Genomes and Genes
Summary: Those biological processes that are involved in the transmission of hereditary traits from one organism to another.
Publications202 found, 100 shown here
- Propylnitrosourea-induced T-lymphomas in LEXF RI strains of rats: genetic analysisL M Lu
Department of Pathology and Biology of Disease, Graduate School of Medicine, Kyoto University, Japan
Br J Cancer 80:855-61. 1999..These observations indicate that PNU-induced lymphomagenesis is a multifactorial genetic process involving a number of loci linked with susceptibility and resistance...
- Phylogeography of the Solanaceae-infecting Basidiomycota fungus Rhizoctonia solani AG-3 based on sequence analysis of two nuclear DNA lociPaulo C Ceresini
ETH Zurich Swiss Federal Institute of Technology, IBZ, Universitaetstrasse 2, LFW B28, 8092 Zurich, Switzerland
BMC Evol Biol 7:163. 2007..solani AG-3 on potato and tobacco are shaped by population genetic processes. In this study, two field populations of R...
- Resilience in the aftermath of terrorism and during warzone exposure: Is it religiousness or is it number of blood relatives?H Stefan Bracha
J Clin Psychiatry 67:1156; author reply 1156-7. 2006
- Teaching molecular genetics: Chapter 1--Background principles and methods of molecular biologyNine V A M Knoers
Department of Human Genetics, University Medical Centre Nijmegen, P O Box 9101, 6500 HB Nijmegen, The Netherlands
Pediatr Nephrol 21:169-76. 2006..In addition, several basic and frequently used general molecular tools, such as restriction enzymes, Southern blotting, DNA amplification and sequencing are discussed, in order to lay the foundations for the forthcoming chapters...
- An introduction to genetics. The first article in a series about the significance of genetic science for Catholic health careJeffrey G Shaw
Cancer Center, Penrose St Francis Health Services, Colorado Springs, CO, USA
Health Prog 86:46-52. 2005
- Generalist genes and cognitive neuroscienceLee M Butcher
Social, Genetic and Developmental Psychiatry Centre, Number P080, Institute of Psychiatry, DeCrespigny Park, London, SE5 8AF, United Kingdom
Curr Opin Neurobiol 16:145-51. 2006....
- Roles for nutrients in epigenetic eventsAnna M Oommen
Department of Nutrition and Health Sciences, University of Nebraska at Lincoln, Lincoln, NE 68583 0806, USA
J Nutr Biochem 16:74-7. 2005....
- Proteome analysis of Halobacterium sp. NRC-1 facilitated by the biomodule analysis tool BMSorterRueichi R Gan
Institute of Biochemistry, National Yang Ming University, Taipei City Hospital, Taipei 112, Taiwan, Republic of China
Mol Cell Proteomics 5:987-97. 2006..Thus this study demonstrated that proteome analysis can provide useful information and help systems analyses of organisms...
- Poly(ADP-ribose). The most elaborate metabolite of NAD+Alexander Burkle
Department of Biology, University of Konstanz, Germany
FEBS J 272:4576-89. 2005..In this article, the most recent advances in this rapidly growing field are summarized...
- Basic geneticsBruce R Korf
Department of Genetics, University of Alabama at Birmingham, 1530 3rd Avenue, South Kaul 230, Birmingham, AL 35294, USA
Prim Care 31:461-78, vii. 2004..Definitions of terms that appear here in italics can be found in the on-line, illustrated glossary at www.genetests.org...
- Mutual benefit can promote the evolution of preferential interactions and in this way can lead to the evolution of true altruismLaureano Castro
Departamento de Mejora Genética Animal, SGIT INIA, Carretera de la Coruña Km 7, Madrid 28040, Spain
Theor Popul Biol 65:239-47. 2004..This requires that the tag used in the election of partners is the altruistic or selfish behaviour itself...
- SIR repression of a yeast heat shock gene: UAS and TATA footprints persist within heterochromatinE A Sekinger
Department of Biochemistry and Molecular Biology, Louisiana State University Medical Center, Shreveport, LA 71130 3932, USA
EMBO J 18:7041-55. 1999..it is unclear how this structure blocks transcription while remaining fully permissive to other genetic processes such as recombination or integration...
- Enzymatic DNA methylation is an epigenetic control for genetic functions of the cellB F Vanyushin
Belozersky Institute of Physico Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia
Biochemistry (Mosc) 70:488-99. 2005..DNA methylation controls all genetic processes in the cell (replication, transcription, DNA repair, recombination, gene transposition) and it is a ..
- Molecular signatures of N-nitroso compounds in Caco-2 cells: implications for colon carcinogenesisDennie G A J Hebels
Department of Health Risk Analysis and Toxicology, Maastricht University, 6200 MD Maastricht, The Netherlands
Toxicol Sci 108:290-300. 2009..is an important route of exposure through endogenous nitrosation, we hypothesize that NOC exposure targets genetic processes relevant in colon carcinogenesis...
- Genetic expression by fetal chorionic villi during the first trimester of human gestationD S Dizon Townson
Departments of Obstetrics and Gynecology and Human Genetics, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
Am J Obstet Gynecol 183:706-11. 2000..sequence of events that consists of cellular adhesion and limited invasion controlled by relatively unknown genetic processes. We hypothesized that genes expressed by first-trimester chorionic villi constitute critical regulators of ..
- GeneMesh: a web-based microarray analysis tool for relating differentially expressed genes to MeSH termsSaurin D Jani
Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC 29425, USA
BMC Bioinformatics 11:166. 2010....
- Limbs in whales and limblessness in other vertebrates: mechanisms of evolutionary and developmental transformation and lossLars Bejder
Department of Biology, Dalhousie University, Halifax, Nova Scotia, Canada B3H 4J1
Evol Dev 4:445-58. 2002..Selective pressures acting on a wide range of developmental processes and adult traits other than the limbs are likely to have driven the loss of hindlimbs in whales...
- SOX9 is not required for the cellular events of testicular organogenesis in XX mole ovotestesF David Carmona
Departamento de Genética e Instituto de Biotecnología, Facultad de Ciencias, Universidad de Granada, Granada, Spain
J Exp Zool B Mol Dev Evol 312:734-48. 2009..The fact that FST remains inactive during the critical stages of female gonad development, explains the lack of migration inhibition, and may be a consequence of improper WNT4 signalling in the mole...
