testicular diseases

Summary

Summary: Pathological processes of the TESTIS.

Top Publications

  1. ncbi Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects
    N E Skakkebaek
    Department of Growth and Reproduction, Copenhagen University Hospital, Copenhagen, Denmark
    Hum Reprod 16:972-8. 2001
  2. ncbi Androgen action in the masculinization programming window and development of male reproductive organs
    D J Macleod
    MRC Human Reproductive Sciences Unit, Centre for Reproductive Biology, University of Edinburgh, The Queen s Medical Research Institute, Edinburgh, UK
    Int J Androl 33:279-87. 2010
  3. ncbi Testicular microlithiasis: what does it mean clinically?
    Haitham Dagash
    Department of Paediatric Urology, Sheffield Children s Hospital, Sheffield, UK
    BJU Int 99:157-60. 2007
  4. ncbi Testicular microlithiasis: what is its association with testicular cancer?
    A M Bach
    Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    Radiology 220:70-5. 2001
  5. ncbi Human 'testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate
    Jane S Fisher
    MRC Human Reproductive Sciences Unit, Centre for Reproductive Biology, The Chancellor s Building, University of Edinburgh, 49 Little France Crescent, Edinburgh EH16 4SB, UK
    Hum Reprod 18:1383-94. 2003
  6. ncbi Histological evaluation of the human testis--approaches to optimizing the clinical value of the assessment: mini review
    R I McLachlan
    Prince Henry s Institute, Monash University, Clayton, Victoria, Australia
    Hum Reprod 22:2-16. 2007
  7. ncbi Right varicocele and hypoxia, crucial factors in male infertility: fluid mechanics analysis of the impaired testicular drainage system
    Yigal Gat
    Andrology Unit, Maynei HaYeshua Hospital and Department of Obstetrics and Gynecology, Rabin Medical Center, Beilinson Campus, Petah Tiqva and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Reprod Biomed Online 13:510-5. 2006
  8. ncbi Upregulated NADPH oxidase contributes to diabetic testicular complication and is relieved by strontium fructose 1,6-diphosphate
    M Xu
    Research Division of Pharmacology, China Pharmaceutical University, Nanjing, China
    Exp Clin Endocrinol Diabetes 118:459-65. 2010
  9. ncbi Isolated testicular vasculitis presenting as a tumor-like lesion
    Fadi N Joudi
    Department of Urology, University of Iowa, Iowa City, USA
    J Urol 171:799. 2004
  10. ncbi Testicular polyarteritis nodosa mimicking testicular neoplasm
    Gokhan Atis
    Goztepe Training and Research Hospital, 2nd Urology Clinic, Istanbul
    ScientificWorldJournal 10:1915-8. 2010

Research Grants

Detail Information

Publications189 found, 100 shown here

  1. ncbi Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects
    N E Skakkebaek
    Department of Growth and Reproduction, Copenhagen University Hospital, Copenhagen, Denmark
    Hum Reprod 16:972-8. 2001
    ..Otherwise, important biological information may be lost...
  2. ncbi Androgen action in the masculinization programming window and development of male reproductive organs
    D J Macleod
    MRC Human Reproductive Sciences Unit, Centre for Reproductive Biology, University of Edinburgh, The Queen s Medical Research Institute, Edinburgh, UK
    Int J Androl 33:279-87. 2010
    ..controls. In conclusion, we show that the size of all male reproductive organs is programmed by androgen exposure in the MPW, but that growth towards this size is dependent on androgen action postnatally...
  3. ncbi Testicular microlithiasis: what does it mean clinically?
    Haitham Dagash
    Department of Paediatric Urology, Sheffield Children s Hospital, Sheffield, UK
    BJU Int 99:157-60. 2007
    ....
  4. ncbi Testicular microlithiasis: what is its association with testicular cancer?
    A M Bach
    Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    Radiology 220:70-5. 2001
    ..To determine the prevalence of testicular microlithiasis in patients who were referred for scrotal ultrasonography (US) at a tertiary care cancer center and to evaluate the association between microlithiasis and cancer...
  5. ncbi Human 'testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate
    Jane S Fisher
    MRC Human Reproductive Sciences Unit, Centre for Reproductive Biology, The Chancellor s Building, University of Edinburgh, 49 Little France Crescent, Edinburgh EH16 4SB, UK
    Hum Reprod 18:1383-94. 2003
    ..The disorders comprising human 'testicular dysgenesis syndrome' (TDS) may be increasing in incidence. TDS originates in fetal life but the mechanisms are not known, and discerning them requires an animal model...
  6. ncbi Histological evaluation of the human testis--approaches to optimizing the clinical value of the assessment: mini review
    R I McLachlan
    Prince Henry s Institute, Monash University, Clayton, Victoria, Australia
    Hum Reprod 22:2-16. 2007
    ..We propose a new diagnosis code for testicular biopsies that addresses the needs of ART clinicians and allows data storage and retrieval of value in clinical practice and research...
  7. ncbi Right varicocele and hypoxia, crucial factors in male infertility: fluid mechanics analysis of the impaired testicular drainage system
    Yigal Gat
    Andrology Unit, Maynei HaYeshua Hospital and Department of Obstetrics and Gynecology, Rabin Medical Center, Beilinson Campus, Petah Tiqva and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Reprod Biomed Online 13:510-5. 2006
    ....
