papio

Summary

Summary: A genus of the subfamily CERCOPITHECINAE, family CERCOPITHECIDAE, consisting of five named species: PAPIO URSINUS (chacma baboon), PAPIO CYNOCEPHALUS (yellow baboon), PAPIO PAPIO (western baboon), PAPIO ANUBIS (or olive baboon), and PAPIO HAMADRYAS (hamadryas baboon). Members of the Papio genus inhabit open woodland, savannahs, grassland, and rocky hill country. Some authors consider MANDRILLUS a subgenus of Papio.

Top Publications

  1. ncbi Numerity of a socially housed hamadryas baboon (Papio hamadryas) and a socially housed squirrel monkey (Saimiri sciureus)
    Brian R Smith
    Program in Animal Behavior, Bucknell University, Lewisburg, Pennsylvania 17837, USA
    J Comp Psychol 117:217-25. 2003
  2. ncbi Treponema infection associated with genital ulceration in wild baboons
    S Knauf
    Justus Liebig University, Clinic for Obstetrics, Gynecology and Andrology of Large and Small Animals, Frankfurterstrasse 106, 35393 Giessen, Germany
    Vet Pathol 49:292-303. 2012
  3. ncbi Comparison of the EBNA1 proteins of Epstein-Barr virus and herpesvirus papio in sequence and function
    J L Yates
    Department of Human Genetics, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Virology 222:1-13. 1996
  4. ncbi Introgressive hybridization in southern African baboons shapes patterns of mtDNA variation
    C Keller
    Cognitive Ethology, German Primate Center, 37077 Gottingen, Germany
    Am J Phys Anthropol 142:125-36. 2010
  5. ncbi alpha1,3-Galactosyltransferase gene-knockout pig heart transplantation in baboons with survival approaching 6 months
    Yau Lin Tseng
    Transplantation Biology Research Center, Massachusetts General Hospital Harvard Medical School, Boston, MA, USA
    Transplantation 80:1493-500. 2005
  6. ncbi Genetic structure in a dynamic baboon hybrid zone corroborates behavioural observations in a hybrid population
    M J E Charpentier
    CEFE CNRS, UMR 5175, Montpellier, France
    Mol Ecol 21:715-31. 2012
  7. ncbi T-cell responses during pig-to-primate xenotransplantation
    Eduardo Davila
    Department of Pediatrics, Louisiana State University Health Science Center, Stanley S Scott Cancer Center, New Orleans, LA, USA
    Xenotransplantation 13:31-40. 2006
  8. ncbi A serological survey of Ebola virus infection in central African nonhuman primates
    E M Leroy
    Centre International de Recherches Medicales de Franceville, Institut de Recherche pour le Developpement, UR034, Franceville, Gabon
    J Infect Dis 190:1895-9. 2004
  9. ncbi An analysis of features of pathogenesis in two animal models of Ebola virus infection
    E I Ryabchikova
    State Research Center of Virology and Biotechnology Vector, Research Institute of Molecular Biology, Koltsovo, Russia
    J Infect Dis 179:S199-202. 1999
  10. pmc Mitochondrial phylogeography of baboons (Papio spp.): indication for introgressive hybridization?
    Dietmar Zinner
    Cognitive Ethology, Deutsches Primatenzentrum, Gottingen, Germany
    BMC Evol Biol 9:83. 2009

Detail Information

Publications271 found, 100 shown here

  1. ncbi Numerity of a socially housed hamadryas baboon (Papio hamadryas) and a socially housed squirrel monkey (Saimiri sciureus)
    Brian R Smith
    Program in Animal Behavior, Bucknell University, Lewisburg, Pennsylvania 17837, USA
    J Comp Psychol 117:217-25. 2003
    ..To extend a study conducted by E. M. Brannon and H. S. Terrace (1998, 2000), the authors trained 1 hamadryas baboon (Papio hamadryas) and 1 squirrel monkey (Saimiri sciureus) to respond to stimuli representing the numerosities 1-4 in ..
  2. ncbi Treponema infection associated with genital ulceration in wild baboons
    S Knauf
    Justus Liebig University, Clinic for Obstetrics, Gynecology and Andrology of Large and Small Animals, Frankfurterstrasse 106, 35393 Giessen, Germany
    Vet Pathol 49:292-303. 2012
    ..The disease causes moderate to severe genital ulcerations in a population of olive baboons (Papio hamadryas anubis) at Lake Manyara National Park in Tanzania...
  3. ncbi Comparison of the EBNA1 proteins of Epstein-Barr virus and herpesvirus papio in sequence and function
    J L Yates
    Department of Human Genetics, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Virology 222:1-13. 1996
    ..We have isolated, sequenced, and functionally characterized the EBNA1 gene of herpesvirus papio (HVP), an EBV-like virus that infects baboons...
  4. ncbi Introgressive hybridization in southern African baboons shapes patterns of mtDNA variation
    C Keller
    Cognitive Ethology, German Primate Center, 37077 Gottingen, Germany
    Am J Phys Anthropol 142:125-36. 2010
    ....
  5. ncbi alpha1,3-Galactosyltransferase gene-knockout pig heart transplantation in baboons with survival approaching 6 months
    Yau Lin Tseng
    Transplantation Biology Research Center, Massachusetts General Hospital Harvard Medical School, Boston, MA, USA
    Transplantation 80:1493-500. 2005
    ..The recent generation of alpha1,3-galactosyltransferase gene-knockout (GalT-KO) pigs has allowed investigation of the survival of GalT-KO pig organs in nonhuman primates...
  6. ncbi Genetic structure in a dynamic baboon hybrid zone corroborates behavioural observations in a hybrid population
    M J E Charpentier
    CEFE CNRS, UMR 5175, Montpellier, France
    Mol Ecol 21:715-31. 2012
    ..Specifically, it suggests that anubis baboons are in the process of gradual range expansion into the range of yellow baboons, a pattern potentially explained by behavioural and life history advantages that correlate with anubis ancestry...
  7. ncbi T-cell responses during pig-to-primate xenotransplantation
    Eduardo Davila
    Department of Pediatrics, Louisiana State University Health Science Center, Stanley S Scott Cancer Center, New Orleans, LA, USA
    Xenotransplantation 13:31-40. 2006
    ..To determine the potential role of T lymphocytes in Xenograft (Xg) rejection, we transplanted transgenic hCD46 porcine hearts heterotopically into baboon recipients...
  8. ncbi A serological survey of Ebola virus infection in central African nonhuman primates
    E M Leroy
    Centre International de Recherches Medicales de Franceville, Institut de Recherche pour le Developpement, UR034, Franceville, Gabon
    J Infect Dis 190:1895-9. 2004
    ..They also suggest that future Ebola outbreaks may occur anywhere in the central African forest region...
  9. ncbi An analysis of features of pathogenesis in two animal models of Ebola virus infection
    E I Ryabchikova
    State Research Center of Virology and Biotechnology Vector, Research Institute of Molecular Biology, Koltsovo, Russia
    J Infect Dis 179:S199-202. 1999
    ..The results show that species-specific features of monkeys must be taken into account when choosing an experimental model for studying Ebola virus infection...
  10. pmc Mitochondrial phylogeography of baboons (Papio spp.): indication for introgressive hybridization?
    Dietmar Zinner
    Cognitive Ethology, Deutsches Primatenzentrum, Gottingen, Germany
    BMC Evol Biol 9:83. 2009
    Baboons of the genus Papio are distributed over wide ranges of Africa and even colonized parts of the Arabian Peninsula...