- An investigation of the molecular basis of the spontaneous occurrence of a catalase-negative phenotype in Helicobacter pyloriJ Manos
School of Microbiology and Immunology, University of New South Wales, Sydney, Australia
Helicobacter 3:28-38. 1998..pylori (UNSW-RU1) and sequenced katA in the parent strain and the promoters of both phenotypes as a prelude to understanding the genetic processes leading to the failure to express catalase.
- Structure, dynamics, and branch migration of a DNA Holliday junction: a single-molecule fluorescence and modeling studyMikhail A Karymov
Department of Pharmaceutical Sciences, University of Nebraska Medical Center, 986025 Nebraska Medical Center, Omaha, Nebraska 68198 6025, USA
Biophys J 95:4372-83. 2008The Holliday junction (HJ) is a central intermediate of various genetic processes, including homologous and site-specific DNA recombination and DNA replication...
- DNA polymorphism in recombining and non-recombining mating-type-specific loci of the smut fungus MicrobotryumA A Votintseva
Department of Plant Sciences, University of Oxford, Oxford, UK
Heredity (Edinb) 106:936-44. 2011The population-genetic processes leading to the genetic degeneration of non-recombining regions have mainly been studied in animal and plant sex chromosomes...
- [Aging and carcinogenesis]V N Anisimov
Department of Carcinogenesis and Oncogerontology, N N Petrov Research Institute of Oncology, Pesochny 2, St Petersburg 197758
Adv Gerontol 10:99-125. 2002..Some common genetic processes (e.g...
- Genome-wide mutagenesis of Xanthomonas axonopodis pv. citri reveals novel genetic determinants and regulation mechanisms of biofilm formationJinyun Li
Department of Microbiology and Cell Science, Citrus Research and Education Center, University of Florida, Lake Alfred, Florida, United States of America
PLoS ONE 6:e21804. 2011..This work is the first report on a genome-wide scale of the genetic processes of biofilm formation in plant pathogenic bacteria...
- Putative DEAD and DExH-box RNA helicases families in Entamoeba histolyticaLaurence A Marchat
ENMH IPN, Programa Institucional de Biomedicina Molecular, Mexico DF, Mexico
Gene 424:1-10. 2008RNA helicases catalyze the unwinding of double-stranded RNA structures to perform numerous genetic processes. These enzymes are characterized by the presence of a conserved helicase domain with specific helicases motifs whose amino acid ..
- The MAP kinase TVK1 regulates conidiation, hydrophobicity and the expression of genes encoding cell wall proteins in the fungus Trichoderma virensArtemio Mendoza-Mendoza
Laboratorio Nacional de Genómica para la Biodiversidad, Centro de Investigacion y de Estudios Avanzados, Campus Guanajuato, Apartado Postal 629, 36500, Irapuato, Guanajuato, Mexico
Microbiology 153:2137-47. 2007Mitogen-activated protein (MAP) kinases modulate morphological and genetic processes, which determine cell fate...
- The imprecision of heterozygosity-fitness correlations hinders the detection of inbreeding and inbreeding depression in a threatened speciesCatherine E Grueber
Department of Zoology, University of Otago, Dunedin 9054, New Zealand
Mol Ecol 20:67-79. 2011..area has been performed on generally outbred, nonbottlenecked populations, but differences in population genetic processes may limit extrapolation of results to threatened populations...
- Dominant male sterility in sorghum: effect of nuclear background on inheritance of tissue-culture-induced mutationLev A Elkonin
Agricultural Research Institute for South East Region of Russia, 410010 Saratov, Russia
Theor Appl Genet 111:1377-84. 2005Occurrence of genetic instability and formation of stable mutations are basic genetic processes. This study demonstrates that nuclear background may influence the formation of stable dominant nuclear gene of male sterility (MS) on the ..
- Effect of single-strand break on branch migration and folding dynamics of Holliday junctionsDmytro Palets
Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, Nebraska, USA
Biophys J 99:1916-24. 2010..or four-way junction, is a central intermediate state of DNA for homologous genetic recombination and other genetic processes such as replication and repair...
- Glucuronidation in humans. Pharmacogenetic and developmental aspectsS N de Wildt
Department of Pediatrics, Erasmus University and University Hospital, Rotterdam, The Netherlands
Clin Pharmacokinet 36:439-52. 1999..of drug clearance is metabolism, something that is not only determined by ontogenic regulation but also by genetic processes which add to the variability of drug metabolism during different stages of childhood...
- Effects of population succession on demographic and genetic processes: predictions and tests in the daylily Hemerocallis thunbergii (Liliaceae)Mi Yoon Chung
Department of Biology and Institute of Basic Science, Gyeongsang National University, Jinju 660 701, South Korea
Mol Ecol 16:2816-29. 2007..thunbergii populations across the landscape. This variation is generally consistent with succession-stage-specific differences in ecological processes operating within these populations...
- [Testing antineoplastic activity of new platinum(II) and palladium(II) complex compounds]Katarzyna Malinowska
Uniwersytet Medyczny w Lodzi, Wydział Fizjoterapii, Zakład Chemii i Biochemii Klinicznej, Katedra Chemii i Biochemii Klinicznej
Pol Merkur Lekarski 26:57-61. 2009A pyrazole system is incorporated in many biological molecules which play an important part in genetic processes. It seems that co-ordinating biological molecules, which would serve as carriers, should contribute to minimising the toxic ..
- 'DEAD-box' helicase from Plasmodium falciparum is active at wide pH and is schizont stage-specificArun Pradhan
Malaria Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India
J Vector Borne Dis 44:12-22. 2007DNA helicases catalyse unwinding of duplex DNA in an ATP-dependent manner and are involved in all the basic genetic processes. In order to study these important enzymes in the human malaria parasite we have recently cloned the first full-..
- Catalytic inhibitors of DNA topoisomerase IIT Andoh
Department of Bioengineering, Faculty of Engineering, Soka University, 1 236 Tangi cho, Hachioji, Tokyo 192 0003, Japan
Biochim Biophys Acta 1400:155-71. 1998..These compounds target the enzyme within the cell and inhibit various genetic processes involving the enzyme, such as DNA replication and chromosome dynamics, and thus proved to be good probes for ..
- The molecular biology of recombination in Mycobacteria: what do we know and how can we use it?D G Niranjala Muttucumaru
Centre for Infectious Disease, Institute for Cell and Molecular Science, Barts and The London, Queen Mary s School of Medicine and Dentistry, Turner Street, London, E1 2AD, UK
Curr Issues Mol Biol 6:145-57. 2004..A recently developed method for studying essential genes will generate further insights into the biology of these important organisms...