  8. ncbi Upregulated NADPH oxidase contributes to diabetic testicular complication and is relieved by strontium fructose 1,6-diphosphate
    M Xu
    Research Division of Pharmacology, China Pharmaceutical University, Nanjing, China
    Exp Clin Endocrinol Diabetes 118:459-65. 2010
    ..It is due to its extra-energy supply and an antioxidant activity of FDP-Sr...
  9. ncbi Isolated testicular vasculitis presenting as a tumor-like lesion
    Fadi N Joudi
    Department of Urology, University of Iowa, Iowa City, USA
    J Urol 171:799. 2004
  10. ncbi Testicular polyarteritis nodosa mimicking testicular neoplasm
    Gokhan Atis
    Goztepe Training and Research Hospital, 2nd Urology Clinic, Istanbul
    ScientificWorldJournal 10:1915-8. 2010
    ..We described the case of a 57-year-old patient with isolated testicular PAN who presented with a testicular mass mimicking a primary testicular tumor...
  11. ncbi Prevalence of testicular microlithiasis in an asymptomatic population
    Selim Serter
    Departments of Radiology, School of Medicine, Celal Bayar University, Manisa, Turkey
    Scand J Urol Nephrol 40:212-4. 2006
    ..The aim of this prospective study was to determine the true prevalence of testicular microlithiasis in an asymptomatic population by means of ultrasound screening...
  12. ncbi Testicular vasculitis mimicking a testicular neoplasm
    B B McGuire
    Ir Med J 99:27-8. 2006
    ..We report the general clinical presentation, methods of investigation and subsequent management. This is the first time it has been described in the elderly population...
  13. ncbi Testicular microlithiasis: is it a benign condition with malignant potential?
    U Otite
    Department of Urology, The Barts and Royal London NHS Trust and Queen Mary and Westfield College, University of London, UK
    Eur Urol 40:538-42. 2001
    ....
  14. ncbi Does testicular microlithiasis matter? A review
    F N A C Miller
    Department of Radiology, King s College Hospital, Denmark Hill, London SE5 9RS, UK
    Clin Radiol 57:883-90. 2002
    ..Similarly, there is limited evidence to support the association with infertility. Not surprisingly, algorithms for the follow-up of patients with TM on ultrasound have been difficult to formulate...
  15. ncbi Testicular microlithiasis: histologic and immunohistochemical findings in 11 pediatric cases
    Ricardo Drut
    Department of Pathology, Hospital de Ninos, Superiora Sor Maria Ludovica, 1900 La Plata, Buenos Aires, Argentina
    Pediatr Dev Pathol 5:544-50. 2002
    ..It is unclear how this may be related to the development of germ cell tumors. However, the presence of calcospherites in gonadoblastoma may indicate a combined Sertoli cell and germ cell derangement in the genesis of TM...
  16. ncbi Repeated testicular infarction in a patient with sickle cell disease: a possible mechanism for testicular failure
    Maomi Li
    Department of Pathology, Montefiore Medical Center Albert Einstein College of Medicine, Bronx, New York 10467, USA
    Urology 62:551. 2003
    ..We propose repeated testicular infarction as a probable mechanism of testicular failure and impaired fertility in patients with sickle cell disease...
  17. ncbi Testicular microlithiasis: an unreported feature of McCune-Albright syndrome in males
    Malgorzata Wasniewska
    Department of Pediatrics, Universities of Messina, Pisa, and Milan, Reginal Margherita Hospital of Turin, Italy
    J Pediatr 145:670-2. 2004
    ..To ascertain the incidence of testicular microlithiasis (TM) in boys with McCune-Albright syndrome (MAS)...
  18. ncbi Significance of testicular microlithiasis
    Stefan Zastrow
    Department of Urology, University Hospital Carl Gustav Carus, Technical University of Dresden, Dresden, Germany
    Urol Int 75:3-7. 2005
    ..Testicular microlithiasis is an uncommon condition characterized by calcifications within the seminiferous tubules. The true prevalence in a normal population has not been defined...
  19. ncbi Testicular microlithiasis: a review and its association with testicular cancer
    Hani H Rashid
    Department of Urology, Strong Memorial Hospital, University of Rochester Medical Center, Rochester, NY 14652, USA
    Urol Oncol 22:285-9. 2004
    ..Therefore, follow-up at this time should be dictated based on risk factors for developing testis cancer more than on the presence of TM...
  20. ncbi Testicular microlithiasis: our experience of 10 years
    Diana L Lam
    University of California, Davis Medical Center, Sacramento, CA, USA
    J Ultrasound Med 26:867-73. 2007
    ..The correlation between TM and testicular malignancies is variable. The purpose of this study was to review our 10-year experience regarding the prevalence of TM and its association with testicular malignancies...
  21. ncbi Microsurgical denervation of the spermatic cord for chronic orchialgia: long-term results from a single center
    Kurt H Strom
    Department of Urology, Rush University Medical Center, Chicago, Illinois, USA
    J Urol 180:949-53. 2008
    ..We assessed the long-term efficacy, complications and patient perceptions of microsurgical denervation of the spermatic cord in the treatment of chronic orchialgia...
  22. pmc Increased prevalence of testicular microlithiasis in men with familial testicular cancer and their relatives
    L A Korde
    Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
    Br J Cancer 99:1748-53. 2008
    ..If proven, this could be clinically important to men in FTGCT families, and may be useful in identifying specific genes involved in FTGCT...
