transverse myelitis

Summary

Summary: Inflammation of a transverse portion of the spinal cord characterized by acute or subacute segmental demyelination or necrosis. The condition may occur sporadically, follow an infection or vaccination, or present as a paraneoplastic syndrome (see also ENCEPHALOMYELITIS, ACUTE DISSEMINATED). Clinical manifestations include motor weakness, sensory loss, and incontinence. (Adams et al., Principles of Neurology, 6th ed, pp1242-6)

Top Publications

  1. ncbi Idiopathic recurrent transverse myelitis
    Kwang Kuk Kim
    Department of Neurology, University of Ulsan College of Medicine, Asan Medical Center, Songpa Gu, Seoul, South Korea
    Arch Neurol 60:1290-4. 2003
  2. ncbi Emergency department presentations of transverse myelitis: two case reports
    Heather S Hammerstedt
    Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Ann Emerg Med 46:256-9. 2005
  3. ncbi Neuromyelitis optica IgG predicts relapse after longitudinally extensive transverse myelitis
    Brian G Weinshenker
    Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Ann Neurol 59:566-9. 2006
  4. ncbi Idiopathic acute transverse myelitis: application of the recent diagnostic criteria
    J de Seze
    Department of Neurology, University of Lille, France
    Neurology 65:1950-3. 2005
  5. ncbi Lyme disease presenting as subacute transverse myelitis
    Filiz Koc
    Department of Neurology, Cukurova University School of Medicine, Adana, Turkey
    Acta Neurol Belg 109:326-9. 2009
  6. ncbi Clinical study of childhood acute disseminated encephalomyelitis, multiple sclerosis, and acute transverse myelitis in Fukuoka Prefecture, Japan
    Hiroyuki Torisu
    Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Brain Dev 32:454-62. 2010
  7. ncbi Acute transverse myelitis as a main manifestation of early stage II neuroborreliosis in two patients
    Liesbeth Meurs
    Department of Neurology, Clinique Sainte Elisabeth, Brussels, Belgium
    Eur Neurol 52:186-8. 2004
  8. ncbi Aquaporin-4 antibodies in neuromyelitis optica and longitudinally extensive transverse myelitis
    Patrick Waters
    Neurosciences Group, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford OX3 9DS, England
    Arch Neurol 65:913-9. 2008
  9. ncbi Acute partial transverse myelitis: risk factors for conversion to multiple sclerosis
    J Sellner
    Department of Neurology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland corrected
    Eur J Neurol 15:398-405. 2008
  10. ncbi Transverse myelitis secondary to coexistent Lyme disease and babesiosis
    Christina V Oleson
    Department of Rehabilitation Medicine, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA
    J Spinal Cord Med 26:168-71. 2003

Detail Information

Publications226 found, 100 shown here

  1. ncbi Idiopathic recurrent transverse myelitis
    Kwang Kuk Kim
    Department of Neurology, University of Ulsan College of Medicine, Asan Medical Center, Songpa Gu, Seoul, South Korea
    Arch Neurol 60:1290-4. 2003
    To determine whether idiopathic recurrent transverse myelitis (RTM) can be distinguished from multiple sclerosis-associated RTM (MSRTM) on the basis of clinical manifestations of myelopathy, or findings from magentic resonance imaging or ..
  2. ncbi Emergency department presentations of transverse myelitis: two case reports
    Heather S Hammerstedt
    Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Ann Emerg Med 46:256-9. 2005
    b>Transverse myelitis, a diagnosis that may be made in the emergency department (ED) by emergency physicians, can be difficult to diagnose because of its variable signs and symptoms and its poorly understood pathogenesis...
  3. ncbi Neuromyelitis optica IgG predicts relapse after longitudinally extensive transverse myelitis
    Brian G Weinshenker
    Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Ann Neurol 59:566-9. 2006
    We investigated whether neuromyelitis optica (NMO) IgG seropositivity at the initial presentation of longitudinally extensive transverse myelitis (LETM) predicts relapse of myelitis or development of optic neuritis.
  4. ncbi Idiopathic acute transverse myelitis: application of the recent diagnostic criteria
    J de Seze
    Department of Neurology, University of Lille, France
    Neurology 65:1950-3. 2005
    Despite an extensive diagnostic workup, some cases of acute transverse myelitis (ATM) remain of unknown etiology and have been referred to as "idiopathic" by the Transverse Myelitis Consortium group...
  5. ncbi Lyme disease presenting as subacute transverse myelitis
    Filiz Koc
    Department of Neurology, Cukurova University School of Medicine, Adana, Turkey
    Acta Neurol Belg 109:326-9. 2009
    ..Immunoglobulin M antibody to B. burgdorferi was positive on Western blotting in both serum and cerebrospinal fluid. The patient was diagnosed with subacute neuroborreliosis and treated...
  6. ncbi Clinical study of childhood acute disseminated encephalomyelitis, multiple sclerosis, and acute transverse myelitis in Fukuoka Prefecture, Japan
    Hiroyuki Torisu
    Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Brain Dev 32:454-62. 2010
    ..conducted a multicenter, population-based study on childhood ADEM, multiple sclerosis, and acute isolated transverse myelitis in Fukuoka Prefecture, Japan...
  7. ncbi Acute transverse myelitis as a main manifestation of early stage II neuroborreliosis in two patients
    Liesbeth Meurs
    Department of Neurology, Clinique Sainte Elisabeth, Brussels, Belgium
    Eur Neurol 52:186-8. 2004
  8. ncbi Aquaporin-4 antibodies in neuromyelitis optica and longitudinally extensive transverse myelitis
    Patrick Waters
    Neurosciences Group, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford OX3 9DS, England
    Arch Neurol 65:913-9. 2008
    ..There is increasing recognition of antibody-mediated immunotherapy-responsive neurologic diseases and a need for appropriate immunoassays...
