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Species | calotropisSummarySummary: A plant genus of the family ASCLEPIADACEAE. The downy akund floss fiber from the seeds is used like kapok. Top Publications
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Publications
Preliminary study on antifertility activity of Calotropis procera roots in female rats
Jagadish V Kamath
Department of Pharmacology, Krupanidhi College of Pharmacy, Sarjapur Road, Kormanagala, Bangalore 560 034, India
Fitoterapia 73:111-5. 2002The effect of ethanolic extract of the roots of Calotropis procera has been studied in albino rats to explore its antifertility and hormonal activities...Studies on anti-diarrhoeal activity of Calotropis gigantea R.Br. in experimental animals
Havagiray R Chitme
Institute of Pharmacy, Bundelkhand University, Jhansi, Uttar Pradesh, India
J Pharm Pharm Sci 7:70-5. 2004b>Calotropis gigantea R. Br. (Asclepiadaceae) a wildly growing plant has been reported to possess number of medicinal properties and other purposes...Calotropis procera latex extract affords protection against inflammation and oxidative stress in Freund's complete adjuvant-induced monoarthritis in rats
Vijay L Kumar
Department of Pharmacology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, India
Mediators Inflamm 2007:47523. 2007In view of the well-established anti-inflammatory properties of latex of Calotropis procera (DL), the present study was carried out to evaluate the protective effect of its methanol extract (MeDL) against inflammation and oxidative stress ..Control of Musca domestica third instar larvae by the latex of Calotropis procera (Family: Asclepiadaceae)
T A Morsy
Department of Parasitology, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt
J Egypt Soc Parasitol 31:107-10. 2001b>Calotropis procera (Family: Asclepiadaceae) is known to contain alkaloids, steroids and resinous substance. Different concentrations of its latex were topically applied to the 3rd stage larvae of Musca domestica...19-Nor- and 18,20-epoxy-cardenolides from the leaves of Calotropis gigantea
Thitima Lhinhatrakool
Department of Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkapi, Bangkok 10240, Thailand
J Nat Prod 69:1249-51. 2006..1 and 2) along with 12 known compounds were isolated from the dichloromethane extract of the leaves of Calotropis gigantea. The structural elucidation was accomplished by spectroscopic methods...Anti-inflammatory and gastromucosal protective effects of Calotropis procera (Asclepiadaceae) stem bark
Nagesh Tour
R C Patel Institute of Pharmaceutical Education and Research, Maharashtra, India
J Nat Med 65:598-605. 2011..gastromucosal protective effect of chloroform extract (CH) and hydroalcoholic extract (HE) of the stem bark of Calotropis procera obtained successively by cold maceration...Proteins from latex of Calotropis procera prevent septic shock due to lethal infection by Salmonella enterica serovar Typhimurium
José V Lima-Filho
Departamento de Biologia, Universidade Federal Rural de Pernambuco, Campus Dois Irmãos, Recife, PE, Brazil
J Ethnopharmacol 129:327-34. 2010The latex of Calotropis procera has been used in traditional medicine to treat different inflammatory diseases. The anti-inflammatory activity of latex proteins (LP) has been well documented using different inflammatory models...Extraction and phytochemical investigation of Calotropis procera: effect of plant extracts on the activity of diverse muscles
A M Y Moustafa
Chemistry Department, Faculty of Science, Suez Canal University, Port Said, Egypt
Pharm Biol 48:1080-190. 2010b>Calotropis procera (Ait.) R.Br. (Asclepiadaceae) is a shrub or small tree that grows wild in Egypt...Antimycoplasmal activity of some plant species from northern Nigeria compared to the currently used therapeutic agent
I A Muraina
Phytomedicine Programme, University of Pretoria, Onderstepoort, South Africa
Pharm Biol 48:1103-7. 2010..are obligate parasites of humans and animals. But due to the special requirements needed to culture Mycoplasma in the laboratory, little or no research has been done to evaluate the efficacy of medicinal plants on the organism...In vitro cytotoxicity against different human cancer cell lines of laticifer proteins of Calotropis procera (Ait.) R. Br
Jefferson Soares de Oliveira
Departamento de Bioquimica e Biologia Molecular, Universidade Federal do Ceara, Campus do Pici, Caixa Postal 6033, CEP 60 451 970, Fortaleza, Ceara, Brazil
Toxicol In Vitro 21:1563-73. 2007..the in vitro cytotoxic activity of laticifer proteins (LP) recovered from the latex of the medicinal plant Calotropis procera. The LP displayed considerable cytotoxicity with IC(50) values ranging from 0.42 to 1...Latex constituents from Calotropis procera (R. Br.) display toxicity upon egg hatching and larvae of Aedes aegypti (Linn.)
