microsporum

Summary

Summary: A mitosporic Oxygenales fungal genus causing various diseases of the skin and hair. The species Microsporum canis produces TINEA CAPITIS and tinea corporis, which usually are acquired from domestic cats and dogs. Teleomorphs includes Arthroderma (Nannizzia). (Alexopoulos et al., Introductory Mycology, 4th edition, p305)

Top Publications

  1. ncbi A study of dermatophytes and their in-vitro antifungal sensitivity
    M N Sumana
    Department of Microbiology, Govt Medical College, Mysore
    Indian J Pathol Microbiol 45:169-72. 2002
  2. pmc Use of the sensititre colorimetric microdilution panel for antifungal susceptibility testing of dermatophytes
    I Pujol
    Laboratori de Microbiologia, Hospital Universitari de Sant Joan de Reus Unitat de Microbiologia, Facultat de Medicina Institut d Estudis Avançats, Universitat Rovira i Virgili, Reus, Tarragona, Spain
    J Clin Microbiol 40:2618-21. 2002
  3. ncbi Anti dermatophytic activity of Azardirachta indica (neem) by invitro study
    V Natarajan
    Departments of Microbiology and Dermatology, Rajah Muthiah Medical College, Annamalai University, Annamalai Nagar, Tamil Nadu
    Indian J Pathol Microbiol 45:311-3. 2002
  4. ncbi Dermatophytoses in cats and humans in central Italy: epidemiological aspects
    R Iorio
    Dipartimento di Scienze Biomediche Comparate, Università di Teramo, Teramo, Italy
    Mycoses 50:491-5. 2007
  5. pmc Phylogenetic classification and species identification of dermatophyte strains based on DNA sequences of nuclear ribosomal internal transcribed spacer 1 regions
    K Makimura
    Teikyo University Institute of Medical Mycology, Tokyo, Japan
    J Clin Microbiol 37:920-4. 1999
  6. ncbi Antifungal effect of eugenol and nerolidol against Microsporum gypseum in a guinea pig model
    Sook Jin Lee
    Laboratory of Veterinary Clinical Pathology, College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea
    Biol Pharm Bull 30:184-8. 2007
  7. ncbi Microsporum canis tinea capitis in an 8-month-old infant successfully treated with 2 weekly pulses of oral itraconazole
    E Koumantaki
    Department of Dermatology, A. Syggros Hospital, Athens, Greece
    Pediatr Dermatol 18:60-2. 2001
  8. ncbi Tinea faciei in an infant caused by Microsporum gypseum simulating a dry impetigo
    Paulo Ricardo Criado
    Dermatology Unit, Hospital do Servidor Publico Estadual de Sao Paulo, Brazil
    Pediatr Dermatol 22:536-8. 2005
  9. ncbi Purification of diacylglycerol kinase from Microsporum gypseum and its phosphorylation by the catalytic subunit of protein kinase A
    E Haq
    Department of Biochemistry, Postgraduate Institute of Medical Education and Research, Chandigarh-160 012, India
    Arch Biochem Biophys 392:219-25. 2001
  10. ncbi Kerion Celsi in a newborn due to Microsporum canis
    Nicola Aste
    Department of Dermatology, University of Cagliari, Cagliari, Italy
    Mycoses 47:236-7. 2004

Research Grants

  1. MECHANISM OF IL-12 INHIBITION BY CANDIDA ALBICANS
    Mahmoud Ghannoum; Fiscal Year: 2009
  2. Biology and Drug Resistance of Candida Biofilms
    Mahmoud Ghannoum; Fiscal Year: 2005

Detail Information

Publications219 found, 100 shown here

  1. ncbi A study of dermatophytes and their in-vitro antifungal sensitivity
    M N Sumana
    Department of Microbiology, Govt Medical College, Mysore
    Indian J Pathol Microbiol 45:169-72. 2002
    ..55%) were Trichophyton mentagrophytes and 4 (11.1%) were Trichophyton violaceum. One isolate each of Microsporum gypseum & Epidermophyton floccosum were obtained...
  2. pmc Use of the sensititre colorimetric microdilution panel for antifungal susceptibility testing of dermatophytes
    I Pujol
    Laboratori de Microbiologia, Hospital Universitari de Sant Joan de Reus Unitat de Microbiologia, Facultat de Medicina Institut d Estudis Avançats, Universitat Rovira i Virgili, Reus, Tarragona, Spain
    J Clin Microbiol 40:2618-21. 2002
    ..YeastOne antifungal panel was used to test 49 dermatophytes belonging to the species Epidermophyton floccosum, Microsporum gypseum, Microsporum canis, Trichophyton tonsurans, Trichophyton rubrum, and Trichophyton mentagrophytes...
  3. ncbi Anti dermatophytic activity of Azardirachta indica (neem) by invitro study
    V Natarajan
    Departments of Microbiology and Dermatology, Rajah Muthiah Medical College, Annamalai University, Annamalai Nagar, Tamil Nadu
    Indian J Pathol Microbiol 45:311-3. 2002
    ..against dermatophytes such as Trichophyton ruberum, Trichophyton, Mentagrophytes, Trichophyton violaceum, Microsporum nanum and Epidermophyton floccosum by tube dilution technique...
  4. ncbi Dermatophytoses in cats and humans in central Italy: epidemiological aspects
    R Iorio
    Dipartimento di Scienze Biomediche Comparate, Università di Teramo, Teramo, Italy
    Mycoses 50:491-5. 2007
    ..b>Microsporum canis was the most common dermatophyte isolated in both cat groups while Trichophyton mentagrophytes was the ..
  5. pmc Phylogenetic classification and species identification of dermatophyte strains based on DNA sequences of nuclear ribosomal internal transcribed spacer 1 regions
    K Makimura
    Teikyo University Institute of Medical Mycology, Tokyo, Japan
    J Clin Microbiol 37:920-4. 1999
    The mutual phylogenetic relationships of dermatophytes of the genera Trichophyton, Microsporum, and Epidermophyton were demonstrated by using internal transcribed spacer 1 (ITS1) region ribosomal DNA sequences. Trichophyton spp...