  9. ncbi Acute partial transverse myelitis: risk factors for conversion to multiple sclerosis
    J Sellner
    Department of Neurology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland corrected
    Eur J Neurol 15:398-405. 2008
    Acute partial transverse myelitis (APTM) may be the first clinical manifestation of multiple sclerosis (MS), of relapsing myelitis, or remain a monophasic event...
  10. ncbi Transverse myelitis secondary to coexistent Lyme disease and babesiosis
    Christina V Oleson
    Department of Rehabilitation Medicine, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA
    J Spinal Cord Med 26:168-71. 2003
    To describe transverse myelitis secondary to coexistent Lyme disease and babesiosis.
  11. ncbi Recurrent transverse myelitis associates with anti-Ro (SSA) autoantibodies
    L K Hummers
    Department of Medicine, Johns Hopkins University, Baltimore, MD 21224, USA
    Neurology 62:147-9. 2004
    b>Transverse myelitis (TM) is an idiopathic inflammatory disorder of the spinal cord...
  12. ncbi Acute transverse myelitis following dengue virus infection
    Raymond C S Seet
    Division of Neurology, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074, Singapore
    J Clin Virol 35:310-2. 2006
    The spinal cord is infrequently affected following dengue virus infection. We report a case of transverse myelitis that developed 2 weeks after acute dengue infection and review the literature to elucidate the pathogenesis of spinal cord ..
  13. ncbi Neuromyelitis optica IgG status in acute partial transverse myelitis
    Thomas F Scott
    Department of Neurology, Drexel University College of Medicine and Allegheny General Hospital, Pittsburgh, PA, USA
    Arch Neurol 63:1398-400. 2006
    ..Furthermore, a high proportion of patients with longitudinally extensive transverse myelitis (characterized by spinal cord lesions extending 3 vertebral segments or more on magnetic resonance imaging) ..
  14. ncbi Neuromyelitis optica (NMO) antibody positivity in patients with transverse myelitis and no visual manifestations
    Sheri E Hamnik
    Loyola University Medical Center, Maywood, IL 60153, USA
    Semin Ophthalmol 23:191-200. 2008
    ..To describe a subgroup of patients with IgG antibody to Aquaporin 4 Protein (AQP4) specific to neuromyelitis optica (NMO), who did not have clinical manifestations of optic nerve involvement at the time of diagnosis...
  15. ncbi Acute transverse myelitis with normal brain MRI : long-term risk of MS
    Jui Perumal
    Multiple Sclerosis Center, Dept of Neurology, Wayne State University School of Medicine, Detroit, MI, USA
    J Neurol 255:89-93. 2008
    To investigate the long-term risk of developing MS in patients presenting with acute transverse myelitis (ATM) and normal brain MRI scans at onset.
  16. ncbi Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis)
    Raimundo N Q Leão
    Departamento de Saude Comunitaria, Universidade do Estado do Pará, Belem, PA, Brazil
    Rev Soc Bras Med Trop 35:401-4. 2002
    ..patient with febrile illness and thrombocytopenia complicated by neurological involvement characterized by transverse myelitis followed by weakness of both legs and flaccid paralysis...
  17. ncbi Proposed diagnostic criteria and nosology of acute transverse myelitis
    Gustavo C Roman
    Neurology 60:730-1; author reply 730-1. 2003
  18. ncbi The clinical course of idiopathic acute transverse myelitis in patients from Rio de Janeiro
    Marina Papais Alvarenga
    Departamento de Neurologia, Universidade Federal do Estado do Rio de Janeiro, Rua Mariz e Barros 775, Tijuca, Rio de Janeiro 20270 004, Brazil
    J Neurol 257:992-8. 2010
    The aim of this study was to describe the demographic, clinical and laboratory features of idiopathic acute transverse myelitis (IATM)...
  19. ncbi Protein culprit found for transverse myelitis?
    Helen Pilcher
    Lancet Neurol 4:702. 2005
  20. ncbi Acute transverse myelitis in children: clinical course and prognostic factors
    Pierre Defresne
    Service de Neurologie, Departement de Pediatrie, Cliniques Universitaires Saint Luc, Universite Catholique de Louvain, Bruxelles, Belgium
    J Child Neurol 18:401-6. 2003
    The objective of this study was to describe the clinical course of acute transverse myelitis in children, to identify prognostic factors, and to compare our findings with published data Twenty-four children, aged 2 to 14 years and ..
  21. ncbi Transverse myelitis following general and epidural anaesthesia in a paediatric patient
    E Martinez-Garcia
    Department of Anaesthesia, Children University Hospital, Nino Jesus, Madrid, Spain
    Anaesthesia 60:921-3. 2005
    A 13-year-old girl developed transverse myelitis 2 weeks after an uncomplicated, combined general and epidural anaesthetic for orthopaedic surgery. Since epidural anaesthesia had been used, a causal relationship might have been assumed...
  22. ncbi Acute partial transverse myelitis with normal cerebral magnetic resonance imaging: transition rate to clinically definite multiple sclerosis
    Thomas F Scott
    Drexel University College of Medicine, Allegheny General Hospital, Pittsburgh, PA 15212, USA
    Mult Scler 11:373-7. 2005
    To determine the long-term risk of developing clinically definite multiple sclerosis (CDMS) in patients with acute partial transverse myelitis (APTM) and normal cerebral magnetic resonance imaging (MRI) scans.