Márcio Viana Ramos
Departamento de Bioquimica e Biologia Molecular, Universidade Federal do Ceara, Campus do Pici, 60451 970 Fortaleza, CE, Brasil
Mem Inst Oswaldo Cruz 101:503-10. 2006b>Calotropis procera R. Br. (Asclepiadaceae) is a well-known medicinal plant with leaves, roots, and bark being exploited by popular medicine to fight many human and animal diseases...Anticancer and cytotoxic properties of the latex of Calotropis procera in a transgenic mouse model of hepatocellular carcinoma
Tenzin Choedon
International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
World J Gastroenterol 12:2517-22. 2006To evaluate the anticancer property of the dried latex (DL) of Calotropis procera, a tropical medicinal plant, in the X15-myc transgenic mouse model of hepatocellular carcinoma and to elucidate its mechanism of action in cell culture.In vivo growth inhibition of sarcoma 180 by latex proteins from Calotropis procera
Jefferson S Oliveira
Departamento de Bioquimica e Biologia Molecular, Universidade Federal do Ceara, Campus do Pici, Caixa Postal 6033, 60 451 970, Fortaleza, Ceara, Brazil
Naunyn Schmiedebergs Arch Pharmacol 382:139-49. 2010Latex of Calotropis procera has been described as a relevant source of pharmacologically active proteins, including proteins with anticancer activity. A previous in vitro study of laticifer proteins (LP) from C...Clinical and pathological effects of Calotropis procera exposure in sheep and rats
Joseney Maia de Lima
Department of Animal Sciences, Universidade Federal Rural do Semi Arido UFERSA, BR 110 Km 47, Mossoró, RN 59625 900, Brazil
Toxicon 57:183-5. 2011This study aimed to describe the toxic effects resulting from the administration of Calotropis procera (Aiton) W. T. Aiton latex to rats and C. procera leaves to sheep. We studied male sheep that received C. procera leaves by gavage...Osmotin from Calotropis procera latex: new insights into structure and antifungal properties
Cléverson Diniz Teixeira de Freitas
Departamento de Biologia, Universidade Federal do Piaui, Bairro Melladão, Floriano Piauí, Brazil
Biochim Biophys Acta 1808:2501-7. 2011..the structural properties and mechanisms of the antifungal action of CpOsm, a purified osmotin from Calotropis procera latex...Lupeol, a triterpenoid isolated from Calotropis gigantea latex ameliorates the primary and secondary complications of FCA induced adjuvant disease in experimental rats
Venkatesan Saratha
Department of Biochemistry, University of Madras, Guindy Campus, Chennai 600025, Tamilnadu, India
Inflammopharmacology 20:27-37. 2012..b>Calotropis gigantea is a xerophytic, latex producing medicinal plant widely distributed in nature...Exploring applications of procerain b, a novel protease from Calotropis procera, and characterization by N-terminal sequencing as well as peptide mass fingerprinting
Abhay Narayan Singh
Department of Biotechnology, Indian Institute of Technology Guwahati, Guwahati, 781039, Assam, India
Appl Biochem Biotechnol 164:573-80. 2011Procerain B is a novel cysteine protease isolated from Calotropis procera by our group and published recently. We have further characterized the enzyme by N-terminal sequencing and peptide mass fingerprinting...Evaluation of cytotoxic potential of latex of Calotropis procera and podophyllotoxin in Allium cepa root model
R Sehgal
Department of Pharmacology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, India
Biocell 30:9-13. 2006..the Allium cepa root tip meristem model to evaluate the cytotoxic and anti-mitotic activities of latex of Calotropis procera (DL) and podophyllotoxin...Hepatoprotective effects of Calotropis gigantea extract against carbon tetrachloride induced liver injury in rats
Gaurav Lodhi
Department of Pharmacology and Therapeutics, Chatrapati Sahuji Maharaj Medical University, Lucknow 226003, India
Acta Pharm 59:89-96. 2009Ethanolic extract (50 %) of stems of Calotropis gigantea R. Br...Hepatoprotective activity of Calotropis procera flowers against paracetamol-induced hepatic injury in rats
S Ramachandra Setty
Department of Pharmacology, S C S College of Pharmacy, Davanagere, Karnataka, India
Fitoterapia 78:451-4. 2007Hydro-ethanolic extract (70%) of Calotropis procera flowers was prepared and tested for its hepatoprotective effect against paracetamol-induced hepatitis in rats...In vitro and in vivo antiproliferative activity of Calotropis procera stem extracts
Hemerson I F Magalhães
Departamento de Fisiologia e Farmacologia, Universidade Federal do Ceará Campus do Porangabussu, Fortaleza, CE, Brasil
An Acad Bras Cienc 82:407-16. 2010The cytotoxic potential of stem organic extracts from Calotropis procera (Asclepiadaceae) was firstly evaluated against cancer cell lines by MTT assay...Identification of Calotropis procera L. as a potential phytoaccumulator of heavy metals from contaminated soils in Urban North Central India
Rohan J D'Souza
Department of Botany, St John s College, Agra 282 002, India rohan
J Hazard Mater 184:457-64. 2010..b>Calotropis procera, a hardy xerophytic plant was identified and selected for remedial potential as it was seen growing well ..Procerain, a stable cysteine protease from the latex of Calotropis procera
Vikash Kumar Dubey
Molecular Biology Unit, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India
Phytochemistry 62:1057-71. 2003A protease was purified to homogeneity from the latex of medicinal plant Calotropis procera (Family-Asclepiadaceae). The molecular mass and isoelectric point of the enzyme are 28.8 kDa and 9.32, respectively...A new cytotoxic pregnanone from Calotropis gigantea
