theileria

Summary

Summary: A genus of tick-borne protozoa parasitic in the lymphocytes, erythrocytes, and endothelial cells of mammals. Its organisms multiply asexually and then invade erythrocytes, where they undergo no further reproduction until ingested by a transmitting tick.

Top Publications

  1. ncbi Molecular studies on Babesia, Theileria and Hepatozoon in southern Europe. Part I. Epizootiological aspects
    A Criado-Fornelio
    Laboratory of Parasitology, Microbiology and Parasitology Department, Faculty of Pharmacy, University of Alcala de Henares, 28871, Alcala de Henares, Spain
    Vet Parasitol 113:189-201. 2003
  2. ncbi Detection of haemoparasites in cattle by reverse line blot hybridisation with a note on the distribution of ticks in Sicily
    K Georges
    Division of Parasitology and Tropical Veterinary Medicine, Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80.165, 3508 TD Utrecht, The Netherlands
    Vet Parasitol 99:273-86. 2001
  3. ncbi Detection of Theileria and Babesia species in ticks collected from cattle
    A Ica
    Department of Parasitology, Faculty of Veterinary Medicine, University of Erciyes, 38090 Kayseri, Turkey
    Vet Parasitol 148:156-60. 2007
  4. ncbi A review of nucleic-acid-based diagnostic tests for Babesia and Theileria, with emphasis on bovine piroplasms
    A Criado-Fornelio
    Parasitology Laboratory, Microbiology and Parasitology Department, University of Alcala, Alcala de Henares, Spain
    Parassitologia 49:39-44. 2007
  5. ncbi Divergence of the mitochondrial genome structure in the apicomplexan parasites, Babesia and Theileria
    Kenji Hikosaka
    Laboratory of Malariology, International Research Center of Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan
    Mol Biol Evol 27:1107-16. 2010
  6. pmc The transforming parasite Theileria co-opts host cell mitotic and central spindles to persist in continuously dividing cells
    Conrad von Schubert
    Molecular Pathobiology, DCR VPH, Vetsuisse Faculty, University of Bern, Bern, Switzerland
    PLoS Biol 8:. 2010
  7. ncbi Alteration of host cell phenotype by Theileria annulata and Theileria parva: mining for manipulators in the parasite genomes
    Brian Shiels
    Division of Veterinary Infection and Immunity, Parasitology Group, Institute of Comparative Medicine, Faculty of Veterinary Medicine, Bearsden Rd, Glasgow G61 1QH, UK
    Int J Parasitol 36:9-21. 2006
  8. ncbi Sequence heterogeneity in the 18S rRNA gene within Theileria equi and Babesia caballi from horses in South Africa
    Raksha Bhoora
    Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa
    Vet Parasitol 159:112-20. 2009
  9. ncbi Cell invasion by Theileria sporozoites
    Michael K Shaw
    G452 Stopford Building, School of Biological Sciences, University of Manchester, Oxford Road, Manchester, UK, M13 9PT
    Trends Parasitol 19:2-6. 2003
  10. pmc Consistent and contrasting properties of lineage-specific genes in the apicomplexan parasites Plasmodium and Theileria
    Chih Horng Kuo
    Department of Genetics, University of Georgia, Athens, GA 30602, USA
    BMC Evol Biol 8:108. 2008

Research Grants

Detail Information

Publications213 found, 100 shown here

  1. ncbi Molecular studies on Babesia, Theileria and Hepatozoon in southern Europe. Part I. Epizootiological aspects
    A Criado-Fornelio
    Laboratory of Parasitology, Microbiology and Parasitology Department, Faculty of Pharmacy, University of Alcala de Henares, 28871, Alcala de Henares, Spain
    Vet Parasitol 113:189-201. 2003
    Molecular epizootiology of piroplasmids (Babesia spp., Theileria spp.) and Hepatozoon canis was studied in mammals from southern Europe (mainly from Spain, but also from Portugal and France)...
  2. ncbi Detection of haemoparasites in cattle by reverse line blot hybridisation with a note on the distribution of ticks in Sicily
    K Georges
    Division of Parasitology and Tropical Veterinary Medicine, Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80.165, 3508 TD Utrecht, The Netherlands
    Vet Parasitol 99:273-86. 2001
    ..polymerase chain reaction (PCR) amplified regions of 16S rRNA (Ehrlichia/Anaplasma group) or 18S rRNA (Babesia/Theileria group) genes of haemoparasites detected Theileria annulata, T. buffeli/orientalis, Babesia bovis, B. bigemina, B...
  3. ncbi Detection of Theileria and Babesia species in ticks collected from cattle
    A Ica
    Department of Parasitology, Faculty of Veterinary Medicine, University of Erciyes, 38090 Kayseri, Turkey
    Vet Parasitol 148:156-60. 2007
    The present study was carried out to detect tick species that infest cattle, and Theileria and Babesia species transmitted by these ticks in Kayseri province (Turkey). A total of 300 cattle were examined for tick infestations...
  4. ncbi A review of nucleic-acid-based diagnostic tests for Babesia and Theileria, with emphasis on bovine piroplasms
    A Criado-Fornelio
    Parasitology Laboratory, Microbiology and Parasitology Department, University of Alcala, Alcala de Henares, Spain
    Parassitologia 49:39-44. 2007
    ..Special attention is given to Babesia and Theileria species infecting livestock...
  5. ncbi Divergence of the mitochondrial genome structure in the apicomplexan parasites, Babesia and Theileria
    Kenji Hikosaka
    Laboratory of Malariology, International Research Center of Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan
    Mol Biol Evol 27:1107-16. 2010
    ..The closely related genera Babesia and Theileria also have small mt genomes (6.6 kb) that are monomeric linear with an organization distinct from Plasmodium...
  6. pmc The transforming parasite Theileria co-opts host cell mitotic and central spindles to persist in continuously dividing cells
    Conrad von Schubert
    Molecular Pathobiology, DCR VPH, Vetsuisse Faculty, University of Bern, Bern, Switzerland
    PLoS Biol 8:. 2010
    The protozoan parasite Theileria inhabits the host cell cytoplasm and possesses the unique capacity to transform the cells it infects, inducing continuous proliferation and protection against apoptosis...
  7. ncbi Alteration of host cell phenotype by Theileria annulata and Theileria parva: mining for manipulators in the parasite genomes
    Brian Shiels
    Division of Veterinary Infection and Immunity, Parasitology Group, Institute of Comparative Medicine, Faculty of Veterinary Medicine, Bearsden Rd, Glasgow G61 1QH, UK
    Int J Parasitol 36:9-21. 2006
    The apicomplexan parasites Theileria annulata and Theileria parva cause severe lymphoproliferative disorders in cattle...