  23. ncbi Microsurgical denervation of the spermatic cord as primary surgical treatment of chronic orchialgia
    L A Levine
    Department of Urology, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, USA
    J Urol 165:1927-9. 2001
    ..CONCLUSIONS: When conservative treatment fails, microsurgical denervation of the spermatic cord should be considered first rate surgical therapy for patients with chronic orchialgia...
  24. ncbi Management of chronic testalgia by microsurgical testicular denervation
    Axel Heidenreich
    Klinik für Urologie and Kinderurologie, Philipps Universitat Marburg, Baldingerstrasse, 35043 Marburg, Germany
    Eur Urol 41:392-7. 2002
    ..Success rates of conservative and surgical measures including epididymectomy and orchiectomy rarely exceed 55-73% and 10-40%, respectively. We report our experience on microsurgical testicular denervation as therapeutic option in CTP...
  25. ncbi Amifostine protects against early but not late toxic effects of doxorubicin in infant rats
    K Jahnukainen
    Pediatric Endocrinology Unit, Karolinska Institute, Karolinska Hospital, 171 76 Stockholm, Sweden
    Cancer Res 61:6423-7. 2001
    ....
  26. ncbi The prevalence of testicular microlithiasis in an asymptomatic population of men 18 to 35 years old
    A C Peterson
    Department of Surgery, Madigan Army Medical Center, Tacoma, Washington 98431, USA
    J Urol 166:2061-4. 2001
    ..This study indicates that testicular microlithiasis is a common finding in asymptomatic men that may not be related to testicular cancer...
  27. ncbi Ipsilateral orchialgia after laparoscopic donor nephrectomy
    Fernando J Kim
    James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Endourol 17:405-9. 2003
    ..In an effort to assess the incidence of this problem, determine the etiology, and adapt preventive measures, we reviewed our experience...
  28. ncbi Increased risk of carcinoma in situ in patients with testicular germ cell cancer with ultrasonic microlithiasis in the contralateral testicle
    Mette Holm
    University Department of Growth and Reproduction, Copenhagen University Hospital, Denmark
    J Urol 170:1163-7. 2003
    ..We compared clinical and histological data regarding the contralateral testicle in a population of men diagnosed with testicular germ cell cancer to find features associated with an increased risk of bilateral neoplasia...
  29. ncbi Management of simple intratesticular cysts: a single-institution 11-year experience
    Iqbal S Shergill
    Princess Alexandra Hospital, Harlow, Essex, United Kingdom
    Urology 67:1266-8. 2006
    ..To evaluate the clinicoradiologic findings and outcomes of management of simple intratesticular cysts, by review of an 11-year experience...
  30. ncbi From the archives of the AFIP: tumors and tumorlike lesions of the testis: radiologic-pathologic correlation
    Paula J Woodward
    Department of Radiologic Pathology, Armed Forces Institute of Pathology, 6825 16th St, NW, Bldg 54, Rm M 121, Washington, DC 20306 6000, USA
    Radiographics 22:189-216. 2002
    ..Other benign lesions that can be suspected on the basis of imaging findings and history include intratesticular cysts, epidermoid cysts, congenital adrenal hyperplasia, and sarcoidosis...
  31. ncbi Expression of transcription factor GATA-4 during human testicular development and disease
    I Ketola
    Children s Hospital, University of Helsinki, Finland
    J Clin Endocrinol Metab 85:3925-31. 2000
    ..GATA-4 protein is abundantly present in Sertoli and Leydig cell tumors, suggesting a relationship to tumorigenesis or tumor progression in somatic cell-derived testicular neoplasms...
  32. ncbi The origins and time of appearance of focal testicular dysgenesis in an animal model of testicular dysgenesis syndrome: evidence for delayed testis development?
    Gary R Hutchison
    MRC Human Reproductive Sciences Unit, Centre for Reproductive Biology, Queen s Medical Research Institute, Edinburgh, UK
    Int J Androl 31:103-11. 2008
    ..5 after DBP exposure, which may be indicative of a wider delay in testis cell development and organisation, and this might account for some of the unexplained findings...
  33. ncbi Bilateral testicular microlithiasis predicts the presence of the precursor of testicular germ cell tumors in subfertile men
    C A De Gouveia Brazao
    Department of Andrology, and Laboratory for Experimental Pathology, Josephine Nefkens Institute, Erasmus Medical Center University Medical Center Rotterdam, The Netherlands
    J Urol 171:158-60. 2004
    ..We determined the predictive value of unilateral and bilateral testicular microlithiasis for CIS in subfertile men, a known risk population for TGCTs (approximately 1%)...
  34. ncbi Complex multilocular cystic lesion of rete testis, accompanied by smooth muscle hyperplasia, mimicking intratesticular Leydig cell neoplasm
    Eduard Fridman
    Department of Pathology, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Hashomer, Israel
    Virchows Arch 447:768-71. 2005
    ..To the best of our knowledge, no similar complex lesion of the rete testis has yet been reported...
  35. ncbi Giant cell arteritis mimicking a testicular tumour
    S Sundaram
    Department of Rheumatology, Morriston Hospital, Swansea, UK
    Rheumatol Int 20:215-6. 2001
    ..Giant cell arteritis involving the bladder, prostate, uterus, and adnexa have been described before. To our knowledge, this is the first described case of giant cell arteritis affecting the testis...