  11. pmc Pancreatic islet amyloidosis, beta-cell apoptosis, and alpha-cell proliferation are determinants of islet remodeling in type-2 diabetic baboons
    Rodolfo Guardado-Mendoza
    Department of Medicine Diabetes Division, University of Texas Health Science Center, San Antonio, TX 78229, USA
    Proc Natl Acad Sci U S A 106:13992-7. 2009
    ..519, P < 0.0001), and different FPG levels were sensitive and specific to predict IA severity. Finally, a predictive model for islet amyloid severity was generated with age and FPG as required variables...
  12. ncbi Arterial wall-determined risk factors to vascular diseases: a nonhuman primate model
    Xing Li Wang
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX, USA
    Cell Biochem Biophys 40:371-88. 2004
    ..The use of baboons from large pedigreed families in these studies will enable the identification of genes that interact with these environmental factors in determining individual risk of atherosclerosis...
  13. pmc Molecular pathways mediating differential responses to lipopolysaccharide between human and baboon arterial endothelial cells
    Qiang Shi
    Department of Genetics, South west National Primate Research Center, San Antonio, Texas, USA
    Clin Exp Pharmacol Physiol 37:178-84. 2010
    ....
  14. ncbi Impact of thrombocytopenia on survival of baboons with genetically modified pig liver transplants: clinical relevance
    B Ekser
    Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Am J Transplant 10:273-85. 2010
    ..If this problem can be resolved, we would anticipate that a pig liver could provide a period during which a patient in liver failure could be successfully bridged to allotransplantation...
  15. ncbi Baboon as a nonhuman primate model for vaccine studies
    Krishna K Murthy
    Department of Virology and Immunology, Southwest Foundation for Biomedical Research, 7620 N W Loop 410, Military Drive, San Antonio, TX 78227 5301, USA
    Vaccine 24:4622-4. 2006
    ..During the last two decades, numerous candidate vaccines have been evaluated in the baboon model...
  16. ncbi In vivo infusion of interleukin-1beta and chorionic gonadotropin induces endometrial changes that mimic early pregnancy events in the baboon
    Zuzana Strakova
    Department of Obstetrics and Gynecology, University of Illinois, 820 South Wood Street M C 808, Chicago, Illinois 60612 7313, USA
    Endocrinology 146:4097-104. 2005
    ..These changes suggest that infusion of IL-1beta at the time of implantation into the nonpregnant baboon treated with hCG synergizes with hCG and mimics the early endometrial events associated with the presence of an embryo...
  17. ncbi Efficacy of dietary arachidonic acid provided as triglyceride or phospholipid as substrates for brain arachidonic acid accretion in baboon neonates
    Vasuki Wijendran
    Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
    Pediatr Res 51:265-72. 2002
    ..0-fold greater from TG-AA than from PL-AA. We estimate that about half of postnatal brain AA accretion is derived from dietary preformed AA in term baboon neonates consuming a formula with lipid composition similar to that of human milk...
  18. ncbi Characterization of a CD46 transgenic pig and protection of transgenic kidneys against hyperacute rejection in non-immunosuppressed baboons
    Bruce E Loveland
    The Austin Research Institute, Heidelberg, Victoria, Australia
    Xenotransplantation 11:171-83. 2004
    ....
  19. pmc Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis
    Robert Silasi-Mansat
    Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK 73104, USA
    Blood 116:1002-10. 2010
    ....
  20. ncbi In vitro investigation of pig cells for resistance to human antibody-mediated rejection
    Hidetaka Hara
    Thomas E Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Transpl Int 21:1163-74. 2008
    ..Organs from GTKO/CD46 pigs are likely to be significantly less susceptible to CDC...
  21. pmc Identification of baboon microRNAs expressed in liver and lymphocytes
    Genesio M Karere
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, 7620 NW Loop 410, TX 78227, USA
    J Biomed Sci 17:54. 2010
    ..Evidence indicates that the baboon and human genomes are highly conserved; based on this conservation, we hypothesized that comparative genomic methods could be used to identify baboon miRNAs...
  22. ncbi Thrombotic thrombocytopenic purpura directly linked with ADAMTS13 inhibition in the baboon (Papio ursinus)
    Hendrik B Feys
    Laboratory for Thrombosis Research, Katholieke Universiteit Leuven Campus Kortrijk, Kortrijk, Belgium
    Blood 116:2005-10. 2010
    ..Here we report that 4 days of ADAMTS13 functional inhibition is sufficient to induce TTP in the baboon (Papio ursinus), in the absence of inciting triggers because injections with an inhibitory monoclonal antibody (mAb) ..
  23. ncbi Efficacy of a Gal-lectin subunit vaccine against experimental Entamoeba histolytica infection and colitis in baboons (Papio sp.)
    Mohamed D Abd Alla
    Department of Medicine, Medical College of Wisconsin, United States
    Vaccine 30:3068-75. 2012
    ..Release of xenic E. histolytica trophozoites (5×10(6)) into the small bowel of baboons (Papio sp...
  24. ncbi Tumor necrosis factor α induces a model of preeclampsia in pregnant baboons (Papio hamadryas)
    Neroli S Sunderland
    Vascular Immunology Laboratory, The Heart Research Institute, Newtown, New South Wales, Australia
    Cytokine 56:192-9. 2011
    ..and proteinuria) was induced by administration of low-dose TNF-α for 2weeks at mid-gestation in pregnant baboons (Papio hamadryas). Blood pressure was monitored continuously and remotely by intra-arterial radiotelemetry...
  25. ncbi The acoustic features of vowel-like grunt calls in chacma baboons (Papio cyncephalus ursinus): implications for production processes and functions
    M J Owren
    Department of Psychology, Reed College, Portland, Oregon 97202, USA
    J Acoust Soc Am 101:2951-63. 1997
    ..Further, cues related to vocal tract filtering appear particularly likely to play an important role in identifying individual calling animals...
  26. ncbi Identification of novel genes regulated by chorionic gonadotropin in baboon endometrium during the window of implantation
    J R A Sherwin
    HCLD, Professor of Physiology, Director, Center for Women s Health and Reproduction, Department of Obstetrics and Gynecology, University of Illinois, 820 South Wood Street, Chicago, Illinois 60612 7313, USA
    Endocrinology 148:618-26. 2007
    ..This study provides strong evidence that the preimplantation embryo itself influences the development of the receptive endometrium via secreted paracrine signals...
  27. pmc Efficient, long-term hepatic gene transfer using clinically relevant HDAd doses by balloon occlusion catheter delivery in nonhuman primates
    Nicola Brunetti-Pierri
    1Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA
    Mol Ther 17:327-33. 2009
    ..These results suggest that our minimally invasive method of delivery can significantly improve the vector's therapeutic index and may be a first step toward clinical application of HDAd for liver-directed gene therapy...
  28. pmc Is the new primate genus rungwecebus a baboon?
    Dietmar Zinner
    Cognitive Ethology, Deutsches Primatenzentrum, Gottingen, Germany
    PLoS ONE 4:e4859. 2009
    ..a limited sample of baboons of mainly unknown geographic origin, identified the kipunji as a sister taxon to Papio and not as a member of Lophocebus. Accordingly, the kipunji was separated into its own monotypic genus, Rungwecebus...
