steatorrhea

Summary

Summary: A condition that is characterized by chronic fatty DIARRHEA, a result of abnormal DIGESTION and/or INTESTINAL ABSORPTION of FATS.

Top Publications

  1. ncbi [Intestinal lymphoid nodular hyperplasia in a patient with acquired dysgammaglobulinemia, chronic diarrhea, and bacterial overgrowth syndrome]
    B Castañeda-Romero
    Departamento de Gastroenterologia, Instituto Nacional de la Nutricion Salvador Zubiran, Mexico, DF
    Rev Gastroenterol Mex 58:225-8. 1993
  2. ncbi [Chronic pancreatitis. Main symptoms: chronic abdominal pain, weight loss in steatorrhea, secondary diabetes mellitus]
    G Schulthess
    Medizinische Poliklinik, Universitatsspital Zurich
    Praxis (Bern 1994) 94:1139-45. 2005
  3. ncbi Does pancreatic elastase-1 in stools predict steatorrhea in type 1 diabetes?
    Franco Cavalot
    Diabetes Unit, Department of ClinicalBiological Sciences, University of Turin, San Luigi Gonzaga Hospital, 10043 Orbassano, Turin, Italy
    Diabetes Care 29:719-21. 2006
  4. ncbi An enteric-coated high-buffered pancrelipase reduces steatorrhea in patients with cystic fibrosis: a prospective, randomized study
    Mary Sue Brady
    Indiana University School of Health and Rehabilitation Sciences, Indianapolis, IN 46202 5119, USA
    J Am Diet Assoc 106:1181-6. 2006
  5. ncbi Increased postprandial responses of GLP-1 and GIP in patients with chronic pancreatitis and steatorrhea following pancreatic enzyme substitution
    Filip K Knop
    Dept of Internal medicine F, Gentofte Hospital, Univ of Copenhagen, Niels Andersens Vej 65, DK 2900 Hellerup, Denmark
    Am J Physiol Endocrinol Metab 292:E324-30. 2007
  6. ncbi The effects of oral pancreatic enzymes (Creon 10 capsule) on steatorrhea: a multicenter, placebo-controlled, parallel group trial in subjects with chronic pancreatitis
    Michael Safdi
    Greater Cincinnati Gastroenterology Associates, Cincinnati, OH 45219, USA
    Pancreas 33:156-62. 2006
  7. ncbi Lipoprotein lipase mutation S447X associated with pancreatic calcification and steatorrhea in hyperlipidemic pancreatitis
    Yu Ting Chang
    Department of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan
    J Clin Gastroenterol 43:591-6. 2009
  8. ncbi Cystic fibrosis presenting as diabetes insipidus unresponsive to desmopressin
    S Vande Velde
    Cystic Fibrosis Centre, Ghent University Hospital, Ghent, Belgium
    Acta Gastroenterol Belg 70:300-1. 2007
  9. ncbi Unresponsive or non-compliant steatorrhea in cystic fibrosis?
    Aleksandra Lisowska
    Department of Gastroenterology and Metabolism, Poznan University of Medical Sciences, Szpitalna 27 33, 60 572 Poznan, Poland
    J Cyst Fibros 5:253-5. 2006
  10. ncbi [Pathophysiological significance of steatorrhea as well as of hydroxystearic acids in the feces of calves with diarrhea]
    K Doll
    Klinik für Wiederkäuer und Schweine Innere Medizin und Chirurgie, Justus Liebig Universitat Giessen
    Dtsch Tierarztl Wochenschr 111:22-8. 2004

Detail Information

Publications189 found, 100 shown here

  1. ncbi [Intestinal lymphoid nodular hyperplasia in a patient with acquired dysgammaglobulinemia, chronic diarrhea, and bacterial overgrowth syndrome]
    B Castañeda-Romero
    Departamento de Gastroenterologia, Instituto Nacional de la Nutricion Salvador Zubiran, Mexico, DF
    Rev Gastroenterol Mex 58:225-8. 1993
    ..We described the clinical out come of a young man with diarrhea, steatorrhea and history of upper respiratory tract infections in whom INLH was established by clinical, radiological, ..
  2. ncbi [Chronic pancreatitis. Main symptoms: chronic abdominal pain, weight loss in steatorrhea, secondary diabetes mellitus]
    G Schulthess
    Medizinische Poliklinik, Universitatsspital Zurich
    Praxis (Bern 1994) 94:1139-45. 2005
  3. ncbi Does pancreatic elastase-1 in stools predict steatorrhea in type 1 diabetes?
    Franco Cavalot
    Diabetes Unit, Department of ClinicalBiological Sciences, University of Turin, San Luigi Gonzaga Hospital, 10043 Orbassano, Turin, Italy
    Diabetes Care 29:719-21. 2006
  4. ncbi An enteric-coated high-buffered pancrelipase reduces steatorrhea in patients with cystic fibrosis: a prospective, randomized study
    Mary Sue Brady
    Indiana University School of Health and Rehabilitation Sciences, Indianapolis, IN 46202 5119, USA
    J Am Diet Assoc 106:1181-6. 2006
    Enteric-coated (EC) high-buffered (2.5 mEq [2.5 mmol] bicarbonate per capsule) pancrelipase microsphere enzymes were compared to EC-nonbuffered pancreatic enzymes for efficacy in reducing steatorrhea in patients with cystic fibrosis.
  5. ncbi Increased postprandial responses of GLP-1 and GIP in patients with chronic pancreatitis and steatorrhea following pancreatic enzyme substitution
    Filip K Knop
    Dept of Internal medicine F, Gentofte Hospital, Univ of Copenhagen, Niels Andersens Vej 65, DK 2900 Hellerup, Denmark
    Am J Physiol Endocrinol Metab 292:E324-30. 2007
    ..These results suggest that the secretion of GLP-1 and GIP is under influence of the digestion and absorption of nutrients in the small intestine and that PES increases insulin secretion...
  6. ncbi The effects of oral pancreatic enzymes (Creon 10 capsule) on steatorrhea: a multicenter, placebo-controlled, parallel group trial in subjects with chronic pancreatitis
    Michael Safdi
    Greater Cincinnati Gastroenterology Associates, Cincinnati, OH 45219, USA
    Pancreas 33:156-62. 2006
    ..The primary objective of this study was to compare the effect of Creon 10 with placebo in the control of steatorrhea in chronic pancreatitis patients...