- Heterozygosity-fitness correlations among wild populations of European tree frog (Hyla arborea) detect fixation loadE Luquet
Universite Lyon 1, CNRS UMR 5023 Ecologie des Hydrosystèmes Fluviaux, Universite Claude Bernard Lyon 1, Universite de Lyon, 43 Bd du 11 Novembre 1918, 69622 Villeurbanne Cedex, France
Mol Ecol 20:1877-87. 2011..depression within populations and sometimes at the population level but without consideration about the genetic processes measured...
- Single molecule fluorescence analysis of branch migration of holliday junctions: effect of DNA sequenceMikhail A Karymov
Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Nebraska Medical Center, Omaha, Nebraska 68198 6025, USA
Biophys J 95:1239-47. 2008The Holliday junction is a central intermediate in various genetic processes including homologous, site-specific recombination and DNA replication...
- Weak founder effect signal in a recent introduction of Caribbean AnolisJ Eales
Environment Centre for Wales, School of Biological Sciences, College of Natural Sciences, Bangor University, Gwynedd LL57 2UW, UK
Mol Ecol 17:1416-26. 2008Species introductions provide a rare opportunity to study rapid evolutionary and genetic processes in natural systems, often under novel environmental pressures...
- Pedigree parablesR L Bennett
Division of Medical Genetics, University of Washington, Seattle 98195 7720, USA
Clin Genet 58:241-9. 2000..At what point do such practices hinder the recognition of genetic processes? Is there evidence that harm has occurred to subjects who have appeared in published pedigrees? How does the ..
- Maize as a model for the evolution of plant nuclear genomesB S Gaut
Department of Ecology and Evolutionary Biology, University of California, Irvine, CA 92697 2525, USA
Proc Natl Acad Sci U S A 97:7008-15. 2000..Population genetic processes also affect the evolution of genomes...
- Genetic structures of copy number variants revealed by genotyping single spermMinjie Luo
Department of Molecular Genetics, Microbiology, and Immunology The Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, New Jersey, United States of America
PLoS ONE 4:e5236. 2009..However, because of the presence of their multiple copies, variability in copy numbers and the diploidy of the human genome, detailed genetic structure of CNVs cannot be readily studied by available techniques...
- Mass extinctions, biodiversity explosions and ecological nichesAlain Pavé
Laboratoire de biométrie et de biologie évolutive, UMR CNRS 5558, Universite Claude Bernard, Lyon 1, 69622 Villeurbanne, France
C R Biol 325:755-65. 2002..of ecological relationships, such as 'niche-sharing', which involves coexistence or cooperation), even if genetic processes must also be involved...
- Maximum likelihood estimates of species trees: how accuracy of phylogenetic inference depends upon the divergence history and sampling designJohn E McCormack
Department of Ecology and Evolutionary Biology, and the Museum of Zoology, University of Michigan, Ann Arbor, MI 48109 1079, USA
Syst Biol 58:501-8. 2009..trees that contain them has led researchers to methods that incorporate the inherent stochasticity of genetic processes in the phylogenetic estimation procedure...
- Phylogeographic history of grey wolves in EuropeMałgorzata Pilot
Museum and Institute of Zoology, Polish Academy of Sciences, 00 679 Warszawa, Poland
BMC Evol Biol 10:104. 2010..patterns of intra-specific genetic differentiation are substantially affected by glacial history, population genetic processes occurring during Pleistocene glaciations are still poorly understood...
- Colon Cancer Family Registry: an international resource for studies of the genetic epidemiology of colon cancerPolly A Newcomb
Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 16:2331-43. 2007..Family studies have served as a cornerstone of genetic research on colorectal cancer...
- Regulation of secondary metabolism by chromatin structure and epigenetic codesJoseph Strauss
Fungal Genetics and Genomics Unit, AIT Austrian Institute of Technology and BOKU University Vienna, Muthgasse 18, A 1190 Vienna, Austria
Fungal Genet Biol 48:62-9. 2011Chromatin, composed of DNA wrapped around an octamer of histones, is the relevant substrate for all genetic processes in eukaryotic nuclei...
- Mechanisms causing rapid and parallel losses of ribose catabolism in evolving populations of Escherichia coli BV S Cooper
Center for Microbial Ecology, Michigan State University, East Lansing, Michigan 48824, USA
J Bacteriol 183:2834-41. 2001..We sought to identify the population genetic processes and molecular genetic events that caused these rapid and parallel losses...
- Interactions of protein complexes on supercoiled DNA: the mechanism of selective synapsis by Tn3 resolvaseJ Lesley Brown
Institute of Biomedical and Life Sciences, University of Glasgow, 56 Dumbarton Road, Glasgow G11 6NU, Scotland, UK
J Mol Biol 319:371-83. 2002..interactions of distant sites on DNA molecules, mediated by DNA-binding proteins, feature in many regulated genetic processes. We used plasmids containing up to six res recombination sites for Tn3 resolvase to analyse looping ..
- Embryonic and larval development of the Drosophila mushroom bodies: concentric layer subdivisions and the role of fasciclin IIMitsuhiko Kurusu
Institute of Biological Sciences, and Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba 305 8572, Japan
Development 129:409-19. 2002..In order to understand the cellular and genetic processes that control the early development of MBs, we have performed high-resolution neuroanatomical studies of the ..
- Analysis of gene expression in response to water deficit of chickpea (Cicer arietinum L.) varieties differing in drought toleranceDeepti Jain
National Institute of Plant Genome Research, Aruna Asaf Ali Marg, New Delhi 110067, India
BMC Plant Biol 10:24. 2010..cultivated chickpea has a high morphological but narrow genetic diversity, and understanding the genetic processes of this plant is hindered by the fact that the chickpea genome has not yet been sequenced and its EST ..
- A human-derived reporter gene for noninvasive imaging in humans: mitochondrial thymidine kinase type 2Vladimir Ponomarev
Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
J Nucl Med 48:819-26. 2007A human-derived intrinsically nonimmunogenic reporter gene was tested for PET imaging of different molecular-genetic processes for potential clinical use.
- Abscisic acid-mediated epigenetic processes in plant development and stress responsesViswanathan Chinnusamy
Water Technology Centre, Indian Agricultural Research Institute, New Delhi, India
J Integr Plant Biol 50:1187-95. 2008..Although ABA-regulated genetic processes are well known, recent discoveries reveal that epigenetic processes are an integral part of ABA-regulated ..
- Disentangling the effects of evolutionary, demographic, and environmental factors influencing genetic structure of natural populations: Atlantic herring as a case studyOscar E Gaggiotti
Laboratoire d Ecologie Alpine, UMR CNRS 5553, Universite Joseph Fourier, 38041 Grenoble, France
Evolution 63:2939-51. 2009..Using a combination of such methods, we examined the roles of environment (i.e., natural selection), random genetic processes (i.e., drift), and demography and life histories (e.g...