  6. ncbi Antifungal effect of eugenol and nerolidol against Microsporum gypseum in a guinea pig model
    Sook Jin Lee
    Laboratory of Veterinary Clinical Pathology, College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea
    Biol Pharm Bull 30:184-8. 2007
    ..activities of eugenol and nerolidol isolated from Japanese cypress oil in a guinea pig model infected by Microsporum gypseum (M. gypseum)...
  7. ncbi Microsporum canis tinea capitis in an 8-month-old infant successfully treated with 2 weekly pulses of oral itraconazole
    E Koumantaki
    Department of Dermatology, A. Syggros Hospital, Athens, Greece
    Pediatr Dermatol 18:60-2. 2001
    We report an 8-month-old girl with tinea capitis caused by Microsporum canis which was successfully treated with two pulses of oral itraconazole 50 mg/day, each of 1 week duration with an interval of 2 weeks. M...
  8. ncbi Tinea faciei in an infant caused by Microsporum gypseum simulating a dry impetigo
    Paulo Ricardo Criado
    Dermatology Unit, Hospital do Servidor Publico Estadual de Sao Paulo, Brazil
    Pediatr Dermatol 22:536-8. 2005
    ..The initial examination led us to the clinical diagnosis of impetigo. The mycologic studies found an uncommon dermatophyte agent, Microsporum gypseum. The main differential diagnosis of tinea faciei is discussed.
  9. ncbi Purification of diacylglycerol kinase from Microsporum gypseum and its phosphorylation by the catalytic subunit of protein kinase A
    E Haq
    Department of Biochemistry, Postgraduate Institute of Medical Education and Research, Chandigarh-160 012, India
    Arch Biochem Biophys 392:219-25. 2001
    Diacylglycerol (DG) kinase (EC 2.7.1.107) was purified to homogeneity from the soluble extract of Microsporum gypseum, a dermatophyte...
  10. ncbi Kerion Celsi in a newborn due to Microsporum canis
    Nicola Aste
    Department of Dermatology, University of Cagliari, Cagliari, Italy
    Mycoses 47:236-7. 2004
    The present study deals with a case of a 40-day-old girl with kerion Celsi caused by Microsporum canis. The source of the infection were the parents who presented tinea corporis caused by M. canis...
  11. ncbi Identification of novel secreted proteases during extracellular proteolysis by dermatophytes at acidic pH
    Dev Sriranganadane
    Department of Dermatology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Proteomics 11:4422-33. 2011
    ..The validation of such genome predictions instigated the present study on two dermatophyte species, Microsporum canis and Arthroderma benhamiae...
  12. ncbi Internal Transcribed Spacer (ITS) of rDNA of appendaged and non-appendaged strains of Microsporum gypseum reveals Microsporum appendiculatum as its synonym
    Rahul Sharma
    Mycological Research Laboratory, Department of Biological Sciences, Rani Durgavati University, Jabalpur 482001, MP, India
    Antonie Van Leeuwenhoek 89:197-202. 2006
    Recently a new taxon of geophilic dermatophytes was established as Microsporum appendiculatum Bhat and Mariam, based on the presence of appendaged macroconidia...
  13. pmc In vitro profiling of pramiconazole and in vivo evaluation in Microsporum canis dermatitis and Candida albicans vaginitis laboratory models
    Kelly de Wit
    Laboratory of Microbiology, Parasitology and Hygiene, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, Antwerp University, Groenenborgerlaan 171, Antwerp, Belgium
    Antimicrob Agents Chemother 54:4927-9. 2010
    ..50% inhibitory concentration [IC₅₀], 0.04 to 1.83 μM) and Microsporum and Trichophyton spp. (IC₅₀, 0.15 to 1...
  14. ncbi Humoral and cellular immune response to a crude exo-antigen and purified keratinase of Microsporum canis in experimentally infected guinea pigs
    B R Mignon
    Faculty of Veterinary Medicine, Department of Parasitology and Parasitic Diseases, University of Liege, Liege, Belgium
    Med Mycol 37:123-9. 1999
    In order to understand better the host-parasite relationship and to compare with previous observations in Microsporum canis naturally infected cats, the humoral and cellular immune responses to both a crude exo-antigen and a 31...
  15. ncbi RNA silencing in the dermatophyte Microsporum canis
    Sandy Vermout
    Department of Infectious and Parasitic Diseases, Parasitology, Faculty of Veterinary Medicine, University of Liege, Liege, Belgium
    FEMS Microbiol Lett 275:38-45. 2007
    Dermatomycoses caused by Microsporum canis are frequent in domestic animals and easily transmissible to humans...
  16. ncbi Reconstructed interfollicular feline epidermis as a model for Microsporum canis dermatophytosis
    Jeremy Tabart
    Department of Parasitology and Parasitic Diseases, Faculty of Veterinary Medicine, University of Liege, B43 Sart Tilman, 4000 Liege, Belgium
    J Med Microbiol 56:971-5. 2007
    b>Microsporum canis is a pathogenic fungus that causes a superficial cutaneous infection called dermatophytosis...
  17. ncbi The in vitro and in vivo production of a 31.5-kD keratinolytic subtilase from Microsporum canis and the clinical status in naturally infected cats
    B R Mignon
    Department of Parasitology, Faculty of Veterinary Medicine, University of Liege, Belgium
    Dermatology 196:438-41. 1998
    b>Microsporum-canis-infected cats, especially the asymptomatic infected ones, are mainly responsible for the zoonotic disease. The important variability of the clinical signs in cats is poorly understood. Recently, a 31...
  18. ncbi Production of extracellular enzymes by Microsporum canis and their role in its virulence
    F C Viani
    Departamento de Microbiologia, ICB-USP, , Brazil
    Med Mycol 39:463-8. 2001
    b>Microsporum canis is the most prevalent dermatophyte of domestic animals. Several enzymes produced by dermatophytes, particularly keratinases, are considered to play a role in the virulence of this fungus...
