rheumatic heart disease

Summary

Summary: The most important manifestation of and sequel to rheumatic fever, i.e., any cardiac involvement in rheumatic fever. (Dorland, 27th ed)

Top Publications

  1. ncbi Molecular mimicry in the autoimmune pathogenesis of rheumatic heart disease
    Luiza Guilherme
    Heart Institute InCor, University of Sao Paulo, School of Medicine, Sao Paulo, Brazil
    Autoimmunity 39:31-9. 2006
  2. ncbi Rheumatic heart disease: mediation by complex immune events
    L Guilherme
    Heart Institute InCor, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil
    Adv Clin Chem 53:31-50. 2011
  3. ncbi The global burden of group A streptococcal diseases
    Jonathan R Carapetis
    Centre for International Child Health, University of Melbourne, Department of Paediatrics and Murdoch Childrens Research Institute, Royal Children s Hospital, Melbourne, Australia
    Lancet Infect Dis 5:685-94. 2005
  4. ncbi Rheumatic heart disease
    Eloi Marijon
    Paris Cardiovascular Research Centre, INSERM U970, European Georges Pompidou Hospital, Paris, France
    Lancet 379:953-64. 2012
  5. ncbi World Heart Federation criteria for echocardiographic diagnosis of rheumatic heart disease--an evidence-based guideline
    Bo Reményi
    Green Lane Pediatric and Congenital Cardiac Service, Starship Children s Hospital, Auckland, New Zealand
    Nat Rev Cardiol 9:297-309. 2012
  6. ncbi Echocardiography screening for rheumatic heart disease in Ugandan schoolchildren
    Andrea Beaton
    Children s National Medical Center, Department of Cardiology, 111 Michigan Ave, Washington, DC 20010, USA
    Circulation 125:3127-32. 2012
  7. ncbi Prevalence of rheumatic heart disease detected by echocardiographic screening
    Eloi Marijon
    Department of Pediatric Cardiology, Hopital Necker Enfants Malades, Paris, France
    N Engl J Med 357:470-6. 2007
  8. ncbi Rheumatic heart disease screening by echocardiography: the inadequacy of World Health Organization criteria for optimizing the diagnosis of subclinical disease
    Eloi Marijon
    Universite Paris Descartes, AP HP, Hopital Europeen Georges Pompidou, France
    Circulation 120:663-8. 2009
  9. ncbi Rheumatic and nonrheumatic valvular heart disease: epidemiology, management, and prevention in Africa
    Mohammed Rafique Essop
    Division of Cardiology, Baragwanath Hospital, University of the Witwatersrand, Johannesburg, South Africa
    Circulation 112:3584-91. 2005
  10. ncbi Incidence and characteristics of newly diagnosed rheumatic heart disease in urban African adults: insights from the heart of Soweto study
    Karen Sliwa
    Soweto Cardiovascular Research Unit, Department of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Bertsham, 2013 Johannesburg, Republic of South Africa
    Eur Heart J 31:719-27. 2010

Detail Information

Publications284 found, 100 shown here

  1. ncbi Molecular mimicry in the autoimmune pathogenesis of rheumatic heart disease
    Luiza Guilherme
    Heart Institute InCor, University of Sao Paulo, School of Medicine, Sao Paulo, Brazil
    Autoimmunity 39:31-9. 2006
    ..the immune response against the group A streptococcus attacks the rheumatic valve leading to chronic rheumatic heart disease. Both B- and T-cell responses are involved in the process, and evidence for the hypotheses of molecular ..
  2. ncbi Rheumatic heart disease: mediation by complex immune events
    L Guilherme
    Heart Institute InCor, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil
    Adv Clin Chem 53:31-50. 2011
    ..b>Rheumatic heart disease (RHD), the most serious complication, occurs in 30-45% of RF patients and leads to chronic valvular ..
  3. ncbi The global burden of group A streptococcal diseases
    Jonathan R Carapetis
    Centre for International Child Health, University of Melbourne, Department of Paediatrics and Murdoch Childrens Research Institute, Royal Children s Hospital, Melbourne, Australia
    Lancet Infect Dis 5:685-94. 2005
    ..that there are at least 517,000 deaths each year due to severe GAS diseases (eg, acute rheumatic fever, rheumatic heart disease, post-streptococcal glomerulonephritis, and invasive infections)...
  4. ncbi Rheumatic heart disease
    Eloi Marijon
    Paris Cardiovascular Research Centre, INSERM U970, European Georges Pompidou Hospital, Paris, France
    Lancet 379:953-64. 2012
    b>Rheumatic heart disease, often neglected by media and policy makers, is a major burden in developing countries where it causes most of the cardiovascular morbidity and mortality in young people, leading to about 250,000 deaths per year ..
  5. ncbi World Heart Federation criteria for echocardiographic diagnosis of rheumatic heart disease--an evidence-based guideline
    Bo Reményi
    Green Lane Pediatric and Congenital Cardiac Service, Starship Children s Hospital, Auckland, New Zealand
    Nat Rev Cardiol 9:297-309. 2012
    Over the past 5 years, the advent of echocardiographic screening for rheumatic heart disease (RHD) has revealed a higher RHD burden than previously thought...
  6. ncbi Echocardiography screening for rheumatic heart disease in Ugandan schoolchildren
    Andrea Beaton
    Children s National Medical Center, Department of Cardiology, 111 Michigan Ave, Washington, DC 20010, USA
    Circulation 125:3127-32. 2012
    Historically, sub-Saharan Africa has had the highest prevalence rates of clinically detected rheumatic heart disease (RHD). Echocardiography-based screening improves detection of RHD in endemic regions...
  7. ncbi Prevalence of rheumatic heart disease detected by echocardiographic screening
    Eloi Marijon
    Department of Pediatric Cardiology, Hopital Necker Enfants Malades, Paris, France
    N Engl J Med 357:470-6. 2007
    Epidemiologic studies of the prevalence of rheumatic heart disease have used clinical screening with echocardiographic confirmation of suspected cases...