  23. ncbi Recurrent transverse myelitis following neurobrucellosis: immunologic features and beneficial response to immunosuppression
    Chitra Krishnan
    Department of Neurology, Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    J Neurovirol 11:225-31. 2005
    ..report the clinical course and immune system response of a patient with disease-associated recurrent transverse myelitis (TM) following cerebral infection with Brucellosis melitensis...
  24. ncbi Acute transverse myelitis after Japanese B encephalitis vaccination in a 4-year-old girl
    Mika Matsui
    Department of Child Development, Kumamoto University School of Medicine, 1 1 1 Honjo, Kumamoto 860 0811, Japan
    Brain Dev 24:187-9. 2002
    ..Although the pathological process remains unknown, cellular autoimmune mechanism against the JBE vaccination is suspected...
  25. ncbi Transverse myelitis in a patient with primary antiphospholipid syndrome
    Dong Min Lee
    Division of Rheumatology, Department of Internal Medicine, Chonbuk National University Medical School, and Research Institute of Clinical Medicine, 634 18 Keumam dong, Duckjin Gu, Chonju, Chonbuk 561 712, Korea
    Yonsei Med J 44:323-7. 2003
    The neurological manifestations of antiphospholipid syndrome (APS) are diverse. Transverse myelitis (TM) is an uncommon, but well-known neurological complication of systemic lupus erythematosus (SLE)...
  26. ncbi Compartmentalization of the immune response in varicella zoster virus immune restoration disease causing transverse myelitis
    Benjamin M Clark
    AIDS 18:1218-21. 2004
  27. pmc Bladder dysfunction in acute transverse myelitis: magnetic resonance imaging and neurophysiological and urodynamic correlations
    J Kalita
    Department of Neurology, Sanjay Gandhi PGIMS, Lucknow, India
    J Neurol Neurosurg Psychiatry 73:154-9. 2002
    To evaluate micturition abnormalities in acute transverse myelitis and correlate these with evoked potentials, magnetic resonance imaging (MRI), and urodynamic findings.
  28. ncbi Acute transverse myelitis: a practical reappraisal
    Maria José Sá
    Department of Neurology, Hospital S Joao, Alameda Professor Hernani Monteiro, Porto, Portugal
    Autoimmun Rev 9:128-31. 2009
    Acute transverse myelitis (ATM), a subgroup of various conditions that cause transverse spinal cord syndromes, is an inflammatory and usually idiopathic spinal cord disease...
  29. ncbi Unusual complications of heroin abuse: transverse myelitis, rhabdomyolysis, compartment syndrome, and ARF
    Vaibhav Sahni
    Department of Internal Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA
    Clin Toxicol (Phila) 46:153-5. 2008
    ..We report here the simultaneous presentation of multiple complications of heroin toxicity...
  30. pmc Acute transverse myelitis associated with dengue viral infection
    Nouansompheng Chanthamat
    Department of Internal Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand
    J Spinal Cord Med 33:425-7. 2010
    Acute transverse myelitis is a rare manifestation of dengue viral infection. Four cases have been previously reported in the literature.
  31. ncbi Transverse myelitis in a patient with long-standing ankylosing spondylitis
    D H Oh
    Hospital for Rheumatic Diseases, Hanyang University, Seoul, Korea
    Clin Exp Rheumatol 19:195-6. 2001
    ..of a spastic paraparesis failed and therefore led to the conclusion that this patient was suffering from transverse myelitis. Similar reports in the past have been attributed to an association with multiple sclerosis; however, we ..
  32. ncbi Cytomegalovirus-associated acute transverse myelitis in immunocompetent adults
    C A Fux
    Institute for Infectious Diseases, University of Bern, Switzerland
    Clin Microbiol Infect 9:1187-90. 2003
    We report a case of transverse myelitis as a complication of acute cytomegalovirus (CMV) infection in immunocompetent patients; and review the literature on the entity...
  33. ncbi Concomitant transverse myelitis and acute motor axonal neuropathy in an adolescent
    Katherine B Howell
    Children s Neurosciences Centre, Royal Children s Hospital, Melbourne, Victoria, Australia
    Pediatr Neurol 37:378-81. 2007
    ..Imaging and neurophysiologic studies were diagnostic for transverse myelitis with acute motor axonal neuropathy...
  34. ncbi Venous hypertensive myelopathy as a potential mimic of transverse myelitis
    C Krishnan
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Spinal Cord 42:261-4. 2004
    ..Case report...
  35. ncbi Acute transverse myelitis and hepatitis C virus
    Pasquale Annunziata
    Department of Neurological Sciences and Behaviour, Centre for Research on Multiple Sclerosis and Neuroimmunological Diseases, University of Siena, Siena, Italy
    Infez Med 13:45-7. 2005
    ..Here, we report a case of acute transverse myelitis in a woman developing 4 years after documented HCV seropositivity, associated with intrathecal anti-HCV ..
  36. ncbi Acupuncture for back pain, knee pain and insomnia in transverse myelitis - a case report
    Sonia A Vaghela
    Senior Physiotherapist, Linden lodge Neuro Rehabilitation Unit, Nottingham University Hospitals, NHS Trust, UK
    Acupunct Med 26:188-92. 2008
    ..use of acupuncture for back pain, knee pain and insomnia in a 49 year old woman with a recent diagnosis of transverse myelitis with paraplegia, sensory disturbance, and bladder and bowel dysfunction...