  19. ncbi A virulent genotype of Microsporum canis is responsible for the majority of human infections
    Rahul Sharma
    Institute of Microbiology and Hygiene Charité, Humboldt University, Dorotheenstr 96, D 10117, Berlin, Germany
    J Med Microbiol 56:1377-85. 2007
    The zoophilic dermatophyte species Microsporum canis belongs to the Arthroderma otae complex and is known to mate with tester strains of that teleomorph species, at least in the laboratory...
  20. pmc Secreted metalloprotease gene family of Microsporum canis
    Frédéric Brouta
    Department of Parasitology and Parasitic Diseases, Faculty of Veterinary Medicine, University of Liege, Liege, Belgium
    Infect Immun 70:5676-83. 2002
    Keratinolytic proteases secreted by dermatophytes are likely to be virulence-related factors. Microsporum canis, the main agent of dermatophytosis in dogs and cats, causes a zoonosis that is frequently reported...
  21. ncbi Inhibitory effect of the plant Boerhavia diffusa l. against the dermatophytic fungus Microsporum fulvum
    Anurag Agrawal
    Department of Chemistry, Faculty of Science, Dayalbagh Educational Institute, Dayalbagh, Agra 282 005, India
    J Environ Biol 25:307-11. 2004
    ..aqueous) of aerial and root parts of Boerhavia diffusa (Nictaginaceae) was screened against dermatophytic fungi Microsporum fulvum...
  22. ncbi Multilocus differentiation of the related dermatophytes Microsporum canis, Microsporum ferrugineum and Microsporum audouinii
    Ali Rezaei-Matehkolaei
    Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
    J Med Microbiol 61:57-63. 2012
    b>Microsporum ferrugineum, an uncommon causative agent of dermatophytosis, has restricted endemicity. Iranian strains suspected to be M...
  23. ncbi Microsporum gypseum infection in the Siena area in 2005-2006
    C Romano
    Department of Clinical Medicine and Immunological Sciences, Dermatology Section, Siena University, Siena, Italy
    Mycoses 52:67-71. 2009
    Fourteen cases of dermatophytosis caused by Microsporum gypseum, representing 6.8% of all dermatophytic infections reported, were diagnosed in Siena, Italy, between 2005 and 2006...
  24. ncbi Inter-single-sequence-repeat-PCR typing as a new tool for identification of Microsporum canis strains
    Jose Cano
    Department de Ciencies Mediques Basiques, Universitat Rovira i Virgili, Unitat de Microbiologia, Facultat de Medicina i Ciencies de la Salut, Carrer Sant Llorenc 21, Reus, 43201 Tarragona, Spain
    J Dermatol Sci 39:17-21. 2005
    b>Microsporum canis is a ubiquitous dermatophyte that commonly causes human infections. Since contact with infected animals is the usual way of infection, tracing its source is an essential preventive measure.
  25. ncbi Antifungal and marker effects of Talisia esculenta lectin on Microsporum canis in vitro
    A Q Pinheiro
    Veterinary Faculty, State University of Ceara, Fortaleza CE, Brazil
    J Appl Microbiol 107:2063-9. 2009
    ..the usefulness of lectin obtained from Talisia esculenta (TEL) seeds as a tool to recognize and study Microsporum canis...
  26. pmc Organization and evolutionary trajectory of the mating type (MAT) locus in dermatophyte and dimorphic fungal pathogens
    Wenjun Li
    Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Eukaryot Cell 9:46-58. 2010
    ..We identified the MAT locus of five dermatophyte fungal pathogens (Microsporum gypseum, Microsporum canis, Trichophyton equinum, Trichophyton rubrum, and Trichophyton tonsurans) and a ..
  27. ncbi Disseminated dermatophytosis caused by Microsporum gypseum in an AIDS patient: response to terbinafine and amorolfine
    M C G Galhardo
    Evandro Chagas Clinical Research Institute Oswaldo Cruz Foundation Fiocruz, Rio de Janeiro, Brazil
    Mycoses 47:238-41. 2004
    ..The diagnosis of dermatophytosis was based on the isolation of Microsporum gypseum from scales scraped from the skin lesions...
  28. ncbi Isolation, characterization, and disruption of dnr1, the areA/nit-2-like nitrogen regulatory gene of the zoophilic dermatophyte, Microsporum canis
    Tsuyoshi Yamada
    Teikyo University Institute of Medical Mycology, Hachioji, Tokyo, Japan
    Med Mycol 44:243-52. 2006
    ..areA from Aspergillus nidulans and nit-2 from Neurospora crassa was isolated from the zoophilic dermatophyte, Microsporum canis...
  29. ncbi High rate of Microsporum canis feline and canine dermatophytoses in Northeast Brazil: epidemiological and diagnostic features
    R S N Brilhante
    School of Veterinary Medicine, Post Graduation Program in Veterinary Science, State University of Ceara, Fortaleza CE, Brazil
    Mycopathologia 156:303-8. 2003
    ..3%) canine specimens and 14 of the 38 (36.8%) feline specimens. The identified dermatophytes were Microsporum canis (95%), M. gypseum (2.5%) and Trichophyton mentagrophytes var. mentagrophytes (2.5%)...
  30. ncbi Secreted subtilisin Sub3 from Microsporum canis is required for adherence to but not for invasion of the epidermis
    A Baldo
    Department of Parasitology and Parasitic Diseases, University of Liege, B43 Sart Tilman, 4000 Liege, Belgium
    Br J Dermatol 162:990-7. 2010
    b>Microsporum canis is a pathogenic dermatophyte that causes a superficial cutaneous mycosis, mainly in cats and humans...
  31. ncbi Lack of efficacy of 6-week treatment with oral terbinafine for tinea capitis due to Microsporum canis in children
    V Dragos
    University Medical Centre Ljubljana, Department of Dermatology, Slovenia
    Pediatr Dermatol 14:46-8. 1997
    Twenty-two children aged 2 to 9 years with noninflammatory tinea capitis due to Microsporum canis were evaluated in an open clinical pilot study run from January 1994 to July 1995...