  8. ncbi Rheumatic heart disease screening by echocardiography: the inadequacy of World Health Organization criteria for optimizing the diagnosis of subclinical disease
    Eloi Marijon
    Universite Paris Descartes, AP HP, Hopital Europeen Georges Pompidou, France
    Circulation 120:663-8. 2009
    Early case detection is vital in rheumatic heart disease (RHD) in children to minimize the risk of advanced valvular heart disease by preventive measures...
  9. ncbi Rheumatic and nonrheumatic valvular heart disease: epidemiology, management, and prevention in Africa
    Mohammed Rafique Essop
    Division of Cardiology, Baragwanath Hospital, University of the Witwatersrand, Johannesburg, South Africa
    Circulation 112:3584-91. 2005
    ..Acute rheumatic fever and chronic rheumatic valvular disease in their most virulent form are still commonly encountered and impose a huge burden on limited healthcare resources...
  10. ncbi Incidence and characteristics of newly diagnosed rheumatic heart disease in urban African adults: insights from the heart of Soweto study
    Karen Sliwa
    Soweto Cardiovascular Research Unit, Department of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Bertsham, 2013 Johannesburg, Republic of South Africa
    Eur Heart J 31:719-27. 2010
    Little is known on the incidence and clinical characteristics of newly diagnosed rheumatic heart disease (RHD) in adulthood from urban African communities in epidemiologic transition.
  11. pmc Ficolin 2 (FCN2) functional polymorphisms and the risk of rheumatic fever and rheumatic heart disease
    I J Messias-Reason
    Department of Parasitology, Institute of Tropical Medicine, University of Tubingen, 72074 Tubingen, Germany
    Clin Exp Immunol 157:395-9. 2009
    ..pyogenes, which is the aetiological agent of rheumatic fever (RF) and its most severe sequelae, chronic rheumatic heart disease (CRHD)...
  12. pmc Occurrence, aetiology and challenges in the management of congestive heart failure in sub-Saharan Africa: experience of the Cardiac Centre in Shisong, Cameroon
    Jacques Cabral Tantchou Tchoumi
    Cardiac Centre, St Elizabeth Catholic General Hospital Shisong, Cameroon
    Pan Afr Med J 8:11. 2011
    ..The aim of the study was to investigate the occurrence, the aetiology and the management of congestive heart failure in the cardiac centre of the St. Elizabeth catholic general hospital Shisong in Cameroon...
  13. ncbi TGF-beta1 expression and atrial myocardium fibrosis increase in atrial fibrillation secondary to rheumatic heart disease
    Hua Xiao
    Department of Cardiology, First Affiliated Hospital, Chongqing Medical University, Chongqing, China
    Clin Cardiol 33:149-56. 2010
    ..Transforming growth factor-beta1 (TGF-beta1) was one of the main factors for accelerating collagen production. The contribution of TGF-beta1 in the pathogenesis of AF needs further investigation...
  14. pmc The challenges of cardiac surgery for African children
    Ana O H Mocumbi
    Instituto do Coracao, Maputo, Mozambique
    Cardiovasc J Afr 23:165-7. 2012
    ....
  15. ncbi Acute rheumatic fever and rheumatic heart disease in the top end of Australia's Northern Territory
    J R Carapetis
    Menzies School of Health Research, Darwin, Northern Territory, Australia
    Med J Aust 164:146-9. 1996
    To describe the epidemiological and clinical features of acute rheumatic fever and rheumatic heart disease in the Top End of the Northern Territory.
  16. ncbi Is primary prevention of rheumatic fever the missing link in the control of rheumatic heart disease in Africa?
    Ganesan Karthikeyan
    Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada
    Circulation 120:709-13. 2009
    Rheumatic fever and rheumatic heart disease continue to be major public health problems in the developing world, particularly in the countries of sub-Saharan Africa...
  17. ncbi The epidemiological features of heart failure in developing countries: a review of the literature
    G F Mendez
    Cardiac Medicine, National Heart and Lung Institute, Imperial College School of Medicine, Dovehouse Street, London SW3 6LY, UK
    Int J Cardiol 80:213-9. 2001
    ..We review the published data on the epidemiology of heart failure in such countries. Rheumatic heart disease remains a major cause of heart failure in Africa and Asia, especially in the young...
  18. ncbi One year echocardiographic study of rheumatic heart disease at Enugu, Nigeria
    I O Essien
    Department of Medicine, University of Uyo Teaching Hospital, Uyo
    Niger Postgrad Med J 15:175-8. 2008
    b>Rheumatic heart disease is one of the commonest causes of heart disease in Nigeria. Previous studies on rheumatic heart disease in Nigeria were either clinical or retrospective echocardiographic studies...
  19. ncbi Echocardiographic profile of rheumatic heart disease at a tertiary cardiac centre
    Hamza Arslan Aurakzai
    Punjab Institute of Cardiology, Lahore, Pakistan
    J Ayub Med Coll Abbottabad 21:122-6. 2009
    b>Rheumatic Heart Disease (RHD) continues to be a major public health problem in developing countries like Pakistan...
  20. doi Time to use ultrasound and not stethoscopes for rheumatic heart disease screening
    Eloi Marijon
    Departement de Cardiologie, Hopital Europeen Georges Pompidou, 20 rue Leblanc, 75908 Paris Cedex 15, France
    Nat Clin Pract Cardiovasc Med 5:E1-3. 2008
  21. pmc Echocardiographic screening for rheumatic heart disease
    Eloi Marijon
    Bull World Health Organ 86:84. 2008
  22. pmc Prevalence and pattern of rheumatic heart disease in the Nigerian savannah: an echocardiographic study
    M U Sani
    Department of Medicine, Aminu Kano Teaching Hospital, Kano, Nigeria
    Cardiovasc J Afr 18:295-9. 2007
    b>Rheumatic heart disease (RHD) remains a major public health problem in developing countries. Whereas Africa has 10% of the world's population, as many as half of the 2.4 million children affected by RHD globally live on the continent...
  23. ncbi Systematic Review: Estimation of global burden of non-suppurative sequelae of upper respiratory tract infection: rheumatic fever and post-streptococcal glomerulonephritis
    Stewart J Jackson
    Centre for Population Sciences, University of Edinburgh, Edinburgh, UK
    Trop Med Int Health 16:2-11. 2011
    To establish the incidence of post-streptococcal glomerulonephritis (PSGN) and acute rheumatic fever, the prevalence of rheumatic heart disease (RHD), and to estimate morbidity and mortality caused by these diseases globally.