  29. pmc Effect of 30 per cent maternal nutrient restriction from 0.16 to 0.5 gestation on fetal baboon kidney gene expression
    L A Cox
    Department of Genetics, Southwest Foundation for Biomedical Research, 7620 NW Loop 410, San Antonio, TX 78227 5301, USA
    J Physiol 572:67-85. 2006
    ..These findings may have important implications for postnatal renal function, thereby contributing to the observed increased predisposition to hypertension and renal disease in the offspring of nutrient restricted mothers...
  30. ncbi Prevention of hyperacute rejection in a model of orthotopic liver xenotransplantation from pig to baboon using polytransgenic pig livers (CD55, CD59, and H-transferase)
    P Ramirez
    Liver Transplant Unit, Department of Surgery, Virgen Arrixaca University Hospital, Murcia, Spain
    Transplant Proc 37:4103-6. 2005
    ....
  31. pmc Genotype-by-diet effects on co-variation in Lp-PLA2 activity and LDL-cholesterol concentration in baboons fed an atherogenic diet
    Amanda Vinson
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX, USA
    J Lipid Res 49:1295-302. 2008
    ..We conclude that the pleiotropic QTLs detected at 2p24.3-p23.2 and 19q12-q13.2 on the basal and HCHF diets, respectively, exert diet-specific effects on covariation in Lp-PLA(2) activity and LDL-C concentration...
  32. pmc Gene expression profiling of alcoholic liver disease in the baboon (Papio hamadryas) and human liver
    Devanshi Seth
    Drug Health Services, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    Am J Pathol 163:2303-17. 2003
    ..The gene expression profile of ALD is dominated by alcohol metabolism and inflammation and differs from other liver diseases. Annexins may play a role in the progression of fibrosis in ALD...
  33. ncbi Psychology. Evolution of the social brain
    Robin Dunbar
    School of Biological Sciences, University of Liverpool, Liverpool L69 7ZB, UK
    Science 302:1160-1. 2003
  34. pmc Localization of multiple pleiotropic genes for lipoprotein metabolism in baboons
    David L Rainwater
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78245, USA
    J Lipid Res 50:1420-8. 2009
    ..Confirming the value of this approach, three of the QTL clusters replicated published linkage findings for the same or similar traits...
  35. ncbi Baboon model for West Nile virus infection and vaccine evaluation
    Roman F Wolf
    Department of Comparative Medicine Science, University of Oklahoma Health Sciences Center, USA
    Virology 355:44-51. 2006
    ..This report is the first to describe the development of the baboon model for WNV experimental infection and the utility of this model to characterize the immunologic response against WNV and a candidate WNV vaccine...
  36. ncbi Diet, plasma lipoproteins and experimental atherosclerosis in baboons (Papio sp.)
    R S Kushwaha
    Department of Physiology and Medicine, Southwest Foundation for Biomedical Research, San Antonio, TX 78245 0549, USA
    Hum Reprod Update 4:420-9. 1998
    ..The inhibitor peptide is a gene product and the presence of this peptide produces an antiatherogenic high HDL1 phenotype...
  37. ncbi Gravity is an important but secondary determinant of regional pulmonary blood flow in upright primates
    R W Glenny
    Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    J Appl Physiol (1985) 86:623-32. 1999
    ..Although important, gravity is not the predominant determinant of pulmonary perfusion heterogeneity in upright primates. Because of anatomic similarities, the same may be true for humans...
  38. pmc Integration of genetic and genomic methods for identification of genes and gene variants encoding QTLs in the nonhuman primate
    Laura A Cox
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78227, USA
    Methods 49:63-9. 2009
    ..This approach reduces the time and labor necessary to prioritize and identify genes and their polymorphisms influencing variation in a quantitative trait compared with traditional positional cloning methods...
  39. pmc Identification of candidate genes regulating HDL cholesterol using a chromosomal region expression array
    Laura A Cox
    Southwest Foundation for Biomedical Research, San Antonio, Texas 78227, USA
    Genome Res 12:1693-702. 2002
    ..This strategy is applicable to many species that serve as models for human diseases and can even be used with human subjects...
  40. ncbi The baboon as a non-human primate model of human schistosome infection
    M Nyindo
    Kilimanjaro Christian Medical College KCMC, Tumaini University, PO Box 2240, Moshi, Tanzania
    Parasitol Today 15:478-82. 1999
    ..They also address, in a general way, issues related to the use of non-human primates in biomedical research...
  41. ncbi Perspectives on the use of the baboon in embryology and teratology research
    A G Hendrickx
    California Regional Primate Research Center, University of California, Davis 95616 8542, USA
    Hum Reprod Update 3:575-92. 1997
    ..In this regard, a sample protocol is provided for the safety evaluation of biotechnology products using nonhuman primates, which are the most appropriate model for those compounds which are bioactive in species closely related to humans...
  42. pmc Natural Chagas disease in four baboons
    Jeff T Williams
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78245 0549, USA
    J Med Primatol 38:107-13. 2009
    ..It is a serious public health issue and the leading cause of heart disease and cardiovascular death in Central and South America. In 1984, a colony baboon was discovered to be infected with T. cruzi...
  43. ncbi Alterations in liver sinusoidal endothelium in a baboon model of type 1 diabetes
    H A Jamieson
    Centre for Education and Research on Ageing, Concord Hospital, Sydney, NSW, Australia
    Diabetologia 50:1969-76. 2007
    ..Potential diabetic changes in LSECs are important because of the role played by fenestrations in the LSECs in hepatic disposition of lipoproteins...
  44. pmc Treponema pallidum infection in the wild baboons of East Africa: distribution and genetic characterization of the strains responsible
    Kristin N Harper
    Department of Environmental Health Sciences, Columbia University Medical Center, New York, New York, United States of America
    PLoS ONE 7:e50882. 2012
    ..Further study is needed to elucidate the infection's transmission mode, its associated morbidity and mortality, and the relationship between baboon and human strains...
  45. pmc Identification of a QTL for adipocyte volume and of shared genetic effects with aspartate aminotransferase
    Tanushree Bose
    Department of Human Ecology, University of Texas at Austin, 78712, USA
    Biochem Genet 48:538-47. 2010
    ..These results suggest that omental adipocyte volume is under genetic regulation and that shared genetic factors influence adiposity-associated traits and AST...
  46. ncbi Structural and cellular architecture of conjunctival lymphoid follicles in the baboon (Papio anubis)
    Roger A Astley
    The Molecular Pathogenesis of Eye Infection Research Center, Dean A McGee Eye Institute, Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Exp Eye Res 76:685-94. 2003
    ..The present study was performed to delineate the structural and lymphoid anatomy of CLFs in the baboon (Papio anubis), a non-human primate conjunctival model with close similarity to the human...
  47. ncbi Clinical pig liver xenotransplantation: how far do we have to go?
    Burcin Ekser
    Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15261, USA
    Xenotransplantation 18:158-67. 2011
    ..If this problem can be resolved, a clinical trial of pig liver xenotransplantation as a bridge to allotransplantation may be both feasible and justified...
  48. ncbi The gamma-globin gene promoter progressively demethylates as the hematopoietic stem progenitor cells differentiate along the erythroid lineage in baboon fetal liver and adult bone marrow
    Mahipal Singh
    Jesse Brown VA Medical Center, Chicago, IL 60612, USA
    Exp Hematol 35:48-55. 2007
    ....