  36. ncbi Testicular hematocele mimicking a testicular tumor: a case report and review of literature
    A Shamsa
    Mashhad University of Medical Sciences, Department of Urology, Anesthesiology and Kidney Transplant, MUMS, Mashhad, Iran
    Transplant Proc 34:2141-2. 2002
  37. ncbi Relapse of brucellosis simulating testis tumor
    Izzet Kocak
    Department of Urology, Adnan Menderes University Faculty of Medicine, Aydin 09110, Turkey
    Int J Urol 11:683-5. 2004
    ..Even in the absence of systemic symptoms, the possible relapse of brucellosis as an abscess formation in the testis should be considered as a rare cause of testicular mass in patients who live in endemic regions...
  38. ncbi Testicular microlithiasis and its relation to testicular cancer on ultrasound findings of symptomatic men
    Erika Ringdahl
    Department of Family and Community Medicine, University of Missouri Hospitals and Clinics, Columbia, Missouri, USA
    J Urol 172:1904-6. 2004
    ..We reviewed testicular microlithiasis (TM) on scrotal ultrasound in relation to the incidence of testicular neoplasm in males 17 to 45 years old with scrotal symptoms...
  39. ncbi Primary testicular amyloidosis mimicking tumor in a cryptorchid testis
    Roberto Casella
    Scott Department of Urology, Baylor College of Medicine, Houston, Texas, USA
    Urology 59:445. 2002
    ..After radical orchiectomy, the histologic evaluation revealed primary amyloidosis of the testis. The pathogenesis and clinical presentation of testicular amyloidosis are reviewed...
  40. ncbi Testicular epidermoid cyst: a case report and review of the clinicopathologic features
    Joshua D Wiesenthal
    Department of Pathology, The University of Western Ontario, London, Ontario, Canada
    Can J Urol 11:2133-5. 2004
    ..Radical orchidectomy was performed revealing the pathologic diagnosis. The presentation, evaluation and management of epidermoid cysts are discussed...
  41. ncbi Isolated testicular polyarteritis nodosa mimicking testicular neoplasm-long-term follow-up
    Zohar A Dotan
    Department of Urology, Sheba Medical Center, Tel Hashomer, Israel
    Urology 62:352. 2003
    ..The postoperative laboratory evaluation was negative. Long-term follow-up, without systemic treatment, showed no evidence of recurrence in the remainder of the testis or development of systemic vasculitis...
  42. ncbi Testicular microlithiasis and carcinoma in situ overview and proposed clinical guideline
    N J van Casteren
    Department of Urology, Erasmus MC, Rotterdam, The Netherlands
    Int J Androl 32:279-87. 2009
    ..A long-term active follow-up schedule, including ultrasonography and physical examinations, is not indicated in the remaining patients with TM...
  43. ncbi How worrisome is testicular microlithiasis?
    Raymond A Costabile
    Urology Department, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    Curr Opin Urol 17:419-23. 2007
    ..Until 2001 little prospective data were available on the prevalence or natural history of testicular microlithiasis in the healthy male population...
  44. ncbi Avian infectious bronchitis virus: a possible cause of reduced fertility in the rooster
    David A Boltz
    Department of Animal Sciences, University of Illinois at Urbana Champaign, 1207 West Gregory, Urbana, IL 61801, USA
    Avian Dis 48:909-15. 2004
    ..17 x 10(7) sperm/g of testis. We conclude that the use of a live attenuated AIBV vaccine increases the incidence of epididymal stones in roosters, resulting in decreased sperm production and decreased serum testosterone concentrations...
  45. ncbi Testicular hypotrophy does not correlate with grade of adolescent varicocele
    Joseph P Alukal
    Department of Urology, Children s Hospital Boston, Hunnewell 3, 300 Longwood Avenue, Boston, MA 02115, USA
    J Urol 174:2367-70, discussion 2370. 2005
    ..As this relationship has significant clinical implications, we studied the correlation between grade and testicular volume disproportion in our adolescent varicocele population...
  46. ncbi Localized traumatic infarction of the testicle
    John McCabe
    Department of Urology, Countess of Chester Hospital, Chester, UK
    Scand J Urol Nephrol 38:442-3. 2004
    ..Ultrasonically it is extremely difficult to accurately distinguish testicular infarct from neoplasm. We describe a case which highlights this, together with the previously unreported phenomenon of a localized infarct secondary to trauma...
  47. ncbi [Physiopathology of the infertile testicle. Etiopathogenesis of varicocele]
    Manuel Nistal
    Departamento de Anatomia Patologica, Hospital Universitario La Paz, Madrid, Espana
    Arch Esp Urol 57:883-904. 2004
    ..To systematically review pathologic testicular lesions in patients with varicocele. To establish factors that may have prognostic significance on post-treatment fertility...
  48. ncbi Ethnic differences in occurrence of TDS-- genetics and/or environment?
    Aleksander Giwercman
    Fertility Centre and Department of Urology, Scanian Andrology Centre, Malmo University Hospital, Lund University, Malmo, Sweden
    Int J Androl 29:291-7; discussion 304-6. 2006
    ..Such 'susceptibility genes' need to be identified, those involved in the synthesis, action and metabolism of sex steroids being strong candidates...
  49. ncbi [Andrological relevance of testicular biopsies]
    Frank Michael Köhn
    Klinik und Poliklinik fur Dermatologie und Allergologie, Technische Universitat Munchen
    J Dtsch Dermatol Ges 3:532-57; quiz 557-8. 2005
  50. ncbi [Diagnostic image (234). A man with an acute scrotum]
    J G H van Roermund
    Canisius Wilhelmina Ziekenhuis, afd Urologie, 6500 GS Nijmegen
    Ned Tijdschr Geneeskd 149:758. 2005
    ..A 48-year-old man presented with acute testicular pain caused by a haematoma in a non seminoma testicular tumour...