  8. ncbi Sequence heterogeneity in the 18S rRNA gene within Theileria equi and Babesia caballi from horses in South Africa
    Raksha Bhoora
    Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa
    Vet Parasitol 159:112-20. 2009
    ..A total of 488 samples were tested for the presence of Theileria equi and/or Babesia caballi using the reverse line blot hybridization assay...
  9. ncbi Cell invasion by Theileria sporozoites
    Michael K Shaw
    G452 Stopford Building, School of Biological Sciences, University of Manchester, Oxford Road, Manchester, UK, M13 9PT
    Trends Parasitol 19:2-6. 2003
  10. pmc Consistent and contrasting properties of lineage-specific genes in the apicomplexan parasites Plasmodium and Theileria
    Chih Horng Kuo
    Department of Genetics, University of Georgia, Athens, GA 30602, USA
    BMC Evol Biol 8:108. 2008
    ..In parasitic organisms, lineage-specific gene products are possible targets for vaccine development or therapeutics when these genes are absent from the host genome...
  11. ncbi Prevalence and incidence of tick-borne diseases in smallholder farming systems in the western-Kenya highlands
    O S Okuthe
    National Veterinary Research Centre, Kenya Agricultural Research Institute NVRC KARI, PO Box 32, Kikuyu, Kenya
    Vet Parasitol 141:307-12. 2006
    ..05). The difference in disease frequencies in two areas in close proximity shows the importance of monitoring disease events in order to understand and advice farmers in different production and farming systems appropriately...
  12. ncbi Estimating seroprevalence and variation to four tick-borne infections and determination of associated risk factors in cattle under traditional mixed farming system in Mbeere District, Kenya
    J M Gachohi
    International Livestock Research Institute ILRI, Old Naivasha Rd, Kabete, P O Box 30709 00100, Nairobi, Kenya
    Prev Vet Med 95:208-23. 2010
    A cross-sectional study of serum antibody responses of cattle to tick-borne disease (TBD) parasites (Theileria parva, Theileria mutans, Anaplasma marginale and Babesia bigemina) was conducted on traditional smallholder mixed farms in ..
  13. ncbi Development and evaluation of real-time PCR assays for the quantitative detection of Babesia caballi and Theileria equi infections in horses from South Africa
    Raksha Bhoora
    Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, South Africa
    Vet Parasitol 168:201-11. 2010
    ..000114% parasitized erythrocytes (PE). We further evaluated a previously reported Theileria equi-specific qPCR assay and showed that it was able to detect the 12 T...
  14. ncbi Repeated high dose imidocarb dipropionate treatment did not eliminate Babesia caballi from naturally infected horses as determined by PCR-reverse line blot hybridization
    C M Butler
    Department of Equine Sciences, Medicine Section, Utrecht University, PO Box 80 153, 3508 TD Utrecht, The Netherlands
    Vet Parasitol 151:320-2. 2008
    ..caballi and all horses had antibodies to Theileria equi...
  15. pmc Comparative genome analysis of three eukaryotic parasites with differing abilities to transform leukocytes reveals key mediators of Theileria-induced leukocyte transformation
    Kyoko Hayashida
    Division of Collaboration and Education, Research Center for Zoonosis Control, Hokkaido University, Sapporo, Hokkaido, Japan
    MBio 3:e00204-12. 2012
    We sequenced the genome of Theileria orientalis, a tick-borne apicomplexan protozoan parasite of cattle. The focus of this study was a comparative genome analysis of T. orientalis relative to other highly pathogenic Theileria species, T...
  16. pmc Molecular characterization of Theileria species associated with mortality in four species of African antelopes
    A M Nijhof
    Division of Parasitology and Tropical Veterinary Medicine, Faculty of Veterinary Medicine, Utrecht University, P O Box 80 165, 3508 TD Utrecht, The Netherlands
    J Clin Microbiol 43:5907-11. 2005
    ..We developed Theileria species-specific probes used in combination with reverse line blot hybridization assays and identified three ..
  17. ncbi Identification, genetic diversity and prevalence of Theileria and Babesia species in a sheep population from Northern Spain
    Daniel Nagore
    Department of Animal Health, Instituto Vasco de Investigación y Desarrollo Agrario Berreaga 1, 48160 Derio, Bizkaia, Spain
    Int J Parasitol 34:1059-67. 2004
    The genetic diversity and prevalence of virtually all Theileria and Babesia species in a sheep population were studied using a specifically designed reverse line blot macroarray...
  18. ncbi Identification of different Theileria species (Theileria lestoquardi, Theileria ovis, and Theileria annulata) in naturally infected sheep using nested PCR-RFLP
    Mahdieh Zaeemi
    Department of Clinical Science, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
    Parasitol Res 108:837-43. 2011
    ..A nested PCR-restriction fragment length polymorphism (RFLP) was carried out to identification Theileria species in sheep in some area in western half of Iran (Sari, Rasht, Urmia, Ilam, and Ahvaz)...
  19. pmc TGF-b2 induction regulates invasiveness of Theileria-transformed leukocytes and disease susceptibility
    Marie Chaussepied
    Institut Cochin, Universite Paris Descartes, Paris, France
    PLoS Pathog 6:e1001197. 2010
    b>Theileria parasites invade and transform bovine leukocytes causing either East Coast fever (T. parva), or tropical theileriosis (T. annulata)...
  20. ncbi Phylogeny and evolution of the piroplasms
    M T Allsopp
    Onderstepoort Veterinary Institute, South Africa
    Parasitology 108:147-52. 1994
    Small subunit ribosomal RNA (srRNA) genes of three Theileria species, one Cytauxzoon and four Babesia species were amplified using the polymerase chain reaction (PCR), cloned and sequenced...
  21. ncbi Theileria-induced leukocyte transformation
    Dirk A E Dobbelaere
    Division of Molecular Pathology, Institute of Animal Pathology, University of Bern, Langgassstrasse 122, CH 3012 Bern, Switzerland
    Curr Opin Microbiol 6:377-82. 2003
    The intracellular protozoan parasites Theileria parva and T. annulata transform the cells they infect, inducing uncontrolled proliferation...
  22. ncbi Ixodes hexagonus is the main candidate as vector of Theileria annae in northwest Spain
    A T Camacho
    Laboratorio Lema and Bandin, C Lepanto, 5 Bajo, 36201 Vigo, Spain
    Vet Parasitol 112:157-63. 2003
    ..Because the 18SrDNA sequence was not completely identical to that of B. microti, the new name "Theileria annae" was assigned to the canine agent...
  23. ncbi An overview of the Babesia, Plasmodium and Theileria genomes: a comparative perspective
    Audrey O T Lau
    Program in Genomics, Department of Veterinary Microbiology and Pathology, School for Global Animal Health, College of Veterinary Medicine, Washington State University, Pullman, WA 99164 7040, USA
    Mol Biochem Parasitol 164:1-8. 2009
    Babesia, Plasmodium and Theileria form a triad of apicomplexan hemoparasites and are accountable for significant mortality and morbidity to humans and animals globally...