- Integrating coalescent and ecological niche modeling in comparative phylogeographyBryan C Carstens
Department of Ecology and Evolutionary Biology, Museum of Zoology, University of Michigan, Ann Arbor, MI 48109 1079, USA
Evolution 61:1439-54. 2007..phylogeographic research, but achieving this goal can be complicated by the stochastic variance inherent to genetic processes. Statistical approaches to testing phylogeographic hypotheses accommodate this stochasticity by evaluating ..
- Language as shaped by the brainMorten H Christiansen
Department of Psychology, Cornell University, Ithaca, NY 14853, USA
Behav Brain Sci 31:489-508; discussion 509-58. 2008..UG have evolved? We argue that UG could not have arisen either by biological adaptation or non-adaptationist genetic processes, resulting in a logical problem of language evolution...
- [Genetic and epidemiological studies in Dagestan highland isolates]K B Bulaeva
Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 117809 Russia
Genetika 39:413-22. 2003..The relationship between these interpopulation differences and the genetic processes that have been occurring in the populations throughout their history has been demonstrated...
- The archaeal topoisomerase reverse gyrase is a helix-destabilizing protein that unwinds four-way DNA junctionsAnna Valenti
Institute of Protein Biochemistry, Consiglio Nazionale delle Ricerche, Via Pietro Castellino 111, 80131 Naples, Italy
J Biol Chem 285:36532-41. 2010..structures have important functional roles but may also severely interfere with DNA replication and other genetic processes; therefore, they are targeted by regulatory and architectural proteins, and dedicated pathways exist for ..
- Delimiting species without monophyletic gene treesL Lacey Knowles
Department of Ecology and Evolutionary Biology, Museum of Zoology, University of Michigan, Ann Arbor, MI 48109 1079, USA
Syst Biol 56:887-95. 2007..from when and how speciation occurred, and failure to take into account the high stochastic variance of genetic processes. Both the utility and sensitivities of the coalescent-based approach outlined here are discussed; most ..
- Antibody diversification by somatic mutation: from Burnet onwardsMichael S Neuberger
1Medical Research Council Laboratory of Molecular Biology, Cambridge, UK
Immunol Cell Biol 86:124-32. 2008..Work over the subsequent half-century substantiated Burnet's speculation, revealing two distinct novel genetic processes. During early development (when Burnet first thought the randomization took place) programmed gene segment ..
- Relevance of the deletion polymorphisms of the glutathione S-transferases GSTT1 and GSTM1 in pharmacology and toxicologyH M Bolt
Institut fur Arbeitsphysiologie an der Universitat Dortmund, Leibniz Research Centre for Working Environment and Human Factors, Dortmund, Germany
Curr Drug Metab 7:613-28. 2006..The structures of the GSTT and GSTM gene areas explain the underlying genetic processes. GSTT1-1 is highly conserved during evolution and plays a major role in phase-II biotransformation of a ..
- The intestinal epithelium and its neoplasms: genetic, cellular and tissue interactionsW F Dove
McArdle Laboratory for Cancer Research, University of Wisconsin, Madison 53706, USA
Philos Trans R Soc Lond B Biol Sci 353:915-23. 1998....
- HIV evolutionary dynamics within and among hostsPhilippe Lemey
Department of Zoology, University of Oxford, Oxford, UK
AIDS Rev 8:125-40. 2006..techniques have been developed to reconstruct the HIV evolutionary history and to investigate the population genetic processes that shape viral diversity...
- Cushing syndrome caused by adrenocortical tumors and hyperplasias (corticotropin- independent Cushing syndrome)Constantine A Stratakis
Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
Endocr Dev 13:117-32. 2008..adrenal disease and its pigmented variant, primary pigmented nodular adrenocortical disease are mostly genetic processes. Macronodular BAHs, ACTH-independent macronodular hyperplasia or massive macronodular adrenocortical disease ..
- DNA sequence-dependent variation in nucleosome structure, stability, and dynamics detected by a FRET-based analysisL Kelbauskas
Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA
Biochem Cell Biol 87:323-35. 2009..Nucleosomes restrict regulatory factor access to DNA, thereby impeding genetic processes. Eukaryotic cells possess mechanisms to alter nucleosome structure, to generate DNA access, but alterations ..
- The emergence of major cellular processes in evolutionC Ouzounis
AI Center, SRI International, Menlo Park, CA 94025 3493, USA
FEBS Lett 390:119-23. 1996..In addition, genetic processes such as translation are conserved and close to the original form...
- Dynamics of attitudes and genetic processesStephen J Guastello
Department of Psychology, Marquette University, Milwaukee, WI 53201 1881, USA
Nonlinear Dynamics Psychol Life Sci 12:75-86. 2008..The linear model projected a gradual and continuing bifurcation between authoritarians and non-authoritarians. The nonlinear model projected a stabilization of authoritarian attitudes...
- Comparing performance by parents and offspring on a rapid tapping taskChungGon Kim
School of Kinesiology University of Minnesota, Minneapolis, USA
Percept Mot Skills 101:605-12. 2005..This finding suggests that the potential of youngsters' future performance may be predicted with greater certainty by observing their parents' present performance. This may improve the predictive power of planned programs...
- Systems biology. Less is more in modeling large genetic networksStefan Bornholdt
Institute for Theoretical Physics, University of Bremen, Otto Hahn Allee, D 28359 Bremen, Germany
Science 310:449-51. 2005
- A proteome-wide approach identifies sumoylated substrate proteins in yeastVikram Govind Panse
Biochemie Zentrum der Universitat Heidelberg, Im Neuenheimer Feld 328, 69120 Heidelberg, Germany and Cellzome AG, Meyerhofstrasse 1, 69117 Heidelberg, Germany
J Biol Chem 279:41346-51. 2004..Thus, the identification of a broad range of SUMO-1 substrate proteins is expected to lead to further insight into the regulatory aspects of sumoylation...
- Cell cycle checkpoints -- molecular backgroundBarbara Grzelakowska-Sztabert
Nencki Institute of Experimental Biology, Warszawa, Poland
Folia Morphol (Warsz) 63:1-3. 2004..The paper provides basic information about the molecular mechanisms operating in various cell cycle checkpoints activated by DNA damage or disturbances in mitotic spindle assembly...