  37. ncbi Transverse myelitis in systemic sclerosis
    Amir M Torabi
    Department of Neurology, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390 8897, USA
    Arch Neurol 61:126-8. 2004
    ..Neurological involvement occurs rarely with systemic sclerosis (SSc). Only a few cases of transverse myelopathy have been reported in the setting of SSc...
  38. ncbi Transverse myelitis as a rare, serious complication of Mycoplasma pneumoniae infection
    Györgyi Csábi
    Department of Pediatrics, University of Pecs, 7623 Pecs, Hungary
    Pediatr Neurol 41:312-3. 2009
    We report on the first published case of a Mycoplasma pneumoniae-associated transverse myelitis appearing in childhood and leading to persistent paraplegia and bowel and bladder dysfunctions...
  39. ncbi Idiopathic acute transverse myelitis: a clinical study and prognostic markers in 45 cases
    J Bruna
    Department of Neurology, Hospital Universitari de Bellvitge, Institut d Investigacio Biomedica de Bellvitge, Universitat de Barcelona, Spain
    Mult Scler 12:169-73. 2006
    The Transverse Myelitis Consortium Working Group has proposed new diagnostic criteria for idiopathic acute transverse myelitis (ATM)...
  40. ncbi Clinical characteristics, prognosis, and seropositivity to the anti-aquaporin-4 antibody in Korean patients with longitudinally extensive transverse myelitis
    Su Hyun Kim
    Department of Neurology, Seoul National University College of Medicine, 28 Yon Gun Dong, Chong Ro, Seoul, Korea
    J Neurol 257:920-5. 2010
    Longitudinally extensive transverse myelitis (LETM) is a syndrome with extensive spinal cord lesions spanning three or more vertebral segments on spinal cord MRI...
  41. ncbi Aquaporin-4 antibody positive longitudinally extensive transverse myelitis following varicella zoster infection
    Kristin Heerlein
    Division of Molecular Neuroimmunology, Department of Neurology, University of Heidelberg, Germany
    J Neurol Sci 276:184-6. 2009
    Longitudinally extensive transverse myelitis (LETM) is a condition shown to confer high risk of conversion into neuromyelitis optica (NMO)...
  42. ncbi Acute transverse myelitis associated with scrub typhus: case report and a review of literatures
    Kwang Lae Lee
    Department of Rehabilitation Medicine, Gachon University of Medicine and Science, Incheon 405 760, Korea
    Diagn Microbiol Infect Dis 60:237-9. 2008
    We describe a rare case of acute transverse myelitis associated with scrub typhus...
  43. ncbi Transverse myelitis and vaccines: a multi-analysis
    N Agmon-Levin
    Center for Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Israel
    Lupus 18:1198-204. 2009
    b>Transverse myelitis is a rare clinical syndrome in which an immune-mediated process causes neural injury to the spinal cord...
  44. ncbi Transverse myelitis associated to HCV infection
    Diego Michelon de Carli
    Clinica Medica, Hospital Universitario de Santa Maria, Rua dos Andradas no 1125 301, Santa Maria, RS, Brazil
    Braz J Infect Dis 13:147-52. 2009
    ..Among them, it appears the transverse myelitis, which has already been reported in likely association with HCV...
  45. ncbi Transverse myelitis as the first manifestation of systemic lupus erythematosus or lupus-like disease: good functional outcome and relevance of antiphospholipid antibodies
    David P D'Cruz
    Louise Coote Lupus Unit, St Thomas Hospital, London Rivermead Rehabilitation Centre, Oxford, United Kingdom
    J Rheumatol 31:280-5. 2004
    b>Transverse myelitis (TM) is a rare complication of systemic lupus erythematosus (SLE). Although usually a late manifestation of SLE, it can occur at presentation...
  46. ncbi [Case of recurrent transverse myelitis and diplopia after meningomyeloradiculitis caused by Epstein-Barr virus]
    Masayuki Ochi
    Department of Geriatric Medicine, Medicine and Bioscience, Graduate School of Medicine, Ehime University
    Rinsho Shinkeigaku 47:348-52. 2007
    ..The symptoms improved after steroid pulse therapy, but relapses of transverse myelitis and diplopia due to disturbance of the bilateral abducent nerves and left trochlear nerve occurred 7, 12, ..
  47. doi Severe hypertension and bradycardia after dexmedetomidine for radiology sedation in a patient with acute transverse myelitis
    Shailesh Shah
    Paediatr Anaesth 18:681-2. 2008
  48. ncbi Leptospirosis with transverse myelitis
    S Kavitha
    J Assoc Physicians India 53:159-60. 2005
  49. ncbi Acute transverse myelitis following hepatitis E virus infection
    Kausik Mandal
    Indian Pediatr 43:365-6. 2006
  50. ncbi Nosology of idiopathic transverse myelitis syndromes
    Thomas F Scott
    Department of Neurology, Drexel University College of Medicine, Allegheny General Hospital, Pittsburgh, PA 15212, USA
    Acta Neurol Scand 115:371-6. 2007
    ..Several terms are now commonly used to describe various presentations of idiopathic myelitis, including acute transverse myelitis, acute partial transverse myelitis, and secondary myelitis...
  51. ncbi Discriminatory features of acute transverse myelitis: a retrospective analysis of 45 patients
    Michael Harzheim
    Department of Neurology, University of Bonn, Sigmund Freud Str 25, D 53105, Bonn, Germany
    J Neurol Sci 217:217-23. 2004
    Acute transverse myelitis (ATM) is a pathogenetically heterogeneous inflammatory disorder of the spinal cord. Therefore, the identification of clinical and paraclinical features providing clues of the underlying etiologies is needed...