  24. ncbi Intracellular survival of apicomplexan parasites and host cell modification
    Carsten G K Lüder
    Institute for Medical Microbiology, Georg August University Gottingen, Kreuzbergring 57, 37075 Gottingen, Germany
    Int J Parasitol 39:163-73. 2009
    ..made in understanding the molecular details of these parasite-dependent effects for Plasmodium-, Toxoplasma- and Theileria-infected cells...
  25. ncbi Bovine piroplasms in Minorca (Balearic Islands, Spain): a comparison of PCR-based and light microscopy detection
    S Almeria
    Parasitology, Faculty Veterinary Medicine, Autonomous University of Barcelona, Barcelona, Spain
    Vet Parasitol 99:249-59. 2001
    The present study provides the first epidemiological data regarding infection by Theileria and Babesia piroplasms in cattle in Minorca. More than 94% of the studied animals were positive for the presence of Theileria sp...
  26. ncbi Application of a reverse line blot assay to the study of haemoparasites in cattle in Uganda
    C A L Oura
    Department of Microbiology and Parasitology, Faculty of Vet Medicine, Makerere University, Kampala, Uganda
    Int J Parasitol 34:603-13. 2004
    ..A critical question is the sensitivity, particularly in relation to detecting carrier animals. As Theileria parva is considered to be the most important pathogen in the region, we assessed the sensitivity of the RLB ..
  27. ncbi Theileria lestoquardi and T. annulata in cattle, sheep, and goats. In vitro and in vivo studies
    C G Brown
    Centre for Tropical Veterinary Medicine, University of Edinburgh, Midlothian, Scotland, UK
    Ann N Y Acad Sci 849:44-51. 1998
    b>Theileria annulata, causing bovine tropical theileriosis, and T. lestoquardi (syn T. hirci), the agent of malignant ovine theileriosis, are both transmitted by ticks of the genus Hyalomma...
  28. ncbi Survey of Theileria lestoquardi antibodies among Sudanese sheep
    D A Salih
    Central Veterinary Research Laboratories, P O Box 8067, Alamarat, Khartoum, Sudan
    Vet Parasitol 111:361-7. 2003
    The prevalence of Theileria lestoquardi antibodies in Sudanese sheep from nine geographical areas in Sudan was determined using indirect fluorescent antibody "IFA" test. Out of 315 samples examined, 51 (16...
  29. ncbi Diagnostic real-time PCR assay for the quantitative detection of Theileria equi from equine blood samples
    Chul Min Kim
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan
    Vet Parasitol 151:158-63. 2008
    We developed a TaqMan real-time polymerase chain reaction (PCR) assay for the quantitative detection of Theileria equi from the in vitro-cultured parasite and field blood samples collected from horses living in Ghana and Brazil...
  30. ncbi The Akt/PKB pathway is constitutively activated in Theileria-transformed leucocytes, but does not directly control constitutive NF-kappaB activation
    V T Heussler
    Molecular Pathology, Institute of Animal Pathology, University of Berne, CH-3012 Berne, Switzerland
    Cell Microbiol 3:537-50. 2001
    The intracellular protozoan parasites Theileria parva and Theileria annulata transform leucocytes by interfering with host cell signal transduction pathways...
  31. ncbi Sequence heterogeneity in the equi merozoite antigen gene (ema-1) of Theileria equi and development of an ema-1-specific TaqMan MGB assay for the detection of T. equi
    Raksha Bhoora
    Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, South Africa
    Vet Parasitol 172:33-45. 2010
    Although a quantitative real-time PCR assay (qPCR) assay for the detection of Theileria equi has been developed and evaluated, it is possible that additional, as yet undetected 18S rRNA gene sequence variants may exist...
  32. ncbi Molecular characterization of a Theileria lestoquardi gene encoding for immunogenic protein splice variants
    M A Bakheit
    Division of Veterinary Infectiology and Immunology, Research Center Borstel, Parkallee 22, 23845, Borstel, Germany
    Parasitol Res 100:161-70. 2006
    A Theileria lestoquardi schizont cDNA library was screened using sera collected from sheep recovering from a natural malignant theileriosis infection...
  33. ncbi Theileria: intracellular protozoan parasites of wild and domestic ruminants transmitted by ixodid ticks
    R Bishop
    The International Livestock Research Institute, P O Box 30709, Nairobi, Kenya
    Parasitology 129:S271-83. 2004
    b>Theileria are economically important, intra-cellular protozoa, transmitted by ixodid ticks, which infect wild and domestic ruminants. In the mammalian host, parasites infect leukocytes and erythrocytes...
  34. ncbi The phylogenetic position of the Theileria buffeli group in relation to other Theileria species
    Marc Jan Gubbels
    Division of Parasitology and Tropical Veterinary Medicine, Faculty of Veterinary Medicine, Utrecht University, The Netherlands
    Parasitol Res 88:S28-32. 2002
    b>Theileria parasites known as either T. buffeli, T. orientalis or T. sergenti share many characteristics and are referred to as the T. buffeli group...
  35. ncbi Phylogenetic analysis of Theileria species transmitted by Haemaphysalis qinghaiensis
    Hong Yin
    Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xujiaping 11, Lanzhou, 730046 Gansu, The People s Republic of China
    Parasitol Res 92:36-42. 2004
    The phylogenetic relationships between six isolates of Theileria spp. infective to small ruminants, and two isolates of Theileria spp...
  36. ncbi Identification of antigenic proteins of a Theileria species pathogenic for small ruminants in China recognized by antisera of infected animals
    Joana Miranda
    Instituto de Biologia Experimental e Tecnologica, Universidade Nova de Lisboa, Oeiras, Portugal
    Ann N Y Acad Sci 1026:161-4. 2004
    The antigenic proteins of the piroplasm stage of Theileria species (China), the causative agent of theilerosis of small ruminants in China, were analyzed by Western blot, revealing several specific immunoreactive proteins of different ..
  37. ncbi Development of a recombinant indirect ELISA for the diagnosis of Theileria sp. (China) infection in small ruminants
    J Miranda
    Instituto de Biologia Experimental e Tecnológica Instituto de Tecnologia Química e Biológica Universidade Nova de Lisboa, 2781 901, Oeiras, Portugal
    Parasitol Res 98:561-7. 2006
    b>Theileria sp. (China) causes severe limitations on the development of the livestock industry in the north-west of China...