  24. ncbi Rheumatic valvulopathies occurence, pattern and follow-up in rural area: the experience of the Shisong Hospital, Cameroon
    J C Tantchou Tchoumi
    St Elizabeth Catholic General Hospital, Shisong, P O Box 8 Kumbo, Cameroun
    Bull Soc Pathol Exot 102:155-8. 2009
    b>Rheumatic heart disease (RHD) remains a major public health problem in developing countries. Whereas Africa has 10% of the world's population, broadly as many as half of the 2.4 million children affected by RHD live on the continent...
  25. pmc Congenital heart disease and rheumatic heart disease in Africa: recent advances and current priorities
    Liesl Zuhlke
    Department of Paediatrics, Red Cross War Memorial Children s Hospital and University of Cape Town, Cape Town, South Africa
    Heart 99:1554-61. 2013
    ..prevalence of heart diseases in children and young adults, including congenital heart disease (CHD) and rheumatic heart disease (RHD)...
  26. ncbi Prevention and treatment of rheumatic heart disease in the developing world
    Andrew C Steer
    Centre for International Child Health, University of Melbourne, Parkville, VIC 3052, Australia
    Nat Rev Cardiol 6:689-98. 2009
    The prevalence of rheumatic heart disease (RHD) in industrialized countries has declined dramatically over the last century, but the disease remains an important global health problem with the burden of disease shouldered by developing ..
  27. ncbi The role of HLA molecules in susceptibility to chronic rheumatic heart disease
    H Kudat
    Department of Cardiology, Istanbul Faculty of Medicine, Istanbul University, Capa, Istanbul, Turkey
    Int J Immunogenet 33:41-4. 2006
    ..and a general consensus on the relation between human leucocyte antigen (HLA) class II antigens and rheumatic heart disease (RHD), the details and the culprit antigens are still controversial...
  28. ncbi Echocardiographic patterns of juvenile rheumatic heart disease at the Kenyatta National Hospital, Nairobi
    C Yuko-Jowi
    Department of Paediatrics and Child Health, College of Health Sciences, University of Nairobi, P O Box 19676 00202 Nairobi, Kenya
    East Afr Med J 82:514-9. 2005
    To describe the echocardiographic features of children with rheumatic heart disease seen at the Kenyatta National Hospital.
  29. ncbi Features of acute ischemic stroke with rheumatic heart disease in a hospitalized Chinese population
    Deren Wang
    Stroke Clinical Research Unit, Department of Neurology, West China Hospital, State Key Laboratory of Biotherapy and Cancer Center, Sichuan University, No 37, Guo Xue Xiang, Chengdu, 610041, Sichuan Province, PR China
    Stroke 43:2853-7. 2012
    b>Rheumatic heart disease (RHD) is an important risk factor for ischemic stroke in developing countries. Observational data on its characteristics and influence on outcome or recurrence of ischemic stroke are scarce...
  30. ncbi Echocardiographic screening for subclinical rheumatic heart disease remains a research tool pending studies of impact on prognosis
    Liesl Zuhlke
    Division of Paediatric Cardiology, Red Cross War Memorial Children s Hospital and University of Cape Town, Cape Town, South Africa
    Curr Cardiol Rep 15:343. 2013
    ..The application of portable echocardiography to the screening of asymptomatic children and young adults for rheumatic heart disease (RHD) in developing countries indicates that the disease may affect 62 million to 78 million individuals ..
  31. ncbi Clinical spectrum of chronic rheumatic heart disease in India
    Anand Chockalingam
    Department of Cardiology, Madras Medical College and Research Institute, Chennai, India
    J Heart Valve Dis 12:577-81. 2003
    The study aim was to determine prevalence and patterns of chronic rheumatic heart disease (RHD) in developing countries, where it remains a major cause of mortality and morbidity...
  32. ncbi Rationale and design of a Global Rheumatic Heart Disease Registry: the REMEDY study
    Ganesan Karthikeyan
    Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India
    Am Heart J 163:535-40.e1. 2012
    b>Rheumatic heart disease (RHD) is the principal cause of valvular heart disease-related mortality and morbidity in low- and middle-income countries. The disease predominantly affects children and young adults...
  33. ncbi Priming the immune system for heart disease: a perspective on group A streptococci
    Nadia M J Ellis
    Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    J Infect Dis 202:1059-67. 2010
    ....
  34. pmc Prospective comparison of clinical and echocardiographic diagnosis of rheumatic carditis: long term follow up of patients with subclinical disease
    F E Figueroa
    Facultad de Medicina, Universidad de Los Andes, Avenida San Carlos de Apoquindo 2200, Santiago de Chile, Chile
    Heart 85:407-10. 2001
    ..To determine the frequency of occurrence and long term evolution of subclinical carditis in patients with acute rheumatic fever...
  35. ncbi Mortality due to acute rheumatic fever and rheumatic heart disease in the Northern Territory: a preventable cause of death in aboriginal people
    J R Carapetis
    Menzies School of Health Research, Northern Territory
    Aust N Z J Public Health 23:159-63. 1999
    To determine the death rates and effect on premature mortality in the Northern Territory of acute rheumatic fever and rheumatic heart disease.
  36. ncbi Progression of isolated tricuspid regurgitation late after mitral valve surgery for rheumatic mitral valve disease
    Chisato Izumi
    Department of Cardiology, Tenri Hospital, Nara, Japan
    J Heart Valve Dis 11:353-6. 2002
    ..The study aim was to investigate severe isolated TR late after mitral valve surgery for rheumatic mitral valve disease...
  37. ncbi Prevalence of rheumatic heart disease in school children in Bikaner: an echocardiographic study
    K L Periwal
    Department of Pediatrics, SP Medical College and Associated Group of Hospitals, Bikaner, India
    J Assoc Physicians India 54:279-82. 2006
    To determine prevalence of rheumatic heart disease (RHD) using clinical and echocardiographic criteria and to study influence of socioeconomic status (SES) we studied school children in a north-western Indian town.