  51. ncbi The painful scrotum: an ultrasonographical approach to diagnosis
    M Muttarak
    Department of Radiology, Chiang Mai University, 110 Intavaroros Road, Chiang Mai 50200, Thailand
    Singapore Med J 46:352-7; quiz 358. 2005
    ..This pictorial essay is intended to review the causes, US appearances of disease processes causing the painful scrotum, and examination pitfalls of scrotal US...
  52. ncbi Testicular dysgenesis syndrome: possible role of endocrine disrupters
    Katrine Bay
    University Department of Growth and Reproduction, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Best Pract Res Clin Endocrinol Metab 20:77-90. 2006
    ..Clinicians should be aware of the interconnection between the different features of TDS, and inclusion of a programme for early detection of testis cancer in the management of infertile men with poor semen quality is recommended...
  53. ncbi Metachronous testicular tumors developing 5 and 9 years after the diagnosis of testicular microlithiasis
    Simon Gilbert
    Department of Urology, Darent Valley Hospital, Dartford, England
    J Ultrasound Med 26:981-4. 2007
  54. ncbi Intratesticular haematoma: differentiation from tumour on clinical history and ultrasound appearances in two cases
    H Purushothaman
    Department of Radiology, King s College Hospital, Denmark Hill, London SE9 9RS, UK
    Br J Radiol 80:e184-7. 2007
    ..A clinical history coupled with Doppler ultrasound features is crucial for conservative management...
  55. ncbi Polyorchidism: presentation of 2 cases, review of the literature and a new management strategy
    Mehdi Khedis
    Department of Urology and Andrology, Rangueil Hospital, Toulouse, France
    Urol Int 80:98-101. 2008
    ..To present 2 cases with polyorchidism, to review the literature about polyorchidism, and to propose a rational therapeutic algorithm...
  56. ncbi The testis: the unusual, the rare and the bizarre
    V R Stewart
    Department of Radiology, King s College Hospital, London, UK
    Clin Radiol 62:289-302. 2007
    ....
  57. ncbi [Diagnostic image (305). A boy with a painful and swollen scrotum]
    A van Beurden
    Groene Hart Ziekenhuis, afd Chirurgie, Gouda
    Ned Tijdschr Geneeskd 150:2870. 2006
    ..Left double testis was diagnosed in a 12-year-old boy with a painful and swollen scrotum...
  58. ncbi Epididymal stone formation and decreased sperm production in roosters vaccinated with a killed strain of avian infectious bronchitis virus
    David A Boltz
    Department of Animal Sciences, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Avian Dis 50:594-8. 2006
    ..Histologically, immune cells were seen in the interstitium of efferent ductules containing stones. We conclude that use of a killed vaccine does not reduce the incidence of epididymal stones...
  59. ncbi [CT diagnosis and pathological findings of testicular lesion]
    Gang Duan
    Diagnostic Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
    Nan Fang Yi Ke Da Xue Xue Bao 27:98-100. 2007
    ..To investigate the value of CT scan in the diagnosis and differential diagnosis of testicular space-occupying lesions...
  60. ncbi Epididymo-testicular malacoplakia--a case report
    V Kusuma
    Department of Pathology, Kempegowda Institute of Medical Sciences, Bangalore
    Indian J Pathol Microbiol 49:413-5. 2006
    ..Diagnosis of the same is important as the treatment differs from the other granulomatous lesions in this area. We present a case of malacoplakia involving both the epididymis and testis with a brief review of literature...
  61. ncbi Unilateral benign testicular macro-orchidism in a child: decisions and dilemmas
    C Gerry Henderson
    Division of Urology, Children s National Medical Center, Washington, DC 20010, USA
    Clin Pediatr (Phila) 45:765-7. 2006
  62. ncbi [Increased risk of testicular dysgenesis?]
    Elin L Aschim
    Avdeling for helsefag, Høgskolen i Oslo, Postboks 4 St Olavs plass, 0130 Oslo
    Tidsskr Nor Laegeforen 126:2278-81. 2006
    ..The potential importance of environmental factors must be taken seriously, and the authorities must take action to strengthen the research in this area...
  63. ncbi Testicular schistosomiasis simulating malignancy
    M M Dauda
    Department of Surgery, Ahmadu Bello University Teaching Hospital, Zarira, Nigeria
    Trop Doct 36:182-3. 2006
  64. ncbi [Pathogenesis of neoplastic changes in germ cells as a developmental aspect]
    Jolanta Słowikowska-Hilczer
    Zakład Endokrynologii Płodności, Katedra Andrologii i Endokrynologii Płodności UM w Łodzi
    Pediatr Endocrinol Diabetes Metab 13:37-42. 2007
    ..CIS cells can disappear but with the advancing puberty they may give rise to GCT under the influence of gonadotropins and androgens...
  65. ncbi [Benign space-occupying cysts in the testis. An overview]
    G Bonkat
    Urologische Klinik, Universitatsspital Basel, Spitalstrasse 21, Basel, Switzerland
    Urologe A 46:1697-703. 2007
    ..On diagnosis of a benign lesion of the testis an organ-conserving surgical therapy or an observational watch-and-wait strategy can be recommended in most cases...