  52. ncbi Inflammatory transverse myelitis: evolving concepts
    Sean J Pittock
    Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Curr Opin Neurol 19:362-8. 2006
    Acute transverse myelitis is a pathogenetically heterogeneous inflammatory disorder of the spinal cord. Here we describe recent advances in inflammatory non-infectious transverse myelitis...
  53. ncbi Determinants of prognosis of acute transverse myelitis in children
    Reiko Miyazawa
    Department of Pediatrics, Tone Central Hospital, Numata, Gunma University School of Medicine, Maebashi and Saku Central Hospital, Minamisaku, Nagano, Japan
    Pediatr Int 45:512-6. 2003
    Acute transverse myelitis (ATM) is a severe disorder; recovery requires several months and often leaves neurologic residua...
  54. ncbi Is methyl prednisolone useful in acute transverse myelitis?
    J Kalita
    Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareli Road, Lucknow 226 014, India
    Spinal Cord 39:471-6. 2001
    ..Hospital based observational study...
  55. ncbi Acute transverse myelitis in childhood: center-based analysis of 47 cases
    F S Pidcock
    Department of Physical Medicine and Rehabilitation, Kennedy Krieger Institute, Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA
    Neurology 68:1474-80. 2007
    To relate clinical characteristics associated with acute transverse myelitis (ATM) in children with functional outcomes at follow-up.
  56. ncbi Can electromyography predict the prognosis of transverse myelitis?
    U K Misra
    Department of Neurology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Neurol 245:741-4. 1998
    The role of clinical and magnetic resonance imaging (MRI) features on the prognosis of acute transverse myelitis has been studied, but the role of electromyography (EMG) changes, although reported, has not been investigated...
  57. ncbi Idiopathic severe recurrent transverse myelitis: a restricted variant of neuromyelitis optica
    Koon Ho Chan
    Division of Neurology, University Department of Medicine, 4th Floor, Professorial Block, Pokfulam Road, Queen Mary Hospital, The University of Hong Kong, Hong Kong, SAR, China
    Clin Neurol Neurosurg 107:132-5. 2005
    Recurrent idiopathic transverse myelitis occur in multiple sclerosis (MS) and neuromyelitis optica (NMO)...
  58. ncbi Neurophysiological studies in acute transverse myelitis
    J Kalita
    Department of Neurology, Sanjay Gandhi PGIMS, Lucknow 226014, India
    J Neurol 247:943-8. 2000
    ..and somatosensory (SEPs) evoked potentials, respectively, which may provide valuable information on acute transverse myelitis (ATM)...
  59. pmc Efficacy of high dose steroid therapy in children with severe acute transverse myelitis
    P Defresne
    Service de Neurologie, Departement de Pediatrie, Cliniques Universitaires Saint Luc, Universite Catholique de Louvain, Avenue Hippocrate 10, 1200 Bruxelles, Belgium
    J Neurol Neurosurg Psychiatry 71:272-4. 2001
    ..The treatment had a significant effect on the proportion of patients walking independently at 1 month and on the proportion with full recovery at 1 year, with no differences in the frequency of complications between the two groups...
  60. ncbi Transverse myelitis spectrum disorders
    Lekha Pandit
    Department of Neurology, KS Hegde Medical Academy, Mangalore, India
    Neurol India 57:126-33. 2009
    Acute transverse myelitis (ATM) is an inflammatory demyelinating disorder that affects the spinal cord focally resulting in motor sensory and autonomic dysfunction...
  61. ncbi Interleukin-17 in transverse myelitis and multiple sclerosis
    Jerome J Graber
    The Johns Hopkins University School of Medicine, Department of Neurology, Baltimore, MD 21287 6965, United States
    J Neuroimmunol 196:124-32. 2008
    CSF IL-6 is elevated in transverse myelitis (TM) and predicts disability...
  62. ncbi Re: transverse myelitis after measles and rubella vaccination
    Milan Cizman
    J Paediatr Child Health 41:460. 2005
  63. pmc IL-6 induces regionally selective spinal cord injury in patients with the neuroinflammatory disorder transverse myelitis
    Adam I Kaplin
    Department of Psychiatry and Behavioral Sciences, Bloomberg School of Public Health, Baltimore, Maryland, USA
    J Clin Invest 115:2731-41. 2005
    b>Transverse myelitis (TM) is an immune-mediated spinal cord disorder associated with inflammation, demyelination, and axonal damage...
  64. ncbi Transverse myelitis in 2 patients with Bartonella henselae infection (cat scratch disease)
    Peter Baylor
    Department of Medicine, Veteran s Affairs Medical Center, Fresno, CA 93703, USA
    Clin Infect Dis 45:e42-5. 2007
    ..This report describes 2 cases of transverse myelitis: 1 case in a 46-year-old man who had lymph node biopsy and serological testing results that were positive ..
  65. ncbi Acute transverse myelitis in a 7-month-old boy after diphtheria-tetanus-pertussis immunization
    R M S Riel-Romero
    Department of Neurology, University of Kentucky, Kentucky, USA
    Spinal Cord 44:688-91. 2006
    Case report of a 7-month-old boy, who developed acute transverse myelitis after diphtheria-tetanus-pertussis immunization.
  66. ncbi Mycoplasma pneumoniae--associated transverse myelitis and rhabdomyolysis
    Wen Chin Weng
    Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan
    Pediatr Neurol 40:128-30. 2009
    ..previously healthy 4-year-old boy who displayed a novel simultaneous onset of both acute rhabdomyolysis and transverse myelitis associated with an infection of M. pneumoniae...