  38. ncbi Rheumatic fever and rheumatic heart disease: clinical profile of 550 cases in India
    M S Ravisha
    Department of Pediatrics, Seth G S Medical College and KEM Hospital, Parel, Mumbai, Maharashtra, India
    Arch Med Res 34:382-7. 2003
    ..of this paper were to analyze the clinical presentation of children with rheumatic fever (RF) and rheumatic heart disease (RHD), to determine the cardiac sequel of RF and valvular affection due to RF, and to study clinical ..
  39. ncbi Prevalence of rheumatic heart disease: has it declined in India?
    S Ramakrishnan
    Department of Cardiology, All India Institute of Medical Sciences, New Delhi 110029, India
    Natl Med J India 22:72-4. 2009
    b>Rheumatic heart disease continues to be a major health problem in many parts of the world...
  40. ncbi The Drakensberg declaration on the control of rheumatic fever and rheumatic heart disease in Africa
    Bongani Mayosi
    University of Cape Town, South Africa
    S Afr Med J 96:246. 2006
  41. ncbi Evaluation of a screening protocol using auscultation and portable echocardiography to detect asymptomatic rheumatic heart disease in Tongan schoolchildren
    Jonathan R Carapetis
    Menzies School of Health Research, Charles Darwin University, Darwin, Australia
    Nat Clin Pract Cardiovasc Med 5:411-7. 2008
    b>Rheumatic heart disease (RHD) is an important problem in developing countries; however, many cases are detected only when the disease has progressed to cardiac failure...
  42. ncbi Rheumatic heart disease and its control in the Pacific
    Samantha M Colquhoun
    Menzies School of Health Research, Charles Darwin University, Darwin, Australia
    Expert Rev Cardiovasc Ther 7:1517-24. 2009
    Rheumatic fever and rheumatic heart disease continue to be a huge public-health burden on many Pacific Island countries...
  43. pmc Epidemiology of rheumatic fever and rheumatic heart disease in a rural community in northern India
    A Grover
    Post Graduate Institute of Medical Education and Research, Chandigarh, India
    Bull World Health Organ 71:59-66. 1993
    The epidemiology of rheumatic fever and rheumatic heart disease in a rural community (total population 114,610) in northern India was studied by setting up a registry based on primary health care centres...
  44. ncbi High incidence of rheumatic fever and rheumatic heart disease in the republics of Central Asia
    Nazgul A Omurzakova
    Institute of Medical Science, St Marianna University, Kawasaki, Japan
    Int J Rheum Dis 12:79-83. 2009
    The epidemiological situation involving rheumatic fever (RF) and rheumatic heart disease (RHD) not only remains unresolved but is also a cause of serious concern due to the rapid increase in the incidence of RF/RHD in many developing ..
  45. ncbi Rheumatic heart disease in Ethiopia: could it be more malignant?
    Kebede Oli
    Department of Internal Medicine, Tikur Anbessa Hospital, Addis Ababa, Ethiopia
    Ethiop Med J 42:1-8. 2004
    ..Factors responsible for rapid course in an Ethiopian need to be addressed urgently...
  46. pmc Prevention and control of rheumatic fever and rheumatic heart disease: the Cuban experience (1986-1996-2002)
    P Nordet
    World Health Organisation, Geneva, Switzerland
    Cardiovasc J Afr 19:135-40. 2008
    Rheumatic fever (RF) and rheumatic heart disease (RHD) are still major medical and public health problems mainly in developing countries...
  47. ncbi Assessment of a register-based rheumatic heart disease secondary prevention program in an Australian Aboriginal community
    Sabry Eissa
    Royal Free and University College London Medical School, University College London, United Kingdom
    Aust N Z J Public Health 29:521-5. 2005
    To assess specific performance indicators relating to a register-based acute rheumatic fever and rheumatic heart disease (ARF/RHD) prevention program in a remote Australian Aboriginal community in order to identify the most appropriate ..
  48. ncbi Declining prevalence of rheumatic heart disease in rural schoolchildren in India: 2001-2002
    V Jacob Jose
    Department of Cardiology, Christian Medical College and Hospital, Vellore
    Indian Heart J 55:158-60. 2003
    b>Rheumatic heart disease is still a major health problem in developing countries such as India and, for the health planners to allocate funds, the actual prevalence of the disease should be known...
  49. ncbi Pathogenic mechanisms in rheumatic carditis: focus on valvular endothelium
    S Roberts
    Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    J Infect Dis 183:507-11. 2001
    To clarify immune-mediated mechanisms in rheumatic heart disease caused by group A streptococcal infection, valve tissues from rheumatic patients with valvular heart disease who required valve replacement were studied for reactivity with ..
  50. ncbi PDIA3, HSPA5 and vimentin, proteins identified by 2-DE in the valvular tissue, are the target antigens of peripheral and heart infiltrating T cells from chronic rheumatic heart disease patients
    Kellen C Fae
    Heart Institute InCor, University of Sao Paulo, Sao Paulo, Brazil
    J Autoimmun 31:136-41. 2008
    ..b>Rheumatic heart disease (RHD), the major manifestation of RF, is characterized by inflammation of heart valves and myocardium...
  51. ncbi Pregnancy in women with heart disease in sub-Saharan Africa
    Maboury Diao
    Service de cardiologie, CHU Aristide Le Dantec, Faculté de Médecine de Dakar, BP 6633, Dakar Etoile, Senegal
    Arch Cardiovasc Dis 104:370-4. 2011
    ..Although previous studies showed that pregnancy with heart disease is associated with significant complications, few focused on patients with valvular heart disease in sub-Saharan Africa...
  52. pmc Pattern of heart failure in a Nigerian teaching hospital
    Arthur C Onwuchekwa
    Department of Internal Medicine, University of Port Harcourt Teaching Hospital, Port Harcourt, Rivers State, Nigeria
    Vasc Health Risk Manag 5:745-50. 2009
    ..Congestive cardiac failure (CCF) has emerged as a major public health problem worldwide and imposes an escalating burden on the health care system...