- Using the Unified Modelling Language (UML) to guide the systemic description of biological processes and systemsMagali Roux-Rouquié
BSMI, Institut Pasteur, 25 28 Rue du Dr Roux, 75724 Paris Cedex 15, France
Biosystems 75:3-14. 2004..This makes unambiguous representations of biological systems, which would be suitable for translation into mathematical and computational formalisms, enabling analysis, simulation and prediction of these systems behaviours...
- What's the differenceColin Berry
QJM 96:953-4. 2003
- Epigenetic landscape for initiation of DNA replicationVladimir V Sherstyuk
Russian Academy of Sciences, Siberian Branch, Institute of Cytology and Genetics, pr Akad Lavrentieva 10, Novosibirsk, 630090, Russia
Chromosoma 123:183-99. 2014..In the last few years, a number of different genome-wide studies have broadened the understanding of replication origin regulation. In this review, we discuss the epigenetic factors and mechanisms that modulate origin choice and firing. ..
- Corridors for migration between large subdivided populations, and the structured coalescentJohn Wakeley
Department of Organismic and Evolutionary Biology, Harvard University, 2102 Biological Laboratories, Cambridge, MA 02138, USA
Theor Popul Biol 70:412-20. 2006..This justifies the application of a modified structured coalescent to some hierarchically structured populations...
- Determining when contamination is pollution - weight of evidence determinations for sediments and effluentsPeter M Chapman
Golder Associates, 195 Pemberton Avenue, North Vancouver, BC, Canada V7P 2R4
Environ Int 33:492-501. 2007..Effectively, a WOE assessment comprises an initial screening-level ecological risk assessment (ERA), which may be followed by a detailed-level ERA if key uncertainties need to be resolved...
- Construction of a high-density composite map and comparative mapping of segregation distortion regions in barleyHaobing Li
Tasmanian Institute of Agricultural Research and School of Agricultural Science, University of Tasmania, Private Bag 54, Hobart, TAS, 7001, Australia
Mol Genet Genomics 284:319-31. 2010..Six of the seven centromeric regions harboured SDRs suggesting that genetic processes related to position near a centromere caused the segregation distortion in these SDRs...
- [Endometriosis]László Lampé
Debreceni Egyetem, Orvos és Egészségtudományi Centrum, Általános Orvostudományi Kar, Szülészeti és Nőgyógyászati Klinika, Debrecen
Orv Hetil 150:245-50. 2009..adenomyosis), retrograde menstruation, embolisation, metaplasia together with defective immunological and genetic processes have all been confirmed as possible mechanisms of the development of disease...
- A role for Snf2-related nucleosome-spacing enzymes in genome-wide nucleosome organizationTriantaffyllos Gkikopoulos
Wellcome Trust Centre for Gene Regulation and Expression, College of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK
Science 333:1758-60. 2011..This organization is likely to influence many genetic processes, requiring access to the underlying DNA...
- How DNA coiling enhances target localization by proteinsB van den Broek
Department of Physics and Astronomy, Faculty of Sciences, Vrije Universiteit, De Boelelaan 1081, 1081 HV Amsterdam, The Netherlands
Proc Natl Acad Sci U S A 105:15738-42. 2008Many genetic processes depend on proteins interacting with specific sequences on DNA. Despite the large excess of nonspecific DNA in the cell, proteins can locate their targets rapidly...
- Colored petri nets to model gene mutation and amino acids classificationJinliang Yang
School of Control Science and Engineering, Shandong University, Jinan, Shandong Province 250061, China
J Theor Biol 300:183-92. 2012..Choosing an appropriate model for processing these codons is a useful method to study genetic processes in Molecular Biology...
- Molecular biology of sporadic gastric cancer: prognostic indicators and novel therapeutic approachesMario Scartozzi
Clinica di Oncologia Medica, Università Politecnica delle Marche Azienda Ospedaliera Umberto I, Ancona, Italy
Cancer Treat Rev 30:451-9. 2004..e., thymidilate synthase that is targeted by 5FU) or to a new class of antineoplastic molecules (i.e., c-erb B-2 targeted by trastuzumab, COX-2 by NSAIDs, matrix metalloproteinases, EGFR and VEGFR by specific inhibitors)...
- Functional imaging techniques for evaluation of sarcomasRodney J Hicks
The Centre for Molecular Imaging, The Peter MacCallum Cancer Centre, Melbourne, Australia
Cancer Imaging 5:58-65. 2005..This heterogeneity reflects physiologic, biochemical and genetic processes that are amenable to characterisation by functional imaging...
- Seed-mediated connectivity among fragmented populations of Quercus castanea (Fagaceae) in a Mexican landscapeM Luisa Herrera-Arroyo
Centro de Investigaciones en Ecosistemas Universidad Nacional Autónoma de México UNAM, Antigua Carretera a Pátzcuaro No 8701, Col Ex Hacienda San José de la Huerta, Morelia 58190 Michoacán, Mexico
Am J Bot 100:1663-71. 2013..may create loss of connectivity among tree populations and constitutes a serious threat to ecological and genetic processes. We tested the central hypothesis that seed dispersal mitigates the impact of fragmentation by comparing ..
- CAVEman: Standardized anatomical context for biomedical data mappingAndrei L Turinsky
Sun Center of Excellence for Visual Genomics, University of Calgary, Calgary, Alberta, Canada
Anat Sci Educ 1:10-8. 2008..The CAVEman system is now used to visualize genetic processes in the context of the human anatomy and to facilitate visual exploration of the data...
- Chronic cocaine causes long-term alterations in circadian period and photic entrainment in the mouseA C Stowie
Department of Biological Sciences, Kent State University, Kent, OH 44242, USA
Neuroscience 284:171-9. 2015The disruptive effects of cocaine on physiological, behavioral and genetic processes are well established...
- An overview of the utility of population simulation software in molecular ecologySean Hoban
National Institute for Mathematical and Biological Synthesis, University of Tennessee, 1122 Volunteer Blvd, Suite 110A Knoxville, TN, 37996 3410, USA
Mol Ecol 23:2383-401. 2014..demographic-genetic simulation software, especially with respect to individual life history, landscapes and genetic processes, are transforming and expanding the ways that molecular data can be used...
- MtDNA ancestry of Rio de Janeiro population, BrazilSuellen Bernardo
Laboratório de Diagnósticos por DNA, Instituto de Biologia, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil
Mol Biol Rep 41:1945-50. 2014..The high proportion of African mtDNA lineages in the population of Rio de Janeiro is in accordance with studies related to other Brazilian states...
