african traditional medicine

Summary

Summary: A system of traditional medicine which is based on the beliefs and practices of the African peoples. It includes treatment by medicinal plants and other materia medica as well as by the ministrations of diviners, medicine men, witch doctors, and sorcerers.

Top Publications

  1. ncbi In vitro antiplasmodial activity and cytotoxicity of ethnobotanically selected South African plants
    E A Prozesky
    Department of Botany, University of Pretoria, Pretoria 2002, South Africa
    J Ethnopharmacol 76:239-45. 2001
  2. ncbi Ethnobotanical study of knowledge and medicinal plants use by the people in Dek Island in Ethiopia
    Tilahun Teklehaymanot
    Endod and Other Medicinal Plants Unit, Aklilu Lemma Institute of Pathobiology, Addis Ababa University, P O Box 1176, Addis Ababa, Ethiopia
    J Ethnopharmacol 124:69-78. 2009
  3. ncbi Anthelmintic activities of three medicinal plants from Nigeria
    A A Gbolade
    Department of Pharmacognosy, Faculty of Pharmacy, Olabisi Onabanjo University, Sagamu Campus, Ogun State, Nigeria
    Fitoterapia 79:223-5. 2008
  4. ncbi Ethnobotanical survey of Akwa Ibom State of Nigeria
    Kola K Ajibesin
    Department of Pharmacognosy and Natural Medicine, Faculty of Pharmacy, University of Uyo, Akwa Ibom, Nigeria
    J Ethnopharmacol 115:387-408. 2008
  5. pmc Plant use of the Maasai of Sekenani Valley, Maasai Mara, Kenya
    Rainer W Bussmann
    University of Hawaii, Lyon Arboretum, 3860 Manoa Rd, Honolulu, HI 96822, USA
    J Ethnobiol Ethnomed 2:22. 2006
  6. pmc Ethnobotanical study of medicinal plants used by people in Zegie Peninsula, Northwestern Ethiopia
    Tilahun Teklehaymanot
    Endod and Other Medicinal Plants Unit, Aklilu Lemma Institute of Pathobiology, Addis Ababa University, PO Box 1176, Addis Ababa, Ethiopia
    J Ethnobiol Ethnomed 3:12. 2007
  7. ncbi Ethnoveterinary medicinal plants at Bale Mountains National Park, Ethiopia
    Haile Yineger
    Department of Biology, Jimma University, P O Box 5195, Jimma, Ethiopia
    J Ethnopharmacol 112:55-70. 2007
  8. pmc Care-seeking patterns for fatal malaria in Tanzania
    Don de Savigny
    Tanzania Essential Health Interventions Project, P O Box 78487, Dar es Salaam, Tanzania
    Malar J 3:27. 2004
  9. ncbi Medicinal plants of the Shinasha, Agew-awi and Amhara peoples in northwest Ethiopia
    Mirutse Giday
    Aklilu Lemma Institute of Pathobiology, P O Box 1176, Addis Ababa University, Addis Ababa, Ethiopia
    J Ethnopharmacol 110:516-25. 2007
  10. ncbi Antibacterial, anti-inflammatory, anti-cholinesterase and mutagenic effects of extracts obtained from some trees used in South African traditional medicine
    I M S Eldeen
    Research Centre for Plant Growth and Development, School of Biological and Conservation Sciences, University of KwaZulu Natal Pietermaritzburg, Scottsville, South Africa
    J Ethnopharmacol 102:457-64. 2005

Research Grants

Detail Information

Publications197 found, 100 shown here

  1. ncbi In vitro antiplasmodial activity and cytotoxicity of ethnobotanically selected South African plants
    E A Prozesky
    Department of Botany, University of Pretoria, Pretoria 2002, South Africa
    J Ethnopharmacol 76:239-45. 2001
    ..Chloroquine had an IC(50) of 0.043 microg/ml. Cytotoxicities of the five most active extracts at 50 microg/ml were determined with the monkey kidney cell toxicity test and the ID(50) values ranged between 35 and 100 microg/ml...
  2. ncbi Ethnobotanical study of knowledge and medicinal plants use by the people in Dek Island in Ethiopia
    Tilahun Teklehaymanot
    Endod and Other Medicinal Plants Unit, Aklilu Lemma Institute of Pathobiology, Addis Ababa University, P O Box 1176, Addis Ababa, Ethiopia
    J Ethnopharmacol 124:69-78. 2009
    ..It reveals the trend of knowledge of medicinal plants and the documentation serves as a baseline data for future phytochemical and pharmacological studies...
  3. ncbi Anthelmintic activities of three medicinal plants from Nigeria
    A A Gbolade
    Department of Pharmacognosy, Faculty of Pharmacy, Olabisi Onabanjo University, Sagamu Campus, Ogun State, Nigeria
    Fitoterapia 79:223-5. 2008
    ..mombin which exhibited comparatively higher efficacy (34-44 min paralysis time and 105 min death time for the leaf) at lower concentrations of 10-20 mg/ml were adjudged the outstanding anthelmintics of plant origin accordingly...
  4. ncbi Ethnobotanical survey of Akwa Ibom State of Nigeria
    Kola K Ajibesin
    Department of Pharmacognosy and Natural Medicine, Faculty of Pharmacy, University of Uyo, Akwa Ibom, Nigeria
    J Ethnopharmacol 115:387-408. 2008
    ..The medicinal plants employed in the ethnomedicine of Akwa Ibom State of Nigeria are studied...
  5. pmc Plant use of the Maasai of Sekenani Valley, Maasai Mara, Kenya
    Rainer W Bussmann
    University of Hawaii, Lyon Arboretum, 3860 Manoa Rd, Honolulu, HI 96822, USA
    J Ethnobiol Ethnomed 2:22. 2006
    ..In most cases the treatment of illness involves herbal purgatives to cleanse the patient. There are also frequent indications of plant use for common problems like wounds, parasites, body aches and burns...