  38. ncbi Detection and molecular characterization of Babesia caballi and Theileria equi isolates from endemic areas of Brazil
    Alexandra Heim
    Institute for Comparative Tropical Medicine and Parasitology, Ludwig Maximilian University Munich, Leopoldstr 5, 80802, Munich, Germany
    Parasitol Res 102:63-8. 2007
    ..was examined by the indirect fluorescent antibody test for detection of antibodies against Babesia caballi and Theileria equi...
  39. ncbi Evaluation of a PCR and comparison with RLB for detection and differentiation of Theileria sp. MK and other Theileria and Babesia species of small ruminants
    Kursat Altay
    Department of Parasitology, Faculty of Veterinary Medicine, University of Firat, 23119, Elazig, Turkey
    Parasitol Res 103:319-23. 2008
    b>Theileria sp. MK in sheep and goats were detected first time by polymerase chain reaction (PCR) and detection limit of PCR and reverse line blotting (RLB) were compared...
  40. ncbi Detection of Theileria and Babesia in brown brocket deer (Mazama gouazoubira) and marsh deer (Blastocerus dichotomus) in the State of Minas Gerais, Brazil
    Júlia A G da Silveira
    Departamento de Parasitologia, Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais, 31270 901, Belo Horizonte, MG, Brazil
    Vet Parasitol 177:61-6. 2011
    Intraerythrocytic protozoan species of the genera Theileria and Babesia are known to infect both wild and domestic animals, and both are transmitted by hard-ticks of the family Ixodidae...
  41. pmc Emergence of new types of Theileria orientalis in Australian cattle and possible cause of theileriosis outbreaks
    Joseph Kamau
    Department of Collaboration and Education, Research Center for Zoonosis Control, Graduate School of Veterinary Medicine, Hokkaido University, Japan
    Parasit Vectors 4:22. 2011
    b>Theileria parasites cause a benign infection of cattle in parts of Australia where they are endemic, but have, in recent years, been suspected of being responsible for a number of outbreaks of disease in cattle near the coast of New ..
  42. ncbi Genetic and biochemical analysis of erythrocyte-stage surface antigens belonging to a family of highly conserved proteins of Babesia equi and Theileria species
    D P Knowles
    Agricultural Research Service, US Department of Agriculture, Pullman, WA 99164 7030, USA
    Mol Biochem Parasitol 90:69-79. 1997
    ..by a single copy gene, and was previously shown to share 33% amino acid identity with similar sized proteins of Theileria sergenti and T. buffeli. A mean homology of 31% amino acid identity extends to similar sized proteins of T...
  43. ncbi Nucleotide sequence heterogeneity in the small subunit ribosomal RNA gene within Theileria equi from horses in Sudan
    Bashir Salim
    Department of Collaboration and Education, Research Center for Zoonosis Control, Hokkaido University, Sapporo 001 0020, Japan
    Parasitol Res 106:493-8. 2010
    This is a molecular epidemiological investigation on Theileria equi, a causative agent of equine piroplasmosis. Blood samples were collected from 127 horses from different geographical locations in Sudan...
  44. ncbi Equine babesiosis: seroprevalence, risk factors and comparison of different diagnostic methods in Jordan
    S M Abutarbush
    Department of Veterinary Clinical Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, Irbid, Jordan
    Transbound Emerg Dis 59:72-8. 2012
    ..Competitive enzyme-linked immunosorbent assay (cELISA) revealed 37 horses (14.6%) positive for Theileria equi, and none of the horses was positive for Babesia caballi...
  45. ncbi Molecular phylogenetic studies on Theileria spp. isolates (China) based on small subunit ribosomal RNA gene sequences
    Qin Liu
    State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Hubei Wuhan, 430070, People s Republic of China
    Trop Anim Health Prod 42:109-14. 2010
    Six Theileria spp. from cattle, buffalo and black goat were identified in the Hubei province of China. In order to study the taxonomic status of these parasites, phylogenetic analysis of 18S rRNA genes were carried out...
  46. ncbi The risks of translocating wildlife. Pathogenic infection with Theileria sp. and Elaeophora elaphi in an imported red deer
    U Hofle
    National Research Institute on Game Biology, Instituto de Investigacion en Recursos Cinegeticos IREC CSIC UCLM JCCM, P O Box 535, E 13 080 Ciudad Real, Spain
    Vet Parasitol 126:387-95. 2004
    ..Infection with Theileria sp. was detected in thin blood smears and confirmed by PCR and sequencing...
  47. pmc Re-emergence of the apicomplexan Theileria equi in the United States: elimination of persistent infection and transmission risk
    Massaro W Ueti
    Animal Diseases Research Unit, Agricultural Research Service, United States Department of Agriculture, Pullman, Washington, United States of America
    PLoS ONE 7:e44713. 2012
    ..The recent re-emergence of the apicomplexan Theileria equi in U.S. horses prompted testing whether imidocarb dipropionate was able to eliminate T...
  48. ncbi Failure of the Amblyomma cajennense nymph to become infected by Theileria equi after feeding on acute or chronically infected horses
    Múcio F B Ribeiro
    Departamento de Parasitologia, ICB UFMG, Belo Horizonte, Av Antonio Carlos, 6627 Belo Horizonte, Minas Gerais, Brazil
    Exp Parasitol 128:324-7. 2011
    Tick-borne diseases in horses are caused by the intraerythrocytic protozoan parasites Theileria equi and Babesia caballi. Although T...
  49. ncbi Hemoprotozoa of domestic animals in France: prevalence and molecular characterization
    A Criado-Fornelio
    Parasitology Laboratory, Department of Microbiology and Parasitology, Faculty of Pharmacy, University of Alcala, 28871 Alcala de Henares, Spain
    Vet Parasitol 159:73-6. 2009
    ..8% in sheep and 8.8% in cow). Theileria ovis was found in 1 sheep, Theileria sp. in 2 sheep, Theileria buffeli in 5 cows and B. major in 1 cow...
  50. ncbi A molecular phylogeny of the benign Theileria parasites based on major piroplasm surface protein (MPSP) gene sequences
    W Jeong
    Division of Veterinary Biotechnology, National Veterinary Research and Quarantine Service, 480, Anyang 6 dong, Anyang, Gyeonggido, 430 824 South Korea
    Parasitology 137:241-9. 2010
    To investigate the phylogeny of benign Theileria parasites, we determined the complete major piroplasm surface protein (MPSP) gene sequences for 6 benign theilerial organisms, including the first from tick...
  51. ncbi Molecular phylogenetic studies on Theileria parasites based on small subunit ribosomal RNA gene sequences
    K Chansiri
    Department of Biochemistry, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand
    Vet Parasitol 83:99-105. 1999
    Classification of Theileria parasites of south-east Asian countries is still ambiguous due to the lack of basic studies, especially their molecular genetic information...