- The emerging roles of eRNAs in transcriptional regulatory networksKambiz Mousavi
Moderna Therapeutics Inc Cambridge, MA USA
RNA Biol 11:106-10. 2014..Critical to our understanding of genetic processes is the mechanism by which ncRNAs exert their roles...
- Population-genetic influences on genomic estimates of the inbreeding coefficient: a global perspectiveTrevor J Pemberton
Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Man, Canada
Hum Hered 77:37-48. 2014Culturally driven marital practices provide a key instance of an interaction between social and genetic processes in shaping patterns of human genetic variation, producing, for example, increased identity by descent through ..
- Cytoplasmic localization and reorganization in ascidian eggs: role of postplasmic/PEM RNAs in axis formation and fate determinationKazuhiro W Makabe
Institute of Socio Arts and Sciences, University of Tokushima, Tokushima, Japan
Wiley Interdiscip Rev Dev Biol 1:501-18. 2012..eggs and embryos and cytoplasmic movements to relocalize them are fundamental for the orderly cellular and genetic processes during early embryogenesis...
- The elusive object of desire--interactions of bacteriophages and their hostsSergei Nechaev
Laboratory of Molecular Carcinogenesis, NIEHS NIH, Room D434, 111 Alexander Dr, Research Triangle Park, NC 27709, USA
Curr Opin Microbiol 11:186-93. 2008..As a result, phages play central roles in a great variety of genetic processes and increase the rate of evolutionary change of the bacterial host, which could ultimately work to the ..
- Induced mutations in yeast cell populations adapting to an unforeseen challengeLindsay S Moore
Department of Physics and Network Biology Research Laboratories, Technion Israel Institute of Technology, Haifa, Israel
PLoS ONE 9:e111133. 2014..Our results demonstrate the existence of adaptation mechanisms beyond random mutation, suggesting a tight connection between physiological and genetic processes.
- Large-scale chromatin remodeling at the immunoglobulin heavy chain locus: a paradigm for multigene regulationDaniel J Bolland
Laboratory of Chromatin and Gene Expression, Babraham Institute, Babraham Research Campus, Cambridge, UK
Adv Exp Med Biol 650:59-72. 2009..the largest multigene loci in the mammalian genome and V(D)J recombination is one of the most complicated genetic processes in the nucleus...
- Targeted therapy in GIST: in silico modeling for prediction of resistanceMarco A Pierotti
Fondazione IRCCS Istituto Nazionale dei Tumori Milano, Via Venezian 1, 20133 Milano, Italy
Nat Rev Clin Oncol 8:161-70. 2011Elucidation of the genetic processes leading to neoplastic transformation has identified cancer-promoting molecular alterations that can be selectively targeted by rationally designed therapeutic agents...
- Mass fluctuation kinetics: analysis and computation of equilibria and local dynamicsP Azunre
Massachusetts Institute of Technology, EECS Department, Room 13 3029, Cambridge, USA
IET Syst Biol 5:325-35. 2011..Moreover, our analysis provides evidence that decreasing volume from the MAK regime (infinite volume) has a destabilising effect on system dynamics...
- The need for a behavioural science focus in research on mental health and mental disordersHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Center for Clinical Epidemiology and Longitudinal Studies CELOS, Technische Universitat Dresden, Dresden, Germany
Int J Methods Psychiatr Res 23:28-40. 2014..result of developmental dysfunctions of psychological functions and processes as well as neurobiological and genetic processes that interact with the environment...
- Effects of genomic imprinting on quantitative traitsHamish G Spencer
National Research Centre for Growth and Development and Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, P O Box 56, Dunedin, 9054, New Zealand
Genetica 136:285-93. 2009Standard Mendelian genetic processes incorporate several symmetries, one of which is that the level of expression of a gene inherited from an organism's mother is identical to the level should that gene have been inherited paternally...
- Genomics and autism spectrum disorderNorah L Johnson
Marquette University College of Nursing, Milwaukee, WI 53201, USA
J Nurs Scholarsh 45:69-78. 2013....
- Effects of genetic drift and gene flow on the selective maintenance of genetic variationBastiaan Star
Centre for Ecological and Evolutionary Synthesis CEES, Department of Biosciences, University of Oslo, N 0316 Oslo, Norway
Genetics 194:235-44. 2013..for the genetic variation ubiquitous in natural populations are often classified by the population-genetic processes they emphasize: natural selection or mutation and genetic drift...
- Intraclonal heterogeneity in concomitant monoclonal lymphocyte and plasma cell populations: combining flow cytometric cell sorting with molecular monoclonality profilingBarbara K Zehentner
HematoLogics, Inc, Seattle, WA, USA
Clin Lymphoma Myeloma Leuk 13:214-7. 2013..Our findings demonstrated that related genetic processes are less likely than unrelated genetic processes...
- From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade laterValerie Barbe
CEA, Institut de Génomique, Genoscope, 2 rue Gaston Cremieux, 91057 Evry, France
Microbiology 155:1758-75. 2009..subtilis is an epiphyte). This should permit investigators to make reliable inferences to prepare validation experiments in a variety of domains of bacterial growth and development as well as build up accurate phylogenies...
- Human development: biological and genetic processesIrving I Gottesman
Department of Psychiatry and Department of Psychology, University of Minnesota, Minneapolis, MN 55454, USA
Annu Rev Psychol 56:263-86. 2005..For human behavioral disorders such as schizophrenia and autism, the inherent plasticity of the nervous system requires a systems approach to incorporate all of the myriad epigenetic factors that can influence such outcomes...
- Mechanisms for the evolution of novel DNA specificity in a transcription factor fJoseph W Thornton; Fiscal Year: 2013..The resulting structure-function knowledge will facilitate efforts to engineer TFs with new DNA-binding specificities in synthetic biology and biomedicine. ..
- PHENOGENETICS OF SKULL AND BRAIN INTEGRATION IN CRANIOSYNOSTOSISJOAN THERESE RICHTSMEIER; Fiscal Year: 2012..Ours is a "phenogenetic" approach that attempts to connect biological phenotypes with their underlying genetic processes such as regional differentiation by activation of signaling...
- Poly ADP-ribose Polymerase in Chromatin and Transcriptional RegulationAlexei V Tulin; Fiscal Year: 2012..Statement: Understanding how an organism can utilize PARP protein ability to modulate chromatin and transcription will provide fundamental insight into genetic processes that are essential for growth, development, and pathogenesis.
- Nicotine Addiction: Learning, Neural &Genetic ProcessThomas J Gould; Fiscal Year: 2013....