  7. ncbi Lipoprotein lipase mutation S447X associated with pancreatic calcification and steatorrhea in hyperlipidemic pancreatitis
    Yu Ting Chang
    Department of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan
    J Clin Gastroenterol 43:591-6. 2009
    ..The factors that whether and how genes involving lipid metabolism including lipoprotein lipase (LPL) and apolipoprotein CII (apo CII) influence occurrence of acute attack of pancreatitis and chronic pancreatitis is not clear...
  8. ncbi Cystic fibrosis presenting as diabetes insipidus unresponsive to desmopressin
    S Vande Velde
    Cystic Fibrosis Centre, Ghent University Hospital, Ghent, Belgium
    Acta Gastroenterol Belg 70:300-1. 2007
    ..This case report shows how a diagnosis can be delayed when you are mislead by atypical symptoms. It shows the importance of looking in napkins and argues for the inclusion of CF in the differential diagnosis of polyuria in infants...
  9. ncbi Unresponsive or non-compliant steatorrhea in cystic fibrosis?
    Aleksandra Lisowska
    Department of Gastroenterology and Metabolism, Poznan University of Medical Sciences, Szpitalna 27 33, 60 572 Poznan, Poland
    J Cyst Fibros 5:253-5. 2006
    In 105 pancreatic insufficient CF patients (steatorrhea and low fecal elastase-1 concentrations), the effectiveness of pancreatic enzyme therapy (PET) has been assessed (fecal fat losses and coefficient of fat reabsorption)...
  10. ncbi [Pathophysiological significance of steatorrhea as well as of hydroxystearic acids in the feces of calves with diarrhea]
    K Doll
    Klinik für Wiederkäuer und Schweine Innere Medizin und Chirurgie, Justus Liebig Universitat Giessen
    Dtsch Tierarztl Wochenschr 111:22-8. 2004
    ....
  11. ncbi Effect of triglyceride structure on fecal excretion of 13C-labeled triglycerides
    Sally A Schuette
    BioChemAnalysis Corp, 2201 W Campbell Park Drive, Chicago, IL 60612 3501, USA
    J Am Coll Nutr 22:511-8. 2003
    ....
  12. ncbi Chronic high-fat diet affects intestinal fat absorption and postprandial triglyceride levels in the mouse
    Valerie Petit
    Ecole Nationale Supérieure de Biologie Appliquée à la Nutrition et à l Alimentation, 5170 Centre National de la Recherche Scientifique 1214 Institut National de la Recherche Agronomique Université de Bourgogne, Dijon, France
    J Lipid Res 48:278-87. 2007
    ..These data demonstrate that a chronic high-fat diet greatly affects intestinal physiology and body lipid use in the mouse...
  13. ncbi Clinical application of 13C-Hiolein breath test in assessing pancreatic exocrine insufficiency
    Da Yu Sun
    Department of Gastroenterology, Huashan Hospital, Fudan University, Shanghai 200040, China
    Hepatobiliary Pancreat Dis Int 2:449-52. 2003
    ..To examine the feasibility and significance of 13C-Hiolein breath test in evaluating chronic pancreatitis-related exocrine insufficiency and efficacy of enzyme treatment...
  14. ncbi The effect of zinc supplements in cystic fibrosis patients
    S Van Biervliet
    Pediatric Department, UZ Ghent, Ghent, Belgium
    Ann Nutr Metab 52:152-6. 2008
    ..To study the effect of Zn supplements in cystic fibrosis (CF) on disease evolution...
  15. ncbi Quality of life assessment after pancreatic enzyme replacement therapy in chronic pancreatitis
    Laszlo Czako
    First Department of Medicine, Semmelweis University, Budapest
    Can J Gastroenterol 17:597-603. 2003
    ..To evaluate the quality of life (QoL) of patients with chronic pancreatitis before and after pancreatic enzyme replacement therapy in a prospective, multicentre, follow-up study...
  16. ncbi Dysprosium chloride as a nonabsorbable gastrointestinal marker for studies of stable isotope-labeled triglyceride excretion in man
    Sally A Schuette
    BioChemAnalysis Corp, Chicago, IL 60612 3501, USA
    J Am Coll Nutr 22:379-87. 2003
    ....
  17. ncbi Omeprazole, a proton pump inhibitor, improves residual steatorrhoea in cystic fibrosis patients treated with high dose pancreatic enzymes
    Marijke Proesmans
    Department of Paediatrics, University Hospital Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium
    Eur J Pediatr 162:760-3. 2003
    ..5-16.5 g/day) to 5.5 g (quartiles 4.9-8.1 g/day) (P<0.01). The same improvement was noted when fat absorption was calculated: 87% (quartiles 81-89%) without versus 94% (quartiles 90-96%) with omeprazole (P<0.001)...
  18. ncbi Pancreatic enzyme therapy for pancreatic exocrine insufficiency
    J Enrique Domínguez-Muñoz
    Department of Gastroenterology, University Hospital of Santiago de Compostela, C Choupana, S N, E 15706 Santiago de Compostela, Spain
    Curr Gastroenterol Rep 9:116-22. 2007
    Pancreatic exocrine insufficiency with steatorrhea is a major consequence of pancreatic diseases (eg, chronic pancreatitis, cystic fibrosis, severe acute necrotizing pancreatitis, pancreatic cancer), extrapancreatic diseases such as ..
  19. ncbi [Diffuse primary fat replacement of the pancreas: an unusual cause of steatorrhea]
    Alain Aubert
    Service de Gastroenterologie, Hopital Saint Louis, 75010 Paris
    Gastroenterol Clin Biol 31:303-6. 2007
    ..We report two adult patients with chronic diarrhoea and steatorrhea whose morphologic abnormalities revealed diffuse fat replacement of the pancreas...
  20. ncbi Fat malabsorption screening in chronic pancreatitis
    Vincent Dumasy
    Department of Endocrinology, Erasmus Hospital, Free University of Brussels, Belgium
    Am J Gastroenterol 99:1350-4. 2004
    ....