  6. pmc Ethnobotanical study of medicinal plants used by people in Zegie Peninsula, Northwestern Ethiopia
    Tilahun Teklehaymanot
    Endod and Other Medicinal Plants Unit, Aklilu Lemma Institute of Pathobiology, Addis Ababa University, PO Box 1176, Addis Ababa, Ethiopia
    J Ethnobiol Ethnomed 3:12. 2007
    ....
  7. ncbi Ethnoveterinary medicinal plants at Bale Mountains National Park, Ethiopia
    Haile Yineger
    Department of Biology, Jimma University, P O Box 5195, Jimma, Ethiopia
    J Ethnopharmacol 112:55-70. 2007
    ..76%) followed by dermal (55 species, 36.18%). Indigenous knowledge was mostly transferred to an elect of a family member in word of mouth indicating that it was prone to fragmentation or loss...
  8. pmc Care-seeking patterns for fatal malaria in Tanzania
    Don de Savigny
    Tanzania Essential Health Interventions Project, P O Box 78487, Dar es Salaam, Tanzania
    Malar J 3:27. 2004
    ..Although patterns of care-seeking during uncomplicated malaria episodes are well known, studies in cases of fatal malaria are rare. Care-seeking behaviours may differ between these groups...
  9. ncbi Medicinal plants of the Shinasha, Agew-awi and Amhara peoples in northwest Ethiopia
    Mirutse Giday
    Aklilu Lemma Institute of Pathobiology, P O Box 1176, Addis Ababa University, Addis Ababa, Ethiopia
    J Ethnopharmacol 110:516-25. 2007
    ..Measures are needed to conserve plants that are reported as scarce in the study area but still are only harvested from the wild...
  10. ncbi Antibacterial, anti-inflammatory, anti-cholinesterase and mutagenic effects of extracts obtained from some trees used in South African traditional medicine
    I M S Eldeen
    Research Centre for Plant Growth and Development, School of Biological and Conservation Sciences, University of KwaZulu Natal Pietermaritzburg, Scottsville, South Africa
    J Ethnopharmacol 102:457-64. 2005
    Extracts obtained from 10 trees used in South African traditional medicine were screened for antibacterial, anti-inflammatory (COX-1 and COX-2) and anti-cholinesterase activities and investigated for potential mutagenic effects using the ..
  11. ncbi Medical syncretism with reference to malaria in a Tanzanian community
    Susanna Hausmann Muela
    Swiss Tropical Institute, Department of Public Health and Epidemiology, Basel
    Soc Sci Med 55:403-13. 2002
    ..Disentangling syncretic processes permits us to understand the dynamics of how information is processed by the recipients, and provides orientations for health promoters for adapting messages to the local context...
  12. ncbi Recognizing childhood illnesses and their traditional explanations: exploring options for care-seeking interventions in the context of the IMCI strategy in rural Ghana
    Zelee Hill
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
    Trop Med Int Health 8:668-76. 2003
    ..This paper explores the relative importance of illness recognition as a barrier to care-seeking and the feasibility and potential impact of improving recognition...
  13. ncbi Use of traditional medicine by HIV-infected individuals in South Africa in the era of antiretroviral therapy
    Dale A Babb
    Clinical Research Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    Psychol Health Med 12:314-20. 2007
    ..Concomitant use with ART has the potential for drug interactions and should be discussed routinely in ART counselling. Further work is warranted to investigate whether commonly used traditional medicines interact with ART in vivo...
  14. ncbi Local understanding, perceptions and reported practices of mothers/guardians and health workers on childhood malaria in a Tanzanian district--implications for malaria control
    C Comoro
    Department of Sociology, University of Dar es Salaam, Dar es Salaam, Tanzania
    Acta Trop 87:305-13. 2003
    ..Our findings revealed major gaps in managing severe malaria in the study communities. Interventions addressing these gaps and targeting mothers/guardians, mother in-laws, grandmothers and traditional healers are needed...
  15. ncbi Traditional medicine in north Côte-d'Ivoire: screening of 50 medicinal plants for antibacterial activity
    W M Koné
    Laboratoire de Botanique, UFR Biosciences, Universite de Cocody, Abidjan, Cote d Ivoire
    J Ethnopharmacol 93:43-9. 2004
    ..The results provided evidence that some of the studied plants might indeed be potential sources of new antibacterial agents, also against some antibiotic-resistant strains...
  16. ncbi Ethnopharmacological survey of plants used for the treatment of schistosomiasis in Niono District, Mali
    Sekou Bah
    Department of Pharmaceutical Chemistry, School of Pharmacy, University of Oslo, P O Box 1068 Blindern, N 0316 Oslo, Norway
    J Ethnopharmacol 105:387-99. 2006
    ..Cissus quadrangularis and Stylosanthes erecta were the plants most frequently used and were reported for the first time, to be used against schistosomiasis in Mali...
  17. ncbi Antiviral activity against human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) of ethnobotanically selected Ethiopian medicinal plants
    K Asres
    Department of Pharmacognosy, School of Pharmacy, Addis Ababa University, Addis Ababa, Ethiopia
    Phytother Res 15:62-9. 2001
    ..The results obtained in this study enable the selection of extracts which show some specificity of action and support the further investigation of these extracts for their potential as new lead antiretroviral compounds...
  18. ncbi An ethnobotanical study of medicinal plants used by the Zay people in Ethiopia
    Mirutse Giday
    Institute of Pathobiology, Addis Ababa University, P O Box 12577, Ethiopia
    J Ethnopharmacol 85:43-52. 2003
    ..Measures for conservation of medicinal plants of the Zay people are urgently needed...