  53. ncbi Detection of nanobacteria-like material from calcified cardiac valves with rheumatic heart disease
    Ye Rong Hu
    Department of Cardiothoracic Surgery, Second Xiang Ya Hospital, Central South University, Changsha, Hunan 410011, China
    Cardiovasc Pathol 19:286-92. 2010
    ..Pathological calcification is also present in cardiac valves with rheumatic heart disease. The aim of this study was to detect, isolate, culture, and characterize nanobacteria-like material from ..
  54. ncbi Mimicry in recognition of cardiac myosin peptides by heart-intralesional T cell clones from rheumatic heart disease
    Kellen C Fae
    Heart Institute Instituto do Coração University of São Paulo, School of Medicine, Avenida Dr Eneas de Carvalho Aguiar, 44 9o andar, 05403 000 Sao Paulo, Brazil
    J Immunol 176:5662-70. 2006
    ..human proteins has been considered as a mechanism leading to autoimmune reactions in rheumatic fever and rheumatic heart disease (RHD)...
  55. ncbi High prevalence of rheumatic heart disease detected by echocardiography in school children
    Maneesha Bhaya
    Sardar Patel Medical College and Associated Group of Hospitals, Department of Cardiology, Bikaner, Rajasthan, India
    Echocardiography 27:448-53. 2010
    It is fairly easy to detect advanced valve lesions of established rheumatic heart disease by echocardiography in the clinically identified cases of rheumatic heart disease...
  56. ncbi Serum cardiac troponin-I in active rheumatic carditis
    B Oran
    Department of Pediatrics, School of Medicine, Selcuk University, Konya, Turkey
    Indian J Pediatr 68:943-4. 2001
    ..The study was performed to investigate the level of serum cardiac troponin I (cTnI), a specific marker for myocardial cell damage, in the acute rheumatic carditis (RC)...
  57. ncbi Pathology and pathogenesis of rheumatic heart disease
    P Chopra
    Department of Pathology, Sir Ganga Ram Hospital, New Delhi
    Indian J Pathol Microbiol 50:685-97. 2007
    Cardiovascular disease is on the rise. In India and other developing countries, rheumatic heart disease (RHD) continues to be a major public health problem and contributes to significant cardiac morbidity and mortality...
  58. ncbi Prevalence of rheumatic fever and rheumatic heart disease in rural Bangladesh
    Jasimuddin Ahmed
    National Center for Control of Rheumatic Fever and Heart Diseases, Sher E Bangla Nagar, Dhaka, Bangladesh
    Trop Doct 35:160-1. 2005
    ..5923 rural Bangladeshi children aged 5-15 years to determine the prevalence of rheumatic fever (RF) and rheumatic heart disease (RHD). The prevalence was found to be 1.2 (95% confidence interval 0.3-2...
  59. ncbi Rheumatic fever and rheumatic heart disease: genetics and pathogenesis
    L Guilherme
    Heart Institute InCor, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil
    Scand J Immunol 66:199-207. 2007
    ..human proteins is considered as the triggering factor leading to autoimmunity in rheumatic fever (RF) and rheumatic heart disease (RHD)...
  60. ncbi Frequency of severe mitral stenosis in young female patients having pure mitral stenosis secondary to rheumatic heart disease
    Shakeel Ahmad
    Department of Cardiology, Ayub Medical College, Abbottabad, Pakistan
    J Ayub Med Coll Abbottabad 22:19-22. 2010
    High morbidity and mortality due to Rheumatic heart disease (RHD) associated with females is mainly because of late diagnosis on one hand and socioeconomic reasons on the other hand...
  61. pmc The state of heart disease in Sudan
    A Suliman
    Department of Medicine, University of Khartoum, Khartoum, Sudan
    Cardiovasc J Afr 22:191-6. 2011
    ..In Africa, the burden of CVD is increasing rapidly and it is now a public health concern. Epidemiological data on diseases is scarce and fragmented on the continent...
  62. ncbi Primary triple valve surgery for advanced rheumatic heart disease in Mainland China: a single-center experience with 871 clinical cases
    Qing qi Han
    Department of Cardiothoracic Surgery, Changhai Hospital, Second Military Medical University, Shanghai, People s Republic of China
    Eur J Cardiothorac Surg 31:845-50. 2007
    Triple valve surgery (TVS) is still of choice for advanced rheumatic heart disease (RHD), which has been associated with reported poor early and late outcomes...
  63. pmc Autoantibodies in the sera of patients with rheumatic heart disease: characterization of myocardial antigens by two-dimensional immunoblotting and N-terminal sequence analysis
    D Tontsch
    Department of Internal Medicine Cardiology, Philipps University of Marburg, Marburg, Germany
    Clin Exp Immunol 121:270-4. 2000
    ..and the range of cross-reactive tissue antigens for streptococcal-induced antibodies identified in rheumatic heart disease is still expanding...
  64. ncbi High prevalence of subclinical rheumatic heart disease in pregnant women in a developing country: an echocardiographic study
    Håvard Otto
    Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway
    Echocardiography 28:1049-53. 2011
    Pregnant women with rheumatic heart disease (RHD) carry a high risk of morbidity and mortality. In this study the prevalence of subclinical RHD in pregnant women in Keren, Eritrea was assessed using echocardiography.
  65. ncbi Ongoing inflammation in children with rheumatic heart disease
    Nevin M M Habeeb
    Pediatric Cardiology Department and Clinical Pathology Department, Ain Shams University, 15 A Saraya Al Kobba Square, Cairo, Egypt
    Cardiol Young 21:334-9. 2011
    To elucidate the hypothesis of ongoing inflammation in children with chronic rheumatic heart disease, and its possible consequences.
  66. ncbi Surgical challenges in rheumatic heart disease in the Australian indigenous population
    Ali M Alizzi
    Department of Cardiothoracic Surgery, Flinders Medical Centre, Bedford Park, Adelaide, SA, Australia
    Heart Lung Circ 19:295-8. 2010
    Acute rheumatic fever, leading to rheumatic heart disease (RHD), is rare in Australia except amongst Aboriginal and Torres Strait Islander people.