  67. ncbi An approach to the diagnosis of acute transverse myelitis
    Anu Jacob
    Division of Neurology, Walton Centre for Neurology and Neurosurgery, Liverpool, United Kingdom
    Semin Neurol 28:105-20. 2008
    The differential diagnosis of acute inflammatory transverse myelitis (ATM) is broad...
  68. ncbi [Myelopathy due to vitamin B12 deficiency presenting as transverse myelitis]
    Luiz Felipe Rocha Vasconcellos
    Instituto de Neurologia Deolindo Couto, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil
    Arq Neuropsiquiatr 60:150-4. 2002
    ..We report a case with transverse myelitis due to vitamin B12 deficiency...
  69. ncbi Combination of transverse myelitis and arachnoiditis in cauda equina syndrome of long-standing ankylosing spondylitis: MRI features and its role in clinical management
    Howard Haw Chang Lan
    Department of Radiology, Taichung Veterans General Hospital, Taichung, Taiwan, Republic of China
    Clin Rheumatol 26:1963-7. 2007
    ..We report a patient of CES-AS in whom MRI disclosed acute transverse myelitis and arachnoiditis along the lower spinal cord, and discuss the pathogenesis of CES-AS and the role of MRI ..
  70. ncbi Immunopathogenesis of acute transverse myelitis
    Douglas A Kerr
    Department of Neurology, School of Medicine, Johns Hopkins University, Pathology 627 C, 6000 N Wolfe Street, Baltimore, MD 21287 6965, USA
    Curr Opin Neurol 15:339-47. 2002
    Acute transverse myelitis is a group of disorders characterized by focal inflammation of the spinal cord and resultant neural injury...
  71. ncbi Acute transverse myelitis and Guillain-Barré overlap syndrome with serological evidence for mumps viraemia
    N P Bajaj
    Department of Neurology, Hurstwood Park Neurology Centre, Hurstwood Lane, West Sussex, United Kingdom
    Acta Neurol Scand 104:239-42. 2001
    Both acute transverse myelitis (ATM) and Guillain-Barré syndrome (GBS) occur as rare associations with mumps viraemia but to our knowledge, concurrent ATM and GBS related to mumps has only been reported once previously...
  72. ncbi Transverse myelitis after vaccination
    G Zanoni
    Eur J Neurol 9:696-7. 2002
  73. ncbi Idiopathic transverse myelitis: corticosteroids, plasma exchange, or cyclophosphamide
    B M Greenberg
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287 5371, USA
    Neurology 68:1614-7. 2007
    b>Transverse myelitis is a focal disorder of the spinal cord in which an immune-mediated process results in neural injury...
  74. ncbi Transverse Myelitis: pathogenesis, diagnosis and treatment
    Chitra Krishnan
    Department of Neurology, Johns Hopkins Transverse Myelitis Center, 600 N Wolfe Street Pathology 627C, Baltimore MD 21287 6965, USA
    Front Biosci 9:1483-99. 2004
    b>Transverse Myelitis (TM) is a clinical syndrome in which an immune-mediated process causes neural injury to the spinal cord, resulting in varying degrees of weakness, sensory alterations and autonomic dysfunction...
  75. ncbi A case of Sjögren's syndrome with acute transverse myelitis and polyneuropathy in a patient free of sicca symptoms
    Antonio G Tristano
    Clin Rheumatol 25:113-4. 2006
    Acute transverse myelitis (ATM) is an inflammatory process involving a restricted area of the spinal cord...
  76. ncbi Atypical transverse myelitis due to cytomegalovirus in an immunocompetent patient
    A Rigamonti
    National Neurological Institute C Besta, Via Celoria 11, I 20133 Milan, Italy
    Neurol Sci 26:351-4. 2005
    Cytomegalovirus (CMV)-associated transverse myelitis is rare in immunocompetent patients. We report a 73-year-old man with no evidence of immune compromise, who developed acute transverse myelitis...
  77. ncbi 14-3-3 Protein in the cerebrospinal fluid of patients with acute transverse myelitis and multiple sclerosis
    Jerome De Seze
    J Neurol 249:626-7. 2002
  78. ncbi Diffusion tensor imaging in idiopathic acute transverse myelitis
    Joon Woo Lee
    Department of Radiology, Seoul National University Bundang Hospital, Gyeonggi Do, Korea
    AJR Am J Roentgenol 191:W52-7. 2008
    Our study was based on our hypotheses that in idiopathic acute transverse myelitis (ATM), fractional anisotropy (FA) values would be abnormal not only in the T2-hyperintense lesion but also in the surrounding normal-appearing spinal cord ..
  79. ncbi Transverse myelitis associated with chronic hepatitis C
    G Zandman-Goddard
    Rheumatology Unit, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Israel
    Clin Exp Rheumatol 21:111-3. 2003
    ..An emergence of autoimmune phenomena associated with hepatitis C virus (HCV) infection has been reported. Transverse myelitis is an inflammatory disease of the spinal vasculature attributed to viral infections and to autoimmune ..
  80. ncbi Childhood acute transverse myelitis: clinical profile, outcome, and association with antiganglioside antibodies
    Veena Kalra
    Department of Pediatrics, All India Institute of Medical Sciences, New Delhi 110029, India
    J Child Neurol 24:466-71. 2009
    Prospectively, in 15 children the association of acute transverse myelitis with Campylobacter jejuni infection and antiganglioside antibodies was studied...