  32. ncbi Purification and characterization of a 315 kDa keratinolytic subtilisin-like serine protease from Microsporum canis and evidence of its secretion in naturally infected cats
    B Mignon
    Department of Parasitology and Parasitic Diseases, Faculty of Veterinary Medicine, University of Liege, Belgium
    Med Mycol 36:395-404. 1998
    A keratinolytic protease, secreted as the major component by a feline clinical isolate of Microsporum canis cultivated in a minimal medium containing cat keratin, was purified by affinity chromatography on bacitracin agarose and gel ..
  33. ncbi Evaluation of fungicidal efficacy of benzalkonium chloride (Steramina G u.v.) and Virkon-S against Microsporum canis for environmental disinfection
    V Marchetti
    Department of Veterinary Clinics, University of Pisa, Via Livornese, 56010, San Piero a Grado, Pisa, Italy
    Vet Res Commun 30:255-61. 2006
    ..chloride; Formenti Grünenthal) and Virkon-S (multipurpose system; Antec International) against Microsporum canis-infected hairs and spores...
  34. ncbi Species-identification of dermatophytes Trichophyton, Microsporum and Epidermophyton by PCR and PCR-RFLP targeting of the DNA topoisomerase II genes
    Toshio Kanbe
    Division of Molecular Mycology and Medicine, Department of Advanced Medical Science, Center for Neural Disease and Cancer, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa Ku, Nagoya 466 8550, Japan
    J Dermatol Sci 33:41-54. 2003
    ..We have focused on the DNA topoisomerase II genes of pathogenic fungi and have previously applied polymerase chain reaction (PCR)-based identification of several species including the some of the major dermatophyte species...
  35. ncbi Terbinafine: efficacy and tolerability in young children with tinea capitis due to Microsporum canis
    H Silm
    Department of Dermatology and Venereology, Tartu University, Lossi 21 23, 51003 Tartu, Estonia
    J Eur Acad Dermatol Venereol 16:228-30. 2002
    We carried out an open, prospective, uncontrolled study to evaluate the efficacy and tolerability of terbinafine in the treatment of young children with tinea capitis due to Microsporum canis.
  36. ncbi Tinea capitis caused by Microsporum canis treated with terbinafine
    Nicola Aste
    Department of Dermatology, University of Cagliari, Cagliari, Italy
    Mycoses 47:428-30. 2004
    ..Numerous dermatophytes of the genus Microsporum and Tricophyton can cause tinea capitis and griseofulvin is still today the treatment of choice...
  37. ncbi Molecular taxonomy of dermatophytes and related fungi by chitin synthase 1 (CHS1) gene sequences
    Asuka Hirai
    Department of Pathobiology, Nihon University School of Veterinary Medicine, 1866, Kameino, Fujisawa, Kanagawa 252 8510, Japan
    Antonie Van Leeuwenhoek 83:11-20. 2003
    ..sequences of the CHS1 gene from dermatophytes and related fungi in the genera Chrysosporium, Epidermophyton, Microsporum and Trichophyton were investigated using molecular methods...
  38. ncbi A randomized, double-blind, parallel-group, duration-finding study of oral terbinafine and open-label, high-dose griseofulvin in children with tinea capitis due to Microsporum species
    J Lipozencic
    Department of Dermatology and Venereology, University Hospital Center, Zagreb, Croatia
    Br J Dermatol 146:816-23. 2002
    ..However, the optimal treatment duration for its use in the treatment of tinea capitis caused by Microsporum species has not yet been determined.
  39. ncbi Treatment of Microsporum spp. tinea capitis with pulsed oral terbinafine
    R Ungpakorn
    Institute of Dermatology, Bangkok, Thailand
    Clin Exp Dermatol 29:300-3. 2004
    ..It is also useful in treating tinea capitis, although for Microsporum canis and some ectothrix organisms, the effectiveness of the drug may be less than for some endothrix ..
  40. ncbi Antifungal activities of pelargonic and capric acid on Microsporum gypseum
    M Chadeganipour
    Mycology and Parasitology Department, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
    Mycoses 44:109-12. 2001
    The inhibitory effects of pelargonic and capric acid on Microsporum gypseum were examined...
  41. ncbi Secreted dipeptidyl peptidases as potential virulence factors for Microsporum canis
    Sandy Vermout
    Department of Infectious and Parasitic Diseases, Parasitology, Faculty of Veterinary Medicine, University of Liege, Liege, Belgium
    FEMS Immunol Med Microbiol 54:299-308. 2008
    Dermatophytoses caused by Microsporum canis are frequently encountered in cats and dogs; they are highly contagious and readily transmissible to humans...
  42. ncbi Purification and characterization of a 43.5 kDa keratinolytic metalloprotease from Microsporum canis
    F Brouta
    Department of Parasitology and Parasitic Diseases, Faculty of Veterinary Medicine, , Belgium
    Med Mycol 39:269-75. 2001
    A keratinolytic protease secreted by a feline clinical isolate of Microsporum canis cultivated in a broth containing feline keratin as the sole nitrogen source was purified from the culture filtrate by affinity chromatography on ..
  43. ncbi Phylogenetic relation of Epidermophyton floccosum to the species of Microsporum and Trichophyton in chitin synthase 1 (CHS1) gene sequences
    R Kano
    Department of Pathobiology, Nihon University School of Veterinary Medicine, Kanagawa, Japan
    Mycopathologia 146:111-3. 1999
    ..was analyzed to determine its phylogenetic relation to eight other dermatophyte species belonging to the genera Microsporum and Trichophyton, which were sequenced in our previous studies...
  44. ncbi Secreted subtilisins of Microsporum canis are involved in adherence of arthroconidia to feline corneocytes
    Aline Baldo
    Department of Parasitology and Parasitic Diseases, Faculty of Veterinary Medicine, University of Liege, B43 Sart Tilman, 4000 Liege, Belgium
    J Med Microbiol 57:1152-6. 2008
    b>Microsporum canis is a pathogenic fungus that causes a superficial cutaneous infection called dermatophytosis, mainly in cats and humans. The mechanisms involved in adherence of M. canis to epidermis have never been investigated...