  49. ncbi Locus controlling LDL cholesterol response to dietary cholesterol is on baboon homologue of human chromosome 6
    Candace M Kammerer
    Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Arterioscler Thromb Vasc Biol 22:1720-5. 2002
    ..We performed linkage analyses to locate this QTL by using data on the baboon genetic linkage map...
  50. ncbi Identification of promoter variants in baboon endothelial lipase that regulate high-density lipoprotein cholesterol levels
    Laura A Cox
    Department of Genetics, Southwest National Primate Research Center, Southwest Foundation for Biomedical Research, 7620 NW Loop 410, San Antonio, TX 78227, USA
    Circulation 116:1185-95. 2007
    ..The mechanism by which LIPG variation influences HDL levels has not been determined...
  51. ncbi Evidence that ghrelin is as potent as growth hormone (GH)-releasing hormone (GHRH) in releasing GH from primary pituitary cell cultures of a nonhuman primate (Papio anubis), acting through intracellular signaling pathways distinct from GHRH
    Rhonda D Kineman
    Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA
    Endocrinology 148:4440-9. 2007
    ..Therefore, in the present study, primary pituitary cell cultures from female baboons (Papio anubis) were used as a model system to test the direct effects of ghrelin on primate somatotrope function...
  52. ncbi Liver xenografts for the treatment of acute liver failure: clinical and experimental experience and remaining immunologic barriers
    Hidetaka Hara
    Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, USA
    Liver Transpl 14:425-34. 2008
    ....
  53. ncbi Formula feeding potentiates docosahexaenoic and arachidonic acid biosynthesis in term and preterm baboon neonates
    Eszter Sarkadi-Nagy
    Division of Nutritional Sciences, Savage Hall, Cornell University, Ithaca, NY 14853
    J Lipid Res 45:71-80. 2004
    ..Current formula DHA concentrations are inadequate to normalize long-chain polyunsaturated fatty acids synthesis to that of breast-fed levels...
  54. pmc The innate immune response and activation of coagulation in alpha1,3-galactosyltransferase gene-knockout xenograft recipients
    Mohamed Ezzelarab
    Thomas E Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh, PA 15261, USA
    Transplantation 87:805-12. 2009
    ..The role of the innate immune system in the development of thrombotic microangiopathy (TM) after alpha1,3-galactosyltransferase gene-knockout (GTKO) pig organ transplantation in primates is uncertain...
  55. pmc Fetal blood sampling in baboons (Papio spp.): important procedural aspects and literature review
    S D Joy
    Department of Obstetrics and Gynecology, Wake Forest University, School of Medicine, Winston Salem, NC, USA
    J Med Primatol 38:151-5. 2009
    The baboons (Papio cynocephalus) have similarities with human placentation and fetal development...
  56. ncbi Cardiac xenotransplantation: recent preclinical progress with 3-month median survival
    Christopher G A McGregor
    Division of Cardiovascular Surgery, Department of Surgery, Mayo Clinic, Rochester, Minn 55905, USA
    J Thorac Cardiovasc Surg 130:844-51. 2005
    ..Overcoming the immune barrier to successful cardiac xenotransplantation is most appropriately first explored with the non-life-supporting heterotopic model...
  57. ncbi Normal concentrations of essential and toxic elements in pregnant baboons and fetuses (Papio species)
    N E Schlabritz-Loutsevitch
    Department of Comparative Medicine and Southwest National Primate Research Center, Southwest Foundation for Biomedical Research, San Antonio, TX 78224 5301, USA
    J Med Primatol 33:152-62. 2004
    ....
  58. ncbi Effect of 5-aza-2'-deoxycytidine (Dacogen) on covalent histone modifications of chromatin associated with the epsilon-, gamma-, and beta-globin promoters in Papio anubis
    Donald Lavelle
    Jesse Brown VA Medical Center and Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA
    Exp Hematol 34:339-47. 2006
    ..anubis) pre- and posttreatment...
  59. ncbi Gastroesophageal reflux disease in baboons (Papio sp.): a new animal model
    E J Glover
    Southwest National Primate Research Center, Southwest Foundation for Biomedical Research, San Antonio, TX 78245 0549, USA
    J Med Primatol 37:18-25. 2008
    ..An animal model that exhibits spontaneous GERD would provide the opportunity for much-needed research examining the susceptibility, diagnosis, and treatment of GERD...
  60. pmc Tissue factor-dependent coagulation is preferentially up-regulated within arterial branching areas in a baboon model of Escherichia coli sepsis
    Cristina Lupu
    Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, 825 NE 13 St, Oklahoma City, OK 73104, USA
    Am J Pathol 167:1161-72. 2005
    ..These data suggest that site-dependent endothelial heterogeneity and rheological factors contribute to focal procoagulant responses to E. coli...
  61. ncbi The role of anti-non-Gal antibodies in the development of acute humoral xenograft rejection of hDAF transgenic porcine kidneys in baboons receiving anti-Gal antibody neutralization therapy
    Gang Chen
    Department of Surgery, University of Western Ontario, London, Ontario, Canada
    Transplantation 81:273-83. 2006
    ..The present study was undertaken to determine the role of preformed and induced anti-non-Gal antibodies in the rejection of hDAF pig-to-baboon kidney xenotransplants after anti-Gal antibody neutralization therapy...
  62. ncbi Habitual cave use and thermoregulation in chacma baboons (Papio hamadryas ursinus)
    L Barrett
    Behavioural Ecology Research Group, University of Natal, Durban 4041, South Africa
    J Hum Evol 46:215-22. 2004
    ..Here we provide the first such data, on the frequency and patterning of the use of an underground cave system by baboons (Papio hamadryas)-and show that usage is determined, at least in part, by above-ground temperatures.
  63. ncbi Periodontal tissue regeneration by combined applications of recombinant human osteogenic protein-1 and bone morphogenetic protein-2. A pilot study in Chacma baboons (Papio ursinus)
    U Ripamonti
    Bone Research Unit, Medical Research Council University of the Witwatersrand, Medical School, Johannesburg, South Africa
    Eur J Oral Sci 109:241-8. 2001
    ..Twelve furcation defects prepared in the first and second mandibular molars of three adult baboons (Papio ursinus) were used to assess whether qualitative histological aspects of periodontal tissue regeneration could be ..
  64. ncbi Two major loci control variation in beta-lipoprotein cholesterol and response to dietary fat and cholesterol in baboons
    D L Rainwater
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Tex 78245 0549, USA
    Arterioscler Thromb Vasc Biol 18:1061-8. 1998
    ..Detection of these major loci with large effects on the LDLC response to dietary cholesterol in a nonhuman primate offers hope of detecting and ultimately identifying similar loci that determine LDLC variation in human populations...
  65. ncbi Highly abundant genes in the transcriptosome of human and baboon CD34 antigen-positive bone marrow cells
    I Gomes
    Department of Medicine, University of Illinois at Chicago, USA
    Blood 98:93-9. 2001
    ..The cDNAs reported here represent a selection of some of the most highly abundant genes in hematopoietic cells and provide a starting point to develop a profile of the transcriptosome of CD34(+) cells...
  66. ncbi siDNMT1 increases γ-globin expression in chemical inducer of dimerization (CID)-dependent mouse βYAC bone marrow cells and in baboon erythroid progenitor cell cultures
    Virryan Banzon
    Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA
    Exp Hematol 39:26-36.e1. 2011
    ..These studies were performed to test the hypothesis that DNMT1 is required for maintenance of DNA methylation and repression of the γ-globin gene in adult-stage erythroid cells...