  21. ncbi Long-term clinical outcome after endoscopic pancreatic ductal drainage for patients with painful chronic pancreatitis
    Myriam Delhaye
    Medicosurgical Department of Gastroenterology, Erasme University Hospital, 1070 Brussels, Belgium
    Clin Gastroenterol Hepatol 2:1096-106. 2004
    ..The authors evaluated long-term clinical outcome after endoscopic pancreatic ductal drainage, focusing on pain and pancreatic endocrine/exocrine functions...
  22. ncbi Early decline of pancreatic function in cystic fibrosis patients with class 1 or 2 CFTR mutations
    Jaroslaw Walkowiak
    Institute of Pediatrics, Department of Gastroenterology and Metabolism, Karol Marcinkowski University of Medical Sciences, 60 572 Poznan, Poland
    J Pediatr Gastroenterol Nutr 40:199-201. 2005
    Most cystic fibrosis (CF) patients develop steatorrhea and require pancreatic enzyme replacement therapy...
  23. ncbi Pancreatic exocrine insufficiency in HIV-positive patients
    D A Price
    Department of Infectious Diseases, Newcastle General Hospital, Newcastle upon Tyne, UK
    HIV Med 6:33-6. 2005
    ..We describe the management of a cohort of eight HIV-positive patients on antiretroviral medication with evidence of pancreatic insufficiency consisting of chronic diarrhoea and a low faecal elastase measurement...
  24. ncbi Comparing the urinary pancreolauryl ratio and faecal elastase-1 as indicators of pancreatic insufficiency in clinical practice
    D A Elphick
    Department of Gastroenterology, Barnsley District General Hospital, Barnsley, UK
    Pancreatology 5:196-200. 2005
    ..Both tests have previously been validated against 'gold standard' tests of pancreatic function, but their use in a clinical setting has never been directly compared...
  25. ncbi Faecal elastase-I: helpful in analysing steatorrhoea?
    T Symersky
    Department of Gastroenterology Hepatology C4 P, Leiden University Medical Centre, P O Box 9600, 2300 RC Leiden, The Netherlands
    Neth J Med 62:286-9. 2004
    ..However, little information is available on the specificity of this test in the analysis of steatorrhoea. Our aim was to evaluate the clinical value of FE-1 in the analysis of patients sent in for faecal fat determination...
  26. ncbi Chronic diarrhea
    Peggy D Headstrom
    Department of Gastroenterology, University of Washington, Seattle, Washington, USA
    Clin Gastroenterol Hepatol 3:734-7. 2005
  27. ncbi Faecal pancreatic elastase--1 a non invasive measure of exocrine pancreatic function
    S D Amanquah
    Department of Chemical Pathology, University of Ghana Medical School, Accra, Ghana
    West Afr J Med 23:240-4. 2004
    ..Pancreatic elastase-1, is released into blood circulation during inflammation of the pancreas, but unlike most pancreatic enzymes it is stable during intestinal passage and not degraded...
  28. ncbi Conjugated bile acid replacement therapy in short bowel syndrome patients with a residual colon
    C Kapral
    Department of Medicine, Konventhospital of Barmherzige Brüder, Linz, Austria
    Z Gastroenterol 42:583-9. 2004
    ....
  29. ncbi Does the pancreas really produce much more lipase than required for fat digestion?
    Frederic Carriere
    Laboratory of Enzymology at Interfaces and Physiology of Lipolysis, CNRS UPR 9025 IBSM, Marseille, France
    JOP 6:206-15. 2005
    ..not exist between the amounts of human pancreatic lipase secreted in chronic pancreatitis and the degree of steatorrhea, which was considered to appear only after more than 90% of the pancreatic secretory capacity had been lost...
  30. pmc Phenotypic and genetic characterization of patients with features of "nonclassic" forms of cystic fibrosis
    Joshua D Groman
    Cyctic Fibrosis Foundation Genotyping Center and McKusick Nathans Institute of Genetic Medicine, Bloomberg School of Public Health, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore, MD 21287, USA
    J Pediatr 146:675-80. 2005
    ....
  31. ncbi Congenital short pancreas
    Juan Du
    Department of Gastroenterology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
    Chin Med J (Engl) 120:259-62. 2007
  32. ncbi Surgical treatment for serous cystadenoma of pancreas--segmental pancreatectomy or conventional resection?
    Cheng Hsi Su
    Division of General Surgery, Department of Surgery, Taipei Veterans General Hospital, National Yang Ming University, Taipei, Taiwan
    Hepatogastroenterology 51:595-8. 2004
    ..e. distal pancreatectomy or pancreaticoduodencetomy in patients with serous cystadenoma of the pancreas...
  33. ncbi A proposed model for the assembly of chylomicrons
    M M Hussain
    Department of Biochemistry, School of Medicine, MCP Hahnemann University, Philadelphia, PA 19129, USA
    Atherosclerosis 148:1-15. 2000
    ..CM retention disease, an inherited recessive disorder, is characterized by chronic diarrhea with steatorrhea in infancy, abdominal distention and failure to thrive...
  34. ncbi The deconjugation ability of bacteria isolated from the jejunal fluids in the blind loop syndrome with high 14CO2 excretion--using the breath analysis technique and thin-layer chromatography
    K Shindo
    First Department of Internal Medicine, Yokohama City University School of Medicine, Japan
    Life Sci 45:2275-83. 1989
    ..to levels below the critical micellar concentration by several factors, fat malabsorption and subsequent steatorrhea were induced (1,-4). Furthermore, H. Fromm and A. F...
  35. ncbi Reappraisal of a method of reconstruction after pancreatoduodenectomy
    N J Lygidakis
    Department of Surgical Oncology, Henry Dunant Hospital, Athens, Greece
    Hepatogastroenterology 52:1077-82. 2005
    ..The present study is designed to substantiate the claims of various advantages of this method of PD and reconstruction and to explain the rationale behind this method...
  36. ncbi The thyroid and the gut
    Ellen C Ebert
    Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ, USA
    J Clin Gastroenterol 44:402-6. 2010
    ..Transit time from mouth to cecum is accelerated, resulting in diarrhea. Steatorrhea is due to hyperphagia and stimulation of the adrenergic system...
  37. ncbi Management of gastrointestinal disorders in children with HIV infection
    Alfredo Guarino
    Department of Pediatrics, University Federico II, Naples, Italy
    Paediatr Drugs 6:347-62. 2004
    ..The digestive-absorptive functions are impaired, with steatorrhea, nutrient malabsorption, and increased permeability occurring in 20-70% of children...
