. Del Villar M, Rivas R, Peix A, Mateos P, Martínez Molina E, van Berkum P, et al. Stable low molecular weight RNA profiling showed variations within Sinorhizobium meliloti and Sinorhizobium medicae nodulating different legumes from the alfalfa cross-inoculation group. FEMS Microbiol Lett. 2008;282:273-81 pubmed publisher
    ..of each LMW RNA profile it was evident that isolates with LMW RNA profiles I and II belonged to Sinorhizobium meliloti and those displaying profiles III and IV to Sinorhizobium medicae...
  64. Flechard M, Fontenelle C, Blanco C, Goude R, Ermel G, Trautwetter A. RpoE2 of Sinorhizobium meliloti is necessary for trehalose synthesis and growth in hyperosmotic media. Microbiology. 2010;156:1708-18 pubmed publisher
    ..In this study, we show the importance of the alternative sigma factor RpoE2 in Sinorhizobium meliloti osmoadaptation. Construction and characterization of an S...
  65. Jacob A, Adham S, Capstick D, Clark S, Spence T, Charles T. Mutational analysis of the Sinorhizobium meliloti short-chain dehydrogenase/reductase family reveals substantial contribution to symbiosis and catabolic diversity. Mol Plant Microbe Interact. 2008;21:979-87 pubmed publisher
    ..study, we carried out a large-scale mutagenesis of the SDR gene family in the alfalfa root nodule symbiont Sinorhizobium meliloti. Subsequent phenotypic analysis revealed phenotypes for mutants of 21 of the SDR-encoding genes...
  66. Pickering B, Oresnik I. Formate-dependent autotrophic growth in Sinorhizobium meliloti. J Bacteriol. 2008;190:6409-18 pubmed publisher
    ..Taken together, the data allow us to present a model of how S. meliloti can grow on defined medium containing only formate and bicarbonate as carbon sources...
  67. Vernié T, Moreau S, de Billy F, Plet J, Combier J, Rogers C, et al. EFD Is an ERF transcription factor involved in the control of nodule number and differentiation in Medicago truncatula. Plant Cell. 2008;20:2696-713 pubmed publisher
    ..Our work thus reveals a key regulator linking early and late stages of nodulation and suggests that the regulation of the cytokinin pathway is important both for nodule initiation and development...
  68. Chi F, Yang P, Han F, Jing Y, Shen S. Proteomic analysis of rice seedlings infected by Sinorhizobium meliloti 1021. Proteomics. 2010;10:1861-74 pubmed publisher
    ..were applied to analyze the protein profiles of three different tissues (root, leaf sheath and leaf) of Sinorhizobium meliloti 1021 inoculated rice in order to get an understanding about the molecular mechanism...
  69. Kohler P, Zheng J, Schoffers E, Rossbach S. Inositol catabolism, a key pathway in sinorhizobium meliloti for competitive host nodulation. Appl Environ Microbiol. 2010;76:7972-80 pubmed publisher
    The nitrogen-fixing symbiont of alfalfa, Sinorhizobium meliloti, is able to use myo-inositol as the sole carbon source. Putative inositol catabolism genes (iolA and iolRCDEB) have been identified in the S...
  70. Boscari A, Del Giudice J, Ferrarini A, Venturini L, Zaffini A, Delledonne M, et al. Expression dynamics of the Medicago truncatula transcriptome during the symbiotic interaction with Sinorhizobium meliloti: which role for nitric oxide?. Plant Physiol. 2013;161:425-39 pubmed publisher
    ..In particular, depletion of nitric oxide in roots inoculated with Sinorhizobium meliloti greatly increased our understanding of the role of this reactive species in the optimal establishment of ..
  71. Agaras B, Sobrero P, Valverde C. A CsrA/RsmA translational regulator gene encoded in the replication region of a Sinorhizobium meliloti cryptic plasmid complements Pseudomonas fluorescens rsmA/E mutants. Microbiology. 2013;159:230-42 pubmed publisher
    ..sequence was identified in the replication region of plasmid pMBA19a from the alphaproteobacterium Sinorhizobium meliloti. This rsmA-like allele (rsmA(Sm)) is 58 % identical to Xanthomonas axonopodis pv...
  72. Tiricz H, Szucs A, Farkas A, Pap B, Lima R, Maroti G, et al. Antimicrobial nodule-specific cysteine-rich peptides induce membrane depolarization-associated changes in the transcriptome of Sinorhizobium meliloti. Appl Environ Microbiol. 2013;79:6737-46 pubmed publisher
    ..peptides, NCR247 and NCR335, was investigated, and their effect on the transcriptome of the natural target Sinorhizobium meliloti was characterized...
  73. Penterman J, Abo R, De Nisco N, Arnold M, Longhi R, Zanda M, et al. Host plant peptides elicit a transcriptional response to control the Sinorhizobium meliloti cell cycle during symbiosis. Proc Natl Acad Sci U S A. 2014;111:3561-6 pubmed publisher
    The α-proteobacterium Sinorhizobium meliloti establishes a chronic intracellular infection during the symbiosis with its legume hosts. Within specialized host cells, S...
  74. Davies B, Walker G. Identification of novel Sinorhizobium meliloti mutants compromised for oxidative stress protection and symbiosis. J Bacteriol. 2007;189:2110-3 pubmed
    Employing a novel two-part screen, we identified Sinorhizobium meliloti mutants that were both sensitive to hydrogen peroxide and symbiotically defective on the host plant Medicago sativa...