  67. ncbi Kinda baboons (Papio kindae) and grayfoot chacma baboons (P. ursinus griseipes) hybridize in the Kafue river valley, Zambia
    C J Jolly
    New York University, Anthropology, New York, New York 10003, USA
    Am J Primatol 73:291-303. 2011
    The ranges of small kinda (Papio kindae) and much larger grayfooted chacma (P. ursinus griseipes) baboons adjoin in the Kafue National Park, Zambia...
  68. ncbi Fossil papio cranium from !Ncumtsa (Koanaka) Hills, western Ngamiland, Botswana
    Blythe A Williams
    Department of Evolutionary Anthropology, Duke University, Durham, NC 27708, USA
    Am J Phys Anthropol 149:1-17. 2012
    Three fossils, a cranium of Papio, a cercopithecid frontal bone, and a mandible of juvenile Papio, have been recovered from cave deposits in the !Ncumtsa (Koanaka) Hills of western Ngamiland, Botswana...
  69. ncbi Pregnancy-specific glycoprotein (PSG) in baboon (Papio hamadryas): family size, domain structure, and prediction of a functional region in primate PSGs
    G Q Zhou
    Department of Immunology, Umea University, SE 90185 Umeå, Sweden
    Biol Reprod 64:90-9. 2001
    ....
  70. ncbi Epidemiology of herpesvirus papio infection in a large captive baboon colony: similarities to Epstein-Barr virus infection in humans
    H B Jenson
    Departments of Pediatrics and Microbiology, University of Texas Health Science Center at San Antonio, 78229 3900, USA
    J Infect Dis 181:1462-6. 2000
    The epidemiology of herpesvirus papio, a lymphocryptovirus similar to Epstein-Barr virus (EBV), was studied in a captive colony of >1900 baboons. Herpesvirus papio IgG antibody titers were measured by IFA...
  71. ncbi Centre-embedded structures are a by-product of associative learning and working memory constraints: evidence from baboons (Papio Papio)
    Arnaud Rey
    Laboratoire de Psychologie Cognitive CNRS, Aix Marseille Universite, Marseille, France
    Cognition 123:180-4. 2012
    ....
  72. ncbi Induction of endochondral bone formation by recombinant human transforming growth factor-beta2 in the baboon (Papio ursinus)
    U Ripamonti
    Bone Research Laboratory, Medical Research Council University of the Witwatersrand, Medical School, Johannesburg, South Africa
    Growth Factors 17:269-85. 2000
    ..induces endochondral bone formation 30 days after implantation in heterotopic intramuscular sites of the baboon (Papio ursinus) at doses of 1, 5 and 25 microg per 100 mg of guanidinium-inactivated collagenous bone matrix as carrier...
  73. ncbi Zoonotic intestinal parasites in Papio anubis (baboon) and Cercopithecus aethiops (vervet) from four localities in Ethiopia
    Mengistu Legesse
    Institute of Pathobiology, Addis Ababa University, P O Box 1176, Addis Ababa, Ethiopia
    Acta Trop 90:231-6. 2004
    A total of 59 faecal samples from ranging Papio anubis (baboons) and another 41 from Cercopithecus aethiops (vervet) from the Rift Valley areas of Ethiopia were microscopically examined to determine the prevalence and species of major ..
  74. ncbi Physiological and molecular determinants of insulin action in the baboon
    Alberto O Chavez
    Diabetes Division, Department of Medicine, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr, San Antonio, TX 78229, USA
    Diabetes 57:899-908. 2008
    ..To quantitate insulin sensitivity in lean and obese nondiabetic baboons and examine the underlying cellular/molecular mechanisms responsible for impaired insulin action to characterize a baboon model of insulin resistance...
  75. ncbi Evolutionary inferences of novel simian T lymphotropic virus type 1 from wild-caught chacma (Papio ursinus) and olive baboons (Papio anubis)
    R Mahieux
    , Institut Pasteur, 28 rue du Dr Roux, Paris, Cedex 15, 75724, France
    Virology 251:71-84. 1998
    A serological survey of 22 wild-caught South African (Transvaal) chacma baboons (Papio ursinus) and eight olive baboons (Papio anubis) from Kenya indicates that 13 P. ursinus and one P...
  76. pmc An animal model for human EBV-associated hemophagocytic syndrome: herpesvirus papio frequently induces fatal lymphoproliferative disorders with hemophagocytic syndrome in rabbits
    K Hayashi
    Second Department of Pathology, Okayama University Medical School, 2 5 1 Shikata cho, Okayama City 700 8558, Japan
    Am J Pathol 158:1533-42. 2001
    ..These data indicate that the high rate of rabbit LPD with HPS induction is caused by HVP. This system is useful for studying the pathogenesis, prevention, and treatment of human EBV-AHS...
  77. ncbi Serum leptin levels in wild and captive populations of baboons (papio): implications for the ancestral role of leptin
    W A Banks
    Geriatric Research, Educational and Clinical Center, Veterans Affairs Medical Center St Louis, St Louis, Missouri 63106, USA
    J Clin Endocrinol Metab 86:4315-20. 2001
    ..We examined leptin levels in wild, East African populations of baboons (Papio anubis, P. hamadryas, and anubis/hamadryas hybrids)...
  78. pmc Genetics of primary cerebral gyrification: Heritability of length, depth and area of primary sulci in an extended pedigree of Papio baboons
    P Kochunov
    Research Imaging Institute, The University of Texas Health Science Center, San Antonio, TX 78229, USA
    Neuroimage 53:1126-34. 2010
    ..Our results imply that heritability of sulcal phenotypes may be regionally modulated by arcuate U-fiber systems. However, further research is necessary to unravel the complexity of genetic contributions to cortical morphology...
  79. ncbi Ranging behavior, group size and behavioral flexibility in Ethiopian hamadryas baboons (Papio hamadryas hamadryas)
    Larissa Swedell
    Queens College, City University of New York, NY, USA
    Folia Primatol (Basel) 73:95-103. 2002
    ..Overall, this study suggests that hamadryas baboons may be more flexible in some aspects of their behavioral ecology (e.g. group size) than in others (e.g. ranging behavior)...
  80. ncbi Pyramidal cell specialization in the occipitotemporal cortex of the Chacma baboon (Papio ursinus)
    Guy N Elston
    Vision, Touch and Hearing Research Centre, Dept of Physiology and Pharmacology, School of Biomedical Sciences and Queensland Brain Institute, The University of Queensland, Brisbane, QLD, 4072 Australia
    Exp Brain Res 167:496-503. 2005
    ....
  81. pmc Pathogenicity of different baboon herpesvirus papio 2 isolates is characterized by either extreme neurovirulence or complete apathogenicity
    Kristin M Rogers
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, Oklahoma 74078 2007, USA
    J Virol 77:10731-9. 2003
    ..Taken together, these results demonstrate that two subtypes of HVP2 exist that are very closely related but differ dramatically in their ability to cause disease in a murine model...
  82. pmc Modulation of the baboon (Papio anubis) uterine endometrium by chorionic gonadotrophin during the period of uterine receptivity
    A T Fazleabas
    Department of Obstetrics and Gynecology, University of Illinois, Chicago, IL 60612, USA
    Proc Natl Acad Sci U S A 96:2543-8. 1999
    ....