Zhu Nian Wang
Institute of Crops Genetic Resources, Chinese Academy of Tropical Agricultural Sciences, Danzhou 571737, P R China
Molecules 13:3033-9. 2008A new pregnanone, named calotropone (1), was isolated from the EtOH extract of the roots of Calotropis gigantea L. together with a known cardiac glycoside. The structures were elucidated by a study of their physical and spectral data...Antioxidant and protective effect of latex of Calotropis procera against alloxan-induced diabetes in rats
S Roy
Department of Pharmacology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi
J Ethnopharmacol 102:470-3. 2005In the present study, dry latex (DL) of Calotropis procera possessing potent anti-inflammatory activity was evaluated for its antioxidant and anti-hyperglycemic effects against alloxan-induced diabetes in rats...Procoagulant activity of Calotropis gigantea latex associated with fibrin(ogen)olytic activity
R Rajesh
Department of Studies in Biochemistry, University of Mysore, Manasagangothri, Mysore 570 006, Karnataka, India
Toxicon 46:84-92. 2005The latex of Calotropis gigantea is a rich source of useful components that has medicinal properties and one of the main applications is in controlling bleeding...A comparative study on the efficacy of rofecoxib in monoarticular arthritis induced by latex of Calotropis procera and Freund's complete adjuvant
V L Kumar
Department of Pharmacology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India
Inflammopharmacology 14:17-21. 2006The role of prostaglandins in Calotropis procera latex induced inflammation and hyperalgesia has been well established...Calotropis procera (Sodom apple)--a potential material for enzyme purification
S O Kareem
Department of Microbiology, University of Agriculture, P M B 2240, Abeokuta, Nigeria
Bioresour Technol 87:133-5. 2003A simple method based on precipitation with Calotropis procera latex was developed for the purification of crude enzyme from fermentation broth. C...Cytotoxic cardenolides from the leaves of Calotropis gigantea
Chonticha Seeka
Department of Chemistry and Center for Innovation in Chemistry, Faculty of Science, Ramkhamhaeng University, Ramkhamhaeng Road, Bangkapi, Bangkok 10240, Thailand
Chem Pharm Bull (Tokyo) 58:725-8. 2010..The isolated compounds were evaluated for their inhibitory activities against a panel of cell lines...Involvement of prostaglandins in inflammation induced by latex of Calotropis procera
Vijay L Kumar
Department of Pharmacology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029
Mediators Inflamm 13:151-5. 2004The aerial parts of the plant Calotropis procera produce milky white latex that causes inflammation of the skin and mucous membranes...Enzymatic activities and protein profile of latex from Calotropis procera
Cleverson Diniz T Freitas
Departamento de Bioquímica e Biologia Molecular da Universidade Federal do Ceará, Campus do Pici, Cx Postal 6033, Fortaleza, Ceará CEP 60451 970, Brazil
Plant Physiol Biochem 45:781-9. 2007The laticifer fluid of Calotropis procera is rich in proteins and there is evidence that they are involved in the pharmacological properties of the latex...Phytoremediation of radiostrontium ((90)Sr) and radiocesium ((137)Cs) using giant milky weed (Calotropis gigantea R.Br.) plants
Susan Eapen
Nuclear Agriculture and Biotechnology Division, Bhabha Atomic Research Centre, Mumbai 400085, India
Chemosphere 65:2071-3. 2006..When uptake of (137)Cs and (90)Sr by Calotropis gigantea plants incubated in distilled water spiked with the radionuclides either alone or in combination was ..Antiinflammatory efficacy of extracts of latex of Calotropis procera against different mediators of inflammation
Soneera Arya
Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India
Mediators Inflamm 2005:228-32. 2005The latex of the plant Calotropis procera has been reported to exhibit potent antiinflammatory activity against carrageenin and formalin that are known to release various mediators...Histamine mediates the pro-inflammatory effect of latex of Calotropis procera in rats
Yatin M Shivkar
Department of Pharmacology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, India
Mediators Inflamm 12:299-302. 2003INTRODUCTiON: Calotropis procera is known to produce contact dermatitis and the latex of this plant produces intense inflammation when injected locally. However, the precise mode of its pro-inflammatory effect is not known...Calotropis procera latex-induced inflammatory hyperalgesia--effect of antiinflammatory drugs
Raman Sehgal
Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India
Mediators Inflamm 2005:216-20. 2005The milky white latex of plant Calotropis procera produces inflammation of the skin and mucous membranes on accidental exposure...Analgesic activity of Calotropis gigantea flower
A K Pathak
Department of Pharmacy, Barkatullah University, Bhopal, MP 462026, India
Fitoterapia 78:40-2. 2007The alcoholic extract of the flowers of Calotropis gigantea was administered orally and explored for its analgesic activity in chemical and thermal models in mice. In acetic acid induced writhing test, an inhibition of 20.97% and 43...Calotropis procera (ushaar) keratitis
Hani S Al-Mezaine
Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia
Am J Ophthalmol 139:199-202. 2005To report a case of permanent endothelial cell injury after intracorneal penetration of milky latex from Calotropis procera (ushaar).Evaluation of anti-inflammatory activity of Calotropis gigantea (AKANDA) in various biological system