  19. ncbi Ethnobotanical studies and economic evaluation of medicinal plants in Taounate province (Northern Morocco)
    Jaouad El-Hilaly
    UFR Physiology Pharmacology, Laboratory of Animal Physiology, Department of Biology, Faculty of Sciences, Dhar El Mehraz, USMBA, BP 1976 Atlas Fez, Morocco
    J Ethnopharmacol 86:149-58. 2003
    ..This survey demonstrates that the medicinal plant sector in the province is a promising economic resource for developing this region, but it needs planned exploitation, and that the tribes should continue to master the folk-medicine...
  20. ncbi Traditional herbal drugs of Bulamogi, Uganda: plants, use and administration
    J R S Tabuti
    Department of Biology and Nature Conservation, Agricultural University of Norway, P O Box 5014, N 1432 As, Norway
    J Ethnopharmacol 88:19-44. 2003
    ..The processing, packaging and storage of herbal medicines is substandard and require improvement...
  21. pmc Recognition, perceptions and treatment practices for severe malaria in rural Tanzania: implications for accessing rectal artesunate as a pre-referral
    Marian Warsame
    Division of International Health IHCAR, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 2:e149. 2007
    ....
  22. pmc Traditional medicinal plant knowledge and use by local healers in Sekoru District, Jimma Zone, Southwestern Ethiopia
    Haile Yineger
    Department of Biology, Jimma University, P, O, Box 5195, Jimma, Ethiopia
    J Ethnobiol Ethnomed 3:24. 2007
    ..Plant parts used for remedy preparations showed significant difference with medicinal plant species abundance in the study area...
  23. pmc Use of traditional medicines in the management of HIV/AIDS opportunistic infections in Tanzania: a case in the Bukoba rural district
    Daniel P Kisangau
    Department of Botany, University of Dar es Salaam, Dar es Salaam, Tanzania
    J Ethnobiol Ethnomed 3:29. 2007
    ..Other symptomatic but undefined conditions considered were skin rashes and chronic diarrhea...
  24. ncbi Polysaccharides with complement fixing and macrophage stimulation activity from Opilia celtidifolia, isolation and partial characterisation
    Adiaratou Togola
    Section of Pharmacognosy, Department of Pharmaceutical Chemistry, University of Oslo, P O Box 1068, Blindern, N 0316 Oslo, Norway
    J Ethnopharmacol 115:423-31. 2008
    ..The present study is aimed to determine the bioactivity and structure of polysaccharides present in the leaves from the Malian medicinal plant Opilia celtidifolia [Guill. & Perr. Endl. ex Walp (Opiliaceae)]...
  25. ncbi Brine shrimp toxicity of some plants used as traditional medicines in Kagera Region, north western Tanzania
    M J Moshi
    Department of Biological and Preclinical Studies, Institute of Traditional Medicine, Muhimbili University of Health and Allied Sciences, Box 65001, Dar es Salaam, Tanzania
    Tanzan J Health Res 12:63-7. 2010
    ..Picralima nitida and Rubus rigidus extracts are mildly toxic, but by comparison have a remote possibility to yield active anticancer compounds...
  26. pmc Role of traditional healers in the management of severe malaria among children below five years of age: the case of Kilosa and Handeni Districts, Tanzania
    Emmanuel A Makundi
    National Institute for Medical Research NIMR, P O Box 9653 Dar es Salaam, Tanzania
    Malar J 5:58. 2006
    ..In the context of the Rectal Artesunate Project in Tanzania, the role of traditional healers in the management of severe malaria in children was studied...
  27. pmc Kenyan medicinal plants used as antivenin: a comparison of plant usage
    Bethwell O Owuor
    The Catholic University of Eastern Africa, Department of Natural Sciences, P, O, Box 62157, Nairobi, Kenya
    J Ethnobiol Ethnomed 2:7. 2006
    ..A high degree of informant consensus for the species was observed. The study indicates rural Kenya inhabitants rely on medicinal plants for healthcare...
  28. ncbi Ethnobotanical study of some Ghanaian anti-malarial plants
    Alex Asase
    Department of Botany, University of Ghana, P O Box LG 55 Legon, Ghana
    J Ethnopharmacol 99:273-9. 2005
    ..The results are discussed and recommendations made for future research to support the conservation and sustainable harvesting of the species reported to have medicinal properties...
  29. ncbi Treatment of childhood fevers and other illnesses in three rural Nigerian communities
    L A Salako
    Nigerian Institute of Medical Research and Training, Yaba, Lagos
    J Trop Pediatr 47:230-8. 2001
    ....
  30. ncbi Antiplasmodial activity and cytotoxicity of plants used in West African traditional medicine for the treatment of malaria
    Herve Menan
    Laboratoire d Immunologie et Parasitologie, EA 2413, UFR des Sciences Pharmaceutiques et Biologiques, 15, Av Ch Flahault, BP 14491, 34093 Montpellier cedex 2, France
    J Ethnopharmacol 105:131-6. 2006
    ..The pentane extracts of Cola caricaefolia and Uvaria afzelii, which revealed the strongest antiplasmodial activity had CAR values of about 10...
  31. ncbi Use of traditional medicine among pregnant women in Lusaka, Zambia
    Yolan Banda
    University of Zambia School of Medicine, Lusaka, Zambia
    J Altern Complement Med 13:123-7. 2007
    ..We studied the prevalence of and predictors for traditional medicine use among pregnant women seeking care in the Lusaka, Zambia public health system...
  32. ncbi Herbal medicines used in the treatment of malaria in Budiope county, Uganda
    John R S Tabuti
    Department of Botany, Makerere University, P O Box 7062, Kampala, Uganda
    J Ethnopharmacol 116:33-42. 2008
    ..This study was conducted to document herbal medicines (HMs) used in the treatment of malaria as well as the existing knowledge, attitudes and practices related to malaria recognition, control and treatment in Budiope county, Uganda...