  38. ncbi CREON (Pancrelipase Delayed-Release Capsules) for the treatment of exocrine pancreatic insufficiency
    Robert J Kuhn
    Division of Pharmacy, Practice and Science, University of Kentucky, Lexington, Kentucky 40536 0596, USA
    Adv Ther 27:895-916. 2010
    ..The symptoms include maldigestion, malnutrition, weight loss, flatulence, and steatorrhea. Pancreatic enzyme replacement therapy (PERT) is the standard treatment for EPI; it is regulated in many ..
  39. ncbi Tropical sprue in expatriates from the tropics living in the continental United States
    F A Klipstein
    Department of Medicine, University of Rochester School of Medicine and Dentistry, New York
    Medicine (Baltimore) 48:475-91. 1969
    ..dose of folic acid; 27 of 28 tested had malabsorption of vitamin B12; and 23 of 27 persons tested had steatorrhea. Jejunal morphology was abnormal in 34 of 35 subjects biopsied prior to treatment; villi were completely absent ..
  40. ncbi Benign intracranial hypertension in an older child with cystic fibrosis
    V Lucidi
    Department of Gastroenterology, Hospital Bambino Gesu, Rome, Italy
    Pediatr Neurol 9:494-5. 1993
    ..Laboratory investigations indicated pathologic steatorrhea, elevated electrolytes in 3 sweat tests, and low serum levels of vitamins A and E...
  41. ncbi Epidemiology, clinical features and diagnosis of gastroenteropancreatic endocrine tumours
    P Tomassetti
    Department of Internal Medicine and Gastroenterology, University ol Bologna, Italy
    Ann Oncol 12:S95-9. 2001
    ..the 'somatostatinoma syndrome' involves gallbladder dysfunction and gallstones, diarrhoea with or without steatorrhea, and impaired glucose tolerance...
  42. ncbi Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice
    Paul A Dawson
    Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    J Biol Chem 278:33920-7. 2003
    ..acid malabsorption, mutations in the ileal bile acid transporter gene (Slc10a2) lead to congenital diarrhea, steatorrhea, and reduced plasma cholesterol levels...
  43. ncbi [Effectiveness and complications of bariatric surgery in the treatment of morbid obesity]
    J Ocón Bretón
    Servicio de Endocrinologia y Nutricion, Unidad de Nutrición, Hospital Clinico Universitario Lozano Blesa, Zaragoza, Espana
    Nutr Hosp 20:409-14. 2005
    ..The aim of this work has been to analyze the anthropometrical, nutritional, digestive and cardiovascular risk factors changes and quality of life in patients with morbid obesity submitted to bariatric surgery...
  44. ncbi A missense mutation in FIC1 is associated with greenland familial cholestasis
    L W Klomp
    Department of Pediatric Gastroenterology, University Medical Center, Utrecht, The Netherlands
    Hepatology 32:1337-41. 2000
    ..Patients present with jaundice, pruritus, bleeding episodes, and steatorrhea, and die in childhood due to end-stage liver disease...
  45. ncbi Long-term outcome after resection for chronic pancreatitis in 224 patients
    Hartwig Riediger
    Department of Surgery, University of Freiburg, Hugstetter Str 55, 79106, Freiburg, Germany
    J Gastrointest Surg 11:949-59; discussion 959-60. 2007
    ....
  46. ncbi Pancreatin therapy in patients with insulin-treated diabetes mellitus and exocrine pancreatic insufficiency according to low fecal elastase 1 concentrations. Results of a prospective multi-centre trial
    Nils Ewald
    Third Medical Department and Policlinic, Giessen University Hospital, Giessen, Germany
    Diabetes Metab Res Rev 23:386-91. 2007
    ..Patients with fecal elastase 1 concentration (FEC) <100 microg/g have also been demonstrated to suffer from steatorrhea in about 60% of cases, indicating the need of pancreatic enzyme replacement therapy...
  47. ncbi Conjugated bile acid replacement therapy reduces urinary oxalate excretion in short bowel syndrome
    Michael Emmett
    Department of Internal Medicine, Baylor University Medical Center, Dallas, TX 75246, USA
    Am J Kidney Dis 41:230-7. 2003
    Patients with short bowel syndrome (SBS) have steatorrhea, in part because of bile acid malabsorption that causes decreased bile acid secretion into the duodenum and consequent fat maldigestion...
  48. ncbi Hereditary pancreatitis: clinical features and inheritance characteristics of the R122C mutation in the cationic trypsinogen gene (PRSS1) in six Spanish families
    Gonzalo de las Heras-Castaño
    Hepato Gastroenterology Unit, Marqués de Valdecilla Universitary Hospital, Santander, Spain
    JOP 10:249-55. 2009
    ..Hereditary pancreatitis is an autosomal dominant disease which is caused by mutations in the PRSS1 gene...
  49. ncbi Improvement of acromegaly after octreotide LAR treatment
    Ruth Mangupli
    Endocrinology and Metabolism Service, Caracas University Hospital, Caracas, Capital District, Venezuela
    Pituitary 6:29-34. 2003
    ..005). The drug was well tolerated with few adverse effects Diarrhea, flatulence and steatorrhea were observed during the administration of subcutaneous octreotide in 18.2% of patients...
  50. ncbi Pancreaticoduodenectomy with Roux-Y anastomosis in reconstructing the digestive tract: report of 26 patients
    You Gang Ma
    Department of Second Biliary Surgery, Eastern Hepatobiliary Surgery Hospital, Shanghai 200438, China
    Hepatobiliary Pancreat Dis Int 1:611-3. 2002
    ..To explore the way to lower the morbidity and mortality of patients after pancreaticoduodenectomy...
  51. ncbi Brain white-matter lesions in celiac disease: a prospective study of 75 diet-treated patients
    M Kieslich
    Department of Pediatrics, Johann Wolfgang Goethe University, Frankfurt Main, Germany
    Pediatrics 108:E21. 2001
    ..The gastrointestinal manifestation suggests a severe enteropathy of the small intestine with malabsorption, steatorrhea, and weight loss because of a deranged mucosal immune response...