  67. ncbi Stroke and rheumatic heart disease: a systematic review of observational studies
    Deren Wang
    Stroke Clinical Research Unit, Department of Neurology, West China Hospital, Sichuan University, Chengdu 610041, China
    Clin Neurol Neurosurg 115:1575-82. 2013
    Ischemic stroke is a severe complication of rheumatic heart disease (RHD), but data about its incidence and case-fatality in RHD patients' population is unclear...
  68. ncbi Mitral valve repair versus replacement in patients with rheumatic heart disease
    Zhenhua Wang
    Department of Surgery, State Key Laboratory of Cardiovascular Disease, Fu Wai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People s Republic of China
    J Heart Valve Dis 22:333-9. 2013
    Rheumatic fever is still the main cause of valve disease in developing countries. The study aim was to investigate the appropriateness of mitral valve repair in adult patients with rheumatic heart disease (RHD).
  69. ncbi Acute rheumatic fever and its consequences: a persistent threat to developing nations in the 21st century
    Jennifer L Lee
    Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis School of Medicine, Suite 6510, Davis, CA 95616, USA
    Autoimmun Rev 9:117-23. 2009
    ..The major source of morbidity and mortality of ARF stems from rheumatic heart disease (RHD), although the cardinal symptoms of the disease also include polyarthritis, Sydenham's chorea, ..
  70. ncbi Apparent contrasting rates of pharyngitis and pyoderma in regions where rheumatic heart disease is highly prevalent
    Malcolm McDonald
    Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia
    Heart Lung Circ 16:254-9. 2007
    ..was to describe the epidemiology of pharyngitis and pyoderma in a Central Australian Aboriginal community with a high prevalence of rheumatic heart disease (RHD) and compare it to communities in the Top End of the Northern Territory.
  71. ncbi Maternal and perinatal outcome in rheumatic heart disease
    H Sawhney
    Department of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Int J Gynaecol Obstet 80:9-14. 2003
    To study the maternal and perinatal outcome of pregnancies complicated by rheumatic heart disease.
  72. ncbi Adhesion molecule expression and ventricular remodeling in chronic rheumatic heart disease: a cause or effect in the disease progression--a pilot study
    Uma Nahar Saikia
    Department of Histopathology PGIMER, Chandigarh, India
    Cardiovasc Pathol 21:83-8. 2012
    Rheumatic fever and chronic rheumatic heart disease (RHD) remains one of the most important causes of cardiovascular morbidity leading to a major public health problem, especially in developing countries...
  73. ncbi The value of echocardiography in the diagnosis and followup of rheumatic carditis in children and adolescents: a 2 year prospective study
    M O Hilario
    Department of Pediatrics, Universidade Federal de Sao Paulo, Brazil
    J Rheumatol 27:1082-6. 2000
    ..To evaluate echocardiographic/Doppler findings in patients with rheumatic fever whether or not clinical manifestations of carditis were present, and the followup of these findings 24 months after the acute phase...
  74. ncbi Percutaneous transvenous mitral commissurotomy in patients with severe mitral stenosis and acute rheumatic fever
    S S Kothari
    Department of Cardiology, All India Institute of Medical Sciences, New Delhi, 110029, India
    Pediatr Cardiol 27:347-50. 2006
    ..PTMC can be performed in children with ARF without an increase in procedural complications. However, the restenosis rates appear to be higher...
  75. ncbi Serum cardiac troponin I in acute rheumatic fever
    Monesha Gupta
    Division of Pediatric Cardiology, New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, New York, USA
    Am J Cardiol 89:779-82. 2002
  76. ncbi Subclinical carditis in rheumatic fever: a systematic review
    Marissa Tubridy-Clark
    Centre for International Child Health, University of Melbourne, Melbourne, Australia
    Int J Cardiol 119:54-8. 2007
    ..We aimed to review the existing literature on the prevalence and outcome of SCC in ARF...
  77. ncbi Intermediate-term results of percutaneous transvenous mitral commissurotomy in children less than 12 years of age
    Shyam S Kothari
    Department of Cardiology, All India Institute of Medical Sciences, New Delhi
    Catheter Cardiovasc Interv 64:487-90. 2005
    ..4% 8.7%. PTMC provides excellent intermediate-term palliation even in young children with rheumatic mitral stenosis...
  78. ncbi Patient views on the management of rheumatic fever and rheumatic heart disease in the Kimberley: a qualitative study
    Christine M Mincham
    School of Population Health, The University of Western Australia, Perth, Western Australia, Australia
    Aust J Rural Health 11:260-5. 2003
    To describe, from a patient perspective, factors leading to suboptimal management of individuals with rheumatic fever (RF) and rheumatic heart disease (RHD) among members of the Kimberley population.
  79. ncbi Enterovirus replication in valvular tissue from patients with chronic rheumatic heart disease
    Y Li
    Cell and Molecular Biology Section, Imperial College School of Medicine, London, UK
    Eur Heart J 23:567-73. 2002
    To investigate the involvement of enterovirus infection in chronic, rheumatic heart disease.
  80. ncbi Association of tumor necrosis factor-alpha polymorphisms with susceptibility and clinical outcomes of rheumatic heart disease
    Amal A Mohamed
    Department of Clinical and Chemical Pathology, Faculty of Medicine, Cairo University 11562, Cairo, Egypt amal_abd_elwahab yahoo com
    Saudi Med J 31:644-9. 2010
    To examine the association of tumor necrosis factor-alpha (TNF-alpha) gene polymorphisms with rheumatic heart disease (RHD) and valve damage, and their influence on TNF-alpha production and disease outcome.
  81. ncbi Rheumatic heart disease detected by echocardiographic screening
    Rachel Webb
    N Engl J Med 357:2088; author reply 2088-9. 2007
  82. ncbi No association of PTPN22 R620W gene polymorphism with rheumatic heart disease and systemic lupus erythematosus
    Rahime Aksoy
    Department of Immunology and Allergy diseases, Faculty of Medicine, Ankara University, Ankara, Turkey
    Mol Biol Rep 38:5393-6. 2011
    b>Rheumatic heart disease (RHD) or acute rheumatic fever (ARF) develops as a consequence of an exaggerated immune response to Group A beta haemolytic streptococci causing pharyngitis...