  45. pmc Specific primers for rapid detection of Microsporum audouinii by PCR in clinical samples
    H D Roque
    Lab Micologia, Instituto de Higiene e Medicina Tropical CREM, Universidade Nova de Lisboa, Portugal
    J Clin Microbiol 44:4336-41. 2006
    ..The initial PCR analysis rendered a specific DNA fragment for Microsporum audouinii, which was cloned and sequenced...
  46. ncbi Doubled dose of oral terbinafine is required for Microsporum canis tinea capitis
    E Koumantaki
    Skin Department, Athens University, A. Syngros Hospital, Athens, Greece
    Pediatr Dermatol 18:339-42. 2001
    Fourteen children, ages 1-15 years, with Microsporum canis tinea capitis were given oral terbinafine for 4 weeks at the recommended daily dose according to their weight: 10-20 kg, 62.5 mg; 20-40 kg, 125 mg; > 40 kg, 250 mg...
  47. ncbi Isolation of a Microsporum canis gene family encoding three subtilisin-like proteases expressed in vivo
    Frédéric Descamps
    Department of Parasitology and Parasitic Diseases, Faculty of Veterinary Medicine, University of Liege, Belgium
    J Invest Dermatol 119:830-5. 2002
    b>Microsporum canis is the main agent of dermatophytosis in dogs and cats and is responsible for frequent zoonosis. The pathogenesis of the disease remains largely unknown, however...
  48. ncbi Itraconazole in the treatment of tinea capitis caused by Microsporum canis: experience in a large cohort
    Gabriele Ginter-Hanselmayer
    Department of Dermatology, University of Graz, Graz, Austria
    Pediatr Dermatol 21:499-502. 2004
    Mycotic scalp infection caused by Microsporum canis is one of the more recalcitrant disorders, with increasing incidence during the last decade...
  49. ncbi Isolation of a promoter region of a secreted metalloprotease gene from Microsporum canis
    Tsuyoshi Yamada
    Teikyo University Institute of Medical Mycology, Tokyo 192 0395, Japan
    Jpn J Infect Dis 57:25-8. 2004
    MEP3 of Microsporum canis encodes a 43.5 kDa extracellular keratinolytic metalloprotease, which is thought to be one of the virulence-related factors in dermatophytosis...
  50. ncbi Multiplication of an ancestral gene encoding secreted fungalysin preceded species differentiation in the dermatophytes Trichophyton and Microsporum
    Olivier Jousson
    Dermatology Service DHURDV, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Microbiology 150:301-10. 2004
    ..source a substantial proteolytic activity was secreted by Trichophyton rubrum, Trichophyton mentagrophytes and Microsporum canis...
  51. ncbi Dermatophytes growth curve and in vitro susceptibility test: a broth micro-titration method
    A B Alió
    Dermatology Department and Mycology Laboratory, Instituto de Biomedicina, Universidad Central de Venezuela, Caracas, Venezuela
    Med Mycol 43:319-25. 2005
    ..We assayed an in vitro susceptibility test with 40 isolates of dermatophytes: Microsporum canis, Trichophyton rubrum, Trichophyton mentagrophytes and Epidermophyton floccosum against griseofulvin, ..
  52. ncbi Dermatophyte infections in the Ljubljana region, Slovenia, 1995-2002
    Mateja Dolenc-Voljc
    Department of Dermatovenereology, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia
    Mycoses 48:181-6. 2005
    ..Dermatophytes were identified in 8286 (71.2%) positive cultures. Microsporum canis was the most frequent dermatophyte isolated (46.8%), followed by Trichophyton rubrum (36.7%), T...
  53. ncbi Tinea capitis: a treatment update
    Brandie J Roberts
    Children s Hospital and Health Center and University of California San Diego Medical Center, San Diego, CA, USA
    Pediatr Ann 34:191-200. 2005
    ....
  54. ncbi Comparison of disk diffusion method and broth microdilution method for antifungal susceptibility testing of dermatophytes
    A Esteban
    Departament de Sanitat i d Anatomia Animals Microbiologia, Facultat de Veterinaria, Universitat Autonoma de Barcelona, Barcelona, Spain
    Med Mycol 43:61-6. 2005
    ..method to determine antifungal susceptibility of 59 isolates of dermatophytes, namely Epidermophyton floccosum, Microsporum canis, M. gypseum, Trichophyton mentagrophytes, T. rubrum and T...
  55. ncbi Characteristics of dermatophytoses among children in an area south of Tehran, Iran
    A Rastegar Lari
    Department of Microbiology, Iran University of Medical Sciences, Tehran, Iran
    Mycoses 48:32-7. 2005
    ..6 per 100 000 person-years. Trichophyton violaceum was the most frequent isolate (28.3%) followed by Microsporum canis (15.1%), Epidermophyton floccosum (15.1%), T. rubrum (13.2%), T. mentagrophytes (11.3%), M. gypseum (7...
  56. ncbi In vitro activity of panomycocin, a novel exo-beta-1,3-glucanase isolated from Pichia anomala NCYC 434, against dermatophytes
    Fatih Izgu
    Department of Biological Sciences, Middle East Technical University, Ankara, Turkey
    Mycoses 50:31-4. 2007
    ..All the tested isolates (Microsporum spp. and Trichophyton spp.) were found susceptible to panomycocin. The MIC-2 values ranged from 0...
  57. ncbi Epidemiology of dermatomycoses in children living in Northern Greece 1996-2000
    Thalia Koussidou-Eremondi
    State Hospital for Skin and Venereal Diseases, Thessaloniki, Greece
    Mycoses 48:11-6. 2005
    ..There was a greater proportion of cases in the age range 2-12 years. The most prominent fungus was Microsporum canis (515 cases) followed by Trichophyton rubrum (34) and Candida albicans (20)...
  58. ncbi The epidemiology of canine and feline dermatophytoses in southern Italy
    C Cafarchia
    Dipartimento di Sanità e Benessere Animale, Facolta di Medicina Veterinaria, Bari, Italy
    Mycoses 47:508-13. 2004
    ..3%) yielded a positive culture and, in particular, 20.5% of the dog samples and 28.2% of the cat samples. Microsporum canis was the most common dermatophyte isolated from dogs and cats (77...