- Genomic Patterns of Polymorphism in PrimatesJeffrey D Wall; Fiscal Year: 2012..A major goal is to infer the relative influence of a number of population genetic processes that differentially affect the X chromosome versus autosomes, such as changes in population size and sex-..
- Summer Undergraduate Research Program in Molecular and Developmental NeurobiologyMladen Roko Rasin; Fiscal Year: 2013..The multidisciplinary research focus of the other faculty mentors on the cellular, molecular, and genetic processes underlying developmental and degeneration of the nervous system also has implications for the etiology, ..
- MODELS OF COMPLEX GENETIC SYSTEMSMONTGOMERY WILSON SLATKIN; Fiscal Year: 2012..research will be intended to help analyze and interpret DNA sequence data both for understanding basic genetic processes such as natural selection and recombination and for understanding the history of humans and the genetic ..
- Program on Molecular and Cellular Mechanisms of TumorigenesisJef D Boeke; Fiscal Year: 2010..to an understanding of the molecular mechanisms responsible for cancer by investigating fundamental genetic processes involved in the control of cell growth and the maintenance of genomic stability...
- RESTMD-CHARMM simulation of the Chk2/PP2A interaction in DNA repairSHANADEEN C BEGAY; Fiscal Year: 2011..This research will advance cancer care by providing unprecedented insights into the fundamental genetic processes and determinants of breast cancer susceptibility.
- Fine-scale recombination rate variation within and between Drosophila speciesMOHAMED A NOOR; Fiscal Year: 2010..are where does the biologically relevant variation reside and what are the structural, evolutionary, and genetic processes shaping this variation? Meiotic recombination lies at the nexus of these two questions...
- Using whole genomes to study demography and mapping power of a population isolateCHARLESTON CHIANG; Fiscal Year: 2013..Notably, our framework will not only help us understand the history of Sardinia, but can also be extended to other outbred and potentially diverse populations as these datasets become available. ..
- Utilizing a novel liquid-killing assay to gain insight into C. elegans immunityNatalia V Kirienko; Fiscal Year: 2013..In addition, these compounds are likely to prove a more difficult target for the adaptive genetic processes of microbes, as they unbalance the host-pathogen interaction, rather than simply killing the pathogen or ..
- Culture, Mind and Brain: Neural Plasticity and Development in Social ContextShinobu Kitayama; Fiscal Year: 2010..patterning of behavior through social structures, beliefs, and practices) influence biology (for example, genetic processes, brain functioning), and conversely, biology influences culture, with both mutual influences considered over ..
- MATRIX ATTACHMENT REGIONS IN AN IMPRINTED DOMAINJohn Greally; Fiscal Year: 2001....
- FACTORS REGULATING TRANSPOSITION IN C. ELEGANSJohn Collins; Fiscal Year: 1992..These results will be compared with available data for Tc1, providing important information about the extent to which these different element families might respond to the same transposases...
- Evolutionary Genomics of Supersized Mitochondrial GenomesANDREW ALVERSON; Fiscal Year: 2009..A recent study proposed that similar population genetic processes govern the evolution of nuclear and organellar genome size and concluded that the disparity in mitochondrial ..
- INBORN ERRORS OF A PURINE SALVAGE PATHWAYJay Tischfield; Fiscal Year: 2000..A study of DHA-induced gene expression in cultured kidney epithelial cells and whole kidneys is aimed at understanding molecular genetic processes that lead to nephrolithiasis and kidney failure.
- Predoctoral Training Program in Genetic MechanismsJames W Gober; Fiscal Year: 2011..Its rationale is based on the continuing need for research into fundamental genetic processes such as the mechanisms of gene regulation, genetic recombination and transfer, DMA damage and repair, ..
- Human HMGN proteins: role in chromatin & gene functionBarbara Rattner; Fiscal Year: 2007Chromatin is the physiologically relevant substrate for all genetic processes inside eukaryotic nuclei...
- PROSPECTIVE PREDICTORS OF BIPOLAR DISORDERSLaura Sanchez; Fiscal Year: 2002..that developmental dysfunction in fronto-subcortical neural networks mediating emotional processes may play in the pathogenesis of affective illness and the genetic and non-genetic processes that might contribute to such disturbances.
- Functional Genomics of Cryptosporidium parvumGiovanni Widmer; Fiscal Year: 2007..will take advantage of the genomic sequence by converting genomic information into a tool for identifying genetic processes associated with parasite development...
- GENETICS OF DNA REPLICATION IN BACTERIARussell Maurer; Fiscal Year: 1990....
- MAGNETIC FIELD EFFECTS ON MACROPHAGESJoseph Brain; Fiscal Year: 1991..weakly with magnetic fields, and the direct effects of magnetic fields on cellular, biochemical, and genetic processes have not been reproducibly established...
- VERTEBRATE MIDBRAIN AND LIMB DEVELOPMENTRandy Johnson; Fiscal Year: 2001..generated as a result of this work will facilitate future endeavors aimed at defining specific molecular genetic processes which underlie the acquisition of shape and form during animal embryogenesis...
- PILIN GENES OF EIKENELLA CORRODENSRona Hirschberg; Fiscal Year: 1993..corrodens pilin gene(s), and to determine whether pilin gene expression undergoes phase variation. Biochemical, molecular genetic and immunological approaches will be used to address these issues...
- CLINICAL TRIALS OF A GENETICALLY ENGINEERED HCMVGeorge Kemble; Fiscal Year: 1999..They successfully developed molecular genetic processes to engineer HCMV...
- AREA: Translational Roles of the Ribosomal E siteJames Curran; Fiscal Year: 2009..Second, this work will contribute to the research environment at Wake Forest University. Finally, it will contribute to the research training of BS- and MS-level students who are destined for biomedical careers. ..
- Math5 Regulatory Pathway in Retinal DevelopmentLin Gan; Fiscal Year: 2010..Studies to identify genes and genetic processes essential for the formation of retinal neurons will provide the foundation for retinal regeneration...
- Salmonella Gene Expression in Complex EnvironmentsMichael McClelland; Fiscal Year: 2004..What are the genetic processes that underlie the interaction of a pathogen with commensal or symbiotic microbiota? These are difficult ..
- MOLECULAR BASIS OF SNELL DWARF AND LITTLE LONGEVITYJohn Papaconstantinou; Fiscal Year: 2003..dwarf mutants are strikingly similar, these mice provide an excellent resource to study the molecular and genetic processes that determine longevity in vertebrates...