  52. ncbi A molecular survey of bovine Theileria parasites among apparently healthy cattle and with a note on the distribution of ticks in eastern Turkey
    Munir Aktas
    Department of Parasitology, Faculty of Veterinary Medicine, University of Firat, 23119 Elazig, Turkey
    Vet Parasitol 138:179-85. 2006
    A survey of Theileria parasites in cattle in eastern Turkey was carried out using specific polymerase chain reaction. A total of 252 blood samples were collected from clinically healthy cattle between June and July 2004...
  53. pmc Theileria apicoplast as a target for chemotherapy
    Regina Lizundia
    Département Maladies Infectieuses, Laboratoire de Biologie Cellulaire Comparative des Apicomplexes, UMR 8104 CNRS U567 INSERM, Hôpital Cochin Bâtiment Gustave Roussy, Institut Cochin, Paris, France
    Antimicrob Agents Chemother 53:1213-7. 2009
    b>Theileria parasites cause severe bovine disease and death in a large part of the world. These apicomplexan parasites possess a relic plastid (apicoplast), whose metabolic pathways include several promising drug targets...
  54. ncbi Molecular detection of Theileria annae and Hepatozoon canis in foxes (Vulpes vulpes) in Croatia
    Danko Dezdek
    Croatian Veterinary Institute, Department for Pathology, Savska cesta 143, 10000 Zagreb, Croatia
    Vet Parasitol 172:333-6. 2010
    ..The investigation revealed four species of hematozoa in 57 foxes (30%), namely Theileria annae, Theileria sp. 3182/05 and Hepatozoon canis. T. annae was found in 10 foxes (5%), Theileria sp...
  55. ncbi Molecular evidence for transplacental transmission of Theileria equi from carrier mares to their apparently healthy foals
    M T E P Allsopp
    Onderstepoort Veterinary Institute, Private Bag X5, Onderstepoort 0110, South Africa
    Vet Parasitol 148:130-6. 2007
    The intra-erythrocytic parasite Theileria equi is one of two tick-transmitted causative agents of equine piroplasmosis. Piroplasms of T...
  56. ncbi Detection of Theileria ovis in naturally infected sheep by nested PCR
    Kursat Altay
    Department of Parasitology, Faculty of Veterinary Medicine, University of Firat, 23119 Elazig, Turkey
    Vet Parasitol 127:99-104. 2005
    A nested polymerase chain reaction (PCR) for the detection of Theileria ovis in sheep using oligonucleotide primers designed from the small subunit ribosomal RNA (SSU rRNA) gene sequence of T...
  57. ncbi Molecular identification of ovine Theileria species by a new PCR-RFLP method
    M Heidarpour Bami
    Clinical Science Department, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
    Vet Parasitol 161:171-7. 2009
    b>Theileria spp. infect wild and domestic ruminants in the tropical and subtropical regions of the world. Two species, T. lestoquardi and T. ovis, are suspected to cause ovine theileriosis in Iran...
  58. ncbi Epidemiological survey of Theileria orientalis infection in grazing cattle in the eastern part of Hokkaido, Japan
    Naomi Ota
    Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan
    J Vet Med Sci 71:937-44. 2009
    b>Theileria orientalis is one of the benign species of Theileria that is widely distributed in Japan and is sometimes responsible for serious economic losses in the livestock industry...
  59. ncbi [Roe deer (Capreolus capreolus) and red deer (Cervus elaphus) as a reservoir of protozoans from Babesia and Theileria genus in north-western Poland]
    Marek Sawczuk
    Katedra Genetyki, Uniwersytet Szczeciński
    Wiad Parazytol 51:243-7. 2005
    ..Majority of Theileria spp...
  60. ncbi Detection and differentiation of ovine Theileria and Babesia by reverse line blotting in China
    Qingli Niu
    State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, CAAS, Lanzhou, Gansu, China
    Parasitol Res 104:1417-23. 2009
    A reverse line blot (RLB) assay was developed for detection and specific identification of the different ovine Theileria and Babesia parasites...
  61. ncbi Identification of a piroplasm protein of Theileria orientalis that binds to bovine erythrocyte band 3
    Jung Yeon Kim
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan
    Mol Biochem Parasitol 137:193-200. 2004
    b>Theileria orientalis infects cattle and causes various disease symptoms, including anaemia and icterus...
  62. ncbi Molecular detection of Theileria and Babesia infections in cattle
    Kursat Altay
    Department of Parasitology, Faculty of Veterinary Medicine, University of Firat, 23119 Elazig, Turkey
    Vet Parasitol 158:295-301. 2008
    This study was carried out to determine the presence and distribution of tick-borne haemoprotozoan parasites (Theileria and Babesia) in apparently healthy cattle in the East Black Sea Region of Turkey...
  63. pmc Molecular diagnosis of Theileria and Babesia species infecting cattle in Northern Spain using reverse line blot macroarrays
    Josune García-Sanmartín
    Department of Animal Health, NEIKER Instituto Vasco de Investigación y Desarrollo Agrario, Berreaga 1, 48160 Derio, Bizkaia, Spain
    BMC Vet Res 2:16. 2006
    Piroplasmosis in cattle is caused by tick-borne haemoprotozoan parasites of the genera Theileria and Babesia...
  64. ncbi Molecular studies on Babesia, Theileria and Hepatozoon in southern Europe. Part II. Phylogenetic analysis and evolutionary history
    A Criado-Fornelio
    Microbiology and Parasitology Department, Faculty of Pharmacy, University of Alcala de Henares, 28871, Alcala de Henares, Spain
    Vet Parasitol 114:173-94. 2003
    Following a study on molecular epizootiology of Hepatozoon canis and piroplasmids (Babesia spp. and Theileria spp.) in southern Europe, newly obtained sequences of 18s rRNA gene were used for phylogenetic analysis...
  65. ncbi Survey of benign Theileria parasites of cattle and buffaloes in Thailand using allele-specific polymerase chain reaction of major piroplasm surface protein gene
    Nopporn Sarataphan
    Parasitology Section, National Institute of Animal Health, Kaset Klang, Chatuchak, Bangkok, Thailand
    J Vet Med Sci 65:133-5. 2003
    ..and analyzed by allele-specific PCR amplification of major piroplasm surface protein (MPSP) genes of benign Theileria parasites...
  66. ncbi Reverse line blot hybridization used to identify hemoprotozoa in Minorcan cattle
    Sonia Almeria
    Parasitology, Department of Animal Health, Veterinary School, Autonomous University of Barcelona, 08193 Bellaterra, Barcelona, Spain
    Ann N Y Acad Sci 969:78-82. 2002
    ..The oligonucleotides used were those for Theileria annulata, T. buffeli, T. taurotragi, T. velifera, Babesia bigemina, B. bovis, B. divergens, and B. major...