  66. ncbi Management of nonpalpable incidental testicular masses
    Timothy M Powell
    Division of Urology, Department of Surgery, Southern Illinois University School of Medicine, Springfield, IL 62794, USA
    J Urol 176:96-8; discussion 99. 2006
    ..We report on 4 patients who presented with nonpalpable testicular masses discovered on scrotal ultrasound, and offer treatment recommendations based on our experience and a review of the literature...
  67. ncbi [Ultrasound of the scrotum]
    G Stuckmann
    Institut fur Radiologie, Kantonsspital Winterthur
    Praxis (Bern 1994) 95:709-20. 2006
    ..In cases of acute scrotum or of vascular and inflammatory lesions, Doppler ultrasound is mandatory. This article gives a systematical survey of the most frequent scrotal lesions and their appearance in ultrasound...
  68. ncbi Testicular and paratesticular pathology in infants and children: the histopathological experience of a tertiary paediatric unit over a 17 year period
    F L Murphy
    Department of Paediatric Urology, Great Ormond Street Children s Hospital, Great Ormond Street, London WC1N 3JH, UK
    Pediatr Surg Int 23:867-72. 2007
    ..Neoplasms represented >20% of the pathology, but the largest clinical group of pathological specimens in this patient population is associated with clinically impalpable or the palpably abnormal testis...
  69. ncbi [Testicular microlithiasis--are biopsy and follow-up necessary?]
    Lisbeth Schjerling
    Hillerød Sygehus, organkirurgisk afdeling A
    Ugeskr Laeger 164:2041-5. 2002
    ..TM is described in otherwise healthy men, but is also found related to cancer and CIS. Here we will discuss the evaluation and follow up of patients with diagnosed TM...
  70. ncbi [Large cell calcifying Sertoli cell tumor of the testis: report of one case]
    Alfonso Latiff Conde
    Fundacion Santa Fe de Bogota, Colombia
    Arch Esp Urol 57:78-82. 2004
    ..To report one case of Sertoli cell testicular tumor of the large cell calcifying type, a rare presentation, and to perform a medical literature review on the topic...
  71. ncbi [Torsion of the spermatic cord and testicular annexes]
    P Mongiat-Artus
    Service d Urologie, Universite Paris VII, Hopital Saint Louis, 1, avenue Claude Vellefaux, 75475 Paris Cedex 10, France
    Ann Urol (Paris) 38:25-34. 2004
    ..But the most important improvement should come from parental and teenagers educational information so that they urgently visit a practitioner in case of acute scrotal pain...
  72. ncbi Benign cystic lesion of the tunica albuginea: a case report
    Kazushi Tanaka
    Division of Urology, Department of Organs Therapeutics, Faculty of Medicine, Kobe University Graduate School of Medicine
    Hinyokika Kiyo 50:45-8. 2004
    ..Although orchiectomy was performed in this case, early consideration and confirmation of benign lesions may permit testicular preservation...
  73. ncbi Cysts of the tunica albuginea
    S J Chou
    Division of Urology, Department of Surgery, Armed Forces Taoyuan General Hospital, Taoyuan, Taiwan, ROC
    Arch Androl 50:89-92. 2004
    ..The authors report 3 cases of cysts of the tunica albuginea. Scrotal ultrasonography facilitates preoperative diagnosis and helps to avoid orchiectomy or to prevent unnecessary surgery...
  74. ncbi [Obstructive azoospermia in men who wish to father children; diagnosis and surgical sperm retrieval]
    D K van der Schoot
    afd Urologie, Universitair Medisch Centrum St Radboud, Postbus 9101, 6500 HB Nijmegen
    Ned Tijdschr Geneeskd 147:2583-7. 2003
    ..To evaluate diagnostic procedures and surgical sperm retrieval in men with suspected obstructive azoospermia who wish to father children...
  75. ncbi Impaired spermatogenesis in men with congenital absence of the vas deferens
    M V Meng
    Department of Urology, University of California San Francisco School of Medicine, California 94143-0738, USA
    Hum Reprod 16:529-33. 2001
    ..In addition, genetic counselling should be offered and testing for genetic lesions, including cystic fibrosis gene mutations and/or variants, Y chromosome microdeletions, and karyotype abnormalities, should be considered...
  76. ncbi [Scrotal ultrasonography. Part I: common non-cancerous pathologies]
    C Roy
    Service de Radiologie B, Chir A, Hopitaux Universitaires de Strasbourg, Hopital Civil, 1 Place de l Hopital, BP 426, 67091 Strasbourg
    J Radiol 84:581-95. 2003
    ..When a tumoral process is suspected, surgery is required to confirm the diagnosis and provide histology. The role of MR remains under evaluation...
  77. ncbi [Current status of high-resolution scrotal echography]
    Rafael Rodríguez-Patrón Rodríguez
    Unidad de Ecografia Urológica, Hospital Ramon y Cajal, Madrid, Espana
    Arch Esp Urol 56:509-20. 2003
    ..To review the main images that can be observed by ultrasound, trying to highlight what decision to take after their finding: exploratory surgery, orchyectomy, or follow-up...
  78. ncbi [The childless couple in the doctor's office. Examination of the male]
    G Haidl
    Klinik und Poliklinik für Haut und Geschlechtskrankheiten, Rheinische Friedrich Wilhelms Universitat Bonn
    MMW Fortschr Med 145:35-6. 2003
  79. ncbi Molecular evidence supporting the neoplastic nature of some epidermoid cysts of the testis
    Cheryl Younger
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis 46202, USA
    Arch Pathol Lab Med 127:858-60. 2003
    ..Loss of heterozygosity of 17p13 has also been demonstrated in germ cell tumors. The incidence of LOH in epidermoid cysts, a possible special form of teratoma, has not been previously determined...