  59. ncbi Myths and misconceptions: not all that glitters under the watch is gold (nickel) dermatitis
    Ronni Wolf
    Dermatology Unit, Kaplan Medical Center, 76100 Rechovot, Israel
    Skinmed 3:344. 2004
  60. ncbi Origins of onychomycosis
    Daniel J McCarthy
    American Society of Podiatric Dermatology, 900 West Market Street, Akron, OH 44313, USA
    Clin Podiatr Med Surg 21:533-53, vi. 2004
    ..This article discusses the origins of this condition as well as methods of classification and evaluation...
  61. ncbi Seasonal 4-year investigation into the role of the alpine marmot (Marmota marmota) as a carrier of zoophilic dermatophytes
    M G Gallo
    Dipartimento di Produzioni Animali, Epidemiologia ed Ecologia, Sezione Parassitologia e Malattie Parassitarie, Grugliasco, Turin, Italy
    Med Mycol 43:373-9. 2005
    ..5%). Two species were zoophilic, Microsporum canis (7.8%) and Trichophyton mentagrophytes (11.2.%), and four geophilic, Microsporum cookei (2%), M...
  62. ncbi Eighty-four consecutive cases of tinea faciei in Siena, a retrospective study (1989-2003)
    C Romano
    Dipartimento di Medicina Clinica e Scienze Immunologiche, Sezione di Dermatologia, Siena University, Siena, Italy
    Mycoses 48:343-6. 2005
    ..2 years). The dermatophytes most frequently isolated were Microsporum canis (38 cases) and Trichophyton rubrum (31 cases). Clinical form was typical of tinea in 54 subjects (64...
  63. ncbi [Enzyme activities of dermatophytes isolated from different clinical samples by ApiZYM method]
    Nurver Ulger Toprak
    Marmara Universitesi Tip Fakultesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dali, Istanbul
    Mikrobiyol Bul 39:183-9. 2005
    ..From 11 acute cases; five Epidermophyton floccosum, three Trichophyton rubrum, two Microsporum canis and one Trichophyton mentagrophytes strains were isolated. Of the 47 chronic cases, 96% was due to T...
  64. ncbi Systemic antifungal therapy for cutaneous infections in children
    Aisha Sethi
    Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA
    Pediatr Infect Dis J 25:643-4. 2006
  65. ncbi Tinea incognito in Italy: a 15-year survey
    C Romano
    Institute of Dermatological Sciences, University of Siena, Via Monte Santo 3, 53100 Siena, Italy
    Mycoses 49:383-7. 2006
    ..In order of decreasing frequency, Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum canis, Microsporum gypseum, Trichophyton violaceum and Trichophyton erinacei were isolated...
  66. ncbi [Superficial fungal infections. Epidemiologic, clinical and mycologic study over a three year period]
    D El Euch
    Service de Dermatologie, Hopital La Rabta, Tunis, Tunisie
    Tunis Med 84:407-10. 2006
    ..Any time, Candida albicans is prevalent on the level of the hands...
  67. ncbi Epidemiology of dermatophytic infections in Rome, Italy: a retrospective study from 2002 to 2004
    V Panasiti
    Department of Dermatology, University La Sapienza, Viale del Policlinico, Rome, Italy
    Med Mycol 45:57-60. 2007
    ..7%) of these had infections caused by dermatophytes. The dermatophyte most frequently isolated was Microsporum canis...
  68. ncbi Analysis of the dermatophyte species isolated in the British Isles between 1980 and 2005 and review of worldwide dermatophyte trends over the last three decades
    Andrew M Borman
    Health Protection Agency, Mycology Reference Laboratory, Bristol, UK
    Med Mycol 45:131-41. 2007
    ..The relative frequencies of isolations of Microsporum canis (cat and dog ringworm), Trichophyton verrucosum (cattle ringworm), T. mentagrophytes var...
  69. ncbi Tinea capitis: ringworm of the scalp
    C Seebacher
    Mycoses 50:218-26. 2007
    ..The guideline tinea capitis, as passed by three German medical societies, is presented in the present study...
  70. ncbi [Epidemiology, etiology and clinical presentation of dermatophytosis in Pernambuco, 1995-2005]
    Paula Maria Rodrigues de Barros Corrêa Damázio
    Centro de Ciencias da Saude, Universidade Federal de Pernambuco, Recife, PE
    Rev Soc Bras Med Trop 40:484-6. 2007
    ..5%) and Trichophyton rubrum (34%) were the most frequent between 2000 and 2005. A significant reduction in Trichophyton mentagrophytes was detected in the second of these periods...
  71. ncbi [Resistance to azolic compounds in clinical Trichophyton spp. strains]
    Luis Javier Méndez-Tovar
    Laboratorio de Investigación Médica en Dermatología y Micología Dr Ernesto Macotela, Hospital de Especialidades Dr Bernardo Sepúlveda, UMAE Centro Médico Nacional Siglo XXI, IMSS, Mexico D F, Mexico
    Rev Iberoam Micol 24:320-2. 2007
    ..It is important to establish the antifungal susceptibility as part of the study procedures in patients with dermatophytosis and a poor antifungal response...
  72. ncbi Species distribution and antifungal susceptibilities of dermatophytes during a one year period at a university hospital in Turkey
    Aydan Ozkutuk
    Department of Microbiology and Clinical Microbiology, Dokuz Eylul University School of Medicine, Inciralti Izmir, Turkey
    Mycoses 50:125-9. 2007
    ..mentagrophytes (38%), T. violaceum (1.5%), T. verrucosum (1.5%), Microsporum canis (1.5%) and Epidermophyton floccosum (1.5%)...
  73. ncbi How do dermatophytes survive in the epidermis?