  67. ncbi Transmission of an unidentified Theileria species to small ruminants by Haemaphysalis qinghaiensis ticks collected in the field
    Hong Yin
    Department of Veterinary Medicine, Nanjing Agricultural University, Weigang, Jiangsu, People s Republic of China
    Parasitol Res 88:S25-7. 2002
    The transmission of a recently identified Theileria species pathogenic for sheep and goats in northern China is described...
  68. ncbi Reduction in tick numbers (Haemaphysalis longicornis), mortality and incidence of Theileria sergenti infection in field-grazed calves treated with flumethrin pour-on
    S Shimizu
    National Institute of Animal Health, 305 0856, Tsukuba, Japan
    Vet Parasitol 92:129-38. 2000
    ..Mortality due to Theileria sergenti infection also decreased significantly after more than 3 years of flumethrin pour-on application, ..
  69. pmc Babesia bicornis sp. nov. and Theileria bicornis sp. nov.: tick-borne parasites associated with mortality in the black rhinoceros (Diceros bicornis)
    Ard M Nijhof
    Division of Parasitology and Tropical Veterinary Medicine, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
    J Clin Microbiol 41:2249-54. 2003
    ..Screening of black rhinoceroses in South Africa revealed, in addition to B. bicornis, a second parasite, designated Theileria bicornis sp. nov.
  70. ncbi Theileria buffeli infection of a Michigan cow confirmed by small subunit ribosomal RNA gene analysis
    Raquel Cossio-Bayugar
    Department of Veterinary Pathobiology, The Texas Veterinary Medical Center, Texas A and M University, College Station, TX 77843 4467, USA
    Vet Parasitol 105:105-10. 2002
    b>Theileria buffeli, generally a benign parasite of cattle, has been reported in animals from Texas, Missouri and North Carolina. To date, there have been no reports of the parasite in cattle residing in northern portions of the US...
  71. ncbi The same but different: the biology of Theileria sporozoite entry into bovine cells
    M K Shaw
    Department of Biology, University of Pennsylvania, Philadelphia 19104 6018, USA
    Int J Parasitol 27:457-74. 1997
    b>Theileria are important tick-transmitted protozoan parasites that infect wild Bovidae and domestic animals throughout much of the world. Much of our understanding of Theileria sporozoite invasion of bovine cells is based on work on T...
  72. ncbi c-Myc activation by Theileria parasites promotes survival of infected B-lymphocytes
    Frederic Dessauge
    Laboratoire de Signalisation Immunoparasitaire, CNRS URA CNRS 2581, Departement de Parasitologie, Institut Pasteur, Batiment Elie Metchnikoff, 25 28 Rue du Dr Roux, 75724 Paris Cedex 15, France
    Oncogene 24:1075-83. 2005
    b>Theileria parasites infect and transform bovine lymphocytes, but host cell immortalization is reversible, as upon parasite death the lymphocytes rapidly die of apoptosis...
  73. ncbi Discrimination between Theileria lestoquardi and Theileria annulata in their vectors and hosts by RFLP based on the 18S rRNA gene
    Eva Spitalska
    School of Agriculture, Food and Rural Development, University of Newcastle, Newcastle upon Tyne, NE1 7RU, UK
    Parasitol Res 94:318-20. 2004
    b>Theileria lestoquardi and T. annulata can occur in similar vectors, and current available probes based on the 18S rRNA gene showed cross-reaction between the two species...
  74. ncbi Survey of Theileria parasite infection in cattle in Cambodia and Vietnam using piroplasm surface protein gene-specific polymerase chain reaction
    M Inoue
    Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan
    J Vet Med Sci 63:1155-7. 2001
    A survey of Theileria parasite infection in cattle in Cambodia and Vietnam was carried out by using allele-specific polymerase chain reaction...
  75. ncbi Phylogenetic analysis of Theileria and Babesia equi in relation to the establishment of parasite populations within novel host species and the development of diagnostic tests
    F Katzer
    Department of Veterinary Parasitology, University of Glasgow, UK
    Mol Biochem Parasitol 95:33-44. 1998
    ..In this paper we have carried out phylogenetic analyses of Theileria parasites isolated from different host species...
  76. ncbi Infectivity and cross-immunity studies of Theileria lestoquardi and Theileria annulata in sheep and cattle: I. In vivo responses
    I Leemans
    Department of Parasitology, Swedish University of Agricultural Sciences and National Veterinary Institute, Uppsala
    Vet Parasitol 82:179-92. 1999
    In a series of experiments, sporozoite stabilates of a Theileria lestoquardi (Lahr) and a T...
  77. ncbi Hijacking of host cell IKK signalosomes by the transforming parasite Theileria
    Volker T Heussler
    Division of Molecular Pathology, Institute of Animal Pathology, University of Bern, CH 3012 Bern, Switzerland
    Science 298:1033-6. 2002
    ..The intracellular protozoan parasite Theileria is the only eukaryote known to induce uncontrolled host cell proliferation...
  78. pmc Prevalence of Theileria sergenti infection in Korean native cattle by polymerase chain reaction
    Kun Ho Song
    Laboratory of Veterinary Internal Medicine, Chungnam National University, Daejeon 305 764, Republic of Korea
    Korean J Parasitol 41:141-5. 2003
    ..bulls) that had not received prior treatment or been vaccinated to prevent theileriosis were examined by PCR for Theileria sergenti infection from 2001 to 2002. In our study, the parasitemia range in T...
  79. ncbi Simultaneous differentiation between Theileria spp. and Babesia spp. on stained blood smear using PCR
    Parviz Shayan
    Pathobiology Group of Faculty of Vetrinary Medicine, University of Tehran, Tehran, Iran
    Parasitol Res 97:281-6. 2005
    ..The extracted DNA was subsequently amplified using specific primers derived from Theileria heat shock protein hsp70, Theileria lestoquardi ms1-2 gene, Babesia rhoptry protein gene and piroplasms hyper ..
  80. ncbi Simultaneous detection and differentiation of Theileria and Babesia parasites infecting small ruminants by reverse line blotting
    Leonhard Schnittger
    Department of Immunology and Cell Biology, Research Centre Borstel, Parkallee 22, 23845 Borstel, Germany
    Parasitol Res 92:189-96. 2004
    ..hypervariable region 4 (V4 region) of the small ribosomal RNA gene of ovine/caprine piroplasm species including Theileria lestoquardi, T. ovis, T. separata, Babesia ovis, B. motasi, B. crassa [comprising strains B. crassa (Iran) and B...
  81. ncbi Regulation of host cell survival by intracellular Plasmodium and Theileria parasites
    V Heussler
    Bernhard Nocht Institute for Tropical Medicine, Bernhard Nocht Str 74, 20359 Hamburg, Germany
    Parasitology 132:S49-60. 2006
    Plasmodium and Theileria parasites are obligate intracellular protozoa of the phylum Apicomplexa. Theileria infection of bovine leukocytes induces transformation of host cells and infected leukocytes can be kept indefinitely in culture...