  33. ncbi Further evaluation of Rwandan medicinal plant extracts for their antimicrobial and antiviral activities
    P Cos
    Faculty of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, B 2610 Antwerp, Belgium
    J Ethnopharmacol 79:155-63. 2002
    ..Some plant extracts showed an antibacterial activity against Gram-positive bacteria and Mycobacterium fortuitum, but none of them were active against the Gram-negative bacteria tested...
  34. ncbi An ethnobotanical study of plants used for the treatment of sexually transmitted diseases (njovhera) in Guruve District, Zimbabwe
    L Kambizi
    Department of Botany, University of Fort Hare, Alice 5700, South Africa
    J Ethnopharmacol 77:5-9. 2001
    ..Generally the water extracts show less activity than acetone and methanol extracts...
  35. ncbi African traditional healers: what health care professionals need to know
    Threethambal Puckree
    Department of Physiotherapy, University of Durban Westville, Durban, South Africa
    Int J Rehabil Res 25:247-51. 2002
    ..We conclude that traditional healing is an integral component of health care in South Africa. Health care professionals need to be proactive in integrating traditional healing with Westernized practices to promote health for all...
  36. ncbi Ethnobotanical study of medicinal plants around 'Dheeraa' town, Arsi Zone, Ethiopia
    Tigist Wondimu
    Department of Biology, Faculty of Science, Addis Ababa University, P O Box 3434, Addis Ababa, Ethiopia
    J Ethnopharmacol 112:152-61. 2007
    ..Paying special attention to the medicinal plants found in the area may help to amplify the role that these plants play in healthcare, poverty alleviation as well as environmental protection...
  37. ncbi Traditional African medicine in the treatment of HIV
    Edward Mills
    Lancet Infect Dis 5:465-7. 2005
  38. ncbi Antimicrobial activities of some selected traditional Ethiopian medicinal plants used in the treatment of skin disorders
    Hailu Tadeg
    Department of Pharamceutics, School of Pharmacy, Addis Ababa University, P O Box 1176, Ethiopia
    J Ethnopharmacol 100:168-75. 2005
    ..The results indicate the potential of these herbal drugs in treating microbial infections of the skin, thus, justifying their claimed uses in the treatment of various skin disorders, the majority of which are of infectious origin...
  39. pmc Malaria in pregnancy: what can the social sciences contribute?
    Joan Muela Ribera
    Universitat Autonoma de Barcelona, Departament d Antropología Social, Barcelona, Spain
    PLoS Med 4:e92. 2007
  40. pmc Cardiovascular effects of mollic acid glucoside, a 1alpha-hydroxycycloartenoid saponin extractive from Combretum molle R Br ex G Don (Combretaceae) leaf
    J A Ojewole
    Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu Natal, Durban, South Africa
    Cardiovasc J Afr 19:128-34. 2008
    ..The findings of this study suggest that Combretum molle leaf may be used as a natural supplementary remedy in essential hypertension and in certain cases of cardiac dysfunctions in rural African communities...
  41. ncbi Medicinal plants used to induce labour during childbirth in western Uganda
    Maud Kamatenesi-Mugisha
    Department of Botany, Makerere University, P O Box 7062, Kampala, Uganda
    J Ethnopharmacol 109:1-9. 2007
    ....
  42. ncbi Traditional healers in Nigeria: perception of cause, treatment and referral practices for severe malaria
    T A Okeke
    Department of Community Medicine, College of Medicine, University of Nigeria, Enugu, Nigeria
    J Biosoc Sci 38:491-500. 2006
    ..The fact that traditional healers are important providers of treatment for severe malaria, especially convulsions, underlines the need to enlist their support in efforts to improve referral practices for severe malaria...
  43. ncbi Caring for people with HIV in Zambia: are traditional healers and formal health workers willing to work together?
    A Burnett
    Department of General Practice, St Bartholomew s and the Royal London Hospital Medical College, UK
    AIDS Care 11:481-91. 1999
    ..Involving traditional healers in supplying condoms may improve acceptability and availability, particularly in rural areas...
  44. ncbi Medicinal plants used for intestinal diseases in Mbalmayo region, Central Province, Cameroon
    E Noumi
    Laboratoire de Biologie végétale, Ecole Normale Superieure, Université de Yaoundé 1, BP 47, Yaounde, Cameroon
    Fitoterapia 72:246-54. 2001
    ..Seventy-six plant species from 46 botanical families, traditionally used to treat intestinal diseases in Mbalmayo region are recorded. The local names and the way the plants are used are indicated...
  45. pmc Potentials of leaves of Aspilia africana (Compositae) in wound care: an experimental evaluation
    C O Okoli
    Department of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Enugu State, Nigeria
    BMC Complement Altern Med 7:24. 2007
    ..The present study was undertaken to evaluate the potentials for use of leaves of this plant in wound care...
  46. ncbi Antimicrobial and brine shrimp toxicity of some plants used in traditional medicine in Bukoba District, north-western Tanzania
    M J Moshi
    Department of Biological and Preclinical Studies, Institute of Traditional Medicine, Muhimbili University of Health and Allied Sciences, P O Box 65001, Dar es Salaam, Tanzania
    Tanzan J Health Res 11:23-8. 2009
    ..The seemingly innocuous nature and relatively good antibacterial activity against skin infections and gastrointestinal pathogenic bacteria support the traditional uses of the plants and deserve more detailed studies...
  47. pmc Malaria in rural Burkina Faso: local illness concepts, patterns of traditional treatment and influence on health-seeking behaviour
    Claudia Beiersmann
    Department of Tropical Hygiene and Public Health, Medical School, Ruprecht Karls Universitat Heidelberg, INF 324, Heidelberg, Germany
    Malar J 6:106. 2007
    ..Understanding local concepts of illness and their influence on health care-seeking behaviour can complement existing knowledge and lead to the development of more effective malaria control interventions...