Manoranjan Adak
Department of Biochemistry, National Medical College Teaching Hospital, Birgunj, Nepal
Nepal Med Coll J 8:156-61. 2006To evaluate the effect of Calotropis G in various experimental animal models...Wound healing activity of Calotropis gigantea root bark in rats
Pradeep T Deshmukh
Department of Pharmacology, BR Nahata College of Pharmacy, Mhow Neemuch Road, Mandsaur 458001, Madhya Pradesh, India
J Ethnopharmacol 125:178-81. 2009b>Calotropis gigantea R.Br. (Asclepiadaceae) is a perennial undershrub found chiefly in wastelands throughout India. It has been reported as a traditional folkloric medicine for a variety of alignments...Isolation of stigmasterol and beta-sitosterol from methanolic extract of root bark of Calotropis gigantea (Linn)
M Rowshanul Habib
Department of Biochemistry and Molecular Biology, Rajshahi University, Rajshahi 6205, Bangladesh
Pak J Biol Sci 10:4174-6. 2007Aim of this study is to identify and characterize the bioactive principles from the root bark of Calotropis gigantea. It has wide folk medicinal use...Effect of anti-inflammatory drugs on pleurisy induced by latex of Calotropis procera in rats
Yatin M Shivkar
Department of Pharmacology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, India
Pharmacol Res 50:335-40. 2004In present study, we have characterized the inflammation induced by latex of Calotropis procera in the rat pleurisy model and evaluated the effect of various inhibitors of inflammatory mediators...Corneal endothelial cytotoxicity of the Calotropis procera (ushaar) plant
Hani S Al-Mezaine
Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia
Cornea 27:504-6. 2008To report 6 eyes of 5 patients with transient corneal edema after exposure to the milky latex of Calotropis procera (ushaar).Calotropis procera -induced keratitis
Nidhi Pandey
Department of Ophthalmology, Pt J N M Medical College, Raipur, India
Indian J Ophthalmol 57:58-60. 2009b>Calotropis procera produces copious amounts of latex, which has been shown to possess several pharmacological properities. Its local application produces intense inflammatory response...Pregnancy interceptive activity of the roots of Calotropis gigantea Linn. in rats
Shobha Rani Srivastava
Division of Endocrinology, Central Drug Research Institute, Lucknow 226 001, India
Contraception 75:318-22. 2007We conducted this study to evaluate the pregnancy interceptive activity of the roots of Calotropis gigantea Linn. in colony-bred adult Sprague-Dawley rats when administered during the preimplantation and/or peri-implantation periods.CNS activity of Calotropis gigantea roots
Ameeta Argal
Department of Pharmacy, Barkatullah University, Bhopal 462026, M P, India
J Ethnopharmacol 106:142-5. 2006Alcoholic extract of peeled roots of Calotropis gigantea R.Br. (Asclepiadaceae) was tested orally in albino rats at the dose level of 250 and 500 mg/kg bodyweight for CNS activity...Comparative study on plant latex proteases and their involvement in hemostasis: a special emphasis on clot inducing and dissolving properties
Rajaiah Rajesh
Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA
Planta Med 73:1061-7. 2007In the present study we compared the clot inducing and dissolving properties of Calotropis gigantea R. Br. (Asclepiadaceae), Synadenium grantii Hook. f. (Euphorbiaceae) and Wrightia tinctoria R. Br. (Apocynaceae) latex extracts...Immunological and allergenic responses induced by latex fractions of Calotropis procera (Ait.) R.Br
M V Ramos
Departamento de Bioquimica e Biologia Molecular, Campus do Pici, Universidade Federal do Ceara, Fortaleza, Ceara, CEP, Brazil
J Ethnopharmacol 111:115-22. 2007Immunological and allergenic responses against the latex of Calotropis procera were investigated in mice by oral and subcutaneous routes. The latex was fractionated according to water solubility and molecular size of its components...In vitro spasmolytic effect of aqueous extract of Calotropis procera on Guinea-pig trachea smooth muscle chain
Ezekiel O Iwalewa
Department of Pharmacology, Faculty of Pharmacy, Obafemi Awolowo University, Ile Ife, Nigeria
Fitoterapia 76:250-3. 2005The aqueous extract of Calotropis procera was evaluated for its spasmolytic effect using in vitro trachea smooth muscle chain of Guinea-pig...Latex proteins from the plant Calotropis procera are partially digested upon in vitro enzymatic action and are not immunologically detected in fecal material
Marcio V Ramos
Departamento de Bioquímica e Biologia Molecular da Universidade Federal do Ceará, Campus do Pici, Cx Postal 6033, Fortaleza Ceara, CEP 60451 970, Brazil
Fitoterapia 77:251-6. 2006Soluble proteins from the latex of Calotropis procera (LP) were investigated in vitro and in vivo for digestibility as the latex has previously been shown to produce considerable toxic effects on animals...Identification of a novel cardenolide (2''-oxovoruscharin) from Calotropis procera and the hemisynthesis of novel derivatives displaying potent in vitro antitumor activities and high in vivo tolerance: structure-activity relationship analyses
Eric Van Quaquebeke
Unibioscreen SA, 40 Avenue Joseph Wybran, 1070 Brussels, Belgium
J Med Chem 48:849-56. 2005Analysis of the methanolic extract of Calotropis procera root barks enabled the identification of a novel cardenolide (2''-oxovoruscharin) to be made...Ethnopharmacological survey of wild medicinal plants in Showbak, Jordan