  83. ncbi Discriminating the relation between relations: the role of entropy in abstract conceptualization by baboons (Papio papio) and humans (Homo sapiens)
    J Fagot
    Comparative Cognition Research Group, Center for Research in Cognitive Neurosciences, 31 Chemin Joseph Aiguier, 13402 Marseille, France
    J Exp Psychol Anim Behav Process 27:316-28. 2001
    Two baboons (Papio papio) successfully learned relational matching-to-sample: They picked the choice display that involved the same relation among 16 pictures (same or different) as the sample display, although the sample display shared ..
  84. ncbi Neonatal chronic lung disease in extremely immature baboons
    J J Coalson
    Department of Pathology, University of Texas Health Science Center San Antonio, San Antonio, USA
    Am J Respir Crit Care Med 160:1333-46. 1999
    ..This model demonstrates that impaired alveolization and capillary development occur in immature lungs, even in the absence of marked hyperoxia and high ventilation settings...
  85. ncbi Proximate factors mediating "contact" calls in adult female baboons (Papio cynocephalus ursinus) and their infants
    D Rendall
    Department of Psychology, University of Pennsylvania, USA
    J Comp Psychol 114:36-46. 2000
    ..Field study of chacma baboons (Papio cynocephalus ursinus) revealed that contact barks in adult females were motivated by separation both from the ..
  86. pmc The influence of long chain polyunsaturate supplementation on docosahexaenoic acid and arachidonic acid in baboon neonate central nervous system
    Guan Yeu Diau
    Division of Nutritional Sciences, Cornell University, Ithaca, New York, USA
    BMC Med 3:11. 2005
    ..We quantitatively mapped fatty acids in 26 regions of the four-week-old breastfed baboon CNS, and studied the influence of dietary DHA and ARA supplementation and prematurity on CNS DHA and ARA concentrations...
  87. pmc Predictive models of insulin resistance derived from simple morphometric and biochemical indices related to obesity and the metabolic syndrome in baboons
    Alberto O Chavez
    Department of Medicine, Diabetes Division, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
    Cardiovasc Diabetol 8:22. 2009
    ..e. percent body fat by DXA and HbA1c). However, a simple method to screen and identify obese insulin resistant baboons for inclusion in interventional studies is not available...
  88. ncbi Characterization of baboon (Papio hamadryas) milk proteins
    A J Hall
    Australian Equine Blood Typing Research Laboratory, University of Queensland, Brisbane, Australia
    Biochem Genet 39:59-71. 2001
    ..beta LG and alpha LA polymorphisms with three (A, B, and C) and two (A and B) variants, respectively, were detected by immobiline IEF, pH 4-6, of individual baboon milk samples at varying stages of lactation...
  89. ncbi Pleiotropic effects of genes for insulin resistance on adiposity in baboons
    Guowen Cai
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78227 5301, USA
    Obes Res 12:1766-72. 2004
    ..Previous research has suggested a genetic contribution to the development of insulin resistance and obesity. We hypothesized that the same genes influencing insulin resistance might also contribute to the variation in adiposity...
  90. ncbi Staging of the pathophysiologic responses of the primate microvasculature to Escherichia coli and endotoxin: examination of the elements of the compensated response and their links to the corresponding uncompensated lethal variants
    F B Taylor
    Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City 73104, USA
    Crit Care Med 29:S78-89. 2001
    ..Review of primate studies of Escherichia coli sepsis and endotoxemia with a reexamination of the rationale for diagnosis and treatment of these multistage disorders...
  91. ncbi Cranial allometry, phylogeography, and systematics of large-bodied papionins (primates: Cercopithecinae) inferred from geometric morphometric analysis of landmark data
    Stephen R Frost
    Department of Anatomy, New York College of Osteopathic Medicine, Old Westbury, NY 11568, USA
    Anat Rec A Discov Mol Cell Evol Biol 275:1048-72. 2003
    The cranial morphology of the African Old World monkeys Mandrillus, Papio, and Theropithecus (i.e., baboons) has been the subject of a number of studies investigating their systematic relationships, patterns of scaling, and growth...
  92. ncbi Docosahexaenoic and arachidonic acid influence on preterm baboon retinal composition and function
    Guan Yeu Diau
    Division of Nutritional Sciences, Cornell University, Ithaca, New York 14853, USA
    Invest Ophthalmol Vis Sci 44:4559-66. 2003
    ..This study reports measurements of retinal long chain polyunsaturate (LCP) concentrations and electroretinogram (ERG) parameters for term and preterm neonatal baboons consuming clinically relevant diets...
  93. ncbi Same-different conceptualization by baboons (Papio papio): the role of entropy
    E A Wasserman
    Department of Psychology, University of Iowa and Center for Research in Cognitive Neurosciences, Iowa City 52242 1407, USA
    J Comp Psychol 115:42-52. 2001
    The authors trained 6 baboons (Papio papio) to make 1 of 2 report responses to 16-icon same arrays versus 16-icon different arrays...
  94. ncbi A genetic linkage map of the baboon (Papio hamadryas) genome based on human microsatellite polymorphisms
    J Rogers
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78245, USA
    Genomics 67:237-47. 2000
    A first-generation genetic linkage map of the baboon (Papio hamadryas) genome was developed for use in biomedical and evolutionary genetics...
  95. ncbi Measurement of pulmonary flow reserve in higher primates
    Rahn Ilsar
    Cardiology Department, Royal Prince Alfred Hospital, Camperdown, Australia
    Clin Exp Pharmacol Physiol 36:797-802. 2009
    ..Measurements of PFR may facilitate pulmonary microvascular assessments...
  96. ncbi Mitochondrial evidence for the origin of hamadryas baboons
    Derek E Wildman
    Department of Anthropology, New York Univesity, USA
    Mol Phylogenet Evol 32:287-96. 2004
    Baboons (Mammalia: Primates, Papio) are found primarily on the continent of Africa, but the range of hamadryas baboons (Papio hamadryas) extends to the Arabian Peninsula, and the origin of Arabian populations is unclear...
  97. ncbi The endothelial cell protein C receptor aids in host defense against Escherichia coli sepsis
    F B Taylor
    Oklahoma Medical Research Foundation OMRF, Oklahoma City 73104, USA
    Blood 95:1680-6. 2000
    ..Blood. 2000;95:1680-1686)..
  98. pmc Effects of a patent ductus arteriosus on postprandial mesenteric perfusion in premature baboons
    Donald McCurnin
    Department of Pediatrics, University of Texas Health Science Center and Soutwest Foundation for Biomedical Research, San Antonio, TX, USA
    Pediatrics 122:e1262-7. 2008
    ..Although a patent ductus arteriosus can affect superior mesenteric artery perfusion in nonfeeding infants, there is no information about its effects on the hyperemic response that follows a feeding...
  99. ncbi Mitochondrial phylogeny and systematics of baboons (Papio)
    Timothy K Newman
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78227, USA
    Am J Phys Anthropol 124:17-27. 2004
    Baboons (Papio, s.s.) comprise a series of parapatric allotaxa (subspecies or closely related species) widely distributed in sub-Saharan Africa...
  100. ncbi Efficacy of anti-tumor necrosis factor therapy in the treatment of spontaneous endometriosis in baboons
    Breton F Barrier
    Southwest Foundation for Biomedical Research, San Antonio, TX, USA
    Fertil Steril 81:775-9. 2004
    ..To determine the efficacy of anti-tumor necrosis factor therapy (etanercept) for treating endometriosis in baboons...