  80. ncbi Re: The prevalence of testicular microlithiasis in an asymptomatic population of men 18 to 35 years old
    A Freeman
    J Urol 169:1474. 2003
  81. ncbi Testicular-sparing surgery: a reasonable option in selected patients with testicular lesions
    M Passarella
    Department of Urology, Tulane University School of Medicine, New Orleans, LA, USA
    BJU Int 91:337-40. 2003
    ..To describe our experience of inguinal exploration in patients who had a reasonable chance of having a benign testicular lesion...
  82. ncbi Epididymal lithiasis in roosters and efferent ductule and testicular damage
    G A B Mahecha
    Departmento de Morfologia, Universidade Federal de Minas Gerais, Belo Horizonte MG, 30190 003, Brazil
    Reproduction 124:821-34. 2002
    ..The severity of the lesion points to potentially severe economical impact in the poultry industry...
  83. ncbi Scrotal ultrasound
    Raymond H Oyen
    Department of Radiology, University Hospitals, Katholieke Universiteit Leuven, Herestraat 49, 3000 Leuven, Belgium
    Eur Radiol 12:19-34. 2002
  84. ncbi Epidermoid cysts of the testes in Taiwanese men
    E Meng
    National Defense Medical Center, National Defense College, Taipei, Taiwan, ROC
    Arch Androl 50:201-5. 2004
    ..The absence of relapse in these patients further supports the use of organ sparing surgery in these young men...
  85. ncbi [Testicular microlithiasis and testicular carcinoma: bilateral calcifications go with increased CIS risk]
    Renate Leinmüller
    Aktuelle Urol 35:367-9. 2004
  86. ncbi [Testicular epidermoid cyst: report of a new case and bibliographic review]
    Víctor Manuel Martínez Silva
    Servicio de Urologia, Hospital Universitario 12 de Octubre, Madrid, Espana
    Arch Esp Urol 57:641-3. 2004
    ..Pathology reveals a cavity consisting of squamous epithelial cells containing keratin and non-nucleated keratic flakes in the absence of atypia or elements of teratoma...
  87. ncbi Testicular ultrasound
    Michael Blaivas
    Section of Emergency Ultrasound, Department of Emergency Medicine, Medical College of Georgia, 1120 15th Street, AF 2039, Augusta, GA 30912 4007, USA
    Emerg Med Clin North Am 22:723-48, ix. 2004
    ....
  88. ncbi [Testicular microlithiasis and cancer of the testis]
    Denis Rey
    Service d Urologie, Hopital Robert Debre, avenue du general Koening, 51032 Reims
    Prog Urol 12:500-3. 2002
    ..On the basis of this case and a review of the literature, the authors discuss the aetiopathogenesis and management of these microscopic stones in a context of cancer...
  89. ncbi Germinal tumor invasion and the role of the testicular stroma
    Alejandro Díez-Torre
    Department of Cell Biology and Histology, School of Medicine and Dentistry, University of the Basque Country, E 48940 Leioa, Vizcaya, Spain
    Int J Dev Biol 48:545-57. 2004
    ..Finally, we discuss prospects for future research on the role of the stroma in the progression and differentiation of male germ cell tumors...
  90. ncbi Analysis of the intratesticular control of spermatogenesis by ex-vivo approaching
    Marie Hélene Perrard
    Institut de Génomique Fonctionnelle de Lyon, Universite de Lyon, Université Lyon I, CNRS INRA Ecole Normale Supérieure de Lyon, Lyon, France
    Folia Histochem Cytobiol 47:S89-94. 2009
    ..There is now evidence that chemical exposure is at least partly responsible for these testicular diseases. If a large number of environmental pollutants are able to affect male fertility and to exert carcinogenic ..
  91. ncbi Blood plasma concentrations of oestradiol-17beta, testosterone and testosterone/oestradiol ratio in dogs with neoplastic and degenerative testicular diseases
    R Mischke
    Clinic for Small Animals, School of Veterinary Medicine, Hannover, Germany
    Res Vet Sci 73:267-72. 2002
    ....
  92. pmc Bilateral male breast cancer with male potential hypogonadism
    Yukiko Hirose
    Department of Oncological and Regenerative Surgery, Institute of Health Biosciences, The University of Tokushima, 3 18 15, Kuramoto Cho, Tokushima 770 8509, Japan
    World J Surg Oncol 5:60. 2007
    ..Risk factors are said to be genetic factors and hormonal abnormalities due to obesity or testicular diseases.
  93. ncbi Testicular adrenal rest tumors and Leydig and Sertoli cell function in boys with classical congenital adrenal hyperplasia
    A Martinez-Aguayo
    Endocrinology Unit, Department of Pediatrics, Pontificia Universidad Catolica de Chile, 833 0074, Santiago, Chile
    J Clin Endocrinol Metab 92:4583-9. 2007
    ..Infertility observed in adult males with congenital adrenal hyperplasia (CAH) has been associated with testicular adrenal rest tumors (TART) that may originate during childhood...
  94. ncbi Scrotal disorders: evaluation of testicular enhancement patterns at dynamic contrast-enhanced subtraction MR imaging
    Y Watanabe
    Depts of Radiology, and Urology, Kurashiki Central Hospital, 1 1 1 Miwa, Kurashiki, 710 8602, Japan
    Radiology 217:219-27. 2000
    ..To evaluate testicular enhancement patterns in various scrotal disorders at dynamic contrast medium-enhanced subtraction magnetic resonance (MR) imaging...