  83. ncbi Long term follow-up results of 139 Turkish children and adolescents with rheumatic heart disease
    Taner Yavuz
    Department of Paediatrics, Faculty of Medicine, University of Duzce, Konuralp, Duzce, Turkey
    Eur J Pediatr 167:1321-6. 2008
    ..020). In conclusion, the initial severity of valve involvement and the presence of CMAR at initial attack were found to be the best predictors for the severity of chronic rheumatic valvar disease in this study...
  84. ncbi Rheumatic heart disease in indigenous populations
    Harvey White
    Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
    Heart Lung Circ 19:273-81. 2010
    Rates of acute rheumatic fever and chronic rheumatic heart disease in Aboriginal people, Torres Strait Islanders and Māori continue to be unacceptably high...
  85. ncbi Pattern of rheumatic heart disease in Southern Yemen
    Hussein K Saleh
    Internal Medicine Department, Faculty of Medicine and Health Sciences, University of Aden, Aden, Yemen
    Saudi Med J 28:108-13. 2007
    To determine the pattern of rheumatic heart disease in Aden city and surrounding areas by assessing its frequency distribution, severity and complications.
  86. ncbi Environmental factors and rheumatic heart disease in Fiji
    Joelle Dobson
    St George s University of London, London, UK
    Pediatr Cardiol 33:332-6. 2012
    b>Rheumatic heart disease (RHD) is an important cause of cardiac morbidity and mortality globally, particularly in the Pacific region...
  87. ncbi Prevalence and outcome of subclinical rheumatic heart disease in India: the RHEUMATIC (Rheumatic Heart Echo Utilisation and Monitoring Actuarial Trends in Indian Children) study
    Anita Saxena
    Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India
    Heart 97:2018-22. 2011
    To study the prevalence and medium term outcome of subclinical rheumatic heart disease (RHD) in India.
  88. ncbi Antigenic complementarity between coxsackie virus and streptococcus in the induction of rheumatic heart disease and autoimmune myocarditis
    Robert Root-Bernstein
    Department of Physiology, Michigan State University, East Lansing, MI 48824, USA
    Autoimmunity 42:1-16. 2009
    A variety of clinical, epidemiological, and experimental data suggest that rheumatic heart disease and autoimmune myocarditis are not only similar in their pathogenesis, but may often be due to combined infections with coxsackie virus (..
  89. ncbi Ross procedure in rheumatic aortic valve disease
    Arkalgud Sampath Kumar
    Cardiothoracic Centre, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, India
    Eur J Cardiothorac Surg 29:156-61. 2006
    To assess the results of aortic valve replacement with the pulmonary autograft in patients with rheumatic heart disease.
  90. ncbi Valve repair in rheumatic heart disease in pediatric age group
    Pramod K Reddy
    Department of Pediatric Cardiac Surgery Apollo Children s Heart Hospital Hyderabad, India
    Asian Cardiovasc Thorac Ann 16:129-33. 2008
    ..From April 2004 to September 2005, 1 boy and 8 girls with rheumatic heart disease, aged 2-13 years (median, 9 years), underwent valve repair for isolated mitral regurgitation in 5, ..
  91. ncbi Acute rheumatic fever and rheumatic heart disease--priorities in prevention, diagnosis and management. A report of the CSANZ Indigenous Cardiovascular Health Conference, Alice Springs 2011
    M G W Rémond
    Cairns Clinical School, School of Medicine and Dentistry, James Cook University, Cairns, Australia
    Heart Lung Circ 21:632-8. 2012
    Three priority areas in the prevention, diagnosis and management of acute rheumatic fever (ARF) and rheumatic heart disease (RHD) were identified and discussed in detail: 1...
  92. ncbi [Prevalence of coronary artery disease in patients with rheumatic heart disease in China]
    Bai Ling Li
    Department of Cardiothoracic Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
    Zhonghua Yi Xue Za Zhi 87:3313-6. 2007
    To investigate the prevalence of coronary artery disease (CAD) and the atherosclerotic risk factors in the patients undergoing valvular surgery due to rheumatic heart disease.
  93. ncbi Infective endocarditis and rheumatic heart disease in the north of Australia
    Catherine A Baskerville
    Division of Medicine, Cairns Base Hospital, The Esplanade, Cairns, QLD, 4870, Australia
    Heart Lung Circ 21:36-41. 2012
    ..IE), Australian guidelines recommend providing prophylactic antibiotics to Indigenous patients with rheumatic heart disease (RHD) prior to procedures which may cause bacteremia. In northern Australia RHD remains prevalent...
  94. ncbi Rheumatic fever and rheumatic heart disease: primary prevention is the cost effective option
    James Irlam
    Indian J Pediatr 75:86; author reply 86-7. 2008
  95. ncbi Outcome of significant functional tricuspid regurgitation late after mitral valve replacement for predominant rheumatic mitral stenosis
    Ayca Boyaci
    Turkiye Yuksek Ihtisas Hospital, Department of Cardiology, Ankara, Turkey
    Angiology 58:336-42. 2007
    ..Therefore, further studies are needed to evaluate the effect of concomitant tricuspid valve repair on the late outcome of patients undergoing mitral valve surgery in order to prevent significant late morbidity...
  96. ncbi Optimising echocardiographic screening for rheumatic heart disease in New Zealand: not all valve disease is rheumatic
    Rachel H Webb
    Green Lane Paediatric and Congenital Cardiology Department, Starship Children s Hospital, Auckland, New Zealand
    Cardiol Young 21:436-43. 2011
    Echocardiography detects a greater prevalence of rheumatic heart disease than heart auscultation...
  97. ncbi Rheumatic heart disease in developing countries
    Stanford T Shulman
    N Engl J Med 357:2089; author reply 2089. 2007
  98. ncbi Which patient undergoing mitral valve surgery should also have the tricuspid repair?
    Giacomo Bianchi
    Department of Adult Cardiac Surgery, Heart Hospital G Monasterio Foundation, Massa, Italy
    Interact Cardiovasc Thorac Surg 9:1009-20. 2009
    ..Annuloplasty ring repair has better outcome compared with non-ring based repair techniques; the beneficial effect is also independent of the type of mitral valve surgery performed...