  75. Coque L, Neogi P, Pislariu C, Wilson K, Catalano C, Avadhani M, et al. Transcription of ENOD8 in Medicago truncatula nodules directs ENOD8 esterase to developing and mature symbiosomes. Mol Plant Microbe Interact. 2008;21:404-10 pubmed publisher
    In Medicago truncatula nodules, the soil bacterium Sinorhizobium meliloti reduces atmospheric dinitrogen into nitrogenous compounds that the legume uses for its own growth...
  76. Barra Bily L, Fontenelle C, Jan G, Flechard M, Trautwetter A, Pandey S, et al. Proteomic alterations explain phenotypic changes in Sinorhizobium meliloti lacking the RNA chaperone Hfq. J Bacteriol. 2010;192:1719-29 pubmed publisher
    The ubiquitous bacterial RNA-binding protein Hfq is involved in stress resistance and pathogenicity. In Sinorhizobium meliloti, Hfq is essential for the establishment of symbiosis with Medicago sativa and for nitrogen fixation...
  77. Gao M, Barnett M, Long S, Teplitski M. Role of the Sinorhizobium meliloti global regulator Hfq in gene regulation and symbiosis. Mol Plant Microbe Interact. 2010;23:355-365 pubmed publisher
    ..To begin understanding the role of Hfq in the Sinorhizobium meliloti-Medicago truncatula nitrogen-fixing symbiosis, we defined free-living and symbiotic phenotypes of an hfq ..
  78. Liu W, Chen A, Luo L, Sun J, Cao L, Yu G, et al. Characterization and expression analysis of Medicago truncatula ROP GTPase family during the early stage of symbiosis. J Integr Plant Biol. 2010;52:639-52 pubmed publisher
    ..These results might suggest a role for some ROP GTPases in the regulation of early stages during rhizobial infection in symbiosis...
  79. Pandey S, Minesinger B, Kumar J, Walker G. A highly conserved protein of unknown function in Sinorhizobium meliloti affects sRNA regulation similar to Hfq. Nucleic Acids Res. 2011;39:4691-708 pubmed publisher
    ..Indeed, eliminating SMc01113/YbeY expression in Sinorhizobium meliloti produces symbiotic and physiological phenotypes strikingly similar to those of the hfq mutant...
  80. Sobrero P, Schlüter J, Lanner U, Schlosser A, Becker A, Valverde C. Quantitative proteomic analysis of the Hfq-regulon in Sinorhizobium meliloti 2011. PLoS ONE. 2012;7:e48494 pubmed publisher
    ..In the α-proteobacterium Sinorhizobium meliloti strain 2011, the identification and detection of multiple sRNAs genes and the broadly pleitropic phenotype ..
  81. Couzigou J, Zhukov V, Mondy S, Abu El Heba G, Cosson V, Ellis T, et al. NODULE ROOT and COCHLEATA maintain nodule development and are legume orthologs of Arabidopsis BLADE-ON-PETIOLE genes. Plant Cell. 2012;24:4498-510 pubmed publisher
    ....
  82. Mirabella A, Terwagne M, Zygmunt M, Cloeckaert A, De Bolle X, Letesson J. Brucella melitensis MucR, an orthologue of Sinorhizobium meliloti MucR, is involved in resistance to oxidative, detergent, and saline stresses and cell envelope modifications. J Bacteriol. 2013;195:453-65 pubmed publisher
    Brucella spp. and Sinorhizobium meliloti are alphaproteobacteria that share not only an intracellular lifestyle in their respective hosts, but also a crucial requirement for cell envelope components and their timely regulation for a ..
  83. Bastiat B, Sauviac L, Picheraux C, Rossignol M, Bruand C. Sinorhizobium meliloti sigma factors RpoE1 and RpoE4 are activated in stationary phase in response to sulfite. PLoS ONE. 2012;7:e50768 pubmed publisher
    ..of this work was to better characterize gene regulation in this biologically relevant growth stage in Sinorhizobium meliloti. By a tap-tag/mass spectrometry approach, we identified five sigma factors co-purifying with the RNA ..
  84. Terpolilli J, O Hara G, Tiwari R, Dilworth M, Howieson J. The model legume Medicago truncatula A17 is poorly matched for N2 fixation with the sequenced microsymbiont Sinorhizobium meliloti 1021. New Phytol. 2008;179:62-6 pubmed publisher
    ..is currently being sequenced as a model legume, complementing the sequenced root nodule bacterial strain Sinorhizobium meliloti 1021 (Sm1021). In this study, the effectiveness of the Sm1021-M...
  85. Fournier J, Timmers A, Sieberer B, Jauneau A, Chabaud M, Barker D. Mechanism of infection thread elongation in root hairs of Medicago truncatula and dynamic interplay with associated rhizobial colonization. Plant Physiol. 2008;148:1985-95 pubmed publisher
    ..The concomitant use of fluorescently labeled Sinorhizobium meliloti has further revealed that a bacteria-free zone is frequently present at the growing tip of the IT, thus ..
  86. Babić K, Schauss K, Hai B, Sikora S, Redzepovic S, Radl V, et al. Influence of different Sinorhizobium meliloti inocula on abundance of genes involved in nitrogen transformations in the rhizosphere of alfalfa (Medicago sativa L.). Environ Microbiol. 2008;10:2922-30 pubmed publisher
    ..We investigated the influence of seed inoculation with two indigenous Sinorhizobium meliloti strains exhibiting different efficiency concerning plant growth promotion on nitrogen turnover processes ..
  87. Morris J, GONZALEZ J. The novel genes emmABC are associated with exopolysaccharide production, motility, stress adaptation, and symbiosis in Sinorhizobium meliloti. J Bacteriol. 2009;191:5890-900 pubmed publisher
    The nitrogen-fixing symbiont Sinorhizobium meliloti senses and responds to constantly changing environmental conditions as it makes its way through the soil in search of its leguminous plant host, Medicago sativa (alfalfa)...