  52. ncbi Chronic pancreatitis in primary hyperparathyroidism: comparison with alcoholic and idiopathic chronic pancreatitis
    Sanjay K Bhadada
    Department of Endocrinology and Metabolism, Post Graduate Institute of Medical Education PGIMER, Chandigarh, India
    J Gastroenterol Hepatol 23:959-64. 2008
    ..There is also no data comparing the clinical profile of chronic pancreatitis secondary to primary hyperparathyroidism with that of alcohol related and idiopathic chronic pancreatitis...
  53. ncbi [Steatorrhea and its treatment with pancreatic enzymes in endocrine tumors of the pancreas (pancreatic adenomas)]
    M J Varas
    Hospital Cruz Roja, L Hospitalet de Llobregat, Barcelona
    Rev Esp Enferm Dig 78:27-30. 1990
    We report the treatment of steatorrhea with pancreatic enzymes in four pancreatic endocrine tumors treated in our hospital. All four patients were males, with a mean age of 50 +/- 4.6, a basal steatorrhea of 10.8 +/- 3...
  54. ncbi Pancreatic enzyme replacement therapy in post-pancreatectomy patients
    M Braga
    Department of Surgery, Scientific Institute H S Raffaele, Milano, Italy
    Int J Pancreatol 5:37-44. 1989
    ..05). At the hospital checkup, the D-xylose test was normal in all patients and steatorrhea had decreased from a mean of 32.8 g/d without enzyme supplementation to 16...
  55. ncbi Findings on endoscopic retrograde cholangiopancreatography and pancreatic function test in suspected chronic pancreatitis and negative cross-sectional imaging
    Mansour A Parsi
    Center for Endoscopy and Pancreatobiliary Disorders, Digestive Disease Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Clin Gastroenterol Hepatol 6:1432-6. 2008
    ....
  56. ncbi Blind loop syndrome after biliopancreatic diversion: a diagnostic challenge
    H Fabry
    Department of Surgery, Academic Surgical Center Stuivenberg, Antwerp, Belgium
    Obes Surg 11:643-5. 2001
    ..Malabsorption of fat and starch is one of the main goals of the BPD. Ingestion of an excess of fat leads to steatorrhea. As a side-effect, malabsorption of iron, calcium and other elements can occur causing anemia and hypocalcemia...
  57. ncbi Non-stented pancreaticogastrostomy for 111 patients undergoing pylorus-preserving pancreaticoduodenectomy
    Yi Ming Shyr
    Department of Surgery, Veterans General Hospital Taipei, National Yang Ming University, Taipei, Taiwan
    Hepatogastroenterology 52:253-7. 2005
    ....
  58. ncbi Rickets and dysmorphic findings in a child with abetalipoproteinemia
    Mohammed Y Hasosah
    Department of Pediatric Gastroenterology, King Abdul Aziz Medical City, National Guard Hospital, PO Box 8202, Jeddah 21482, Kingdom of Saudi Arabia
    Saudi Med J 31:1169-71. 2010
    Abetalipoproteinemia (ABL) is characterized by acanthocytosis, hypocholesterolemia, and steatorrhea. Here, we describe a case of ABL associated with rickets and dysmorphic findings and the subsequent therapeutic course in an 18-month-old ..
  59. ncbi Prolonged enteral feeding is often required to avoid long-term nutritional and metabolic complications after esophagogastric dissociation
    Chrystele Madre
    Assistance Publique Hopitaux de Paris, Universite Paris Diderot, Hopital Robert Debre, Paris, France
    J Pediatr Gastroenterol Nutr 50:280-6. 2010
    ..Although the long-term results in terms of GERD control have been previously reported, those regarding the nutritional and metabolic status have never been documented...
  60. ncbi Phenotypic expression of familial hypobetalipoproteinemia in three kindreds with mutations of apolipoprotein B gene
    P Tarugi
    Dipartimento di Scienze Biomediche, Universita di Modena e Reggio Emilia, Via Campi 287, I 41100 Modena, Italy
    J Lipid Res 42:1552-61. 2001
    ..15 not detectable in plasma. They showed steatorrhea and fatty liver. In N.L...
  61. ncbi Molecular diagnosis of cystic fibrosis in Indian patients--a preliminary report
    T F Ashavaid
    Research Laboratories, PD Hinduja National Hospital and Medical Research Centre, Veer Savarkar Marg, Mahim, Mumbai 400 016, India
    J Assoc Physicians India 51:345-8. 2003
    ....
  62. ncbi [Small intestine bacterial overgrowth]
    E L Leung Ki
    Service de gastro entérologie et d hépatologie, CHUV
    Rev Med Suisse 6:186-8, 190-1. 2010
    ..It typically presents with diarrhea, flatulence and a syndrome of malabsorption (steatorrhea, macrocytic anemia). However, it may be asymptomatic in the eldery...
  63. ncbi [Absorption of medium chain triglycerides in patients with blind loop syndrome]
    R A Pereira Filho
    Departamento de Clinica Medica, Faculdade de Ciências Médicas da Universidade Estadual de Campinas UNICAMP
    Arq Gastroenterol 25:75-81. 1988
    ..Six patients had steatorrhea due to gastrojejunal anastomosis and 4 due to diabetic neuropathy...
  64. ncbi Now that fecal elastase is available in the United States, should clinicians start using it?
    Paul G Lankisch
    Clinic of Internal Medicine, Municipal Clinic of Lueneburg, Boegelstrasse 1, D 21339 Lueneburg, Germany
    Curr Gastroenterol Rep 6:126-31. 2004
    ..exocrine pancreatic insufficiency or chronic pancreatitis and differentiating pancreatic from nonpancreatic steatorrhea or diarrhea--cannot be solved by pancreatic elastase-1 determination...
  65. ncbi Pancreatoduodenal surgery in patients with multiple endocrine neoplasia type 1: Operative outcomes, long-term function, and quality of life
    Y Nancy You
    Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Surgery 142:829-36; discussion 836.e1. 2007
    ..Potential oncologic benefits of PD resection must be weighed against operative morbidities, compromised pancreatic function, and quality of life (QOL)...
  66. ncbi [D-lactic acidosis in an 11-year-old patient with short bowel syndrome]
    P Soler Palacin
    Unidad de Enfermedades Infecciosas Pediátricas, Hospital Vall d Hebron, Barcelona, Spain
    An Pediatr (Barc) 64:385-7. 2006
    ..Symptoms include nutrient and electrolyte malabsorption, steatorrhea and diarrhea, which can result in failure to thrive...