- DISEASE ON NEW HOSTS: MICROBOTRYUM AS A MODEL SYSTEMJanis Antonovics; Fiscal Year: 2002..predictive approach to the study of host shifts and to attain a basic understanding of the ecological and genetic processes involved...
- NUCLEIC ACID CONFORMATION, PROPERTIES, AND INTERACTIONSWILMA OLSON; Fiscal Year: 2006..interests focus on ligand-induced distortions of B-DNA important to its manipulation and control during genetic processes: (1) the transitions of B-DNA to three closely related helical formsuA-DNA, which is implicated in enzymatic ..
- Epigenetic modifications during hematopoiesisMichael Litt; Fiscal Year: 2006unreadable] DESCRIPTION (provided by applicant): All genetic processes within the nuclei of a eukaryotic cell occur in the context chromatin...
- Variation of D. melanogaster chromosome 4Manyuan Long; Fiscal Year: 2006..These studies should add significantly to the understanding of the evolutionary genetics of the Drosophila fourth chromosome. ..
- RNA STRUCTURE DURING TRYPANOSOMATID EDITINGGREGORY CONNELL; Fiscal Year: 2001..More than 30 million people in the tropics and subtropics suffer from the diseases caused by these parasites. ..
- GENES FOR VASCULAR MORPHOGENESIS: A GENETIC APPROACHQing Wang; Fiscal Year: 2003..We use the human genetic approach as the window into the genetic processes involved in the development of the heart and blood vessels...
- Hormonal and cell-specific regulation of Dmrt1LESLIE HECKERT; Fiscal Year: 2006..suggests that identification of factors acting upstream and downstream of it will provide insight into the genetic processes that regulate gene expression in the testis and enhance our understanding of the molecular events necessary ..
- A New CT System for Small-Animal ImagingMARTIN CLAJUS; Fiscal Year: 2009..other hand, small animal imaging involves non- invasive imaging techniques that enable molecular targets and genetic processes to be visualized and measured in living laboratory animals...
- Brn-3 Transcription Factors in Retinal DevelopmentLin Gan; Fiscal Year: 2007..Currently, the effective cures and prevention methods remain elusive. Identification of genes and genetic processes important for the formation and survival of retinal neurons will lead to the development of prevention drugs ..
- TRAINING IN BEHAVIORAL NEUROSCIENCEMichael Fanselow; Fiscal Year: 2009We believe that the greatest progress toward understanding neural and genetic processes that contribute to normal and abnormal behavior, cognition and emotion will occur in a context where expertise in neuroscience goes hand in hand ..
- Doppler characterization of embryonic mouse circulationColin Phoon; Fiscal Year: 2005..provided by applicant) Recent advances in molecular cardiology have provided much insight into the genetic processes involved in normal heart development...
- MITOCHONDRIAL DNA OF NORMAL AND MUTANT TRYPANOSOMESKenneth Stuart; Fiscal Year: 2001..These studies are intended increase our understanding of basic molecular genetic processes, especially those which are important to the survival of parasites.
- HOMEBOX GENES IN CARDIAC DEVELOPMENT AND FUNCTIONMichael Kern; Fiscal Year: 2001..Understanding the genetic processes of heart development and function will enhance future treatments for cardiac pathologies...
- Higher-Order Protein-DNA Complexes in Gene RegulationKenneth Zaret; Fiscal Year: 2005..how chromatin structure is modified during the earliest stages of gene regulation will provide fundamental insight into genetic processes that are essential for growth, development, and pathogenesis in humans.
- Determinants of Behavior Problems after DivorceBRIAN D ONOFRIO; Fiscal Year: 2003..abstract_text> ..
- Role of the BCR in B lymphocyte survival and developmentJohn Monroe; Fiscal Year: 2002....
- Full polarization characterization by OCTLihong Wang; Fiscal Year: 2006..Analyze and characterize the temporal healing process of burns in the animal model. ..
- LEPTIN, IGFS AND COLORECTAL ADENOMA CANCER RISKPolly Newcomb; Fiscal Year: 2005..This study may provide insights into the biologic mechanisms whereby obesity is associated with colorectal cancer risk, as well as have practical implications for cancer prevention. ..
- A Twin Study of Cognitive Outcomes in Older Adult CancerMargaret Gatz; Fiscal Year: 2006..Through abstracting data from cancer treatment records and linking them to existing datasets, we will be able to examine possible longer term effects, along with likely covariates, with optimal comparison groups. ..
- Cell Sorting and Molecular Analysis for Minimal Disease DetectionBarbara Zehentner; Fiscal Year: 2006..unreadable] [unreadable] [unreadable]..
- Effects of Stress and Adrenal Functioning on CognitionJILL MATEO; Fiscal Year: 2006....
- MDS Nordian Gammacell-40 Exactor Whole Animal IrradiatorJohn Monroe; Fiscal Year: 2002..abstract_text> ..
- Medications, Genetic Variability & Breast CancerPolly Newcomb; Fiscal Year: 2007..abstract_text> ..
- BIODEMOGRAPHY OF GENETIC DISEASEBRUCE CARNES; Fiscal Year: 2003..The results derived from this award will have relevance for the estimation of lower limits to age-specific death rates, upper limits to human longevity, and forecasting life expectancy and the size of the older population. ..
- DEMENTIA IN SWEDISH TWINSMargaret Gatz; Fiscal Year: 2002..Different diagnostic criteria will be compared. Quantitative indices will be derived from neuropsychological scores and from neuroimaging data subjected to quantitative mapping. ..
- Dementia in Swedish Twins Data ArchivingMargaret Gatz; Fiscal Year: 2008..unreadable] [unreadable] [unreadable] [unreadable]..
- Colon Cancer Pathways: Hyperplastic Polyps and AdenomasPolly Newcomb; Fiscal Year: 2009..The results of this study will have implications for understanding the biology and prevention of colorectal cancer. ..
- Colon Cancer Risk: IGF Polymorphisms/Lifestyle FactorsPolly Newcomb; Fiscal Year: 2003..As an adjunct to an existing study, this is an efficient, valid cost-effective approach to the investigation of the association between polymorphisms and cancer risk. ..
- Intrinsic and extrinsic control of B cells toleranceJohn Monroe; Fiscal Year: 2004..abstract_text> ..
- Hormones and Colon Cancer: Epigenetic Subtypes, Risk, and SurvivalPolly Newcomb; Fiscal Year: 2009....
- FULL-FIELD MUELLER-MATRIX TOMOGRAPHYLihong Wang; Fiscal Year: 2001..The proposed technology will potentially find broad applications in medical diagnostics for superficial lesions such as ocular, skin, and cervical lesions. ..