    Roderick J Hay
    Curr Opin Infect Dis 19:125-6. 2006
  74. ncbi Survey of dermatophytes on clinically normal cats in the southeast of England
    A Patel
    Dermatology Unit, Department of Veterinary Clinical Sciences, Royal Veterinary College, Hatfield, Hertfordshire
    J Small Anim Pract 46:436-9. 2005
    ..Asymptomatic cats are often blamed for transmission of dermatophytes between animals and humans. This study may help to clarify whether cats are responsible for the increase in fungal infections among the human population...
  75. ncbi Reconstructed interfollicular feline epidermis as a model for the screening of antifungal drugs against Microsporum canis
    Jeremy Tabart
    Department of Parasitology and Parasitic Diseases, Faculty of Veterinary Medicine, University of Liege, Liege, Belgium
    Vet Dermatol 19:130-3. 2008
    ..It was shown to be relevant for the study of Microsporum canis-epidermal interactions...
  76. ncbi Eastern cottontail (sylvilagus floridanus) as carrier of dermatophyte fungi
    M G Gallo
    Department of Animal Production Epidemiology and Ecology, University of Turin, Grugliasco, TO, Italy
    Mycopathologia 160:163-6. 2005
    ..As Eastern cottontail has been showed to be a carrier of dermatophytes transmissible to man (M. canis, T. mentagrophytes and M. gypseum), it may represent a source of infection for gamekeepers, hunters and veterinarians...
  77. ncbi Prevalence of dermatophytic fungal infections in children: a recent study in Anambra state, Nigeria
    E I Nweze
    Department of Microbiology, University of Nigeria, Nsukka, Enugu State, Nigeria
    Mycopathologia 160:239-43. 2005
    ..Trichophyton tonsurans was the most prevalent etiological agent while Microsporum audouinii was the least in occurrence...
  78. ncbi Pharmacokinetics of terbinafine in young children treated for tinea capitis
    Susan M Abdel-Rahman
    Children s Mercy Hospital, Kansas City, MO, USA
    Pediatr Infect Dis J 24:886-91. 2005
    ..This investigation was designed to evaluate the single dose and steady state pharmacokinetics of terbinafine in young children with tinea capitis...
  79. ncbi Inhibition of the growth in vitro of Trichophyton mentagrophytes, Trichophyton erinacei and Microsporum persicolor by miconazole and chlorhexidine
    Natalie Perrins
    Department of Veterinary Clinical Sciences, Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Herts AL9 7TA, UK
    Vet Dermatol 16:330-3. 2005
    ..agents for 9 isolates of Trichophyton mentagrophytes, 9 isolates of Trichophyton erinacei and 5 isolates of Microsporum persicolor...
  80. ncbi Clinical diagnosis of common scalp disorders
    Boni E Elewski
    Department of Dermatology, University of Alabama, Birmingham, AL 35294, USA
    J Investig Dermatol Symp Proc 10:190-3. 2005
    ..Diagnostic techniques and effective treatment strategies for each of the above conditions will be discussed...
  81. ncbi Dermatophytoses in monterrey, méxico
    Oliverio Welsh
    Servicio de Dermatologia, Hospital Universitario José E González, Monterrey, NL, Mexico
    Mycoses 49:119-23. 2006
    ..7%), Trichophyton tonsurans (21%), Microsporum canis (7.1%) and Epidermophyton floccosum (2.5%)...
  82. ncbi PCR-RFLP analysis of the dermatophytes isolated from patients in Central Poland
    Anita Dobrowolska
    J Dermatol Sci 42:71-4. 2006
  83. pmc Single-step PCR using (GACA)4 primer: utility for rapid identification of dermatophyte species and strains
    Atef S Shehata
    Microbiology Department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt
    J Clin Microbiol 46:2641-5. 2008
    Dermatophytes are fungi that belong to three genera: Epidermophyton, Microsporum, and Trichophyton. Identification of dermatophyte species is essential for appropriate diagnosis and treatment of dermatophytosis...
  84. ncbi Abbreviated oral itraconazole therapy for tinea corporis and tinea cruris
    B Sanmano
    Department of Dermatology, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, 113 8421 Tokyo, Japan
    Mycoses 46:316-21. 2003
    ..We conclude that an abbreviated oral regimen of itraconazole for treatment of tinea corporis and tinea cruris requires a total dose of at least 400 mg to induce a favorable outcome...
  85. ncbi Direct detection of dermatophytes in skin samples based on sequences of the chitin synthase 1 (CHS1) gene
    Rui Kano
    Department of Pathobiology, Nihon University School of Veterinary Medicine, Kanagawa, Japan
    J Vet Med Sci 65:267-70. 2003
    ..By PCR analysis with the primer pair, dermatophyte DNA could be diagnosed directly and rapidly in clinical skin samples...
  86. ncbi [Analysis of dermatophyte flora at a private clinic in Sapporo during the period 1992 to 2001]
    Hideomi Shibaki
    Shibaki Dermatology Clinic, Teine honcho 2 4, Teine ku, Sapporo 006 0022
    Nihon Ishinkin Gakkai Zasshi 44:209-16. 2003
    ..Trichophyton rubrum (TR)(79.4%), Trichophyton mentagrophytes (TM)(19.5%), Microsporum canis (MC)(0.7%), Epidermophyton floccosum (EF) (0.3%), and Microsporum gypseum (MG) (0.1%)...
  87. ncbi [Prevalence of zoophilic dermatophytes in the Sarajevo region]
    Asja Prohic
    Dermatoveneroloska klinika Klinicki Centar Univerziteta Sarajevo
    Med Arh 57:101-4. 2003
    ..Zoophilic dermatophytes were found in 421 (90.5%) patients. The most common zoophilic species was Microsporum canis (80...
  88. ncbi Dermatomycoses in the Rijeka area, Croatia, before, during and after the war 1990-1999
    Ines Brajac
    Department of Dermatovenerology, Clinical Hospital Centre Rijeka, Rijeka, Croatia
    Mycoses 46:213-7. 2003
    ..The most frequently isolated dermatophytes were in both periods Trichophyton mentagrophytes and Microsporum canis, followed by Microsporum gypseum, Epidermophyton floccosum, Trichophyton verrucosum and in the first ..