  67. ncbi [Improvement of intestinal function in cystic fibrosis patients using probiotics]
    D Infante Pina
    Unidad de Gastroenterologia, Hepatología y Soporte Nutricional, Hospital Materno Infantil Vall d Hebron, Universidad Autonoma de Barcelona, Barcelona, Espana
    An Pediatr (Barc) 69:501-5. 2008
    ..The aim of our study is to determine the prevalence of bacterial overgrowth in cystic fibrosis patients and try to improve the intestinal function with the administration of probiotics...
  68. ncbi Alipase versus nonenteric-coated enzymes in pancreatic insufficiency. A french multicenter crossover comparative study
    H Gouerou
    Hopital du Morvan, Centre Hospitalier Regional, Brest, France
    Int J Pancreatol 5:45-50. 1989
    ..Pancreatic insufficiency was diagnosed in patients with signs of chronic pancreatitis who showed steatorrhea (fecal fat excretion greater than 8.0 g/24 h). The dosage of P was 9 capsules/d and that of E, 3 vials/d...
  69. ncbi EUR-1008 pancreatic enzyme replacement is safe and effective in patients with cystic fibrosis and pancreatic insufficiency
    Jamie L Wooldridge
    Cincinnati Children s Hospital Medical Center, Division of Pulmonary Medicine, ML 2021, 3333 Burnet Ave, Cincinnati, OH 45229, USA
    J Cyst Fibros 8:405-17. 2009
    ..Unlike currently marketed PEPs, EUR-1008 contains the label-claimed lipase content. Safety and efficacy were assessed in younger (<7 years) and older (> or =7 years) CF patients with EPI...
  70. pmc Loss of enteroendocrine cells in mice alters lipid absorption and glucose homeostasis and impairs postnatal survival
    Georg Mellitzer
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, INSERM U964, CNRS UMR 7104, Universite de Strasbourg, Illkirch, France
    J Clin Invest 120:1708-21. 2010
    ..Mutant mice were growth retarded and had yellowish stool suggestive of steatorrhea. Subsequent analyses revealed that Ngn3Deltaint mice had impaired lipid absorption, reduced weight gain, and ..
  71. ncbi Which method should we select for pancreatic anastomosis after pancreaticoduodenectomy?
    Ji Hun Kim
    Department of Surgery, Ajou University School of Medicine, San 5, Wonchondong, Yeongtonggu, Suwon, 442 749, Korea
    World J Surg 33:326-32. 2009
    ..This study was designed to compare surgical, morphological, and functional outcomes of pancreaticoduodenectomy (PD) according to the types of pancreaticoenterostomy performed and to suggest a proper anastomotic method after PD...
  72. ncbi [Functional outcome and quality of life after pancreaticoduodenectomy]
    S Le Page
    Service de Chirurgie Digestive, Hopital de la Croix Rousse, Lyon
    J Chir (Paris) 145:32-6. 2008
    ..The goal of this retrospective unicentric pilot study was to assess the the functional outcome after pancreaticoduodenectomy and its effect on the patient's quality of life...
  73. ncbi Tropical calcific pancreatitis
    G Choudhuri
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
    Ceylon Med J 53:4-6. 2008
  74. ncbi An unusual case of osteomalacia as the presenting feature of coeliac disease
    Taoufik Harzy
    El Ayachi Hospital, Rabat Salé University Medical School, Sale, Morocco
    Rheumatol Int 26:90-1. 2005
  75. ncbi Spontaneous exocrine pancreas hypoplasia in specific pathogen-free C3HeB/FeJ and 101/H mouse pups causes steatorrhea and runting
    Michael T Cheeseman
    Pathology Group, Mary Lyon Centre, Medical Research Council Harwell, Didcot, Oxfordshire, UK
    Comp Med 57:210-6. 2007
    ..3% to 1.8% of litters born in our inbred 101/H and C3HeB/FeJ mouse colonies had pups with steatorrhea and runting. Clinically affected male and female pups were first identified when they were from 14 to 25 d old...
  76. ncbi Metformin in the treatment of patients with non-alcoholic steatohepatitis
    A Uygun
    Department of Gastroenterology, Gulhane Military Medical Academy, Ankara, Turkey
    Aliment Pharmacol Ther 19:537-44. 2004
    ..Increased insulin resistance is the major pathogenic mechanism in the development of non-alcoholic steatohepatitis...
  77. ncbi [Clinical spectrum of celiac disease]
    S Daum
    Medizinische Klinik I, Gastroenterologie, Rheumatologie und Infektiologie, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin
    Dtsch Med Wochenschr 129:S79-81. 2004
  78. ncbi Clinical quiz
    Hassan Abolghasemi
    Department of Pediatrics, Baghiatallah General Hospital, Baghiatallah University of Medical Sciences, Tehran, Iran
    J Pediatr Gastroenterol Nutr 40:229, 243. 2005
  79. ncbi [Non-alcoholic liver steatorrhea secondary to clozapine]
    Caroline Bell
    Can J Psychiatry 49:575-6. 2004
  80. ncbi Severe osteomalacia in a patient with idiopathic chronic pancreatitis
    N Kurtulmus
    Division of Endocrinology, Metabolism and Nutrition, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Capa, Turkey
    Scott Med J 50:172-3. 2005
    ..She had a history from childhood of steatorrhea and abdominal pain after a fatty meal and became vegetarian at age five years...
  81. ncbi Surgical treatment of chronic pancreatitis in young patients
    Feng Zhou
    Pancreatic Disease Institute, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China
    J Huazhong Univ Sci Technolog Med Sci 34:701-5. 2014
    ..therapeutic ERCP intervention to surgical intervention, 2 patients developed diabetes, 5 patients developed steatorrhea, and 5 patients developed pancreatic type B pain...
  82. pmc Diagnosis and treatment of pancreatic exocrine insufficiency
    Bjorn Lindkvist
    Björn Lindkvist, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, SE 413 45 Gothenburg, Sweden
    World J Gastroenterol 19:7258-66. 2013
    ..Failure in any of these steps may result in pancreatic exocrine insufficiency, which leads to steatorrhea, weight loss and malnutrition-related complications, such as osteoporosis...