  82. ncbi Cellular and molecular interactions between the apicomplexan parasites Plasmodium and Theileria and their host cells
    V T Heussler
    Bernhard Nocht Institute for Tropical Medicine, Bernhard Nocht Str 74, 20359 Hamburg, Germany
    Parasite 15:211-8. 2008
    Apicomplexan parasites of the genera Theileria and Plasmodium have complicated life cycles including infection of a vertebrate intermediate host and an arthropod definitive host...
  83. ncbi Passive transfer of Theileria equi antibodies to neonate foals of immune tolerant mares
    Sanjay Kumar
    National Research Centre on Equines, Hisar 125001, Haryana, India
    Vet Parasitol 151:80-5. 2008
    Equine babesiosis, a tick transmitted haemoprotozoan disease caused by Theileria equi is globally distributed and responsible for heavy economic losses to the equine husbandry...
  84. pmc Large-scale intron conservation and order-of-magnitude variation in intron loss/gain rates in apicomplexan evolution
    Scott William Roy
    Allan Wilson Centre for Molecular Ecology and Evolution, Massey University, Palmerston North, New Zealand
    Genome Res 16:1270-5. 2006
    ..6% of P. falciparum intron positions in conserved regions are shared with the distantly related apicomplexan Theileria parva, whereas only 18.2% of introns in the more intron-rich T. parva are shared with P. falciparum...
  85. ncbi Current status of vaccine development against Theileria parasites
    W I Morrison
    Division of Veterinary Clinical Sciences, Royal Dick School of Veterinary Studies, University of Edinburgh, Edinburgh, UK
    Parasitology 133:S169-87. 2006
    The tick-borne protozoan parasites Theileria parva and Theileria annulata cause economically important diseases of cattle in tropical and sub-tropical regions...
  86. ncbi Detection of a Theileria species in dogs in South Africa
    P T Matjila
    Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa
    Vet Parasitol 157:34-40. 2008
    A Theileria species was detected by PCR in blood samples collected from dogs in the Pietermaritzburg area and was also found in dogs presented at the Outpatients Clinic of the Onderstepoort Veterinary Academic Hospital (OVAH), in the ..
  87. ncbi The strategies of the Theileria parasite: a new twist in host-pathogen interactions
    Dirk A E Dobbelaere
    Division of Molecular Pathology, Institute of Animal Pathology, University of Bern, Langgassstrasse 122, CH 3012 Bern, Switzerland
    Curr Opin Immunol 16:524-30. 2004
    b>Theileria parasites infect and transform cells of the ruminant immune system. Continuous proliferation and survival of Theileria-transformed cells involves the well-orchestrated activation of several host-cell signalling pathways...
  88. ncbi Diversity of Babesia and Theileria species in symptomatic and asymptomatic dogs in Croatia
    Relja Beck
    Faculty of Veterinary Medicine, Department for Parasitology and Parasitic Diseases with Clinic, University of Zagreb, Heinzelova 55, Zagreb, Croatia
    Int J Parasitol 39:843-8. 2009
    ..number of "small" species of Babesia, some of which appear to be more closely related to members of the genus Theileria. In this work, blood samples were collected from 848 randomly selected, asymptomatic dogs and from 81 ..
  89. ncbi Progress towards understanding the immunobiology of Theileria parasites
    W Ivan Morrison
    The Roslin Institute, Royal Dick School of Veterinary Studies, University of Edinburgh, Edinburgh, UK
    Parasitology 136:1415-26. 2009
    The pathogenic Theileria species Theileria parva and T. annulata infect bovine leukocytes and erythrocytes causing acute, often fatal lymphoproliferative diseases in cattle...
  90. ncbi Phylogeny of sheep and goat Theileria and Babesia parasites
    Leonhard Schnittger
    Department of Immunology and Cell Biology, Research Center Borstel, Parkallee 22, 23845 Borstel, Germany
    Parasitol Res 91:398-406. 2003
    The phylogenetic relationship of Theileria and Babesia species infecting sheep and goats on the basis of their 18S RNA gene structure was addressed in the present study...
  91. ncbi Theileriosis in a Missouri beef herd caused by Theileria buffeli: case report, herd investigation, ultrastructure, phylogenetic analysis, and experimental transmission
    S L Stockham
    Veterinary Medical Diagnostic Laboratory, College of Veterinary Medicine, University of Missouri, Columbia 65211, USA
    Vet Pathol 37:11-21. 2000
    A 6-year-old Simmental cow infected with Theileria buffeli had a clinical disease characterized by theilerial parasitemia, macrocytic normochromic anemia with acanthocytosis and spherocytosis, lymphoid hyperplasia (lymphocytosis, ..
  92. ncbi Molecular and phylogenetic characterization of Theileria spp. parasites in autochthonous bovines (Mirandesa breed) in Portugal
    Clarisse Brígido
    Centro de Malaria e Outras Doencas Tropicais, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Rua da Junqueira, 96, 1349 008 Lisboa, Portugal
    Vet Parasitol 123:17-23. 2004
    ..chain reaction (PCR) analysis of the bovine blood revealed that 3 out of 116 animals were infected with Theileria and/or Babesia parasites, while reverse line blot hybridisation (RLB) analysis showed that these animals were ..
  93. ncbi Detection and identification of equine Theileria and Babesia species by reverse line blotting: epidemiological survey and phylogenetic analysis
    Daniel Nagore
    Department of Animal Health, Instituto Vasco de Investigación y Desarrollo Agrario NEIKER Berreaga 1, Derio, 48160 Bizkaia, Spain
    Vet Parasitol 123:41-54. 2004
    ..to develop a new and highly sensitive reverse line blot assay to detect and identify simultaneously different Theileria and Babesia species in horses...
  94. ncbi [Survey of T. annulata and T. buffeli/orientalis in cattle in the region of Erzincan using reverse line blotting]
    Kursat Altay
    Firat Universitesi, Veteriner Fakültesi Parazitoloji Anabilim Dali, Elazig, Turkey
    Turkiye Parazitol Derg 31:94-7. 2007
    This study was carried out to investigate Theileria annulata and T. buffeli/orientalis in cattle in the region of Erzincan using reverse line blotting (RLB) and microscopical examination...
  95. ncbi [Detection of Babesia caballi (Nuttall, 1910) and Theileria equi (Syn. Babesia equi , Laveran, 1901) by the polymerase chain reaction (PCR) in show and sport horses in the region of Ankara]
    H Zeynep Güçlü
    Ankara Universitesi Veteriner Fakültesi Parazitoloji Anabilim Dali, Ankara, Turkey
    Turkiye Parazitol Derg 31:89-93. 2007
    The aim of this study was to compare the diagnosis of Babesia caballi and Theileria equi by the polymerase chain reaction (PCR) and microscopic examination of blood specimens collected from show and sport horses in the region of Ankara ..