  95. ncbi The impact of commonly prescribed drugs on male fertility
    Tetsuo Hayashi
    Department of Urology, Saitama Medical Center, Saitama Medical University, Kawagoe, Saitama, Japan
    Hum Fertil (Camb) 11:191-6. 2008
    ..Of these 201 men, a total of 165 had no history of testicular diseases nor abnormalities in any examinations...
  96. ncbi Kinetic fluorescence RT-PCR is highly sensitive for detection of germ-cell-tumor-specific transcripts in peripheral blood
    M Schrader
    Department of Urology, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, D 12200 Berlin, Germany
    Int J Mol Med 16:143-7. 2005
    ..controls comprised of samples taken from patients 3 months after treatment, from patients with inflammatory testicular diseases or non-germ-cell-tumors and from healthy males (n=66)...
  97. ncbi Factors influencing testicular volume in young men: results of a community-based survey
    J H Ku
    Departments of Urology, Military Manpower Administration, Seoul, and Soonchunhyang University School of Medicine, Pucheon and Chonan, Korea
    BJU Int 90:446-50. 2002
    ..To investigate the factors influencing testicular volume in young men in the community...
  98. ncbi Deregulation of EZH2 expression in human spermatogenic disorders and testicular germ cell tumors
    Stefan Hinz
    Department of Urology, Universitatsmedizin Berlin, Charite, Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany
    World J Urol 28:631-5. 2010
    ..deregulation of EZH2 expression may contribute to the development and progression of benign and malignant testicular diseases. The objective of this study was to investigate the expression profile of EZH2 in testicular germ cell ..
  99. ncbi [MRI for the diagnosis of Leydig cell testicular tumors]
    Elena Angulo Hervías
    Servicio de Radiodiagnostico, Hospital Universitario Miguel Servet, Zaragoza, Espana
    Arch Esp Urol 60:75-7. 2007
    ..To determine the diagnostic usefulness of MRI in the diagnosis of Leydig cell testicular tumor...
  100. ncbi Estrogen therapy in a male patient with chronic hepatitis C and irradiation-induced testicular dysfunction
    I Shimizu
    Second Department of Internal Medicine, Tokushima University School of Medicine
    Intern Med 40:100-4. 2001
    ..This observation suggests that endogenous estradiol may play a beneficial role in male patients with chronic hepatitis C...
  101. ncbi Spontaneous and age-related testicular findings in beagle dogs
    Michael J Goedken
    Pfizer, Inc, Groton, Connecticut, USA
    Toxicol Pathol 36:465-71. 2008
    ..If evaluation of spermatogenesis is critical, the incidental findings can be minimized by using males over twelve months of age...

Research Grants12

  1. SERTOLI CELL TOXICITY IN VIVO--MICROTUBULE DISRUPTION
    Kim Boekelheide; Fiscal Year: 2001
    ..Together, these complimentary approaches will critically examine key steps in the pathogenetic sequence by which microtubule disrupters alter the supportive capacity of Sertoli cells resulting in loss of germ cells and infertility. ..
  2. ANTI-VIRAL TREATMENT OF DEVELOPING BOVINE EMBRYOS
    Maurice Givens; Fiscal Year: 2002
    ....
  3. ENVIRONMENTAL/INDUSTRIAL TOXICANTS AND TESTICULAR INJURY
    Kim Boekelheide; Fiscal Year: 2003
    ..Together, these complimentary approaches will elucidate the key molecular mechanisms responsible for irreversible testicular injury. ..
  4. Testicular Torsion: Mechanisms and Treatment
    Terry Turner; Fiscal Year: 2005
    ..It is likely that these investigations will be relevant to other forms of oxidative stress inducing testicular dysfunction. ..
  5. PHTHALATE-INDUCED MURINE TESTICULAR DYSGENESIS AND P53
    Kim Boekelheide; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  6. AUTOSOMAL MECHANISMS OF TESTIS INDUCTION
    VICKI MEYERS WALLEN; Fiscal Year: 2005
    ..At the end of this grant period, we will have identified the gene causing this disorder and the step in the testis pathway that is altered by the mutation in timing, quantity, or location of gene expression. ..
  7. Constitutively active LH receptors in transgenic mice
    Prema Narayan; Fiscal Year: 2007
    ..These studies will contribute new information on testicular and ovarian physiology and pathophysiology and provide insight into the molecular mechanisms of FMPP, female infertility and premature ovarian failure. [unreadable] [unreadable]..
  8. Insulin and Oocyte Chromatin Segregation
    Gary Smith; Fiscal Year: 2009
    ..abstract_text> ..
  9. 2006 Environmental Endocrine Disruptors Gordon Conference
    Rex Hess; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  10. Genetic epidemiology of glutathione and CF lung disease
    EDWARD MCKONE; Fiscal Year: 2005
    ..abstract_text> ..
  11. PROTEIN PHOSPHATASES AND OOCYTE MEIOSIS
    Gary Smith; Fiscal Year: 2002
    ..These studies will provide novel information concerning control of oocyte maturation and spindle formation that may subsequently influence the developmental competency of resulting embryos. ..
  12. Sertoli Cell Mediated Engulfment of Apoptotic Germ Cells
    Kodi S Ravichandran; Fiscal Year: 2010
    ..abstract_text> ..