  48. ncbi Ethnobotanical survey and antibacterial activity of some plants used in Guinean traditional medicine
    F B Magassouba
    Centre de Recherche et de Valorisation des Plantes Médicinales de Dubréka, BP 6411 Conakry, Guinea
    J Ethnopharmacol 114:44-53. 2007
    ....
  49. ncbi Medicinal plant diversity and uses in the Sango bay area, Southern Uganda
    Paul Ssegawa
    Department of Botany, Makerere University, Kampala, Uganda
    J Ethnopharmacol 113:521-40. 2007
    ..Suggestions for future conservation programs, sustainable utilization and ethnopharmacological studies are given...
  50. ncbi Antibacterial activity of Harungana madagascariensis leaf extracts
    A S Okoli
    Department of Microbiology, University of Nigeria, Nsukka, Enugu State, Nigeria
    Phytother Res 16:174-9. 2002
    ..The results provide a rationalization for the traditional use of H. madagascariensis leaf extracts for the treatment of gastrointestinal disorders...
  51. ncbi Use of traditional herbal medicine by AIDS patients in Kabarole District, western Uganda
    Deanne Langlois-Klassen
    Department of Public Health Sciences, School of Public Health, University of Alberta, Edmonton, Canada
    Am J Trop Med Hyg 77:757-63. 2007
    ..The primary conclusion is that AIDS outpatients commonly use herbal medicine for the treatment of HIV/AIDS. Pharmacological interactions between antiretroviral drugs and traditional herbal medicines need to be further examined...
  52. ncbi Anti-plasmodial activity of some Kenyan medicinal plant extracts singly and in combination with chloroquine
    F W Muregi
    Biochemistry Department, School of Pure and Applied Sciences, Kenyatta University, Nairobi, Kenya
    Phytother Res 18:379-84. 2004
    ..capensis and C. myricoides with chloroquine against the multi-drug resistant P. falciparum isolate (V1/S) revealed synergistic effect. The plants which showed activity may be useful as sources for novel anti-plasmodial compounds...
  53. ncbi Oldenlandia affinis (R&S) DC. A plant containing uteroactive peptides used in African traditional medicine
    L Gran
    Biotechnology Center of Oslo, University of Oslo, P O Box 1125, N 0316, Oslo, Norway
    J Ethnopharmacol 70:197-203. 2000
    ..Some of these peptides, included Kalata-peptide B1, have been shown to hold antimicrobial activity. They have recently been synthesized, and they may represent a starting point for the design of new peptide antibiotics...
  54. ncbi The analgesic effect of the methanolic extract of Acanthus montanus
    Olufunmilayo O Adeyemi
    Department of Pharmacology, College of Medicine, University of Lagos, PMB 12003, Lagos, Nigeria
    J Ethnopharmacol 90:45-8. 2004
    ..The results indicate that the analgesic effect of Acanthus montanus methanolic extract is both centrally and peripherally mediated...
  55. ncbi Knowledge and use of medicinal plants by people around Debre Libanos monastery in Ethiopia
    Tilahun Teklehaymanot
    Aklilu Lemma Institute of Pathobiology, Addis Ababa University, P O Box 1176, Addis Ababa, Ethiopia
    J Ethnopharmacol 111:271-83. 2007
    ..This may result in the long run in loss of local knowledge in the surrounding area and the country at large for preparation of pharmacologically effective remedies...
  56. ncbi The challenges of involving traditional healers in HIV/AIDS care
    E Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Ontario, Canada, and Department of Medicine, University of Calabar Teaching Hospital, Nigeria
    Int J STD AIDS 17:360-3. 2006
    ..Collaboration is essential, given the changing epidemic of HIV and the dynamic relationship between the two health sectors...
  57. ncbi Bioactive constituents of the bark of Parkia biglobosa
    C Tringali
    Dipartimento di Scienze Chimiche, Universita di Catania, Viale A Doria 6, I 95125, Catania, Italy
    Fitoterapia 71:118-25. 2000
    ..In addition, lupeol, 4-O-methyl-epi-gallocatechin, epi-gallocatechin, epi-catechin 3-O-gallate, and epi-gallocatechin 3-O-gallate were isolated...
  58. ncbi Investigating the safety of plants used in South African traditional medicine: testing for genotoxicity in the micronucleus and alkaline comet assays
    Joslyn L S Taylor
    Flemish Institute of Technological Research VITO, Environmental Toxicology, Mol, Belgium
    Environ Mol Mutagen 42:144-54. 2003
    ..Although a number of these plants are recognised as toxic by traditional healers, several plants that are used in common remedies were found to be genotoxic and potentially dangerous. Environ...
  59. ncbi Cross-cultural healing in east African ethnography
    O B Rekdal
    Department of Health and Social Sciences, Bergen College, USA
    Med Anthropol Q 13:458-82. 1999
    ..have been biased in ways that have drawn attention away from what is a prominent feature of African traditional medicine: the search for healing in the culturally distant...
  60. ncbi Defining minimum standards of practice for incorporating African traditional medicine into HIV/AIDS prevention, care, and support: a regional initiative in eastern and southern Africa
    Jaco Homsy
    Traditional and Modern Health Practitioners Together Against AIDS and Other Diseases, Kampala, Uganda
    J Altern Complement Med 10:905-10. 2004
    ..the current pan-African prevention and care efforts spurred by the HIV pandemic do not actively engage African Traditional Medicine, they will effectively miss 80%, the vast majority of the African people who, according to the World ..