  96. ncbi Epidemiological studies on tick-borne diseases of cattle in Central Equatoria State, Southern Sudan
    D A Salih
    Central Veterinary Research Laboratories, Al Amarat, PO Box 8067, Khartoum, Sudan
    Parasitol Res 101:1035-44. 2007
    ..5%). Using reverse line blot, it was possible to detect and differentiate eight different piroplasms namely, Theileria parva (71.2%), Theileria mutans (73%), Theileria velifera (45.3%), Theileria taurotragi (2...
  97. ncbi Molecular identification, genetic diversity and distribution of Theileria and Babesia species infecting small ruminants
    Kursat Altay
    Department of Parasitology, Faculty of Veterinary Medicine, University of Firat, 23119 Elazig, Turkey
    Vet Parasitol 147:161-5. 2007
    Detection and identification of Theileria and Babesia species in 920 apparently healthy small ruminants in eastern Turkey, as well as parasite genetic diversity, was investigated using a specifically designed reverse line blot (RLB) ..
  98. ncbi Observed prevalence of tick-borne pathogens in domestic animals in Sicily, Italy during 2003-2005
    A Torina
    Instituto Zooprofilattico Sperimentale della Sicilia, Via G Marinuzzi no 3, 90129 Palermo, Sicily, Italy
    Zoonoses Public Health 54:8-15. 2007
    ..Pathogens analysed included Anaplasma, Ehrlichia, Rickettsia, Babesia and Theileria species, and Coxiella burnetii. The most prevalent TBP were Anaplasma and Babesia species...
  99. ncbi A serological study of Babesia caballi and Theileria equi in Thoroughbreds in Trinidad
    Zinora Asgarali
    Department of Paraclinical Sciences, School of Veterinary Medicine, Faculty of Medical Sciences, University of the West Indies, Trinidad, West Indies
    Vet Parasitol 144:167-71. 2007
    Ninety-three (93) horses were investigated for serum antibodies to Theileria equi (T. equi) and Babesia caballi (B. caballi) using the immunofluorescent antibody test (IFAT). Seventy-seven (82.8%) horses were seropositive; 31 (33...
  100. ncbi Hepatozoon canis infection in Slovakia: imported or autochthonous?
    Viktoria Majlathova
    Parasitological Institute SAS, Kosice, Slovakia
    Vector Borne Zoonotic Dis 7:199-202. 2007
    ..examined by PCR method using primers amplifying a fragment of the 18S rRNA spanning the V4 region of Babesia and Theileria. An unexpected determination of 450 bp DNA fragment of Hepatozoon canis was found in four samples...
  101. ncbi Serological diagnostic tools for the major tick-borne protozoan diseases of livestock
    M A Bakheit
    Parasitology Research Program, University of the Free State, Phuthaditjhaba, Republic of South Africa
    Parassitologia 49:53-62. 2007
    ..This paper reviews the pathogenic tick-borne protozoan diseases and the respective diagnostic ELISA based serological tests currently available for serosurveillance...

Research Grants13

  1. Ninth International Congress on Toxoplasmosis
    Boris Striepen; Fiscal Year: 2007
    ..of several important human and[unreadable] veterinary parasites including Plasmodium (malaria), Babesia, Theileria,[unreadable] Cryptosporidium (appendix B pathogen), Cyclospora, Neospora, Eimeria, and Isospora...
  2. EXTRACELLULAR DEVELOPMENT IN VITRO OF MALARIA PARASITES
    William Trager; Fiscal Year: 1991
    ..for serious congenital infection and recently of increased significance in AIDS patients, the cattle parasite Theileria parva, cause of East Coast fever and, most important, the malarial parasites...
  3. RP FALCIPARUM DHFR IN DRUG SCREENING
    CAROL SIBLEY; Fiscal Year: 1999
    ..the related human parasites, Toxoplasma, Pneumocystis, Cryptosporidium or the agricultural parasites, Eimeria, Theileria or Babesia...
  4. SERINE PROTEINASES IN APICOMPLEXAN PARASITES
    Kami Kim; Fiscal Year: 2009
    ..In addition to illuminating the function and biology of T. gondii secretory organelles, these studies will determine whether subtilases are a viable chemotherapeutic target for treatment of human infections with Apicomplexan parasites. ..
  5. Differentiation and Signaling in Toxoplasmosis
    Kami Kim; Fiscal Year: 2008
    ..These studies will further elucidate cAMP signaling pathways in T. gondii and determine the role of cAMP signaling pathways during T. gondii differentiation into latent bradyzoites. ..
  6. Proteomic analysis of the T. gondii vacuolar membrane
    Anthony Sinai; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  7. Blockade of host apoptosis by Toxoplasma gondii
    Anthony P Sinai; Fiscal Year: 2010
    ..Dissection of these pathways is particularly important given the targets of NFKB many of the cytokines implicated both in the pathogenesis of acute toxoplasmosis and the development of immunity to the parasite. ..
  8. Comparison of US and European Babesia divergens Isolates
    Patricia Holman; Fiscal Year: 2004
    ..The molecular aspects may provide information that will be useful in future efforts to devise diagnostic tests. ..
  9. 7th International Congress on Toxoplasmosis
    Kami Kim; Fiscal Year: 2003
    ..include most of the major protozoan pathogens of humans and animals, such as Plasmodia (malaria), Babesia, Theileria, Cryptosporidia, Cyclospora, Neospora, Eimeria, and Isospora...
  10. Purine salvage as a chemotherapeutic target in malaria
    Kami Kim; Fiscal Year: 2002
    ..Inhibitors designed in the Schramm and Grubmeyer laboratories will be tested against P. falciparum cultured in human erythrocytes and in mice infected with P. yoelii, a lethal form of mouse malaria. ..
  11. TOXOPLASMA DEVELOPMENT AND CELL CYCLE
    Kami Kim; Fiscal Year: 2002
    ..These will be the initial experiments in a long-term effort to define the role of cell cycle regulation in Toxoplasma tachyzoite-bradyzoite differentiation and virulence. ..
  12. EIAV Control by DNA Vaccine-Induced CTL
    ROBERT MEALEY; Fiscal Year: 2006
    ..The information obtained from the proposed studies should have implications for HIV-1 vaccine design, where experiments of this type may be more difficult. [unreadable] [unreadable]..
  13. EIAV Control by High Avidity Rev-Specific CTL Clones
    ROBERT MEALEY; Fiscal Year: 2005
    ..The information obtained from the proposed studies should have implications for HIV-1 immunotherapy and vaccine design, where experiments of this type may be more difficult. ..