S Al-Qura'n
Mu tah University, Faculty of Science, Department of Biology, P O Box 26, Mu tah, Karak, Jordan
J Ethnopharmacol 123:45-50. 2009..These plants include Calotropis procera Willd R.Br., Citrullus colocynthis (L.) Sch., Datura stramonium L., Digitalis purpurea L...Decontamination and/or revegetation of fly ash dykes through naturally growing plants
Amit K Gupta
Ecotoxicology and Bioremediation Group, National Botanical Research Institute, Rana Pratap Marg, Lucknow 226001, India
J Hazard Mater 153:1078-87. 2008..is focused on the decontamination and/or revegetation of fly ash dykes through naturally growing plants, namely Calotropis procera, Cassia tora, Chenopodium album, Sida cardifolia, Blumea lacera...[Traditional therapy of dracunculiasis in the state of Bauchi - Nigeria]
J P Fabiyi
Biological Sciences Programme, Abubakar Tafawa Balewa University, Bauchi, Nigeria
Dakar Med 38:193-5. 1993..In particular, Tamarindus indica, Adansonia digitata, Calotropis procera, Ziziphus jaozeiro and Moringa olifera are known in nature to have relevant medicinal properties ..Germinating seeds of the mung bean, Vigna radiata (Fabaceae), as a model for the preliminary evaluation of cytotoxic effects of drugs
Vijay L Kumar
Department of Pharmacology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, India
Biocell 33:19-24. 2009..0 to 1.5 cm (time 0, T0) and 48 h later (T48). Methanol extract of Calotropis procera latex as well as drugs like podophyllotoxin, cyclophosphamide, cyproheptadine and aspirin produced a ..Free Radical Scavenging Activity of Calotropis gigantea on Streptozotocin-Induced Diabetic Rats
N R Rathod
Department of Pharmacology, H S K College of Pharmacy, Bagalkot 587101, India
Indian J Pharm Sci 71:615-21. 2009Swarnabhasma, an Ayurvedic preparation containing Calotropis gigantea R. Br. (Asclepiadaceae) is extensively used by Ayurvedic physicians for treatment of diabetes mellitus, bronchial asthma, rheumatoid arthritis and nervous disorders...Potential of laticifer fluids for inhibiting Aedes aegypti larval development: evidence for the involvement of proteolytic activity
Marcio V Ramos
Departamento de Biologia, Universidade Federal do Ceara, Fortaleza, CE, Brasil, 60451 970
Mem Inst Oswaldo Cruz 104:805-12. 2009It has been shown previously that the laticifer fluid of Calotropis procera (Ait.) R.Br. is highly toxic to the egg hatching and larval development of Aedes aegypti L...Pharmacognostic standardization of leaves of Calotropis procera (Ait.) R. Br. (Asclepiadaceae)
Y Murti
Department of Pharmaceutical Chemistry, Rajiv Academy for Pharmacy, Mathura, N H 2, Delhi Mathura Bye pass, P O Chattikara, Mathura 281 001, U P, India
Int J Ayurveda Res 1:14-7. 2010b>Calotropis procera, belonging to the Asclepidaceae family, is present more or less throughout India and in other warm, dry places such as, Warizistan, Afghanistan, Egypt, and tropical Africa. Its common names are Akra, Akanal, and Madar...Tuareg ethnoveterinary treatments of camel diseases in Agadez area (Niger)
N Antoine-Moussiaux
Tropical Veterinary Institute, University of Liege, 20 Boulevard de Colonster, B43 4000 Liege, Belgium
Trop Anim Health Prod 39:83-9. 2007..in this survey are derived from Maerua crassifolia, Boscia senegalensis, Acacia raddiana, Cucumis prophetarum, Calotropis procera, Ricinus communis, Citrullus colocynthis, green tea, millet, tobacco and onions...Cytotoxic principles of a Bangladeshi crude drug, akond mul (roots of Calotropis gigantea L.)
F Kiuchi
Faculty of Pharmaceutical Sciences, Kanazawa University, Japan
Chem Pharm Bull (Tokyo) 46:528-30. 1998..and 4'-O-beta-D-glucopyranosylfrugoside (3), were obtained as the cytotoxic principles of "akond mul" (roots of Calotropis gigantea L.)...Biosorptive removal of Ni(Ii) from wastewater and industrial effluent
Piyush Kant Pandey
Centre for Environmental Science and Engineering, Department of Engineering Chemistry, Bhilai Institute of Technology, Durg, 491002 C G, India
Int J Environ Res Public Health 4:332-9. 2007..to investigate the removal of Ni(II) by the fresh biomass (FBM) and chemically treated leached biomass (LBM) of Calotropis procera...Biosorptive removal of cadmium from contaminated groundwater and industrial effluents
Piyush Kant Pandey
Centre for Environmental Science and Engineering, Department of Engineering Chemistry, Bhilai Institute of Technology, Durg, 491 002 CG, India
Bioresour Technol 99:4420-7. 2008The cadmium removing capacity of a biosorbent Calotropis procera, a perennial wild plant, is reported here. The biomass was found to possess high uptake capacity of Cd(II)...Suberized cell walls of cork from cork oak differ from other species
Rita Teresa Teixeira
Centro de Estudos Florestais, Instituto Superior de Agronomia, Universidade Tecnica de Lisboa, Portugal
Microsc Microanal 16:569-75. 2010..We observed cork cells from periderms of Quercus suber, Quercus cerris, Solanum tuberosum, and Calotropis procera by TEM after uranyl acetate and lead citrate staining. A lamellated structure was observed in S...Phytoextraction capacity of the plants growing on tannery sludge dumping sites
Amit K Gupta
Ecotoxicology and Bioremediation Group, National Botanical Research Institute, Rana Pratap Marg, Lucknow 226 001, India
Bioresour Technol 98:1788-94. 2007The study was undertaken to assess the phytoremediation potential of four plants (Sida acuta, Ricinus communis, Calotropis procera, Cassia fistula) growing at a tannery sludge disposal site...Effect of organic solvents on the molten globule state of procerain: beta-sheet to alpha-helix switchover in presence of trifluoroethanol