  83. ncbi EUS-assisted rendezvous stenting of the pancreatic duct for chronic calcifying pancreatitis with multiple pseudocysts
    Adrian Saftoiu
    Department of Gastroenterology, University of Medicine and Pharmacy, Craiova, Romania
    Pancreatology 7:74-9. 2007
    ..However, recent studies currently recommend the use of both techniques in complex cases...
  84. pmc Application of a novel tool for diagnosing bile acid diarrhoea
    James A Covington
    School of Engineering, University of Warwick, Coventry, UK
    Sensors (Basel) 13:11899-912. 2013
    ..We believe that this work may lead to a new tool to diagnose BAD, which is cheaper, quicker and easier that current methods. ..
  85. pmc Digestive manifestations of parathyroid disorders
    Bassam Abboud
    Bassam Abboud, Ronald Daher, Department of General Surgery, Hotel Dieu de France Hospital, Faculty of Medicine, Saint Joseph University, Beirut 166830, Lebanon
    World J Gastroenterol 17:4063-6. 2011
    ..The main manifestation of hypoparathyroidism is steatorrhea due to a deficit in exocrine pancreas secretion...
  86. ncbi [Autoimmune pancreatitis associated with rheumatoid arthritis: successful combination therapy with steroids and methotrexate]
    M Mustak
    Abteilung für Rheumatologie und Osteologie, Kaiser Franz Josef Spital Wien
    Dtsch Med Wochenschr 136:1842-4. 2011
    MEDICAL HISTORY AND CLINICAL FINDINGS: A 70-year-old female patient suffered from steatorrhea and upper abdominal discomfort for 8 weeks combined with new onset of arthralgia in both hands...
  87. ncbi Serum zinc concentrations in cystic fibrosis patients aged above 4 years: a cross-sectional evaluation
    S Van Biervliet
    Paediatric Department, Ghent University Hospital, UZ Ghent, De Pintelaan 185, Ghent 9000, Belgium
    Biol Trace Elem Res 119:19-26. 2007
    ..Assess the risk of zinc (Zn) deficiency in the older cystic fibrosis (CF) population...
  88. ncbi [Diagnostics and therapy of chronic pancreatitis]
    A Konig
    Klinik fur Gastroenterologie, Endokrinologie und Stoffwechsel, Universitätsklinikum Giessen und Marburg GmbH, Standort Marburg, Baldingerstrasse, 35043, Marburg, Germany
    Internist (Berl) 49:695-707; quiz 708-9. 2008
    ..Common symptoms of CP comprise abdominal pain radiating to the back, diarrhea, steatorrhea and the development of diabetes...
  89. ncbi Intraductal papillary mucinous neoplasm (IPMN) and chronic pancreatitis: overlapping pathological entities? Two case reports
    Athanasios Petrou
    Department of Hepatobilary Surgery, Churchill Hospital, Oxford, United Kingdom
    JOP 12:50-4. 2011
    ..often misdiagnosed as chronic pancreatitis because of symptoms of relapsing abdominal pain, pancreatitis, and steatorrhea and imaging findings of a dilated pancreatic duct of cystic lesions that are frequently confused with ..
  90. ncbi Somatostatinoma: collision with neurofibroma and ultrastructural features
    W Varikatt
    Department of Anatomical Pathology, South Western Area Pathology Service, Sydney, Australia
    Histol Histopathol 21:1171-80. 2006
    ..Neither tumour was associated with the somatostatinoma syndrome comprising associated diabetes mellitis, steatorrhoea and cholelithiasis...
  91. ncbi Usefulness of a 13C-labeled mixed triglyceride breath test for assessing pancreatic exocrine function after pancreatic surgery
    Hiroyuki Nakamura
    Department of Surgery, Division of Clinical Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Surgery 145:168-75. 2009
    ..We evaluated the usefulness of a (13)C-labeled mixed triglyceride breath test for assessing pancreatic exocrine function after pancreatic surgery...
  92. ncbi Effectiveness and tolerability of colesevelam hydrochloride for bile-acid malabsorption in patients with cancer: a retrospective chart review and patient questionnaire
    Linda Wedlake
    Department of Nutrition and Dietetics, The Royal Marsden Hospital, London, United Kingdom
    Clin Ther 31:2549-58. 2009
    ..Commercially available bile-acid sequestrants are not well tolerated by >80% of patients...
  93. ncbi [Fat absorption after total gastrectomy in rats submitted to Roux-en-Y or Rosanov-like double-transit technique]
    Gustavo Sevá-Pereira
    Postgraduate Program in Surgery, FCM, UNICAMP, Sao Paulo, Brazil
    Acta Cir Bras 21:380-4. 2006
    b>Steatorrhea is one of the most common complications in reconstruction after total gastrectomy...
  94. ncbi Sweat test in asthmatic children; a single center study
    Bahram Mirsaeid Ghazi
    Department of Pediatrics, Bahrami Children Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Iran J Allergy Asthma Immunol 5:139-42. 2006
    ..signs and symptoms among these 35 patients were: Cough (35/35), Dyspnea (7/35), Chronic Diarrhea (6/35), and steatorrhea (1/35). Failure to thrive was found in 31 of 35 patients...
  95. ncbi Non-stented pancreaticogastrostomy after pylorus-preserving pancreaticoduodenectomy
    Yi Ming Shyr
    Department of Surgery, Taipei Veterans General Hospital, Taiwan, ROC
    Zhonghua Yi Xue Za Zhi (Taipei) 65:254-9. 2002
    ..Surgical risk of non-stented pancreaticogastrostomy was also assessed to clarify the importance of stenting in pancreatic anastomosis...
  96. ncbi The commercially available ELISA for pancreatic elastase 1 based on polyclonal antibodies does measure an as yet unknown antigen different from purified elastase 1. Binding studies and clinical use in patients with exocrine pancreatic insufficiency
    P D Hardt
    Third Medical Department and Policlinic, Giessen University Hospital, Giessen, Germany
    Z Gastroenterol 41:903-6. 2003
    ..assays but higher levels in ELISA 2, resulting in false normal results even in some patients with pancreatic steatorrhea. Since the reference range used in both assays has been established using ELISA 1, ELISA 2 must be re-evaluated ..