  81. ncbi Longitudinal myelitis associated with systemic lupus erythematosus: clinical features and magnetic resonance imaging of six cases
    J F Tellez-Zenteno
    Department of Neurology and Psychiatry, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico
    Lupus 10:851-6. 2001
    ..Acute transverse myelitis (ATM) is the most frequent form of SLE-related myelopathy...
  82. ncbi Transverse myelitis affecting more than 4 spinal segments associated with systemic lupus erythematosus: clinical, immunological, and radiological characteristics of 22 patients
    Gerard Espinosa
    Department of Autoimmune Diseases, Institut Clinic de Medicina i Dermatologia, Hospital Clinic, Barcelona, Catalonia, Spain
    Semin Arthritis Rheum 39:246-56. 2010
    To analyze the clinical and laboratory characteristics and outcomes of patients with transverse myelitis affecting more than 4 spinal segments secondary to systemic lupus erythematosus (SLE).
  83. ncbi Systemic lupus erythematosus related transverse myelitis presenting longitudinal involvement of the spinal cord
    Kato Yu ko Kimura
    First Department of Internal Medicine, Nippon Medical School, Tokyo
    Intern Med 41:156-60. 2002
    Lupus-related transverse myelitis is a rare but serious complication...
  84. ncbi Involvement of the entire spinal cord and medulla oblongata in acute catastrophic-onset transverse myelitis in SLE
    G Neumann-Andersen
    Department of Rheumatology, University Hospital of Umea, Sweden
    Clin Rheumatol 19:156-60. 2000
    A 30-year-old Caucasian male with systemic lupus erythematosus suffered acute catastrophic-onset transverse myelitis. Two years earlier aseptic meningitis, another rare CNS lupus manifestation, had been diagnosed...
  85. ncbi Idiopathic acute transverse myelitis: application of the recent diagnostic criteria
    Yasuo Iwasaki
    Neurology 67:728; author reply 728. 2006
  86. doi Simultaneous transverse myelitis and acute motor axonal neuropathy in an adult
    S Saidha
    J Neurol Neurosurg Psychiatry 79:1302-3. 2008
  87. ncbi Campylobacter jejuni-induced acute transverse myelitis
    I Baar
    Department of Neurology, University Hospital of Antwerp, Edegem, Belgium
    Spinal Cord 45:690-4. 2007
    ..Case report...
  88. ncbi CNS aquaporin-4 autoimmunity in children
    A McKeon
    Departments of Neurology and Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Neurology 71:93-100. 2008
    ..Here we describe the neurologic, serologic, and radiographic findings associated with CNS AQP4 autoimmunity in childhood...
  89. ncbi [A case of Sjögren's syndrome with subacute transverse myelitis as the initial manifestation]
    Chieko Arai
    Department of Internal Medicine, Kenwakai Hospital
    Rinsho Shinkeigaku 42:613-8. 2002
    We report a case of subacute transverse myelitis associated with Sjögren's syndrome free of xerosis...
  90. ncbi [Varicella zoster virus infection after bone marrow transplant. Unusual presentation and importance of prevention]
    M LaDriere
    Service de Maladies Infectieuses et Tropicales, Centre Hospitalier Universitaire de Nancy
    Presse Med 30:1151-4. 2001
    ..Although infrequent, visceral involvement can be fatal. We report two cases of patients presenting severe VZV infection after bone marrow transplantation...
  91. ncbi Occurrence of CNS demyelinating disease in patients with myasthenia gravis
    Ken Ikeda
    Neurology 68:1326; author reply 1327. 2007
  92. ncbi Idiopathic inflammatory-demyelinating diseases of the central nervous system
    A Rovira Cañellas
    Magnetic Resonance Unit I D I, Department of Radiology, Vall d Hebron University Hospital, Pg Vall d Hebron 119 129, Barcelona 08035, Spain
    Neuroradiology 49:393-409. 2007
    ..acute disseminated encephalomyelitis; (2) monosymptomatic IIDDs, such as those involving the spinal cord (transverse myelitis), optic nerve (optic neuritis) or brainstem and cerebellum; and (3) IIDDs with a restricted topographical ..
  93. ncbi Transverse myelopathy: an initial presentation of acute leukemia
    H Yavuz
    Department of Pediatrics, Faculty of Medicine, , 25/8 Konya, Turkey
    Pediatr Neurol 24:382-4. 2001
    ..Transverse myelopathy can be the initial presentation of acute lymphoblastic leukemia...
  94. ncbi Neuromyelitis optica-IgG in childhood inflammatory demyelinating CNS disorders
    B Banwell
    Division of Pediatric Neurology and the Research Institute, The Hospital for Sick Children, University of Toronto, Canada
    Neurology 70:344-52. 2008
    ..To determine seroprevalence of neuromyelitis optica (NMO)-IgG in childhood CNS inflammatory demyelinating disorders...
  95. ncbi [Acute myelitis and Lyme disease]
    F Blanc
    Departement de Neurologie, Hopitaux Universitaires de Strasbourg, Strasbourg
    Rev Neurol (Paris) 163:1039-47. 2007
    ..In the literature, simultaneous spinal MRI and cerebrospinal fluid (CSF) investigations are presented for only 8 cases. We describe here 3 cases of acute Lyme myelitis...
  96. ncbi Analysis of the full-length genome of hepatitis B virus in the serum and cerebrospinal fluid of a patient with acute hepatitis B and transverse myelitis
    Jun Inoue
    Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980 8574, Japan
    J Clin Virol 41:301-4. 2008
    ..We describe a 55-year-old man who contracted acute hepatitis B virus (HBV) infection and transverse myelitis. His neurological findings were gradually reduced along with the recovery from hepatitis...