Vikash Kumar Dubey
Molecular Biology Unit, Institute of Medicinal Sciences, Banaras Hindu University, Varanasi 221 005, India
Protein Pept Lett 13:545-7. 2006..TFE) on the structure and folding of molten globule state of procerain, a cysteine protease from Calotropis procera, was studied by circular dichroism spectroscopy...Acaricidal effect of herbal extracts against cattle tick Rhipicephalus (Boophilus) microplus using in vitro studies
K P Shyma
Department of Parasitology, Sardar Krushinagar Dantiwada Agricultural University, Sardarkrushinagar, 385506, India
Parasitol Res 113:1919-26. 2014The crude methanolic extract of Datura stramonium, Azadirachta indica, and Calotropis procera leaves, Allium sativum (AS) cloves, and Carica papaya (CP) seeds collected from Banaskanta, Gujarat (India) was tested for its acaricidal ..Calotropis procera root extracts block VEGF-induced angiogenesis: quantitative analysis
Rajani Mathur
Department of Pharmacology, Delhi Institute of Pharmaceutical Sciences and Research, Pushp Vihar, M B Road, New Delhi 110 017
Indian J Physiol Pharmacol 55:5-12. 2011..In this study, methanolic (CM), n-hexane (CH), ethylacetate (CE) and water (CW) extracts of the roots of Calotropis procera were tested for anti-angiogenic activity...Laticifer proteins play a defensive role against hemibiotrophic and necrotrophic phytopathogens
Diego P Souza
Departamento de Bioquímica e Biologia, Molecular da Universidade Federal do Ceará, Campus do Pici, Cx Postal 6033, Fortaleza, Ceara, CEP 60451 970, Brazil
Planta 234:183-93. 2011Proteins from latex of Calotropis procera (CpLP), Plumeria rubra (PrLP), Carica candamarcensis (P1G10) and Euphorbia tirucalli (EtLP) were tested for antifungal activity against phytopathogens. CpLP and P1G10 inhibited each fungi analyzed...UNBS1450 from Calotropis procera as a regulator of signaling pathways involved in proliferation and cell death
Tom Juncker
Laboratoire de Biologie Moléculaire et Cellulaire du Cancer, Hopital Kirchberg, 9 rue Edward Steichen, L 2540 Luxembourg, Luxembourg
Biochem Pharmacol 78:1-10. 2009..For centuries it has been known that the coarse shrub Calotropis procera is a very promising source of ascaricidal, schizonticidal, anti-bacterial, anthelmintic, insecticidal, ..Comparative evaluation of the cytotoxic and apoptotic potential of Poecilocerus pictus and Calotropis gigantea
Caroline Mathen
Department of Animal Biotechnology, The Kelkar Education Trust s Scientific Research Centre, Mumbai, India
J Environ Pathol Toxicol Oncol 30:83-92. 2011b>Calotropis gigantea, the giant milkweed, is traditionally used for the treatment of cancer and in Ayurvedic medicine as an anti-helminthic, anti-pyretic, and anti-malarial agent. Poecilocerus pictus, an orthopteran insect, feeds on C...Rapid identification of calotropagenin glycosides using high-performance liquid chromatography electrospray ionisation tandem mass spectrometry
Sanjeev Kanojiya
Sophisticated Analytical Instrument Facility, Central Drug Research Institute, Lucknow 226001, India
Phytochem Anal 23:117-25. 2012Cardiac glycosides in Calotropis procera have therapeutic use as inhibitors of Na⁺/K⁺-ATPase to regulate heart contractions...Calotropis procera mediated combustion synthesis of ZnAl2O4:Cr(3+) nanophosphors: Structural and luminescence studies
B S Ravikumar
C N R Rao Centre for Advanced Materials, Tumkur University, Tumkur 572 103, India
Spectrochim Acta A Mol Biomol Spectrosc 136:1027-37. 2015ZnAl2O4:Cr(3+) nanophosphors were synthesized for the first time by a simple and environment friendly route using Calotropis procera milk latex as fuel...Acetaminophen-induced liver damage in mice: effects of some medicinal plants on the oxidative defense system
M Tolulope Olaleye
Departamento de Quimica, Centro de Ciencias Naturais e Exatas, Universidade Federal de Santa Maria, Programa de Pós Graduação em Ciências Biológicas Bioquímica Toxicológica, Camobi, CEP 97105 900, Santa Maria, RS, Brazil
Exp Toxicol Pathol 59:319-27. 2008..the possible protective effects of administration (100mg/kg) of some medicinal plants (Kigelia africana, Calotropis procera, Hibiscus sabdariffa and Alchornea cordifolia) on PCM-induced liver damage in mice...Effect of anhydrosophoradiol-3-acetate of Calotropis gigantea (Linn.) flower as antitumoric agent against Ehrlich's ascites carcinoma in mice
Muhammad R Habib
Department of Biochemistry and Molecular Biology, Faculty of Science, Rajshahi University, Rajshahi 6205, Bangladesh
Pharmacol Rep 65:761-7. 2013..b>Calotropis gigantea (Linn...Detection of a Usp-like gene in Calotropis procera plant from the de novo assembled genome contigs of the high-throughput sequencing dataset
Ahmed M Shokry
Department of Biological Sciences, Faculty of Science, King Abdulaziz University KAU, P O Box 80141, Jeddah 21589, Saudi Arabia Agricultural Genetic Engineering Research Institute AGERI, Agriculture Research Center ARC, Giza, Egypt
C R Biol 337:86-94. 2014The wild plant species Calotropis procera (C. procera) has many potential applications and beneficial uses in medicine, industry and ornamental field. It also represents an excellent source of genes for drought and salt tolerance...Water relations and photosynthetic capacity of two species of Calotropis in a tropical semi-arid ecosystem
Wilmer Tezara