  97. ncbi Surgical management of chronic pancreatitis and the role of islet cell autotransplantation
    Thomas S Helling
    Department of Surgery, University of Missouri Kansas City School of Medicine, Kansas City, Missouri 64111, USA
    Curr Surg 60:463-9. 2003
    Chronic pancreatitis is a disease characterized by disabling pain, inability to eat, steatorrhea, and eventual malnutrition. This often results in repeated hospitalizations and attempts to control symptoms with various analgesic regimens...
  98. pmc Utilization of sialic acid as a coreceptor is required for reovirus-induced biliary disease
    Erik S Barton
    Department of Microbiology and Immunology and Lamb Center for Pediatric Research, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    J Clin Invest 111:1823-33. 2003
    ..Strikingly, mice infected with T3SA+ but not T3SA- developed steatorrhea and bilirubinemia...
  99. ncbi Chronic pancreatitis in the elderly in Japan
    Terumi Kamisawa
    Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan
    Pancreatology 4:223-7; discussion 227-8. 2004
    ..In this study, we analyzed the clinical features of elderly Japanese patients with chronic pancreatitis and compared them with those of late-onset chronic pancreatitis patients in Western countries...
  100. ncbi Association between steatorrhea, growth, and immunologic status in children with perinatally acquired HIV infection
    T A Sentongo
    Division of Gastroenterology, Hepatology, and Nutrition, Children s Memorial Medical Center, 2300 Children s Plaza No 65, Chicago, IL 60614
    Arch Pediatr Adolesc Med 155:149-53. 2001
    To examine the prevalence of steatorrhea and exocrine pancreatic insufficiency (EPI) and their association with growth and immune status variables in children with perinatally acquired human immunodeficiency virus (HIV) infection.
  101. ncbi Persistence of the intestinal defect in abetalipoproteinaemia after liver transplantation
    C P Braegger
    Division of Gastroenterology and Nutrition, University Children s Hospital, Zurich, Switzerland
    Eur J Pediatr 157:576-8. 1998
    ..After this procedure her serum lipoprotein profile was corrected; however, fat malabsorption and steatorrhea persisted because the primary defect, a mutant microsomal triglyceride-transfer protein, remains expressed in ..

Research Grants16

  1. PANCREATIC LIPASES AND COLIPASE IN LIPOLYSIS AND OBESITY
    Mark Lowe; Fiscal Year: 2007
    ..Because procolipase deficient newborns have steatorrhea independent of colipase-dependent pancreatic lipase (PTL), we will analyze neonatal pancreas and breast milk ..
  2. Molecular Control of Brown Adipose Cell Fate and Energy Metabolism
    Shingo Kajimura; Fiscal Year: 2013
    ..However, due to side effects including depression, oily bowel movements and steatorrhea, there is an urgent need for alternative approaches...
  3. GROWTH AND NUTRITION IN ALAGILLE SYNDROME
    ANDREW MULBERG; Fiscal Year: 1999
    ..Most of these children have steatorrhea which could be a major contributory factor to secondary growth failure and failure to thrive...
  4. MPT INHIBITOR IND 50,820 IN FAMILIAL HYPERCHOLESTEROLEM*
    Marina Cuchel; Fiscal Year: 2009
    ..All subjects tolerated the drug up to the maximal dose with little to no steatorrhea. Three of the six subjects had substantial increases in liver transaminases, but levels rapidly decreased ..
  5. Mechanism and Therapies for HAART Induced Diarrhea
    Tibor Sipos; Fiscal Year: 2001
    ..for the use of a bicarbonate-buffered and enteric-coated pancrelipase for the treatment of diarrhea and steatorrhea in HIV positive patients is to demonstrate that the HAART drugs interfere with any one of the key digestive ..
  6. PROTEIN DRUG DELIVERY BASED ON STABILIZED PROTEIN
    ALEXEY MARGOLIN; Fiscal Year: 2000
    ..II, we will prepare a drug product prototype for the use in the treatment of pancreatic insufficiency, and steatorrhea in cystic fibrosis patients...
  7. NOVEL PROTEASE FORMULATION BASED ON CROSSLINKED CRYSTALS
    Bhami Shenoy; Fiscal Year: 2004
    ..and along with TheraCLEC-Lipase for use in the treatment of pancreatic insufficiency, azotorrhea and steatorrhea in cystic fibrosis and chronic pancreatitis patients...
  8. Accurate Noninvasive Test of Steatorrhea in Infants
    Morteza Janghorbani; Fiscal Year: 2004
    ..The long-term objectives of this proposed project are to develop a "Test Kit" for quantitative assessment of steatorrhea in infants without the need for control of dietary fat intake and quantitative collections of stools for ..
  9. SENSITIVE TEST OF GENERALIZED STEATORRHEA
    Morteza Janghorbani; Fiscal Year: 1999
    The current "gold-standard" for quantitative assessment of steatorrhea, 72-h stool fat, is universally recommended in evaluation of malabsorption but vastly under-utilized because it is tedious and difficult to perform...
  10. A HLA Mouse Model for Gluten Sensitivity and Enteropathy
    Joseph Murray; Fiscal Year: 2009
    ..abstract_text> ..
  11. Epidemiology of Celiac Disease: A Population Based Study
    Joseph A Murray; Fiscal Year: 2010
    ..This will provide crucial data that will determine the need for early detection by screening and treatment of silent celiac disease, which may affect 1% of Americans. ..
  12. DIETARY OBESITY
    George Bray; Fiscal Year: 2007
    ..We now propose these well founded, important and exciting studies which will provide critical new insights into anatomical, physiological and molecular mechanisms by which high levels of dietary fat induce obesity. ..
  13. BIOLOGY OF HUMAN INTRAEPITHELIAL LYMPHOCYTES
    Ellen Ebert; Fiscal Year: 2002
    ..These studies will determine the mechanism of IEL chemotaxis toward secreted products of ECs, why IL-15 is more potent than IL-2 in inducing LAK activity by IELs, and how IL-10 and IL-12 augment this activity. ..
  14. Patient Oriented Research in Pediatric Nutrition
    Nancy Krebs; Fiscal Year: 2008
    ..abstract_text> ..
  15. Host-Microbial Control of Deoxycholate Producton
    Paul Dawson; Fiscal Year: 2005
    ..Aim 3: To cross the Slcl0a2 null allele into additional mouse strains as a first step toward cloning the genes responsible controlling deoxycholate production (colonization by the bai operon bacteria). ..