  97. ncbi Idiopathic recurrent transverse myelitis with syringomyelia: a case report
    Olcay Eser
    Afyon Kocatepe University, Faculty of Medicine, Neurosurgery Department, Afyonkarahisar, Turkey
    Turk Neurosurg 17:228-31. 2007
    Idiopathic transverse myelitis is a monophasic demyelinating disease of the central nervous system (CNS) and its recurrence is a rare entity...
  98. ncbi Motor dominant neuropathy in Sjögren's syndrome: report of two cases
    Hitoshi Mochizuki
    Third Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama
    Intern Med 41:142-6. 2002
    ..These patients received i.v. immunoglobulin therapy. To our knowledge, this is the first report indicating that i.v. immunoglobulin has beneficial effects on motor dominant neuropathy in SS...
  99. ncbi The Case | Acute paraplegia with anuric ARF. Occlusive aortic thrombus with ischemia of spinal cord and kidneys
    K Sampathkumar
    Department of Nephrology, Meenakshi Mission Hospital and Research Centre, Madurai, Tamil Nadu 625107, India
    Kidney Int 72:657-9. 2007
  100. ncbi Transverse myelitis in systemic lupus erythematosus
    Yasuo Suzuki
    Intern Med 41:327-8. 2002
  101. ncbi Transient myelopathy of the cervical posterior columns in a young man with recently diagnosed diabetes mellitus
    J J Prick
    Department of Neurology, Medisch Spectrum Twente, loc. Oldenzaal, PO Box 50000, 7500 KA, Enschede, The Netherlands
    Clin Neurol Neurosurg 103:234-7. 2001
    ....

Research Grants14

  1. CNS Demyelinating Autoimmunity Targeting Water Channel Complexes
    SEAN JOSEPH PITTOCK; Fiscal Year: 2013
    ..It is characterized by recurrent episodes of optic neuritis and transverse myelitis, resulting in blindness and paraplegia in most patients, and it is frequently misdiagnosed as MS...
  2. Neuroimmune modulation across the BBB: Regulation of ILS trafficking by TNF
    Weihong Pan; Fiscal Year: 2012
    ..g., multiple sclerosis, transverse myelitis, acute disseminating encephalomyelopathy), tumor, a variety of neurodegenerative disorders (e.g...
  3. Advanced Quantitative MRI of the Cervical Spinal Cord in Demyelinating Disease
    John W Rose; Fiscal Year: 2013
    ..of the spinal cord for demyelinating diseases including multiple sclerosis (MS) and acute partial transverse myelitis (ATM) with DTI will result in better understanding of the disease pathology, prognosis and treatment ..
  4. Depression and Cognitive Impairment in Transverse Myelitis
    ADAM IAN KAPLIN; Fiscal Year: 2010
    ..depression and cognitive impairment will be investigated in patients with Multiple Sclerosis (MS) and Transverse Myelitis (TM)...
  5. Interferon Gamma Polymorphisms and Gender Bias in MS
    Brian Weinshenker; Fiscal Year: 2004
    ..If successful, this paradigm could be applied to a number of similar genetic association studies. ..
  6. Sjogren's model with anti-Ro/La and Salivary Pathology and Dysfunction
    R Hal Scofield; Fiscal Year: 2010
    ..Improved understanding of the disease at a fundamental level is possible through study of animal models. Such understanding may lead to improved recognition and treatment. ..
  7. Genetics of Severe Systemic Lupus Erythematosus (SLE) defined by thrombocytopenia
    R Scofield; Fiscal Year: 2007
    ..Finally, Specific Aim 4 will assemble a new cohort of families multiplex for SLE so that linkages and associations as well as particular polvmorphisms can be prospectively confirmed. ..
  8. The X chromosome in systemic lupus erythematosus
    R Hal Scofield; Fiscal Year: 2010
    ..This proposal will determine whether the presence of two X chromosomes is a risk factor for women and men with Klinefelter's syndrome (47,XXY). ..
  9. Stem Cell-Derived Motoneurons in the Adult Mammalian CNS
    Douglas Kerr; Fiscal Year: 2008
    ..These studies will define an important transplantation approach for motoneuron disease such as ALS and SMA and for spinal cord injury and other spinal disorders. ..
  10. ES Cell-Derived Motoneurons from SMA transgenic mice
    Douglas Kerr; Fiscal Year: 2008
    ..This project will identify critical molecular clues to motoneuron dysfunction in SMA and will identify potential strategies to halt or reverse this dysfunction. ..
  11. 2nd International Pathogenesis of Rare Neuroimmunologic Disorders
    Douglas Kerr; Fiscal Year: 2006
    ..include the following: polymyositis, myasthenia gravis (MG),[unreadable] inflammatory polyneuropathies, transverse myelitis, HTLV-1 associated myelopathy, stiff person syndrome[unreadable] (SPS), neuromyelitis optica (NMO), optic ..
  12. Pathogenesis of Rare Neuroimmunologic Disorders
    Douglas Kerr; Fiscal Year: 2004
    ..There are a variety of rare neuroimmunologic disorders: polymyositis, myasthenia gravis, CIDP, transverse myelitis, TSP/HAM, stiff person syndrome, neuromyelitis optica, optic neuritis, ADEM, PANDAS, Hashimoto's ..
  13. Mentored Patient-Oriented Research Career Development Aw
    David Rizzieri; Fiscal Year: 2004
    ..These results will lead to future improvements in maximizing the anti-tumor effects of allogeneic therapy, hastening immunologic recovery, and minimizing the toxicity of this procedure. ..