  61. ncbi Identification of potent anticancer activity in Ximenia americana aqueous extracts used by African traditional medicine
    Cristina Voss
    Unit of Toxicology and Chemotherapy, Deutsches Krebsforschungszentrum Heidelberg, E100, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Toxicol Appl Pharmacol 211:177-87. 2006
    The antineoplastic activity of a plant powder used in African traditional medicine for treating cancer was investigated by analyzing the activity of various extracts in vitro...
  62. ncbi Herbal medicine in Kenya: evidence of safety and efficacy
    J A Orwa
    East Afr Med J 79:341-2. 2002
  63. ncbi In vitro antiplasmodial activity of some plants used in Kisii, Kenya against malaria and their chloroquine potentiation effects
    F W Muregi
    Biochemistry Department, Kenyatta University, PO Box 43844, Nairobi, Kenya
    J Ethnopharmacol 84:235-9. 2003
    ..falciparum isolate V1/S revealed some synergistic effect. The plant extracts with low IC(50) values may be used as sources for novel antimalarial compounds to be used alone or in combination with CQ...
  64. ncbi The adapting healer: pioneering through shifting epidemiological and sociocultural landscapes
    Heather McMillen
    University of Hawaii, Department of Anthropology, 2424 Maile Way, Honolulu, HI 96822, USA
    Soc Sci Med 59:889-902. 2004
    ..Although the healer featured in this article is a pioneer in his own town, there are other examples in Africa where healers and biomedical practitioners are interacting. Therefore, he may represent a trend in healer adaptation...
  65. ncbi Traditional health practitioners are key to scaling up comprehensive care for HIV/AIDS in sub-Saharan Africa
    Jaco Homsy
    AIDS 18:1723-5. 2004
  66. pmc Western medicine and traditional healers: partners in the fight against HIV/AIDS
    Joan Liverpool
    Morehouse School of Medicine, Department of Pediatrics, 720 Westview Drive SW, Atlanta, GA 30310, USA
    J Natl Med Assoc 96:822-5. 2004
    ..Innovative and effective approaches, including utilization of traditional healers, can play a vital role in Africa's AIDS prevention and control programs...
  67. ncbi Ethical and regulatory issues surrounding African traditional medicine in the context of HIV/AIDS
    Aceme Nyika
    Centre for the AIDS Programme of Research in South Africa CAPRISA, Nelson R Mandela School of Medicine, University of KwaZulu Natal, South Africa
    Dev World Bioeth 7:25-34. 2007
    ..It is hoped that this paper will stimulate objective and constructive debate that could enhance the protection of patients' welfare...
  68. pmc Ethnobotanical survey of trees in Fundong, Northwest Region, Cameroon
    Derek A Focho
    Department of Plant Biology, University of Dschang, Dschang, Cameroon
    J Ethnobiol Ethnomed 5:17. 2009
    ..There is therefore need for cultivation, protection and sustainable management of these valuable resources for rural livelihoods...
  69. ncbi An ethnopharmacological survey of plants used for wound healing in Dogonland, Mali, West Africa
    Kari Inngjerdingen
    Department of Pharmacognosy, School of Pharmacy, University of Oslo, P O Box 1068 Blindern, N 0316 Oslo, Norway
    J Ethnopharmacol 92:233-44. 2004
    ..The most frequently used preparations are decoctions and powdered plant material...
  70. ncbi An assessment of two Carpobrotus species extracts as potential antimicrobial agents
    E P Springfield
    South African Traditional Medicines Research Group, School of Pharmacy, University of the Western Cape, Bellville, South Africa
    Phytomedicine 10:434-9. 2003
    ..This scientific information can serve as an important platform for the development of inexpensive, safe and effective natural anti-infective medicines...
  71. ncbi Antifungal activities of six South African Terminalia species (Combretaceae)
    P Masoko
    Phytomedicine Programme, Department of Paraclinical Sciences, University of Pretoria, Private Bag X04, Onderstepoort, 0110, South Africa
    J Ethnopharmacol 99:301-8. 2005
    ..0.08 mg/ml, some were with MIC values as low as 0.02 mg/ml. Microsporum canis was the most susceptible microorganism and Terminalia sericea extracts were the most active against nearly all microorganisms tested...
  72. ncbi In-vivo antipyretic studies of the aqueous and ethanol extracts of the leaves of Ajuga remota and Lippia adoensis
    Asfaw Debell
    Department of Drug Research, Ethiopian Health and Nutrition Research Institute
    Ethiop Med J 43:111-8. 2005
    ..Most of them, however, have not been subjected to scientific investigation for their efficacy and safety...
  73. ncbi Anabolic effect of Hibiscus rosasinensis Linn. leaf extracts in immature albino male rats
    S O Olagbende-Dada
    Department of Pharmacognosy, Faculty of Pharmacy, College of Medicine, University of Lagos, Idi Araba, Lagos, Nigeria
    Nig Q J Hosp Med 17:5-7. 2007
    ..Cold aqueous extract of Hibiscus rosasinensis leaves is reported by local traditional practioners in Western Nigeria to be aphrodisiac...
  74. ncbi In vitro cytotoxicity studies of 20 plants used in Nigerian antimalarial ethnomedicine
    E O Ajaiyeoba
    Faculty of Pharmacy, Department of Pharmacognosy, University of Ibadan, Ibadan, Nigeria
    Phytomedicine 13:295-8. 2006
    ..1 and 2.6 microg/ml, respectively. The least toxic plant extract was Bridelia micrantha (LC(50) value >9.0 x 10(6) microg/ml). Most of the plants were found to be relatively non-toxic...
  75. ncbi In vitro antidrepanocytary actvity (anti-sickle cell anemia) of some congolese plants
    P T Mpiana
    Departement de Chimie, Universite de Kinshasa, Kinshasa XI, R D Congo
    Phytomedicine 14:192-5. 2007
    ....