Centro de Botánica Tropical, Instituto de Biologia Experimental, Universidad Central de Venezuela, Caracas 1041 A, Venezuela
Ann Bot 107:397-405. 2011b>Calotropis procera and Calotropis gigantea, originally from warm parts of Africa and Asia, are now pan-tropical and in ecological terms considered an indicator of overgrazed, disturbed lands; they grow successfully in dry areas...Effects of Calotropis procera on oestrous cycle and on oestrogenic functionality in rats
C Circosta
Pharmaco Biological Department, School of Pharmacy, University of Messina, Italy
Farmaco 56:373-8. 2001Effects of ethanolic and aqueous extracts of Calotropis procera (Ait.) R.Br. roots, have been studied on oestrous cycle and on some parameters of oestrogenic functionality in rats...Effect of railway engines emission on the micromorphology of some field plants
Mamta Rani
Botany Department, S S V P G, College, Hapur 245 101 India
J Environ Biol 27:373-6. 2006..The plants selected for the present studies included Croton bonplandianum, Cannabis sativa and Calotropis procera...Anti-inflammatory effect of the latex from Calotropis procera in three different experimental models: peritonitis, paw edema and hemorrhagic cystitis
N M N Alencar
Departamento de Farmacologia e Fisiologia, Universidade Federal do Ceara, Campus do Pici, Fortaleza Ceara, Brasil
Planta Med 70:1144-9. 2004Latex from Calotropis procera is widely used in folk medicine as a rich source of biologically active compounds capable of promoting diverse benefits such as control of dermal fungal infections, antimicrobial activities and pain relief ..Antibacterial and cytotoxic potential of silver nanoparticles synthesized using latex of Calotropis gigantea L
Chandrasekaran Rajkuberan
Department of Biotechnology and Genetic Engineering, Bharathidasan University, Tiruchirappalli 620024, Tamil Nadu, India
Spectrochim Acta A Mol Biomol Spectrosc 136:924-30. 2015..present study aimed to synthesis silver nanoparticles (AgNPs) in a greener route using aqueous latex extract of Calotropis gigantea L. toward biomedical applications...Cola soft drinks for evaluating the bioaccessibility of uranium in contaminated mine soils
Bernd G Lottermoser
School of Earth Sciences, University of Tasmania, Private Bag 79, Hobart, Tasmania 7001, Australia
Sci Total Environ 409:3512-9. 2011..of bioaccessible uranium in the analysed soils and of uranium uptake into leaves and stems of the Sodom apple (Calotropis procera)...Molluscicidal activity of methomyl and cardenolide extracts from Calotropis procera and Adenium arabicum against the land snail Monacha cantiana
Ali Al-Sarar
Plant Protection Department, College of Food and Agriculture Sciences, King Saud University, P O Box 2460, Riyadh 11451, Saudi Arabia
Molecules 17:5310-8. 2012..the benzene (B) and methanol (M) extracts], one cardenolide extract from Calotropis procera (Aiton) W.T. Aiton (extract C), and methomyl against the harmful land snail Monacha cantiana (Montagu)...Evaluation of chemical constituents and free-radical scavenging activity of Swarnabhasma (gold ash), an ayurvedic drug
A Mitra
Department of Kayachikitsa, Institute of Post Graduate Ayurvedic Education and Research, Calcutta 700 009, India
J Ethnopharmacol 80:147-53. 2002..Ayurvedic pharmacy which consisted of Realger (As(2)S(2)), Lead oxide (Pb(3)O(4)), Pure gold (Au) and Latex of Calotropis gigantea...Disastrous results of indigenous methods of rabies prevention in developing countries
J K Dutta
Int J Infect Dis 6:236-7. 2002Insights on the phytochemical profile (cyclopeptides) and biological activities of Calotropis procera latex organic fractions
Thiago Lustosa Jucá
Departamento de Bioquimica e Biologia Molecular, Universidade Federal do Ceara, Av Humberto Monte, Campus do Pici, 60451 970 Fortaleza, CE, Brazil
ScientificWorldJournal 2013:615454. 2013b>Calotropis procera is a medicinal plant whose pharmacological properties are associated with its latex...Calotropis gigantiea (L.) R. Br (Apocynaceae): a phytochemical and pharmacological review
Madhuri Kadiyala
Department of Pharmacology, JSS College of Pharmacy, Udhagamandalam 643001, The Nilgiris, Tamil Nadu, India Electronic address
J Ethnopharmacol 150:32-50. 2013b>Calotropis gigantiea (L.) R...[Liposoluble constituents from the flowers of Calotropis gigantea and their antimicrobial activities]
Mao Yuan Wang
Tropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Sciences Key Laboratory of Crop Gene Resources and Germplasm Enhancement in Southern China, Danzhou 571737, China
Zhong Yao Cai 36:404-7. 2013To study the liposoluble constituents from the flowers of Calotropis gigantea and their antimicrobial activities.Development and characterization of new cell line BPH22 from midgut epithelial cells of Poekilocerus pictus (Fabricius, 1775)
Kiran R Kharat
Department of Zoology, Ket s V G Vaze College, Mulund, Mumbai, India
In Vitro Cell Dev Biol Anim 46:824-7. 2010Poekilocerus pictus is a painted grasshopper, which feeds on Calotropis sp. containing the cardiac glycosides. A new cell line BPH22 is developed from midgut of P. pictus to study its unique physiology and biochemistry...New insights into the complex mixture of latex cysteine peptidases in Calotropis procera
M V Ramos
Departamento de Bioquimica e Biologia Molecular, Universidade Federal do Ceara, Fortaleza, CE, Brazil