  101. ncbi Sequential loss of two neighboring exons of the tropoelastin gene during primate evolution
    Z Szabo
    Pacific Biomedical Research Center, University of Hawaii, Honolulu, HI 96822, USA
    J Mol Evol 49:664-71. 1999
    ..Loss of both exons was probably facilitated by Alu-mediated recombination events and possibly conferred a functional evolutionary advantage in elastic tissue...

Research Grants64

  1. Functional Analysis of PAAN-AG5, the Baboon Counterpart of HLA-G5
    Daudi K Langat; Fiscal Year: 2010
    ..We have been assessing the suitability of using the olive baboon (Papio anubis) as a model for HLA-G in vivo studies...
  2. STRUCTURAL NEUROCHEMISTRY OF RETINAL CIRCUITS
    Robert E Marc; Fiscal Year: 2013
    ..Aim 2. Generate a 100 TB connectome for the baboon Papio Anubis retina. ...
  3. Conference Support: NHP Models of Aging
    Joseph Kemnitz; Fiscal Year: 2001
    ..Callithrix jacchus), squirrel monkeys (Saimiri sciureus), cynomolgus monkeys (Macaca fascicularis), baboons (Papio hamadryas), and chimpanzees (Pan troglodytes). A working dinner will be held on the evening of May 31...
  4. Baboon Model for Genetics of Human Generalized Epilepsy
    Jeff Williams; Fiscal Year: 2007
    ..baboon colony at Southwest Foundation for Biomedical Research (SFBR) in San Antonio, TX, to develop the baboon (Papio hamadryas anubis, Papio hamadryas cynocephalus, and their hybrids) as a nonhuman primate model for the genetics of ..
  5. THE ROLE OF THE SERTOLI CELL IN SPERMATOGENESIS
    Martin Dym; Fiscal Year: 1980
    ..We propose to examine the reproductive system of an ape - the baboon (Papio anubis) - using light and electron microscopy...
  6. Periodontitis and Preterm Birth:Nonhuman Primate Model
    Jeffrey Ebersole; Fiscal Year: 2006
    ..The baboon, Papio anubis, which has a >95 percent genetic homology to humans will be used to investigate Aims testing hypotheses ..
  7. Genetics of Monoamine Endophenotypes and Mental Health
    Jeffrey Rogers; Fiscal Year: 2006
    ..In this project, we propose to conduct a whole genome linkage scan in a nonhuman primate model (baboons, Papio hamadryas)...
  8. EFFECTS OF ABUSED DRUGS ON PERCEPTION: AN ANIMAL MODEL
    ROBERT HIENZ; Fiscal Year: 2004
    ..on perceptual processes within the broader context of the social communication systems of the savanna baboon, Papio cynocephalus...
  9. Ventilation Model and CNS Injury in Baboons with Bronchopulmonary Dysplasia
    Terrie Inder; Fiscal Year: 2007
    ..In this study we propose to investigate the nature of cerebral injury in a prematurely born primate model (Papio sp) developed as a model of bronchopulmonary dysplasia, utilizing both magnetic resonance imaging (MR) and ..
  10. EXTRAMURAL RESEARCH FACILITIES CONSTRUCTION PROJECTS
    FRANK WAXMAN; Fiscal Year: 1999
    The University of Oklahoma Health Sciences Center (OUHSC) has maintained a baboon (Papio hamadryas spp.) breeding and research program for over 40 years...
  11. A cDNA Sequence Resource for Baboon
    Roger Bumgarner; Fiscal Year: 2009
    ..Of these, approximately 1,532 sequences were obtained from Papio anubis (olive baboon) and 639 were obtained from Papio hamadryas (hamadryas baboon)...
  12. Social behavior and vocal communication in baboons
    THORE BERGMAN; Fiscal Year: 2004
    ..aims are to examine the acoustic properties and social function of vocalizations among free-ranging baboons (Papio cynocephalus ursinus). Research is conducted in the Moremi Game Reserve, Botswana...
  13. VOCAL COMMUNICATION AND BEHAVIOR
    Dorothy Cheney; Fiscal Year: 2006
    ..Subjects are free-ranging baboons (Papio cyncephalus ursinus) in the Okavango Delta, Botswana...
  14. ALZHEIMER PROTEINS DURING BRAIN METABOLIC STRESS
    Warren Selman; Fiscal Year: 1999
    ..evaluate the cellular expression patterns of APP and Abeta in the damaged and non-damaged regions of the baboon (papio anubis) brain...
  15. MECHANISMS FOR EBV EBNA-2 IMMORTALIZING FUNCTION
    Paul Ling; Fiscal Year: 2000
    ..and are conserved among the EBNA-2 types (from EBV-1 and EBV-2), including the EBNA-2 homologue from herpesvirus papio (HVP). Several questions still remain unsolved...
  16. IV COCAINE ABUSE TREATMENT: A LABORATORY MODEL
    RICHARD FOLTIN; Fiscal Year: 2007
    ..abstract_text> ..
  17. LABORATORY ANALYSIS OF COCAINE ABSTINENCE
    RICHARD FOLTIN; Fiscal Year: 2007
    ..abstract_text> ..
  18. A BABOON MODEL FOR THE GENETICS OF CORTICAL BONE MATERIAL PROPERTIES
    LORENA HAVILL; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  19. Radiotracer R and D in Nuclear Medicine and Neuroscience
    Yu Shin Ding; Fiscal Year: 2006
    ..abstract_text> ..
  20. 2004 Reproductive Tract Biology Gordon Conference
    Asgerally Fazleabas; Fiscal Year: 2004
    ..The continued ability to meet with the Mammalian Gametogenesis and Embryogenesis Conference at the same site will further enhance the quality of this meeting, which has consistently been highly rated by the attendees. ..
  21. DECIDUALIZATION IN THE BABOON
    Asgerally Fazleabas; Fiscal Year: 2003
    ....
  22. PATHOGENIC MECHANISMS AND INTERVENTION STRATEGIES IN HUS
    Richard Siegler; Fiscal Year: 2002
    ....
  23. Multidisciplinary Program in Female and Male Reproduction
    EUGENE ALBRECHT; Fiscal Year: 2008
    ..The discoveries obtained in the baboon primate model are expected to translate to the human to advance knowledge of human reproductive biology. [unreadable] [unreadable]..
  24. Calorie Restriction Effects on Chromosomal Aberrations
    CHARLEEN MOORE; Fiscal Year: 2003
    ..The results will be essential in identifying potential mechanisms by which CR acts in cancer prevention and delay of the aging process in long-lived species such as the rhesus monkey and humans. ..
  25. Cell Differentation During Decidualization
    Zuzana Strakova; Fiscal Year: 2010
    ..Thus, in the long term our studies might provide new targets of intervention leading to improvements in diagnosis and treatment. ..
  26. Functional Analysis of GABAerglc Sedative/Anxiolytics
    NANCY ATOR; Fiscal Year: 2007
    ..abstract_text> ..
  27. Pharmacokinetics of SSRIs in Pregnancy
    Marianne Garland; Fiscal Year: 2008
    ..Research will identify drugs that have the least impact on the fetus, reduced impact on post-natal development without restricting treatment of maternal depression. [unreadable] [unreadable] [unreadable]..
  28. REGULATION OF CELL DIFFERENTATION DURING DECIDUALIZATION
    Zuzana Strakova; Fiscal Year: 2002
    ..We anticipate that our ongoing studies will contribute to find therapies to treat endometrial dysfunctions associated with infertility, habitual abortions and/or insufficient placental development. ..