  76. ncbi The perception and practice of traditional medicine in the treatment of cancers and inflammations by the Hausa and Fulani tribes of Northern Nigeria
    M S Abubakar
    Pharmacognosy and Drug Development, Ahmadu Bello University Zaria, Nigeria
    J Ethnopharmacol 111:625-9. 2007
    ..The inventory provides the unique opportunity of capturing plants of common uses across the communities...
  77. ncbi Evaluation of anti-diarrhoeal and anti-ulcerogenic potential of ethanol extract of Carpolobia lutea leaves in rodents
    Paul A Nwafor
    Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Uyo, Uyo, Akwa Ibom State, Nigeria
    J Ethnopharmacol 111:619-24. 2007
    ....
  78. ncbi Ethnobotanical studies of medicinal plants used in the management of diabetes mellitus in South Western Nigeria
    K A Abo
    Department of Pharmacognosy, University of Ibadan, Nigeria
    J Ethnopharmacol 115:67-71. 2008
    ..The survey shows plants from the Rutaceae, Leguminosae and Cucurbitaceae families are commonly used by traditional healers in South West Nigeria for the treatment of diabetes mellitus...
  79. ncbi Antibacterial activity of Venda medicinal plants
    Vanessa Steenkamp
    Department of Pharmacology, University of Pretoria, South Africa
    Fitoterapia 78:561-4. 2007
    ..Combretum molle, Peltophorum africanum, Piper capense, Terminalia sericea and Zanthoxylum davyi were the most active and presented MIC values < or =1.00 mg/ml...
  80. ncbi Antiplasmodial and GABA(A)-benzodiazepine receptor binding activities of five plants used in traditional medicine in Mali, West Africa
    Sekou Bah
    University of Oslo, School of Pharmacy, Department of Pharmaceutical Chemistry, PO Box 1068 Blindern, N 0316 Oslo, Norway
    J Ethnopharmacol 110:451-7. 2007
    ..The results in this study justify some of the traditional indications of the plants investigated and may thus be candidates for Improved Traditional Medicines in Mali...
  81. ncbi Diuretic activity of the aqueous extracts of Carum carvi and Tanacetum vulgare in normal rats
    Sanaa Lahlou
    UFR Physiology Pharmacology, Laboratory of Animal Physiology, Department of Biology, Fez, Morocco
    J Ethnopharmacol 110:458-63. 2007
    ....
  82. ncbi Antibacterial activity of plants used in traditional medicines of Ghana with particular reference to MRSA
    George A Pesewu
    School of Health and Bioscience, University of East London, Stratford, London E15 4LZ, UK
    J Ethnopharmacol 116:102-11. 2008
    ....
  83. pmc Bioprospecting the African Renaissance: the new value of muthi in South Africa
    Hanspeter C W Reihling
    Institute for Social Anthropology, Freie Universitat Berlin, Landoltweg 9 11, 14195 Berlin, Germany
    J Ethnobiol Ethnomed 4:9. 2008
    ..In this context, the translation of socially and culturally situated local knowledge about muthi into global pharmaceuticals creates new forms of agency as well as new power differentials between the different actors involved...
  84. ncbi Anti-mycobacterial activity of five plant species used as traditional medicines in the Western Cape Province (South Africa)
    Kapinga Bamuamba
    Department of Molecular and Cell Biology, University of Cape Town, Rondebosch 7701, South Africa
    J Ethnopharmacol 117:385-90. 2008
    ....
  85. ncbi Anti-plasmodial activity and toxicity of extracts of plants used in traditional malaria therapy in Meru and Kilifi Districts of Kenya
    P G Kirira
    Department of Chemistry, School of Pure and Applied Sciences, Kenyatta University, P O Box 43844, Nairobi 00100 GPO, Kenya
    J Ethnopharmacol 106:403-7. 2006
    ..falciparum strains. The results support the use of traditional herbs for anti-malarial therapy and demonstrate their potential as sources of drugs...
  86. ncbi Antimalarial activity of some plants traditionally used in Meru district of Kenya
    C N Muthaura
    Centre for Traditional Medicine and Drug Research, Kenya Medical Research Institute, P O Box 54840, Nairobi 00200, Kenya
    Phytother Res 21:860-7. 2007
    ..05) with no overt signs of toxicity. However, the extracts were cytotoxic (SI, 0.96-2.51) on Vero E6 cells. These results suggest that there is potential to isolate active non-toxic antimalarial principles from these plants...
  87. ncbi The cytotoxic effects of a traditional Zulu remedy, impila (Callilepis laureola)
    M J Stewart
    Indigenous Toxicology Unit, Department of Chemical Pathology, University of the Witwatersrand, Gauteng, South Africa
    Hum Exp Toxicol 21:643-7. 2002
    ..In addition, we observed destruction of cytoplasmic tubulin. These findings give further insight into the mechanism of toxicity of herbal remedies containing atractyloside...
  88. ncbi Evaluation of the anti-asthmatic property of Asystasia gangetica leaf extracts
    P A Akah
    Department of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, University of Nigeria, Enugu State, Nsukka, Nigeria
    J Ethnopharmacol 89:25-36. 2003
    ..The study justified the use of the leaf of Asystasia gangetica in the management of asthma in Nigerian folk medicine...
  89. ncbi Indigenous knowledge system for treatment of trypanosomiasis in Kaduna state of Nigeria
    S E Atawodi
    Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria
    J Ethnopharmacol 79:279-82. 2002
    ..The method of preparation and mode of administration of some of these plants in the treatment of trypanosomiasis are reviewed and discussed...
  90. ncbi Analgesic properties of some ethiopian medicinal plants in different models of nociception in mice
    Eyasu Makonnen
    Department of Pharmacology, Faculty of Medicine, Addis Ababa University, Addis Ababa, Ethiopia
    Phytother Res 17:1108-12. 2003
    ..From the present findings, it can be concluded that the extracts of all the plant materials have got analgesic properties with fast onset of action whose mechanisms need to be investigated further...