Int J Biol Macromol 58:211-9. 2013The latex of Calotropis procera is a rich source of proteolytic activity. This latex is known to contain two distinct cysteine peptidases: procerain and procerain B. In this study, new cysteine peptidases were purified from C...Effect of Cuscuta reflexa stem and Calotropis procera leaf extracts on glucose tolerance in glucose-induced hyperglycemic rats and mice
Mohammed Rahmatullah
Department of Biotechnology and Genetic Engineering, University of Development Alternative, Dhanmondi R A, Dhaka 1205, Bangladesh
Afr J Tradit Complement Altern Med 7:109-12. 2010Cuscuta reflexa (whole plant) and Calotropis procera (leaves) are used in folk medicine of Bangladesh to control blood sugar in patients suffering from diabetes mellitus...Isolation and characterization of some phytochemicals from Indian traditional plants
Neeharika Srivastava
Department of Biochemistry, Faculty of Science, University of Allahabad, Allahabad 211002, India
Biotechnol Res Int 2012:549850. 2012..antioxidants activities in aqueous extracts of different parts of some plants; Argemone mexicana, Datura metel, Calotropis procera, Thevetia peruviana, and Cannabis sativa...Identification of a novel Calotropis procera protein that can suppress tumor growth in breast cancer through the suppression of NF-κB pathway
Ramar Perumal Samy
Infectious Diseases Programme, Department of Microbiology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Singapore, Singapore
PLoS ONE 7:e48514. 2012..In the present study, we investigated the in vitro and in vivo antitumor activities of a novel Calotropis procera protein (CP-P) isolated from root bark...Insights from the predicted interactions of plant derived compounds to the gluco-corticoid receptor as an alternative to dexa-methasone
Rajeev Sarmah
Centre for Bioinformatics Studies, Dibrugarh University, Dibrugarh 786004, Assam India
Bioinformation 8:963-9. 2012..Therefore, alternative for DEX - plant metabolites of Calotropis sp and Swertia chirata were screened using docking appraoch...Pilot Study with regard to the Wound Healing Activity of Protein from Calotropis procera (Ait.) R. Br
Ramar Perumal Samy
Infectious Diseases Programme, Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597
Evid Based Complement Alternat Med 2012:294528. 2012We provide the scientific basis for the use of Calotropis procera for treating skin and wound infections in traditional medicine. The aqueous extract of stem-bark of C. procera exhibited more pronounced potent antimicrobial activity...Acaricidal activity of synthesized titanium dioxide nanoparticles using Calotropis gigantea against Rhipicephalus microplus and Haemaphysalis bispinosa
Sampath Marimuthu
Unit of Nanotechnology and Bioactive Natural Products, Post Graduate and Research Department of Zoology, C Abdul Hakeem College, Melvisharam 632 509, Vellore District, Tamil Nadu, India
Asian Pac J Trop Med 6:682-8. 2013..the acaricidal activity of titanium dioxide nanoparticles (TiO2 NPs) synthesized from flower aqueous extract of Calotropis gigantea(C. gigantea) against the larvae of Rhipicephalus (Boophilus) microplus [R. (B...Anticonvulsant action of Calotropis procera latex proteins
Raquel Cristina de Sousa Lima
Instituto Superior de Biomedicina Universidade Estadual do Ceará, Ceara, Brazil
Epilepsy Behav 23:123-6. 2012b>Calotropis procera (Ait.) R.Br. is a laticiferous plant belonging to the Apocynaceae family. C...Nature vs. nurture: gold perpetuates "stemness"
Willi Paul
Division of Biosurface Technology, Biomedical Technology Wing Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram 695012, India
J Stem Cells 6:181-98. 2011..Particulate-gold induced upregulation of FGFR1 and IGF2 expression, and decrease in IGF1 secretion indicates IGF1/2 mediated support for enhanced pluripotency and self-renewal in hESCs...Crystallization and X-ray diffraction analysis of an antifungal laticifer protein
Frederico Bruno-Moreno
Centro de Ciencias da Saude, Universidade de Fortaleza, Avenida Washington Soares 1321, Bairro Edson Queiroz, 60811 905 Fortaleza CE, Brazil
Acta Crystallogr Sect F Struct Biol Cryst Commun 69:646-9. 2013An osmotin (CpOsm) from the latex of Calotropis procera has been crystallized in both tetragonal and trigonal forms suitable for structure determination...In-vitro schizonticidal screening of Calotropis procera
P Sharma
School of Environmental Sciences, Jawaharlal Nehru University, New Delhi 110067, India
Fitoterapia 71:77-9. 2000Following an ethnobotanical approach, the ethanol extracts of Calotropis procera leaves, stems, roots, flowers and buds have been screened in vitro for antimalarial activity against chloroquine (CQ)-sensitive and CQ-resistant Plasmodium ..Genetic diversity in some perennial plant species with-in short distances
S C Pandeya
Flat No 202, Jhavar Estate, Thatipur, Gwalior 474 011, India
J Environ Biol 28:83-6. 2007..Delonix regia (Boj.) Refin., Cassia fistula L. and Calotropis procera R. Br...Wound healing in diabetes mellitus: traditional treatment modalities
A A Laitiff
Department of Anatomy, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia
Clin Ter 161:359-64. 2010..Such traditional plants are Aloe vera, Calotropis procera, Portulaca oleracea, Acalypha langiana, Plagiochasma appendiculatum and Momordica charantia...Evaluation of antipyretic activity of Calotropis gigantea (Asclepiadaceae) in experimental animals
H R Chitme
Institute of Pharmacy, Bundelkhand University, Jhansi 284128, U P, India
Phytother Res 19:454-6. 2005The roots of Calotropis gigantea have been used in leprosy, eczema, syphilis, elephantiasis, ulceration and cough in the Indian system of traditional medicine...