  99. ncbi Functional tricuspid regurgitation in rheumatic heart disease: surgical options
    Mumraiz Salik Naqshband
    Department of Research, CME, Lahore, Pakistan
    Ann Thorac Cardiovasc Surg 16:417-25. 2010
    ....
  100. ncbi Prevalence of chronic rheumatic heart disease in Chinese adults
    Wang Zhimin
    Department of Echocardiography, Fu Wai Hospital and Cardiovascular Institute, Chinese Academy of Medical Sciences, Beijing 100037, PR China
    Int J Cardiol 107:356-9. 2006
    b>Rheumatic heart disease continues to be a common health problem in the developing countries...
  101. ncbi Prevalence of rheumatic heart disease in school children of urban Lahore
    M Sadiq
    Department of Paediatric Cardiology, Punjab Institute of Cardiology, Lahore, Pakistan
    Heart 95:353-7. 2009
    To determine the prevalence of rheumatic heart disease (RHD) among school children in urban and semiurban areas of Lahore, Pakistan.

Research Grants21

  1. Hypoplastic Left Heart Syndrome: Expression of RHD in the Fetus?
    Pirooz Eghtesady; Fiscal Year: 2013
    ..The goal of this proposal is to test a novel hypothesis that states HLHS is an expression of rheumatic heart disease (RHD) in the fetus...
  2. PLASMINOGEN AND PLASMIN: STRUCTURE AND FUNCTION
    Francis J Castellino; Fiscal Year: 2013
    ..g., rheumatic heart disease, streptococcal toxic shock syndrome, and necrotic fasciitis...
  3. Host-pathogen signaling in group A streptococcal infection
    Michael R Wessels; Fiscal Year: 2012
    ..pyogenes or GAS) accounts for an estimated 500,000 deaths per year primarily from complications of rheumatic heart disease, a postinfectious sequel of GAS infection, and from invasive GAS infections...
  4. Tissue-Specific Infection by Group A Streptococci
    DEBRA BESSEN; Fiscal Year: 2009
    ..of transmission of GAS will result in a decreased burden of the more severe GAS diseases (toxic shock syndrome, rheumatic heart disease) which have a high morbidity and mortality for many people throughout the world.
  5. Factors that influence susceptibility to acute streptococcal pharyngitis
    Patricia A Ryan; Fiscal Year: 2012
    ..million cases of pharyngitis occur worldwide annually, and that 3 million children currently suffer from rheumatic heart disease as a result of improper treatment of these infections, identifying factors that increase or decrease a ..
  6. Developing an animal model of HLHS: role of immune mediated injury
    Pirooz Eghtesady; Fiscal Year: 2012
    ..Our hypothesis is that HLHS is an expression of a form of rheumatic heart disease (RHD) in the fetus...
  7. Vaccine Prevention of Group A Streptococcal Infections
    James B Dale; Fiscal Year: 2013
    ..group A streptococcal (GAS) infections and their most serious complications, acute rheumatic fever (ARF), rheumatic heart disease (RHD) and invasive disease...
  8. Heme Acquisition in Group A Streptococcus
    Benfang Lei; Fiscal Year: 2005
    ..cellulitis, scarlet fever, necrotizing fasciitis, toxic shock syndrome, acute rheumatic fever, rheumatic heart disease, and glomerulonephritis...
  9. Linked: Novel Education Clincial Trainees and Researchers (NECTAR) program
    James Gita Hakim; Fiscal Year: 2013
    ..Zimbabwe and provide opportunities to enhance students'educational program broadly: heart failure, rheumatic heart disease, and hypertension/stroke...
  10. ALKALOID SYNTHESIS VIA (3+2) CYCLOADDITIONS
    BRIAN COPPOLA; Fiscal Year: 2003
    ..and antiretroviral agents, (5) scandine, a component of a Chinese folk medicine used for the treatment of rheumatic heart disease, and (6) erycibelline, a member of the tropane class of alkaloids...
  11. Streptococcal pharyngitis in slum versus non-slum communities in Salvador Brazil
    SARA TARTOF; Fiscal Year: 2007
    ..applicant): Streptococcal pharyngitis is the acute disease that precedes the chronic disease process of rheumatic heart disease (RHD)...
  12. RNA Polymerase Sigma Factors in Streptococcus pyogenes
    CHARLES MORAN; Fiscal Year: 2005
    ..self-limiting skin and throat infections, with, however, the potential for serious sequelae including rheumatic heart disease, acute glomerulonephritis, and possibly pediatric neuropsychological disorders, to severe invasive ..
  13. NIH - BOSTON AREA ANTICOAGULATION TRIAL FOR ATRIAL FIBRI
    J Kistler; Fiscal Year: 1991
    ..of oral anticoagulant therapy in reducing embolic stroke and systemic emboli in patients with AF, without rheumatic heart disease. The benefits and risks of anticoagulation will be evaluated by a randomized, controlled trial assigning ..
  14. MYOSIN--A LINK BETWEEN STREPTOCOCCI AND HEART
    Madeleine Cunningham; Fiscal Year: 2008
    ..r37 ..
  15. Autoimmune Determinants of Human Cardiac Myosin
    Madeleine Cunningham; Fiscal Year: 2008
    ..Our work will provide a better understanding of pathogenic and protective immune mechanisms in animal models of myocarditis and cardiomyopathy and their relationship to human disease. ..
  16. Osteoblastogenesis in Aortic Valve Calcification
    Nalini Rajamannan; Fiscal Year: 2006
    ..If hypercholesterolemia stimulates the development of calcification in the aortic valve then the use of medical therapy such as HMG CoA reductase medications may have a role in the medical therapy of calcific aortic stenosis. ..
  17. Molecular Imaging of Cardiac Cell Transplantation
    Joseph Wu; Fiscal Year: 2008
    ..The goal is to use molecular imaging to guide stem cell therapy, which should translate into transplant protocols that are more reproducible, quantifiable, and beneficial. ..
  18. Nanostructuring and Molecular Imaging of Engineered Cardiovascular Tissues
    Joseph Wu; Fiscal Year: 2008
    ..With a multi-disciplinary team approach, we are confident that these combined efforts will accelerate the translation of nanotechnology-based tissue engineering to the clinical arena in the future. ..