  29. GLUCURONYL TRANSFERASE ACTIVITY IN THE FETAL PRIMATE
    Marianne Garland; Fiscal Year: 2004
    ..The long-term goal of this research is to reverse a trend which left the fetus as a therapeutic orphan. ..
  30. Dopamine D1 Effects on Blood Flow, Metabolism, and BOLD
    Kevin Black; Fiscal Year: 2004
    ..abstract_text> ..
  31. GENE EXPRESSION AND METHAMPHETAMINE NEUROTOXICITY
    George Ricaurte; Fiscal Year: 2002
    ..abstract_text> ..
  32. ADHD Treatment & Amphetamine Neurotoxicity
    George Ricaurte; Fiscal Year: 2007
    ....
  33. MDMA Neurotoxicity in Nonhuman Primates
    George Ricaurte; Fiscal Year: 2005
    ..abstract_text> ..
  34. SAFETY ASSESSMENT OF FENFLURAMINE/PHENTERMINE
    George Ricaurte; Fiscal Year: 2001
    ....
  35. Regulation of Microvascular Development in BPD
    William Maniscalco; Fiscal Year: 2006
    ..New data from this proposal will be essential for developing novel therapies for BPD. ..
  36. Methamphetamine Neurotoxicity in Nonhuman Primates
    George Ricaurte; Fiscal Year: 2006
    ....
  37. MDMA Neurotoxicity in Humans: Occurence & Consequences
    George Ricaurte; Fiscal Year: 2006
    ....
  38. NITROXIDERGIC CEREBROVASCULAR TONE DURING ANESTHESIA
    Shailendra Joshi; Fiscal Year: 2005
    ..abstract_text> ..
  39. New PET radioligand for the serotonin transporter
    Yiyun Huang; Fiscal Year: 2007
    ..Introduction of [18F]AFM would constitute the first PET tracer for the SERT that can be prepared in a central facility and distributed to various sites for clinical imaging purposes. ..
  40. Expanding WNPRC Resources for AIDS-Related Research
    Joseph Kemnitz; Fiscal Year: 2007
    ..Completing this renovation will provide the critical space necessary for the SIV program to expand at the WNPRC and for the investigators to continue their ground-breaking research. [unreadable] [unreadable] [unreadable]..
  41. Prion Transport Across the Blood-Brain Barrier
    William Banks; Fiscal Year: 2009
    ..To cause disease, prions must cross the blood-brain barrier to enter the brain. We will determine how prions cross the BBB. Knowing how prions enter the brain should lead to strategies on how to prevent prion diseases. ..
  42. Gas phase derivatization for lipidomic MS analysis
    JAMES BRENNA; Fiscal Year: 2007
    ....
  43. LCPUFA Status and Birth Outcome in India
    JAMES BRENNA; Fiscal Year: 2007
    ..Positive results would justify an intervention studies to include LCPUFA in the diets of pregnant women in developed and developing countries. ..
  44. Gene therapy for Fanconi anemia
    Hans Peter Kiem; Fiscal Year: 2009
    ..Our ultimate goal is to improve or cure the hematopoietic symptoms in FA patients by lentivirus-mediated HSC gene transfer, and develop methodologies that would be applicable to other genetic disorders and hematological diseases. ..
  45. Cord Blood Expansion and Transplantation in a Nonhuman Primate Model
    Hans Peter Kiem; Fiscal Year: 2009
    ....
  46. Thromboregulation to Prevent Thrombotic Microangiopathy
    David Cooper; Fiscal Year: 2008
    ..It is anticipated that these approaches will abrogate the development of TM and allow long-term survival of pig organs in baboons. ..
  47. Development of PET radioligands for cerebral cannabinoid receptor (CB1)
    ANDREW HORTI; Fiscal Year: 2008
    ....
  48. Opiate Addiction and HIV-1 Induced Release of Cytokines
    William Banks; Fiscal Year: 2006
    ....
  49. COMPARATIVE MEDICINE RESOURCE CENTER DIRECTORS MEETING
    Jeffrey Rogers; Fiscal Year: 2002
    ..abstract_text> ..
  50. Schistosome Calpain as a Vaccine Candidates
    Afzal Siddiqui; Fiscal Year: 2002
    ..Of greater importance, these studies should provide new insight into immune mechanisms which can damage worm parasites and establish a model by which to subsequently study the effector mechanisms. ..
  51. Conference on Autoimmunity & Tolerance In Renal Disease
    Jeffrey Platt; Fiscal Year: 2003
    ....
  52. Cue-Reactivity and Alcohol Self-Dosing
    Elise Weerts; Fiscal Year: 2003
    ..This research will additionally provide important information on the behavioral processes underlying conditioned responses to drug-related cues in animals which may be relevant to cue-reactivity and drug-taking in humans. ..
  53. Neurochemistry of Nicotine Dependence in Schizophrenia
    Wynne Schiffer; Fiscal Year: 2004
    ..Or increase inhibitory activity with the GABA agonist, gamma-vinyl GABA, prior to the nicotine challenge. We hope to guide the development of novel therapies for dual-diagnosis schizophrenia. ..
  54. Hematopoietic Potential of Muscle-Derived Cells
    Hans Peter Kiem; Fiscal Year: 2004
    ..abstract_text> ..
  55. PTS1 Regulation of Brain Met Enk Levels in Alcoholism
    William Banks; Fiscal Year: 2004
    ..abstract_text> ..
  56. Inhibition of HIV by Novel Chimeric Receptors
    Jonathan Allan; Fiscal Year: 2004
    ..If successful, this strategy will have broad applications in immunotherapy and immune reconstitution against HIV-1. ..
  57. RADIOTRACER R & D IN NUCLEAR MEDICINE AND NEUROSCIENCES
    Joanna Fowler; Fiscal Year: 2004
    ....
  58. NO, Genotype Dependent & Environment Specific Regulation
    Xing Li Wang; Fiscal Year: 2004
    ....
  59. PRECISE ISOTOPE RATIO CHROMATOGRAPHY AND STABLE TRACERS
    JAMES BRENNA; Fiscal Year: 2004
    ..The successful accomplishment of these plans will yield new tools and experimental approaches for investigation of the impact of developmental factors and recent physiological history on development of chronic disease. ..
  60. Determinants of Natural Host Resistance to SIV agm
    Jonathan Allan; Fiscal Year: 2005
    ..In summary, this proposal seeks to understand the role of coreceptor expression, viral replication and cellular immunity in the pathogenesis of SIV. ..
  61. Studies on the role of GABA in Cocaine Addiction
    Elise Weerts; Fiscal Year: 2005
    ..The results of these studies will increase our understanding of the role of GABA in the behavioral effects of cocaine and may lead to the development of better medications for the treatment of cocaine addiction. ..
  62. DIETARY ESSENTIAL FATTY ACID ACCUMULATION IN RETINA
    JAMES BRENNA; Fiscal Year: 2002
    ..Sub-normal development will be directly revealed via functional tests to assess the impact of low omega-3 fatty acid status on develop of vision acid status on development of vision and related health parameters. ..
  63. MGMT-Mediated in vivo Selection in a Large Animal Model
    Hans Peter Kiem; Fiscal Year: 2006
    ..These experiments will provide a platform for studies using gene-modified allogeneic stem cells to improve nonmyeloablative transplant strategies. ..
  64. RADIOTRACER R & D IN NUCLEAR MEDICINE AND NEUROSCIENCES
    Joanna Fowler; Fiscal Year: 2002
    ....