  89. ncbi In vitro antagonistic activity of monoterpenes and their mixtures against 'toe nail fungus' pathogens
    Russel S Ramsewak
    Department of Horticulture and National Food Safety and Toxicology Center, Michigan State University, East Lansing, Michigan 48824, USA
    Phytother Res 17:376-9. 2003
    ..responsible for onychomycosis, such as the dermatophytes Tricophyton rubrum, Trichophyton mentagrophytes, Microsporum canis, Epidermophyton fl occosum and Epidermophyton stockdale...
  90. ncbi Safety and immunologic effects after inoculation of inactivated and combined live-inactivated dermatophytosis vaccines in cats
    Douglas J Deboer
    Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison 53706, USA
    Am J Vet Res 63:1532-7. 2002
    ....
  91. ncbi Characteristics of dermatophytoses in children treated at the Department of Dermatology and Venerology, Dr Josip Bencevic General Hospital, Slavonski Brod, Croatia, from February 1993 till February 2000
    Mirna Tomljanović-Veselski
    Department of Dermatology and Venerology, Dr Josip Bencevic General Hospital, Slavonski Brod, Croatia
    Acta Dermatovenerol Croat 10:151-4. 2002
    ..97%) male and 151 (49.03%) female children aged 3 months to 15 years. Microsporum spp. infection was detected in 251 (81.49%) and Trichophyton spp. infection in 57 (18.51%) cases...
  92. ncbi Chemical analysis and antifungal activity of the essential oil of Calea clematidea
    Adriana Flach
    Departamento de Química da Universidade Federal de Santa Maria, Campus Camobi, Santa Maria, RS, Brazil
    Planta Med 68:836-8. 2002
    ..i nterdigitale, Epidermophyton floccosum, Microsporum gypseum, Microsporum canis and Microsporum nanum.
  93. ncbi New treatments for tinea capitis
    Yuin Chew Chan
    National Skin Centre, 1 Mandalay Road, Singapore 308205
    Curr Opin Infect Dis 17:97-103. 2004
    ..The predominant pathogen varies according to the geographical location. Trichophyton tonsurans and Microsporum canis account for the majority of infections in north America and certain parts of Europe...
  94. ncbi Differentiating the dermatophytes
    Jeremy R Caddell
    Mayo Foundation, Rochester, MN 55905, USA
    Clin Lab Sci 15:13-5. 2002
  95. ncbi [Dermatophyte flora at the dermatology clinic of Kimitsu Chuo Hospital from 1994 through 1999]
    Yoko Takahashi
    Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba 260 8673, Japan
    Nihon Ishinkin Gakkai Zasshi 43:21-7. 2002
    ..7%) of Trichophyton rubrum, 651 (40.4%) of T. mentagrophytes, 9 (0.6%) of Microsporum gypseum, 8 (0.5%) of M. canis, 8 (0.5%) of Epidermophyton floccosum and 5 (0.3%) of T. violaceum...
  96. ncbi In vitro susceptibility of Microsporum canis and other dermatophyte isolates from veterinary infections during therapy with terbinafine or griseofulvin
    B Hofbauer
    Infectious Diseases Department, Novartis Research Institute, Vienna, Austria
    Med Mycol 40:179-83. 2002
    We investigated the in vitro activity of terbinafine against fresh veterinary isolates of Microsporum canis and the potential of this organism to develop resistance in vivo during oral therapy...
  97. ncbi Incidence of dermatophytes and cyclohexamide resistant fungi on healthy children hairs and nails in nurseries
    S M Maghazy
    Botany Department, Faculty of Science, Minia University, Egypt
    Mycopathologia 154:171-5. 2002
    ..From hair samples 22 species were collected, Trichophyton (2 species) and Microsporum (2 species) were the only recovered dermatophytes in addition to well known keratinophilic genus Chrysosporium (..
  98. ncbi Parmelia cirrhatum: a potential source of broad spectrum natural antifungal
    Sushil K Shahi
    Botany Department, University of Allahabad, Allahabad 211002, India
    Phytother Res 17:399-400. 2003
    ..The extract did not showed any irritation on mammalian skin up to 10% concentration. Thus, the water extract of Parmelia cirrhatum can be used a potential source of natural antifungal against fungal infections...
  99. ncbi Inhibition of dermatophytes by optical brighteners
    J Brasch
    Department of Dermatology, University of Kiel, Kiel, Germany
    Mycoses 46:120-5. 2003
    ..Typical strains of Trichophyton rubrum, T. mentagrophytes, Microsporum canis and Epidermophyton floccosum were grown on agar plates containing two different brighteners of ..
  100. ncbi Sertaconazole: a review of its use in the management of superficial mycoses in dermatology and gynaecology
    Jamie D Croxtall
    Wolters Kluwer Health Adis, Auckland, New Zealand
    Drugs 69:339-59. 2009
    ..has broad-spectrum antifungal activity against dermatophytes of the Trichophyton, Epidermophyton and Microsporum genera, and yeasts of the genera Candida and Cryptococcus; additionally, it is effective against opportunistic ..
  101. ncbi An overview of topical antifungal therapy in dermatomycoses. A North American perspective
    A K Gupta
    Department of Medicine, Sunnybrook Health Science Center, Toronto, Ontario, Canada
    Drugs 55:645-74. 1998
    ..g. skin, hair and nails. The organisms belong to 3 genera, Trichophyton, Epidermophyton and Microsporum. Dermatophytes may be grouped into 3 categories based on host preference and natural habitat...

Research Grants2

  1. MECHANISM OF IL-12 INHIBITION BY CANDIDA ALBICANS
    Mahmoud Ghannoum; Fiscal Year: 2009
    ..Data obtained from these studies will lead to a better understanding of the complex immune response to CA infection and may identify novel prevention/treatment strategies for candidiasis. ..
  2. Biology and Drug Resistance of Candida Biofilms
    Mahmoud Ghannoum; Fiscal Year: 2005
    ..albicans biofilms. By studying biofilm model systems and applying this knowledge to the patient population, we will gain a wealth of data about the biology and drug resistance of C. albicans in biofilms. ..