  91. ncbi Investigation of the antimutagenic effects of selected South African medicinal plant extracts
    L Verschaeve
    Flemish Institute of Technological Research VITO, Expertise Centre of Environmental Toxicology, Boeretang 200, B 2400 Mol, Belgium
    Toxicol In Vitro 18:29-35. 2004
    ....
  92. ncbi Hypoglycemic effect of Hypoxis hemerocallidea corm (African potato) aqueous extract in rats
    I M Mahomed
    Department of Pharmacology, Faculty of Health Sciences, University of Durban Westville, Durban 4000, South Africa
    Methods Find Exp Clin Pharmacol 25:617-23. 2003
    ....
  93. ncbi Hepatoprotective activity of Trichilia roka on carbon tetrachloride-induced liver damage in rats
    M P Germano
    Pharmaco Biological Department, School of Pharmacy, Messina, Italy
    J Pharm Pharmacol 53:1569-74. 2001
    ..The hepatoprotective properties of Trichilia roka may be correlated to polyphenol content of the decoction and its diethyl ether-soluble fraction...
  94. ncbi Antimicrobial activity of some medicinal plants from Ghana
    G H Konning
    Department of Pharmaceutics, Faculty of Pharmacy, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana
    Fitoterapia 75:65-7. 2004
    ..The results of a preliminary antimicrobial screening of the methanol extracts of Aframomum melegueta, Piper guineense, Xylopia aethiopica, Zingiber officinale, medicinal plants of Ghana, are reported...
  95. ncbi Effects of the aqueous and methylene chloride extracts of Bidens pilosa leaf on fructose-hypertensive rats
    T Dimo
    Department of Animal Biology and Physiology, Faculty of Sciences, University of Yaounde I, PO Box 812, Yaounde, Cameroon
    J Ethnopharmacol 76:215-21. 2001
    ..These results suggest that the extracts of B. pilosa possess hypotensive effects whose mechanism of action is not related to insulin sensitivity...
  96. ncbi Interaction of some traditional plant extracts with uterine oestrogen or progestin receptors
    T Benie
    Laboratoire d Endocrinologie et de Biologie de la Reproduction, UFR Biosciences, BP 582 Abidjan 22, Cote d Ivoire
    Phytother Res 17:756-60. 2003
    ..These results suggest also that crude plant extracts may interfere with natural oestrogen and/or progestagen in vivo by binding to steroid receptors...
  97. ncbi Effects of some traditional plant extracts on rat oestrous cycle compared with Clomid
    T Benie
    Laboratoire Endocrinologie et de Biologie de la Reproduction, UFR Biosciences, Universite de Cocody, 22 BP 582 Abidjan, Cote d Ivoire
    Phytother Res 17:748-55. 2003
    ..In fact, A. laxiflora, P. erinaceus and C. nitida extracts inhibited gonadotropin release as an antiestrogen-like substance...
  98. ncbi In vitro antiplasmodial evaluation of medicinal plants from Zimbabwe
    Carola Kraft
    Institut für Pharmazie Pharmazeutische Biologie, Freie Universitat Berlin, Berlin, Germany
    Phytother Res 17:123-8. 2003
    ..1-4.8 microgram/mL)...
  99. ncbi Prophylactic effect of multi-herbal extract 'Agbo-Iba' on malaria induced in mice
    C Nwabuisi
    Department of Medical Microbiology and Parasitology, Faculty of Health Sciences, University of Ilorin, P M B 1515, Ilorin, Nigeria
    East Afr Med J 79:343-6. 2002
    ..To determine the efficacy of a multi-herbal preparation extract of 'Agbo-Iba' on rodent malaria induced in mice...
  100. ncbi Seasonal accumulation of anthraquinones in leaves of cultivated Cassia podocarpa Guill et Perr
    K A Abo
    Department of Pharmacognosy, Faculty of Pharmacy, College of Medicine, University of Ibadan, Ibadan, Nigeria
    Afr J Med Med Sci 31:171-3. 2002
    ..podocarpa for drug development. The inclusion of C. podocarpa in the African Pharmacopoeia will, no doubt, enhance its commercialization as laxative and for its antimicrobial effect...
  101. ncbi Antioxidant effects of Gongronema latifolium in hepatocytes of rat models of non-insulin dependent diabetes mellitus
    N H Ugochukwu
    Department of Chemistry, Florida Agricultural and Mechanical University, Florida, Tallahassee 32307, USA
    Fitoterapia 73:612-8. 2002
    ..These results suggest that the extracts from G. latifolium leaves could exert their antidiabetic activities through their antioxidant properties...

Research Grants4

  1. African Herbal Medicines: Infectious & Chronic Diseases
    Maurice Iwu; Fiscal Year: 2005
    ..target scientist, clinical researchers, industry and academia for a scientific discussion on African traditional medicine in the context of the treatment of modern disease...
  2. Dietary prevention of prostate cancer
    CHENDIL DAMODARAN; Fiscal Year: 2013
    ..Withaferin-A (WA), a bioactive compound of Withania somnifera, which is extensively used in Asian and African traditional medicine. WA displays impressive and selective activity against androgen- dependent and androgen-independent ..
  3. TICIPS: HIV/AIDS, Secondary Infections and Immune Modul*
    WILLIAM ROBERT FOLK; Fiscal Year: 2010
    ..L frutescens is thought to be among the most efficacious plants used in southern African traditional medicine. The plant has been used in indigenous settings to treat serious microbial infections, especially HIV ..
  4. Synthesis of Macrolides, Steroids, Cyclopentanoids, etc.
    BARRY TROST; Fiscal Year: 2009
    ..These new synthetic methods apply to many structural types beyond those illustrated and constitutes a significant to gain access to complex molecular targets more easily. ..